cmdline: /opt/conda/share/sentieon-202308.03-3/libexec/util sort -r Homo_sapiens_assembly38.fasta -t 31 -o 1136_8DV-T1-TDNA-1_A23MHWWLT4_1.bam --sam2bam -
This software is licensed to bgold@natera.com by Sentieon Inc.
This software is licensed to bgold@natera.com by Sentieon Inc.
version: sentieon-genomics-202308.03
[M::bwa_idx_load_from_disk] read 3171 ALT contigs
[M::main_mem] bwa index loaded in 1873.685 CPU sec, 64.363 real sec
[M::process] read 723810 sequences (100000014 bp) in 1.049 CPU sec, 1.052 real sec...
[M::process] read 723232 sequences (100000194 bp) in 1.529 CPU sec, 1.602 real sec...
[M::process] read 722792 sequences (100000096 bp) in 1.542 CPU sec, 1.568 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20, 291300, 14, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 249, 594)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1416)
[M::mem_pestat] mean and std.dev: (265.06, 173.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1827)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 189, 285)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 589)
[M::mem_pestat] mean and std.dev: (217.18, 111.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 741)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (312, 1309, 1703)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4485)
[M::mem_pestat] mean and std.dev: (1252.07, 1113.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5876)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 255, 932)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2388)
[M::mem_pestat] mean and std.dev: (420.92, 416.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3116)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722902 sequences (100000120 bp) in 1.537 CPU sec, 1.542 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 291256, 16, 17)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (142, 235, 483)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1165)
[M::mem_pestat] mean and std.dev: (271.90, 208.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1506)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 191, 287)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 595)
[M::mem_pestat] mean and std.dev: (218.75, 112.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 749)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (485, 1527, 2307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5951)
[M::mem_pestat] mean and std.dev: (938.54, 753.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7773)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 279, 1378)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3730)
[M::mem_pestat] mean and std.dev: (724.38, 959.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4906)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 291543, 14, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 379, 601)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1359)
[M::mem_pestat] mean and std.dev: (396.72, 226.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1738)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 191, 289)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 601)
[M::mem_pestat] mean and std.dev: (219.48, 113.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 757)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (110, 626, 1993)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5759)
[M::mem_pestat] mean and std.dev: (775.54, 902.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7642)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (270, 1069, 1324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3432)
[M::mem_pestat] mean and std.dev: (690.86, 523.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4486)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 723810 reads in 276.105 CPU sec, 8.917 real sec
[M::mem_process_seqs] Processed 723232 reads in 196.263 CPU sec, 6.373 real sec
[M::mem_process_seqs] Processed 722792 reads in 219.193 CPU sec, 7.123 real sec
sorting block 0, #reads = 1092148 mem = 536877718 peak = 594989056
[M::process] read 722254 sequences (100000058 bp) in 2.280 CPU sec, 2.421 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 291311, 16, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (341, 585, 4859)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13895)
[M::mem_pestat] mean and std.dev: (1875.17, 2323.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 18413)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 191, 291)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 605)
[M::mem_pestat] mean and std.dev: (220.82, 115.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 762)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 283, 835)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2109)
[M::mem_pestat] mean and std.dev: (254.23, 203.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2746)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 270, 599)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1453)
[M::mem_pestat] mean and std.dev: (376.86, 315.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1880)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723400 sequences (100000216 bp) in 1.872 CPU sec, 1.905 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 291453, 15, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 256, 355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 667)
[M::mem_pestat] mean and std.dev: (273.83, 127.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 823)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 192, 293)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 611)
[M::mem_pestat] mean and std.dev: (222.23, 116.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 770)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (68, 446, 1215)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3509)
[M::mem_pestat] mean and std.dev: (654.73, 644.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4656)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (240, 394, 1600)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4320)
[M::mem_pestat] mean and std.dev: (697.77, 656.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5680)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720554 sequences (100000175 bp) in 1.649 CPU sec, 1.651 real sec...
[M::mem_process_seqs] Processed 722902 reads in 186.433 CPU sec, 5.929 real sec
sorting block 1, #reads = 1094002 mem = 536886326 peak = 810471424
[M::mem_process_seqs] Processed 722254 reads in 125.661 CPU sec, 3.992 real sec
sorting block 2, #reads = 1092969 mem = 536879034 peak = 935342080
[M::process] read 719660 sequences (100000114 bp) in 2.234 CPU sec, 2.437 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 291684, 18, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 248, 1071)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2837)
[M::mem_pestat] mean and std.dev: (568.70, 591.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3720)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 190, 288)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 598)
[M::mem_pestat] mean and std.dev: (218.81, 113.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 753)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (261, 458, 1318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3432)
[M::mem_pestat] mean and std.dev: (878.22, 819.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4489)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 248, 815)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2089)
[M::mem_pestat] mean and std.dev: (410.66, 391.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2726)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 719334 sequences (100000025 bp) in 1.707 CPU sec, 1.723 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 290960, 12, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 422, 1097)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2961)
[M::mem_pestat] mean and std.dev: (746.32, 804.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3963)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 196, 300)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 628)
[M::mem_pestat] mean and std.dev: (227.32, 120.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 792)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (546, 656, 3174)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8430)
[M::mem_pestat] mean and std.dev: (1429.00, 1399.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11058)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 529, 718)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1738)
[M::mem_pestat] mean and std.dev: (477.68, 275.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2248)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 723400 reads in 184.238 CPU sec, 5.983 real sec
[M::mem_process_seqs] Processed 720554 reads in 126.037 CPU sec, 4.137 real sec
sorting block 3, #reads = 1092533 mem = 536877431 peak = 935342080
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 290010, 22, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (133, 232, 624)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1606)
[M::mem_pestat] mean and std.dev: (233.70, 126.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2097)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 197, 303)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 637)
[M::mem_pestat] mean and std.dev: (229.34, 122.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 804)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (328, 566, 2357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6415)
[M::mem_pestat] mean and std.dev: (1307.00, 1338.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8444)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (237, 491, 721)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1689)
[M::mem_pestat] mean and std.dev: (427.53, 251.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2173)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 718996 sequences (100000206 bp) in 2.124 CPU sec, 2.460 real sec...
[M::process] read 719452 sequences (100000058 bp) in 1.675 CPU sec, 1.678 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23, 290497, 17, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 311, 449)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 915)
[M::mem_pestat] mean and std.dev: (289.71, 125.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1148)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 198, 304)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 638)
[M::mem_pestat] mean and std.dev: (229.76, 122.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 805)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 779, 1553)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4353)
[M::mem_pestat] mean and std.dev: (935.31, 903.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5753)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 256, 653)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1617)
[M::mem_pestat] mean and std.dev: (460.50, 401.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2099)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 719660 reads in 183.622 CPU sec, 5.958 real sec
sorting block 4, #reads = 1093009 mem = 536878427 peak = 935342080
[M::mem_process_seqs] Processed 719334 reads in 124.229 CPU sec, 4.199 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 289873, 15, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 219, 517)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1209)
[M::mem_pestat] mean and std.dev: (282.79, 184.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1555)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 198, 305)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 641)
[M::mem_pestat] mean and std.dev: (230.29, 122.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 809)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (426, 1331, 1389)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3315)
[M::mem_pestat] mean and std.dev: (1003.86, 737.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4278)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (234, 305, 621)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1395)
[M::mem_pestat] mean and std.dev: (453.47, 376.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1961)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 717002 sequences (100000064 bp) in 2.310 CPU sec, 2.623 real sec...
[M::process] read 717502 sequences (100000002 bp) in 1.698 CPU sec, 1.714 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (21, 290186, 7, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (133, 216, 244)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 466)
[M::mem_pestat] mean and std.dev: (173.06, 49.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 577)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 196, 298)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 622)
[M::mem_pestat] mean and std.dev: (225.81, 117.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 784)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (265, 343, 1457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3841)
[M::mem_pestat] mean and std.dev: (785.06, 810.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5033)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 718996 reads in 188.013 CPU sec, 6.293 real sec
sorting block 5, #reads = 1092118 mem = 536883274 peak = 935342080
[M::mem_process_seqs] Processed 719452 reads in 124.374 CPU sec, 4.063 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 289747, 24, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 480, 1591)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4345)
[M::mem_pestat] mean and std.dev: (779.32, 682.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5722)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
sorting block 6, #reads = 1091528 mem = 536879157 peak = 935342080
[M::mem_pestat] (25, 50, 75) percentile: (139, 202, 308)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 646)
[M::mem_pestat] mean and std.dev: (232.93, 123.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 815)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (612, 996, 1664)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3768)
[M::mem_pestat] mean and std.dev: (915.27, 643.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4820)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 314, 565)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1333)
[M::mem_pestat] mean and std.dev: (374.89, 247.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1717)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 716108 sequences (100000262 bp) in 2.270 CPU sec, 2.553 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 289630, 33, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (121, 247, 1593)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4537)
[M::mem_pestat] mean and std.dev: (701.52, 922.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6009)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 201, 308)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 648)
[M::mem_pestat] mean and std.dev: (232.51, 123.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 818)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (582, 969, 1193)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2415)
[M::mem_pestat] mean and std.dev: (843.41, 417.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3026)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 357, 510)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1164)
[M::mem_pestat] mean and std.dev: (313.39, 217.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1491)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 716016 sequences (100000178 bp) in 1.921 CPU sec, 1.971 real sec...
[M::mem_process_seqs] Processed 717002 reads in 187.610 CPU sec, 6.135 real sec
[M::mem_process_seqs] Processed 717502 reads in 123.607 CPU sec, 3.979 real sec
sorting block 7, #reads = 1089887 mem = 536876839 peak = 935342080
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 288664, 19, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 260, 493)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1069)
[M::mem_pestat] mean and std.dev: (295.77, 159.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1357)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (140, 203, 309)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 647)
[M::mem_pestat] mean and std.dev: (233.71, 122.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 816)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (113, 549, 1366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3872)
[M::mem_pestat] mean and std.dev: (774.42, 838.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5125)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 272, 316)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 626)
[M::mem_pestat] mean and std.dev: (218.00, 72.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 781)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 716448 sequences (100000040 bp) in 2.387 CPU sec, 2.613 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 289100, 16, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (297, 655, 1593)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4185)
[M::mem_pestat] mean and std.dev: (717.20, 491.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5481)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (140, 203, 308)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 644)
[M::mem_pestat] mean and std.dev: (233.60, 122.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 812)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (568, 1169, 7278)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 20698)
[M::mem_pestat] mean and std.dev: (2646.81, 2987.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 27408)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 227, 526)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1262)
[M::mem_pestat] mean and std.dev: (348.79, 254.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1630)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 716482 sequences (100000002 bp) in 1.560 CPU sec, 1.572 real sec...
[M::mem_process_seqs] Processed 716108 reads in 187.351 CPU sec, 6.140 real sec
sorting block 8, #reads = 1090110 mem = 536876708 peak = 935342080
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 289198, 15, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 320, 533)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1157)
[M::mem_pestat] mean and std.dev: (357.04, 197.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1469)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (139, 202, 307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 643)
[M::mem_pestat] mean and std.dev: (232.49, 122.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 811)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (265, 649, 957)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2341)
[M::mem_pestat] mean and std.dev: (481.25, 349.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3033)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 383, 2577)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7375)
[M::mem_pestat] mean and std.dev: (1292.17, 1597.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9774)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 716120 sequences (100000198 bp) in 2.129 CPU sec, 2.229 real sec...
[M::mem_process_seqs] Processed 716448 reads in 111.309 CPU sec, 3.624 real sec
[M::mem_process_seqs] Processed 716016 reads in 276.540 CPU sec, 8.976 real sec
sorting block 9, #reads = 1089397 mem = 536877916 peak = 935342080
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23, 288912, 23, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 279, 889)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2249)
[M::mem_pestat] mean and std.dev: (518.13, 440.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2929)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (139, 202, 305)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 637)
[M::mem_pestat] mean and std.dev: (231.42, 121.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 803)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (599, 1778, 2669)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6809)
[M::mem_pestat] mean and std.dev: (2119.52, 1923.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9815)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (241, 344, 1709)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4645)
[M::mem_pestat] mean and std.dev: (834.67, 803.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6113)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 715526 sequences (100000236 bp) in 2.253 CPU sec, 2.919 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 289280, 23, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 629, 1514)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4218)
[M::mem_pestat] mean and std.dev: (678.24, 716.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5570)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (139, 203, 308)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 646)
[M::mem_pestat] mean and std.dev: (233.10, 122.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 815)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (554, 1142, 1760)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4172)
[M::mem_pestat] mean and std.dev: (1125.09, 858.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5378)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 355, 1561)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4269)
[M::mem_pestat] mean and std.dev: (673.64, 805.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5623)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 716482 reads in 207.207 CPU sec, 6.685 real sec
[M::process] read 715036 sequences (100000090 bp) in 2.141 CPU sec, 2.190 real sec...
[M::mem_process_seqs] Processed 716120 reads in 128.801 CPU sec, 4.305 real sec
sorting block 10, #reads = 1087896 mem = 536884876 peak = 935342080
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 288692, 21, 21)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 398, 1027)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2783)
[M::mem_pestat] mean and std.dev: (511.00, 469.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3661)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (140, 204, 311)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 653)
[M::mem_pestat] mean and std.dev: (234.65, 123.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 824)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (141, 602, 1750)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4968)
[M::mem_pestat] mean and std.dev: (900.57, 856.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6577)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (285, 471, 1488)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3894)
[M::mem_pestat] mean and std.dev: (713.11, 665.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5097)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 721162 sequences (100000136 bp) in 2.315 CPU sec, 2.535 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 288785, 9, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 266, 396)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 850)
[M::mem_pestat] mean and std.dev: (259.67, 100.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1077)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (141, 206, 313)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 657)
[M::mem_pestat] mean and std.dev: (236.55, 124.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 829)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 255, 351)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 683)
[M::mem_pestat] mean and std.dev: (235.51, 89.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 849)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 723544 sequences (100000071 bp) in 2.045 CPU sec, 2.093 real sec...
[M::mem_process_seqs] Processed 715526 reads in 188.796 CPU sec, 6.264 real sec
sorting block 11, #reads = 1088378 mem = 536879446 peak = 935342080
[M::mem_process_seqs] Processed 715036 reads in 129.369 CPU sec, 4.219 real sec
sorting block 12, #reads = 1088764 mem = 536881498 peak = 935342080
[M::process] read 722870 sequences (100000100 bp) in 2.557 CPU sec, 2.928 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 291291, 13, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 278, 419)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 953)
[M::mem_pestat] mean and std.dev: (340.28, 217.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1220)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 190, 288)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 598)
[M::mem_pestat] mean and std.dev: (218.59, 113.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 753)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (20, 470, 1292)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3836)
[M::mem_pestat] mean and std.dev: (643.85, 593.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5108)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (234, 366, 1192)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3108)
[M::mem_pestat] mean and std.dev: (650.32, 690.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4066)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722566 sequences (100000238 bp) in 1.855 CPU sec, 1.898 real sec...
[M::mem_process_seqs] Processed 723544 reads in 110.362 CPU sec, 3.536 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 291164, 9, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 315, 872)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2188)
[M::mem_pestat] mean and std.dev: (585.21, 541.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2846)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 194, 296)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 618)
[M::mem_pestat] mean and std.dev: (224.40, 118.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 779)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 233, 431)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 985)
[M::mem_pestat] mean and std.dev: (263.82, 144.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1262)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 291535, 13, 20)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 234, 882)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2342)
[M::mem_pestat] mean and std.dev: (438.96, 415.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3072)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 191, 290)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 604)
[M::mem_pestat] mean and std.dev: (220.22, 115.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 761)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (495, 779, 1550)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3660)
[M::mem_pestat] mean and std.dev: (976.08, 709.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4715)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 244, 457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1009)
[M::mem_pestat] mean and std.dev: (284.32, 170.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1285)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 721162 reads in 291.616 CPU sec, 9.500 real sec
[M::process] read 722696 sequences (100000131 bp) in 2.041 CPU sec, 2.054 real sec...
sorting block 13, #reads = 1093183 mem = 536878709 peak = 935342080
[M::mem_process_seqs] Processed 722870 reads in 147.928 CPU sec, 4.788 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 291323, 9, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (117, 360, 762)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2052)
[M::mem_pestat] mean and std.dev: (385.64, 427.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2697)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 192, 292)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 608)
[M::mem_pestat] mean and std.dev: (221.58, 116.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 766)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (247, 309, 1348)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3550)
[M::mem_pestat] mean and std.dev: (477.22, 501.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4651)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 14, #reads = 1093058 mem = 536881246 peak = 935342080
[M::process] read 721692 sequences (100000267 bp) in 2.645 CPU sec, 3.038 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 291547, 9, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 368, 1856)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5256)
[M::mem_pestat] mean and std.dev: (598.97, 748.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6956)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 193, 293)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 611)
[M::mem_pestat] mean and std.dev: (222.21, 116.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 770)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (258, 373, 612)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1320)
[M::mem_pestat] mean and std.dev: (358.26, 201.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1674)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 722566 reads in 184.304 CPU sec, 6.173 real sec
[M::process] read 721288 sequences (100000203 bp) in 2.072 CPU sec, 2.085 real sec...
[M::mem_process_seqs] Processed 722696 reads in 125.655 CPU sec, 4.274 real sec
sorting block 15, #reads = 1093523 mem = 536877188 peak = 935342080
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 291396, 15, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 303, 687)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1719)
[M::mem_pestat] mean and std.dev: (343.41, 289.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2235)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 193, 297)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 623)
[M::mem_pestat] mean and std.dev: (224.47, 119.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 786)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (240, 1066, 1298)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3414)
[M::mem_pestat] mean and std.dev: (741.43, 526.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4472)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (263, 404, 1856)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5042)
[M::mem_pestat] mean and std.dev: (865.00, 758.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6635)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 719974 sequences (100000071 bp) in 2.385 CPU sec, 2.881 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 291689, 15, 24)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (134, 163, 543)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1361)
[M::mem_pestat] mean and std.dev: (340.12, 355.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1770)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 194, 299)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 627)
[M::mem_pestat] mean and std.dev: (226.46, 121.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 791)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (345, 976, 2025)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5385)
[M::mem_pestat] mean and std.dev: (1003.93, 768.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7065)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 217, 975)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2597)
[M::mem_pestat] mean and std.dev: (576.21, 720.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3458)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 719102 sequences (100000206 bp) in 2.056 CPU sec, 2.063 real sec...
[M::mem_process_seqs] Processed 721692 reads in 184.264 CPU sec, 6.210 real sec
[M::mem_process_seqs] Processed 721288 reads in 122.482 CPU sec, 4.012 real sec
sorting block 16, #reads = 1094016 mem = 536885093 peak = 935342080
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 290656, 12, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 225, 516)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1230)
[M::mem_pestat] mean and std.dev: (298.41, 241.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1587)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 197, 303)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 637)
[M::mem_pestat] mean and std.dev: (229.16, 122.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 804)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 1785, 2084)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5836)
[M::mem_pestat] mean and std.dev: (1444.67, 1329.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7712)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 214, 538)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1278)
[M::mem_pestat] mean and std.dev: (279.77, 186.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1648)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 719126 sequences (100000131 bp) in 2.776 CPU sec, 3.226 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 290231, 27, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (236, 392, 453)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 887)
[M::mem_pestat] mean and std.dev: (332.97, 165.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1104)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 198, 305)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 641)
[M::mem_pestat] mean and std.dev: (230.52, 123.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 809)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (412, 685, 1689)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4243)
[M::mem_pestat] mean and std.dev: (959.12, 839.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5520)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 303, 768)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1902)
[M::mem_pestat] mean and std.dev: (373.84, 310.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2469)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 718292 sequences (100000275 bp) in 1.689 CPU sec, 1.697 real sec...
[M::mem_process_seqs] Processed 719974 reads in 188.955 CPU sec, 6.194 real sec
sorting block 17, #reads = 1093787 mem = 536880401 peak = 935342080
[M::mem_process_seqs] Processed 719102 reads in 125.478 CPU sec, 4.018 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 290168, 12, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (122, 174, 720)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1916)
[M::mem_pestat] mean and std.dev: (375.73, 458.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2514)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 199, 305)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 641)
[M::mem_pestat] mean and std.dev: (230.76, 123.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 809)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (471, 690, 1540)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3678)
[M::mem_pestat] mean and std.dev: (813.00, 610.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4747)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 275, 847)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2171)
[M::mem_pestat] mean and std.dev: (427.59, 447.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2833)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 18, #reads = 1092838 mem = 536879827 peak = 948461568
[M::process] read 717312 sequences (100000201 bp) in 2.671 CPU sec, 2.968 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 290099, 15, 16)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 267, 740)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1834)
[M::mem_pestat] mean and std.dev: (354.39, 318.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2381)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 200, 306)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 642)
[M::mem_pestat] mean and std.dev: (231.79, 123.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 810)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (569, 569, 866)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1460)
[M::mem_pestat] mean and std.dev: (543.46, 321.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1830)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 523, 629)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1517)
[M::mem_pestat] mean and std.dev: (405.00, 220.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1961)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 717068 sequences (100000067 bp) in 1.836 CPU sec, 1.846 real sec...
[M::mem_process_seqs] Processed 719126 reads in 188.448 CPU sec, 6.148 real sec
[M::mem_process_seqs] Processed 718292 reads in 124.347 CPU sec, 4.052 real sec
sorting block 19, #reads = 1092141 mem = 536880354 peak = 948461568
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 289073, 24, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (225, 298, 1474)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3972)
[M::mem_pestat] mean and std.dev: (834.11, 969.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5221)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 202, 309)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 651)
[M::mem_pestat] mean and std.dev: (233.84, 124.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 822)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (291, 585, 3286)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9276)
[M::mem_pestat] mean and std.dev: (1845.46, 2022.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12271)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (256, 334, 1490)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3958)
[M::mem_pestat] mean and std.dev: (613.41, 592.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5192)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 716880 sequences (100000216 bp) in 2.383 CPU sec, 2.741 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 289778, 17, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 249, 780)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1990)
[M::mem_pestat] mean and std.dev: (383.23, 356.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2595)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (139, 202, 310)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 652)
[M::mem_pestat] mean and std.dev: (234.26, 124.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 823)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1341, 1778, 2199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3915)
[M::mem_pestat] mean and std.dev: (1581.62, 811.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4826)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 239, 381)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 811)
[M::mem_pestat] mean and std.dev: (249.10, 124.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1026)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 716366 sequences (100000091 bp) in 2.006 CPU sec, 2.014 real sec...
[M::mem_process_seqs] Processed 717312 reads in 188.041 CPU sec, 6.136 real sec
[M::mem_process_seqs] Processed 717068 reads in 124.762 CPU sec, 4.069 real sec
sorting block 20, #reads = 1089424 mem = 536882273 peak = 948461568
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 289170, 13, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 351, 2862)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8198)
[M::mem_pestat] mean and std.dev: (592.24, 829.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10866)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (139, 203, 311)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 655)
[M::mem_pestat] mean and std.dev: (234.55, 124.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 827)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (136, 301, 895)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2413)
[M::mem_pestat] mean and std.dev: (499.69, 488.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3172)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 339, 505)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1085)
[M::mem_pestat] mean and std.dev: (334.91, 178.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1375)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 716286 sequences (100000108 bp) in 2.742 CPU sec, 3.016 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 288751, 19, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 409, 2092)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5908)
[M::mem_pestat] mean and std.dev: (1067.29, 1298.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7816)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (139, 203, 309)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 649)
[M::mem_pestat] mean and std.dev: (233.64, 123.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 819)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (447, 805, 1482)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3552)
[M::mem_pestat] mean and std.dev: (791.71, 515.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4587)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 194, 353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 757)
[M::mem_pestat] mean and std.dev: (207.14, 94.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 959)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 716410 sequences (100000246 bp) in 1.814 CPU sec, 1.824 real sec...
[M::mem_process_seqs] Processed 716880 reads in 189.256 CPU sec, 6.209 real sec
sorting block 21, #reads = 1090297 mem = 536877652 peak = 948461568
[M::mem_process_seqs] Processed 716366 reads in 127.011 CPU sec, 4.111 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 289393, 13, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 492, 1072)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2820)
[M::mem_pestat] mean and std.dev: (527.38, 491.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3694)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (139, 203, 309)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 649)
[M::mem_pestat] mean and std.dev: (233.56, 123.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 819)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (368, 530, 1063)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2453)
[M::mem_pestat] mean and std.dev: (810.08, 691.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3578)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (263, 597, 927)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2255)
[M::mem_pestat] mean and std.dev: (543.29, 408.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2919)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 22, #reads = 1089103 mem = 536878439 peak = 971202560
[M::process] read 716722 sequences (100000127 bp) in 2.550 CPU sec, 2.912 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 289161, 19, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 393, 603)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1383)
[M::mem_pestat] mean and std.dev: (454.12, 291.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1773)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (139, 202, 307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 643)
[M::mem_pestat] mean and std.dev: (232.36, 122.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 811)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 497, 898)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2246)
[M::mem_pestat] mean and std.dev: (606.56, 550.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2920)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 278, 402)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 788)
[M::mem_pestat] mean and std.dev: (261.97, 92.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 981)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 716158 sequences (100000044 bp) in 1.970 CPU sec, 1.974 real sec...
[M::mem_process_seqs] Processed 716286 reads in 191.334 CPU sec, 6.203 real sec
[M::mem_process_seqs] Processed 716410 reads in 128.954 CPU sec, 4.165 real sec
sorting block 23, #reads = 1089672 mem = 536882954 peak = 971202560
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 289777, 17, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 294, 1123)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3049)
[M::mem_pestat] mean and std.dev: (403.79, 386.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4012)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (139, 202, 307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 643)
[M::mem_pestat] mean and std.dev: (232.29, 122.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 811)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (310, 983, 2022)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5446)
[M::mem_pestat] mean and std.dev: (1257.53, 1077.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7158)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (246, 298, 519)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1065)
[M::mem_pestat] mean and std.dev: (332.61, 208.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1338)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 716770 sequences (100000049 bp) in 2.171 CPU sec, 2.501 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 289151, 15, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 247, 538)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1314)
[M::mem_pestat] mean and std.dev: (292.18, 171.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1702)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (139, 203, 308)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 646)
[M::mem_pestat] mean and std.dev: (233.23, 122.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 815)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (577, 681, 1094)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2128)
[M::mem_pestat] mean and std.dev: (587.08, 289.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2645)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 246, 550)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1274)
[M::mem_pestat] mean and std.dev: (274.88, 178.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1636)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 718478 sequences (100000237 bp) in 1.959 CPU sec, 2.052 real sec...
[M::mem_process_seqs] Processed 716722 reads in 187.994 CPU sec, 6.097 real sec
[M::mem_process_seqs] Processed 716158 reads in 128.803 CPU sec, 4.135 real sec
sorting block 24, #reads = 1089699 mem = 536879225 peak = 971202560
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 289296, 28, 21)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 221, 779)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2037)
[M::mem_pestat] mean and std.dev: (395.54, 365.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2666)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (139, 202, 308)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 646)
[M::mem_pestat] mean and std.dev: (232.67, 122.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 815)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (361, 501, 1271)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3091)
[M::mem_pestat] mean and std.dev: (720.00, 578.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4001)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 365, 1310)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3560)
[M::mem_pestat] mean and std.dev: (717.95, 766.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4685)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724674 sequences (100000176 bp) in 2.635 CPU sec, 3.031 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 289335, 9, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (225, 406, 806)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1968)
[M::mem_pestat] mean and std.dev: (476.42, 318.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2549)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 199, 304)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 638)
[M::mem_pestat] mean and std.dev: (229.94, 121.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 805)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (252, 572, 2119)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5853)
[M::mem_pestat] mean and std.dev: (1102.46, 1362.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7720)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 723780 sequences (100000127 bp) in 1.957 CPU sec, 1.965 real sec...
[M::mem_process_seqs] Processed 716770 reads in 192.153 CPU sec, 6.236 real sec
sorting block 25, #reads = 1089149 mem = 536879628 peak = 971202560
[M::mem_process_seqs] Processed 718478 reads in 130.609 CPU sec, 4.207 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 291491, 15, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 283, 312)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (36, 496)
[M::mem_pestat] mean and std.dev: (228.26, 65.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 588)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 188, 284)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 588)
[M::mem_pestat] mean and std.dev: (216.45, 112.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 740)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (419, 732, 2633)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7061)
[M::mem_pestat] mean and std.dev: (1451.27, 1457.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9275)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (325, 365, 593)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1129)
[M::mem_pestat] mean and std.dev: (356.35, 132.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1397)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 26, #reads = 1089807 mem = 536878966 peak = 1005920256
[M::process] read 723098 sequences (100000217 bp) in 2.714 CPU sec, 3.216 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 291594, 19, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 284, 1354)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3694)
[M::mem_pestat] mean and std.dev: (668.84, 825.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4864)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 190, 288)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 598)
[M::mem_pestat] mean and std.dev: (218.98, 114.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 753)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (83, 667, 941)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2657)
[M::mem_pestat] mean and std.dev: (735.26, 638.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3515)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (299, 398, 988)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2366)
[M::mem_pestat] mean and std.dev: (656.86, 587.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3055)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722950 sequences (100000179 bp) in 1.867 CPU sec, 2.080 real sec...
[M::mem_process_seqs] Processed 724674 reads in 190.035 CPU sec, 6.139 real sec
[M::mem_process_seqs] Processed 723780 reads in 131.058 CPU sec, 4.447 real sec
sorting block 27, #reads = 1092579 mem = 536878927 peak = 1005920256
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 291979, 18, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 231, 843)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2223)
[M::mem_pestat] mean and std.dev: (418.26, 473.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2913)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 191, 291)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 607)
[M::mem_pestat] mean and std.dev: (220.80, 115.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 765)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 1163, 2402)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6820)
[M::mem_pestat] mean and std.dev: (1525.33, 1421.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9029)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 408, 1277)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3493)
[M::mem_pestat] mean and std.dev: (632.72, 647.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4601)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 721500 sequences (100000098 bp) in 2.690 CPU sec, 3.027 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 291664, 14, 22)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 442, 818)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2114)
[M::mem_pestat] mean and std.dev: (587.15, 531.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2762)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 192, 292)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 608)
[M::mem_pestat] mean and std.dev: (221.30, 116.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 766)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (75, 644, 1130)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3240)
[M::mem_pestat] mean and std.dev: (570.00, 461.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4295)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (257, 541, 578)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1220)
[M::mem_pestat] mean and std.dev: (399.53, 240.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1541)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 721364 sequences (100000171 bp) in 2.026 CPU sec, 2.043 real sec...
[M::mem_process_seqs] Processed 723098 reads in 194.624 CPU sec, 6.513 real sec
[M::mem_process_seqs] Processed 722950 reads in 132.448 CPU sec, 4.291 real sec
sorting block 28, #reads = 1093905 mem = 536881443 peak = 1005920256
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20, 290730, 27, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (236, 586, 1342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3554)
[M::mem_pestat] mean and std.dev: (625.65, 598.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4660)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 193, 295)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 615)
[M::mem_pestat] mean and std.dev: (223.69, 117.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 775)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (62, 540, 1331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3869)
[M::mem_pestat] mean and std.dev: (808.11, 937.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5138)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (254, 425, 777)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1823)
[M::mem_pestat] mean and std.dev: (459.05, 301.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2346)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720178 sequences (100000110 bp) in 2.565 CPU sec, 2.854 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 291757, 23, 23)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 205, 558)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1340)
[M::mem_pestat] mean and std.dev: (300.25, 236.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1731)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 194, 297)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 621)
[M::mem_pestat] mean and std.dev: (225.03, 119.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 783)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (134, 313, 685)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1787)
[M::mem_pestat] mean and std.dev: (324.89, 285.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2338)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 335, 435)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 989)
[M::mem_pestat] mean and std.dev: (330.91, 217.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1266)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 719586 sequences (100000019 bp) in 2.106 CPU sec, 2.223 real sec...
[M::mem_process_seqs] Processed 721500 reads in 189.490 CPU sec, 6.114 real sec
sorting block 29, #reads = 1092538 mem = 536878519 peak = 1005920256
[M::mem_process_seqs] Processed 721364 reads in 130.242 CPU sec, 4.223 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 290908, 22, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 394, 1181)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3111)
[M::mem_pestat] mean and std.dev: (721.46, 813.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4076)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 197, 302)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 634)
[M::mem_pestat] mean and std.dev: (228.51, 122.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 800)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (99, 531, 1588)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4566)
[M::mem_pestat] mean and std.dev: (874.29, 950.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6055)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 319, 394)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 814)
[M::mem_pestat] mean and std.dev: (279.61, 134.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1024)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 30, #reads = 1091937 mem = 536880291 peak = 1020952576
[M::process] read 719266 sequences (100000107 bp) in 2.724 CPU sec, 3.155 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 290338, 21, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 446, 2131)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5971)
[M::mem_pestat] mean and std.dev: (1076.26, 1204.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7891)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 197, 303)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 637)
[M::mem_pestat] mean and std.dev: (229.07, 122.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 804)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (76, 1071, 2653)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7807)
[M::mem_pestat] mean and std.dev: (1556.19, 1751.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10384)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 369, 922)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2370)
[M::mem_pestat] mean and std.dev: (573.00, 501.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3094)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 720178 reads in 191.898 CPU sec, 6.269 real sec
[M::process] read 718892 sequences (100000149 bp) in 2.043 CPU sec, 2.125 real sec...
[M::mem_process_seqs] Processed 719586 reads in 130.474 CPU sec, 4.355 real sec
sorting block 31, #reads = 1092298 mem = 536877670 peak = 1020952576
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 290153, 16, 24)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (146, 238, 450)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1058)
[M::mem_pestat] mean and std.dev: (281.77, 185.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1362)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 198, 303)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 637)
[M::mem_pestat] mean and std.dev: (229.50, 122.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 804)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (436, 843, 1695)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4213)
[M::mem_pestat] mean and std.dev: (984.00, 783.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5472)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (278, 394, 715)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1589)
[M::mem_pestat] mean and std.dev: (387.95, 216.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2026)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 718906 sequences (100000291 bp) in 2.573 CPU sec, 3.146 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 290570, 22, 24)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 302, 991)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2579)
[M::mem_pestat] mean and std.dev: (447.32, 347.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3373)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 199, 307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 647)
[M::mem_pestat] mean and std.dev: (231.28, 123.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 817)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (293, 565, 1201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3017)
[M::mem_pestat] mean and std.dev: (635.55, 415.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3925)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (236, 264, 677)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1559)
[M::mem_pestat] mean and std.dev: (378.00, 287.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2000)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 718602 sequences (100000059 bp) in 1.984 CPU sec, 2.004 real sec...
[M::mem_process_seqs] Processed 719266 reads in 194.308 CPU sec, 6.452 real sec
[M::mem_process_seqs] Processed 718892 reads in 128.853 CPU sec, 4.232 real sec
sorting block 32, #reads = 1090862 mem = 536879863 peak = 1020952576
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 289798, 14, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (276, 444, 746)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1686)
[M::mem_pestat] mean and std.dev: (506.75, 372.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2156)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 198, 304)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 638)
[M::mem_pestat] mean and std.dev: (229.82, 122.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 805)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (91, 276, 518)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1372)
[M::mem_pestat] mean and std.dev: (343.71, 283.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1799)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 220, 479)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1109)
[M::mem_pestat] mean and std.dev: (281.96, 163.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1424)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 718430 sequences (100000151 bp) in 2.588 CPU sec, 2.874 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 289982, 11, 19)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 451, 748)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1818)
[M::mem_pestat] mean and std.dev: (510.49, 381.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2353)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 198, 303)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 635)
[M::mem_pestat] mean and std.dev: (229.48, 121.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 801)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (900, 1164, 2053)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4359)
[M::mem_pestat] mean and std.dev: (1037.00, 768.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5512)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 354, 709)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1835)
[M::mem_pestat] mean and std.dev: (409.12, 354.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2398)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 717680 sequences (100000017 bp) in 2.024 CPU sec, 2.028 real sec...
[M::mem_process_seqs] Processed 718906 reads in 197.615 CPU sec, 6.433 real sec
sorting block 33, #reads = 1091492 mem = 536877994 peak = 1020952576
[M::mem_process_seqs] Processed 718602 reads in 131.107 CPU sec, 4.219 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 289978, 24, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (139, 209, 583)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1471)
[M::mem_pestat] mean and std.dev: (266.36, 205.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1915)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 198, 302)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 632)
[M::mem_pestat] mean and std.dev: (229.22, 121.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 797)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (514, 1267, 2432)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6268)
[M::mem_pestat] mean and std.dev: (1433.64, 1461.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8186)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 225, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 660)
[M::mem_pestat] mean and std.dev: (220.18, 85.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 827)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 34, #reads = 1089735 mem = 536878312 peak = 1023442944
[M::process] read 718156 sequences (100000031 bp) in 2.492 CPU sec, 2.779 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 289322, 23, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 344, 1050)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2806)
[M::mem_pestat] mean and std.dev: (556.62, 581.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3684)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 199, 302)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 630)
[M::mem_pestat] mean and std.dev: (229.16, 119.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 794)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (68, 134, 452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1220)
[M::mem_pestat] mean and std.dev: (170.79, 159.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1604)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 309, 538)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1282)
[M::mem_pestat] mean and std.dev: (354.18, 242.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1654)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 718156 sequences (100000293 bp) in 2.080 CPU sec, 2.123 real sec...
[M::mem_process_seqs] Processed 718430 reads in 196.181 CPU sec, 6.342 real sec
[M::mem_process_seqs] Processed 717680 reads in 131.554 CPU sec, 4.203 real sec
sorting block 35, #reads = 1090748 mem = 536880125 peak = 1023442944
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 289898, 20, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 277, 798)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2012)
[M::mem_pestat] mean and std.dev: (442.26, 430.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2619)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 198, 302)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 632)
[M::mem_pestat] mean and std.dev: (228.98, 120.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 797)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (546, 709, 2729)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7095)
[M::mem_pestat] mean and std.dev: (1436.79, 1521.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9278)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 506, 632)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1450)
[M::mem_pestat] mean and std.dev: (479.95, 311.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1859)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 716912 sequences (100000104 bp) in 2.479 CPU sec, 3.105 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 289853, 18, 22)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 327, 749)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1897)
[M::mem_pestat] mean and std.dev: (463.68, 360.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2471)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 199, 303)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 633)
[M::mem_pestat] mean and std.dev: (229.55, 120.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 798)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (243, 865, 1703)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4623)
[M::mem_pestat] mean and std.dev: (1123.39, 1074.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6083)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 228, 380)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 784)
[M::mem_pestat] mean and std.dev: (229.58, 93.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 986)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 718156 reads in 191.961 CPU sec, 6.212 real sec
[M::process] read 716818 sequences (100000113 bp) in 2.181 CPU sec, 2.300 real sec...
[M::mem_process_seqs] Processed 718156 reads in 132.368 CPU sec, 4.450 real sec
sorting block 36, #reads = 1090230 mem = 536879060 peak = 1023442944
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 289266, 16, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 259, 674)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1684)
[M::mem_pestat] mean and std.dev: (463.61, 431.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2189)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (139, 201, 305)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 637)
[M::mem_pestat] mean and std.dev: (231.36, 121.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 803)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (647, 1136, 1990)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4676)
[M::mem_pestat] mean and std.dev: (922.93, 721.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6019)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (242, 362, 1659)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4493)
[M::mem_pestat] mean and std.dev: (927.36, 968.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5910)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 716624 sequences (100000134 bp) in 2.605 CPU sec, 3.021 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 289652, 19, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 328, 645)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1573)
[M::mem_pestat] mean and std.dev: (354.95, 282.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2037)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (139, 201, 307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 643)
[M::mem_pestat] mean and std.dev: (232.01, 122.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 811)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (449, 584, 1334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3104)
[M::mem_pestat] mean and std.dev: (547.00, 395.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3989)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 335, 1280)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3412)
[M::mem_pestat] mean and std.dev: (783.77, 787.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4478)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 716884 sequences (100000021 bp) in 1.999 CPU sec, 2.058 real sec...
[M::mem_process_seqs] Processed 716912 reads in 189.749 CPU sec, 6.313 real sec
sorting block 37, #reads = 1090068 mem = 536879018 peak = 1023442944
[M::mem_process_seqs] Processed 716818 reads in 126.083 CPU sec, 4.115 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 289188, 18, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 273, 1422)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3958)
[M::mem_pestat] mean and std.dev: (544.92, 610.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5226)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (139, 202, 308)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 646)
[M::mem_pestat] mean and std.dev: (232.47, 122.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 815)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (123, 795, 2559)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7431)
[M::mem_pestat] mean and std.dev: (1056.44, 1160.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9867)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 370, 1028)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2764)
[M::mem_pestat] mean and std.dev: (446.92, 437.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3632)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 38, #reads = 1088837 mem = 536878491 peak = 1039360000
[M::process] read 724020 sequences (100000247 bp) in 2.590 CPU sec, 2.992 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 289363, 23, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 405, 944)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2498)
[M::mem_pestat] mean and std.dev: (595.39, 551.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3275)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (139, 202, 307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 643)
[M::mem_pestat] mean and std.dev: (232.39, 122.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 811)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (23, 365, 1351)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4007)
[M::mem_pestat] mean and std.dev: (767.14, 1011.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5335)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 283, 392)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 788)
[M::mem_pestat] mean and std.dev: (273.48, 89.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 986)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 716624 reads in 188.012 CPU sec, 6.155 real sec
[M::process] read 723382 sequences (100000299 bp) in 2.133 CPU sec, 2.409 real sec...
[M::mem_process_seqs] Processed 716884 reads in 130.540 CPU sec, 4.192 real sec
sorting block 39, #reads = 1086823 mem = 536876854 peak = 1039360000
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 291922, 17, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 294, 925)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2381)
[M::mem_pestat] mean and std.dev: (531.27, 472.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3109)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 190, 288)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 598)
[M::mem_pestat] mean and std.dev: (218.48, 114.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 753)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (425, 675, 1289)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3017)
[M::mem_pestat] mean and std.dev: (827.38, 749.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3881)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 238, 1367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3781)
[M::mem_pestat] mean and std.dev: (647.42, 850.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4988)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722828 sequences (100000150 bp) in 2.479 CPU sec, 2.969 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 291715, 11, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 527, 1008)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2642)
[M::mem_pestat] mean and std.dev: (482.39, 354.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3459)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 191, 290)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 604)
[M::mem_pestat] mean and std.dev: (220.09, 115.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 761)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (525, 984, 1348)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2994)
[M::mem_pestat] mean and std.dev: (804.55, 526.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3817)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (238, 394, 1237)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3235)
[M::mem_pestat] mean and std.dev: (642.00, 602.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4234)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722098 sequences (100000260 bp) in 1.943 CPU sec, 1.950 real sec...
[M::mem_process_seqs] Processed 724020 reads in 194.707 CPU sec, 6.530 real sec
[M::mem_process_seqs] Processed 723382 reads in 130.522 CPU sec, 4.266 real sec
sorting block 40, #reads = 1089520 mem = 536879219 peak = 1039360000
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 291465, 21, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 289, 737)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1871)
[M::mem_pestat] mean and std.dev: (346.08, 314.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2438)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 192, 293)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 611)
[M::mem_pestat] mean and std.dev: (221.97, 117.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 770)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 438, 1439)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4021)
[M::mem_pestat] mean and std.dev: (809.30, 701.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5312)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 254, 650)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1640)
[M::mem_pestat] mean and std.dev: (359.07, 309.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2135)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 721372 sequences (100000234 bp) in 2.612 CPU sec, 3.153 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 291496, 17, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 248, 517)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1229)
[M::mem_pestat] mean and std.dev: (246.75, 183.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1585)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 193, 294)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 614)
[M::mem_pestat] mean and std.dev: (223.12, 117.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 774)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (100, 483, 1056)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2968)
[M::mem_pestat] mean and std.dev: (613.65, 701.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3924)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 288, 507)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1083)
[M::mem_pestat] mean and std.dev: (278.90, 118.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1371)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 722828 reads in 188.055 CPU sec, 6.180 real sec
[M::process] read 720440 sequences (100000027 bp) in 2.317 CPU sec, 2.361 real sec...
sorting block 41, #reads = 1095415 mem = 536882879 peak = 1039360000
[M::mem_process_seqs] Processed 722098 reads in 130.943 CPU sec, 4.189 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 291480, 21, 24)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 321, 741)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1875)
[M::mem_pestat] mean and std.dev: (442.74, 393.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2442)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 194, 297)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 621)
[M::mem_pestat] mean and std.dev: (224.94, 119.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 783)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (275, 374, 876)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2078)
[M::mem_pestat] mean and std.dev: (447.79, 359.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2679)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (141, 636, 2132)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6114)
[M::mem_pestat] mean and std.dev: (1179.04, 1409.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8105)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 42, #reads = 1095247 mem = 536875697 peak = 1039360000
[M::process] read 720550 sequences (100000205 bp) in 2.537 CPU sec, 3.115 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 290586, 24, 24)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 345, 878)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2248)
[M::mem_pestat] mean and std.dev: (498.42, 511.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2933)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 196, 300)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 628)
[M::mem_pestat] mean and std.dev: (226.68, 120.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 792)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 398, 833)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2115)
[M::mem_pestat] mean and std.dev: (428.00, 402.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2756)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (247, 292, 666)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1504)
[M::mem_pestat] mean and std.dev: (349.45, 238.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1923)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 721372 reads in 183.464 CPU sec, 5.997 real sec
[M::process] read 719730 sequences (100000223 bp) in 2.173 CPU sec, 2.288 real sec...
[M::mem_process_seqs] Processed 720440 reads in 128.376 CPU sec, 4.149 real sec
sorting block 43, #reads = 1092910 mem = 536879786 peak = 1039360000
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 291090, 12, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 247, 1499)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4155)
[M::mem_pestat] mean and std.dev: (725.64, 881.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5483)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 196, 301)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 631)
[M::mem_pestat] mean and std.dev: (227.71, 121.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 796)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (510, 807, 2265)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5775)
[M::mem_pestat] mean and std.dev: (1302.75, 1358.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7530)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 461, 1818)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5056)
[M::mem_pestat] mean and std.dev: (628.94, 624.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6675)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 719870 sequences (100000075 bp) in 2.695 CPU sec, 3.130 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 290786, 25, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (232, 482, 577)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1267)
[M::mem_pestat] mean and std.dev: (400.82, 227.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1612)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 197, 302)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 634)
[M::mem_pestat] mean and std.dev: (228.57, 121.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 800)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (422, 827, 1791)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4529)
[M::mem_pestat] mean and std.dev: (1212.68, 1271.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6297)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (333, 638, 1979)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5271)
[M::mem_pestat] mean and std.dev: (1029.35, 1105.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6917)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 720550 reads in 186.519 CPU sec, 6.072 real sec
[M::process] read 719152 sequences (100000044 bp) in 2.218 CPU sec, 2.261 real sec...
sorting block 44, #reads = 1093360 mem = 536879680 peak = 1039360000
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 290545, 18, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 743, 1161)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3167)
[M::mem_pestat] mean and std.dev: (746.04, 813.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4170)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 197, 303)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 637)
[M::mem_pestat] mean and std.dev: (229.00, 122.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 804)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (653, 906, 1417)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2945)
[M::mem_pestat] mean and std.dev: (899.29, 624.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3709)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 272, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 780)
[M::mem_pestat] mean and std.dev: (256.54, 141.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 988)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 719288 sequences (100000001 bp) in 2.398 CPU sec, 2.515 real sec...
[M::mem_process_seqs] Processed 719870 reads in 107.939 CPU sec, 3.676 real sec
[M::mem_process_seqs] Processed 719730 reads in 290.494 CPU sec, 9.556 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 289594, 11, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 220, 1093)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2959)
[M::mem_pestat] mean and std.dev: (586.55, 707.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3892)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 197, 303)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 635)
[M::mem_pestat] mean and std.dev: (229.19, 122.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 801)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (445, 638, 1300)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3010)
[M::mem_pestat] mean and std.dev: (756.64, 536.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3865)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (290, 586, 1013)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2459)
[M::mem_pestat] mean and std.dev: (602.06, 439.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3182)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 45, #reads = 1091332 mem = 536877993 peak = 1039360000
[M::process] read 719664 sequences (100000089 bp) in 2.647 CPU sec, 3.221 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 289698, 7, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (139, 616, 1121)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3085)
[M::mem_pestat] mean and std.dev: (550.06, 458.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4067)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 197, 301)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 631)
[M::mem_pestat] mean and std.dev: (228.20, 121.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 796)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 370, 842)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2102)
[M::mem_pestat] mean and std.dev: (515.50, 369.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2732)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 719152 reads in 214.522 CPU sec, 6.991 real sec
[M::mem_process_seqs] Processed 719288 reads in 130.081 CPU sec, 4.217 real sec
[M::process] read 719838 sequences (100000298 bp) in 2.491 CPU sec, 2.701 real sec...
sorting block 46, #reads = 1091927 mem = 536878185 peak = 1039360000
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 290324, 12, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 500, 1791)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5005)
[M::mem_pestat] mean and std.dev: (975.86, 1012.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6612)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 196, 299)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 625)
[M::mem_pestat] mean and std.dev: (226.73, 119.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 788)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (325, 396, 1458)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3724)
[M::mem_pestat] mean and std.dev: (793.08, 883.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4857)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 662, 1298)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3556)
[M::mem_pestat] mean and std.dev: (595.39, 468.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4685)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 719662 sequences (100000091 bp) in 2.678 CPU sec, 3.060 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 290535, 28, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (228, 514, 3718)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10698)
[M::mem_pestat] mean and std.dev: (1469.90, 1871.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14188)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 195, 297)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 619)
[M::mem_pestat] mean and std.dev: (225.51, 118.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 780)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (347, 998, 2323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6275)
[M::mem_pestat] mean and std.dev: (1252.89, 1159.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8251)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 251, 354)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 730)
[M::mem_pestat] mean and std.dev: (264.42, 130.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 918)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 719664 reads in 192.766 CPU sec, 6.203 real sec
[M::process] read 719788 sequences (100000045 bp) in 1.920 CPU sec, 1.978 real sec...
sorting block 47, #reads = 1091370 mem = 536880203 peak = 1039360000
[M::mem_process_seqs] Processed 719838 reads in 131.327 CPU sec, 4.421 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 290322, 28, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 329, 607)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1433)
[M::mem_pestat] mean and std.dev: (407.38, 313.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1846)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 196, 297)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 619)
[M::mem_pestat] mean and std.dev: (225.61, 118.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 780)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (233, 770, 1356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3602)
[M::mem_pestat] mean and std.dev: (774.38, 701.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4725)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (280, 421, 4260)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12220)
[M::mem_pestat] mean and std.dev: (2408.35, 3302.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 16200)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 48, #reads = 1090752 mem = 536880389 peak = 1039360000
[M::process] read 718868 sequences (100000007 bp) in 2.809 CPU sec, 3.155 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 290397, 32, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 418, 1495)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4051)
[M::mem_pestat] mean and std.dev: (813.21, 709.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5329)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 196, 296)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 616)
[M::mem_pestat] mean and std.dev: (224.96, 117.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 776)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 851, 1383)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3775)
[M::mem_pestat] mean and std.dev: (781.45, 606.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4971)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 308, 454)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1002)
[M::mem_pestat] mean and std.dev: (274.72, 145.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1276)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 718800 sequences (100000049 bp) in 1.710 CPU sec, 1.803 real sec...
[M::mem_process_seqs] Processed 719662 reads in 192.389 CPU sec, 6.485 real sec
[M::mem_process_seqs] Processed 719788 reads in 128.762 CPU sec, 4.155 real sec
sorting block 49, #reads = 1091488 mem = 536878481 peak = 1039360000
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20, 290163, 25, 22)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (133, 272, 503)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1243)
[M::mem_pestat] mean and std.dev: (327.68, 249.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1613)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 197, 299)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 623)
[M::mem_pestat] mean and std.dev: (226.70, 118.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 785)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (459, 589, 4501)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12585)
[M::mem_pestat] mean and std.dev: (1855.64, 2401.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 16627)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (230, 467, 792)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1916)
[M::mem_pestat] mean and std.dev: (391.83, 228.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2478)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 718506 sequences (100000024 bp) in 2.691 CPU sec, 3.047 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 290315, 10, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 364, 1256)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3378)
[M::mem_pestat] mean and std.dev: (642.95, 783.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4439)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 198, 300)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 626)
[M::mem_pestat] mean and std.dev: (227.66, 119.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 789)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 763, 1296)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3448)
[M::mem_pestat] mean and std.dev: (622.89, 448.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4524)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 286, 602)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1432)
[M::mem_pestat] mean and std.dev: (327.37, 218.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1847)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 718010 sequences (100000230 bp) in 1.948 CPU sec, 1.990 real sec...
[M::mem_process_seqs] Processed 718868 reads in 195.113 CPU sec, 6.355 real sec
[M::mem_process_seqs] Processed 718800 reads in 127.579 CPU sec, 4.202 real sec
sorting block 50, #reads = 1091325 mem = 536882813 peak = 1039360000
[M::process] read 717878 sequences (100000031 bp) in 2.765 CPU sec, 3.145 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 289398, 11, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 348, 966)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2598)
[M::mem_pestat] mean and std.dev: (528.45, 491.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3414)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 199, 303)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 633)
[M::mem_pestat] mean and std.dev: (229.67, 120.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 798)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (471, 774, 1236)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2766)
[M::mem_pestat] mean and std.dev: (798.91, 464.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3531)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 294, 549)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1269)
[M::mem_pestat] mean and std.dev: (331.83, 252.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1629)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722542 sequences (100000154 bp) in 2.011 CPU sec, 2.027 real sec...
[M::mem_process_seqs] Processed 718010 reads in 110.623 CPU sec, 3.538 real sec
sorting block 51, #reads = 1091510 mem = 536884735 peak = 1039360000
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 289890, 20, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 344, 725)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1825)
[M::mem_pestat] mean and std.dev: (496.68, 468.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2375)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 198, 302)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 632)
[M::mem_pestat] mean and std.dev: (228.79, 120.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 797)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (241, 729, 2455)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6883)
[M::mem_pestat] mean and std.dev: (1226.55, 1159.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9097)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 272, 1162)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3084)
[M::mem_pestat] mean and std.dev: (479.79, 558.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4045)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (21, 289707, 9, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (96, 267, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 816)
[M::mem_pestat] mean and std.dev: (219.44, 122.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1056)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 200, 305)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 639)
[M::mem_pestat] mean and std.dev: (230.59, 121.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 806)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 481, 2472)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7006)
[M::mem_pestat] mean and std.dev: (1292.21, 1826.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9273)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 718506 reads in 293.515 CPU sec, 9.628 real sec
[M::mem_process_seqs] Processed 717878 reads in 152.122 CPU sec, 4.982 real sec
[M::process] read 729092 sequences (100000056 bp) in 2.530 CPU sec, 2.651 real sec...
sorting block 52, #reads = 1089751 mem = 536880466 peak = 1039360000
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 290969, 17, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 186, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 720)
[M::mem_pestat] mean and std.dev: (219.92, 100.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 910)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 191, 290)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 602)
[M::mem_pestat] mean and std.dev: (219.75, 114.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 758)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (127, 340, 1341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3769)
[M::mem_pestat] mean and std.dev: (562.88, 637.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4983)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 441, 1555)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4247)
[M::mem_pestat] mean and std.dev: (872.38, 1011.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5593)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 727732 sequences (100000043 bp) in 2.502 CPU sec, 2.873 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 293553, 19, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (290, 354, 463)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 809)
[M::mem_pestat] mean and std.dev: (349.81, 151.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 982)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 182, 271)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 555)
[M::mem_pestat] mean and std.dev: (206.98, 105.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 697)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (270, 394, 733)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1659)
[M::mem_pestat] mean and std.dev: (421.82, 318.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2122)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 309, 757)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1887)
[M::mem_pestat] mean and std.dev: (451.50, 360.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2452)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726012 sequences (100000093 bp) in 2.048 CPU sec, 2.077 real sec...
[M::mem_process_seqs] Processed 722542 reads in 207.869 CPU sec, 6.706 real sec
sorting block 53, #reads = 1088694 mem = 536878500 peak = 1039360000
[M::mem_process_seqs] Processed 729092 reads in 138.402 CPU sec, 4.423 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 293327, 18, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 314, 601)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1433)
[M::mem_pestat] mean and std.dev: (380.39, 312.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1849)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 184, 274)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 562)
[M::mem_pestat] mean and std.dev: (209.42, 107.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 706)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (322, 900, 1550)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4006)
[M::mem_pestat] mean and std.dev: (736.47, 560.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5234)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 265, 1046)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2744)
[M::mem_pestat] mean and std.dev: (648.31, 719.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3593)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 54, #reads = 1091066 mem = 536886520 peak = 1039360000
[M::process] read 725636 sequences (100000218 bp) in 3.102 CPU sec, 3.435 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (21, 292390, 10, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 242, 926)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2472)
[M::mem_pestat] mean and std.dev: (403.53, 390.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3245)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 186, 280)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 578)
[M::mem_pestat] mean and std.dev: (213.32, 110.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 727)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (432, 1876, 2455)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6501)
[M::mem_pestat] mean and std.dev: (1524.20, 993.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8524)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 284, 558)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1280)
[M::mem_pestat] mean and std.dev: (360.07, 254.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1641)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726590 sequences (100000181 bp) in 2.061 CPU sec, 2.070 real sec...
[M::mem_process_seqs] Processed 727732 reads in 198.536 CPU sec, 6.403 real sec
[M::mem_process_seqs] Processed 726012 reads in 131.772 CPU sec, 4.471 real sec
sorting block 55, #reads = 1092911 mem = 536882535 peak = 1039360000
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 293017, 13, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 293, 611)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1493)
[M::mem_pestat] mean and std.dev: (396.96, 351.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1934)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 186, 281)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 581)
[M::mem_pestat] mean and std.dev: (214.10, 111.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 731)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (95, 579, 1000)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2810)
[M::mem_pestat] mean and std.dev: (577.31, 500.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3715)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 320, 1371)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3755)
[M::mem_pestat] mean and std.dev: (702.62, 757.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4947)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723940 sequences (100000095 bp) in 2.775 CPU sec, 3.187 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 293571, 11, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (262, 387, 1090)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2746)
[M::mem_pestat] mean and std.dev: (543.24, 518.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3574)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 184, 276)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 566)
[M::mem_pestat] mean and std.dev: (210.95, 107.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 711)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (541, 971, 5831)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 16411)
[M::mem_pestat] mean and std.dev: (2847.82, 2693.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 21701)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 360, 1152)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3104)
[M::mem_pestat] mean and std.dev: (658.78, 668.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4080)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723120 sequences (100000012 bp) in 2.002 CPU sec, 2.048 real sec...
[M::mem_process_seqs] Processed 725636 reads in 200.843 CPU sec, 6.699 real sec
[M::mem_process_seqs] Processed 726590 reads in 130.259 CPU sec, 4.262 real sec
sorting block 56, #reads = 1094507 mem = 536879459 peak = 1039360000
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 293172, 21, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 209, 798)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2082)
[M::mem_pestat] mean and std.dev: (515.16, 594.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2892)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 189, 287)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 595)
[M::mem_pestat] mean and std.dev: (218.45, 115.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 749)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (232, 1522, 2953)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8395)
[M::mem_pestat] mean and std.dev: (1707.48, 1553.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11116)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 296, 1152)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3120)
[M::mem_pestat] mean and std.dev: (627.43, 700.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4104)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723148 sequences (100000031 bp) in 2.681 CPU sec, 3.274 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (18, 292060, 11, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (134, 297, 467)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1133)
[M::mem_pestat] mean and std.dev: (285.12, 189.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1466)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 190, 290)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 604)
[M::mem_pestat] mean and std.dev: (220.76, 116.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 761)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (648, 1034, 1540)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3324)
[M::mem_pestat] mean and std.dev: (1097.09, 887.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4645)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 378, 595)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1379)
[M::mem_pestat] mean and std.dev: (395.22, 268.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1771)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723510 sequences (100000008 bp) in 2.065 CPU sec, 2.068 real sec...
[M::mem_process_seqs] Processed 723940 reads in 198.469 CPU sec, 6.484 real sec
sorting block 57, #reads = 1094173 mem = 536879681 peak = 1039360000
[M::mem_process_seqs] Processed 723120 reads in 129.995 CPU sec, 4.152 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 291849, 13, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 427, 443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 929)
[M::mem_pestat] mean and std.dev: (326.28, 153.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1172)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 191, 290)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 604)
[M::mem_pestat] mean and std.dev: (220.79, 116.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 761)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (69, 769, 1414)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4104)
[M::mem_pestat] mean and std.dev: (670.62, 561.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5449)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (242, 347, 947)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2357)
[M::mem_pestat] mean and std.dev: (545.55, 509.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3062)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 58, #reads = 1094361 mem = 536885448 peak = 1039499264
[M::process] read 723172 sequences (100000133 bp) in 2.718 CPU sec, 3.028 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 292047, 13, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 243, 2368)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6738)
[M::mem_pestat] mean and std.dev: (581.58, 851.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8923)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 190, 289)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 601)
[M::mem_pestat] mean and std.dev: (219.88, 116.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 757)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 552, 1347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3579)
[M::mem_pestat] mean and std.dev: (755.00, 794.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4695)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 241, 417)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 867)
[M::mem_pestat] mean and std.dev: (283.21, 165.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1092)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 721866 sequences (100000019 bp) in 2.052 CPU sec, 2.057 real sec...
[M::mem_process_seqs] Processed 723148 reads in 202.078 CPU sec, 6.617 real sec
[M::mem_process_seqs] Processed 723510 reads in 132.991 CPU sec, 4.254 real sec
sorting block 59, #reads = 1092411 mem = 536878372 peak = 1039499264
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 291769, 20, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 342, 548)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1296)
[M::mem_pestat] mean and std.dev: (348.69, 219.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1670)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 189, 286)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 592)
[M::mem_pestat] mean and std.dev: (218.02, 113.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 745)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (525, 980, 2434)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6252)
[M::mem_pestat] mean and std.dev: (1410.55, 1243.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8161)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 382, 646)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1642)
[M::mem_pestat] mean and std.dev: (410.00, 335.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2140)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 721430 sequences (100000296 bp) in 2.758 CPU sec, 3.112 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20, 291431, 23, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 475, 703)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1797)
[M::mem_pestat] mean and std.dev: (415.50, 370.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2344)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 192, 295)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 617)
[M::mem_pestat] mean and std.dev: (223.89, 119.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 778)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (227, 554, 716)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1694)
[M::mem_pestat] mean and std.dev: (449.05, 377.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2183)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 252, 308)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 554)
[M::mem_pestat] mean and std.dev: (226.55, 78.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 677)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 719746 sequences (100000205 bp) in 2.004 CPU sec, 2.021 real sec...
[M::mem_process_seqs] Processed 723172 reads in 206.764 CPU sec, 6.779 real sec
[M::mem_process_seqs] Processed 721866 reads in 134.869 CPU sec, 4.427 real sec
sorting block 60, #reads = 1093021 mem = 536878096 peak = 1039499264
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20, 291518, 17, 24)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 273, 948)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2488)
[M::mem_pestat] mean and std.dev: (494.95, 454.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3258)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 193, 297)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 621)
[M::mem_pestat] mean and std.dev: (225.25, 120.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 783)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (438, 793, 793)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1503)
[M::mem_pestat] mean and std.dev: (561.47, 319.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1858)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 221, 1091)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2933)
[M::mem_pestat] mean and std.dev: (597.71, 573.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3854)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 719168 sequences (100000216 bp) in 2.620 CPU sec, 3.155 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 290637, 17, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (284, 378, 1005)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2447)
[M::mem_pestat] mean and std.dev: (523.33, 465.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3168)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 196, 301)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 631)
[M::mem_pestat] mean and std.dev: (228.10, 121.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 796)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 956, 5697)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 16725)
[M::mem_pestat] mean and std.dev: (2673.65, 2867.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 22239)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 459, 1971)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5477)
[M::mem_pestat] mean and std.dev: (1123.17, 1432.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7230)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 717830 sequences (100000040 bp) in 2.238 CPU sec, 2.309 real sec...
[M::mem_process_seqs] Processed 721430 reads in 206.092 CPU sec, 6.730 real sec
sorting block 61, #reads = 1089933 mem = 536879663 peak = 1039499264
[M::mem_process_seqs] Processed 719746 reads in 137.388 CPU sec, 4.495 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 290437, 11, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 290, 529)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1147)
[M::mem_pestat] mean and std.dev: (320.94, 202.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1456)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 197, 303)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 635)
[M::mem_pestat] mean and std.dev: (229.48, 122.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 801)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (398, 864, 865)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1799)
[M::mem_pestat] mean and std.dev: (569.22, 286.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2266)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 344, 1464)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4056)
[M::mem_pestat] mean and std.dev: (822.69, 988.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5352)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 62, #reads = 1089974 mem = 536878997 peak = 1048059904
[M::process] read 717702 sequences (100000295 bp) in 2.733 CPU sec, 3.275 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 289552, 18, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 242, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 685)
[M::mem_pestat] mean and std.dev: (235.16, 110.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 856)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 200, 305)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 639)
[M::mem_pestat] mean and std.dev: (231.07, 122.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 806)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (280, 738, 1295)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3325)
[M::mem_pestat] mean and std.dev: (969.39, 828.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4340)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 279, 969)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2495)
[M::mem_pestat] mean and std.dev: (491.00, 549.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3258)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 717770 sequences (100000241 bp) in 1.932 CPU sec, 1.943 real sec...
[M::mem_process_seqs] Processed 719168 reads in 207.637 CPU sec, 6.801 real sec
[M::mem_process_seqs] Processed 717830 reads in 138.391 CPU sec, 4.522 real sec
sorting block 63, #reads = 1086720 mem = 536881947 peak = 1048059904
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23, 289538, 15, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 296, 2308)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6582)
[M::mem_pestat] mean and std.dev: (1173.77, 1676.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8719)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 200, 306)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 642)
[M::mem_pestat] mean and std.dev: (231.87, 123.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 810)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 611, 1458)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4002)
[M::mem_pestat] mean and std.dev: (740.47, 687.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5274)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (262, 366, 625)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1351)
[M::mem_pestat] mean and std.dev: (416.30, 223.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1714)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 717436 sequences (100000090 bp) in 2.705 CPU sec, 3.254 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 289553, 12, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 377, 1457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4023)
[M::mem_pestat] mean and std.dev: (668.82, 639.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5306)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 200, 304)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 636)
[M::mem_pestat] mean and std.dev: (230.54, 121.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 802)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (619, 1799, 4791)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13135)
[M::mem_pestat] mean and std.dev: (2581.33, 2628.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17307)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (261, 347, 1041)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2601)
[M::mem_pestat] mean and std.dev: (465.14, 489.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3381)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725242 sequences (100000193 bp) in 2.059 CPU sec, 2.099 real sec...
[M::mem_process_seqs] Processed 717702 reads in 206.209 CPU sec, 6.736 real sec
[M::mem_process_seqs] Processed 717770 reads in 137.073 CPU sec, 4.470 real sec
sorting block 64, #reads = 1085376 mem = 536883964 peak = 1048059904
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 289203, 12, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (226, 606, 869)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2155)
[M::mem_pestat] mean and std.dev: (690.19, 495.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2798)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 200, 307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 645)
[M::mem_pestat] mean and std.dev: (232.26, 124.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 814)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (471, 833, 2357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6129)
[M::mem_pestat] mean and std.dev: (1412.25, 1740.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8373)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 347, 1115)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2995)
[M::mem_pestat] mean and std.dev: (514.93, 506.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3935)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 731176 sequences (100000269 bp) in 2.706 CPU sec, 3.323 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 292006, 16, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 233, 388)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 770)
[M::mem_pestat] mean and std.dev: (243.54, 126.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 961)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 187, 283)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 585)
[M::mem_pestat] mean and std.dev: (215.60, 112.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 736)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (265, 1414, 1654)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4432)
[M::mem_pestat] mean and std.dev: (1083.19, 766.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5821)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 340, 543)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1215)
[M::mem_pestat] mean and std.dev: (313.26, 169.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1551)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 731260 sequences (100000156 bp) in 2.093 CPU sec, 2.124 real sec...
[M::mem_process_seqs] Processed 717436 reads in 210.554 CPU sec, 6.919 real sec
sorting block 65, #reads = 1085404 mem = 536878973 peak = 1048059904
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 294004, 13, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 362, 577)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1433)
[M::mem_pestat] mean and std.dev: (405.10, 314.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1861)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 179, 263)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 533)
[M::mem_pestat] mean and std.dev: (202.37, 100.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 668)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (237, 920, 1376)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3654)
[M::mem_pestat] mean and std.dev: (740.27, 523.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4793)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (142, 225, 848)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2260)
[M::mem_pestat] mean and std.dev: (461.23, 491.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2966)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 727636 sequences (100000132 bp) in 2.372 CPU sec, 2.442 real sec...
[M::mem_process_seqs] Processed 731176 reads in 120.061 CPU sec, 3.822 real sec
sorting block 66, #reads = 1088326 mem = 536884664 peak = 1048059904
[M::mem_process_seqs] Processed 725242 reads in 309.816 CPU sec, 9.936 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 293812, 23, 18)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 248, 1016)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2698)
[M::mem_pestat] mean and std.dev: (498.57, 486.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3539)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 179, 263)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 533)
[M::mem_pestat] mean and std.dev: (202.48, 100.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 668)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (319, 664, 1462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3748)
[M::mem_pestat] mean and std.dev: (606.37, 499.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4891)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 304, 836)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2170)
[M::mem_pestat] mean and std.dev: (531.41, 596.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2918)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 727292 sequences (100000242 bp) in 2.784 CPU sec, 3.642 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 293382, 13, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 198, 778)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2032)
[M::mem_pestat] mean and std.dev: (281.23, 269.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2659)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 183, 273)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 559)
[M::mem_pestat] mean and std.dev: (209.72, 106.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 702)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (420, 499, 1183)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2709)
[M::mem_pestat] mean and std.dev: (594.83, 382.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3472)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 327, 637)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1499)
[M::mem_pestat] mean and std.dev: (413.81, 265.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1930)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725420 sequences (100000055 bp) in 1.945 CPU sec, 1.949 real sec...
[M::mem_process_seqs] Processed 731260 reads in 241.462 CPU sec, 7.759 real sec
sorting block 67, #reads = 1087300 mem = 536882644 peak = 1048059904
[M::mem_process_seqs] Processed 727636 reads in 143.280 CPU sec, 4.858 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (17, 293228, 16, 20)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 363, 537)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1167)
[M::mem_pestat] mean and std.dev: (294.79, 137.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1482)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 184, 276)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 568)
[M::mem_pestat] mean and std.dev: (211.30, 108.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 714)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (478, 785, 3810)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10474)
[M::mem_pestat] mean and std.dev: (1939.31, 2296.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13806)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 275, 859)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2319)
[M::mem_pestat] mean and std.dev: (393.47, 417.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3049)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 68, #reads = 1087584 mem = 536879320 peak = 1058938880
[M::process] read 724726 sequences (100000068 bp) in 2.909 CPU sec, 3.261 real sec...
[M::process] read 724198 sequences (100000004 bp) in 2.077 CPU sec, 2.079 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23, 292735, 14, 24)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 301, 638)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1494)
[M::mem_pestat] mean and std.dev: (388.95, 286.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1922)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 187, 283)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 585)
[M::mem_pestat] mean and std.dev: (215.80, 112.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 736)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (99, 448, 2338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6816)
[M::mem_pestat] mean and std.dev: (1248.93, 1581.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9055)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 347, 1228)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3308)
[M::mem_pestat] mean and std.dev: (752.67, 702.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4348)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 727292 reads in 218.530 CPU sec, 7.300 real sec
[M::mem_process_seqs] Processed 725420 reads in 142.001 CPU sec, 4.563 real sec
sorting block 69, #reads = 1088038 mem = 536876956 peak = 1058938880
[M::process] read 723392 sequences (100000257 bp) in 2.651 CPU sec, 3.050 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 292419, 11, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (144, 232, 456)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1080)
[M::mem_pestat] mean and std.dev: (282.54, 226.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1392)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 188, 286)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 592)
[M::mem_pestat] mean and std.dev: (217.99, 114.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 745)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (694, 996, 2867)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7213)
[M::mem_pestat] mean and std.dev: (1375.20, 1130.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9386)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 365, 831)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2111)
[M::mem_pestat] mean and std.dev: (526.39, 480.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2751)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723430 sequences (100000130 bp) in 2.055 CPU sec, 2.110 real sec...
[M::mem_process_seqs] Processed 724198 reads in 133.156 CPU sec, 4.265 real sec
sorting block 70, #reads = 1086817 mem = 536883363 peak = 1058938880
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 292298, 27, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 238, 580)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1376)
[M::mem_pestat] mean and std.dev: (309.53, 202.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1774)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 188, 286)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 594)
[M::mem_pestat] mean and std.dev: (217.83, 114.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 748)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 638, 1509)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4159)
[M::mem_pestat] mean and std.dev: (829.67, 693.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5484)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 293, 1080)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2944)
[M::mem_pestat] mean and std.dev: (435.07, 495.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3876)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 291947, 28, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (146, 315, 1316)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3656)
[M::mem_pestat] mean and std.dev: (508.36, 529.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4826)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 190, 289)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 601)
[M::mem_pestat] mean and std.dev: (220.03, 115.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 757)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 171, 690)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1728)
[M::mem_pestat] mean and std.dev: (361.81, 360.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2247)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 263, 707)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1759)
[M::mem_pestat] mean and std.dev: (409.47, 364.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2285)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722290 sequences (100000197 bp) in 2.110 CPU sec, 2.157 real sec...
[M::mem_process_seqs] Processed 724726 reads in 335.965 CPU sec, 10.859 real sec
[M::mem_process_seqs] Processed 723392 reads in 169.716 CPU sec, 5.589 real sec
sorting block 71, #reads = 1089492 mem = 536897043 peak = 1058938880
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 291998, 16, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 586, 1597)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4349)
[M::mem_pestat] mean and std.dev: (756.62, 766.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5725)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 190, 288)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 598)
[M::mem_pestat] mean and std.dev: (219.63, 115.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 753)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (86, 683, 824)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2300)
[M::mem_pestat] mean and std.dev: (506.00, 338.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3038)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 264, 291)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (39, 459)
[M::mem_pestat] mean and std.dev: (226.92, 72.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 543)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722528 sequences (100000193 bp) in 2.476 CPU sec, 3.066 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 290867, 20, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 313, 1205)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3243)
[M::mem_pestat] mean and std.dev: (453.54, 420.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4262)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 191, 291)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 605)
[M::mem_pestat] mean and std.dev: (221.88, 116.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 762)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (304, 799, 1219)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3049)
[M::mem_pestat] mean and std.dev: (747.75, 493.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3964)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 351, 1032)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2756)
[M::mem_pestat] mean and std.dev: (517.88, 409.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3618)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 721496 sequences (100000153 bp) in 1.850 CPU sec, 1.854 real sec...
[M::mem_process_seqs] Processed 723430 reads in 209.566 CPU sec, 6.865 real sec
[M::mem_process_seqs] Processed 722290 reads in 140.676 CPU sec, 4.617 real sec
sorting block 72, #reads = 1088599 mem = 536880104 peak = 1058938880
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 291454, 23, 19)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 371, 808)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2022)
[M::mem_pestat] mean and std.dev: (501.50, 384.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2629)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 192, 293)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 611)
[M::mem_pestat] mean and std.dev: (222.41, 117.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 770)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (466, 1161, 3841)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10591)
[M::mem_pestat] mean and std.dev: (1819.74, 2140.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13966)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (295, 337, 739)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1627)
[M::mem_pestat] mean and std.dev: (521.39, 347.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2071)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720198 sequences (100000157 bp) in 2.565 CPU sec, 3.021 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 291068, 13, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (232, 474, 1155)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3001)
[M::mem_pestat] mean and std.dev: (890.00, 882.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4418)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 193, 294)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 614)
[M::mem_pestat] mean and std.dev: (223.91, 118.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 774)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (70, 261, 1549)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4507)
[M::mem_pestat] mean and std.dev: (740.00, 949.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5986)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 336, 906)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2298)
[M::mem_pestat] mean and std.dev: (445.79, 423.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2994)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 719026 sequences (100000274 bp) in 2.062 CPU sec, 2.087 real sec...
[M::mem_process_seqs] Processed 722528 reads in 204.422 CPU sec, 6.690 real sec
sorting block 73, #reads = 1087897 mem = 536885817 peak = 1058938880
[M::mem_process_seqs] Processed 721496 reads in 137.292 CPU sec, 4.405 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 290541, 9, 21)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 381, 1943)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5389)
[M::mem_pestat] mean and std.dev: (872.68, 1004.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7112)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 196, 302)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 634)
[M::mem_pestat] mean and std.dev: (228.27, 122.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 800)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (240, 378, 1528)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4104)
[M::mem_pestat] mean and std.dev: (940.85, 1049.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5392)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 74, #reads = 1089654 mem = 536880152 peak = 1086107648
[M::process] read 719330 sequences (100000158 bp) in 2.677 CPU sec, 3.092 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 290279, 22, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (142, 188, 1014)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2758)
[M::mem_pestat] mean and std.dev: (426.34, 538.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3630)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 198, 303)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 635)
[M::mem_pestat] mean and std.dev: (229.63, 122.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 801)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 839, 1295)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3585)
[M::mem_pestat] mean and std.dev: (801.85, 723.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4730)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 414, 537)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1219)
[M::mem_pestat] mean and std.dev: (368.03, 211.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1560)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 720198 reads in 199.820 CPU sec, 6.464 real sec
[M::process] read 719418 sequences (100000112 bp) in 1.958 CPU sec, 2.037 real sec...
[M::mem_process_seqs] Processed 719026 reads in 137.037 CPU sec, 4.470 real sec
sorting block 75, #reads = 1089237 mem = 536879193 peak = 1086107648
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 289574, 30, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 440, 1118)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3004)
[M::mem_pestat] mean and std.dev: (545.71, 475.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3947)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 196, 301)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 631)
[M::mem_pestat] mean and std.dev: (228.22, 122.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 796)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (44, 571, 1008)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2936)
[M::mem_pestat] mean and std.dev: (634.52, 615.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3900)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 294, 1553)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4293)
[M::mem_pestat] mean and std.dev: (665.31, 737.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5663)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 719860 sequences (100000121 bp) in 2.613 CPU sec, 2.933 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 290004, 19, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (262, 430, 950)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2326)
[M::mem_pestat] mean and std.dev: (515.02, 405.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3014)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 196, 300)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 628)
[M::mem_pestat] mean and std.dev: (227.60, 121.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 792)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (522, 731, 1359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3033)
[M::mem_pestat] mean and std.dev: (771.83, 576.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3870)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 303, 574)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1350)
[M::mem_pestat] mean and std.dev: (382.32, 285.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1738)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722502 sequences (100000059 bp) in 2.117 CPU sec, 2.192 real sec...
[M::mem_process_seqs] Processed 719330 reads in 205.653 CPU sec, 6.690 real sec
[M::mem_process_seqs] Processed 719418 reads in 141.040 CPU sec, 4.524 real sec
sorting block 76, #reads = 1087360 mem = 536877187 peak = 1086107648
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 290373, 13, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (300, 714, 1245)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3135)
[M::mem_pestat] mean and std.dev: (642.80, 471.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4080)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 195, 296)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 616)
[M::mem_pestat] mean and std.dev: (224.85, 118.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 776)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (483, 2074, 2074)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5256)
[M::mem_pestat] mean and std.dev: (1313.38, 837.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6847)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 382, 1280)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3458)
[M::mem_pestat] mean and std.dev: (685.65, 736.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4547)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 728768 sequences (100000036 bp) in 2.911 CPU sec, 3.216 real sec...
[M::process] read 727712 sequences (100000028 bp) in 1.974 CPU sec, 1.979 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 290473, 23, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 234, 664)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1690)
[M::mem_pestat] mean and std.dev: (356.00, 407.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2203)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 190, 289)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 599)
[M::mem_pestat] mean and std.dev: (219.68, 115.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 754)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (238, 524, 1091)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2797)
[M::mem_pestat] mean and std.dev: (699.95, 737.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3650)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 355, 839)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2223)
[M::mem_pestat] mean and std.dev: (449.62, 374.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2915)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 719860 reads in 216.936 CPU sec, 7.005 real sec
sorting block 77, #reads = 1086882 mem = 536878337 peak = 1086107648
[M::mem_process_seqs] Processed 722502 reads in 157.882 CPU sec, 5.367 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 294085, 14, 23)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 331, 2395)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6859)
[M::mem_pestat] mean and std.dev: (1084.48, 1206.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9091)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 182, 272)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 558)
[M::mem_pestat] mean and std.dev: (207.94, 106.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 701)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (63, 666, 1872)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5490)
[M::mem_pestat] mean and std.dev: (975.50, 821.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7299)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 264, 457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1001)
[M::mem_pestat] mean and std.dev: (322.86, 208.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1273)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 78, #reads = 1081492 mem = 536878903 peak = 1086107648
[M::process] read 725316 sequences (100000120 bp) in 2.858 CPU sec, 3.194 real sec...
[M::process] read 724590 sequences (100000058 bp) in 1.938 CPU sec, 2.008 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 293429, 10, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 278, 993)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2611)
[M::mem_pestat] mean and std.dev: (646.73, 667.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3420)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 183, 274)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 562)
[M::mem_pestat] mean and std.dev: (209.68, 107.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 706)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (120, 1169, 1190)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3330)
[M::mem_pestat] mean and std.dev: (811.44, 626.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4400)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (245, 318, 984)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2462)
[M::mem_pestat] mean and std.dev: (584.36, 564.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3201)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 728768 reads in 204.887 CPU sec, 6.863 real sec
[M::mem_process_seqs] Processed 727712 reads in 132.945 CPU sec, 4.282 real sec
sorting block 79, #reads = 1091011 mem = 536879598 peak = 1086107648
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 292560, 22, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 292, 1217)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3349)
[M::mem_pestat] mean and std.dev: (532.70, 542.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4415)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 187, 282)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 582)
[M::mem_pestat] mean and std.dev: (215.29, 111.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 732)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (271, 568, 1497)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3949)
[M::mem_pestat] mean and std.dev: (887.32, 819.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5175)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 270, 1471)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4067)
[M::mem_pestat] mean and std.dev: (788.62, 908.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5365)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723854 sequences (100000119 bp) in 2.664 CPU sec, 3.056 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 293045, 14, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 215, 606)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1524)
[M::mem_pestat] mean and std.dev: (330.61, 291.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1983)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 188, 286)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 594)
[M::mem_pestat] mean and std.dev: (217.33, 113.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 748)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (301, 1041, 1041)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2521)
[M::mem_pestat] mean and std.dev: (803.77, 610.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3261)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 493, 898)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2354)
[M::mem_pestat] mean and std.dev: (613.45, 593.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3082)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723482 sequences (100000053 bp) in 1.952 CPU sec, 1.970 real sec...
[M::mem_process_seqs] Processed 725316 reads in 190.622 CPU sec, 6.221 real sec
[M::mem_process_seqs] Processed 724590 reads in 126.650 CPU sec, 4.154 real sec
sorting block 80, #reads = 1093291 mem = 536878968 peak = 1086107648
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 292037, 16, 23)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 421, 537)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1181)
[M::mem_pestat] mean and std.dev: (331.00, 171.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1503)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 189, 286)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 592)
[M::mem_pestat] mean and std.dev: (217.97, 113.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 745)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (557, 1155, 1913)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4625)
[M::mem_pestat] mean and std.dev: (1235.60, 1051.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5981)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (239, 573, 3072)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8738)
[M::mem_pestat] mean and std.dev: (1142.55, 1288.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11571)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722812 sequences (100000087 bp) in 2.820 CPU sec, 3.103 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 292384, 23, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 711, 2684)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7694)
[M::mem_pestat] mean and std.dev: (1280.68, 1232.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10199)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 190, 290)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 604)
[M::mem_pestat] mean and std.dev: (220.67, 116.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 761)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (360, 526, 2390)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6450)
[M::mem_pestat] mean and std.dev: (1389.96, 1427.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8480)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 273, 617)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1531)
[M::mem_pestat] mean and std.dev: (316.71, 249.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1988)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722460 sequences (100000253 bp) in 1.901 CPU sec, 1.910 real sec...
[M::mem_process_seqs] Processed 723854 reads in 195.764 CPU sec, 6.336 real sec
sorting block 81, #reads = 1094753 mem = 536878852 peak = 1086107648
[M::mem_process_seqs] Processed 723482 reads in 127.928 CPU sec, 4.103 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 292070, 13, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (123, 238, 432)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1050)
[M::mem_pestat] mean and std.dev: (276.65, 202.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1359)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 192, 293)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 611)
[M::mem_pestat] mean and std.dev: (222.74, 118.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 770)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (580, 2295, 2940)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7660)
[M::mem_pestat] mean and std.dev: (1845.54, 1600.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10020)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 233, 303)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 527)
[M::mem_pestat] mean and std.dev: (227.18, 78.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 639)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 82, #reads = 1094201 mem = 536877848 peak = 1086107648
[M::process] read 722152 sequences (100000095 bp) in 2.556 CPU sec, 2.986 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (22, 291245, 15, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (300, 503, 1295)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3285)
[M::mem_pestat] mean and std.dev: (842.95, 841.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4280)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 192, 294)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 614)
[M::mem_pestat] mean and std.dev: (223.05, 118.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 774)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (233, 544, 980)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2474)
[M::mem_pestat] mean and std.dev: (573.62, 605.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3221)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 218, 1451)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4041)
[M::mem_pestat] mean and std.dev: (669.41, 875.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5336)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 721628 sequences (100000258 bp) in 1.923 CPU sec, 1.927 real sec...
[M::mem_process_seqs] Processed 722812 reads in 199.525 CPU sec, 6.536 real sec
[M::mem_process_seqs] Processed 722460 reads in 132.568 CPU sec, 4.351 real sec
sorting block 83, #reads = 1091959 mem = 536888771 peak = 1086107648
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 291918, 17, 24)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (417, 967, 1716)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4314)
[M::mem_pestat] mean and std.dev: (906.03, 740.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5613)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 192, 294)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 614)
[M::mem_pestat] mean and std.dev: (223.42, 118.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 774)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (101, 286, 1854)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5360)
[M::mem_pestat] mean and std.dev: (959.59, 1157.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7113)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (293, 445, 710)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1544)
[M::mem_pestat] mean and std.dev: (485.59, 354.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1961)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 721416 sequences (100000140 bp) in 2.769 CPU sec, 3.052 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 291343, 23, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (243, 551, 924)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2286)
[M::mem_pestat] mean and std.dev: (632.24, 510.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2967)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 193, 296)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 620)
[M::mem_pestat] mean and std.dev: (224.58, 119.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 782)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (493, 906, 1462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3400)
[M::mem_pestat] mean and std.dev: (876.48, 564.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4369)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 342, 952)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2482)
[M::mem_pestat] mean and std.dev: (545.66, 568.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3247)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720944 sequences (100000007 bp) in 1.946 CPU sec, 1.970 real sec...
[M::mem_process_seqs] Processed 722152 reads in 200.280 CPU sec, 6.517 real sec
[M::mem_process_seqs] Processed 721628 reads in 130.970 CPU sec, 4.265 real sec
sorting block 84, #reads = 1091235 mem = 536880289 peak = 1086107648
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 290879, 14, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 339, 1253)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3443)
[M::mem_pestat] mean and std.dev: (606.97, 591.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4538)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 193, 295)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 615)
[M::mem_pestat] mean and std.dev: (224.19, 119.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 775)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (322, 866, 1677)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4387)
[M::mem_pestat] mean and std.dev: (1041.50, 984.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5742)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 394, 541)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1263)
[M::mem_pestat] mean and std.dev: (403.92, 255.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1624)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720370 sequences (100000163 bp) in 2.786 CPU sec, 3.078 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 290275, 29, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 403, 1002)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2622)
[M::mem_pestat] mean and std.dev: (437.79, 461.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3432)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 195, 298)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 624)
[M::mem_pestat] mean and std.dev: (226.25, 120.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 787)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 632, 1723)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4785)
[M::mem_pestat] mean and std.dev: (499.13, 439.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6316)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (238, 515, 1127)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2905)
[M::mem_pestat] mean and std.dev: (617.59, 471.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3794)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720408 sequences (100000051 bp) in 2.021 CPU sec, 2.031 real sec...
[M::mem_process_seqs] Processed 721416 reads in 200.668 CPU sec, 6.531 real sec
sorting block 85, #reads = 1091068 mem = 536879666 peak = 1086107648
[M::mem_process_seqs] Processed 720944 reads in 132.940 CPU sec, 4.253 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (21, 290644, 22, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (136, 236, 1063)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2917)
[M::mem_pestat] mean and std.dev: (302.72, 287.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3844)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 195, 298)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 622)
[M::mem_pestat] mean and std.dev: (226.01, 119.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 784)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (462, 764, 1193)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2655)
[M::mem_pestat] mean and std.dev: (708.20, 456.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3386)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (241, 324, 959)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2395)
[M::mem_pestat] mean and std.dev: (411.86, 399.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3113)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 86, #reads = 1088752 mem = 536879401 peak = 1086107648
[M::process] read 720460 sequences (100000048 bp) in 2.667 CPU sec, 3.037 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 290061, 19, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (247, 439, 1953)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5365)
[M::mem_pestat] mean and std.dev: (1032.47, 1152.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7071)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 196, 299)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 625)
[M::mem_pestat] mean and std.dev: (226.44, 119.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 788)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (307, 307, 687)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1447)
[M::mem_pestat] mean and std.dev: (512.61, 384.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2051)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 321, 468)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 984)
[M::mem_pestat] mean and std.dev: (298.07, 125.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1242)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720594 sequences (100000005 bp) in 2.043 CPU sec, 2.066 real sec...
[M::mem_process_seqs] Processed 720370 reads in 204.587 CPU sec, 6.718 real sec
[M::mem_process_seqs] Processed 720408 reads in 136.502 CPU sec, 4.414 real sec
sorting block 87, #reads = 1088376 mem = 536883207 peak = 1086107648
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 290077, 30, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 231, 605)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1421)
[M::mem_pestat] mean and std.dev: (325.96, 238.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1829)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 194, 296)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 616)
[M::mem_pestat] mean and std.dev: (224.81, 118.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 776)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 548, 893)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2385)
[M::mem_pestat] mean and std.dev: (623.31, 552.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3131)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 276, 408)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 846)
[M::mem_pestat] mean and std.dev: (280.38, 136.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1065)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720764 sequences (100000114 bp) in 2.564 CPU sec, 2.968 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 290381, 19, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 259, 1171)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3191)
[M::mem_pestat] mean and std.dev: (478.00, 604.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4201)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 194, 295)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 615)
[M::mem_pestat] mean and std.dev: (224.43, 118.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 775)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (258, 412, 574)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1206)
[M::mem_pestat] mean and std.dev: (362.38, 238.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1522)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 269, 419)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 857)
[M::mem_pestat] mean and std.dev: (313.21, 176.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1076)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720148 sequences (100000214 bp) in 2.037 CPU sec, 2.093 real sec...
[M::mem_process_seqs] Processed 720460 reads in 205.852 CPU sec, 6.663 real sec
sorting block 88, #reads = 1087224 mem = 536881137 peak = 1086107648
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 290563, 26, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 324, 652)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1598)
[M::mem_pestat] mean and std.dev: (375.91, 342.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2071)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 194, 295)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 615)
[M::mem_pestat] mean and std.dev: (224.31, 118.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 775)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 577, 1231)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3299)
[M::mem_pestat] mean and std.dev: (551.67, 697.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4333)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 349, 462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1008)
[M::mem_pestat] mean and std.dev: (295.78, 129.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1281)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720912 sequences (100000184 bp) in 2.398 CPU sec, 2.403 real sec...
[M::mem_process_seqs] Processed 720764 reads in 123.182 CPU sec, 3.965 real sec
[M::mem_process_seqs] Processed 720594 reads in 303.500 CPU sec, 9.781 real sec
sorting block 89, #reads = 1087763 mem = 536877142 peak = 1086107648
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 290114, 29, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 298, 647)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1571)
[M::mem_pestat] mean and std.dev: (427.20, 355.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2033)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 195, 296)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 616)
[M::mem_pestat] mean and std.dev: (225.02, 118.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 776)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (121, 528, 1005)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2773)
[M::mem_pestat] mean and std.dev: (658.21, 601.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3657)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 314, 656)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1566)
[M::mem_pestat] mean and std.dev: (379.55, 287.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2021)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 732544 sequences (100000291 bp) in 3.168 CPU sec, 3.484 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 290025, 17, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (274, 409, 3366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9550)
[M::mem_pestat] mean and std.dev: (1583.71, 1947.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12642)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 194, 294)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 612)
[M::mem_pestat] mean and std.dev: (223.59, 117.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 771)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (552, 872, 2269)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5703)
[M::mem_pestat] mean and std.dev: (1283.47, 1062.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7420)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 269, 394)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 838)
[M::mem_pestat] mean and std.dev: (257.88, 138.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1060)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 720148 reads in 234.113 CPU sec, 7.451 real sec
[M::process] read 732762 sequences (100000146 bp) in 2.298 CPU sec, 2.332 real sec...
[M::mem_process_seqs] Processed 720912 reads in 155.918 CPU sec, 4.937 real sec
sorting block 90, #reads = 1085966 mem = 536883331 peak = 1086107648
[M::process] read 730764 sequences (100000015 bp) in 3.204 CPU sec, 3.460 real sec...
[M::process] read 728336 sequences (100000093 bp) in 2.194 CPU sec, 2.197 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 294489, 7, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 248, 482)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1046)
[M::mem_pestat] mean and std.dev: (330.54, 217.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1328)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (127, 177, 260)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 526)
[M::mem_pestat] mean and std.dev: (200.03, 99.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 659)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (143, 279, 616)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1562)
[M::mem_pestat] mean and std.dev: (364.54, 296.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2035)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 732762 reads in 130.272 CPU sec, 4.129 real sec
sorting block 91, #reads = 1081184 mem = 536880463 peak = 1086107648
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23, 294184, 14, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 182, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 775)
[M::mem_pestat] mean and std.dev: (212.95, 115.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 982)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (127, 177, 260)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 526)
[M::mem_pestat] mean and std.dev: (199.89, 98.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 659)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (293, 386, 538)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1028)
[M::mem_pestat] mean and std.dev: (348.55, 113.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1273)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (264, 338, 1488)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3936)
[M::mem_pestat] mean and std.dev: (640.11, 616.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5160)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 294043, 9, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (113, 204, 351)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 827)
[M::mem_pestat] mean and std.dev: (216.10, 116.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1065)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 180, 266)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 542)
[M::mem_pestat] mean and std.dev: (204.28, 102.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 680)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 283, 479)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1067)
[M::mem_pestat] mean and std.dev: (310.70, 172.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1361)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 726626 sequences (100000057 bp) in 2.506 CPU sec, 2.540 real sec...
[M::mem_process_seqs] Processed 732544 reads in 353.316 CPU sec, 11.266 real sec
[M::mem_process_seqs] Processed 730764 reads in 180.331 CPU sec, 5.784 real sec
sorting block 92, #reads = 1086738 mem = 536885536 peak = 1090494464
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 293382, 12, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 528, 1188)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3154)
[M::mem_pestat] mean and std.dev: (651.94, 562.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4137)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 183, 273)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 561)
[M::mem_pestat] mean and std.dev: (209.48, 107.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 705)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (458, 900, 2924)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7856)
[M::mem_pestat] mean and std.dev: (1832.50, 2203.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10648)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 285, 933)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2489)
[M::mem_pestat] mean and std.dev: (526.43, 605.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3267)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725360 sequences (100000186 bp) in 2.916 CPU sec, 3.335 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 292681, 7, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 331, 802)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2008)
[M::mem_pestat] mean and std.dev: (453.79, 419.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2611)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 185, 279)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 575)
[M::mem_pestat] mean and std.dev: (213.07, 109.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 723)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 309, 389)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 739)
[M::mem_pestat] mean and std.dev: (264.71, 86.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 914)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 725064 sequences (100000042 bp) in 2.154 CPU sec, 2.215 real sec...
[M::mem_process_seqs] Processed 728336 reads in 220.933 CPU sec, 7.272 real sec
sorting block 93, #reads = 1087260 mem = 536876993 peak = 1090494464
[M::mem_process_seqs] Processed 726626 reads in 145.676 CPU sec, 4.736 real sec
sorting block 94, #reads = 1089030 mem = 536881578 peak = 1125212160
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 292529, 15, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 220, 823)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2097)
[M::mem_pestat] mean and std.dev: (481.30, 453.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2734)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 187, 283)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 585)
[M::mem_pestat] mean and std.dev: (215.96, 112.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 736)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (283, 362, 1078)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2668)
[M::mem_pestat] mean and std.dev: (566.86, 424.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3463)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 392, 1039)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2663)
[M::mem_pestat] mean and std.dev: (537.04, 456.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3475)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723746 sequences (100000064 bp) in 2.767 CPU sec, 3.265 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 292614, 18, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 305, 487)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1105)
[M::mem_pestat] mean and std.dev: (336.25, 195.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1414)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 188, 286)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 594)
[M::mem_pestat] mean and std.dev: (217.70, 114.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 748)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (270, 358, 985)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2415)
[M::mem_pestat] mean and std.dev: (417.93, 336.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3130)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 277, 404)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 900)
[M::mem_pestat] mean and std.dev: (305.24, 206.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1148)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723516 sequences (100000127 bp) in 2.076 CPU sec, 2.086 real sec...
[M::mem_process_seqs] Processed 725360 reads in 213.967 CPU sec, 6.968 real sec
[M::mem_process_seqs] Processed 725064 reads in 142.783 CPU sec, 4.675 real sec
sorting block 95, #reads = 1089593 mem = 536886584 peak = 1125212160
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20, 291736, 22, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 281, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 698)
[M::mem_pestat] mean and std.dev: (238.65, 85.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 865)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 190, 289)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 601)
[M::mem_pestat] mean and std.dev: (219.74, 115.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 757)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (31, 553, 868)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2542)
[M::mem_pestat] mean and std.dev: (396.63, 356.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3379)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 284, 690)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1654)
[M::mem_pestat] mean and std.dev: (303.24, 225.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2136)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722778 sequences (100000294 bp) in 2.660 CPU sec, 3.021 real sec...
[M::process] read 722118 sequences (100000018 bp) in 2.007 CPU sec, 2.012 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 291729, 18, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (124, 180, 430)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1042)
[M::mem_pestat] mean and std.dev: (210.33, 119.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1348)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 190, 288)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 598)
[M::mem_pestat] mean and std.dev: (219.28, 115.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 753)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (230, 563, 1144)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2972)
[M::mem_pestat] mean and std.dev: (661.56, 557.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3886)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (238, 1391, 1659)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4501)
[M::mem_pestat] mean and std.dev: (993.43, 848.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5922)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 723746 reads in 213.192 CPU sec, 6.956 real sec
[M::mem_process_seqs] Processed 723516 reads in 142.512 CPU sec, 4.633 real sec
sorting block 96, #reads = 1087596 mem = 536880570 peak = 1125212160
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 290936, 18, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (250, 362, 702)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1606)
[M::mem_pestat] mean and std.dev: (495.88, 401.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2102)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 191, 289)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 599)
[M::mem_pestat] mean and std.dev: (220.05, 115.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 754)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (312, 526, 1842)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4902)
[M::mem_pestat] mean and std.dev: (614.14, 528.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6432)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 274, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 558)
[M::mem_pestat] mean and std.dev: (247.62, 59.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 672)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722530 sequences (100000037 bp) in 2.773 CPU sec, 3.103 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 290886, 26, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 345, 1457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4001)
[M::mem_pestat] mean and std.dev: (619.61, 594.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5273)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 191, 289)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 599)
[M::mem_pestat] mean and std.dev: (220.48, 115.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 754)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (368, 540, 942)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2090)
[M::mem_pestat] mean and std.dev: (578.32, 418.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2664)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 394, 641)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1505)
[M::mem_pestat] mean and std.dev: (410.41, 292.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1937)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722384 sequences (100000096 bp) in 2.005 CPU sec, 2.007 real sec...
[M::mem_process_seqs] Processed 722778 reads in 209.127 CPU sec, 6.821 real sec
sorting block 97, #reads = 1087644 mem = 536881112 peak = 1125212160
[M::mem_process_seqs] Processed 722118 reads in 137.248 CPU sec, 4.360 real sec
sorting block 98, #reads = 1085587 mem = 536878442 peak = 1125212160
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 291145, 23, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 394, 765)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1875)
[M::mem_pestat] mean and std.dev: (455.12, 333.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2430)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 191, 290)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 602)
[M::mem_pestat] mean and std.dev: (220.67, 115.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 758)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (380, 571, 665)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1235)
[M::mem_pestat] mean and std.dev: (449.56, 156.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1520)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 241, 973)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2563)
[M::mem_pestat] mean and std.dev: (530.50, 563.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3358)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 721434 sequences (100000071 bp) in 2.787 CPU sec, 2.928 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 291276, 25, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 265, 556)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1318)
[M::mem_pestat] mean and std.dev: (355.26, 273.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1699)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 191, 289)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 599)
[M::mem_pestat] mean and std.dev: (220.33, 115.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 754)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (288, 577, 1596)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4212)
[M::mem_pestat] mean and std.dev: (905.21, 1067.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5520)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 273, 1584)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4342)
[M::mem_pestat] mean and std.dev: (774.98, 913.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5721)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 721142 sequences (100000253 bp) in 1.960 CPU sec, 1.961 real sec...
[M::mem_process_seqs] Processed 722530 reads in 194.918 CPU sec, 6.288 real sec
[M::mem_process_seqs] Processed 722384 reads in 127.854 CPU sec, 4.143 real sec
sorting block 99, #reads = 1088468 mem = 536880209 peak = 1125212160
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 291111, 17, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 345, 633)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1493)
[M::mem_pestat] mean and std.dev: (406.41, 326.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1923)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 193, 293)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 609)
[M::mem_pestat] mean and std.dev: (222.74, 117.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 767)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (300, 743, 1525)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3975)
[M::mem_pestat] mean and std.dev: (793.60, 704.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5200)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (238, 282, 451)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 877)
[M::mem_pestat] mean and std.dev: (282.09, 137.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1090)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720304 sequences (100000197 bp) in 2.646 CPU sec, 2.785 real sec...
[M::process] read 719894 sequences (100000018 bp) in 1.807 CPU sec, 1.811 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (22, 291032, 15, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (126, 258, 609)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1575)
[M::mem_pestat] mean and std.dev: (376.19, 347.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2058)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 193, 294)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 612)
[M::mem_pestat] mean and std.dev: (223.41, 117.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 771)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (132, 1424, 3378)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9870)
[M::mem_pestat] mean and std.dev: (1725.93, 1764.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13116)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (233, 353, 811)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1967)
[M::mem_pestat] mean and std.dev: (517.72, 448.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2545)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 721434 reads in 190.246 CPU sec, 6.136 real sec
[M::mem_process_seqs] Processed 721142 reads in 125.514 CPU sec, 4.068 real sec
sorting block 100, #reads = 1088576 mem = 536881647 peak = 1125212160
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 290487, 25, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (280, 620, 1961)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5323)
[M::mem_pestat] mean and std.dev: (1082.74, 1211.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7004)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 194, 295)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 615)
[M::mem_pestat] mean and std.dev: (224.13, 118.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 775)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (50, 407, 1085)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3155)
[M::mem_pestat] mean and std.dev: (590.62, 730.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4190)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 220, 562)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1364)
[M::mem_pestat] mean and std.dev: (278.00, 183.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1765)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 719560 sequences (100000029 bp) in 2.773 CPU sec, 2.895 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 290476, 19, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 219, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 628)
[M::mem_pestat] mean and std.dev: (253.62, 129.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 772)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 195, 297)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 619)
[M::mem_pestat] mean and std.dev: (225.33, 119.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 780)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (134, 499, 661)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1715)
[M::mem_pestat] mean and std.dev: (370.94, 279.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2242)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 318, 714)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1740)
[M::mem_pestat] mean and std.dev: (437.83, 321.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2253)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 456184 sequences (63311910 bp) in 1.520 CPU sec, 1.525 real sec...
[M::mem_process_seqs] Processed 720304 reads in 172.353 CPU sec, 5.561 real sec
sorting block 101, #reads = 1090930 mem = 536878211 peak = 1125212160
[M::mem_process_seqs] Processed 719894 reads in 105.506 CPU sec, 3.346 real sec
sorting block 102, #reads = 1088279 mem = 536886259 peak = 1125212160
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23, 290093, 9, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 321, 502)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1160)
[M::mem_pestat] mean and std.dev: (324.71, 165.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1489)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 196, 299)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 625)
[M::mem_pestat] mean and std.dev: (226.70, 120.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 788)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 293, 841)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2073)
[M::mem_pestat] mean and std.dev: (410.54, 352.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2689)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 719560 reads in 84.177 CPU sec, 2.925 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (13, 183767, 7, 19)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 398, 1090)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2874)
[M::mem_pestat] mean and std.dev: (394.64, 252.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3766)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 194, 296)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 618)
[M::mem_pestat] mean and std.dev: (224.71, 119.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 779)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (233, 268, 1322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3500)
[M::mem_pestat] mean and std.dev: (456.29, 490.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4589)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 456184 reads in 81.448 CPU sec, 2.722 real sec
sorting block 103, #reads = 1088890 mem = 536882265 peak = 1125212160
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000a06d1
  features: bfebfbff 7ffefbff
  extended: f3bfb7ef fb417ffe
  amd bits: 2c100800 00000121
     brand: Intel(R) Xeon(R) 6975P-C
threads: 31
algo: bwa-mem
license: sentieon:klib=31
reads: 112983286
overall: 70168666112 mem 18487.800 user 403.913 sys 628.409 real
[main] Version: 0.7.17-r1188
[main] CMD: /opt/conda/share/sentieon-202308.03-3/libexec/bwa mem -K 100000000 -Y -R @RG\tID:A23MHWWLT4.1136_8DV-T1-TDNA-1_A23MHWWLT4_1.L003\tPU:L003\tSM:1136_8DV-T1-TDNA-1_A23MHWWLT4_1\tLB:1136_8DV-T1-TDNA-1_A23MHWWLT4_1\tDS:s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta\tPL:ILLUMINA -t 31 ./BWAIndex/Homo_sapiens_assembly38.fasta.64 1136_8DV-T1-TDNA-1_A23MHWWLT4_1_R1.fastq.gz 1136_8DV-T1-TDNA-1_A23MHWWLT4_1_R2.fastq.gz
[main] Real time: 628.452 sec; CPU: 18891.716 sec
sorting block 104, #reads = 433102 mem = 214279263 peak = 1125212160
uniq header count 1
merging 105 blocks
sw version: sentieon-genomics-202308.03
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000a06d1
  features: bfebfbff 7ffefbff
  extended: f3bfb7ef fb417ffe
  amd bits: 2c100800 00000121
     brand: Intel(R) Xeon(R) 6975P-C
threads: 31 max 192
algo: util-sort
license: sentieon:util=1
output file size: 6200101749
output reads: 113816100
bam_mem_sort: 105 calls 70.819 user 1.696 sys 75.314 real
bam_write: 105 calls 64.048 user 4.111 sys 136.037 real
execute: 1 calls 34.070 user 1.811 sys 668.397 real
merge_files: 1 calls 34.041 user 1.796 sys 39.621 real
parse_chunk: 1671 calls 77.441 user 18.685 sys 122.533 real
read_chunk: 4529 calls 40.942 user 23.332 sys 573.810 real
sort_block: 1 calls 26.590 user 22.698 sys 554.413 real
write_chunk: 2856 calls 33.666 user 1.572 sys 38.719 real
overall: 3421106176 mem 1559.645 user 66.973 sys 668.419 real
ls: cannot access '*.cram': No such file or directory