Downloading: s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/cd/e6171b47df25da081865b24d406cee/.command.sh
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/4c/a448c4993795e870a5cd9b9a1c3170/1029_IWL-T1-TDNA-1_A23MHWWLT4_1/1029_IWL-T1-TDNA-1_A23MHWWLT4_1_R2.fastq.gz
  Downloading: s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta.fai
  Downloading: s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/BWAIndex
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/cd/e6171b47df25da081865b24d406cee/.command.run
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/4c/a448c4993795e870a5cd9b9a1c3170/1029_IWL-T1-TDNA-1_A23MHWWLT4_1/1029_IWL-T1-TDNA-1_A23MHWWLT4_1_R1.fastq.gz
==> STAGING COMPLETE (7 inputs)

This software is licensed to bgold@natera.com by Sentieon Inc.
cmdline: /opt/conda/share/sentieon-202308.03-3/libexec/util sort -r Homo_sapiens_assembly38.fasta -t 31 -o 1029_IWL-T1-TDNA-1_A23MHWWLT4_1.bam --sam2bam -
This software is licensed to bgold@natera.com by Sentieon Inc.
version: sentieon-genomics-202308.03
[M::bwa_idx_load_from_disk] read 3171 ALT contigs
[M::main_mem] bwa index loaded in 1853.946 CPU sec, 67.420 real sec
[M::process] read 771304 sequences (100000192 bp) in 1.104 CPU sec, 1.121 real sec...
[M::process] read 769066 sequences (100000213 bp) in 1.472 CPU sec, 1.556 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (13, 304944, 6, 17)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 360, 850)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2246)
[M::mem_pestat] mean and std.dev: (417.58, 348.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2944)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 374)
[M::mem_pestat] mean and std.dev: (158.75, 64.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 462)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 175, 463)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1119)
[M::mem_pestat] mean and std.dev: (246.93, 157.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1447)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 767658 sequences (100000273 bp) in 1.605 CPU sec, 1.714 real sec...
[M::process] read 767236 sequences (100000159 bp) in 1.539 CPU sec, 1.604 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (18, 304405, 6, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (139, 225, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 802)
[M::mem_pestat] mean and std.dev: (226.35, 115.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1023)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 381)
[M::mem_pestat] mean and std.dev: (160.63, 66.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 471)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 255, 1329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3685)
[M::mem_pestat] mean and std.dev: (490.16, 492.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4863)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 771304 reads in 207.359 CPU sec, 6.791 real sec
[M::mem_process_seqs] Processed 769066 reads in 138.162 CPU sec, 4.536 real sec
sorting block 0, #reads = 1113894 mem = 536884261 peak = 582172672
[M::process] read 766166 sequences (100000066 bp) in 2.133 CPU sec, 2.214 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (12, 303700, 7, 17)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 345, 556)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1278)
[M::mem_pestat] mean and std.dev: (377.27, 271.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1639)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 149, 203)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 387)
[M::mem_pestat] mean and std.dev: (161.83, 67.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 479)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 233, 783)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1959)
[M::mem_pestat] mean and std.dev: (431.00, 390.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2547)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 766280 sequences (100000098 bp) in 1.620 CPU sec, 1.615 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (11, 304023, 11, 16)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 250, 792)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2082)
[M::mem_pestat] mean and std.dev: (311.56, 246.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2727)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (112, 149, 203)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 385)
[M::mem_pestat] mean and std.dev: (161.95, 67.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 476)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (243, 540, 1069)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2721)
[M::mem_pestat] mean and std.dev: (528.44, 392.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3547)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 145, 286)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 590)
[M::mem_pestat] mean and std.dev: (165.46, 67.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 742)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 767658 reads in 203.325 CPU sec, 6.505 real sec
sorting block 1, #reads = 1110160 mem = 536882447 peak = 766197760
[M::mem_process_seqs] Processed 767236 reads in 233.276 CPU sec, 7.499 real sec
[M::process] read 764688 sequences (100000200 bp) in 2.015 CPU sec, 2.086 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (19, 303002, 10, 13)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (109, 187, 594)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1564)
[M::mem_pestat] mean and std.dev: (449.74, 496.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2437)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (112, 149, 204)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 388)
[M::mem_pestat] mean and std.dev: (162.62, 67.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 480)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (95, 160, 327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 791)
[M::mem_pestat] mean and std.dev: (213.00, 178.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1023)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 194, 1307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3579)
[M::mem_pestat] mean and std.dev: (494.85, 494.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4715)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 764574 sequences (100000199 bp) in 1.735 CPU sec, 1.756 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (12, 302784, 9, 14)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 286, 2072)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5898)
[M::mem_pestat] mean and std.dev: (764.55, 858.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7811)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (112, 150, 205)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 391)
[M::mem_pestat] mean and std.dev: (163.71, 68.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 484)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 240, 1443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3999)
[M::mem_pestat] mean and std.dev: (674.86, 695.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5277)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (17, 303937, 11, 17)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 236, 743)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1845)
[M::mem_pestat] mean and std.dev: (337.07, 257.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2396)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (112, 149, 204)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 388)
[M::mem_pestat] mean and std.dev: (162.60, 68.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 480)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (547, 614, 628)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (385, 790)
[M::mem_pestat] mean and std.dev: (598.67, 36.87)
[M::mem_pestat] low and high boundaries for proper pairs: (304, 871)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 190, 1086)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2952)
[M::mem_pestat] mean and std.dev: (370.27, 404.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3885)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 766166 reads in 292.737 CPU sec, 9.525 real sec
sorting block 2, #reads = 1111030 mem = 536888367 peak = 795402240
[M::mem_process_seqs] Processed 764688 reads in 227.130 CPU sec, 7.474 real sec
[M::mem_process_seqs] Processed 766280 reads in 246.185 CPU sec, 8.102 real sec
sorting block 3, #reads = 1108952 mem = 536875680 peak = 804122624
[M::process] read 763122 sequences (100000156 bp) in 2.538 CPU sec, 2.656 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 302801, 6, 11)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (140, 222, 931)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2513)
[M::mem_pestat] mean and std.dev: (529.50, 550.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3304)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (112, 151, 205)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 391)
[M::mem_pestat] mean and std.dev: (163.65, 68.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 484)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (451, 805, 1647)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4039)
[M::mem_pestat] mean and std.dev: (1079.82, 979.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5235)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 762384 sequences (100000027 bp) in 2.377 CPU sec, 2.440 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (13, 301915, 12, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (99, 152, 227)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 483)
[M::mem_pestat] mean and std.dev: (144.73, 44.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 611)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (113, 151, 206)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 392)
[M::mem_pestat] mean and std.dev: (164.47, 69.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 485)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (126, 335, 825)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2223)
[M::mem_pestat] mean and std.dev: (419.58, 399.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2922)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 432, 639)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1461)
[M::mem_pestat] mean and std.dev: (406.19, 237.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1872)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 764574 reads in 204.149 CPU sec, 6.494 real sec
[M::process] read 762536 sequences (100000143 bp) in 1.830 CPU sec, 1.835 real sec...
sorting block 4, #reads = 1110685 mem = 536877081 peak = 804122624
[M::mem_process_seqs] Processed 763122 reads in 135.130 CPU sec, 4.279 real sec
sorting block 5, #reads = 1107922 mem = 536881923 peak = 879001600
[M::process] read 763730 sequences (100000195 bp) in 2.347 CPU sec, 2.741 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (11, 302103, 2, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 170, 463)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1095)
[M::mem_pestat] mean and std.dev: (284.80, 268.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1411)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (113, 152, 207)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 395)
[M::mem_pestat] mean and std.dev: (165.35, 69.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 489)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 161, 594)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1522)
[M::mem_pestat] mean and std.dev: (280.63, 243.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1986)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 762936 sequences (100000024 bp) in 1.918 CPU sec, 1.927 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (19, 302055, 11, 23)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (374, 561, 887)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1913)
[M::mem_pestat] mean and std.dev: (477.12, 242.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2426)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (113, 152, 207)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 395)
[M::mem_pestat] mean and std.dev: (165.17, 69.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 489)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (733, 749, 1662)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3520)
[M::mem_pestat] mean and std.dev: (1028.82, 597.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4449)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 350, 706)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1706)
[M::mem_pestat] mean and std.dev: (339.74, 213.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2206)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 762384 reads in 193.456 CPU sec, 6.143 real sec
[M::mem_process_seqs] Processed 762536 reads in 130.861 CPU sec, 4.174 real sec
sorting block 6, #reads = 1108002 mem = 536884808 peak = 879001600
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (13, 302628, 6, 22)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 352, 1785)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5055)
[M::mem_pestat] mean and std.dev: (813.08, 968.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6690)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (113, 151, 206)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 392)
[M::mem_pestat] mean and std.dev: (164.44, 68.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 485)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 497, 1164)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3124)
[M::mem_pestat] mean and std.dev: (651.85, 570.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4104)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 762430 sequences (100000230 bp) in 2.465 CPU sec, 2.578 real sec...
[M::process] read 768884 sequences (100000177 bp) in 2.050 CPU sec, 2.050 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 302489, 6, 15)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 373, 1337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3701)
[M::mem_pestat] mean and std.dev: (608.15, 647.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4883)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (113, 151, 207)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 395)
[M::mem_pestat] mean and std.dev: (164.84, 69.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 489)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 290, 495)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1137)
[M::mem_pestat] mean and std.dev: (267.85, 130.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1458)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 763730 reads in 200.181 CPU sec, 6.366 real sec
sorting block 7, #reads = 1106921 mem = 536880245 peak = 879001600
[M::mem_process_seqs] Processed 762936 reads in 136.633 CPU sec, 4.360 real sec
sorting block 8, #reads = 1105243 mem = 536885718 peak = 879001600
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (14, 301952, 11, 13)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 240, 2069)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5829)
[M::mem_pestat] mean and std.dev: (688.17, 999.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7709)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (113, 152, 208)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 398)
[M::mem_pestat] mean and std.dev: (165.69, 70.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 493)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 173, 2349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6725)
[M::mem_pestat] mean and std.dev: (1179.73, 1413.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8913)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 271, 657)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1701)
[M::mem_pestat] mean and std.dev: (390.69, 340.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2223)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 768960 sequences (100000254 bp) in 2.871 CPU sec, 2.976 real sec...
[M::process] read 767868 sequences (100000179 bp) in 1.767 CPU sec, 1.764 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (14, 303836, 6, 16)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (143, 201, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 704)
[M::mem_pestat] mean and std.dev: (185.82, 72.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 891)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 381)
[M::mem_pestat] mean and std.dev: (160.79, 66.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 471)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 392, 938)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2510)
[M::mem_pestat] mean and std.dev: (630.81, 651.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3296)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 762430 reads in 201.937 CPU sec, 6.422 real sec
[M::mem_process_seqs] Processed 768884 reads in 136.739 CPU sec, 4.370 real sec
sorting block 9, #reads = 1102746 mem = 536877072 peak = 879001600
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (15, 304240, 15, 8)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (135, 170, 378)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 864)
[M::mem_pestat] mean and std.dev: (176.92, 79.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1107)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 381)
[M::mem_pestat] mean and std.dev: (160.40, 66.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 471)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (415, 644, 830)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1660)
[M::mem_pestat] mean and std.dev: (589.29, 354.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2075)
[M::mem_pestat] skip orientation RR as there are not enough pairs
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::process] read 767728 sequences (100000065 bp) in 2.789 CPU sec, 2.938 real sec...
[M::process] read 766522 sequences (100000092 bp) in 1.729 CPU sec, 1.732 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (22, 304339, 6, 19)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (121, 169, 738)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1972)
[M::mem_pestat] mean and std.dev: (370.45, 354.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2589)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 384)
[M::mem_pestat] mean and std.dev: (161.35, 67.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 475)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 161, 1488)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4162)
[M::mem_pestat] mean and std.dev: (429.12, 637.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5499)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 768960 reads in 194.024 CPU sec, 6.183 real sec
[M::mem_process_seqs] Processed 767868 reads in 131.626 CPU sec, 4.191 real sec
sorting block 10, #reads = 1112629 mem = 536880961 peak = 879001600
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (17, 304491, 5, 15)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 304, 1179)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3167)
[M::mem_pestat] mean and std.dev: (670.69, 627.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4161)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 149, 202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 384)
[M::mem_pestat] mean and std.dev: (161.65, 67.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 475)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 687, 932)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2490)
[M::mem_pestat] mean and std.dev: (554.77, 469.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3269)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 766092 sequences (100000283 bp) in 2.666 CPU sec, 2.750 real sec...
[M::process] read 765922 sequences (100000301 bp) in 2.140 CPU sec, 2.138 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20, 303609, 15, 13)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (120, 226, 609)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1587)
[M::mem_pestat] mean and std.dev: (341.21, 322.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2076)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (112, 149, 203)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 385)
[M::mem_pestat] mean and std.dev: (162.29, 67.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 476)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 444, 1403)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3909)
[M::mem_pestat] mean and std.dev: (636.57, 528.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5162)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 211, 440)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1006)
[M::mem_pestat] mean and std.dev: (245.58, 148.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1289)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 767728 reads in 199.203 CPU sec, 6.333 real sec
sorting block 11, #reads = 1113602 mem = 536883096 peak = 879001600
[M::mem_process_seqs] Processed 766522 reads in 133.886 CPU sec, 4.257 real sec
sorting block 12, #reads = 1111588 mem = 536882687 peak = 888299520
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (21, 303802, 11, 12)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (111, 151, 952)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2634)
[M::mem_pestat] mean and std.dev: (617.29, 819.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3895)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (112, 150, 204)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 388)
[M::mem_pestat] mean and std.dev: (162.83, 68.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 480)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (726, 1150, 3847)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10089)
[M::mem_pestat] mean and std.dev: (1788.36, 1448.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13210)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 160, 223)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 405)
[M::mem_pestat] mean and std.dev: (162.18, 43.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 496)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 764678 sequences (100000288 bp) in 2.592 CPU sec, 2.671 real sec...
[M::process] read 763264 sequences (100000183 bp) in 1.929 CPU sec, 1.937 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (15, 303687, 7, 23)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (363, 954, 2579)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7011)
[M::mem_pestat] mean and std.dev: (1448.00, 1315.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9227)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (112, 150, 204)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 388)
[M::mem_pestat] mean and std.dev: (162.53, 67.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 480)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 380, 1445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3907)
[M::mem_pestat] mean and std.dev: (571.67, 496.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5138)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 766092 reads in 191.307 CPU sec, 6.082 real sec
[M::mem_process_seqs] Processed 765922 reads in 128.929 CPU sec, 4.099 real sec
sorting block 13, #reads = 1111262 mem = 536880658 peak = 888299520
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23, 303022, 10, 14)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (280, 344, 1489)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3907)
[M::mem_pestat] mean and std.dev: (699.57, 650.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5116)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (112, 151, 205)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 391)
[M::mem_pestat] mean and std.dev: (163.77, 68.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 484)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (84, 260, 369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 939)
[M::mem_pestat] mean and std.dev: (247.10, 182.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1224)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 263, 2807)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8081)
[M::mem_pestat] mean and std.dev: (1025.50, 1334.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10718)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 762644 sequences (100000136 bp) in 3.070 CPU sec, 3.182 real sec...
[M::process] read 762172 sequences (100000031 bp) in 1.999 CPU sec, 2.004 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (19, 302872, 5, 13)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (137, 211, 682)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1772)
[M::mem_pestat] mean and std.dev: (311.56, 291.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2317)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (113, 151, 207)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 395)
[M::mem_pestat] mean and std.dev: (164.99, 69.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 489)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 390, 662)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1614)
[M::mem_pestat] mean and std.dev: (357.54, 205.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2090)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 764678 reads in 193.375 CPU sec, 6.132 real sec
sorting block 14, #reads = 1111468 mem = 536882797 peak = 888299520
[M::mem_process_seqs] Processed 763264 reads in 130.943 CPU sec, 4.160 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (13, 302253, 10, 13)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 201, 592)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1480)
[M::mem_pestat] mean and std.dev: (294.00, 203.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1924)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (113, 152, 207)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 395)
[M::mem_pestat] mean and std.dev: (165.09, 69.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 489)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 761, 1042)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2818)
[M::mem_pestat] mean and std.dev: (649.33, 590.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3706)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 481, 1059)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2857)
[M::mem_pestat] mean and std.dev: (569.17, 454.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3756)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 763148 sequences (100000058 bp) in 2.517 CPU sec, 2.600 real sec...
[M::process] read 763730 sequences (100000230 bp) in 1.609 CPU sec, 1.601 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20, 301851, 5, 18)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 236, 835)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2169)
[M::mem_pestat] mean and std.dev: (504.40, 505.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2836)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (113, 152, 207)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 395)
[M::mem_pestat] mean and std.dev: (165.40, 69.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 489)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (126, 310, 944)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2580)
[M::mem_pestat] mean and std.dev: (364.80, 347.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3398)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 762644 reads in 191.418 CPU sec, 6.099 real sec
sorting block 15, #reads = 1109378 mem = 536878226 peak = 888299520
[M::mem_process_seqs] Processed 762172 reads in 131.456 CPU sec, 4.193 real sec
sorting block 16, #reads = 1107478 mem = 536878510 peak = 888299520
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 302038, 4, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 249, 801)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2101)
[M::mem_pestat] mean and std.dev: (442.42, 416.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2751)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (113, 151, 207)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 395)
[M::mem_pestat] mean and std.dev: (164.82, 69.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 489)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 331, 1037)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2841)
[M::mem_pestat] mean and std.dev: (627.89, 638.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3743)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 764150 sequences (100000135 bp) in 2.669 CPU sec, 2.740 real sec...
[M::process] read 767180 sequences (100000180 bp) in 1.740 CPU sec, 1.740 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 302503, 16, 11)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 416, 629)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1567)
[M::mem_pestat] mean and std.dev: (383.69, 219.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2036)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (113, 151, 206)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 392)
[M::mem_pestat] mean and std.dev: (164.27, 68.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 485)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 284, 1403)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3823)
[M::mem_pestat] mean and std.dev: (592.36, 826.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5033)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (139, 157, 391)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 895)
[M::mem_pestat] mean and std.dev: (267.45, 205.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1147)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 763148 reads in 195.883 CPU sec, 6.235 real sec
[M::mem_process_seqs] Processed 763730 reads in 133.073 CPU sec, 4.241 real sec
sorting block 17, #reads = 1105607 mem = 536878165 peak = 888299520
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (11, 302066, 9, 15)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 208, 458)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1050)
[M::mem_pestat] mean and std.dev: (347.18, 261.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1392)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (113, 151, 206)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 392)
[M::mem_pestat] mean and std.dev: (164.17, 69.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 485)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 303, 1014)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2728)
[M::mem_pestat] mean and std.dev: (559.53, 525.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3585)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 770768 sequences (100000022 bp) in 2.451 CPU sec, 2.534 real sec...
[M::process] read 770726 sequences (100000190 bp) in 1.639 CPU sec, 1.636 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (12, 303222, 3, 17)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (89, 165, 448)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1166)
[M::mem_pestat] mean and std.dev: (325.33, 338.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1680)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 149, 203)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 387)
[M::mem_pestat] mean and std.dev: (161.93, 67.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 479)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 366, 777)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1975)
[M::mem_pestat] mean and std.dev: (412.25, 256.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2574)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 764150 reads in 201.787 CPU sec, 6.438 real sec
sorting block 18, #reads = 1107800 mem = 536876979 peak = 888299520
[M::mem_process_seqs] Processed 767180 reads in 136.559 CPU sec, 4.364 real sec
sorting block 19, #reads = 1104997 mem = 536879633 peak = 890691584
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20, 304785, 7, 11)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (144, 195, 290)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 582)
[M::mem_pestat] mean and std.dev: (226.00, 121.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 728)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 377)
[M::mem_pestat] mean and std.dev: (159.26, 65.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 466)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (420, 1274, 1497)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3651)
[M::mem_pestat] mean and std.dev: (1081.40, 1000.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5084)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 769466 sequences (100000150 bp) in 2.744 CPU sec, 2.815 real sec...
[M::process] read 768286 sequences (100000275 bp) in 1.600 CPU sec, 1.603 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (12, 305279, 9, 13)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (124, 155, 936)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2560)
[M::mem_pestat] mean and std.dev: (297.55, 343.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3372)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 377)
[M::mem_pestat] mean and std.dev: (159.30, 65.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 466)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 260, 2778)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8076)
[M::mem_pestat] mean and std.dev: (1155.54, 1584.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10725)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 770768 reads in 183.577 CPU sec, 5.837 real sec
[M::mem_process_seqs] Processed 770726 reads in 123.994 CPU sec, 3.958 real sec
sorting block 20, #reads = 1113493 mem = 536879909 peak = 890691584
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (17, 304682, 12, 19)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 219, 549)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1349)
[M::mem_pestat] mean and std.dev: (239.00, 135.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1749)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 147, 200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 378)
[M::mem_pestat] mean and std.dev: (159.93, 65.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 467)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 525, 1302)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3606)
[M::mem_pestat] mean and std.dev: (422.40, 392.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4758)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 240, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 629)
[M::mem_pestat] mean and std.dev: (246.88, 110.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 776)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 767186 sequences (100000231 bp) in 2.547 CPU sec, 2.610 real sec...
[M::process] read 767132 sequences (100000199 bp) in 1.990 CPU sec, 1.982 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (10, 304771, 10, 7)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 660, 3189)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9273)
[M::mem_pestat] mean and std.dev: (1777.70, 2269.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12315)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 381)
[M::mem_pestat] mean and std.dev: (160.80, 66.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 471)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (368, 596, 910)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1994)
[M::mem_pestat] mean and std.dev: (729.20, 554.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2948)
[M::mem_pestat] skip orientation RR as there are not enough pairs
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_process_seqs] Processed 769466 reads in 186.305 CPU sec, 5.921 real sec
sorting block 21, #reads = 1113059 mem = 536882630 peak = 890691584
[M::mem_process_seqs] Processed 768286 reads in 124.930 CPU sec, 3.968 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (14, 304134, 5, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (138, 231, 763)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2013)
[M::mem_pestat] mean and std.dev: (448.31, 412.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2638)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 149, 203)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 387)
[M::mem_pestat] mean and std.dev: (161.85, 67.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 479)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 366, 1510)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4204)
[M::mem_pestat] mean and std.dev: (549.09, 507.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5551)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 766650 sequences (100000126 bp) in 2.442 CPU sec, 2.533 real sec...
[M::process] read 765776 sequences (100000223 bp) in 1.560 CPU sec, 1.566 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (15, 303791, 9, 13)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (145, 734, 1198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3304)
[M::mem_pestat] mean and std.dev: (642.85, 703.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4357)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 149, 203)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 387)
[M::mem_pestat] mean and std.dev: (161.94, 67.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 479)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 178, 402)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 910)
[M::mem_pestat] mean and std.dev: (233.42, 129.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1164)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 767186 reads in 185.940 CPU sec, 5.926 real sec
sorting block 22, #reads = 1112676 mem = 536878808 peak = 890691584
[M::mem_process_seqs] Processed 767132 reads in 127.090 CPU sec, 4.061 real sec
sorting block 23, #reads = 1112727 mem = 536884126 peak = 928423936
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (8, 303959, 10, 16)
[M::mem_pestat] skip orientation FF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (112, 149, 203)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 385)
[M::mem_pestat] mean and std.dev: (162.12, 67.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 476)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (441, 3808, 6173)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 17637)
[M::mem_pestat] mean and std.dev: (3370.30, 2788.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 23369)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (140, 222, 818)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2174)
[M::mem_pestat] mean and std.dev: (414.69, 379.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2852)
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 765938 sequences (100000191 bp) in 2.276 CPU sec, 2.344 real sec...
[M::process] read 764892 sequences (100000289 bp) in 1.830 CPU sec, 1.824 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (18, 303562, 12, 14)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (125, 554, 1374)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3872)
[M::mem_pestat] mean and std.dev: (861.33, 918.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5121)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (112, 150, 204)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 388)
[M::mem_pestat] mean and std.dev: (162.62, 67.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 480)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (296, 1195, 1195)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2993)
[M::mem_pestat] mean and std.dev: (831.27, 678.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3892)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (103, 210, 408)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1018)
[M::mem_pestat] mean and std.dev: (247.67, 222.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1323)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 766650 reads in 180.523 CPU sec, 5.745 real sec
[M::mem_process_seqs] Processed 765776 reads in 121.540 CPU sec, 3.864 real sec
sorting block 24, #reads = 1111622 mem = 536879422 peak = 928423936
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (19, 303339, 4, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 296, 713)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1701)
[M::mem_pestat] mean and std.dev: (354.94, 224.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2195)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (112, 150, 204)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 388)
[M::mem_pestat] mean and std.dev: (162.79, 68.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 480)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 290, 1279)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3513)
[M::mem_pestat] mean and std.dev: (590.27, 724.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4630)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 763886 sequences (100000131 bp) in 2.726 CPU sec, 2.819 real sec...
[M::process] read 764068 sequences (100000124 bp) in 1.910 CPU sec, 1.915 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 303249, 7, 14)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 448, 652)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1592)
[M::mem_pestat] mean and std.dev: (391.60, 290.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2062)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (112, 150, 206)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 394)
[M::mem_pestat] mean and std.dev: (164.12, 69.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 488)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 209, 394)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 872)
[M::mem_pestat] mean and std.dev: (199.18, 87.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1111)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 765938 reads in 192.119 CPU sec, 6.114 real sec
sorting block 25, #reads = 1111272 mem = 536883537 peak = 928423936
[M::mem_process_seqs] Processed 764892 reads in 125.742 CPU sec, 4.008 real sec
sorting block 26, #reads = 1110925 mem = 536878163 peak = 928423936
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (14, 302970, 12, 18)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (138, 433, 453)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1083)
[M::mem_pestat] mean and std.dev: (333.00, 224.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1398)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (113, 151, 206)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 392)
[M::mem_pestat] mean and std.dev: (164.24, 69.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 485)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (422, 1044, 2836)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7664)
[M::mem_pestat] mean and std.dev: (1344.42, 1103.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10078)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 265, 466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1076)
[M::mem_pestat] mean and std.dev: (248.67, 117.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1381)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 764290 sequences (100000169 bp) in 2.322 CPU sec, 2.375 real sec...
[M::process] read 764548 sequences (100000008 bp) in 1.680 CPU sec, 1.683 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 302787, 2, 21)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (230, 488, 2390)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6710)
[M::mem_pestat] mean and std.dev: (1041.56, 1192.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8870)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (113, 151, 206)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 392)
[M::mem_pestat] mean and std.dev: (164.29, 69.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 485)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (241, 394, 1734)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4720)
[M::mem_pestat] mean and std.dev: (931.14, 1083.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6213)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 763886 reads in 193.789 CPU sec, 6.179 real sec
[M::mem_process_seqs] Processed 764068 reads in 134.163 CPU sec, 4.283 real sec
sorting block 27, #reads = 1106342 mem = 536878870 peak = 928423936
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (22, 302552, 15, 12)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 541, 1325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3671)
[M::mem_pestat] mean and std.dev: (716.50, 624.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4844)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (112, 151, 205)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 391)
[M::mem_pestat] mean and std.dev: (163.75, 68.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 484)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (393, 456, 1821)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4677)
[M::mem_pestat] mean and std.dev: (645.58, 571.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6105)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 451, 771)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2011)
[M::mem_pestat] mean and std.dev: (519.92, 516.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2631)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 771112 sequences (100000180 bp) in 2.890 CPU sec, 2.964 real sec...
[M::process] read 769356 sequences (100000213 bp) in 1.959 CPU sec, 1.961 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (17, 302767, 4, 12)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (137, 284, 1246)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3464)
[M::mem_pestat] mean and std.dev: (507.71, 468.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4573)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (112, 150, 205)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 391)
[M::mem_pestat] mean and std.dev: (163.45, 68.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 484)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 845, 2026)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5764)
[M::mem_pestat] mean and std.dev: (1267.42, 1410.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7633)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 764290 reads in 194.916 CPU sec, 6.187 real sec
sorting block 28, #reads = 1106897 mem = 536881069 peak = 928423936
[M::mem_process_seqs] Processed 764548 reads in 131.829 CPU sec, 4.191 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (21, 305147, 14, 16)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 229, 1021)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2769)
[M::mem_pestat] mean and std.dev: (481.05, 543.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3643)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 377)
[M::mem_pestat] mean and std.dev: (159.05, 65.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 466)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1129, 1684, 2443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5071)
[M::mem_pestat] mean and std.dev: (1932.36, 1335.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7273)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 263, 409)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 739)
[M::mem_pestat] mean and std.dev: (255.93, 82.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 904)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 769604 sequences (100000124 bp) in 3.150 CPU sec, 3.272 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (14, 304693, 7, 15)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 251, 584)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1432)
[M::mem_pestat] mean and std.dev: (318.50, 248.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1856)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 378)
[M::mem_pestat] mean and std.dev: (160.07, 65.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 467)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 170, 236)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 438)
[M::mem_pestat] mean and std.dev: (172.46, 55.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 539)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 769018 sequences (100000216 bp) in 2.038 CPU sec, 2.039 real sec...
[M::mem_process_seqs] Processed 771112 reads in 193.932 CPU sec, 6.153 real sec
sorting block 29, #reads = 1106864 mem = 536879617 peak = 928423936
[M::mem_process_seqs] Processed 769356 reads in 134.186 CPU sec, 4.263 real sec
sorting block 30, #reads = 1114256 mem = 536883408 peak = 989396992
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (12, 304852, 2, 17)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (139, 183, 1251)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3475)
[M::mem_pestat] mean and std.dev: (480.45, 708.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4587)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 147, 200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 378)
[M::mem_pestat] mean and std.dev: (159.83, 65.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 467)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 629, 975)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2545)
[M::mem_pestat] mean and std.dev: (665.88, 601.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3330)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 768664 sequences (100000036 bp) in 3.062 CPU sec, 3.133 real sec...
[M::process] read 767740 sequences (100000043 bp) in 2.033 CPU sec, 2.041 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (17, 304442, 8, 11)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 248, 1130)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3090)
[M::mem_pestat] mean and std.dev: (434.75, 411.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4070)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 381)
[M::mem_pestat] mean and std.dev: (160.69, 66.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 471)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 219, 259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 441)
[M::mem_pestat] mean and std.dev: (187.44, 59.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 532)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 769604 reads in 196.991 CPU sec, 6.256 real sec
[M::process] read 767450 sequences (100000217 bp) in 2.350 CPU sec, 2.360 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 303976, 2, 15)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 669, 5684)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 16738)
[M::mem_pestat] mean and std.dev: (2145.81, 2563.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 22265)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 149, 203)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 387)
[M::mem_pestat] mean and std.dev: (161.82, 67.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 479)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 469, 1384)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3796)
[M::mem_pestat] mean and std.dev: (625.64, 655.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5002)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 767740 reads in 106.086 CPU sec, 3.485 real sec
sorting block 31, #reads = 1114426 mem = 536878077 peak = 989396992
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 304696, 6, 6)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 427, 1208)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3312)
[M::mem_pestat] mean and std.dev: (620.82, 644.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4364)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 381)
[M::mem_pestat] mean and std.dev: (160.66, 66.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 471)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] skip orientation RR as there are not enough pairs
[M::mem_pestat] skip orientation FF
[M::mem_process_seqs] Processed 768664 reads in 217.016 CPU sec, 7.825 real sec
sorting block 32, #reads = 1113008 mem = 536878874 peak = 1023025152
[M::mem_process_seqs] Processed 769018 reads in 410.670 CPU sec, 13.968 real sec
[M::process] read 766820 sequences (100000227 bp) in 2.638 CPU sec, 2.709 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (22, 303531, 11, 22)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 358, 1237)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3375)
[M::mem_pestat] mean and std.dev: (666.36, 708.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4444)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 149, 202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 384)
[M::mem_pestat] mean and std.dev: (161.54, 67.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 475)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (19, 480, 525)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1537)
[M::mem_pestat] mean and std.dev: (391.09, 413.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2044)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 372, 1919)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5403)
[M::mem_pestat] mean and std.dev: (1093.23, 1083.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7145)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 33, #reads = 1113997 mem = 536879969 peak = 1023025152
[M::process] read 765858 sequences (100000077 bp) in 2.503 CPU sec, 2.638 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (14, 303756, 14, 22)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 439, 3710)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10796)
[M::mem_pestat] mean and std.dev: (1296.57, 1562.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14339)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (112, 149, 203)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 385)
[M::mem_pestat] mean and std.dev: (162.00, 67.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 476)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 1180, 1530)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4142)
[M::mem_pestat] mean and std.dev: (965.43, 823.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5448)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 177, 425)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1011)
[M::mem_pestat] mean and std.dev: (250.82, 164.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1304)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 767450 reads in 224.041 CPU sec, 7.070 real sec
[M::process] read 765294 sequences (100000131 bp) in 1.758 CPU sec, 1.770 real sec...
[M::mem_process_seqs] Processed 766820 reads in 137.117 CPU sec, 4.344 real sec
sorting block 34, #reads = 1112035 mem = 536880418 peak = 1023025152
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (21, 303522, 15, 24)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 344, 659)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1529)
[M::mem_pestat] mean and std.dev: (391.22, 276.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1964)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (112, 150, 205)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 391)
[M::mem_pestat] mean and std.dev: (163.17, 68.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 484)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (524, 861, 2848)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7496)
[M::mem_pestat] mean and std.dev: (1624.87, 1566.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9820)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 271, 405)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 841)
[M::mem_pestat] mean and std.dev: (267.32, 126.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1059)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 764122 sequences (100000206 bp) in 2.965 CPU sec, 3.054 real sec...
[M::process] read 762468 sequences (100000011 bp) in 2.059 CPU sec, 2.079 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (18, 303700, 5, 16)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 308, 310)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 566)
[M::mem_pestat] mean and std.dev: (243.40, 86.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 694)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (112, 150, 206)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 394)
[M::mem_pestat] mean and std.dev: (163.74, 69.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 488)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 720, 1047)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2797)
[M::mem_pestat] mean and std.dev: (675.75, 525.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3672)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 765858 reads in 197.792 CPU sec, 6.315 real sec
[M::mem_process_seqs] Processed 765294 reads in 135.095 CPU sec, 4.363 real sec
sorting block 35, #reads = 1112171 mem = 536877392 peak = 1023025152
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (21, 302951, 10, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 213, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 632)
[M::mem_pestat] mean and std.dev: (251.10, 102.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 781)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (112, 151, 207)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 397)
[M::mem_pestat] mean and std.dev: (164.81, 69.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 492)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (235, 2447, 2447)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6871)
[M::mem_pestat] mean and std.dev: (1426.00, 1072.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9083)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (113, 195, 1109)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3101)
[M::mem_pestat] mean and std.dev: (504.53, 608.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4097)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 762612 sequences (100000024 bp) in 2.933 CPU sec, 3.237 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (19, 302151, 13, 17)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 207, 457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1071)
[M::mem_pestat] mean and std.dev: (331.58, 243.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1378)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (113, 152, 208)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 398)
[M::mem_pestat] mean and std.dev: (165.59, 70.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 493)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (111, 348, 1013)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2817)
[M::mem_pestat] mean and std.dev: (513.00, 605.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3719)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 208, 451)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1095)
[M::mem_pestat] mean and std.dev: (279.82, 206.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1417)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 762600 sequences (100000175 bp) in 1.719 CPU sec, 1.740 real sec...
[M::mem_process_seqs] Processed 764122 reads in 200.089 CPU sec, 6.474 real sec
sorting block 36, #reads = 1109233 mem = 536878881 peak = 1023025152
[M::mem_process_seqs] Processed 762468 reads in 138.138 CPU sec, 4.432 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (15, 302201, 8, 18)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (117, 161, 782)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2112)
[M::mem_pestat] mean and std.dev: (372.27, 370.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2777)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (113, 152, 207)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 395)
[M::mem_pestat] mean and std.dev: (165.33, 69.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 489)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (233, 335, 1112)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2870)
[M::mem_pestat] mean and std.dev: (795.00, 841.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4163)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 37, #reads = 1109104 mem = 536878533 peak = 1023025152
[M::process] read 770582 sequences (100000089 bp) in 2.907 CPU sec, 3.083 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (10, 302007, 11, 18)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (136, 242, 401)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 931)
[M::mem_pestat] mean and std.dev: (224.00, 98.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1196)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (113, 152, 208)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 398)
[M::mem_pestat] mean and std.dev: (165.58, 69.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 493)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 573, 2514)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7138)
[M::mem_pestat] mean and std.dev: (1136.73, 1424.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9450)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 200, 1094)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2980)
[M::mem_pestat] mean and std.dev: (440.53, 690.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3923)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 773308 sequences (100000244 bp) in 2.065 CPU sec, 2.109 real sec...
[M::mem_process_seqs] Processed 762612 reads in 205.223 CPU sec, 6.631 real sec
[M::mem_process_seqs] Processed 762600 reads in 142.824 CPU sec, 4.601 real sec
sorting block 38, #reads = 1106345 mem = 536881707 peak = 1023025152
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (21, 304934, 5, 18)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (121, 174, 292)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 634)
[M::mem_pestat] mean and std.dev: (168.94, 66.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 805)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 374)
[M::mem_pestat] mean and std.dev: (158.75, 64.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 462)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 311, 2293)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6569)
[M::mem_pestat] mean and std.dev: (1217.00, 1597.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8707)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 772206 sequences (100000185 bp) in 2.546 CPU sec, 2.700 real sec...
[M::process] read 769956 sequences (100000056 bp) in 1.758 CPU sec, 1.851 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (16, 305646, 9, 14)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 313, 931)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2417)
[M::mem_pestat] mean and std.dev: (449.00, 346.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3160)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 145, 195)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 365)
[M::mem_pestat] mean and std.dev: (156.37, 62.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 450)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (125, 614, 1751)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5003)
[M::mem_pestat] mean and std.dev: (1090.00, 1166.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6629)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 770582 reads in 217.955 CPU sec, 7.009 real sec
sorting block 39, #reads = 1103615 mem = 536878721 peak = 1023025152
[M::mem_process_seqs] Processed 773308 reads in 148.219 CPU sec, 4.786 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (7, 305506, 10, 18)
[M::mem_pestat] skip orientation FF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 146, 197)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 371)
[M::mem_pestat] mean and std.dev: (157.59, 63.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 458)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 574, 1514)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4198)
[M::mem_pestat] mean and std.dev: (1005.70, 1166.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5672)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 419, 1356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3750)
[M::mem_pestat] mean and std.dev: (701.29, 809.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4947)
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 40, #reads = 1111010 mem = 536879436 peak = 1023025152
[M::process] read 769586 sequences (100000187 bp) in 2.925 CPU sec, 3.091 real sec...
[M::process] read 768764 sequences (100000173 bp) in 2.094 CPU sec, 2.095 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20, 304540, 10, 17)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 262, 779)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2031)
[M::mem_pestat] mean and std.dev: (364.00, 312.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2657)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 147, 199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 375)
[M::mem_pestat] mean and std.dev: (159.05, 64.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 463)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (336, 1124, 1858)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4902)
[M::mem_pestat] mean and std.dev: (1218.80, 1033.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6424)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 232, 347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 657)
[M::mem_pestat] mean and std.dev: (253.31, 125.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 812)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 772206 reads in 209.658 CPU sec, 6.736 real sec
[M::mem_process_seqs] Processed 769956 reads in 141.045 CPU sec, 4.596 real sec
sorting block 41, #reads = 1111445 mem = 536876861 peak = 1023025152
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (16, 304477, 14, 11)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (133, 173, 572)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1450)
[M::mem_pestat] mean and std.dev: (275.87, 197.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1889)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 147, 200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 378)
[M::mem_pestat] mean and std.dev: (159.60, 65.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 467)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (123, 229, 531)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1347)
[M::mem_pestat] mean and std.dev: (255.83, 194.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1755)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 388, 706)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1812)
[M::mem_pestat] mean and std.dev: (411.40, 323.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2365)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 768592 sequences (100000031 bp) in 3.101 CPU sec, 3.195 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (16, 305015, 9, 17)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (142, 257, 417)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 967)
[M::mem_pestat] mean and std.dev: (256.13, 152.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1242)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 378)
[M::mem_pestat] mean and std.dev: (160.17, 65.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 467)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 248, 1708)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4830)
[M::mem_pestat] mean and std.dev: (758.71, 874.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6391)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 767176 sequences (100000097 bp) in 1.847 CPU sec, 1.890 real sec...
[M::mem_process_seqs] Processed 769586 reads in 203.481 CPU sec, 6.547 real sec
[M::mem_process_seqs] Processed 768764 reads in 139.229 CPU sec, 4.481 real sec
sorting block 42, #reads = 1110956 mem = 536878616 peak = 1023025152
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (10, 304530, 15, 15)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (230, 306, 926)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2318)
[M::mem_pestat] mean and std.dev: (535.00, 441.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3014)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 381)
[M::mem_pestat] mean and std.dev: (160.43, 66.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 471)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (359, 859, 1282)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3128)
[M::mem_pestat] mean and std.dev: (751.46, 595.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4051)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 187, 440)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 978)
[M::mem_pestat] mean and std.dev: (206.42, 95.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1247)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 765078 sequences (100000098 bp) in 2.858 CPU sec, 3.051 real sec...
[M::process] read 763930 sequences (100000079 bp) in 1.869 CPU sec, 1.906 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (17, 303627, 7, 15)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (107, 169, 591)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1559)
[M::mem_pestat] mean and std.dev: (312.29, 259.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2043)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 149, 202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 384)
[M::mem_pestat] mean and std.dev: (161.25, 66.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 475)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 269, 724)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1768)
[M::mem_pestat] mean and std.dev: (337.31, 289.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2290)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 768592 reads in 207.385 CPU sec, 6.706 real sec
sorting block 43, #reads = 1112617 mem = 536882942 peak = 1023025152
[M::mem_process_seqs] Processed 767176 reads in 144.512 CPU sec, 4.709 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (22, 302785, 11, 13)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 662, 800)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2054)
[M::mem_pestat] mean and std.dev: (620.95, 450.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2681)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (112, 150, 204)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 388)
[M::mem_pestat] mean and std.dev: (162.66, 67.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 480)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 338, 687)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1679)
[M::mem_pestat] mean and std.dev: (317.44, 243.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2175)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 626, 1762)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4938)
[M::mem_pestat] mean and std.dev: (915.31, 783.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6526)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 44, #reads = 1110627 mem = 536879432 peak = 1052008448
[M::process] read 764806 sequences (100000227 bp) in 2.788 CPU sec, 3.215 real sec...
[M::process] read 764818 sequences (100000172 bp) in 2.054 CPU sec, 2.075 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (12, 302715, 13, 18)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (259, 493, 1240)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3202)
[M::mem_pestat] mean and std.dev: (587.55, 482.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4183)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (113, 150, 204)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 386)
[M::mem_pestat] mean and std.dev: (162.94, 67.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 477)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (125, 636, 2336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6758)
[M::mem_pestat] mean and std.dev: (1113.75, 1416.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8969)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 175, 323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 735)
[M::mem_pestat] mean and std.dev: (200.00, 117.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 941)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 765078 reads in 212.194 CPU sec, 6.899 real sec
[M::mem_process_seqs] Processed 763930 reads in 144.992 CPU sec, 4.661 real sec
sorting block 45, #reads = 1106183 mem = 536881061 peak = 1052008448
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (17, 301978, 12, 19)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 228, 655)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1657)
[M::mem_pestat] mean and std.dev: (375.12, 262.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2158)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (112, 150, 203)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 385)
[M::mem_pestat] mean and std.dev: (162.38, 66.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 476)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (143, 440, 1885)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5369)
[M::mem_pestat] mean and std.dev: (1018.50, 1238.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7111)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 231, 2775)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7937)
[M::mem_pestat] mean and std.dev: (1924.26, 2813.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13177)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 764324 sequences (100000155 bp) in 2.698 CPU sec, 2.750 real sec...
[M::process] read 763712 sequences (100000065 bp) in 2.080 CPU sec, 2.082 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (10, 302748, 9, 16)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 462, 1030)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2764)
[M::mem_pestat] mean and std.dev: (485.11, 394.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3631)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (112, 150, 204)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 388)
[M::mem_pestat] mean and std.dev: (162.71, 67.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 480)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (122, 148, 188)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 320)
[M::mem_pestat] mean and std.dev: (147.07, 35.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 386)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 764806 reads in 210.462 CPU sec, 6.740 real sec
sorting block 46, #reads = 1106051 mem = 536882571 peak = 1052008448
[M::mem_process_seqs] Processed 764818 reads in 144.493 CPU sec, 4.584 real sec
sorting block 47, #reads = 1104430 mem = 536877701 peak = 1052008448
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (22, 302344, 9, 19)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 280, 734)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1860)
[M::mem_pestat] mean and std.dev: (445.60, 410.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2423)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (112, 150, 204)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 388)
[M::mem_pestat] mean and std.dev: (163.12, 67.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 480)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 248, 911)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2415)
[M::mem_pestat] mean and std.dev: (535.47, 462.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3167)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 772800 sequences (100000284 bp) in 3.116 CPU sec, 3.172 real sec...
[M::process] read 775330 sequences (100000140 bp) in 2.070 CPU sec, 2.076 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 301904, 13, 14)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 417, 1223)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3363)
[M::mem_pestat] mean and std.dev: (512.40, 663.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4433)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (113, 151, 204)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 386)
[M::mem_pestat] mean and std.dev: (163.07, 67.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 477)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (311, 1135, 6673)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 19397)
[M::mem_pestat] mean and std.dev: (2735.77, 2869.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 25759)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (126, 209, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 714)
[M::mem_pestat] mean and std.dev: (242.54, 154.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 910)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 764324 reads in 201.292 CPU sec, 6.379 real sec
[M::mem_process_seqs] Processed 763712 reads in 138.585 CPU sec, 4.404 real sec
sorting block 48, #reads = 1104256 mem = 536878484 peak = 1052008448
[M::process] read 774136 sequences (100000189 bp) in 2.776 CPU sec, 2.815 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (9, 305142, 16, 22)
[M::mem_pestat] skip orientation FF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 145, 196)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 368)
[M::mem_pestat] mean and std.dev: (157.15, 63.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 454)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (371, 1219, 1856)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4826)
[M::mem_pestat] mean and std.dev: (1110.80, 1069.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6311)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 203, 804)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2100)
[M::mem_pestat] mean and std.dev: (333.65, 309.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2748)
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 772360 sequences (100000180 bp) in 1.990 CPU sec, 1.989 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (8, 305861, 9, 22)
[M::mem_pestat] skip orientation FF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 144, 194)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 364)
[M::mem_pestat] mean and std.dev: (155.48, 62.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 449)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 424, 980)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2628)
[M::mem_pestat] mean and std.dev: (488.75, 432.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3452)
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (17, 305900, 9, 11)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (134, 231, 931)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2525)
[M::mem_pestat] mean and std.dev: (427.67, 460.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3322)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 145, 195)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 367)
[M::mem_pestat] mean and std.dev: (156.31, 63.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 453)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (121, 163, 1377)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3889)
[M::mem_pestat] mean and std.dev: (807.82, 1088.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5160)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 772800 reads in 305.415 CPU sec, 9.751 real sec
[M::mem_process_seqs] Processed 775330 reads in 236.927 CPU sec, 7.593 real sec
sorting block 49, #reads = 1102414 mem = 536885244 peak = 1052008448
[M::mem_process_seqs] Processed 774136 reads in 268.029 CPU sec, 8.603 real sec
[M::process] read 771186 sequences (100000024 bp) in 2.981 CPU sec, 3.074 real sec...
sorting block 50, #reads = 1103462 mem = 536880464 peak = 1052008448
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (12, 305391, 7, 13)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 327, 693)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1755)
[M::mem_pestat] mean and std.dev: (307.30, 203.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2286)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 146, 196)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 368)
[M::mem_pestat] mean and std.dev: (157.43, 63.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 454)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 263, 2102)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5932)
[M::mem_pestat] mean and std.dev: (828.85, 987.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7847)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 769238 sequences (100000138 bp) in 2.497 CPU sec, 2.576 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (12, 305074, 11, 18)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (146, 164, 231)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 401)
[M::mem_pestat] mean and std.dev: (165.10, 36.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 486)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 146, 197)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 371)
[M::mem_pestat] mean and std.dev: (158.05, 63.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 458)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (120, 257, 1063)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2949)
[M::mem_pestat] mean and std.dev: (404.64, 422.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3892)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (126, 212, 1087)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3009)
[M::mem_pestat] mean and std.dev: (673.94, 821.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3970)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 769512 sequences (100000159 bp) in 1.930 CPU sec, 1.930 real sec...
[M::mem_process_seqs] Processed 772360 reads in 218.560 CPU sec, 6.948 real sec
sorting block 51, #reads = 1102101 mem = 536882652 peak = 1052008448
[M::process] read 768498 sequences (100000158 bp) in 2.183 CPU sec, 2.187 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (14, 304159, 14, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (128, 153, 248)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 488)
[M::mem_pestat] mean and std.dev: (184.31, 86.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 608)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 375)
[M::mem_pestat] mean and std.dev: (159.56, 65.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 463)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 319, 1271)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3383)
[M::mem_pestat] mean and std.dev: (733.85, 839.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4439)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 346, 596)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1410)
[M::mem_pestat] mean and std.dev: (404.24, 269.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1817)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 769238 reads in 122.483 CPU sec, 4.216 real sec
[M::mem_process_seqs] Processed 771186 reads in 304.611 CPU sec, 9.992 real sec
sorting block 52, #reads = 1107498 mem = 536880700 peak = 1052008448
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (10, 304863, 9, 16)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (121, 333, 801)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2161)
[M::mem_pestat] mean and std.dev: (448.50, 382.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2841)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 147, 199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 375)
[M::mem_pestat] mean and std.dev: (159.37, 65.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 463)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 216, 287)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 545)
[M::mem_pestat] mean and std.dev: (199.93, 77.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 674)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 766816 sequences (100000250 bp) in 2.505 CPU sec, 2.593 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (19, 304418, 8, 17)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 205, 1071)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2895)
[M::mem_pestat] mean and std.dev: (539.22, 493.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3807)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 378)
[M::mem_pestat] mean and std.dev: (159.98, 65.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 467)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 370, 1783)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4921)
[M::mem_pestat] mean and std.dev: (817.71, 976.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6490)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 765878 sequences (100000283 bp) in 1.960 CPU sec, 1.963 real sec...
[M::mem_process_seqs] Processed 769512 reads in 224.324 CPU sec, 7.134 real sec
sorting block 53, #reads = 1108502 mem = 536878228 peak = 1052008448
[M::mem_process_seqs] Processed 768498 reads in 133.807 CPU sec, 4.243 real sec
sorting block 54, #reads = 1107835 mem = 536881468 peak = 1052008448
[M::process] read 764788 sequences (100000264 bp) in 2.644 CPU sec, 2.725 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (9, 303715, 9, 18)
[M::mem_pestat] skip orientation FF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (112, 149, 202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 382)
[M::mem_pestat] mean and std.dev: (161.37, 66.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 472)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 394, 831)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2179)
[M::mem_pestat] mean and std.dev: (423.33, 317.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2853)
[M::mem_pestat] skip orientation RR
[M::process] read 765214 sequences (100000012 bp) in 1.910 CPU sec, 1.910 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (19, 303198, 10, 22)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (134, 180, 523)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1301)
[M::mem_pestat] mean and std.dev: (310.47, 268.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1690)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (112, 149, 203)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 385)
[M::mem_pestat] mean and std.dev: (162.00, 66.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 476)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (132, 1143, 1865)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5331)
[M::mem_pestat] mean and std.dev: (1649.00, 1834.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8987)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 221, 646)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1602)
[M::mem_pestat] mean and std.dev: (472.71, 485.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2414)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (12, 302546, 12, 17)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 339, 1591)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4457)
[M::mem_pestat] mean and std.dev: (672.91, 699.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5890)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (112, 150, 203)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 385)
[M::mem_pestat] mean and std.dev: (162.36, 66.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 476)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (830, 1189, 1189)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (112, 1907)
[M::mem_pestat] mean and std.dev: (936.00, 315.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2266)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 278, 542)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1300)
[M::mem_pestat] mean and std.dev: (324.25, 232.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1679)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 766816 reads in 277.517 CPU sec, 8.851 real sec
[M::mem_process_seqs] Processed 765878 reads in 213.176 CPU sec, 6.830 real sec
[M::mem_process_seqs] Processed 764788 reads in 237.005 CPU sec, 7.629 real sec
sorting block 55, #reads = 1107135 mem = 536879721 peak = 1052008448
[M::process] read 766032 sequences (100000075 bp) in 2.571 CPU sec, 2.661 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (11, 302429, 19, 12)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (298, 373, 1679)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4441)
[M::mem_pestat] mean and std.dev: (803.09, 641.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5822)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (112, 150, 203)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 385)
[M::mem_pestat] mean and std.dev: (162.05, 66.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 476)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (124, 353, 875)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2377)
[M::mem_pestat] mean and std.dev: (459.24, 540.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3128)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (126, 150, 224)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 420)
[M::mem_pestat] mean and std.dev: (154.20, 40.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 518)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 56, #reads = 1106288 mem = 536885694 peak = 1052008448
[M::process] read 765216 sequences (100000161 bp) in 2.399 CPU sec, 2.466 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (19, 303030, 12, 20)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (144, 228, 505)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1227)
[M::mem_pestat] mean and std.dev: (272.82, 181.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1588)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (112, 149, 202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 382)
[M::mem_pestat] mean and std.dev: (161.65, 66.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 472)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (257, 316, 1035)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2591)
[M::mem_pestat] mean and std.dev: (439.09, 362.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3369)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 276, 594)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1514)
[M::mem_pestat] mean and std.dev: (311.67, 256.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1974)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 765214 reads in 203.480 CPU sec, 6.472 real sec
[M::process] read 774640 sequences (100000114 bp) in 2.014 CPU sec, 2.027 real sec...
[M::mem_process_seqs] Processed 766032 reads in 141.142 CPU sec, 4.449 real sec
sorting block 57, #reads = 1105134 mem = 536887816 peak = 1052008448
[M::process] read 773844 sequences (100000136 bp) in 2.681 CPU sec, 2.754 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 302002, 11, 18)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 440, 1149)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3069)
[M::mem_pestat] mean and std.dev: (723.92, 708.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4029)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (112, 149, 202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 382)
[M::mem_pestat] mean and std.dev: (161.59, 66.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 472)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (458, 574, 873)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1703)
[M::mem_pestat] mean and std.dev: (596.60, 278.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2118)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 266, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 689)
[M::mem_pestat] mean and std.dev: (250.75, 139.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 868)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 772244 sequences (100000198 bp) in 1.891 CPU sec, 1.896 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20, 306627, 5, 20)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 191, 831)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2173)
[M::mem_pestat] mean and std.dev: (413.42, 415.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2844)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 145, 196)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 370)
[M::mem_pestat] mean and std.dev: (156.95, 63.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 457)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 439, 1919)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5403)
[M::mem_pestat] mean and std.dev: (966.70, 959.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7145)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23, 305944, 8, 10)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (280, 567, 1960)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5320)
[M::mem_pestat] mean and std.dev: (937.41, 933.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7000)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 145, 195)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 367)
[M::mem_pestat] mean and std.dev: (156.25, 62.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 453)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 179, 2349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6781)
[M::mem_pestat] mean and std.dev: (1026.80, 1312.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8997)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 765216 reads in 292.512 CPU sec, 9.337 real sec
[M::mem_process_seqs] Processed 773844 reads in 219.437 CPU sec, 7.028 real sec
sorting block 58, #reads = 1103896 mem = 536878572 peak = 1052008448
[M::mem_process_seqs] Processed 774640 reads in 245.403 CPU sec, 7.880 real sec
sorting block 59, #reads = 1104825 mem = 536883709 peak = 1052008448
[M::process] read 769814 sequences (100000233 bp) in 2.857 CPU sec, 2.959 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (15, 305662, 6, 15)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 351, 920)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2416)
[M::mem_pestat] mean and std.dev: (595.73, 569.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3164)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 146, 197)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 371)
[M::mem_pestat] mean and std.dev: (157.78, 64.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 458)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 173, 402)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 944)
[M::mem_pestat] mean and std.dev: (200.83, 113.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1215)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 769106 sequences (100000008 bp) in 2.382 CPU sec, 2.434 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (14, 304906, 8, 16)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (128, 182, 553)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1403)
[M::mem_pestat] mean and std.dev: (343.86, 301.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1828)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 147, 199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 375)
[M::mem_pestat] mean and std.dev: (159.16, 65.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 463)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 283, 791)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2079)
[M::mem_pestat] mean and std.dev: (466.47, 453.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2723)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 772244 reads in 196.747 CPU sec, 6.266 real sec
[M::process] read 768610 sequences (100000261 bp) in 2.037 CPU sec, 2.059 real sec...
sorting block 60, #reads = 1111908 mem = 536879437 peak = 1052008448
[M::mem_process_seqs] Processed 769814 reads in 133.503 CPU sec, 4.207 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (17, 305211, 6, 15)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (127, 244, 478)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1180)
[M::mem_pestat] mean and std.dev: (284.56, 183.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1531)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 378)
[M::mem_pestat] mean and std.dev: (159.97, 65.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 467)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 316, 1498)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4084)
[M::mem_pestat] mean and std.dev: (691.40, 673.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5377)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 61, #reads = 1112072 mem = 536878931 peak = 1052008448
[M::process] read 768496 sequences (100000010 bp) in 2.247 CPU sec, 2.322 real sec...
[M::process] read 768476 sequences (100000095 bp) in 1.660 CPU sec, 1.655 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (13, 304413, 4, 13)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 352, 967)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2509)
[M::mem_pestat] mean and std.dev: (380.55, 256.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3280)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 381)
[M::mem_pestat] mean and std.dev: (160.51, 66.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 471)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 168, 1168)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3212)
[M::mem_pestat] mean and std.dev: (362.58, 404.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4234)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 769106 reads in 190.174 CPU sec, 6.060 real sec
[M::mem_process_seqs] Processed 768610 reads in 127.261 CPU sec, 4.060 real sec
sorting block 62, #reads = 1111585 mem = 536878867 peak = 1052008448
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (14, 304230, 10, 13)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 398, 1100)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2996)
[M::mem_pestat] mean and std.dev: (615.92, 656.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3944)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 381)
[M::mem_pestat] mean and std.dev: (160.62, 66.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 471)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (13, 273, 986)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2932)
[M::mem_pestat] mean and std.dev: (476.40, 561.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3905)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 254, 379)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 839)
[M::mem_pestat] mean and std.dev: (259.58, 134.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1069)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 768970 sequences (100000008 bp) in 2.614 CPU sec, 2.672 real sec...
[M::process] read 769060 sequences (100000081 bp) in 1.980 CPU sec, 1.981 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (19, 304665, 5, 12)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (138, 207, 389)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 891)
[M::mem_pestat] mean and std.dev: (216.38, 135.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1142)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 378)
[M::mem_pestat] mean and std.dev: (160.20, 65.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 467)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 230, 7815)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 23093)
[M::mem_pestat] mean and std.dev: (2371.25, 3775.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 30732)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 768496 reads in 201.841 CPU sec, 6.414 real sec
sorting block 63, #reads = 1112104 mem = 536883521 peak = 1052008448
[M::mem_process_seqs] Processed 768476 reads in 139.276 CPU sec, 4.431 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (21, 304447, 6, 17)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (119, 328, 867)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2363)
[M::mem_pestat] mean and std.dev: (460.20, 407.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3111)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 147, 199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 375)
[M::mem_pestat] mean and std.dev: (159.50, 65.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 463)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 278, 2999)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8671)
[M::mem_pestat] mean and std.dev: (1399.06, 2221.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11507)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 768246 sequences (100000268 bp) in 2.534 CPU sec, 2.600 real sec...
[M::process] read 767076 sequences (100000198 bp) in 1.860 CPU sec, 1.860 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (17, 304531, 4, 14)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 290, 998)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2672)
[M::mem_pestat] mean and std.dev: (333.14, 279.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3509)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 147, 199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 375)
[M::mem_pestat] mean and std.dev: (159.44, 65.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 463)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 155, 249)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 477)
[M::mem_pestat] mean and std.dev: (164.67, 50.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 591)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 768970 reads in 202.097 CPU sec, 6.426 real sec
sorting block 64, #reads = 1111385 mem = 536881874 peak = 1052008448
[M::mem_process_seqs] Processed 769060 reads in 135.048 CPU sec, 4.302 real sec
sorting block 65, #reads = 1109933 mem = 536877166 peak = 1052008448
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (11, 304301, 11, 15)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 425, 1005)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2681)
[M::mem_pestat] mean and std.dev: (549.91, 520.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3519)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 381)
[M::mem_pestat] mean and std.dev: (160.46, 66.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 471)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (256, 659, 5511)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 16021)
[M::mem_pestat] mean and std.dev: (2230.73, 2492.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 21276)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 236, 634)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1606)
[M::mem_pestat] mean and std.dev: (275.46, 201.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2092)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 766174 sequences (100000208 bp) in 2.355 CPU sec, 2.425 real sec...
[M::process] read 766508 sequences (100000152 bp) in 1.680 CPU sec, 1.677 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (12, 303825, 12, 24)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (256, 669, 1017)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2539)
[M::mem_pestat] mean and std.dev: (701.67, 520.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3300)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 149, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 381)
[M::mem_pestat] mean and std.dev: (160.94, 66.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 471)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (315, 726, 1803)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4779)
[M::mem_pestat] mean and std.dev: (763.27, 596.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6267)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 249, 1415)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3891)
[M::mem_pestat] mean and std.dev: (455.38, 477.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5129)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 768246 reads in 196.484 CPU sec, 6.262 real sec
[M::mem_process_seqs] Processed 767076 reads in 136.639 CPU sec, 4.361 real sec
sorting block 66, #reads = 1109531 mem = 536879032 peak = 1052008448
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (14, 303192, 14, 22)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (141, 331, 845)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2253)
[M::mem_pestat] mean and std.dev: (516.07, 513.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2957)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (112, 149, 202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 382)
[M::mem_pestat] mean and std.dev: (161.58, 66.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 472)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 878, 4576)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13410)
[M::mem_pestat] mean and std.dev: (2008.50, 2372.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17827)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 222, 1027)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2787)
[M::mem_pestat] mean and std.dev: (582.81, 689.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3667)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 774718 sequences (100000223 bp) in 2.641 CPU sec, 2.709 real sec...
[M::process] read 777318 sequences (100000071 bp) in 2.030 CPU sec, 2.030 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (12, 303272, 9, 8)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 225, 652)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1566)
[M::mem_pestat] mean and std.dev: (309.18, 201.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2023)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (112, 149, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 379)
[M::mem_pestat] mean and std.dev: (160.95, 65.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 468)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] skip orientation RR as there are not enough pairs
[M::mem_pestat] skip orientation FF
[M::mem_process_seqs] Processed 766174 reads in 205.536 CPU sec, 6.535 real sec
sorting block 67, #reads = 1107975 mem = 536892220 peak = 1052008448
[M::mem_process_seqs] Processed 766508 reads in 145.741 CPU sec, 4.632 real sec
[M::process] read 776454 sequences (100000093 bp) in 2.564 CPU sec, 2.628 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (17, 305679, 8, 3)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 642, 1616)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4516)
[M::mem_pestat] mean and std.dev: (825.19, 754.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5966)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 144, 194)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 364)
[M::mem_pestat] mean and std.dev: (155.92, 62.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 449)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] skip orientation RR as there are not enough pairs
[M::mem_pestat] skip orientation FF
[M::process] read 776194 sequences (100000009 bp) in 1.770 CPU sec, 1.772 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (8, 307071, 7, 16)
[M::mem_pestat] skip orientation FF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (108, 143, 192)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 360)
[M::mem_pestat] mean and std.dev: (154.38, 61.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 444)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 231, 432)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 996)
[M::mem_pestat] mean and std.dev: (241.71, 132.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1278)
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 307050, 10, 9)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (134, 171, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 764)
[M::mem_pestat] mean and std.dev: (198.14, 105.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 974)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 144, 193)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 361)
[M::mem_pestat] mean and std.dev: (154.87, 61.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 445)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 648, 1360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3760)
[M::mem_pestat] mean and std.dev: (726.60, 598.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4960)
[M::mem_pestat] skip orientation RR as there are not enough pairs
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_process_seqs] Processed 774718 reads in 317.908 CPU sec, 10.161 real sec
sorting block 68, #reads = 1102895 mem = 536886296 peak = 1052008448
[M::mem_process_seqs] Processed 777318 reads in 242.616 CPU sec, 7.793 real sec
[M::mem_process_seqs] Processed 776454 reads in 272.733 CPU sec, 8.779 real sec
sorting block 69, #reads = 1102919 mem = 536881612 peak = 1093558272
[M::process] read 773182 sequences (100000151 bp) in 2.723 CPU sec, 2.799 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20, 306633, 10, 17)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (135, 242, 450)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1080)
[M::mem_pestat] mean and std.dev: (276.67, 182.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1395)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 144, 193)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 361)
[M::mem_pestat] mean and std.dev: (155.24, 62.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 445)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 439, 475)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1121)
[M::mem_pestat] mean and std.dev: (257.12, 161.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1444)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 428, 924)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2420)
[M::mem_pestat] mean and std.dev: (599.59, 516.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3168)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 70, #reads = 1106442 mem = 536882484 peak = 1093558272
[M::process] read 771724 sequences (100000159 bp) in 2.376 CPU sec, 2.480 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (18, 306175, 10, 18)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (94, 163, 1393)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3991)
[M::mem_pestat] mean and std.dev: (684.59, 1028.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5290)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 145, 196)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 368)
[M::mem_pestat] mean and std.dev: (157.17, 63.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 454)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (133, 334, 1253)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3493)
[M::mem_pestat] mean and std.dev: (719.90, 792.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4613)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 218, 1517)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4251)
[M::mem_pestat] mean and std.dev: (740.65, 974.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5618)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 770876 sequences (100000263 bp) in 1.950 CPU sec, 1.947 real sec...
[M::mem_process_seqs] Processed 776194 reads in 218.040 CPU sec, 6.920 real sec
[M::mem_process_seqs] Processed 773182 reads in 145.119 CPU sec, 4.587 real sec
sorting block 71, #reads = 1104814 mem = 536883991 peak = 1093558272
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (13, 305257, 21, 11)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (97, 151, 218)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 460)
[M::mem_pestat] mean and std.dev: (161.75, 68.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 581)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 146, 197)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 371)
[M::mem_pestat] mean and std.dev: (158.00, 64.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 458)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (338, 716, 5069)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 14531)
[M::mem_pestat] mean and std.dev: (2230.24, 3067.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 19262)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 244, 720)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1712)
[M::mem_pestat] mean and std.dev: (278.22, 178.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2208)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 770384 sequences (100000016 bp) in 2.693 CPU sec, 2.793 real sec...
[M::process] read 769916 sequences (100000156 bp) in 1.760 CPU sec, 1.761 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (17, 305419, 5, 24)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 299, 913)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2435)
[M::mem_pestat] mean and std.dev: (434.80, 385.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3196)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 374)
[M::mem_pestat] mean and std.dev: (158.54, 64.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 462)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 306, 810)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2072)
[M::mem_pestat] mean and std.dev: (459.61, 429.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2703)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 771724 reads in 203.553 CPU sec, 6.470 real sec
sorting block 72, #reads = 1109033 mem = 536881153 peak = 1093558272
[M::mem_process_seqs] Processed 770876 reads in 137.513 CPU sec, 4.388 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (11, 305168, 11, 12)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 247, 886)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2356)
[M::mem_pestat] mean and std.dev: (572.27, 640.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3136)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::process] read 768632 sequences (100000190 bp) in 2.618 CPU sec, 2.693 real sec...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 374)
[M::mem_pestat] mean and std.dev: (158.62, 64.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 462)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (514, 827, 1192)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2548)
[M::mem_pestat] mean and std.dev: (774.20, 338.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3226)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 226, 2602)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7530)
[M::mem_pestat] mean and std.dev: (1095.25, 1613.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9994)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 767942 sequences (100000030 bp) in 1.560 CPU sec, 1.561 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (18, 305273, 14, 17)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (361, 956, 956)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2146)
[M::mem_pestat] mean and std.dev: (803.89, 529.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2923)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 147, 199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 375)
[M::mem_pestat] mean and std.dev: (159.42, 65.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 463)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (504, 1365, 2424)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6264)
[M::mem_pestat] mean and std.dev: (1171.92, 835.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8184)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 404, 2327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6667)
[M::mem_pestat] mean and std.dev: (1085.18, 1282.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8837)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 770384 reads in 196.431 CPU sec, 6.252 real sec
sorting block 73, #reads = 1109922 mem = 536878367 peak = 1093558272
[M::mem_process_seqs] Processed 769916 reads in 133.589 CPU sec, 4.272 real sec
sorting block 74, #reads = 1108313 mem = 536880330 peak = 1093558272
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (19, 304210, 9, 17)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (124, 185, 530)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1342)
[M::mem_pestat] mean and std.dev: (257.31, 239.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1748)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 378)
[M::mem_pestat] mean and std.dev: (160.18, 65.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 467)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (108, 217, 523)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1353)
[M::mem_pestat] mean and std.dev: (326.88, 300.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1768)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 766696 sequences (100000115 bp) in 2.606 CPU sec, 2.694 real sec...
[M::process] read 766144 sequences (100000216 bp) in 2.150 CPU sec, 2.146 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (16, 304611, 6, 18)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 474, 1975)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5605)
[M::mem_pestat] mean and std.dev: (985.62, 926.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7420)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 381)
[M::mem_pestat] mean and std.dev: (160.76, 66.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 471)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (113, 161, 1552)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4430)
[M::mem_pestat] mean and std.dev: (719.88, 836.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5869)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 768632 reads in 190.896 CPU sec, 6.053 real sec
[M::mem_process_seqs] Processed 767942 reads in 128.042 CPU sec, 4.054 real sec
sorting block 75, #reads = 1110812 mem = 536880789 peak = 1093558272
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (14, 303918, 9, 10)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (140, 372, 439)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1037)
[M::mem_pestat] mean and std.dev: (338.92, 238.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1336)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (112, 149, 203)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 385)
[M::mem_pestat] mean and std.dev: (161.84, 67.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 476)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 278, 693)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1621)
[M::mem_pestat] mean and std.dev: (424.40, 243.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2085)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 731764 sequences (95689327 bp) in 2.527 CPU sec, 2.569 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (9, 303459, 7, 15)
[M::mem_pestat] skip orientation FF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (112, 149, 203)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 385)
[M::mem_pestat] mean and std.dev: (162.17, 67.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 476)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 190, 297)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 623)
[M::mem_pestat] mean and std.dev: (176.92, 70.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 786)
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 766696 reads in 188.811 CPU sec, 6.059 real sec
sorting block 76, #reads = 1109326 mem = 536883979 peak = 1093558272
[M::mem_process_seqs] Processed 766144 reads in 130.408 CPU sec, 4.205 real sec
sorting block 77, #reads = 1109981 mem = 536880766 peak = 1144913920
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (14, 289870, 21, 17)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (141, 219, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 744)
[M::mem_pestat] mean and std.dev: (214.67, 109.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 945)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (112, 150, 204)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 388)
[M::mem_pestat] mean and std.dev: (163.14, 67.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 480)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (432, 583, 733)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1335)
[M::mem_pestat] mean and std.dev: (502.88, 183.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1636)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 174, 1037)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2803)
[M::mem_pestat] mean and std.dev: (515.06, 508.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3686)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 731764 reads in 104.360 CPU sec, 3.427 real sec
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000a06d1
  features: bfebfbff 7ffefbff
  extended: f3bfb7ef fb417ffe
  amd bits: 2c100800 00000121
     brand: Intel(R) Xeon(R) 6975P-C
threads: 31
algo: bwa-mem
license: sentieon:klib=31
reads: 86710432
overall: 71823896576 mem 14068.885 user 516.074 sys 483.976 real
[main] Version: 0.7.17-r1188
[main] CMD: /opt/conda/share/sentieon-202308.03-3/libexec/bwa mem -K 100000000 -Y -R @RG\tID:A23MHWWLT4.1029_IWL-T1-TDNA-1_A23MHWWLT4_1.L006\tPU:L006\tSM:1029_IWL-T1-TDNA-1_A23MHWWLT4_1\tLB:1029_IWL-T1-TDNA-1_A23MHWWLT4_1\tDS:s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta\tPL:ILLUMINA -t 31 ./BWAIndex/Homo_sapiens_assembly38.fasta.64 1029_IWL-T1-TDNA-1_A23MHWWLT4_1_R1.fastq.gz 1029_IWL-T1-TDNA-1_A23MHWWLT4_1_R2.fastq.gz
[main] Real time: 484.018 sec; CPU: 14584.968 sec
sorting block 78, #reads = 862514 mem = 418944401 peak = 1144913920
uniq header count 1
merging 79 blocks
sw version: sentieon-genomics-202308.03
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000a06d1
  features: bfebfbff 7ffefbff
  extended: f3bfb7ef fb417ffe
  amd bits: 2c100800 00000121
     brand: Intel(R) Xeon(R) 6975P-C
threads: 31 max 192
algo: util-sort
license: sentieon:util=1
output file size: 4923585970
output reads: 87355560
bam_mem_sort: 79 calls 43.730 user 1.390 sys 45.393 real
bam_write: 79 calls 25.339 user 1.737 sys 31.973 real
execute: 1 calls 25.834 user 1.163 sys 513.944 real
merge_files: 1 calls 25.820 user 1.129 sys 29.371 real
parse_chunk: 1261 calls 52.603 user 12.328 sys 67.352 real
read_chunk: 3435 calls 30.039 user 24.562 sys 423.706 real
sort_block: 1 calls 19.261 user 24.072 sys 409.210 real
write_chunk: 2172 calls 25.396 user 0.876 sys 28.413 real
overall: 3514683392 mem 1145.357 user 54.073 sys 513.965 real
ls: cannot access '*.cram': No such file or directory