cmdline: /opt/conda/share/sentieon-202308.03-3/libexec/util sort -r Homo_sapiens_assembly38.fasta -t 31 -o 1136_5TB-T1-TDNA-1_A23MHWWLT4_1.bam --sam2bam -
This software is licensed to bgold@natera.com by Sentieon Inc.
This software is licensed to bgold@natera.com by Sentieon Inc.
version: sentieon-genomics-202308.03
[M::bwa_idx_load_from_disk] read 3171 ALT contigs
[M::main_mem] bwa index loaded in 1890.167 CPU sec, 65.745 real sec
[M::process] read 699694 sequences (100000223 bp) in 0.986 CPU sec, 0.991 real sec...
[M::process] read 697292 sequences (100000117 bp) in 1.582 CPU sec, 1.633 real sec...
[M::process] read 696330 sequences (100000300 bp) in 1.586 CPU sec, 1.646 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 286730, 19, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 295, 577)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1411)
[M::mem_pestat] mean and std.dev: (393.06, 336.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1828)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 239, 346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 718)
[M::mem_pestat] mean and std.dev: (263.21, 130.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 904)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (420, 912, 2869)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7767)
[M::mem_pestat] mean and std.dev: (1580.44, 1433.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10216)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 230, 455)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1041)
[M::mem_pestat] mean and std.dev: (250.61, 161.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1334)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695470 sequences (100000208 bp) in 1.586 CPU sec, 1.655 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 285423, 15, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 262, 320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 610)
[M::mem_pestat] mean and std.dev: (250.15, 114.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 755)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 250, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 751)
[M::mem_pestat] mean and std.dev: (274.12, 136.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 946)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (248, 564, 680)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1544)
[M::mem_pestat] mean and std.dev: (512.00, 368.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1985)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 225, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 637)
[M::mem_pestat] mean and std.dev: (235.89, 97.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 790)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 285932, 13, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 315, 1296)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3470)
[M::mem_pestat] mean and std.dev: (748.53, 863.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4557)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 246, 355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 737)
[M::mem_pestat] mean and std.dev: (269.91, 133.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 928)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 386, 1516)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4186)
[M::mem_pestat] mean and std.dev: (760.85, 773.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5521)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 279, 465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1075)
[M::mem_pestat] mean and std.dev: (289.19, 158.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1380)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699694 reads in 273.866 CPU sec, 8.926 real sec
[M::mem_process_seqs] Processed 696330 reads in 189.739 CPU sec, 6.217 real sec
[M::mem_process_seqs] Processed 697292 reads in 207.299 CPU sec, 6.792 real sec
sorting block 0, #reads = 1085004 mem = 536879159 peak = 598609920
[M::process] read 694588 sequences (100000078 bp) in 2.231 CPU sec, 2.359 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 285154, 14, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (254, 338, 590)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1262)
[M::mem_pestat] mean and std.dev: (389.12, 217.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1598)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 253, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 756)
[M::mem_pestat] mean and std.dev: (276.26, 136.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 952)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (470, 1707, 3589)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9827)
[M::mem_pestat] mean and std.dev: (2654.57, 3102.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 15063)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 280, 452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 964)
[M::mem_pestat] mean and std.dev: (299.95, 166.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1220)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695054 sequences (100000099 bp) in 1.852 CPU sec, 1.892 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 284665, 14, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (130, 250, 1146)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3178)
[M::mem_pestat] mean and std.dev: (593.14, 778.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4194)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 253, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 757)
[M::mem_pestat] mean and std.dev: (277.59, 137.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 953)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (339, 854, 1112)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2658)
[M::mem_pestat] mean and std.dev: (839.79, 659.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3479)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 269, 598)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1392)
[M::mem_pestat] mean and std.dev: (341.96, 230.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1789)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694602 sequences (100000081 bp) in 1.594 CPU sec, 1.605 real sec...
[M::mem_process_seqs] Processed 695470 reads in 171.059 CPU sec, 5.432 real sec
sorting block 1, #reads = 1083861 mem = 536882790 peak = 899026944
[M::mem_process_seqs] Processed 694588 reads in 111.997 CPU sec, 3.536 real sec
sorting block 2, #reads = 1082349 mem = 536878153 peak = 899026944
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 285057, 23, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 333, 716)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1714)
[M::mem_pestat] mean and std.dev: (473.39, 419.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2213)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 251, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 747)
[M::mem_pestat] mean and std.dev: (274.58, 135.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 940)
[M::process] read 694120 sequences (100000300 bp) in 2.273 CPU sec, 2.381 real sec...
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 750, 1559)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4287)
[M::mem_pestat] mean and std.dev: (608.37, 528.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5651)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 433, 665)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1551)
[M::mem_pestat] mean and std.dev: (426.60, 306.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1994)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 692542 sequences (100000172 bp) in 1.693 CPU sec, 1.709 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 284709, 39, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 251, 705)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1783)
[M::mem_pestat] mean and std.dev: (404.86, 425.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2322)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 252, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 748)
[M::mem_pestat] mean and std.dev: (275.61, 135.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 941)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (269, 698, 2416)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6710)
[M::mem_pestat] mean and std.dev: (1168.05, 1120.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8857)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 393, 917)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2369)
[M::mem_pestat] mean and std.dev: (576.36, 524.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3095)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695054 reads in 170.984 CPU sec, 5.437 real sec
[M::mem_process_seqs] Processed 694602 reads in 112.284 CPU sec, 3.594 real sec
sorting block 3, #reads = 1083313 mem = 536879861 peak = 899026944
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 284888, 24, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 359, 487)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1091)
[M::mem_pestat] mean and std.dev: (325.30, 200.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1393)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 253, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 751)
[M::mem_pestat] mean and std.dev: (276.43, 135.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 945)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (410, 1068, 2790)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7550)
[M::mem_pestat] mean and std.dev: (1652.04, 1882.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9930)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 285, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 702)
[M::mem_pestat] mean and std.dev: (252.39, 100.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 871)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 692642 sequences (100000220 bp) in 2.173 CPU sec, 2.308 real sec...
[M::process] read 691944 sequences (100000185 bp) in 1.753 CPU sec, 1.785 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 283610, 20, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (131, 207, 874)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2360)
[M::mem_pestat] mean and std.dev: (359.79, 438.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3103)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 258, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 752)
[M::mem_pestat] mean and std.dev: (279.82, 135.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 945)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (371, 759, 1315)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3203)
[M::mem_pestat] mean and std.dev: (962.85, 829.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4281)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 311, 489)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1073)
[M::mem_pestat] mean and std.dev: (314.64, 192.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1365)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 694120 reads in 168.339 CPU sec, 5.414 real sec
[M::mem_process_seqs] Processed 692542 reads in 116.345 CPU sec, 3.770 real sec
sorting block 4, #reads = 1081517 mem = 536878771 peak = 899026944
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 283958, 18, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 385, 959)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2451)
[M::mem_pestat] mean and std.dev: (465.39, 371.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3197)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 259, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 752)
[M::mem_pestat] mean and std.dev: (279.58, 134.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 945)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (249, 662, 839)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2019)
[M::mem_pestat] mean and std.dev: (542.25, 384.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2609)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 243, 494)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1114)
[M::mem_pestat] mean and std.dev: (355.56, 252.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1424)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698384 sequences (100000128 bp) in 2.485 CPU sec, 2.811 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 283790, 19, 78)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (142, 239, 622)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1582)
[M::mem_pestat] mean and std.dev: (353.42, 312.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2062)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 262, 372)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 768)
[M::mem_pestat] mean and std.dev: (283.75, 137.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 966)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (240, 612, 2017)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5571)
[M::mem_pestat] mean and std.dev: (1096.32, 1278.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7348)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 321, 499)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1181)
[M::mem_pestat] mean and std.dev: (313.61, 232.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1522)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697692 sequences (100000051 bp) in 1.722 CPU sec, 1.732 real sec...
[M::mem_process_seqs] Processed 692642 reads in 179.397 CPU sec, 5.766 real sec
sorting block 5, #reads = 1081793 mem = 536881154 peak = 899026944
[M::mem_process_seqs] Processed 691944 reads in 121.569 CPU sec, 3.934 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 286356, 18, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 347, 776)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1942)
[M::mem_pestat] mean and std.dev: (468.50, 383.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2525)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 243, 352)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 732)
[M::mem_pestat] mean and std.dev: (267.29, 132.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 922)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (579, 786, 1348)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2886)
[M::mem_pestat] mean and std.dev: (1011.78, 605.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3655)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 265, 855)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2265)
[M::mem_pestat] mean and std.dev: (396.30, 389.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2970)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 6, #reads = 1080216 mem = 536882091 peak = 899026944
[M::process] read 696284 sequences (100000292 bp) in 2.538 CPU sec, 2.962 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 286129, 21, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 398, 1551)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4257)
[M::mem_pestat] mean and std.dev: (703.44, 794.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5610)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 246, 357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 743)
[M::mem_pestat] mean and std.dev: (270.54, 134.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 936)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 553, 3361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9669)
[M::mem_pestat] mean and std.dev: (1664.14, 1863.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12823)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 280, 1205)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3243)
[M::mem_pestat] mean and std.dev: (616.63, 735.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4262)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695702 sequences (100000121 bp) in 1.775 CPU sec, 1.786 real sec...
[M::mem_process_seqs] Processed 698384 reads in 179.767 CPU sec, 5.935 real sec
[M::mem_process_seqs] Processed 697692 reads in 117.373 CPU sec, 3.923 real sec
sorting block 7, #reads = 1084403 mem = 536886222 peak = 899026944
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 285794, 12, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 332, 410)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 882)
[M::mem_pestat] mean and std.dev: (331.41, 185.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1118)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 251, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 757)
[M::mem_pestat] mean and std.dev: (275.08, 137.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 954)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (569, 1136, 1752)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4118)
[M::mem_pestat] mean and std.dev: (1131.18, 825.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5301)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 252, 599)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1417)
[M::mem_pestat] mean and std.dev: (294.67, 222.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1826)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694456 sequences (100000095 bp) in 2.471 CPU sec, 2.960 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 285132, 19, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 221, 871)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2287)
[M::mem_pestat] mean and std.dev: (421.57, 462.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2995)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 253, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 765)
[M::mem_pestat] mean and std.dev: (277.63, 138.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 964)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (225, 444, 964)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2442)
[M::mem_pestat] mean and std.dev: (543.67, 468.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3181)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 289, 411)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 803)
[M::mem_pestat] mean and std.dev: (288.38, 113.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 999)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695084 sequences (100000059 bp) in 1.801 CPU sec, 1.860 real sec...
[M::mem_process_seqs] Processed 696284 reads in 183.397 CPU sec, 5.984 real sec
[M::mem_process_seqs] Processed 695702 reads in 116.981 CPU sec, 3.831 real sec
sorting block 8, #reads = 1085399 mem = 536878208 peak = 899026944
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 284812, 16, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 283, 976)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2634)
[M::mem_pestat] mean and std.dev: (682.75, 732.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3615)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 255, 369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 769)
[M::mem_pestat] mean and std.dev: (279.63, 139.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 969)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (369, 661, 1215)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2907)
[M::mem_pestat] mean and std.dev: (680.80, 524.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3753)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 384, 554)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1266)
[M::mem_pestat] mean and std.dev: (337.86, 197.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1622)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694870 sequences (100000001 bp) in 2.880 CPU sec, 3.280 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 285015, 38, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 447, 1049)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2717)
[M::mem_pestat] mean and std.dev: (593.36, 478.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3551)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 252, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 753)
[M::mem_pestat] mean and std.dev: (275.95, 136.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 948)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 684, 1409)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3823)
[M::mem_pestat] mean and std.dev: (671.53, 754.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5030)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 386, 1177)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3119)
[M::mem_pestat] mean and std.dev: (636.62, 749.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4090)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 694456 reads in 180.258 CPU sec, 5.843 real sec
[M::process] read 694480 sequences (100000276 bp) in 1.863 CPU sec, 1.957 real sec...
sorting block 9, #reads = 1084268 mem = 536882101 peak = 899026944
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 285029, 25, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 321, 546)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1208)
[M::mem_pestat] mean and std.dev: (408.21, 272.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1539)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 251, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 750)
[M::mem_pestat] mean and std.dev: (275.19, 135.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 944)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (227, 420, 1199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3143)
[M::mem_pestat] mean and std.dev: (671.04, 665.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4115)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 269, 407)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 853)
[M::mem_pestat] mean and std.dev: (289.00, 176.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1076)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 693964 sequences (100000196 bp) in 1.896 CPU sec, 1.929 real sec...
[M::mem_process_seqs] Processed 694870 reads in 99.938 CPU sec, 3.192 real sec
[M::mem_process_seqs] Processed 695084 reads in 252.028 CPU sec, 8.080 real sec
sorting block 10, #reads = 1082654 mem = 536885776 peak = 899026944
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 284690, 21, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (112, 159, 383)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 925)
[M::mem_pestat] mean and std.dev: (211.47, 151.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1196)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 252, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 747)
[M::mem_pestat] mean and std.dev: (275.12, 135.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 940)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (482, 679, 1351)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3089)
[M::mem_pestat] mean and std.dev: (730.26, 496.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3958)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 355, 604)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1402)
[M::mem_pestat] mean and std.dev: (365.55, 255.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1801)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 693388 sequences (100000183 bp) in 3.006 CPU sec, 3.419 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 284411, 15, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 259, 423)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 927)
[M::mem_pestat] mean and std.dev: (263.33, 118.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1179)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 255, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 758)
[M::mem_pestat] mean and std.dev: (278.47, 137.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 954)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (291, 408, 2234)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6120)
[M::mem_pestat] mean and std.dev: (1013.21, 1459.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8063)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (236, 361, 1027)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2609)
[M::mem_pestat] mean and std.dev: (478.88, 385.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3400)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 694480 reads in 195.260 CPU sec, 6.318 real sec
[M::mem_process_seqs] Processed 693964 reads in 119.335 CPU sec, 3.887 real sec
sorting block 11, #reads = 1081795 mem = 536880854 peak = 899026944
[M::process] read 692412 sequences (100000226 bp) in 2.230 CPU sec, 2.380 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 283910, 19, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 306, 795)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2077)
[M::mem_pestat] mean and std.dev: (466.46, 514.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2718)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 257, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 759)
[M::mem_pestat] mean and std.dev: (279.18, 136.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 955)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (566, 964, 2409)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6095)
[M::mem_pestat] mean and std.dev: (1164.65, 1187.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7938)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (258, 346, 646)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1422)
[M::mem_pestat] mean and std.dev: (350.98, 188.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1810)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698408 sequences (100000297 bp) in 2.734 CPU sec, 3.056 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 283938, 16, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (146, 284, 1051)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2861)
[M::mem_pestat] mean and std.dev: (455.29, 521.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3766)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 260, 371)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 767)
[M::mem_pestat] mean and std.dev: (282.64, 138.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 965)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (350, 832, 1553)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3959)
[M::mem_pestat] mean and std.dev: (1029.00, 934.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5162)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (232, 362, 480)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 976)
[M::mem_pestat] mean and std.dev: (352.16, 185.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1224)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 693388 reads in 177.223 CPU sec, 5.700 real sec
sorting block 12, #reads = 1080952 mem = 536879090 peak = 899026944
[M::process] read 697608 sequences (100000138 bp) in 1.869 CPU sec, 1.902 real sec...
[M::mem_process_seqs] Processed 692412 reads in 119.399 CPU sec, 3.805 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 285828, 21, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 262, 563)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1335)
[M::mem_pestat] mean and std.dev: (347.75, 259.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1721)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 243, 351)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 729)
[M::mem_pestat] mean and std.dev: (266.82, 132.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 918)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (128, 411, 1348)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3788)
[M::mem_pestat] mean and std.dev: (566.83, 789.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5008)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (253, 463, 717)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1645)
[M::mem_pestat] mean and std.dev: (416.31, 223.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2109)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 13, #reads = 1080581 mem = 536878795 peak = 930435072
[M::process] read 695918 sequences (100000298 bp) in 2.460 CPU sec, 2.625 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 285506, 17, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 258, 841)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2129)
[M::mem_pestat] mean and std.dev: (371.89, 350.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2773)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 245, 354)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 736)
[M::mem_pestat] mean and std.dev: (268.99, 132.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 927)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 320, 1918)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5452)
[M::mem_pestat] mean and std.dev: (740.00, 828.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7219)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (252, 376, 742)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1722)
[M::mem_pestat] mean and std.dev: (438.81, 262.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2212)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695202 sequences (100000239 bp) in 1.978 CPU sec, 1.995 real sec...
[M::mem_process_seqs] Processed 698408 reads in 178.969 CPU sec, 5.757 real sec
[M::mem_process_seqs] Processed 697608 reads in 121.695 CPU sec, 3.893 real sec
sorting block 14, #reads = 1083656 mem = 536884544 peak = 930435072
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 285136, 32, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 390, 827)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2133)
[M::mem_pestat] mean and std.dev: (399.90, 300.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2786)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 251, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 746)
[M::mem_pestat] mean and std.dev: (273.58, 134.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 939)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (403, 627, 795)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1579)
[M::mem_pestat] mean and std.dev: (544.55, 328.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1971)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (233, 346, 497)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1025)
[M::mem_pestat] mean and std.dev: (339.14, 151.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1289)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694434 sequences (100000168 bp) in 2.786 CPU sec, 3.163 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 285316, 32, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 301, 487)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1065)
[M::mem_pestat] mean and std.dev: (323.68, 192.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1354)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 253, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 756)
[M::mem_pestat] mean and std.dev: (276.45, 136.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 952)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (232, 1435, 2455)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6901)
[M::mem_pestat] mean and std.dev: (1481.88, 1378.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9124)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 280, 651)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1557)
[M::mem_pestat] mean and std.dev: (347.08, 267.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2010)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695918 reads in 177.683 CPU sec, 5.757 real sec
[M::process] read 694538 sequences (100000095 bp) in 1.951 CPU sec, 2.028 real sec...
[M::mem_process_seqs] Processed 695202 reads in 120.703 CPU sec, 3.866 real sec
sorting block 15, #reads = 1082658 mem = 536879946 peak = 930435072
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 284694, 25, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 260, 792)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2036)
[M::mem_pestat] mean and std.dev: (519.97, 523.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2658)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 256, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 761)
[M::mem_pestat] mean and std.dev: (279.08, 137.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 958)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (568, 911, 2580)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6604)
[M::mem_pestat] mean and std.dev: (1185.23, 797.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8616)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 271, 456)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 972)
[M::mem_pestat] mean and std.dev: (274.41, 132.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1230)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694640 sequences (100000003 bp) in 2.922 CPU sec, 3.233 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 284215, 22, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (139, 214, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 700)
[M::mem_pestat] mean and std.dev: (226.56, 125.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 887)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 254, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 760)
[M::mem_pestat] mean and std.dev: (278.29, 137.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 957)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (139, 597, 1129)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3109)
[M::mem_pestat] mean and std.dev: (485.42, 408.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4099)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 317, 912)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2364)
[M::mem_pestat] mean and std.dev: (526.05, 506.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3090)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 694434 reads in 180.189 CPU sec, 5.818 real sec
[M::process] read 693924 sequences (100000058 bp) in 2.063 CPU sec, 2.134 real sec...
[M::mem_process_seqs] Processed 694538 reads in 122.293 CPU sec, 3.893 real sec
sorting block 16, #reads = 1083062 mem = 536878069 peak = 930435072
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 285074, 22, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 270, 430)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 950)
[M::mem_pestat] mean and std.dev: (269.19, 157.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1210)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 252, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 756)
[M::mem_pestat] mean and std.dev: (276.50, 136.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 952)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (471, 1008, 1313)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2997)
[M::mem_pestat] mean and std.dev: (777.35, 448.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3839)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 300, 550)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1288)
[M::mem_pestat] mean and std.dev: (349.96, 275.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1657)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 17, #reads = 1081539 mem = 536879733 peak = 941506560
[M::process] read 694036 sequences (100000075 bp) in 2.829 CPU sec, 3.261 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 284079, 22, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 243, 430)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 984)
[M::mem_pestat] mean and std.dev: (279.09, 186.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1261)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 254, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 751)
[M::mem_pestat] mean and std.dev: (276.69, 135.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 945)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (360, 715, 2366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6378)
[M::mem_pestat] mean and std.dev: (1364.86, 1392.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8384)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 354, 1290)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3418)
[M::mem_pestat] mean and std.dev: (417.80, 351.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4482)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 694640 reads in 179.331 CPU sec, 5.812 real sec
[M::mem_process_seqs] Processed 693924 reads in 121.635 CPU sec, 3.910 real sec
[M::process] read 693114 sequences (100000174 bp) in 2.101 CPU sec, 2.262 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 284250, 10, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 323, 1111)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2891)
[M::mem_pestat] mean and std.dev: (613.44, 668.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3781)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 255, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 758)
[M::mem_pestat] mean and std.dev: (278.18, 136.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 954)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (622, 1533, 1664)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3748)
[M::mem_pestat] mean and std.dev: (1283.60, 987.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5234)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 291, 379)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 739)
[M::mem_pestat] mean and std.dev: (248.51, 90.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 919)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 18, #reads = 1081914 mem = 536877012 peak = 941506560
[M::process] read 692284 sequences (100000230 bp) in 2.707 CPU sec, 3.069 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 284253, 13, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (144, 243, 410)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 942)
[M::mem_pestat] mean and std.dev: (244.67, 166.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1208)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 258, 369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 763)
[M::mem_pestat] mean and std.dev: (280.86, 137.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 960)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (72, 541, 1069)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3063)
[M::mem_pestat] mean and std.dev: (563.25, 613.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4060)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 307, 838)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2064)
[M::mem_pestat] mean and std.dev: (424.19, 328.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2677)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 694036 reads in 177.185 CPU sec, 5.716 real sec
[M::mem_process_seqs] Processed 693114 reads in 120.708 CPU sec, 3.859 real sec
[M::process] read 698698 sequences (100000082 bp) in 2.197 CPU sec, 2.304 real sec...
sorting block 19, #reads = 1080345 mem = 536877295 peak = 941506560
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 283960, 19, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 288, 538)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1208)
[M::mem_pestat] mean and std.dev: (350.56, 261.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1543)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 261, 372)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 768)
[M::mem_pestat] mean and std.dev: (283.26, 138.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 966)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (672, 883, 1633)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3555)
[M::mem_pestat] mean and std.dev: (844.53, 377.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4516)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (249, 383, 1114)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2844)
[M::mem_pestat] mean and std.dev: (516.25, 471.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3709)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697714 sequences (100000074 bp) in 2.651 CPU sec, 2.986 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 286113, 17, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 241, 680)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1694)
[M::mem_pestat] mean and std.dev: (380.27, 304.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2201)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 241, 350)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 728)
[M::mem_pestat] mean and std.dev: (266.28, 133.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 917)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (111, 479, 858)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2352)
[M::mem_pestat] mean and std.dev: (406.47, 334.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3099)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 296, 529)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1195)
[M::mem_pestat] mean and std.dev: (331.50, 205.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1528)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 692284 reads in 175.134 CPU sec, 5.659 real sec
[M::mem_process_seqs] Processed 698698 reads in 119.991 CPU sec, 3.822 real sec
[M::process] read 697334 sequences (100000230 bp) in 2.028 CPU sec, 2.099 real sec...
sorting block 20, #reads = 1081468 mem = 536878119 peak = 941506560
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 286047, 23, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 465, 1323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3649)
[M::mem_pestat] mean and std.dev: (765.09, 762.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4812)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 244, 355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 739)
[M::mem_pestat] mean and std.dev: (269.25, 134.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 931)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 405, 1386)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3764)
[M::mem_pestat] mean and std.dev: (758.05, 861.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4953)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 376, 1485)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4013)
[M::mem_pestat] mean and std.dev: (594.69, 668.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5277)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696186 sequences (100000097 bp) in 2.722 CPU sec, 2.987 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 285911, 14, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 314, 879)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2245)
[M::mem_pestat] mean and std.dev: (381.46, 278.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2928)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 247, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 749)
[M::mem_pestat] mean and std.dev: (272.26, 136.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 944)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 512, 848)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2210)
[M::mem_pestat] mean and std.dev: (480.58, 364.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2891)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 419, 1040)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2692)
[M::mem_pestat] mean and std.dev: (597.98, 498.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3518)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697714 reads in 174.487 CPU sec, 5.651 real sec
sorting block 21, #reads = 1084115 mem = 536878040 peak = 941506560
[M::mem_process_seqs] Processed 697334 reads in 116.275 CPU sec, 3.713 real sec
[M::process] read 695462 sequences (100000096 bp) in 2.226 CPU sec, 2.328 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 285559, 26, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 284, 1218)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3262)
[M::mem_pestat] mean and std.dev: (637.43, 762.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4284)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 250, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 751)
[M::mem_pestat] mean and std.dev: (274.30, 136.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 946)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (233, 663, 959)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2411)
[M::mem_pestat] mean and std.dev: (502.86, 355.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3137)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 446, 540)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1186)
[M::mem_pestat] mean and std.dev: (367.80, 198.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1509)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 22, #reads = 1085760 mem = 536879159 peak = 970887168
[M::process] read 694624 sequences (100000091 bp) in 2.732 CPU sec, 3.053 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 284871, 15, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 364, 988)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2600)
[M::mem_pestat] mean and std.dev: (505.65, 476.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3406)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 252, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 759)
[M::mem_pestat] mean and std.dev: (276.62, 137.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 956)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (539, 852, 1600)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3722)
[M::mem_pestat] mean and std.dev: (988.20, 762.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4783)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 330, 511)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1093)
[M::mem_pestat] mean and std.dev: (339.64, 210.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1384)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696186 reads in 176.865 CPU sec, 5.760 real sec
[M::mem_process_seqs] Processed 695462 reads in 120.157 CPU sec, 3.880 real sec
[M::process] read 694758 sequences (100000081 bp) in 2.128 CPU sec, 2.308 real sec...
sorting block 23, #reads = 1084951 mem = 536876247 peak = 970887168
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 284801, 26, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 336, 727)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1843)
[M::mem_pestat] mean and std.dev: (442.04, 396.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2401)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 254, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 760)
[M::mem_pestat] mean and std.dev: (277.92, 137.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 957)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (327, 768, 1181)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2889)
[M::mem_pestat] mean and std.dev: (753.23, 617.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3743)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 330, 459)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 943)
[M::mem_pestat] mean and std.dev: (334.64, 182.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1185)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694546 sequences (100000010 bp) in 2.750 CPU sec, 2.990 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 284478, 24, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 231, 1196)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3266)
[M::mem_pestat] mean and std.dev: (554.39, 585.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4301)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 252, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 753)
[M::mem_pestat] mean and std.dev: (276.13, 136.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 948)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (358, 604, 855)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1849)
[M::mem_pestat] mean and std.dev: (701.61, 465.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2564)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (232, 341, 950)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2386)
[M::mem_pestat] mean and std.dev: (501.12, 431.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3104)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 694624 reads in 177.888 CPU sec, 5.774 real sec
[M::mem_process_seqs] Processed 694758 reads in 121.760 CPU sec, 3.929 real sec
[M::process] read 693866 sequences (100000020 bp) in 2.245 CPU sec, 2.319 real sec...
sorting block 24, #reads = 1082140 mem = 536878555 peak = 970887168
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 283953, 25, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 345, 636)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1524)
[M::mem_pestat] mean and std.dev: (410.98, 351.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1968)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 252, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 751)
[M::mem_pestat] mean and std.dev: (276.13, 136.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 945)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (354, 486, 1018)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2346)
[M::mem_pestat] mean and std.dev: (596.52, 453.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3010)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 254, 455)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1013)
[M::mem_pestat] mean and std.dev: (299.32, 199.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1292)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 693044 sequences (100000209 bp) in 2.622 CPU sec, 2.977 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 284457, 26, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (248, 459, 880)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2144)
[M::mem_pestat] mean and std.dev: (490.87, 416.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2776)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 255, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 755)
[M::mem_pestat] mean and std.dev: (277.71, 135.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 950)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (48, 435, 2294)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6786)
[M::mem_pestat] mean and std.dev: (1065.60, 1364.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9032)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (237, 378, 1055)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2691)
[M::mem_pestat] mean and std.dev: (616.55, 542.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3509)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 694546 reads in 175.052 CPU sec, 5.698 real sec
[M::process] read 692184 sequences (100000301 bp) in 1.757 CPU sec, 1.763 real sec...
sorting block 25, #reads = 1082072 mem = 536879248 peak = 970887168
[M::mem_process_seqs] Processed 693866 reads in 118.708 CPU sec, 3.884 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 283936, 9, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (146, 207, 397)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 899)
[M::mem_pestat] mean and std.dev: (278.85, 188.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1150)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 257, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 751)
[M::mem_pestat] mean and std.dev: (278.67, 135.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 944)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 293, 797)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1971)
[M::mem_pestat] mean and std.dev: (489.07, 449.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2558)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 26, #reads = 1081135 mem = 536884023 peak = 970887168
[M::process] read 702282 sequences (100000277 bp) in 2.955 CPU sec, 3.266 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 283901, 20, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 318, 756)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1964)
[M::mem_pestat] mean and std.dev: (328.78, 255.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2568)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 261, 372)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 768)
[M::mem_pestat] mean and std.dev: (283.26, 138.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 966)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (579, 1301, 5217)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 14493)
[M::mem_pestat] mean and std.dev: (2496.05, 2595.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 19131)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 425, 946)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2404)
[M::mem_pestat] mean and std.dev: (618.16, 571.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3133)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 693044 reads in 172.556 CPU sec, 5.617 real sec
[M::mem_process_seqs] Processed 692184 reads in 115.667 CPU sec, 3.749 real sec
[M::process] read 700844 sequences (100000221 bp) in 2.486 CPU sec, 2.771 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 287542, 19, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 208, 397)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 887)
[M::mem_pestat] mean and std.dev: (270.64, 179.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1132)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 229, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 695)
[M::mem_pestat] mean and std.dev: (255.79, 129.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 875)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (316, 1041, 1305)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3283)
[M::mem_pestat] mean and std.dev: (853.74, 546.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4272)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 272, 526)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1248)
[M::mem_pestat] mean and std.dev: (330.58, 241.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1609)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 27, #reads = 1080588 mem = 536878644 peak = 970887168
[M::process] read 699034 sequences (100000113 bp) in 2.598 CPU sec, 2.987 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 287107, 23, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 226, 407)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 891)
[M::mem_pestat] mean and std.dev: (260.79, 141.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1133)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 234, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 716)
[M::mem_pestat] mean and std.dev: (261.69, 132.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 902)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (241, 622, 1063)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2707)
[M::mem_pestat] mean and std.dev: (663.45, 500.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3529)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 562, 1519)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4183)
[M::mem_pestat] mean and std.dev: (741.87, 737.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5515)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702282 reads in 185.287 CPU sec, 6.035 real sec
[M::mem_process_seqs] Processed 700844 reads in 119.250 CPU sec, 3.853 real sec
[M::process] read 697664 sequences (100000109 bp) in 2.028 CPU sec, 2.213 real sec...
sorting block 28, #reads = 1083327 mem = 536880071 peak = 970887168
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 286802, 13, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 299, 863)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2173)
[M::mem_pestat] mean and std.dev: (456.47, 434.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2828)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 240, 353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 739)
[M::mem_pestat] mean and std.dev: (267.35, 135.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 932)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (67, 219, 694)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1948)
[M::mem_pestat] mean and std.dev: (355.00, 481.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2575)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 344, 706)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1790)
[M::mem_pestat] mean and std.dev: (430.97, 320.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2332)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696792 sequences (100000088 bp) in 2.844 CPU sec, 3.106 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 286329, 21, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 560, 791)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1943)
[M::mem_pestat] mean and std.dev: (485.03, 284.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2519)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 245, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 754)
[M::mem_pestat] mean and std.dev: (272.23, 138.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 951)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (139, 479, 1463)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4111)
[M::mem_pestat] mean and std.dev: (826.25, 848.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5435)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 347, 555)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1261)
[M::mem_pestat] mean and std.dev: (354.62, 213.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1614)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699034 reads in 183.016 CPU sec, 5.887 real sec
[M::process] read 695494 sequences (100000166 bp) in 2.028 CPU sec, 2.123 real sec...
sorting block 29, #reads = 1084258 mem = 536880757 peak = 970887168
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 285353, 20, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 251, 523)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1255)
[M::mem_pestat] mean and std.dev: (292.95, 241.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1621)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 247, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 759)
[M::mem_pestat] mean and std.dev: (274.67, 139.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 957)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (825, 963, 2306)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5268)
[M::mem_pestat] mean and std.dev: (1025.83, 985.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6749)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 366, 715)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1705)
[M::mem_pestat] mean and std.dev: (415.37, 270.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2200)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696792 reads in 106.247 CPU sec, 3.403 real sec
[M::process] read 695436 sequences (100000144 bp) in 2.318 CPU sec, 2.405 real sec...
sorting block 30, #reads = 1082049 mem = 536877644 peak = 970887168
[M::mem_process_seqs] Processed 697664 reads in 267.085 CPU sec, 8.548 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 285085, 20, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 246, 804)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2012)
[M::mem_pestat] mean and std.dev: (395.49, 328.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2616)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 251, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 761)
[M::mem_pestat] mean and std.dev: (276.82, 139.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 959)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (793, 1227, 2106)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4732)
[M::mem_pestat] mean and std.dev: (1263.22, 1122.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6045)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 363, 1555)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4321)
[M::mem_pestat] mean and std.dev: (670.96, 751.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5704)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695018 sequences (100000282 bp) in 2.859 CPU sec, 3.182 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 285339, 14, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 238, 536)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1312)
[M::mem_pestat] mean and std.dev: (276.71, 198.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1700)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 250, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 755)
[M::mem_pestat] mean and std.dev: (275.79, 137.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 951)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (481, 1132, 1826)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4516)
[M::mem_pestat] mean and std.dev: (1171.38, 972.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5861)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 254, 770)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1896)
[M::mem_pestat] mean and std.dev: (313.98, 216.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2459)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695494 reads in 204.484 CPU sec, 6.586 real sec
[M::mem_process_seqs] Processed 695436 reads in 123.962 CPU sec, 3.979 real sec
[M::process] read 694390 sequences (100000238 bp) in 2.140 CPU sec, 2.288 real sec...
sorting block 31, #reads = 1082179 mem = 536878022 peak = 970887168
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 284667, 26, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 239, 673)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1625)
[M::mem_pestat] mean and std.dev: (384.15, 325.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2101)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 251, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 758)
[M::mem_pestat] mean and std.dev: (276.73, 137.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 955)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (338, 950, 2673)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7343)
[M::mem_pestat] mean and std.dev: (1710.60, 1984.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9678)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 249, 526)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1202)
[M::mem_pestat] mean and std.dev: (346.35, 235.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1540)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694230 sequences (100000051 bp) in 2.247 CPU sec, 2.717 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 285056, 23, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 257, 408)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 886)
[M::mem_pestat] mean and std.dev: (264.52, 144.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1125)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 252, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 751)
[M::mem_pestat] mean and std.dev: (275.92, 135.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 945)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (330, 745, 1787)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4701)
[M::mem_pestat] mean and std.dev: (934.23, 906.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6158)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 365, 710)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1760)
[M::mem_pestat] mean and std.dev: (387.63, 294.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2285)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695018 reads in 186.146 CPU sec, 6.036 real sec
sorting block 32, #reads = 1081566 mem = 536879162 peak = 970887168
[M::process] read 700972 sequences (100000028 bp) in 2.082 CPU sec, 2.251 real sec...
[M::mem_process_seqs] Processed 694390 reads in 123.405 CPU sec, 3.951 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 284807, 20, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (136, 208, 449)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1075)
[M::mem_pestat] mean and std.dev: (233.29, 153.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1388)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 253, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 754)
[M::mem_pestat] mean and std.dev: (276.89, 136.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 949)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (141, 409, 434)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1020)
[M::mem_pestat] mean and std.dev: (330.83, 244.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1313)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 276, 998)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2642)
[M::mem_pestat] mean and std.dev: (462.42, 408.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3464)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 33, #reads = 1079485 mem = 536879995 peak = 999653376
[M::process] read 702062 sequences (100000151 bp) in 2.836 CPU sec, 3.182 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 286973, 16, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 263, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 717)
[M::mem_pestat] mean and std.dev: (260.68, 118.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 893)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 233, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 712)
[M::mem_pestat] mean and std.dev: (260.25, 131.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 897)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (446, 1132, 2506)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6626)
[M::mem_pestat] mean and std.dev: (1377.50, 944.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8686)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 293, 568)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1368)
[M::mem_pestat] mean and std.dev: (357.50, 285.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1768)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701002 sequences (100000208 bp) in 1.860 CPU sec, 1.896 real sec...
[M::mem_process_seqs] Processed 694230 reads in 190.580 CPU sec, 6.159 real sec
[M::mem_process_seqs] Processed 700972 reads in 127.622 CPU sec, 4.097 real sec
sorting block 34, #reads = 1078402 mem = 536878891 peak = 999653376
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 287731, 9, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 261, 523)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1195)
[M::mem_pestat] mean and std.dev: (297.02, 175.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1531)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 230, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 699)
[M::mem_pestat] mean and std.dev: (256.80, 129.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 880)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 426, 1302)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3478)
[M::mem_pestat] mean and std.dev: (717.70, 700.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4566)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 699446 sequences (100000176 bp) in 2.971 CPU sec, 3.376 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 287066, 21, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (142, 238, 661)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1699)
[M::mem_pestat] mean and std.dev: (391.95, 362.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2218)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 233, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 709)
[M::mem_pestat] mean and std.dev: (259.59, 130.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 893)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (895, 1058, 2688)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6274)
[M::mem_pestat] mean and std.dev: (1542.52, 1140.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8067)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 335, 851)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2139)
[M::mem_pestat] mean and std.dev: (446.60, 340.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2783)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698174 sequences (100000195 bp) in 2.025 CPU sec, 2.038 real sec...
[M::mem_process_seqs] Processed 702062 reads in 192.615 CPU sec, 6.216 real sec
sorting block 35, #reads = 1082200 mem = 536879732 peak = 999653376
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 287142, 19, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 219, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 667)
[M::mem_pestat] mean and std.dev: (240.78, 107.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 829)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 238, 349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 727)
[M::mem_pestat] mean and std.dev: (264.69, 133.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 916)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (506, 775, 1542)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3614)
[M::mem_pestat] mean and std.dev: (835.94, 788.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4650)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 405, 552)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1318)
[M::mem_pestat] mean and std.dev: (345.48, 213.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1701)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696584 sequences (100000070 bp) in 2.286 CPU sec, 2.340 real sec...
[M::mem_process_seqs] Processed 699446 reads in 112.934 CPU sec, 3.867 real sec
[M::mem_process_seqs] Processed 701002 reads in 294.336 CPU sec, 9.738 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 286306, 24, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 280, 476)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1116)
[M::mem_pestat] mean and std.dev: (350.02, 244.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1436)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 242, 355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 741)
[M::mem_pestat] mean and std.dev: (269.12, 135.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 934)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 897, 1648)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4568)
[M::mem_pestat] mean and std.dev: (1058.83, 1126.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6028)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 344, 882)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2232)
[M::mem_pestat] mean and std.dev: (419.67, 347.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2907)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 36, #reads = 1083089 mem = 536882320 peak = 999653376
[M::process] read 696186 sequences (100000154 bp) in 2.702 CPU sec, 2.946 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 285727, 23, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 348, 555)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1297)
[M::mem_pestat] mean and std.dev: (346.13, 245.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1668)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 247, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 756)
[M::mem_pestat] mean and std.dev: (273.92, 137.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 953)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (527, 727, 1729)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4133)
[M::mem_pestat] mean and std.dev: (1028.43, 871.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5335)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 384, 550)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1308)
[M::mem_pestat] mean and std.dev: (306.26, 155.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1687)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698174 reads in 205.138 CPU sec, 6.615 real sec
[M::mem_process_seqs] Processed 696584 reads in 124.873 CPU sec, 3.989 real sec
[M::process] read 695360 sequences (100000270 bp) in 2.086 CPU sec, 2.207 real sec...
sorting block 37, #reads = 1081246 mem = 536876869 peak = 999653376
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 285301, 20, 77)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 372, 527)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1153)
[M::mem_pestat] mean and std.dev: (365.15, 250.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1466)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 248, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 751)
[M::mem_pestat] mean and std.dev: (274.23, 137.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 946)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (724, 1153, 2547)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6193)
[M::mem_pestat] mean and std.dev: (1414.42, 954.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8016)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 260, 726)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1812)
[M::mem_pestat] mean and std.dev: (359.37, 265.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2355)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695100 sequences (100000035 bp) in 2.178 CPU sec, 2.612 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 284843, 26, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (253, 370, 659)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1471)
[M::mem_pestat] mean and std.dev: (473.51, 344.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1877)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 250, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 758)
[M::mem_pestat] mean and std.dev: (276.16, 138.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 955)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (538, 1204, 2178)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5458)
[M::mem_pestat] mean and std.dev: (1123.61, 962.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7098)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 349, 715)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1729)
[M::mem_pestat] mean and std.dev: (397.06, 289.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2236)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696186 reads in 186.479 CPU sec, 6.045 real sec
[M::process] read 694764 sequences (100000119 bp) in 2.316 CPU sec, 2.431 real sec...
[M::mem_process_seqs] Processed 695360 reads in 127.106 CPU sec, 4.087 real sec
sorting block 38, #reads = 1079601 mem = 536879563 peak = 999653376
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 284577, 16, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 245, 427)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 883)
[M::mem_pestat] mean and std.dev: (274.06, 160.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1111)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 251, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 762)
[M::mem_pestat] mean and std.dev: (278.06, 140.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 960)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (388, 507, 1480)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3664)
[M::mem_pestat] mean and std.dev: (995.69, 961.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4840)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 274, 562)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1248)
[M::mem_pestat] mean and std.dev: (343.41, 204.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1591)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 39, #reads = 1080067 mem = 536880370 peak = 1003372544
[M::process] read 701276 sequences (100000150 bp) in 2.913 CPU sec, 3.326 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 284517, 20, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 343, 603)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1445)
[M::mem_pestat] mean and std.dev: (328.10, 220.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1866)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 253, 370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 774)
[M::mem_pestat] mean and std.dev: (280.26, 141.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 976)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (455, 1001, 1986)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5048)
[M::mem_pestat] mean and std.dev: (845.65, 624.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6579)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (248, 409, 1410)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3734)
[M::mem_pestat] mean and std.dev: (682.08, 765.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4896)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695100 reads in 187.337 CPU sec, 6.031 real sec
[M::process] read 699998 sequences (100000185 bp) in 1.876 CPU sec, 1.886 real sec...
[M::mem_process_seqs] Processed 694764 reads in 130.072 CPU sec, 4.150 real sec
sorting block 40, #reads = 1079026 mem = 536877551 peak = 1003372544
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 287061, 27, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 316, 544)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1276)
[M::mem_pestat] mean and std.dev: (316.87, 187.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1642)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 232, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 705)
[M::mem_pestat] mean and std.dev: (258.46, 130.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 888)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (282, 922, 2533)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7035)
[M::mem_pestat] mean and std.dev: (1305.59, 1162.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9286)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 319, 712)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1746)
[M::mem_pestat] mean and std.dev: (386.71, 272.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2263)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699020 sequences (100000001 bp) in 2.994 CPU sec, 3.254 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 287134, 27, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 295, 427)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 871)
[M::mem_pestat] mean and std.dev: (255.67, 86.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1093)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 237, 345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 717)
[M::mem_pestat] mean and std.dev: (262.73, 131.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 903)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (309, 582, 1109)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2709)
[M::mem_pestat] mean and std.dev: (611.48, 431.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3509)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (233, 294, 1004)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2546)
[M::mem_pestat] mean and std.dev: (559.93, 467.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3317)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698320 sequences (100000212 bp) in 2.000 CPU sec, 2.014 real sec...
[M::mem_process_seqs] Processed 701276 reads in 191.828 CPU sec, 6.135 real sec
[M::mem_process_seqs] Processed 699998 reads in 123.490 CPU sec, 3.942 real sec
sorting block 41, #reads = 1077775 mem = 536876933 peak = 1003372544
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 286459, 22, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 271, 565)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1327)
[M::mem_pestat] mean and std.dev: (300.91, 214.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1708)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 240, 349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 727)
[M::mem_pestat] mean and std.dev: (265.60, 133.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 916)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 305, 1133)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2965)
[M::mem_pestat] mean and std.dev: (574.68, 556.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3881)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 403, 666)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1542)
[M::mem_pestat] mean and std.dev: (400.57, 207.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1980)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697640 sequences (100000058 bp) in 2.787 CPU sec, 3.082 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 286363, 16, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 257, 792)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2040)
[M::mem_pestat] mean and std.dev: (494.32, 522.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2664)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 242, 355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 741)
[M::mem_pestat] mean and std.dev: (269.10, 135.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 934)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 671, 992)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2586)
[M::mem_pestat] mean and std.dev: (555.07, 394.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3383)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 326, 512)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1100)
[M::mem_pestat] mean and std.dev: (312.15, 170.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1394)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696586 sequences (100000193 bp) in 1.934 CPU sec, 1.940 real sec...
[M::mem_process_seqs] Processed 699020 reads in 183.224 CPU sec, 5.895 real sec
[M::mem_process_seqs] Processed 698320 reads in 120.637 CPU sec, 3.855 real sec
sorting block 42, #reads = 1085117 mem = 536881502 peak = 1003372544
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 286658, 16, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 190, 484)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1146)
[M::mem_pestat] mean and std.dev: (275.44, 205.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1477)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 245, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 748)
[M::mem_pestat] mean and std.dev: (271.29, 136.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 943)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (285, 1047, 1324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3402)
[M::mem_pestat] mean and std.dev: (934.60, 828.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4441)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 297, 726)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1786)
[M::mem_pestat] mean and std.dev: (461.74, 380.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2316)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695394 sequences (100000299 bp) in 2.983 CPU sec, 3.513 real sec...
sorting block 43, #reads = 1083499 mem = 536878246 peak = 1003372544
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 285895, 8, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 284, 755)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1911)
[M::mem_pestat] mean and std.dev: (355.00, 300.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2489)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 248, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 756)
[M::mem_pestat] mean and std.dev: (274.39, 138.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 953)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 313, 552)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1272)
[M::mem_pestat] mean and std.dev: (376.21, 253.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1632)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697640 reads in 191.329 CPU sec, 6.192 real sec
[M::process] read 695100 sequences (100000169 bp) in 1.840 CPU sec, 1.947 real sec...
[M::mem_process_seqs] Processed 696586 reads in 123.597 CPU sec, 4.006 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 284715, 27, 74)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 329, 578)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1328)
[M::mem_pestat] mean and std.dev: (373.28, 253.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1703)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 251, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 758)
[M::mem_pestat] mean and std.dev: (276.42, 138.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 955)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (435, 706, 1527)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3711)
[M::mem_pestat] mean and std.dev: (956.81, 780.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4803)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 334, 746)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1842)
[M::mem_pestat] mean and std.dev: (447.73, 440.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2390)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 44, #reads = 1082816 mem = 536880425 peak = 1003372544
[M::process] read 695118 sequences (100000295 bp) in 3.063 CPU sec, 3.509 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 285008, 13, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 263, 1042)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2790)
[M::mem_pestat] mean and std.dev: (483.09, 442.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3664)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 250, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 755)
[M::mem_pestat] mean and std.dev: (275.53, 137.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 951)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (247, 545, 1285)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3361)
[M::mem_pestat] mean and std.dev: (844.08, 930.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4566)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 294, 405)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 853)
[M::mem_pestat] mean and std.dev: (292.79, 163.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1077)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695394 reads in 193.858 CPU sec, 6.309 real sec
[M::process] read 694916 sequences (100000136 bp) in 1.974 CPU sec, 2.032 real sec...
[M::mem_process_seqs] Processed 695100 reads in 127.826 CPU sec, 4.118 real sec
sorting block 45, #reads = 1079150 mem = 536879303 peak = 1003372544
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 284745, 19, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 311, 512)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1102)
[M::mem_pestat] mean and std.dev: (331.83, 162.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1397)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 251, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 758)
[M::mem_pestat] mean and std.dev: (276.38, 137.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 955)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 671, 2285)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6487)
[M::mem_pestat] mean and std.dev: (1278.39, 1659.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8588)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 236, 398)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 868)
[M::mem_pestat] mean and std.dev: (263.53, 158.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1103)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703308 sequences (100000197 bp) in 3.051 CPU sec, 3.464 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 284440, 25, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (140, 270, 519)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1277)
[M::mem_pestat] mean and std.dev: (339.62, 283.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1656)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 250, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 753)
[M::mem_pestat] mean and std.dev: (276.24, 138.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 948)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (128, 376, 570)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1454)
[M::mem_pestat] mean and std.dev: (354.61, 247.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1896)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 253, 759)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1953)
[M::mem_pestat] mean and std.dev: (450.39, 468.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2550)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695118 reads in 202.302 CPU sec, 6.604 real sec
[M::process] read 702828 sequences (100000175 bp) in 2.088 CPU sec, 2.113 real sec...
[M::mem_process_seqs] Processed 694916 reads in 134.690 CPU sec, 4.411 real sec
sorting block 46, #reads = 1078485 mem = 536878305 peak = 1003372544
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 287801, 13, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 307, 634)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1576)
[M::mem_pestat] mean and std.dev: (413.21, 340.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2047)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 226, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 685)
[M::mem_pestat] mean and std.dev: (252.58, 127.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 862)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (531, 1351, 1848)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4482)
[M::mem_pestat] mean and std.dev: (1255.38, 925.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5799)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 307, 539)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1199)
[M::mem_pestat] mean and std.dev: (342.22, 245.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1529)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702736 sequences (100000085 bp) in 2.957 CPU sec, 3.490 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 287965, 16, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 337, 1908)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5368)
[M::mem_pestat] mean and std.dev: (920.26, 1015.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7098)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 228, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 691)
[M::mem_pestat] mean and std.dev: (254.30, 127.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 870)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (259, 559, 654)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1444)
[M::mem_pestat] mean and std.dev: (485.25, 264.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1839)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 288, 404)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 830)
[M::mem_pestat] mean and std.dev: (292.43, 131.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1043)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701196 sequences (100000265 bp) in 1.845 CPU sec, 1.924 real sec...
[M::mem_process_seqs] Processed 703308 reads in 205.029 CPU sec, 6.685 real sec
sorting block 47, #reads = 1076437 mem = 536879785 peak = 1003372544
[M::mem_process_seqs] Processed 702828 reads in 130.647 CPU sec, 4.261 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 287977, 15, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 234, 625)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1511)
[M::mem_pestat] mean and std.dev: (378.30, 287.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1954)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 227, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 688)
[M::mem_pestat] mean and std.dev: (253.64, 127.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 866)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (646, 1745, 2728)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6892)
[M::mem_pestat] mean and std.dev: (1908.71, 1911.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9554)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 308, 505)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1101)
[M::mem_pestat] mean and std.dev: (312.96, 179.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1399)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 48, #reads = 1081749 mem = 536877689 peak = 1059201024
[M::process] read 699174 sequences (100000165 bp) in 2.585 CPU sec, 2.908 real sec...
[M::process] read 696908 sequences (100000157 bp) in 2.009 CPU sec, 2.019 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 287431, 27, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 337, 1060)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2740)
[M::mem_pestat] mean and std.dev: (522.74, 519.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3580)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 232, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 706)
[M::mem_pestat] mean and std.dev: (259.06, 131.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 889)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (132, 525, 1929)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5523)
[M::mem_pestat] mean and std.dev: (1114.81, 1342.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7320)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 263, 371)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 743)
[M::mem_pestat] mean and std.dev: (280.50, 144.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 929)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702736 reads in 199.889 CPU sec, 6.442 real sec
[M::mem_process_seqs] Processed 701196 reads in 129.363 CPU sec, 4.162 real sec
sorting block 49, #reads = 1080679 mem = 536886488 peak = 1059201024
[M::process] read 695918 sequences (100000058 bp) in 2.867 CPU sec, 3.274 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 285957, 29, 76)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 223, 549)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1351)
[M::mem_pestat] mean and std.dev: (339.35, 285.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1752)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 245, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 746)
[M::mem_pestat] mean and std.dev: (272.18, 137.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 940)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (133, 484, 1935)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5539)
[M::mem_pestat] mean and std.dev: (877.30, 1201.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7341)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 330, 720)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1792)
[M::mem_pestat] mean and std.dev: (416.63, 311.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2328)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694924 sequences (100000035 bp) in 1.908 CPU sec, 1.920 real sec...
[M::mem_process_seqs] Processed 696908 reads in 113.017 CPU sec, 3.600 real sec
sorting block 50, #reads = 1080688 mem = 536880018 peak = 1059201024
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 286492, 19, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 265, 567)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1367)
[M::mem_pestat] mean and std.dev: (369.35, 260.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1767)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 239, 351)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 733)
[M::mem_pestat] mean and std.dev: (266.56, 135.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 924)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (391, 581, 1065)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2413)
[M::mem_pestat] mean and std.dev: (634.39, 342.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3087)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 298, 432)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 908)
[M::mem_pestat] mean and std.dev: (299.05, 135.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1146)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 285457, 14, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 311, 608)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1422)
[M::mem_pestat] mean and std.dev: (372.52, 272.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1829)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 247, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 748)
[M::mem_pestat] mean and std.dev: (273.53, 137.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 942)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (397, 555, 745)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1441)
[M::mem_pestat] mean and std.dev: (479.92, 241.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1789)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 238, 571)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1387)
[M::mem_pestat] mean and std.dev: (361.25, 260.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1795)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699174 reads in 304.262 CPU sec, 9.828 real sec
[M::mem_process_seqs] Processed 695918 reads in 150.360 CPU sec, 4.977 real sec
[M::process] read 693994 sequences (100000278 bp) in 2.320 CPU sec, 2.497 real sec...
sorting block 51, #reads = 1078594 mem = 536879332 peak = 1059201024
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 285156, 21, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 291, 762)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1980)
[M::mem_pestat] mean and std.dev: (479.61, 421.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2589)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 250, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 755)
[M::mem_pestat] mean and std.dev: (275.90, 137.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 951)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 488, 1014)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2718)
[M::mem_pestat] mean and std.dev: (487.79, 388.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3570)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 362, 536)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1178)
[M::mem_pestat] mean and std.dev: (360.51, 205.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1499)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 592736 sequences (85393992 bp) in 2.419 CPU sec, 2.717 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 284984, 18, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 289, 660)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1648)
[M::mem_pestat] mean and std.dev: (342.32, 280.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2142)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 253, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 763)
[M::mem_pestat] mean and std.dev: (278.57, 138.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 961)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 281, 2437)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6995)
[M::mem_pestat] mean and std.dev: (737.20, 1342.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9274)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 245, 487)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1105)
[M::mem_pestat] mean and std.dev: (312.80, 183.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1414)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 694924 reads in 182.209 CPU sec, 5.953 real sec
[M::mem_process_seqs] Processed 693994 reads in 119.833 CPU sec, 3.964 real sec
sorting block 52, #reads = 1079493 mem = 536879862 peak = 1059201024
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 243132, 11, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 313, 659)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1599)
[M::mem_pestat] mean and std.dev: (396.51, 322.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2069)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 254, 369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 769)
[M::mem_pestat] mean and std.dev: (279.92, 139.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 969)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 366, 1184)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3168)
[M::mem_pestat] mean and std.dev: (572.45, 497.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4160)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 194, 345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 727)
[M::mem_pestat] mean and std.dev: (214.43, 103.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 918)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 592736 reads in 89.383 CPU sec, 3.100 real sec
sorting block 53, #reads = 1080562 mem = 536878396 peak = 1080631296
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000a06d1
  features: 1f8bfbff fffab20b
  extended: f1bf27eb 1b407f7e
  amd bits: 2c100800 00000121
     brand: Intel(R) Xeon(R) 6975P-C
threads: 31
algo: bwa-mem
license: sentieon:klib=31
reads: 58391440
overall: 70055223296 mem 10134.463 user 318.923 sys 353.690 real
[main] Version: 0.7.17-r1188
[main] CMD: /opt/conda/share/sentieon-202308.03-3/libexec/bwa mem -K 100000000 -Y -R @RG\tID:A23MHWWLT4.1136_5TB-T1-TDNA-1_A23MHWWLT4_1.L002\tPU:L002\tSM:1136_5TB-T1-TDNA-1_A23MHWWLT4_1\tLB:1136_5TB-T1-TDNA-1_A23MHWWLT4_1\tDS:s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta\tPL:ILLUMINA -t 31 ./BWAIndex/Homo_sapiens_assembly38.fasta.64 0004.1136_5TB-T1-TDNA-1_A23MHWWLT4_1_R1.fastq.gz 0004.1136_5TB-T1-TDNA-1_A23MHWWLT4_1_R2.fastq.gz
[main] Real time: 353.727 sec; CPU: 10453.389 sec
sorting block 54, #reads = 358152 mem = 178405275 peak = 1080631296
uniq header count 1
merging 55 blocks
sw version: sentieon-genomics-202308.03
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000a06d1
  features: 1f8bfbff fffab20b
  extended: f1bf27eb 1b407f7e
  amd bits: 2c100800 00000121
     brand: Intel(R) Xeon(R) 6975P-C
threads: 31 max 192
algo: util-sort
license: sentieon:util=1
output file size: 3317526326
output reads: 58773199
bam_mem_sort: 55 calls 38.138 user 1.080 sys 41.555 real
bam_write: 55 calls 35.306 user 2.458 sys 77.713 real
execute: 1 calls 18.565 user 1.239 sys 376.580 real
merge_files: 1 calls 18.558 user 1.201 sys 22.609 real
parse_chunk: 870 calls 39.542 user 11.460 sys 67.267 real
read_chunk: 2351 calls 20.230 user 13.090 sys 289.491 real
sort_block: 1 calls 13.422 user 12.131 sys 278.286 real
write_chunk: 1479 calls 18.162 user 1.005 sys 21.729 real
overall: 2759958528 mem 827.214 user 40.036 sys 376.601 real
ls: cannot access '*.cram': No such file or directory