This software is licensed to bgold@natera.com by Sentieon Inc.
cmdline: /opt/conda/share/sentieon-202308.03-3/libexec/util sort -r Homo_sapiens_assembly38.fasta -t 31 -o 1136_4GR-T1-TDNA-1_A23MHWWLT4_1.bam --sam2bam -
This software is licensed to bgold@natera.com by Sentieon Inc.
version: sentieon-genomics-202308.03
[M::bwa_idx_load_from_disk] read 3171 ALT contigs
[M::main_mem] bwa index loaded in 2090.258 CPU sec, 92.696 real sec
[M::process] read 701070 sequences (100000037 bp) in 1.632 CPU sec, 1.636 real sec...
[M::process] read 700316 sequences (100000116 bp) in 1.974 CPU sec, 2.444 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 285502, 12, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (144, 248, 959)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2589)
[M::mem_pestat] mean and std.dev: (365.29, 378.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3404)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 232, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 717)
[M::mem_pestat] mean and std.dev: (259.94, 132.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 904)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (427, 587, 1607)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3967)
[M::mem_pestat] mean and std.dev: (1059.83, 969.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5147)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 304, 915)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2331)
[M::mem_pestat] mean and std.dev: (469.78, 355.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3039)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700432 sequences (100000150 bp) in 2.074 CPU sec, 2.208 real sec...
[M::process] read 699604 sequences (100000080 bp) in 2.171 CPU sec, 2.386 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 285060, 21, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 285, 562)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1366)
[M::mem_pestat] mean and std.dev: (302.69, 234.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1768)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 235, 347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 725)
[M::mem_pestat] mean and std.dev: (263.10, 133.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 914)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 564, 1164)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3144)
[M::mem_pestat] mean and std.dev: (525.00, 480.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4134)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (250, 493, 967)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2401)
[M::mem_pestat] mean and std.dev: (674.47, 610.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3118)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701070 reads in 235.359 CPU sec, 8.499 real sec
[M::mem_process_seqs] Processed 700316 reads in 152.364 CPU sec, 5.448 real sec
sorting block 0, #reads = 1079098 mem = 536883383 peak = 550420480
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 285487, 23, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (286, 596, 2518)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6982)
[M::mem_pestat] mean and std.dev: (1156.07, 1212.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9214)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 234, 346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 724)
[M::mem_pestat] mean and std.dev: (262.15, 133.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 913)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (236, 585, 933)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2327)
[M::mem_pestat] mean and std.dev: (593.14, 396.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3024)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (243, 617, 1103)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2823)
[M::mem_pestat] mean and std.dev: (666.66, 578.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3683)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698638 sequences (100000097 bp) in 2.609 CPU sec, 2.856 real sec...
[M::process] read 698200 sequences (100000285 bp) in 2.042 CPU sec, 2.081 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 284780, 30, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 324, 777)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1979)
[M::mem_pestat] mean and std.dev: (432.44, 338.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2580)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 237, 349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 729)
[M::mem_pestat] mean and std.dev: (265.03, 135.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 919)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (91, 482, 896)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2506)
[M::mem_pestat] mean and std.dev: (486.62, 445.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3311)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 832, 1814)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5106)
[M::mem_pestat] mean and std.dev: (881.20, 1036.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6752)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700432 reads in 225.773 CPU sec, 7.597 real sec
[M::mem_process_seqs] Processed 699604 reads in 155.185 CPU sec, 5.280 real sec
sorting block 1, #reads = 1077591 mem = 536881159 peak = 682733568
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 284388, 23, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (331, 676, 1400)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3538)
[M::mem_pestat] mean and std.dev: (650.89, 457.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4607)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 239, 352)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 736)
[M::mem_pestat] mean and std.dev: (267.27, 136.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 928)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (421, 587, 1009)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2185)
[M::mem_pestat] mean and std.dev: (501.33, 289.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2773)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (241, 519, 1034)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2620)
[M::mem_pestat] mean and std.dev: (592.53, 472.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3413)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697378 sequences (100000071 bp) in 2.515 CPU sec, 2.740 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 284124, 26, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 344, 948)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2444)
[M::mem_pestat] mean and std.dev: (492.75, 451.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3192)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 240, 356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 746)
[M::mem_pestat] mean and std.dev: (269.66, 138.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 941)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (534, 1033, 1983)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4881)
[M::mem_pestat] mean and std.dev: (1014.10, 979.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6330)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (255, 322, 711)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1623)
[M::mem_pestat] mean and std.dev: (372.38, 222.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2079)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697502 sequences (100000268 bp) in 2.177 CPU sec, 2.262 real sec...
[M::mem_process_seqs] Processed 698638 reads in 224.163 CPU sec, 7.333 real sec
[M::mem_process_seqs] Processed 698200 reads in 156.353 CPU sec, 5.114 real sec
sorting block 2, #reads = 1077821 mem = 536878139 peak = 820154368
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 283998, 35, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 552, 1487)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4045)
[M::mem_pestat] mean and std.dev: (701.00, 544.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5324)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 244, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 762)
[M::mem_pestat] mean and std.dev: (273.64, 140.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 962)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (320, 762, 3405)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9575)
[M::mem_pestat] mean and std.dev: (1985.54, 2737.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12937)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 361, 1235)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3343)
[M::mem_pestat] mean and std.dev: (588.19, 618.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4397)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697174 sequences (100000014 bp) in 3.090 CPU sec, 3.335 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 283913, 26, 22)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 678, 1450)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4010)
[M::mem_pestat] mean and std.dev: (773.75, 764.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5290)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 245, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 763)
[M::mem_pestat] mean and std.dev: (274.55, 141.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 963)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (303, 497, 1135)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2799)
[M::mem_pestat] mean and std.dev: (797.85, 733.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3731)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 278, 767)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1931)
[M::mem_pestat] mean and std.dev: (334.56, 290.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2513)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696494 sequences (100000021 bp) in 2.354 CPU sec, 2.397 real sec...
[M::mem_process_seqs] Processed 697378 reads in 217.322 CPU sec, 7.123 real sec
sorting block 3, #reads = 1077665 mem = 536879156 peak = 820154368
[M::mem_process_seqs] Processed 697502 reads in 151.439 CPU sec, 4.975 real sec
sorting block 4, #reads = 1076975 mem = 536882477 peak = 840769536
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 283833, 34, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 271, 390)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 846)
[M::mem_pestat] mean and std.dev: (238.24, 108.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1074)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 245, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 769)
[M::mem_pestat] mean and std.dev: (275.54, 142.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 971)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 402, 1556)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4252)
[M::mem_pestat] mean and std.dev: (938.29, 1109.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5600)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (264, 696, 1980)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5412)
[M::mem_pestat] mean and std.dev: (1103.12, 1230.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7128)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696532 sequences (100000230 bp) in 2.513 CPU sec, 2.720 real sec...
[M::process] read 696564 sequences (100000259 bp) in 2.130 CPU sec, 2.158 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 283527, 35, 21)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (243, 374, 815)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1959)
[M::mem_pestat] mean and std.dev: (483.89, 365.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2531)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 246, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 764)
[M::mem_pestat] mean and std.dev: (275.23, 141.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 964)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (279, 956, 2569)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7149)
[M::mem_pestat] mean and std.dev: (1820.86, 1963.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9676)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 417, 849)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2149)
[M::mem_pestat] mean and std.dev: (516.47, 440.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2799)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697174 reads in 220.626 CPU sec, 7.172 real sec
[M::mem_process_seqs] Processed 696494 reads in 152.499 CPU sec, 4.962 real sec
sorting block 5, #reads = 1077265 mem = 536884479 peak = 840769536
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 283011, 22, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (247, 459, 1398)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3700)
[M::mem_pestat] mean and std.dev: (604.50, 624.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4851)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 245, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 760)
[M::mem_pestat] mean and std.dev: (274.37, 140.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 959)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (428, 1342, 1832)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4640)
[M::mem_pestat] mean and std.dev: (1391.50, 1124.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6044)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (284, 400, 525)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1007)
[M::mem_pestat] mean and std.dev: (349.96, 129.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1248)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696182 sequences (100000121 bp) in 2.972 CPU sec, 3.223 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 283099, 28, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 526, 1596)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4364)
[M::mem_pestat] mean and std.dev: (760.69, 781.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5748)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 246, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 755)
[M::mem_pestat] mean and std.dev: (273.90, 139.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 952)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 418, 2075)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5833)
[M::mem_pestat] mean and std.dev: (959.15, 1163.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7712)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 777, 1545)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4201)
[M::mem_pestat] mean and std.dev: (715.42, 671.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5529)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696510 sequences (100000005 bp) in 2.440 CPU sec, 2.501 real sec...
[M::mem_process_seqs] Processed 696532 reads in 223.901 CPU sec, 7.344 real sec
[M::mem_process_seqs] Processed 696564 reads in 154.779 CPU sec, 5.085 real sec
sorting block 6, #reads = 1075910 mem = 536880466 peak = 840769536
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 283329, 33, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (230, 444, 2322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6506)
[M::mem_pestat] mean and std.dev: (1091.54, 1359.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8598)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 246, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 758)
[M::mem_pestat] mean and std.dev: (273.89, 139.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 956)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (251, 418, 1407)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3719)
[M::mem_pestat] mean and std.dev: (631.80, 604.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4875)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 292, 544)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1192)
[M::mem_pestat] mean and std.dev: (369.50, 251.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1516)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696422 sequences (100000189 bp) in 3.001 CPU sec, 3.226 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 283157, 30, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (287, 353, 1060)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2606)
[M::mem_pestat] mean and std.dev: (558.74, 501.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3379)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 244, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 751)
[M::mem_pestat] mean and std.dev: (272.54, 138.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 947)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (59, 1166, 2005)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5897)
[M::mem_pestat] mean and std.dev: (1134.90, 1177.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7843)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (254, 321, 1017)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2543)
[M::mem_pestat] mean and std.dev: (576.33, 518.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3306)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696182 reads in 207.537 CPU sec, 6.682 real sec
[M::process] read 696530 sequences (100000159 bp) in 2.261 CPU sec, 2.321 real sec...
sorting block 7, #reads = 1075612 mem = 536878847 peak = 840769536
[M::mem_process_seqs] Processed 696510 reads in 144.254 CPU sec, 4.622 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 283526, 22, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (358, 751, 2228)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5968)
[M::mem_pestat] mean and std.dev: (1195.58, 1530.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7838)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 244, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 754)
[M::mem_pestat] mean and std.dev: (272.92, 139.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 951)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (419, 885, 1586)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3920)
[M::mem_pestat] mean and std.dev: (956.62, 705.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5087)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (287, 561, 1218)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3080)
[M::mem_pestat] mean and std.dev: (815.10, 717.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4011)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 8, #reads = 1076990 mem = 536878125 peak = 840769536
[M::process] read 695904 sequences (100000146 bp) in 3.523 CPU sec, 3.746 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 283190, 29, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (310, 539, 577)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1111)
[M::mem_pestat] mean and std.dev: (413.74, 194.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1378)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 245, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 755)
[M::mem_pestat] mean and std.dev: (273.69, 140.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 952)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (597, 1288, 5060)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13986)
[M::mem_pestat] mean and std.dev: (2054.90, 1972.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 18449)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 471, 1100)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2936)
[M::mem_pestat] mean and std.dev: (569.24, 433.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3854)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696422 reads in 207.557 CPU sec, 6.723 real sec
[M::mem_process_seqs] Processed 696530 reads in 146.520 CPU sec, 4.675 real sec
[M::process] read 695806 sequences (100000010 bp) in 2.680 CPU sec, 2.802 real sec...
sorting block 9, #reads = 1075140 mem = 536878773 peak = 840769536
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 283158, 17, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 397, 982)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2634)
[M::mem_pestat] mean and std.dev: (440.34, 427.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3460)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 246, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 758)
[M::mem_pestat] mean and std.dev: (274.65, 140.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 956)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 557, 2771)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8009)
[M::mem_pestat] mean and std.dev: (1211.38, 1629.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10628)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (313, 1028, 2861)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7957)
[M::mem_pestat] mean and std.dev: (1366.79, 1176.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10505)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695540 sequences (100000106 bp) in 2.865 CPU sec, 3.109 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 283378, 24, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 539, 1951)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5431)
[M::mem_pestat] mean and std.dev: (1060.81, 1110.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7171)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 247, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 759)
[M::mem_pestat] mean and std.dev: (275.64, 140.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 957)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (414, 643, 1178)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2706)
[M::mem_pestat] mean and std.dev: (701.43, 446.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3470)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 370, 768)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1860)
[M::mem_pestat] mean and std.dev: (521.43, 452.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2406)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695904 reads in 201.753 CPU sec, 6.493 real sec
[M::process] read 695226 sequences (100000050 bp) in 2.161 CPU sec, 2.184 real sec...
[M::mem_process_seqs] Processed 695806 reads in 142.028 CPU sec, 4.602 real sec
sorting block 10, #reads = 1075536 mem = 536879574 peak = 840769536
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 283211, 26, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 447, 827)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2069)
[M::mem_pestat] mean and std.dev: (413.21, 256.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2690)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 249, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 763)
[M::mem_pestat] mean and std.dev: (276.55, 140.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 962)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 913, 1403)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3837)
[M::mem_pestat] mean and std.dev: (910.17, 926.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5054)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 265, 425)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 927)
[M::mem_pestat] mean and std.dev: (292.58, 176.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1178)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694980 sequences (100000169 bp) in 3.161 CPU sec, 3.441 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 283094, 19, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (244, 432, 748)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1756)
[M::mem_pestat] mean and std.dev: (507.68, 384.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2260)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 250, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 763)
[M::mem_pestat] mean and std.dev: (277.10, 140.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 962)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 710, 1538)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4276)
[M::mem_pestat] mean and std.dev: (998.42, 1007.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5645)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (260, 288, 901)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2183)
[M::mem_pestat] mean and std.dev: (459.00, 395.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2824)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695540 reads in 197.390 CPU sec, 6.360 real sec
[M::process] read 694768 sequences (100000177 bp) in 2.468 CPU sec, 2.519 real sec...
sorting block 11, #reads = 1076330 mem = 536880359 peak = 840769536
[M::mem_process_seqs] Processed 695226 reads in 138.961 CPU sec, 4.436 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 282846, 13, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (263, 487, 1349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3521)
[M::mem_pestat] mean and std.dev: (713.97, 685.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4607)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 250, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 769)
[M::mem_pestat] mean and std.dev: (278.06, 141.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 970)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (604, 1157, 2482)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6238)
[M::mem_pestat] mean and std.dev: (1282.58, 882.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8116)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (360, 656, 2317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6231)
[M::mem_pestat] mean and std.dev: (1299.71, 1378.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8188)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694698 sequences (100000161 bp) in 2.801 CPU sec, 3.039 real sec...
sorting block 12, #reads = 1076866 mem = 536886393 peak = 840769536
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 282997, 21, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 218, 913)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2417)
[M::mem_pestat] mean and std.dev: (538.34, 560.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3169)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 253, 370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 776)
[M::mem_pestat] mean and std.dev: (279.64, 141.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 979)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (483, 1424, 3769)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10341)
[M::mem_pestat] mean and std.dev: (2579.76, 3223.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 15473)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 433, 1017)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2695)
[M::mem_pestat] mean and std.dev: (618.34, 617.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3534)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 694980 reads in 201.335 CPU sec, 6.544 real sec
[M::process] read 694232 sequences (100000173 bp) in 2.256 CPU sec, 2.306 real sec...
[M::mem_process_seqs] Processed 694768 reads in 142.956 CPU sec, 4.640 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 282808, 29, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 327, 894)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2268)
[M::mem_pestat] mean and std.dev: (641.79, 677.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3354)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 254, 372)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 780)
[M::mem_pestat] mean and std.dev: (281.40, 143.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 984)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (301, 611, 1150)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2848)
[M::mem_pestat] mean and std.dev: (610.44, 477.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3697)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 259, 902)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2302)
[M::mem_pestat] mean and std.dev: (405.09, 345.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3002)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 13, #reads = 1074427 mem = 536882351 peak = 840769536
[M::process] read 695006 sequences (100000133 bp) in 3.230 CPU sec, 3.519 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 282402, 33, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (277, 394, 1369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3553)
[M::mem_pestat] mean and std.dev: (855.38, 949.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4655)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 254, 373)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 783)
[M::mem_pestat] mean and std.dev: (282.14, 143.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 988)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 588, 1982)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5606)
[M::mem_pestat] mean and std.dev: (974.94, 1157.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7418)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 207, 546)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1258)
[M::mem_pestat] mean and std.dev: (278.10, 136.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1614)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 694698 reads in 199.454 CPU sec, 6.490 real sec
[M::process] read 701918 sequences (100000191 bp) in 2.529 CPU sec, 2.593 real sec...
[M::mem_process_seqs] Processed 694232 reads in 143.337 CPU sec, 4.685 real sec
sorting block 14, #reads = 1076211 mem = 536877179 peak = 840769536
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 282976, 27, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 1050, 2978)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8486)
[M::mem_pestat] mean and std.dev: (1458.05, 1647.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11240)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 253, 371)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 779)
[M::mem_pestat] mean and std.dev: (280.31, 142.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 983)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (587, 720, 1091)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2099)
[M::mem_pestat] mean and std.dev: (769.77, 408.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2603)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 389, 1073)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2809)
[M::mem_pestat] mean and std.dev: (523.05, 496.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3677)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700700 sequences (100000122 bp) in 3.019 CPU sec, 3.247 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 285345, 20, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 347, 1369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3715)
[M::mem_pestat] mean and std.dev: (689.49, 739.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4888)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 232, 345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 725)
[M::mem_pestat] mean and std.dev: (261.11, 134.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 915)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (517, 706, 8360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 24046)
[M::mem_pestat] mean and std.dev: (2704.40, 3322.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 31889)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 322, 799)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2097)
[M::mem_pestat] mean and std.dev: (343.80, 313.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2746)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695006 reads in 202.068 CPU sec, 6.552 real sec
[M::mem_process_seqs] Processed 701918 reads in 142.590 CPU sec, 4.558 real sec
[M::process] read 700660 sequences (100000057 bp) in 2.796 CPU sec, 2.892 real sec...
sorting block 15, #reads = 1074850 mem = 536877115 peak = 840769536
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 285279, 20, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 331, 1020)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2696)
[M::mem_pestat] mean and std.dev: (703.59, 787.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3853)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 235, 349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 733)
[M::mem_pestat] mean and std.dev: (264.08, 136.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 925)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (502, 641, 2708)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7120)
[M::mem_pestat] mean and std.dev: (1501.10, 1667.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9326)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (257, 414, 1082)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2732)
[M::mem_pestat] mean and std.dev: (656.49, 556.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3557)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699922 sequences (100000159 bp) in 3.425 CPU sec, 3.697 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 285014, 23, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 295, 953)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2449)
[M::mem_pestat] mean and std.dev: (450.83, 404.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3197)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 236, 352)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 742)
[M::mem_pestat] mean and std.dev: (265.91, 137.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 937)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (293, 855, 2004)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5426)
[M::mem_pestat] mean and std.dev: (1175.70, 1274.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7137)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (322, 888, 1731)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4549)
[M::mem_pestat] mean and std.dev: (1026.48, 810.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5958)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700700 reads in 194.179 CPU sec, 6.248 real sec
sorting block 16, #reads = 1079326 mem = 536877114 peak = 840769536
[M::mem_process_seqs] Processed 700660 reads in 138.481 CPU sec, 4.420 real sec
[M::process] read 699790 sequences (100000247 bp) in 2.808 CPU sec, 2.924 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 284414, 19, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 545, 1251)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3355)
[M::mem_pestat] mean and std.dev: (598.27, 477.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4407)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 237, 353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 743)
[M::mem_pestat] mean and std.dev: (266.58, 137.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 938)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (65, 1282, 2058)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6044)
[M::mem_pestat] mean and std.dev: (1330.95, 1418.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8037)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (379, 784, 1064)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2434)
[M::mem_pestat] mean and std.dev: (709.42, 368.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3119)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 17, #reads = 1079853 mem = 536886543 peak = 840769536
[M::process] read 698724 sequences (100000097 bp) in 2.879 CPU sec, 3.043 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (16, 284684, 26, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (234, 408, 669)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1539)
[M::mem_pestat] mean and std.dev: (428.38, 288.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1974)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 239, 355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 747)
[M::mem_pestat] mean and std.dev: (267.90, 138.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 943)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (277, 1039, 1956)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5314)
[M::mem_pestat] mean and std.dev: (1101.42, 785.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6993)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 504, 1614)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4408)
[M::mem_pestat] mean and std.dev: (914.48, 953.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5805)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699922 reads in 194.334 CPU sec, 6.256 real sec
[M::mem_process_seqs] Processed 699790 reads in 136.932 CPU sec, 4.339 real sec
[M::process] read 698102 sequences (100000072 bp) in 2.860 CPU sec, 2.957 real sec...
sorting block 18, #reads = 1080185 mem = 536880210 peak = 840769536
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 284689, 20, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 273, 785)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1941)
[M::mem_pestat] mean and std.dev: (466.48, 433.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2519)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 241, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 760)
[M::mem_pestat] mean and std.dev: (270.86, 139.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 960)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (277, 616, 1104)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2758)
[M::mem_pestat] mean and std.dev: (766.68, 748.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3761)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 431, 641)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1513)
[M::mem_pestat] mean and std.dev: (397.29, 275.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1949)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697572 sequences (100000025 bp) in 3.199 CPU sec, 3.364 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 284057, 21, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (256, 466, 890)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2158)
[M::mem_pestat] mean and std.dev: (518.87, 336.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2792)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 243, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 761)
[M::mem_pestat] mean and std.dev: (272.50, 140.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 961)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (306, 1020, 2070)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5598)
[M::mem_pestat] mean and std.dev: (1404.71, 1502.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7414)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (368, 518, 587)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1025)
[M::mem_pestat] mean and std.dev: (474.38, 188.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1244)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698724 reads in 189.427 CPU sec, 6.043 real sec
[M::process] read 697534 sequences (100000070 bp) in 2.314 CPU sec, 2.373 real sec...
[M::mem_process_seqs] Processed 698102 reads in 135.554 CPU sec, 4.293 real sec
sorting block 19, #reads = 1079188 mem = 536880553 peak = 840769536
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 284370, 22, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 544, 1559)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4361)
[M::mem_pestat] mean and std.dev: (847.22, 835.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5762)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 245, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 771)
[M::mem_pestat] mean and std.dev: (275.03, 142.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 974)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (237, 897, 1345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3561)
[M::mem_pestat] mean and std.dev: (859.57, 801.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4669)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 284, 386)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 734)
[M::mem_pestat] mean and std.dev: (289.72, 125.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 908)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697362 sequences (100000021 bp) in 3.136 CPU sec, 3.360 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 283849, 14, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 650, 1156)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3040)
[M::mem_pestat] mean and std.dev: (767.20, 692.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3982)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 245, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 774)
[M::mem_pestat] mean and std.dev: (275.55, 142.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 978)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (113, 533, 1001)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2777)
[M::mem_pestat] mean and std.dev: (549.50, 709.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3665)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 344, 1360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3684)
[M::mem_pestat] mean and std.dev: (740.28, 917.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4846)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697572 reads in 199.572 CPU sec, 6.390 real sec
sorting block 20, #reads = 1078937 mem = 536878570 peak = 840769536
[M::mem_process_seqs] Processed 697534 reads in 144.168 CPU sec, 4.581 real sec
[M::process] read 697212 sequences (100000256 bp) in 2.963 CPU sec, 3.039 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 283996, 38, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 367, 672)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1630)
[M::mem_pestat] mean and std.dev: (401.69, 262.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2109)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 245, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 774)
[M::mem_pestat] mean and std.dev: (275.84, 143.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 978)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (644, 1163, 7443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 21041)
[M::mem_pestat] mean and std.dev: (2761.89, 2997.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 27840)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (123, 260, 581)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1497)
[M::mem_pestat] mean and std.dev: (323.35, 281.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1955)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 21, #reads = 1078587 mem = 536881647 peak = 840769536
[M::process] read 697518 sequences (100000205 bp) in 3.868 CPU sec, 4.237 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 283715, 24, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 292, 938)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2420)
[M::mem_pestat] mean and std.dev: (484.27, 423.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3161)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 245, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 768)
[M::mem_pestat] mean and std.dev: (275.04, 142.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 970)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 567, 1200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3138)
[M::mem_pestat] mean and std.dev: (740.04, 716.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4107)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (267, 323, 543)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1095)
[M::mem_pestat] mean and std.dev: (341.80, 180.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1371)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697362 reads in 201.197 CPU sec, 6.476 real sec
[M::mem_process_seqs] Processed 697212 reads in 143.745 CPU sec, 4.571 real sec
[M::process] read 697340 sequences (100000012 bp) in 2.898 CPU sec, 3.032 real sec...
sorting block 22, #reads = 1076856 mem = 536880137 peak = 840769536
[M::process] read 697564 sequences (100000166 bp) in 2.894 CPU sec, 3.049 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 283202, 28, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (228, 384, 940)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2364)
[M::mem_pestat] mean and std.dev: (491.03, 428.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3076)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 244, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 765)
[M::mem_pestat] mean and std.dev: (274.53, 142.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 966)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (232, 354, 957)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2407)
[M::mem_pestat] mean and std.dev: (410.17, 403.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3132)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 244, 764)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1876)
[M::mem_pestat] mean and std.dev: (445.09, 378.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2432)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697340 reads in 112.272 CPU sec, 3.545 real sec
[M::process] read 697398 sequences (100000167 bp) in 2.475 CPU sec, 2.523 real sec...
sorting block 23, #reads = 1076409 mem = 536879515 peak = 840769536
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 283814, 29, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 403, 789)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1977)
[M::mem_pestat] mean and std.dev: (453.38, 374.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2571)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 243, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 762)
[M::mem_pestat] mean and std.dev: (273.46, 141.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 962)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (506, 800, 2455)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6353)
[M::mem_pestat] mean and std.dev: (1403.93, 1520.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8302)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 333, 1082)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2870)
[M::mem_pestat] mean and std.dev: (468.40, 390.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3764)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 283534, 15, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 442, 827)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2059)
[M::mem_pestat] mean and std.dev: (528.22, 459.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2675)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 243, 357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 747)
[M::mem_pestat] mean and std.dev: (271.02, 138.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 942)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (110, 346, 1936)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5588)
[M::mem_pestat] mean and std.dev: (613.31, 710.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7414)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 268, 943)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2501)
[M::mem_pestat] mean and std.dev: (490.11, 406.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3280)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697518 reads in 305.639 CPU sec, 9.742 real sec
[M::process] read 697774 sequences (100000301 bp) in 2.679 CPU sec, 2.717 real sec...
[M::mem_process_seqs] Processed 697564 reads in 165.907 CPU sec, 5.254 real sec
sorting block 24, #reads = 1075734 mem = 536879662 peak = 840769536
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 283748, 16, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 338, 1087)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2861)
[M::mem_pestat] mean and std.dev: (570.42, 518.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3748)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 241, 355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 741)
[M::mem_pestat] mean and std.dev: (269.38, 136.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 934)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 527, 1427)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3867)
[M::mem_pestat] mean and std.dev: (905.88, 962.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5087)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (275, 442, 822)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1916)
[M::mem_pestat] mean and std.dev: (532.03, 376.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2463)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696782 sequences (100000209 bp) in 3.220 CPU sec, 3.361 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 283490, 17, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (249, 319, 1500)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4002)
[M::mem_pestat] mean and std.dev: (753.23, 983.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5253)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 241, 357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 749)
[M::mem_pestat] mean and std.dev: (270.49, 138.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 945)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (129, 336, 1141)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3165)
[M::mem_pestat] mean and std.dev: (420.53, 383.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4177)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (361, 556, 1084)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2530)
[M::mem_pestat] mean and std.dev: (678.71, 505.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3253)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696582 sequences (100000175 bp) in 2.089 CPU sec, 2.085 real sec...
[M::mem_process_seqs] Processed 697398 reads in 191.273 CPU sec, 6.066 real sec
sorting block 25, #reads = 1076416 mem = 536877871 peak = 840769536
[M::mem_process_seqs] Processed 697774 reads in 137.716 CPU sec, 4.371 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 284013, 13, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (229, 349, 670)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1552)
[M::mem_pestat] mean and std.dev: (418.00, 312.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1993)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 244, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 751)
[M::mem_pestat] mean and std.dev: (272.18, 138.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 947)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (729, 813, 3841)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10065)
[M::mem_pestat] mean and std.dev: (1862.46, 1739.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13177)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (251, 571, 1434)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3800)
[M::mem_pestat] mean and std.dev: (881.59, 905.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4983)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696794 sequences (100000079 bp) in 3.256 CPU sec, 3.418 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 283587, 13, 21)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (141, 259, 1604)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4530)
[M::mem_pestat] mean and std.dev: (702.40, 753.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5993)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 245, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 752)
[M::mem_pestat] mean and std.dev: (273.00, 138.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 948)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (86, 476, 4051)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 11981)
[M::mem_pestat] mean and std.dev: (1714.08, 1967.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 15946)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 394, 1378)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3718)
[M::mem_pestat] mean and std.dev: (578.95, 637.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4888)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695892 sequences (100000234 bp) in 1.969 CPU sec, 1.969 real sec...
[M::mem_process_seqs] Processed 696782 reads in 190.490 CPU sec, 6.043 real sec
sorting block 26, #reads = 1075567 mem = 536878131 peak = 840769536
[M::mem_process_seqs] Processed 696582 reads in 133.535 CPU sec, 4.247 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 283755, 20, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 295, 375)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 805)
[M::mem_pestat] mean and std.dev: (247.22, 111.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1020)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 245, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 757)
[M::mem_pestat] mean and std.dev: (273.62, 139.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 955)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (234, 457, 1168)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3036)
[M::mem_pestat] mean and std.dev: (740.50, 695.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3970)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 361, 489)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1193)
[M::mem_pestat] mean and std.dev: (320.16, 219.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1545)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 27, #reads = 1075414 mem = 536879434 peak = 842956800
[M::process] read 695788 sequences (100000009 bp) in 3.143 CPU sec, 3.275 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 283764, 17, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (237, 362, 551)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1179)
[M::mem_pestat] mean and std.dev: (427.88, 248.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1493)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 247, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 762)
[M::mem_pestat] mean and std.dev: (275.92, 140.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 961)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (419, 513, 2419)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6419)
[M::mem_pestat] mean and std.dev: (934.13, 794.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8419)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 331, 752)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1866)
[M::mem_pestat] mean and std.dev: (424.84, 284.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2423)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695560 sequences (100000173 bp) in 2.209 CPU sec, 2.212 real sec...
[M::mem_process_seqs] Processed 696794 reads in 189.024 CPU sec, 5.994 real sec
[M::mem_process_seqs] Processed 695892 reads in 134.128 CPU sec, 4.278 real sec
sorting block 28, #reads = 1076089 mem = 536879295 peak = 842956800
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 282598, 35, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 471, 1453)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3933)
[M::mem_pestat] mean and std.dev: (974.00, 1083.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5308)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 248, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 765)
[M::mem_pestat] mean and std.dev: (276.62, 141.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 965)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (365, 641, 1102)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2576)
[M::mem_pestat] mean and std.dev: (651.62, 474.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3313)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (247, 382, 1007)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2527)
[M::mem_pestat] mean and std.dev: (569.52, 475.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3287)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695766 sequences (100000117 bp) in 3.511 CPU sec, 3.679 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 282785, 14, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (261, 370, 989)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2445)
[M::mem_pestat] mean and std.dev: (442.19, 349.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3173)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 248, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 771)
[M::mem_pestat] mean and std.dev: (277.21, 141.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 973)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 353, 872)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2216)
[M::mem_pestat] mean and std.dev: (414.08, 322.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2888)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (238, 282, 1032)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2620)
[M::mem_pestat] mean and std.dev: (501.00, 464.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3414)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695788 reads in 193.309 CPU sec, 6.126 real sec
[M::process] read 695602 sequences (100000151 bp) in 2.474 CPU sec, 2.490 real sec...
[M::mem_process_seqs] Processed 695560 reads in 135.981 CPU sec, 4.306 real sec
sorting block 29, #reads = 1075019 mem = 536877591 peak = 842956800
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 283126, 18, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 508, 1187)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3187)
[M::mem_pestat] mean and std.dev: (738.44, 754.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4187)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 249, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 768)
[M::mem_pestat] mean and std.dev: (277.13, 141.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 969)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (476, 1874, 2931)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7841)
[M::mem_pestat] mean and std.dev: (2375.67, 2284.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11512)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (243, 335, 397)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 705)
[M::mem_pestat] mean and std.dev: (292.75, 97.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 859)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696710 sequences (100000014 bp) in 3.341 CPU sec, 3.520 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 283283, 17, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 277, 1295)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3551)
[M::mem_pestat] mean and std.dev: (631.81, 673.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4679)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 249, 368)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 774)
[M::mem_pestat] mean and std.dev: (278.15, 142.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 977)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (141, 634, 1697)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4809)
[M::mem_pestat] mean and std.dev: (679.44, 592.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6365)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 400, 911)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2305)
[M::mem_pestat] mean and std.dev: (557.84, 427.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3002)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695766 reads in 192.966 CPU sec, 6.129 real sec
[M::process] read 702958 sequences (100000068 bp) in 2.350 CPU sec, 2.363 real sec...
[M::mem_process_seqs] Processed 695602 reads in 135.072 CPU sec, 4.278 real sec
sorting block 30, #reads = 1074726 mem = 536886501 peak = 842956800
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 283222, 27, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 284, 993)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2663)
[M::mem_pestat] mean and std.dev: (481.79, 472.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3498)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 247, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 772)
[M::mem_pestat] mean and std.dev: (276.24, 142.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 975)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (542, 967, 1800)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4316)
[M::mem_pestat] mean and std.dev: (1113.12, 854.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5574)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (266, 418, 1705)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4583)
[M::mem_pestat] mean and std.dev: (617.69, 733.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6022)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702298 sequences (100000244 bp) in 3.011 CPU sec, 3.190 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 285528, 25, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 314, 799)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2065)
[M::mem_pestat] mean and std.dev: (521.34, 517.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2698)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 228, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 714)
[M::mem_pestat] mean and std.dev: (257.05, 132.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 901)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (558, 1085, 1630)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3774)
[M::mem_pestat] mean and std.dev: (1255.72, 946.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5043)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (274, 390, 592)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1228)
[M::mem_pestat] mean and std.dev: (380.07, 169.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1546)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702372 sequences (100000111 bp) in 2.207 CPU sec, 2.206 real sec...
[M::mem_process_seqs] Processed 696710 reads in 197.837 CPU sec, 6.289 real sec
sorting block 31, #reads = 1075399 mem = 536879805 peak = 842956800
[M::mem_process_seqs] Processed 702958 reads in 138.416 CPU sec, 4.399 real sec
sorting block 32, #reads = 1077356 mem = 536877710 peak = 846774272
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 285271, 19, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 426, 890)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2304)
[M::mem_pestat] mean and std.dev: (514.61, 354.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3011)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 230, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 722)
[M::mem_pestat] mean and std.dev: (260.22, 134.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 911)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (397, 602, 2176)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5734)
[M::mem_pestat] mean and std.dev: (1061.79, 956.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7513)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 255, 1000)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2554)
[M::mem_pestat] mean and std.dev: (474.30, 378.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3331)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700750 sequences (100000043 bp) in 3.021 CPU sec, 3.142 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 285252, 33, 19)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 309, 1391)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3817)
[M::mem_pestat] mean and std.dev: (640.52, 596.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5030)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 231, 345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 727)
[M::mem_pestat] mean and std.dev: (260.31, 133.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 918)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (352, 772, 1440)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3616)
[M::mem_pestat] mean and std.dev: (962.85, 634.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4704)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 554, 1595)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4403)
[M::mem_pestat] mean and std.dev: (972.95, 958.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5807)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702298 reads in 194.565 CPU sec, 6.195 real sec
[M::process] read 700230 sequences (100000222 bp) in 2.545 CPU sec, 2.577 real sec...
[M::mem_process_seqs] Processed 702372 reads in 138.711 CPU sec, 4.399 real sec
sorting block 33, #reads = 1079758 mem = 536881767 peak = 846774272
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 284759, 28, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 438, 901)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2255)
[M::mem_pestat] mean and std.dev: (576.21, 475.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2932)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 234, 347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 727)
[M::mem_pestat] mean and std.dev: (262.62, 133.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 917)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (346, 521, 1909)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5035)
[M::mem_pestat] mean and std.dev: (932.28, 948.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6598)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 325, 594)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1424)
[M::mem_pestat] mean and std.dev: (330.71, 236.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1839)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699106 sequences (100000286 bp) in 2.927 CPU sec, 3.070 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 284664, 15, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (294, 450, 690)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1482)
[M::mem_pestat] mean and std.dev: (488.11, 306.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1878)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 237, 350)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 734)
[M::mem_pestat] mean and std.dev: (264.82, 135.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 926)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (336, 579, 1143)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2757)
[M::mem_pestat] mean and std.dev: (762.87, 651.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3564)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (241, 508, 956)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2386)
[M::mem_pestat] mean and std.dev: (552.21, 407.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3101)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698622 sequences (100000174 bp) in 2.220 CPU sec, 2.227 real sec...
[M::mem_process_seqs] Processed 700750 reads in 195.342 CPU sec, 6.217 real sec
[M::mem_process_seqs] Processed 700230 reads in 136.767 CPU sec, 4.347 real sec
sorting block 34, #reads = 1079050 mem = 536878426 peak = 846774272
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 284079, 39, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (123, 206, 654)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1716)
[M::mem_pestat] mean and std.dev: (376.25, 362.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2247)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 239, 354)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 744)
[M::mem_pestat] mean and std.dev: (267.59, 136.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 939)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (540, 1002, 1707)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4041)
[M::mem_pestat] mean and std.dev: (1115.82, 835.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5208)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (261, 414, 727)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1659)
[M::mem_pestat] mean and std.dev: (479.34, 313.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2125)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698232 sequences (100000286 bp) in 3.577 CPU sec, 3.882 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 283712, 20, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 246, 624)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1532)
[M::mem_pestat] mean and std.dev: (314.63, 262.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1986)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 241, 356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 748)
[M::mem_pestat] mean and std.dev: (269.39, 137.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 944)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (383, 954, 1847)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4775)
[M::mem_pestat] mean and std.dev: (1032.25, 810.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6239)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 327, 707)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1701)
[M::mem_pestat] mean and std.dev: (455.10, 332.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2198)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699106 reads in 195.768 CPU sec, 6.238 real sec
sorting block 35, #reads = 1078577 mem = 536879284 peak = 858353664
[M::mem_process_seqs] Processed 698622 reads in 136.309 CPU sec, 4.322 real sec
[M::process] read 697604 sequences (100000237 bp) in 2.385 CPU sec, 2.449 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 284641, 17, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 327, 655)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1577)
[M::mem_pestat] mean and std.dev: (467.16, 415.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2131)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 243, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 752)
[M::mem_pestat] mean and std.dev: (270.63, 137.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 949)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (46, 384, 925)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2683)
[M::mem_pestat] mean and std.dev: (517.71, 633.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3562)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 222, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 802)
[M::mem_pestat] mean and std.dev: (238.27, 133.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1020)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 36, #reads = 1077541 mem = 536877027 peak = 867753984
[M::process] read 697980 sequences (100000076 bp) in 3.061 CPU sec, 3.237 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 284166, 24, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 294, 1025)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2695)
[M::mem_pestat] mean and std.dev: (523.59, 481.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3530)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 245, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 762)
[M::mem_pestat] mean and std.dev: (273.18, 139.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 962)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (315, 800, 1690)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4440)
[M::mem_pestat] mean and std.dev: (1036.78, 996.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5815)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (246, 423, 1201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3111)
[M::mem_pestat] mean and std.dev: (675.88, 520.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4066)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698232 reads in 197.768 CPU sec, 6.308 real sec
[M::process] read 697410 sequences (100000255 bp) in 2.192 CPU sec, 2.213 real sec...
[M::mem_process_seqs] Processed 697604 reads in 137.930 CPU sec, 4.381 real sec
sorting block 37, #reads = 1078065 mem = 536878347 peak = 867753984
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 283919, 11, 21)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 426, 1731)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4837)
[M::mem_pestat] mean and std.dev: (981.12, 1195.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6390)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 244, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 753)
[M::mem_pestat] mean and std.dev: (271.55, 138.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 950)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (80, 656, 1917)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5591)
[M::mem_pestat] mean and std.dev: (913.90, 966.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7428)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (261, 272, 774)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1800)
[M::mem_pestat] mean and std.dev: (394.16, 296.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2313)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697374 sequences (100000076 bp) in 3.773 CPU sec, 4.048 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 283679, 24, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 298, 1233)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3265)
[M::mem_pestat] mean and std.dev: (611.17, 780.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4281)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 244, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 759)
[M::mem_pestat] mean and std.dev: (273.17, 139.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 958)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 563, 620)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1498)
[M::mem_pestat] mean and std.dev: (445.50, 310.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1937)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (231, 378, 962)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2424)
[M::mem_pestat] mean and std.dev: (521.13, 468.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3155)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697980 reads in 200.894 CPU sec, 6.394 real sec
[M::mem_process_seqs] Processed 697410 reads in 143.099 CPU sec, 4.537 real sec
[M::process] read 698162 sequences (100000144 bp) in 2.730 CPU sec, 2.817 real sec...
sorting block 38, #reads = 1077630 mem = 536880324 peak = 867753984
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 283473, 25, 21)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (297, 789, 974)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2328)
[M::mem_pestat] mean and std.dev: (664.26, 433.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3005)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 246, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 765)
[M::mem_pestat] mean and std.dev: (274.07, 140.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 966)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (103, 668, 1402)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4000)
[M::mem_pestat] mean and std.dev: (543.35, 492.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5299)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 172, 533)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1301)
[M::mem_pestat] mean and std.dev: (278.53, 196.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1685)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697096 sequences (100000295 bp) in 3.146 CPU sec, 3.346 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 283578, 23, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 325, 1071)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2813)
[M::mem_pestat] mean and std.dev: (621.31, 692.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3684)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 241, 356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 746)
[M::mem_pestat] mean and std.dev: (269.42, 137.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 941)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (660, 911, 1658)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3654)
[M::mem_pestat] mean and std.dev: (1142.00, 829.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4652)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (249, 427, 708)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1626)
[M::mem_pestat] mean and std.dev: (374.63, 205.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2085)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697374 reads in 204.334 CPU sec, 6.543 real sec
sorting block 39, #reads = 1076682 mem = 536877879 peak = 867753984
[M::process] read 696974 sequences (100000171 bp) in 2.504 CPU sec, 2.591 real sec...
[M::mem_process_seqs] Processed 698162 reads in 144.897 CPU sec, 4.592 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 283349, 19, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 386, 1219)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3291)
[M::mem_pestat] mean and std.dev: (646.12, 625.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4327)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 244, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 751)
[M::mem_pestat] mean and std.dev: (272.19, 138.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 947)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 468, 1350)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3728)
[M::mem_pestat] mean and std.dev: (675.29, 801.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4917)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 338, 1618)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4462)
[M::mem_pestat] mean and std.dev: (908.59, 1025.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5884)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 40, #reads = 1077768 mem = 536877999 peak = 975372288
[M::process] read 697110 sequences (100000141 bp) in 3.192 CPU sec, 3.358 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (22, 283274, 22, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 542, 1035)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2697)
[M::mem_pestat] mean and std.dev: (484.00, 346.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3528)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 244, 357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 745)
[M::mem_pestat] mean and std.dev: (270.95, 137.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 939)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (140, 460, 1095)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3005)
[M::mem_pestat] mean and std.dev: (561.05, 574.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3960)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (262, 322, 1109)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2803)
[M::mem_pestat] mean and std.dev: (511.50, 429.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3650)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697096 reads in 201.715 CPU sec, 6.452 real sec
[M::process] read 696752 sequences (100000283 bp) in 2.424 CPU sec, 2.483 real sec...
[M::mem_process_seqs] Processed 696974 reads in 143.630 CPU sec, 4.562 real sec
sorting block 41, #reads = 1075706 mem = 536885058 peak = 975372288
[M::process] read 696276 sequences (100000294 bp) in 3.245 CPU sec, 3.452 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 282725, 27, 20)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (247, 425, 1286)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3364)
[M::mem_pestat] mean and std.dev: (581.98, 583.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4403)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 245, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 754)
[M::mem_pestat] mean and std.dev: (272.94, 138.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 951)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (258, 764, 2543)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7113)
[M::mem_pestat] mean and std.dev: (1169.41, 1141.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9398)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 335, 652)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1520)
[M::mem_pestat] mean and std.dev: (432.11, 339.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1954)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696752 reads in 119.090 CPU sec, 3.757 real sec
[M::process] read 696220 sequences (100000042 bp) in 2.567 CPU sec, 2.645 real sec...
sorting block 42, #reads = 1074879 mem = 536880134 peak = 975372288
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 283216, 29, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 392, 533)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1197)
[M::mem_pestat] mean and std.dev: (343.20, 183.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1529)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 243, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 750)
[M::mem_pestat] mean and std.dev: (271.20, 137.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 946)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (234, 427, 2260)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6312)
[M::mem_pestat] mean and std.dev: (931.71, 1096.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8338)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (316, 453, 1209)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2995)
[M::mem_pestat] mean and std.dev: (573.56, 465.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3888)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 283221, 15, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (280, 602, 2162)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5926)
[M::mem_pestat] mean and std.dev: (1238.97, 1442.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7808)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 245, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 754)
[M::mem_pestat] mean and std.dev: (273.05, 138.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 951)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (128, 354, 1142)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3170)
[M::mem_pestat] mean and std.dev: (521.43, 538.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4184)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 438, 664)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1614)
[M::mem_pestat] mean and std.dev: (428.65, 307.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2089)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697110 reads in 323.424 CPU sec, 10.324 real sec
[M::mem_process_seqs] Processed 696276 reads in 174.880 CPU sec, 5.574 real sec
[M::process] read 696100 sequences (100000001 bp) in 2.888 CPU sec, 2.979 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 283349, 30, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (334, 410, 906)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2050)
[M::mem_pestat] mean and std.dev: (566.47, 443.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2622)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 246, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 749)
[M::mem_pestat] mean and std.dev: (272.65, 137.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 944)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (257, 573, 1715)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4631)
[M::mem_pestat] mean and std.dev: (737.35, 825.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6089)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 478, 950)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2446)
[M::mem_pestat] mean and std.dev: (632.00, 568.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3194)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 43, #reads = 1075080 mem = 536878373 peak = 975372288
[M::process] read 696778 sequences (100000116 bp) in 3.436 CPU sec, 3.654 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 282989, 25, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (261, 482, 847)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2019)
[M::mem_pestat] mean and std.dev: (454.49, 240.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2605)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 246, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 758)
[M::mem_pestat] mean and std.dev: (274.25, 139.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 956)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (385, 483, 3026)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8308)
[M::mem_pestat] mean and std.dev: (1674.24, 1767.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10949)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (279, 349, 612)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1278)
[M::mem_pestat] mean and std.dev: (400.44, 191.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1611)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696220 reads in 206.429 CPU sec, 6.617 real sec
[M::mem_process_seqs] Processed 696100 reads in 146.430 CPU sec, 4.644 real sec
[M::process] read 695870 sequences (100000203 bp) in 2.859 CPU sec, 2.995 real sec...
sorting block 44, #reads = 1075082 mem = 536878881 peak = 975372288
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 283096, 20, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 546, 1232)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3296)
[M::mem_pestat] mean and std.dev: (679.03, 571.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4328)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 246, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 760)
[M::mem_pestat] mean and std.dev: (274.49, 140.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 959)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (316, 678, 1116)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2716)
[M::mem_pestat] mean and std.dev: (719.00, 535.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3516)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (143, 241, 619)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1571)
[M::mem_pestat] mean and std.dev: (238.57, 167.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2047)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696106 sequences (100000265 bp) in 3.155 CPU sec, 3.317 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 283205, 11, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 427, 1278)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3506)
[M::mem_pestat] mean and std.dev: (806.63, 897.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4620)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 247, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 768)
[M::mem_pestat] mean and std.dev: (276.70, 142.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 969)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1037, 2355, 2355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4991)
[M::mem_pestat] mean and std.dev: (1698.45, 1022.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6309)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 299, 435)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 915)
[M::mem_pestat] mean and std.dev: (289.79, 122.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1155)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696778 reads in 212.117 CPU sec, 6.781 real sec
[M::process] read 696170 sequences (100000016 bp) in 2.322 CPU sec, 2.354 real sec...
[M::mem_process_seqs] Processed 695870 reads in 148.981 CPU sec, 4.743 real sec
sorting block 45, #reads = 1074368 mem = 536877867 peak = 975372288
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 283653, 13, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (298, 413, 777)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1735)
[M::mem_pestat] mean and std.dev: (458.67, 266.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2214)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 245, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 764)
[M::mem_pestat] mean and std.dev: (275.13, 141.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 964)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (451, 636, 967)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1999)
[M::mem_pestat] mean and std.dev: (650.92, 414.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2515)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 294, 976)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2482)
[M::mem_pestat] mean and std.dev: (416.58, 318.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3235)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 46, #reads = 1073996 mem = 536883727 peak = 975372288
[M::process] read 699212 sequences (100000300 bp) in 3.440 CPU sec, 3.649 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 283311, 23, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 458, 877)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2183)
[M::mem_pestat] mean and std.dev: (573.94, 540.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2836)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 246, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 761)
[M::mem_pestat] mean and std.dev: (274.78, 140.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 960)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (140, 612, 1813)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5159)
[M::mem_pestat] mean and std.dev: (1030.86, 1303.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6832)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 403, 649)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1543)
[M::mem_pestat] mean and std.dev: (443.57, 316.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1990)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696106 reads in 202.855 CPU sec, 6.469 real sec
[M::process] read 701254 sequences (100000168 bp) in 2.284 CPU sec, 2.321 real sec...
[M::mem_process_seqs] Processed 696170 reads in 143.130 CPU sec, 4.543 real sec
sorting block 47, #reads = 1073929 mem = 536879788 peak = 975372288
[M::process] read 701032 sequences (100000052 bp) in 3.065 CPU sec, 3.242 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 285037, 21, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (244, 452, 1023)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2581)
[M::mem_pestat] mean and std.dev: (643.79, 523.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3360)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 233, 346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 726)
[M::mem_pestat] mean and std.dev: (261.53, 134.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 916)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (336, 1592, 2856)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7896)
[M::mem_pestat] mean and std.dev: (1331.62, 1055.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10416)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 262, 1248)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3358)
[M::mem_pestat] mean and std.dev: (514.55, 618.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4413)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701254 reads in 111.058 CPU sec, 3.505 real sec
[M::process] read 700652 sequences (100000014 bp) in 2.206 CPU sec, 2.217 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 283954, 27, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (342, 807, 1142)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2742)
[M::mem_pestat] mean and std.dev: (712.66, 511.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3542)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 239, 352)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 738)
[M::mem_pestat] mean and std.dev: (266.94, 136.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 931)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 628, 1425)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3917)
[M::mem_pestat] mean and std.dev: (758.08, 644.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5163)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 326, 1054)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2722)
[M::mem_pestat] mean and std.dev: (567.03, 638.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3556)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 285238, 31, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 414, 1418)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3820)
[M::mem_pestat] mean and std.dev: (657.27, 687.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5021)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 234, 348)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 732)
[M::mem_pestat] mean and std.dev: (262.96, 134.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 924)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 629, 1280)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3422)
[M::mem_pestat] mean and std.dev: (610.15, 544.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4493)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (274, 644, 1535)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4057)
[M::mem_pestat] mean and std.dev: (839.75, 686.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5318)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699212 reads in 315.074 CPU sec, 10.050 real sec
sorting block 48, #reads = 1078813 mem = 536879689 peak = 975372288
[M::process] read 700406 sequences (100000086 bp) in 2.685 CPU sec, 2.720 real sec...
[M::mem_process_seqs] Processed 701032 reads in 169.719 CPU sec, 5.418 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 285245, 29, 24)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 378, 844)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2176)
[M::mem_pestat] mean and std.dev: (494.31, 411.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2842)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 235, 349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 733)
[M::mem_pestat] mean and std.dev: (264.30, 135.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 925)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (330, 826, 1570)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4050)
[M::mem_pestat] mean and std.dev: (828.57, 703.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5290)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 265, 1261)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3405)
[M::mem_pestat] mean and std.dev: (558.73, 663.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4477)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 49, #reads = 1075929 mem = 536881090 peak = 975372288
[M::process] read 700036 sequences (100000016 bp) in 3.841 CPU sec, 4.140 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 284590, 12, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 358, 661)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1647)
[M::mem_pestat] mean and std.dev: (342.24, 249.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2140)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 236, 352)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 740)
[M::mem_pestat] mean and std.dev: (265.66, 136.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 934)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (113, 442, 1604)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4586)
[M::mem_pestat] mean and std.dev: (799.83, 805.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6077)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (289, 396, 1069)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2629)
[M::mem_pestat] mean and std.dev: (601.19, 623.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3409)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700652 reads in 200.165 CPU sec, 6.446 real sec
[M::mem_process_seqs] Processed 700406 reads in 144.353 CPU sec, 4.605 real sec
[M::process] read 699352 sequences (100000266 bp) in 2.837 CPU sec, 3.009 real sec...
sorting block 50, #reads = 1080899 mem = 536881197 peak = 975372288
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 284551, 29, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 397, 671)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1631)
[M::mem_pestat] mean and std.dev: (428.14, 335.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2111)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 237, 352)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 738)
[M::mem_pestat] mean and std.dev: (266.08, 136.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 931)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (120, 473, 2001)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5763)
[M::mem_pestat] mean and std.dev: (1064.45, 1117.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7644)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (262, 431, 966)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2374)
[M::mem_pestat] mean and std.dev: (678.13, 595.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3078)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698524 sequences (100000285 bp) in 3.662 CPU sec, 3.928 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 284489, 13, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (296, 523, 537)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1019)
[M::mem_pestat] mean and std.dev: (402.77, 172.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1260)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 239, 355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 747)
[M::mem_pestat] mean and std.dev: (268.06, 137.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 943)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (107, 195, 823)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2255)
[M::mem_pestat] mean and std.dev: (295.67, 299.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2971)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 489, 807)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2007)
[M::mem_pestat] mean and std.dev: (407.65, 265.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2607)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700036 reads in 200.941 CPU sec, 6.467 real sec
[M::mem_process_seqs] Processed 699352 reads in 141.791 CPU sec, 4.527 real sec
sorting block 51, #reads = 1079057 mem = 536881611 peak = 975372288
[M::process] read 698208 sequences (100000083 bp) in 3.152 CPU sec, 3.351 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 284447, 28, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 270, 1082)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2942)
[M::mem_pestat] mean and std.dev: (483.88, 544.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3872)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 241, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 754)
[M::mem_pestat] mean and std.dev: (270.42, 138.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 952)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (396, 871, 2542)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6834)
[M::mem_pestat] mean and std.dev: (1393.43, 1374.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8980)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (235, 368, 751)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1783)
[M::mem_pestat] mean and std.dev: (412.06, 299.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2299)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698078 sequences (100000123 bp) in 3.318 CPU sec, 3.537 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 283518, 22, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 439, 575)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1405)
[M::mem_pestat] mean and std.dev: (405.78, 297.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1820)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 243, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 758)
[M::mem_pestat] mean and std.dev: (271.55, 139.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 957)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (336, 901, 2498)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6822)
[M::mem_pestat] mean and std.dev: (1554.41, 1665.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8984)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (238, 288, 683)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1573)
[M::mem_pestat] mean and std.dev: (420.75, 268.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2018)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698524 reads in 201.171 CPU sec, 6.447 real sec
sorting block 52, #reads = 1079022 mem = 536881725 peak = 975372288
[M::mem_process_seqs] Processed 698208 reads in 143.979 CPU sec, 4.577 real sec
[M::process] read 697940 sequences (100000240 bp) in 2.822 CPU sec, 2.998 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 284171, 21, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 377, 1704)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4708)
[M::mem_pestat] mean and std.dev: (627.59, 620.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6210)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 243, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 759)
[M::mem_pestat] mean and std.dev: (272.46, 139.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 958)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 1032, 2588)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7426)
[M::mem_pestat] mean and std.dev: (1576.81, 1874.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9845)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 337, 641)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1473)
[M::mem_pestat] mean and std.dev: (391.72, 321.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1889)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 53, #reads = 1077742 mem = 536879882 peak = 975372288
[M::process] read 697932 sequences (100000120 bp) in 3.373 CPU sec, 3.527 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 283511, 22, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (247, 301, 1243)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3235)
[M::mem_pestat] mean and std.dev: (680.80, 702.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4231)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 245, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 759)
[M::mem_pestat] mean and std.dev: (272.79, 139.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 958)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (265, 915, 1390)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3640)
[M::mem_pestat] mean and std.dev: (904.00, 801.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4765)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 296, 1082)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2836)
[M::mem_pestat] mean and std.dev: (580.24, 518.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3713)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698078 reads in 197.274 CPU sec, 6.328 real sec
[M::mem_process_seqs] Processed 697940 reads in 140.026 CPU sec, 4.441 real sec
[M::process] read 698082 sequences (100000160 bp) in 2.883 CPU sec, 2.983 real sec...
sorting block 54, #reads = 1078393 mem = 536881794 peak = 975372288
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23, 284344, 20, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 600, 2592)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7374)
[M::mem_pestat] mean and std.dev: (1598.87, 2275.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10700)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 244, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 759)
[M::mem_pestat] mean and std.dev: (272.71, 139.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 958)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (84, 380, 1122)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3198)
[M::mem_pestat] mean and std.dev: (534.10, 493.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4236)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (338, 478, 1214)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2966)
[M::mem_pestat] mean and std.dev: (684.49, 575.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3842)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699858 sequences (100000157 bp) in 3.102 CPU sec, 3.272 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 283922, 23, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 338, 414)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 920)
[M::mem_pestat] mean and std.dev: (280.56, 140.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1173)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 242, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 755)
[M::mem_pestat] mean and std.dev: (271.49, 139.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 953)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (91, 309, 1188)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3382)
[M::mem_pestat] mean and std.dev: (653.70, 744.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4479)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 457, 908)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2364)
[M::mem_pestat] mean and std.dev: (549.43, 430.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3092)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697932 reads in 195.094 CPU sec, 6.243 real sec
[M::process] read 697946 sequences (100000253 bp) in 2.031 CPU sec, 2.038 real sec...
[M::mem_process_seqs] Processed 698082 reads in 142.984 CPU sec, 4.595 real sec
sorting block 55, #reads = 1077335 mem = 536880263 peak = 975372288
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 284326, 21, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 509, 1460)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4040)
[M::mem_pestat] mean and std.dev: (854.15, 694.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5330)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 233, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 716)
[M::mem_pestat] mean and std.dev: (262.36, 134.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 902)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (134, 1081, 2729)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7919)
[M::mem_pestat] mean and std.dev: (1551.65, 1543.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10514)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 361, 641)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1485)
[M::mem_pestat] mean and std.dev: (375.26, 244.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1907)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698282 sequences (100000071 bp) in 3.146 CPU sec, 3.333 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 283839, 27, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (229, 271, 665)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1537)
[M::mem_pestat] mean and std.dev: (374.48, 290.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1973)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 241, 354)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 740)
[M::mem_pestat] mean and std.dev: (268.42, 136.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 933)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (330, 725, 1443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3669)
[M::mem_pestat] mean and std.dev: (937.44, 843.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4782)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (238, 363, 774)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1846)
[M::mem_pestat] mean and std.dev: (465.67, 298.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2382)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697250 sequences (100000220 bp) in 2.240 CPU sec, 2.243 real sec...
[M::mem_process_seqs] Processed 699858 reads in 199.492 CPU sec, 6.360 real sec
sorting block 56, #reads = 1076949 mem = 536881232 peak = 975372288
[M::mem_process_seqs] Processed 697946 reads in 146.163 CPU sec, 4.674 real sec
sorting block 57, #reads = 1076934 mem = 536886683 peak = 975372288
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 283684, 20, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (234, 373, 1668)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4536)
[M::mem_pestat] mean and std.dev: (834.87, 994.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5970)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 239, 352)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 734)
[M::mem_pestat] mean and std.dev: (267.01, 135.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 925)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (243, 736, 6276)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 18342)
[M::mem_pestat] mean and std.dev: (2221.25, 2744.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 24375)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 354, 1197)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3161)
[M::mem_pestat] mean and std.dev: (759.89, 764.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4143)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696982 sequences (100000146 bp) in 2.859 CPU sec, 2.980 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 283429, 30, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (262, 490, 838)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1990)
[M::mem_pestat] mean and std.dev: (558.49, 415.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2566)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 241, 353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 735)
[M::mem_pestat] mean and std.dev: (268.42, 134.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 926)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (327, 652, 1328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3330)
[M::mem_pestat] mean and std.dev: (877.32, 798.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4331)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 295, 854)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2188)
[M::mem_pestat] mean and std.dev: (532.25, 533.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2855)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697392 sequences (100000086 bp) in 2.340 CPU sec, 2.333 real sec...
[M::mem_process_seqs] Processed 698282 reads in 197.679 CPU sec, 6.290 real sec
[M::mem_process_seqs] Processed 697250 reads in 138.757 CPU sec, 4.426 real sec
sorting block 58, #reads = 1074649 mem = 536879720 peak = 975372288
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (19, 283476, 21, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (145, 147, 442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1036)
[M::mem_pestat] mean and std.dev: (173.56, 112.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1333)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 242, 353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 735)
[M::mem_pestat] mean and std.dev: (268.63, 134.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 926)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 506, 1991)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5587)
[M::mem_pestat] mean and std.dev: (874.63, 1074.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7385)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (279, 555, 934)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2244)
[M::mem_pestat] mean and std.dev: (603.17, 466.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2899)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696880 sequences (100000065 bp) in 3.265 CPU sec, 3.416 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 283388, 22, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 500, 1712)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4706)
[M::mem_pestat] mean and std.dev: (794.47, 838.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6203)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 242, 353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 735)
[M::mem_pestat] mean and std.dev: (268.64, 134.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 926)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (247, 505, 1369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3613)
[M::mem_pestat] mean and std.dev: (795.90, 867.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4735)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (298, 472, 1575)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4129)
[M::mem_pestat] mean and std.dev: (869.92, 837.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5406)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696430 sequences (100000263 bp) in 2.090 CPU sec, 2.089 real sec...
[M::mem_process_seqs] Processed 696982 reads in 194.950 CPU sec, 6.201 real sec
[M::mem_process_seqs] Processed 697392 reads in 137.431 CPU sec, 4.374 real sec
sorting block 59, #reads = 1075156 mem = 536881767 peak = 975372288
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 283176, 26, 22)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 401, 707)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1795)
[M::mem_pestat] mean and std.dev: (404.03, 285.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2339)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 243, 353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 733)
[M::mem_pestat] mean and std.dev: (268.40, 133.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 923)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (240, 648, 2313)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6459)
[M::mem_pestat] mean and std.dev: (1091.04, 1121.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8532)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 301, 1084)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2872)
[M::mem_pestat] mean and std.dev: (434.42, 434.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3766)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696222 sequences (100000091 bp) in 3.168 CPU sec, 3.320 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 282958, 16, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (266, 385, 900)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2168)
[M::mem_pestat] mean and std.dev: (549.74, 501.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2802)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 243, 352)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 728)
[M::mem_pestat] mean and std.dev: (268.49, 133.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 916)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (339, 471, 3731)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10515)
[M::mem_pestat] mean and std.dev: (1964.94, 2803.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13907)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 382, 979)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2535)
[M::mem_pestat] mean and std.dev: (496.27, 488.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3313)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696174 sequences (100000268 bp) in 2.146 CPU sec, 2.146 real sec...
[M::mem_process_seqs] Processed 696880 reads in 193.664 CPU sec, 6.151 real sec
sorting block 60, #reads = 1075104 mem = 536879787 peak = 975372288
[M::mem_process_seqs] Processed 696430 reads in 135.667 CPU sec, 4.327 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 283590, 26, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 424, 1180)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3100)
[M::mem_pestat] mean and std.dev: (702.61, 666.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4060)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 245, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 751)
[M::mem_pestat] mean and std.dev: (272.51, 137.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 947)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (82, 353, 1610)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4666)
[M::mem_pestat] mean and std.dev: (688.78, 889.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6194)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (287, 369, 548)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1070)
[M::mem_pestat] mean and std.dev: (391.38, 175.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1331)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 61, #reads = 1074563 mem = 536878260 peak = 1009860608
[M::process] read 696384 sequences (100000150 bp) in 3.086 CPU sec, 3.243 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 283218, 19, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 335, 481)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1115)
[M::mem_pestat] mean and std.dev: (289.73, 161.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1432)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 245, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 752)
[M::mem_pestat] mean and std.dev: (272.91, 138.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 948)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (229, 243, 467)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 943)
[M::mem_pestat] mean and std.dev: (246.00, 134.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1181)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 291, 370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 692)
[M::mem_pestat] mean and std.dev: (261.19, 75.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 853)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695788 sequences (100000295 bp) in 2.390 CPU sec, 2.397 real sec...
[M::mem_process_seqs] Processed 696222 reads in 192.583 CPU sec, 6.120 real sec
[M::mem_process_seqs] Processed 696174 reads in 135.685 CPU sec, 4.305 real sec
sorting block 62, #reads = 1074194 mem = 536879656 peak = 1009860608
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 283039, 22, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 554, 1146)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3018)
[M::mem_pestat] mean and std.dev: (632.53, 565.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3954)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 245, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 754)
[M::mem_pestat] mean and std.dev: (273.11, 138.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 951)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (348, 588, 1137)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2715)
[M::mem_pestat] mean and std.dev: (741.62, 627.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3504)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (280, 501, 1443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3769)
[M::mem_pestat] mean and std.dev: (935.00, 976.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4932)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701936 sequences (100000131 bp) in 3.099 CPU sec, 3.208 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 283957, 21, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (350, 888, 1351)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3353)
[M::mem_pestat] mean and std.dev: (903.23, 759.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4354)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 247, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 764)
[M::mem_pestat] mean and std.dev: (275.46, 140.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 964)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (234, 545, 708)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1656)
[M::mem_pestat] mean and std.dev: (479.05, 357.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2130)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 584, 1113)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2889)
[M::mem_pestat] mean and std.dev: (583.16, 478.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3777)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705036 sequences (100000140 bp) in 2.167 CPU sec, 2.175 real sec...
[M::mem_process_seqs] Processed 696384 reads in 191.043 CPU sec, 6.078 real sec
[M::mem_process_seqs] Processed 695788 reads in 134.546 CPU sec, 4.313 real sec
sorting block 63, #reads = 1073988 mem = 536880425 peak = 1009860608
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 285745, 18, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 403, 551)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1265)
[M::mem_pestat] mean and std.dev: (356.29, 228.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1622)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 228, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 710)
[M::mem_pestat] mean and std.dev: (258.24, 133.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 895)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 327, 1376)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3714)
[M::mem_pestat] mean and std.dev: (782.33, 753.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4883)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (250, 429, 1302)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3406)
[M::mem_pestat] mean and std.dev: (708.41, 614.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4458)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703102 sequences (100000216 bp) in 3.178 CPU sec, 3.314 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 286757, 20, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 305, 441)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 949)
[M::mem_pestat] mean and std.dev: (331.68, 193.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1203)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 218, 323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 669)
[M::mem_pestat] mean and std.dev: (247.57, 127.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 842)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (250, 661, 1910)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5230)
[M::mem_pestat] mean and std.dev: (913.89, 885.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6890)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (267, 556, 1312)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3402)
[M::mem_pestat] mean and std.dev: (662.08, 504.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4447)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701106 sequences (100000112 bp) in 2.307 CPU sec, 2.311 real sec...
[M::mem_process_seqs] Processed 701936 reads in 205.992 CPU sec, 6.554 real sec
sorting block 64, #reads = 1074630 mem = 536880001 peak = 1009860608
[M::mem_process_seqs] Processed 705036 reads in 143.495 CPU sec, 4.555 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 286064, 29, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 383, 1439)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3975)
[M::mem_pestat] mean and std.dev: (729.63, 816.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5243)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 225, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 696)
[M::mem_pestat] mean and std.dev: (254.57, 131.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 877)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (241, 333, 741)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1741)
[M::mem_pestat] mean and std.dev: (417.59, 321.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2241)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 358, 861)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2211)
[M::mem_pestat] mean and std.dev: (590.58, 575.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2892)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 65, #reads = 1077470 mem = 536878387 peak = 1009860608
[M::process] read 700282 sequences (100000286 bp) in 3.246 CPU sec, 3.370 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 285584, 17, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (348, 614, 1802)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4710)
[M::mem_pestat] mean and std.dev: (969.00, 932.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6164)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 230, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 719)
[M::mem_pestat] mean and std.dev: (260.62, 135.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 907)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (407, 925, 2544)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6818)
[M::mem_pestat] mean and std.dev: (1228.00, 1517.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8955)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 367, 430)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 926)
[M::mem_pestat] mean and std.dev: (311.96, 171.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1174)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699746 sequences (100000141 bp) in 2.280 CPU sec, 2.289 real sec...
[M::mem_process_seqs] Processed 703102 reads in 195.689 CPU sec, 6.202 real sec
[M::process] read 699136 sequences (100000120 bp) in 2.184 CPU sec, 2.192 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 285533, 21, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 481, 1221)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3283)
[M::mem_pestat] mean and std.dev: (699.19, 592.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4314)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 233, 350)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 736)
[M::mem_pestat] mean and std.dev: (264.77, 138.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 929)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 370, 2020)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5722)
[M::mem_pestat] mean and std.dev: (921.90, 919.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7573)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 359, 558)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1294)
[M::mem_pestat] mean and std.dev: (310.23, 188.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1662)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700282 reads in 111.065 CPU sec, 3.755 real sec
sorting block 66, #reads = 1077721 mem = 536883202 peak = 1009860608
[M::mem_process_seqs] Processed 701106 reads in 275.906 CPU sec, 9.002 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 285092, 24, 22)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 487, 1024)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2752)
[M::mem_pestat] mean and std.dev: (584.06, 522.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3616)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 235, 352)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 740)
[M::mem_pestat] mean and std.dev: (266.51, 138.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 934)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (479, 741, 1469)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3449)
[M::mem_pestat] mean and std.dev: (774.59, 524.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4439)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 287, 1690)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4698)
[M::mem_pestat] mean and std.dev: (890.77, 931.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6202)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698894 sequences (100000097 bp) in 3.048 CPU sec, 3.143 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 284653, 19, 23)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (225, 619, 1004)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2562)
[M::mem_pestat] mean and std.dev: (688.59, 610.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3341)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 237, 354)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 744)
[M::mem_pestat] mean and std.dev: (267.77, 138.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 939)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (286, 452, 2083)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5677)
[M::mem_pestat] mean and std.dev: (1000.37, 1021.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7474)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (256, 331, 510)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1018)
[M::mem_pestat] mean and std.dev: (356.00, 162.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1272)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699746 reads in 217.849 CPU sec, 6.916 real sec
sorting block 67, #reads = 1079370 mem = 536879838 peak = 1009860608
[M::mem_process_seqs] Processed 699136 reads in 136.983 CPU sec, 4.319 real sec
[M::process] read 698672 sequences (100000247 bp) in 2.714 CPU sec, 2.787 real sec...
sorting block 68, #reads = 1077103 mem = 536879089 peak = 1009860608
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 284698, 21, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 437, 1040)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2698)
[M::mem_pestat] mean and std.dev: (593.86, 428.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3527)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 238, 356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 750)
[M::mem_pestat] mean and std.dev: (269.51, 140.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 947)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (767, 1731, 2490)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5936)
[M::mem_pestat] mean and std.dev: (1721.19, 1481.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7659)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (303, 417, 931)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2187)
[M::mem_pestat] mean and std.dev: (498.50, 327.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2815)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698452 sequences (100000078 bp) in 2.805 CPU sec, 2.923 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 284569, 16, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (243, 403, 989)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2481)
[M::mem_pestat] mean and std.dev: (547.36, 424.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3227)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 239, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 754)
[M::mem_pestat] mean and std.dev: (270.18, 140.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 952)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (636, 636, 2349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5775)
[M::mem_pestat] mean and std.dev: (1284.00, 1349.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7488)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 327, 1482)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4090)
[M::mem_pestat] mean and std.dev: (657.97, 617.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5394)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697614 sequences (100000157 bp) in 2.169 CPU sec, 2.174 real sec...
[M::mem_process_seqs] Processed 698894 reads in 193.456 CPU sec, 6.143 real sec
[M::mem_process_seqs] Processed 698672 reads in 136.118 CPU sec, 4.312 real sec
sorting block 69, #reads = 1076937 mem = 536880356 peak = 1009860608
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23, 284625, 24, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 211, 1139)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3111)
[M::mem_pestat] mean and std.dev: (495.05, 552.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4097)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 240, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 754)
[M::mem_pestat] mean and std.dev: (270.50, 140.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 952)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (361, 765, 3417)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9529)
[M::mem_pestat] mean and std.dev: (2061.61, 2562.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12585)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 353, 432)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 888)
[M::mem_pestat] mean and std.dev: (301.10, 122.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1116)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697430 sequences (100000088 bp) in 3.368 CPU sec, 3.516 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 283874, 27, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (264, 492, 2588)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7236)
[M::mem_pestat] mean and std.dev: (961.48, 1190.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9560)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 242, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 755)
[M::mem_pestat] mean and std.dev: (272.33, 140.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 953)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (456, 992, 2043)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5217)
[M::mem_pestat] mean and std.dev: (1523.74, 1517.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7594)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 419, 953)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2485)
[M::mem_pestat] mean and std.dev: (530.93, 467.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3251)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697494 sequences (100000093 bp) in 2.490 CPU sec, 2.500 real sec...
[M::mem_process_seqs] Processed 698452 reads in 200.599 CPU sec, 6.361 real sec
sorting block 70, #reads = 1076751 mem = 536876886 peak = 1009860608
[M::mem_process_seqs] Processed 697614 reads in 140.971 CPU sec, 4.480 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 283807, 26, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 341, 532)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1174)
[M::mem_pestat] mean and std.dev: (308.95, 148.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1495)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 243, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 756)
[M::mem_pestat] mean and std.dev: (272.50, 140.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 954)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 740, 1326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3590)
[M::mem_pestat] mean and std.dev: (930.46, 1012.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4980)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 326, 819)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2041)
[M::mem_pestat] mean and std.dev: (412.20, 364.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2652)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697028 sequences (100000209 bp) in 3.059 CPU sec, 3.230 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 283717, 37, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 351, 530)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1248)
[M::mem_pestat] mean and std.dev: (338.94, 226.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1607)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 242, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 756)
[M::mem_pestat] mean and std.dev: (272.25, 140.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 954)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (265, 591, 1794)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4852)
[M::mem_pestat] mean and std.dev: (1136.68, 1237.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6381)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (301, 451, 645)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1333)
[M::mem_pestat] mean and std.dev: (501.84, 310.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1746)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697206 sequences (100000039 bp) in 2.395 CPU sec, 2.404 real sec...
[M::mem_process_seqs] Processed 697430 reads in 203.163 CPU sec, 6.474 real sec
sorting block 71, #reads = 1074280 mem = 536878623 peak = 1009860608
[M::mem_process_seqs] Processed 697494 reads in 145.249 CPU sec, 4.628 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 283649, 28, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 358, 786)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1972)
[M::mem_pestat] mean and std.dev: (454.10, 453.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2565)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 242, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 753)
[M::mem_pestat] mean and std.dev: (272.27, 139.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 950)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (122, 849, 1420)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4016)
[M::mem_pestat] mean and std.dev: (843.77, 845.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5314)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 570, 744)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1786)
[M::mem_pestat] mean and std.dev: (518.55, 369.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2307)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 72, #reads = 1074266 mem = 536880229 peak = 1051762688
[M::process] read 696608 sequences (100000004 bp) in 3.021 CPU sec, 3.156 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 283748, 10, 21)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 394, 750)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1860)
[M::mem_pestat] mean and std.dev: (400.68, 366.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2415)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 242, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 750)
[M::mem_pestat] mean and std.dev: (271.42, 138.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 946)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 452, 1274)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3472)
[M::mem_pestat] mean and std.dev: (397.38, 370.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4571)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (255, 320, 1106)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2808)
[M::mem_pestat] mean and std.dev: (504.74, 404.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3659)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696730 sequences (100000030 bp) in 2.491 CPU sec, 2.494 real sec...
[M::mem_process_seqs] Processed 697028 reads in 206.116 CPU sec, 6.571 real sec
[M::mem_process_seqs] Processed 697206 reads in 147.037 CPU sec, 4.673 real sec
sorting block 73, #reads = 1073252 mem = 536879374 peak = 1051762688
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 283695, 21, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (241, 439, 777)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1849)
[M::mem_pestat] mean and std.dev: (499.00, 335.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2385)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 244, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 755)
[M::mem_pestat] mean and std.dev: (273.25, 139.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 952)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (378, 446, 5038)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 14358)
[M::mem_pestat] mean and std.dev: (1943.76, 2519.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 19018)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (240, 426, 803)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1929)
[M::mem_pestat] mean and std.dev: (408.03, 256.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2492)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696860 sequences (100000009 bp) in 3.243 CPU sec, 3.387 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 283265, 16, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 364, 624)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1494)
[M::mem_pestat] mean and std.dev: (428.57, 295.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1929)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 243, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 751)
[M::mem_pestat] mean and std.dev: (272.45, 139.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 947)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (261, 376, 1686)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4536)
[M::mem_pestat] mean and std.dev: (883.44, 938.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5961)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 393, 1180)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3092)
[M::mem_pestat] mean and std.dev: (610.19, 627.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4048)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696608 reads in 207.051 CPU sec, 6.594 real sec
[M::process] read 696610 sequences (100000238 bp) in 2.574 CPU sec, 2.594 real sec...
[M::mem_process_seqs] Processed 696730 reads in 146.794 CPU sec, 4.650 real sec
sorting block 74, #reads = 1072117 mem = 536878136 peak = 1051762688
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 283586, 20, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 271, 510)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1092)
[M::mem_pestat] mean and std.dev: (292.91, 160.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1383)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 243, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 750)
[M::mem_pestat] mean and std.dev: (271.44, 138.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 946)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (436, 689, 2531)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6721)
[M::mem_pestat] mean and std.dev: (1303.58, 1652.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8816)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 238, 784)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1954)
[M::mem_pestat] mean and std.dev: (498.66, 463.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2539)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696196 sequences (100000172 bp) in 3.024 CPU sec, 3.164 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 283102, 16, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 540, 658)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1548)
[M::mem_pestat] mean and std.dev: (497.65, 338.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1993)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 244, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 749)
[M::mem_pestat] mean and std.dev: (272.34, 138.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 944)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (240, 1875, 3946)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 11358)
[M::mem_pestat] mean and std.dev: (2262.56, 2427.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 15064)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 322, 646)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1548)
[M::mem_pestat] mean and std.dev: (363.89, 276.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1999)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696888 sequences (100000028 bp) in 2.162 CPU sec, 2.169 real sec...
[M::mem_process_seqs] Processed 696860 reads in 212.092 CPU sec, 6.766 real sec
sorting block 75, #reads = 1072124 mem = 536879877 peak = 1051762688
[M::mem_process_seqs] Processed 696610 reads in 148.211 CPU sec, 4.712 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 283397, 20, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (297, 410, 681)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1449)
[M::mem_pestat] mean and std.dev: (457.66, 272.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1833)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 244, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 749)
[M::mem_pestat] mean and std.dev: (272.64, 138.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 944)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 270, 832)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2128)
[M::mem_pestat] mean and std.dev: (463.74, 497.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2776)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (288, 380, 835)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1929)
[M::mem_pestat] mean and std.dev: (405.73, 252.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2476)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 76, #reads = 1072348 mem = 536879365 peak = 1051762688
[M::process] read 696408 sequences (100000270 bp) in 3.134 CPU sec, 3.277 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 283133, 25, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (264, 455, 633)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1371)
[M::mem_pestat] mean and std.dev: (368.64, 152.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1740)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 243, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 751)
[M::mem_pestat] mean and std.dev: (272.45, 139.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 947)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (325, 592, 668)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1354)
[M::mem_pestat] mean and std.dev: (494.96, 344.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1875)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (231, 642, 1435)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3843)
[M::mem_pestat] mean and std.dev: (800.56, 672.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5047)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696196 reads in 205.791 CPU sec, 6.552 real sec
[M::process] read 696550 sequences (100000104 bp) in 2.370 CPU sec, 2.376 real sec...
[M::mem_process_seqs] Processed 696888 reads in 145.950 CPU sec, 4.611 real sec
sorting block 77, #reads = 1071469 mem = 536877579 peak = 1051762688
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 283396, 31, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 479, 779)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1875)
[M::mem_pestat] mean and std.dev: (548.43, 452.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2423)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 245, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 761)
[M::mem_pestat] mean and std.dev: (274.86, 141.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 960)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (486, 746, 1307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2949)
[M::mem_pestat] mean and std.dev: (821.21, 575.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3770)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 423, 759)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1885)
[M::mem_pestat] mean and std.dev: (419.31, 331.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2448)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703396 sequences (100000014 bp) in 2.891 CPU sec, 2.957 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 283869, 22, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (142, 240, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 691)
[M::mem_pestat] mean and std.dev: (222.44, 99.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 874)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::process] read 708222 sequences (100000228 bp) in 2.410 CPU sec, 2.414 real sec...
[M::mem_pestat] (25, 50, 75) percentile: (163, 245, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 763)
[M::mem_pestat] mean and std.dev: (274.72, 141.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 963)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 854, 1617)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4501)
[M::mem_pestat] mean and std.dev: (734.56, 667.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5943)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (233, 585, 1234)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3236)
[M::mem_pestat] mean and std.dev: (784.56, 667.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4237)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696408 reads in 200.037 CPU sec, 6.321 real sec
[M::mem_process_seqs] Processed 696550 reads in 143.274 CPU sec, 4.559 real sec
sorting block 78, #reads = 1073001 mem = 536879322 peak = 1051762688
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 286040, 20, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 382, 1031)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2757)
[M::mem_pestat] mean and std.dev: (366.55, 280.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3620)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 224, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 687)
[M::mem_pestat] mean and std.dev: (252.53, 129.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 865)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (371, 557, 1834)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4760)
[M::mem_pestat] mean and std.dev: (937.15, 816.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6223)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 385, 750)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1864)
[M::mem_pestat] mean and std.dev: (467.23, 383.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2421)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 707626 sequences (100000188 bp) in 3.287 CPU sec, 3.408 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 287942, 16, 24)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 280, 1039)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2807)
[M::mem_pestat] mean and std.dev: (424.04, 419.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3691)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 211, 310)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 638)
[M::mem_pestat] mean and std.dev: (238.37, 120.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 802)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (324, 494, 2120)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5712)
[M::mem_pestat] mean and std.dev: (1214.47, 1576.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7520)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (233, 293, 1006)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2552)
[M::mem_pestat] mean and std.dev: (682.17, 672.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3370)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703396 reads in 220.198 CPU sec, 7.015 real sec
[M::process] read 705644 sequences (100000120 bp) in 2.576 CPU sec, 2.584 real sec...
sorting block 79, #reads = 1072831 mem = 536878539 peak = 1051762688
[M::mem_process_seqs] Processed 708222 reads in 152.780 CPU sec, 4.840 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 287728, 13, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (230, 420, 1341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3563)
[M::mem_pestat] mean and std.dev: (745.53, 779.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4674)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 213, 313)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 645)
[M::mem_pestat] mean and std.dev: (240.25, 121.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 811)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 520, 1062)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2752)
[M::mem_pestat] mean and std.dev: (464.45, 266.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3597)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 488, 1497)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4079)
[M::mem_pestat] mean and std.dev: (723.06, 578.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5370)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 80, #reads = 1075681 mem = 536879015 peak = 1051762688
[M::process] read 703544 sequences (100000203 bp) in 3.280 CPU sec, 3.412 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 286732, 19, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 338, 600)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1338)
[M::mem_pestat] mean and std.dev: (435.91, 312.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1707)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 218, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 668)
[M::mem_pestat] mean and std.dev: (246.26, 124.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 841)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 604, 2334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6616)
[M::mem_pestat] mean and std.dev: (1144.37, 1252.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8757)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 336, 611)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1413)
[M::mem_pestat] mean and std.dev: (426.00, 327.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1814)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703038 sequences (100000037 bp) in 2.517 CPU sec, 2.521 real sec...
[M::mem_process_seqs] Processed 707626 reads in 229.093 CPU sec, 7.300 real sec
[M::mem_process_seqs] Processed 705644 reads in 157.670 CPU sec, 5.012 real sec
sorting block 81, #reads = 1074457 mem = 536880657 peak = 1051762688
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 286502, 20, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 261, 882)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2208)
[M::mem_pestat] mean and std.dev: (540.92, 602.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2950)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 223, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 689)
[M::mem_pestat] mean and std.dev: (252.55, 128.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 868)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 529, 1441)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3861)
[M::mem_pestat] mean and std.dev: (693.85, 656.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5071)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 273, 798)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2046)
[M::mem_pestat] mean and std.dev: (350.36, 291.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2670)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702112 sequences (100000110 bp) in 2.996 CPU sec, 3.124 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 286253, 21, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 378, 1494)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4108)
[M::mem_pestat] mean and std.dev: (986.62, 1106.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5415)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 224, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 693)
[M::mem_pestat] mean and std.dev: (253.79, 130.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 873)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (251, 430, 791)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1871)
[M::mem_pestat] mean and std.dev: (373.74, 264.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2411)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 475, 794)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1970)
[M::mem_pestat] mean and std.dev: (387.95, 266.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2558)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701870 sequences (100000077 bp) in 2.426 CPU sec, 2.429 real sec...
[M::mem_process_seqs] Processed 703544 reads in 218.222 CPU sec, 6.955 real sec
[M::mem_process_seqs] Processed 703038 reads in 152.205 CPU sec, 4.845 real sec
sorting block 82, #reads = 1074502 mem = 536879484 peak = 1051762688
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 286050, 26, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 460, 1095)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2855)
[M::mem_pestat] mean and std.dev: (579.70, 470.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3735)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 227, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 709)
[M::mem_pestat] mean and std.dev: (257.33, 132.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 894)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 533, 1077)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2925)
[M::mem_pestat] mean and std.dev: (554.35, 432.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3849)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 375, 1171)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3103)
[M::mem_pestat] mean and std.dev: (492.03, 431.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4069)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701452 sequences (100000154 bp) in 3.625 CPU sec, 3.828 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (21, 286202, 23, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 295, 479)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1007)
[M::mem_pestat] mean and std.dev: (270.65, 109.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1271)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 228, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 713)
[M::mem_pestat] mean and std.dev: (258.98, 133.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 899)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (109, 242, 608)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1606)
[M::mem_pestat] mean and std.dev: (282.47, 278.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2105)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (236, 336, 694)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1610)
[M::mem_pestat] mean and std.dev: (465.33, 349.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2068)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702112 reads in 213.236 CPU sec, 6.793 real sec
[M::process] read 700828 sequences (100000222 bp) in 3.068 CPU sec, 3.132 real sec...
[M::mem_process_seqs] Processed 701870 reads in 148.174 CPU sec, 4.685 real sec
sorting block 83, #reads = 1073197 mem = 536877303 peak = 1051762688
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 285701, 26, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 436, 800)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2086)
[M::mem_pestat] mean and std.dev: (477.14, 352.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2729)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 230, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 719)
[M::mem_pestat] mean and std.dev: (259.97, 133.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 907)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (36, 508, 3279)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9765)
[M::mem_pestat] mean and std.dev: (1364.08, 1545.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13008)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 291, 1975)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5555)
[M::mem_pestat] mean and std.dev: (756.28, 987.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7345)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 84, #reads = 1076063 mem = 536878610 peak = 1051762688
[M::process] read 700592 sequences (100000179 bp) in 3.129 CPU sec, 3.251 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 285270, 25, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 267, 762)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1946)
[M::mem_pestat] mean and std.dev: (323.71, 235.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2538)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 232, 346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 726)
[M::mem_pestat] mean and std.dev: (262.00, 134.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 916)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (252, 746, 1657)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4467)
[M::mem_pestat] mean and std.dev: (890.04, 742.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5872)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 371, 697)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1745)
[M::mem_pestat] mean and std.dev: (343.03, 243.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2269)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701452 reads in 214.031 CPU sec, 6.835 real sec
[M::process] read 700106 sequences (100000296 bp) in 2.619 CPU sec, 2.638 real sec...
[M::mem_process_seqs] Processed 700828 reads in 150.616 CPU sec, 4.783 real sec
sorting block 85, #reads = 1075460 mem = 536880317 peak = 1051762688
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 285197, 25, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 486, 2546)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7218)
[M::mem_pestat] mean and std.dev: (765.52, 892.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9554)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 233, 349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 733)
[M::mem_pestat] mean and std.dev: (263.47, 135.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 925)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (564, 1488, 1799)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4269)
[M::mem_pestat] mean and std.dev: (1415.40, 843.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5504)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (284, 713, 987)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2393)
[M::mem_pestat] mean and std.dev: (617.55, 369.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3096)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699140 sequences (100000205 bp) in 3.298 CPU sec, 3.490 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 284930, 17, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (232, 475, 897)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2227)
[M::mem_pestat] mean and std.dev: (468.21, 316.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2892)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 236, 352)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 742)
[M::mem_pestat] mean and std.dev: (266.51, 138.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 937)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (276, 1314, 1765)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4743)
[M::mem_pestat] mean and std.dev: (986.25, 678.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6232)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (234, 346, 737)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1743)
[M::mem_pestat] mean and std.dev: (438.65, 337.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2246)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700592 reads in 217.579 CPU sec, 6.963 real sec
[M::process] read 698500 sequences (100000094 bp) in 2.536 CPU sec, 2.543 real sec...
[M::mem_process_seqs] Processed 700106 reads in 153.352 CPU sec, 4.858 real sec
sorting block 86, #reads = 1073723 mem = 536877302 peak = 1051762688
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 284300, 18, 23)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (233, 392, 754)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1796)
[M::mem_pestat] mean and std.dev: (429.85, 322.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2317)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 237, 352)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 738)
[M::mem_pestat] mean and std.dev: (266.86, 137.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 931)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (119, 484, 874)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2384)
[M::mem_pestat] mean and std.dev: (613.12, 571.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3139)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (261, 334, 2312)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6414)
[M::mem_pestat] mean and std.dev: (867.77, 1014.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8465)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698242 sequences (100000048 bp) in 2.927 CPU sec, 3.017 real sec...
[M::process] read 697722 sequences (100000159 bp) in 2.330 CPU sec, 2.334 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 284770, 27, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 285, 584)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1414)
[M::mem_pestat] mean and std.dev: (389.55, 320.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1829)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 238, 354)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 742)
[M::mem_pestat] mean and std.dev: (268.39, 137.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 936)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (337, 988, 2966)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8224)
[M::mem_pestat] mean and std.dev: (1746.56, 1844.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10853)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 372, 1126)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3010)
[M::mem_pestat] mean and std.dev: (599.45, 525.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3952)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699140 reads in 215.184 CPU sec, 6.892 real sec
sorting block 87, #reads = 1073467 mem = 536878006 peak = 1051762688
[M::mem_process_seqs] Processed 698500 reads in 147.708 CPU sec, 4.695 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 284175, 29, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (259, 645, 2479)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6919)
[M::mem_pestat] mean and std.dev: (1126.78, 1205.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9139)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 239, 355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 745)
[M::mem_pestat] mean and std.dev: (269.14, 138.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 940)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (100, 529, 1470)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4210)
[M::mem_pestat] mean and std.dev: (703.72, 699.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5580)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 538, 1065)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2741)
[M::mem_pestat] mean and std.dev: (544.45, 438.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3579)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697430 sequences (100000253 bp) in 2.957 CPU sec, 3.032 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 283730, 24, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (245, 415, 769)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1817)
[M::mem_pestat] mean and std.dev: (463.26, 387.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2341)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 240, 355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 743)
[M::mem_pestat] mean and std.dev: (269.72, 138.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 937)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (59, 615, 1460)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4262)
[M::mem_pestat] mean and std.dev: (769.77, 1069.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5663)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 343, 898)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2306)
[M::mem_pestat] mean and std.dev: (542.80, 609.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3010)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697786 sequences (100000176 bp) in 2.410 CPU sec, 2.416 real sec...
[M::mem_process_seqs] Processed 698242 reads in 208.668 CPU sec, 6.615 real sec
sorting block 88, #reads = 1072580 mem = 536886646 peak = 1051762688
[M::mem_process_seqs] Processed 697722 reads in 144.850 CPU sec, 4.602 real sec
sorting block 89, #reads = 1073030 mem = 536883699 peak = 1051762688
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 283892, 13, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (238, 340, 533)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1123)
[M::mem_pestat] mean and std.dev: (374.37, 216.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1418)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 241, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 750)
[M::mem_pestat] mean and std.dev: (271.15, 139.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 946)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (45, 318, 529)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1497)
[M::mem_pestat] mean and std.dev: (324.08, 350.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1981)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 562, 859)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2155)
[M::mem_pestat] mean and std.dev: (612.14, 502.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2803)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697074 sequences (100000084 bp) in 2.950 CPU sec, 3.033 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 284396, 18, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 340, 992)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2618)
[M::mem_pestat] mean and std.dev: (455.38, 419.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3431)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 241, 356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 746)
[M::mem_pestat] mean and std.dev: (270.00, 138.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 941)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (269, 483, 992)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2438)
[M::mem_pestat] mean and std.dev: (486.12, 351.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3161)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (321, 961, 2314)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6300)
[M::mem_pestat] mean and std.dev: (1484.77, 1353.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8293)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696374 sequences (100000043 bp) in 2.370 CPU sec, 2.376 real sec...
[M::mem_process_seqs] Processed 697430 reads in 202.789 CPU sec, 6.432 real sec
[M::mem_process_seqs] Processed 697786 reads in 144.477 CPU sec, 4.589 real sec
sorting block 90, #reads = 1073351 mem = 536878276 peak = 1051762688
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 283822, 28, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 441, 2015)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5635)
[M::mem_pestat] mean and std.dev: (1433.68, 1779.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8552)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 243, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 754)
[M::mem_pestat] mean and std.dev: (272.63, 140.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 951)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (346, 637, 1799)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4705)
[M::mem_pestat] mean and std.dev: (942.72, 981.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6158)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 212, 474)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1130)
[M::mem_pestat] mean and std.dev: (267.41, 164.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1458)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696460 sequences (100000115 bp) in 3.137 CPU sec, 3.243 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 283513, 18, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 317, 743)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1815)
[M::mem_pestat] mean and std.dev: (446.84, 347.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2351)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 245, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 755)
[M::mem_pestat] mean and std.dev: (273.94, 140.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 952)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 473, 899)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2343)
[M::mem_pestat] mean and std.dev: (531.53, 537.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3065)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (255, 554, 1319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3447)
[M::mem_pestat] mean and std.dev: (632.71, 510.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4511)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697140 sequences (100000063 bp) in 2.523 CPU sec, 2.527 real sec...
[M::mem_process_seqs] Processed 697074 reads in 210.063 CPU sec, 6.683 real sec
[M::mem_process_seqs] Processed 696374 reads in 148.608 CPU sec, 4.736 real sec
sorting block 91, #reads = 1071688 mem = 536881728 peak = 1051762688
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 283679, 23, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 226, 696)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1756)
[M::mem_pestat] mean and std.dev: (369.24, 387.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2286)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 245, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 760)
[M::mem_pestat] mean and std.dev: (274.63, 141.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 959)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 472, 887)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2361)
[M::mem_pestat] mean and std.dev: (480.00, 391.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3098)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 346, 575)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1277)
[M::mem_pestat] mean and std.dev: (364.03, 187.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1628)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701728 sequences (100000080 bp) in 3.381 CPU sec, 3.560 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 283603, 29, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 302, 709)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1779)
[M::mem_pestat] mean and std.dev: (491.70, 424.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2314)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 242, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 753)
[M::mem_pestat] mean and std.dev: (271.92, 140.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 950)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (142, 802, 1526)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4294)
[M::mem_pestat] mean and std.dev: (1259.10, 1422.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6949)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 564, 1085)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2863)
[M::mem_pestat] mean and std.dev: (637.17, 608.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3752)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705968 sequences (100000125 bp) in 2.412 CPU sec, 2.418 real sec...
[M::mem_process_seqs] Processed 696460 reads in 221.040 CPU sec, 7.062 real sec
sorting block 92, #reads = 1073678 mem = 536879815 peak = 1051762688
[M::mem_process_seqs] Processed 697140 reads in 159.014 CPU sec, 5.090 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 285338, 22, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 443, 954)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2538)
[M::mem_pestat] mean and std.dev: (609.85, 622.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3330)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 228, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 707)
[M::mem_pestat] mean and std.dev: (258.26, 133.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 891)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (324, 1010, 1407)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3573)
[M::mem_pestat] mean and std.dev: (1011.77, 785.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4656)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 332, 950)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2430)
[M::mem_pestat] mean and std.dev: (516.02, 462.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3170)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 93, #reads = 1072618 mem = 536885302 peak = 1051762688
[M::process] read 704468 sequences (100000174 bp) in 3.574 CPU sec, 3.801 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20, 287155, 17, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (276, 393, 1060)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2628)
[M::mem_pestat] mean and std.dev: (442.41, 313.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3412)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 218, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 668)
[M::mem_pestat] mean and std.dev: (246.20, 125.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 841)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 238, 1193)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3253)
[M::mem_pestat] mean and std.dev: (554.80, 774.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4283)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 326, 491)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1125)
[M::mem_pestat] mean and std.dev: (331.97, 251.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1442)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703188 sequences (100000192 bp) in 2.475 CPU sec, 2.501 real sec...
[M::mem_process_seqs] Processed 701728 reads in 231.948 CPU sec, 7.416 real sec
[M::mem_process_seqs] Processed 705968 reads in 153.116 CPU sec, 4.896 real sec
sorting block 94, #reads = 1070264 mem = 536885222 peak = 1051762688
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 286748, 7, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (372, 626, 1457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3627)
[M::mem_pestat] mean and std.dev: (816.36, 645.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4712)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 222, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 685)
[M::mem_pestat] mean and std.dev: (250.69, 128.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 863)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (295, 423, 437)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (11, 721)
[M::mem_pestat] mean and std.dev: (348.08, 118.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 863)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 702064 sequences (100000221 bp) in 3.195 CPU sec, 3.395 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 286706, 16, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (285, 567, 833)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1929)
[M::mem_pestat] mean and std.dev: (486.00, 357.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2477)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 224, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 692)
[M::mem_pestat] mean and std.dev: (253.48, 129.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 872)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (338, 2038, 7573)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 22043)
[M::mem_pestat] mean and std.dev: (2889.69, 3272.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 29278)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 343, 637)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1467)
[M::mem_pestat] mean and std.dev: (408.30, 249.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1882)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704468 reads in 213.122 CPU sec, 6.858 real sec
[M::process] read 701254 sequences (100000257 bp) in 2.610 CPU sec, 2.664 real sec...
[M::mem_process_seqs] Processed 703188 reads in 147.080 CPU sec, 4.717 real sec
sorting block 95, #reads = 1079431 mem = 536882118 peak = 1051762688
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23, 285720, 22, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 398, 1063)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2775)
[M::mem_pestat] mean and std.dev: (591.62, 585.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3631)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 229, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 709)
[M::mem_pestat] mean and std.dev: (257.47, 131.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 894)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (104, 325, 1295)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3677)
[M::mem_pestat] mean and std.dev: (636.71, 723.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4868)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (265, 407, 2409)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6697)
[M::mem_pestat] mean and std.dev: (1011.84, 1015.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8841)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700614 sequences (100000292 bp) in 3.877 CPU sec, 4.128 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 285731, 13, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (331, 478, 1619)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4195)
[M::mem_pestat] mean and std.dev: (746.22, 590.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5483)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 231, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 714)
[M::mem_pestat] mean and std.dev: (260.04, 132.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 900)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 503, 737)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1905)
[M::mem_pestat] mean and std.dev: (377.09, 243.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2489)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 275, 775)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1981)
[M::mem_pestat] mean and std.dev: (362.61, 379.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2584)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702064 reads in 204.740 CPU sec, 6.576 real sec
sorting block 96, #reads = 1080162 mem = 536886380 peak = 1051762688
[M::mem_process_seqs] Processed 701254 reads in 142.437 CPU sec, 4.524 real sec
[M::process] read 700376 sequences (100000013 bp) in 3.214 CPU sec, 3.387 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 286083, 22, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 279, 794)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1988)
[M::mem_pestat] mean and std.dev: (511.97, 504.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2585)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 233, 345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 721)
[M::mem_pestat] mean and std.dev: (261.68, 133.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 909)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 934, 1470)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3982)
[M::mem_pestat] mean and std.dev: (993.76, 997.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5238)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (275, 481, 809)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1877)
[M::mem_pestat] mean and std.dev: (583.89, 467.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2453)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 97, #reads = 1078912 mem = 536877023 peak = 1051762688
[M::process] read 700316 sequences (100000234 bp) in 3.198 CPU sec, 3.364 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 285414, 21, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 376, 818)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2054)
[M::mem_pestat] mean and std.dev: (468.00, 380.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2672)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 234, 348)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 730)
[M::mem_pestat] mean and std.dev: (263.56, 134.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 921)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (139, 441, 1860)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5302)
[M::mem_pestat] mean and std.dev: (984.63, 1469.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7023)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (251, 707, 1550)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4148)
[M::mem_pestat] mean and std.dev: (1041.85, 983.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5447)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700614 reads in 210.904 CPU sec, 6.752 real sec
[M::mem_process_seqs] Processed 700376 reads in 148.022 CPU sec, 4.700 real sec
[M::process] read 700680 sequences (100000270 bp) in 2.594 CPU sec, 2.676 real sec...
sorting block 98, #reads = 1080193 mem = 536877285 peak = 1051762688
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 285199, 24, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 224, 308)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 622)
[M::mem_pestat] mean and std.dev: (230.06, 100.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 779)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 235, 350)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 734)
[M::mem_pestat] mean and std.dev: (264.76, 135.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 926)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (349, 454, 1041)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2425)
[M::mem_pestat] mean and std.dev: (532.48, 360.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3117)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 248, 1249)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3293)
[M::mem_pestat] mean and std.dev: (339.12, 334.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4315)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700254 sequences (100000110 bp) in 3.549 CPU sec, 3.817 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23, 285628, 22, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 305, 1087)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2821)
[M::mem_pestat] mean and std.dev: (569.52, 449.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3688)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 233, 346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 726)
[M::mem_pestat] mean and std.dev: (262.24, 134.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 916)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 500, 919)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2295)
[M::mem_pestat] mean and std.dev: (558.50, 395.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2983)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 278, 1269)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3377)
[M::mem_pestat] mean and std.dev: (579.48, 740.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4431)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700316 reads in 208.725 CPU sec, 6.651 real sec
[M::process] read 699346 sequences (100000057 bp) in 2.419 CPU sec, 2.464 real sec...
[M::mem_process_seqs] Processed 700680 reads in 142.837 CPU sec, 4.527 real sec
sorting block 99, #reads = 1075974 mem = 536877348 peak = 1051762688
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 285540, 23, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 243, 705)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1773)
[M::mem_pestat] mean and std.dev: (366.04, 294.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2307)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 235, 349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 733)
[M::mem_pestat] mean and std.dev: (264.16, 135.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 925)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (397, 1108, 1349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3253)
[M::mem_pestat] mean and std.dev: (771.53, 542.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4205)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 312, 495)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1139)
[M::mem_pestat] mean and std.dev: (354.39, 243.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1461)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700114 sequences (100000214 bp) in 2.904 CPU sec, 3.001 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 284943, 24, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (133, 224, 916)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2482)
[M::mem_pestat] mean and std.dev: (404.03, 478.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3265)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 237, 351)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 735)
[M::mem_pestat] mean and std.dev: (265.94, 135.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 927)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (435, 663, 2065)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5325)
[M::mem_pestat] mean and std.dev: (829.75, 706.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6955)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (231, 405, 675)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1563)
[M::mem_pestat] mean and std.dev: (449.49, 282.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2007)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700254 reads in 192.325 CPU sec, 6.112 real sec
[M::process] read 700674 sequences (100000121 bp) in 2.289 CPU sec, 2.284 real sec...
sorting block 100, #reads = 1078595 mem = 536878999 peak = 1051762688
[M::mem_process_seqs] Processed 699346 reads in 132.991 CPU sec, 4.207 real sec
sorting block 101, #reads = 1078824 mem = 536878471 peak = 1051762688
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 284683, 30, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 296, 938)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2512)
[M::mem_pestat] mean and std.dev: (546.36, 516.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3299)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 234, 346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 724)
[M::mem_pestat] mean and std.dev: (262.25, 133.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 913)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (374, 1035, 3732)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10448)
[M::mem_pestat] mean and std.dev: (2205.23, 2988.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14160)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 552, 1561)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4255)
[M::mem_pestat] mean and std.dev: (766.87, 778.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5602)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699376 sequences (100000048 bp) in 2.870 CPU sec, 2.951 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 285045, 21, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 302, 818)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2106)
[M::mem_pestat] mean and std.dev: (430.20, 374.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2750)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 233, 345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 723)
[M::mem_pestat] mean and std.dev: (261.42, 133.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 912)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (12, 516, 971)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2889)
[M::mem_pestat] mean and std.dev: (655.05, 665.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3848)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 303, 606)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1466)
[M::mem_pestat] mean and std.dev: (405.91, 277.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1896)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699342 sequences (100000165 bp) in 2.180 CPU sec, 2.183 real sec...
[M::mem_process_seqs] Processed 700114 reads in 193.396 CPU sec, 6.128 real sec
[M::mem_process_seqs] Processed 700674 reads in 136.043 CPU sec, 4.322 real sec
sorting block 102, #reads = 1077036 mem = 536879348 peak = 1051762688
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 284296, 18, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (240, 381, 1632)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4416)
[M::mem_pestat] mean and std.dev: (907.46, 866.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5808)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 238, 354)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 744)
[M::mem_pestat] mean and std.dev: (267.24, 136.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 939)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (94, 1243, 2777)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8143)
[M::mem_pestat] mean and std.dev: (1483.78, 1442.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10826)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (332, 977, 2444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6668)
[M::mem_pestat] mean and std.dev: (1161.75, 1031.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8780)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698806 sequences (100000061 bp) in 2.859 CPU sec, 2.940 real sec...
[M::process] read 698508 sequences (100000273 bp) in 2.076 CPU sec, 2.083 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 284547, 25, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 332, 583)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1437)
[M::mem_pestat] mean and std.dev: (315.38, 248.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1864)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 237, 353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 741)
[M::mem_pestat] mean and std.dev: (267.18, 137.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 935)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 374, 1272)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3510)
[M::mem_pestat] mean and std.dev: (654.42, 680.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4629)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 436, 792)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1980)
[M::mem_pestat] mean and std.dev: (498.90, 387.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2574)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699376 reads in 198.536 CPU sec, 6.294 real sec
[M::mem_process_seqs] Processed 699342 reads in 138.504 CPU sec, 4.402 real sec
sorting block 103, #reads = 1075577 mem = 536878690 peak = 1051762688
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 283800, 31, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 324, 1124)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2992)
[M::mem_pestat] mean and std.dev: (738.29, 761.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3926)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 239, 355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 745)
[M::mem_pestat] mean and std.dev: (268.57, 137.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 940)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (560, 1355, 3478)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9314)
[M::mem_pestat] mean and std.dev: (2008.52, 1871.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12232)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 310, 543)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1195)
[M::mem_pestat] mean and std.dev: (376.82, 212.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1521)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698120 sequences (100000271 bp) in 3.273 CPU sec, 3.453 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 284415, 26, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (130, 373, 513)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1279)
[M::mem_pestat] mean and std.dev: (357.67, 305.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1662)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 239, 353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 739)
[M::mem_pestat] mean and std.dev: (268.47, 137.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 932)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (271, 561, 1362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3544)
[M::mem_pestat] mean and std.dev: (791.65, 734.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4635)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 346, 565)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1373)
[M::mem_pestat] mean and std.dev: (375.35, 278.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1777)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698806 reads in 200.697 CPU sec, 6.532 real sec
[M::process] read 697652 sequences (100000176 bp) in 2.336 CPU sec, 2.343 real sec...
sorting block 104, #reads = 1073325 mem = 536885020 peak = 1051762688
[M::mem_process_seqs] Processed 698508 reads in 139.484 CPU sec, 4.411 real sec
sorting block 105, #reads = 1073021 mem = 536878172 peak = 1051762688
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 283860, 40, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 362, 1208)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3206)
[M::mem_pestat] mean and std.dev: (587.62, 588.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4205)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 238, 349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 727)
[M::mem_pestat] mean and std.dev: (266.16, 135.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 916)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (368, 641, 972)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2180)
[M::mem_pestat] mean and std.dev: (585.76, 397.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2784)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (239, 401, 846)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2060)
[M::mem_pestat] mean and std.dev: (539.21, 436.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2667)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697696 sequences (100000051 bp) in 2.648 CPU sec, 2.697 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 283892, 23, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 360, 877)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2261)
[M::mem_pestat] mean and std.dev: (372.89, 286.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2953)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::process] read 697486 sequences (100000123 bp) in 2.289 CPU sec, 2.294 real sec...
[M::mem_pestat] (25, 50, 75) percentile: (161, 240, 355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 743)
[M::mem_pestat] mean and std.dev: (269.69, 138.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 937)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 546, 1837)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5159)
[M::mem_pestat] mean and std.dev: (1232.22, 1482.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7163)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (274, 408, 977)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2383)
[M::mem_pestat] mean and std.dev: (541.79, 513.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3086)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698120 reads in 196.896 CPU sec, 6.236 real sec
[M::mem_process_seqs] Processed 697652 reads in 134.842 CPU sec, 4.282 real sec
sorting block 106, #reads = 1072753 mem = 536883981 peak = 1051762688
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 283934, 22, 24)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 390, 947)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2417)
[M::mem_pestat] mean and std.dev: (526.33, 428.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3152)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 239, 356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 746)
[M::mem_pestat] mean and std.dev: (269.73, 138.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 941)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (409, 687, 1326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3160)
[M::mem_pestat] mean and std.dev: (711.45, 449.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4077)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (271, 503, 718)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1612)
[M::mem_pestat] mean and std.dev: (424.75, 253.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2059)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697448 sequences (100000095 bp) in 2.392 CPU sec, 2.453 real sec...
[M::process] read 697962 sequences (100000214 bp) in 1.800 CPU sec, 1.798 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 283636, 23, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (229, 388, 1215)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3187)
[M::mem_pestat] mean and std.dev: (523.00, 516.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4173)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 240, 356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 744)
[M::mem_pestat] mean and std.dev: (269.95, 138.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 938)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (275, 479, 1305)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3365)
[M::mem_pestat] mean and std.dev: (534.71, 464.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4395)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 238, 415)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 847)
[M::mem_pestat] mean and std.dev: (276.69, 134.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1063)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697696 reads in 192.356 CPU sec, 6.111 real sec
[M::mem_process_seqs] Processed 697486 reads in 137.515 CPU sec, 4.383 real sec
sorting block 107, #reads = 1071900 mem = 536878473 peak = 1051762688
[M::process] read 709242 sequences (100000277 bp) in 2.497 CPU sec, 2.542 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 283686, 20, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 417, 1405)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3919)
[M::mem_pestat] mean and std.dev: (729.11, 731.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5176)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 241, 356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 744)
[M::mem_pestat] mean and std.dev: (270.19, 137.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 938)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 509, 1176)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3222)
[M::mem_pestat] mean and std.dev: (580.05, 543.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4245)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (277, 355, 1183)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2995)
[M::mem_pestat] mean and std.dev: (569.69, 597.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3901)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 709312 sequences (100000081 bp) in 1.731 CPU sec, 1.804 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 283257, 20, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 350, 627)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1463)
[M::mem_pestat] mean and std.dev: (375.23, 262.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1881)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 239, 354)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 740)
[M::mem_pestat] mean and std.dev: (268.62, 138.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 933)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (253, 442, 864)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2086)
[M::mem_pestat] mean and std.dev: (441.06, 367.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2697)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (237, 303, 705)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1641)
[M::mem_pestat] mean and std.dev: (354.88, 191.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2109)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697448 reads in 205.285 CPU sec, 6.525 real sec
sorting block 108, #reads = 1069840 mem = 536878898 peak = 1051762688
[M::mem_process_seqs] Processed 697962 reads in 152.452 CPU sec, 4.883 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 288107, 16, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 332, 555)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1367)
[M::mem_pestat] mean and std.dev: (368.89, 289.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1773)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 209, 306)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 628)
[M::mem_pestat] mean and std.dev: (235.71, 118.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 789)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (399, 868, 2568)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6906)
[M::mem_pestat] mean and std.dev: (1118.53, 1027.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9075)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 359, 735)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1763)
[M::mem_pestat] mean and std.dev: (424.00, 280.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2277)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 707760 sequences (100000262 bp) in 2.563 CPU sec, 2.621 real sec...
[M::process] read 706688 sequences (100000086 bp) in 2.100 CPU sec, 2.103 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 288188, 17, 23)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (232, 419, 950)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2386)
[M::mem_pestat] mean and std.dev: (430.54, 359.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3104)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 209, 307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 631)
[M::mem_pestat] mean and std.dev: (236.03, 118.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 793)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 864, 1940)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5404)
[M::mem_pestat] mean and std.dev: (1003.44, 867.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7136)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (241, 291, 1218)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3172)
[M::mem_pestat] mean and std.dev: (489.86, 412.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4149)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 709242 reads in 214.066 CPU sec, 6.812 real sec
sorting block 109, #reads = 1063995 mem = 536879887 peak = 1051762688
[M::mem_process_seqs] Processed 709312 reads in 145.451 CPU sec, 4.627 real sec
sorting block 110, #reads = 1072413 mem = 536880177 peak = 1051762688
[M::process] read 705338 sequences (100000167 bp) in 2.383 CPU sec, 2.437 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 287614, 22, 19)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 345, 502)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1138)
[M::mem_pestat] mean and std.dev: (340.34, 168.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1456)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 213, 315)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 651)
[M::mem_pestat] mean and std.dev: (241.11, 121.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 819)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (121, 764, 1281)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3601)
[M::mem_pestat] mean and std.dev: (836.00, 783.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4761)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 305, 687)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1609)
[M::mem_pestat] mean and std.dev: (451.39, 375.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2070)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704006 sequences (100000241 bp) in 2.290 CPU sec, 2.298 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 287537, 30, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (144, 350, 1179)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3249)
[M::mem_pestat] mean and std.dev: (524.54, 500.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4284)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 216, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 667)
[M::mem_pestat] mean and std.dev: (245.28, 124.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 840)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (242, 762, 1962)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5402)
[M::mem_pestat] mean and std.dev: (1027.21, 930.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7122)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 299, 903)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2341)
[M::mem_pestat] mean and std.dev: (474.36, 434.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3060)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 707760 reads in 190.792 CPU sec, 6.038 real sec
[M::mem_process_seqs] Processed 706688 reads in 131.912 CPU sec, 4.195 real sec
sorting block 111, #reads = 1074824 mem = 536878807 peak = 1051762688
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 287102, 17, 23)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 306, 1008)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2670)
[M::mem_pestat] mean and std.dev: (557.55, 533.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3501)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 220, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 678)
[M::mem_pestat] mean and std.dev: (248.88, 126.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 854)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (295, 651, 1845)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4945)
[M::mem_pestat] mean and std.dev: (927.67, 1003.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6495)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 266, 1146)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2988)
[M::mem_pestat] mean and std.dev: (607.78, 532.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3909)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703522 sequences (100000066 bp) in 2.877 CPU sec, 2.919 real sec...
[M::process] read 702152 sequences (100000170 bp) in 2.140 CPU sec, 2.145 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (18, 286723, 17, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (139, 334, 839)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2239)
[M::mem_pestat] mean and std.dev: (491.18, 499.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2939)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 223, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 692)
[M::mem_pestat] mean and std.dev: (252.36, 128.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 872)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 441, 820)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2090)
[M::mem_pestat] mean and std.dev: (362.00, 233.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2725)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (278, 1068, 3276)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9272)
[M::mem_pestat] mean and std.dev: (1818.03, 2365.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12270)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 705338 reads in 194.841 CPU sec, 6.162 real sec
sorting block 112, #reads = 1075188 mem = 536879977 peak = 1051762688
[M::process] read 703140 sequences (100000014 bp) in 2.127 CPU sec, 2.134 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 286362, 14, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 283, 410)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 926)
[M::mem_pestat] mean and std.dev: (276.68, 150.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1184)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 226, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 704)
[M::mem_pestat] mean and std.dev: (255.04, 130.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 888)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (10, 830, 2899)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8677)
[M::mem_pestat] mean and std.dev: (1976.14, 2829.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13295)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 206, 668)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1688)
[M::mem_pestat] mean and std.dev: (258.79, 181.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2198)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703522 reads in 107.023 CPU sec, 3.390 real sec
[M::mem_process_seqs] Processed 704006 reads in 264.816 CPU sec, 8.415 real sec
sorting block 113, #reads = 1074044 mem = 536882556 peak = 1051762688
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 285755, 32, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 342, 584)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1324)
[M::mem_pestat] mean and std.dev: (431.18, 320.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1714)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 228, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 715)
[M::mem_pestat] mean and std.dev: (258.36, 132.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 902)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 885, 2588)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7442)
[M::mem_pestat] mean and std.dev: (1237.47, 1269.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9869)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 334, 535)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1223)
[M::mem_pestat] mean and std.dev: (366.86, 246.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1567)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701996 sequences (100000181 bp) in 2.818 CPU sec, 2.877 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 285905, 26, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 286, 423)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 849)
[M::mem_pestat] mean and std.dev: (281.53, 111.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1062)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 225, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 705)
[M::mem_pestat] mean and std.dev: (255.92, 131.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 889)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (264, 410, 1121)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2835)
[M::mem_pestat] mean and std.dev: (595.87, 546.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3692)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 314, 619)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1439)
[M::mem_pestat] mean and std.dev: (497.00, 365.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1960)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702258 sequences (100000125 bp) in 2.040 CPU sec, 2.047 real sec...
[M::mem_process_seqs] Processed 702152 reads in 215.870 CPU sec, 6.841 real sec
sorting block 114, #reads = 1073026 mem = 536879778 peak = 1051762688
[M::mem_process_seqs] Processed 703140 reads in 136.954 CPU sec, 4.331 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 285591, 22, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (252, 316, 491)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 969)
[M::mem_pestat] mean and std.dev: (359.13, 145.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1208)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 229, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 719)
[M::mem_pestat] mean and std.dev: (259.71, 133.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 907)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (53, 441, 1523)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4463)
[M::mem_pestat] mean and std.dev: (924.50, 1105.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5933)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (302, 977, 1902)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5102)
[M::mem_pestat] mean and std.dev: (915.85, 698.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6702)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702418 sequences (100000175 bp) in 3.036 CPU sec, 3.124 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 285499, 22, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (128, 314, 860)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2324)
[M::mem_pestat] mean and std.dev: (422.23, 377.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3056)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 228, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 712)
[M::mem_pestat] mean and std.dev: (258.03, 132.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 898)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (127, 1099, 1679)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4783)
[M::mem_pestat] mean and std.dev: (1187.27, 1241.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6335)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 282, 416)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 944)
[M::mem_pestat] mean and std.dev: (276.41, 163.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1208)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700480 sequences (100000245 bp) in 2.280 CPU sec, 2.275 real sec...
[M::mem_process_seqs] Processed 701996 reads in 184.376 CPU sec, 5.812 real sec
sorting block 115, #reads = 1072160 mem = 536882078 peak = 1051762688
[M::mem_process_seqs] Processed 702258 reads in 209.137 CPU sec, 6.620 real sec
sorting block 116, #reads = 1074253 mem = 536883487 peak = 1051762688
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 285364, 17, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 345, 1322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3556)
[M::mem_pestat] mean and std.dev: (653.08, 688.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4673)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 227, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 694)
[M::mem_pestat] mean and std.dev: (255.07, 129.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 874)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (272, 532, 1707)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4577)
[M::mem_pestat] mean and std.dev: (907.18, 845.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6012)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 426, 1754)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4820)
[M::mem_pestat] mean and std.dev: (929.11, 918.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6353)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698664 sequences (100000179 bp) in 2.755 CPU sec, 2.789 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 284173, 20, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 484, 546)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1222)
[M::mem_pestat] mean and std.dev: (361.70, 195.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1560)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 233, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 718)
[M::mem_pestat] mean and std.dev: (261.32, 133.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 905)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (510, 1083, 1672)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3996)
[M::mem_pestat] mean and std.dev: (1083.84, 825.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5158)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 256, 1167)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3121)
[M::mem_pestat] mean and std.dev: (684.84, 706.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4098)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698118 sequences (100000065 bp) in 2.280 CPU sec, 2.290 real sec...
[M::mem_process_seqs] Processed 702418 reads in 188.113 CPU sec, 5.943 real sec
[M::process] read 697840 sequences (100000253 bp) in 1.785 CPU sec, 1.793 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 283934, 23, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 1125, 2852)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8120)
[M::mem_pestat] mean and std.dev: (1056.88, 1048.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10754)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 238, 352)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 736)
[M::mem_pestat] mean and std.dev: (266.78, 135.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 928)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (113, 287, 2542)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7400)
[M::mem_pestat] mean and std.dev: (1092.32, 1345.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9829)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 243, 586)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1318)
[M::mem_pestat] mean and std.dev: (407.70, 302.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1684)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698664 reads in 104.397 CPU sec, 3.358 real sec
sorting block 117, #reads = 1072972 mem = 536881198 peak = 1051762688
[M::mem_process_seqs] Processed 700480 reads in 255.160 CPU sec, 8.143 real sec
sorting block 118, #reads = 1072507 mem = 536884824 peak = 1109172224
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 283629, 17, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (358, 616, 1097)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2575)
[M::mem_pestat] mean and std.dev: (629.08, 386.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3314)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 239, 351)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 731)
[M::mem_pestat] mean and std.dev: (266.53, 133.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 921)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (423, 606, 1744)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4386)
[M::mem_pestat] mean and std.dev: (896.71, 691.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5707)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (262, 372, 778)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1810)
[M::mem_pestat] mean and std.dev: (459.74, 323.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2326)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697672 sequences (100000154 bp) in 2.241 CPU sec, 2.315 real sec...
[M::process] read 697186 sequences (100000073 bp) in 1.650 CPU sec, 1.643 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 284093, 15, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (226, 417, 916)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2296)
[M::mem_pestat] mean and std.dev: (623.06, 524.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2986)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 239, 351)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 731)
[M::mem_pestat] mean and std.dev: (266.94, 134.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 921)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (310, 676, 1485)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3835)
[M::mem_pestat] mean and std.dev: (978.87, 762.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5010)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 357, 614)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1446)
[M::mem_pestat] mean and std.dev: (396.12, 296.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1862)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698118 reads in 205.427 CPU sec, 6.536 real sec
[M::mem_process_seqs] Processed 697840 reads in 134.306 CPU sec, 4.287 real sec
sorting block 119, #reads = 1072137 mem = 536881847 peak = 1109172224
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 283161, 15, 24)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (271, 811, 1343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3487)
[M::mem_pestat] mean and std.dev: (697.84, 566.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4559)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 239, 348)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 722)
[M::mem_pestat] mean and std.dev: (265.30, 132.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 909)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (257, 1406, 1790)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4856)
[M::mem_pestat] mean and std.dev: (1038.57, 854.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6389)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 302, 546)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1216)
[M::mem_pestat] mean and std.dev: (343.67, 215.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1551)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696320 sequences (100000101 bp) in 2.421 CPU sec, 2.488 real sec...
[M::process] read 696140 sequences (100000260 bp) in 2.090 CPU sec, 2.085 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 284107, 35, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 282, 623)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1471)
[M::mem_pestat] mean and std.dev: (367.67, 294.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1895)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 242, 353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 735)
[M::mem_pestat] mean and std.dev: (268.23, 134.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 926)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 648, 1102)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2932)
[M::mem_pestat] mean and std.dev: (659.62, 580.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3847)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (299, 333, 930)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2192)
[M::mem_pestat] mean and std.dev: (490.69, 368.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2823)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697672 reads in 180.027 CPU sec, 5.700 real sec
sorting block 120, #reads = 1071752 mem = 536880810 peak = 1109172224
[M::mem_process_seqs] Processed 697186 reads in 125.767 CPU sec, 3.990 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 283686, 24, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (121, 470, 2339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6775)
[M::mem_pestat] mean and std.dev: (637.82, 730.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8993)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 243, 353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 733)
[M::mem_pestat] mean and std.dev: (268.93, 134.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 923)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (570, 986, 5496)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 15348)
[M::mem_pestat] mean and std.dev: (2521.71, 2777.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 20274)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 299, 452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 958)
[M::mem_pestat] mean and std.dev: (307.68, 150.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1211)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695962 sequences (100000276 bp) in 2.435 CPU sec, 2.506 real sec...
[M::process] read 695744 sequences (100000299 bp) in 1.740 CPU sec, 1.736 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 283223, 21, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 374, 722)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1842)
[M::mem_pestat] mean and std.dev: (316.37, 213.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2402)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 245, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 752)
[M::mem_pestat] mean and std.dev: (273.28, 138.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 948)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (431, 745, 1688)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4202)
[M::mem_pestat] mean and std.dev: (904.11, 909.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5459)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (258, 526, 1305)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3399)
[M::mem_pestat] mean and std.dev: (748.16, 645.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4446)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696320 reads in 184.912 CPU sec, 5.871 real sec
sorting block 121, #reads = 1072759 mem = 536883787 peak = 1109172224
[M::mem_process_seqs] Processed 696140 reads in 130.625 CPU sec, 4.393 real sec
sorting block 122, #reads = 1072753 mem = 536880165 peak = 1109172224
[M::process] read 605632 sequences (86913132 bp) in 2.084 CPU sec, 2.145 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 246556, 27, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (241, 420, 1565)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4213)
[M::mem_pestat] mean and std.dev: (860.38, 798.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5537)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 244, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 760)
[M::mem_pestat] mean and std.dev: (273.70, 140.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 959)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (50, 491, 1161)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3383)
[M::mem_pestat] mean and std.dev: (792.46, 933.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4527)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (292, 365, 997)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2407)
[M::mem_pestat] mean and std.dev: (527.66, 428.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3112)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 605632 reads in 89.190 CPU sec, 2.887 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 283138, 24, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (235, 312, 1300)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3430)
[M::mem_pestat] mean and std.dev: (566.66, 496.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4495)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 246, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 752)
[M::mem_pestat] mean and std.dev: (273.75, 138.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 948)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 341, 759)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1889)
[M::mem_pestat] mean and std.dev: (429.96, 407.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2454)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (253, 322, 823)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1963)
[M::mem_pestat] mean and std.dev: (432.10, 306.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2533)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 283124, 19, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (254, 579, 879)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2129)
[M::mem_pestat] mean and std.dev: (566.05, 400.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2754)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 247, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 762)
[M::mem_pestat] mean and std.dev: (275.71, 141.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 961)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (114, 666, 1328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3756)
[M::mem_pestat] mean and std.dev: (510.60, 496.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4970)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (273, 578, 809)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1881)
[M::mem_pestat] mean and std.dev: (541.88, 356.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2417)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695962 reads in 262.008 CPU sec, 8.645 real sec
sorting block 123, #reads = 1071535 mem = 536880266 peak = 1109172224
[M::mem_process_seqs] Processed 695744 reads in 199.402 CPU sec, 6.450 real sec
sorting block 124, #reads = 1073298 mem = 536878392 peak = 1203912704
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000c06f2
  features: bfebfbff 7ffefbff
  extended: f3bfb7ef fb417ffe
  amd bits: 2c100800 00000121
     brand: INTEL(R) XEON(R) PLATINUM 8559C
threads: 31
algo: bwa-mem
license: sentieon:klib=31
reads: 133396432
overall: 70043910144 mem 23105.370 user 861.001 sys 804.923 real
[main] Version: 0.7.17-r1188
[main] CMD: /opt/conda/share/sentieon-202308.03-3/libexec/bwa mem -K 100000000 -Y -R @RG\tID:A23MHWWLT4.1136_4GR-T1-TDNA-1_A23MHWWLT4_1.L004\tPU:L004\tSM:1136_4GR-T1-TDNA-1_A23MHWWLT4_1\tLB:1136_4GR-T1-TDNA-1_A23MHWWLT4_1\tDS:s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta\tPL:ILLUMINA -t 31 ./BWAIndex/Homo_sapiens_assembly38.fasta.64 1136_4GR-T1-TDNA-1_A23MHWWLT4_1_R1.fastq.gz 1136_4GR-T1-TDNA-1_A23MHWWLT4_1_R2.fastq.gz
[main] Real time: 804.965 sec; CPU: 23966.375 sec
sorting block 125, #reads = 76963 mem = 38459840 peak = 1203912704
uniq header count 1
merging 126 blocks
sw version: sentieon-genomics-202308.03
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000c06f2
  features: bfebfbff 7ffefbff
  extended: f3bfb7ef fb417ffe
  amd bits: 2c100800 00000121
     brand: INTEL(R) XEON(R) PLATINUM 8559C
threads: 31 max 192
algo: util-sort
license: sentieon:util=1
output file size: 7684356412
output reads: 134513737
bam_mem_sort: 126 calls 76.743 user 2.067 sys 79.225 real
bam_write: 126 calls 53.292 user 4.061 sys 68.631 real
execute: 1 calls 41.883 user 2.916 sys 860.064 real
merge_files: 1 calls 41.846 user 2.864 sys 55.053 real
parse_chunk: 2002 calls 109.216 user 29.187 sys 142.625 real
read_chunk: 5414 calls 66.896 user 49.130 sys 726.985 real
sort_block: 1 calls 49.580 user 48.599 sys 702.151 real
write_chunk: 3410 calls 41.457 user 2.523 sys 53.944 real
overall: 3455021056 mem 2180.884 user 107.436 sys 860.098 real
ls: cannot access '*.cram': No such file or directory