This software is licensed to bgold@natera.com by Sentieon Inc.
cmdline: /opt/conda/share/sentieon-202308.03-3/libexec/util sort -r Homo_sapiens_assembly38.fasta -t 31 -o 1029_HTI-T1-TDNA-1_A23MHWWLT4_1.bam --sam2bam -
This software is licensed to bgold@natera.com by Sentieon Inc.
version: sentieon-genomics-202308.03
[M::bwa_idx_load_from_disk] read 3171 ALT contigs
[M::main_mem] bwa index loaded in 2001.872 CPU sec, 79.120 real sec
[M::process] read 700200 sequences (100000237 bp) in 1.343 CPU sec, 1.349 real sec...
[M::process] read 700046 sequences (100000269 bp) in 1.519 CPU sec, 1.523 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 282418, 11, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (279, 360, 1487)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3903)
[M::mem_pestat] mean and std.dev: (870.40, 979.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5111)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 227, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 672)
[M::mem_pestat] mean and std.dev: (250.92, 121.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 844)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (761, 1098, 1593)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3257)
[M::mem_pestat] mean and std.dev: (1189.36, 767.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4259)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (294, 405, 769)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1719)
[M::mem_pestat] mean and std.dev: (387.18, 186.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2194)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698870 sequences (100000225 bp) in 1.429 CPU sec, 1.423 real sec...
[M::process] read 698434 sequences (100000221 bp) in 1.490 CPU sec, 1.492 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 282639, 20, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 581, 704)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1676)
[M::mem_pestat] mean and std.dev: (400.10, 232.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2162)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 229, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 681)
[M::mem_pestat] mean and std.dev: (253.01, 122.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 856)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 626, 1563)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4363)
[M::mem_pestat] mean and std.dev: (772.35, 612.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5763)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 332, 656)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1548)
[M::mem_pestat] mean and std.dev: (381.14, 298.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1994)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700200 reads in 194.909 CPU sec, 6.153 real sec
[M::mem_process_seqs] Processed 700046 reads in 128.800 CPU sec, 4.110 real sec
sorting block 0, #reads = 1073208 mem = 536881233 peak = 590692352
[M::process] read 698174 sequences (100000265 bp) in 1.934 CPU sec, 2.045 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 282332, 24, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (248, 370, 786)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1862)
[M::mem_pestat] mean and std.dev: (512.16, 412.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2400)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 234, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 696)
[M::mem_pestat] mean and std.dev: (258.36, 126.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 875)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (33, 548, 2406)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7152)
[M::mem_pestat] mean and std.dev: (1192.50, 1506.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9525)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 347, 596)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1408)
[M::mem_pestat] mean and std.dev: (368.98, 214.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1814)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697608 sequences (100000154 bp) in 1.709 CPU sec, 1.719 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 282711, 24, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (119, 202, 356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 830)
[M::mem_pestat] mean and std.dev: (191.22, 87.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1067)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 232, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 689)
[M::mem_pestat] mean and std.dev: (256.08, 124.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 866)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (433, 877, 1247)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2875)
[M::mem_pestat] mean and std.dev: (795.50, 488.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3689)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 258, 448)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 910)
[M::mem_pestat] mean and std.dev: (282.71, 140.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1141)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698434 reads in 184.573 CPU sec, 5.916 real sec
[M::mem_process_seqs] Processed 698870 reads in 207.231 CPU sec, 6.656 real sec
sorting block 1, #reads = 1073809 mem = 536879622 peak = 747978752
[M::process] read 697646 sequences (100000050 bp) in 2.195 CPU sec, 2.290 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 282596, 8, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 535, 1089)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2835)
[M::mem_pestat] mean and std.dev: (630.90, 471.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3708)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 235, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 699)
[M::mem_pestat] mean and std.dev: (259.03, 126.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 879)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 262, 406)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 852)
[M::mem_pestat] mean and std.dev: (273.73, 165.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1075)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 697134 sequences (100000145 bp) in 1.660 CPU sec, 1.655 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 281745, 17, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (245, 251, 712)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1646)
[M::mem_pestat] mean and std.dev: (412.32, 256.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2113)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 236, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 703)
[M::mem_pestat] mean and std.dev: (260.78, 127.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 884)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 622, 1668)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4684)
[M::mem_pestat] mean and std.dev: (949.65, 845.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6192)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 523, 1097)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2931)
[M::mem_pestat] mean and std.dev: (739.37, 645.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3848)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698174 reads in 181.905 CPU sec, 5.773 real sec
sorting block 2, #reads = 1073967 mem = 536883178 peak = 770809856
[M::mem_process_seqs] Processed 697608 reads in 202.514 CPU sec, 6.447 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 282046, 19, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 711, 1827)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5163)
[M::mem_pestat] mean and std.dev: (1145.56, 1383.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6831)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 237, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 706)
[M::mem_pestat] mean and std.dev: (261.11, 127.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 888)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (243, 502, 739)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1731)
[M::mem_pestat] mean and std.dev: (416.06, 282.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2227)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 287, 1047)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2745)
[M::mem_pestat] mean and std.dev: (531.25, 565.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3594)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696726 sequences (100000073 bp) in 2.392 CPU sec, 2.520 real sec...
[M::process] read 696282 sequences (100000095 bp) in 1.750 CPU sec, 1.746 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 281971, 34, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 275, 737)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1825)
[M::mem_pestat] mean and std.dev: (433.02, 394.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2369)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 238, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 710)
[M::mem_pestat] mean and std.dev: (262.01, 127.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 893)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (622, 1536, 2637)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6667)
[M::mem_pestat] mean and std.dev: (1349.55, 940.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8682)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (285, 863, 2407)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6651)
[M::mem_pestat] mean and std.dev: (1607.86, 1625.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8773)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697646 reads in 182.459 CPU sec, 5.795 real sec
sorting block 3, #reads = 1074534 mem = 536879002 peak = 785379328
[M::mem_process_seqs] Processed 697134 reads in 122.486 CPU sec, 3.908 real sec
sorting block 4, #reads = 1073302 mem = 536880338 peak = 875839488
[M::process] read 696216 sequences (100000053 bp) in 1.944 CPU sec, 2.065 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 282159, 33, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 292, 497)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1189)
[M::mem_pestat] mean and std.dev: (301.10, 185.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1535)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 239, 345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 711)
[M::mem_pestat] mean and std.dev: (263.37, 128.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 894)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (233, 750, 2151)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5987)
[M::mem_pestat] mean and std.dev: (1503.97, 1652.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8113)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (309, 353, 555)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1047)
[M::mem_pestat] mean and std.dev: (427.72, 231.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1352)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697070 sequences (100000208 bp) in 1.280 CPU sec, 1.279 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 281537, 16, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (241, 330, 745)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1753)
[M::mem_pestat] mean and std.dev: (457.10, 391.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2257)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 240, 348)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 720)
[M::mem_pestat] mean and std.dev: (264.80, 129.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 906)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (480, 871, 3666)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10038)
[M::mem_pestat] mean and std.dev: (1739.38, 1786.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13224)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (314, 557, 835)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1877)
[M::mem_pestat] mean and std.dev: (463.04, 227.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2398)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 281509, 31, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 373, 1314)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3506)
[M::mem_pestat] mean and std.dev: (746.34, 690.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4602)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 241, 350)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 726)
[M::mem_pestat] mean and std.dev: (265.92, 130.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 914)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (543, 1943, 2144)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5346)
[M::mem_pestat] mean and std.dev: (1572.03, 1225.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6947)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (262, 607, 1109)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2803)
[M::mem_pestat] mean and std.dev: (792.33, 787.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3942)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696726 reads in 263.969 CPU sec, 8.501 real sec
[M::mem_process_seqs] Processed 696282 reads in 201.789 CPU sec, 6.530 real sec
[M::mem_process_seqs] Processed 696216 reads in 223.294 CPU sec, 7.233 real sec
sorting block 5, #reads = 1074657 mem = 536880210 peak = 875839488
[M::process] read 697724 sequences (100000073 bp) in 2.270 CPU sec, 2.427 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 282247, 24, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (229, 303, 1145)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2977)
[M::mem_pestat] mean and std.dev: (574.06, 583.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3893)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 238, 347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 719)
[M::mem_pestat] mean and std.dev: (263.74, 129.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 905)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 482, 907)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2425)
[M::mem_pestat] mean and std.dev: (500.48, 458.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3184)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 264, 534)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1296)
[M::mem_pestat] mean and std.dev: (279.13, 179.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1677)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 6, #reads = 1074054 mem = 536878150 peak = 875839488
[M::process] read 696960 sequences (100000151 bp) in 2.289 CPU sec, 2.414 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 282354, 14, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 251, 823)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2127)
[M::mem_pestat] mean and std.dev: (358.45, 281.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2779)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 235, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 706)
[M::mem_pestat] mean and std.dev: (260.78, 128.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 888)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (295, 1549, 1549)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4057)
[M::mem_pestat] mean and std.dev: (772.27, 614.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5311)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 577, 1287)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3437)
[M::mem_pestat] mean and std.dev: (682.81, 582.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4512)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697022 sequences (100000226 bp) in 1.760 CPU sec, 1.756 real sec...
[M::mem_process_seqs] Processed 697070 reads in 192.875 CPU sec, 6.138 real sec
[M::mem_process_seqs] Processed 697724 reads in 129.564 CPU sec, 4.273 real sec
sorting block 7, #reads = 1074433 mem = 536880802 peak = 875839488
[M::process] read 696792 sequences (100000224 bp) in 2.380 CPU sec, 2.520 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 281780, 28, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (141, 294, 678)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1752)
[M::mem_pestat] mean and std.dev: (329.41, 262.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2289)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 238, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 710)
[M::mem_pestat] mean and std.dev: (262.68, 128.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 893)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1143, 1356, 2454)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5076)
[M::mem_pestat] mean and std.dev: (1536.11, 857.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6387)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 293, 788)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2042)
[M::mem_pestat] mean and std.dev: (489.80, 444.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2669)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696656 sequences (100000041 bp) in 1.838 CPU sec, 1.839 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 281430, 30, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 364, 1524)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4168)
[M::mem_pestat] mean and std.dev: (786.00, 780.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5490)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 238, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 710)
[M::mem_pestat] mean and std.dev: (262.60, 128.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 893)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 982, 1622)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4498)
[M::mem_pestat] mean and std.dev: (1183.03, 1108.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5936)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 345, 1039)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2773)
[M::mem_pestat] mean and std.dev: (658.63, 637.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3640)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 281663, 15, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (237, 316, 652)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1482)
[M::mem_pestat] mean and std.dev: (415.07, 294.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1897)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 237, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 710)
[M::mem_pestat] mean and std.dev: (262.28, 128.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 893)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (262, 503, 1594)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4258)
[M::mem_pestat] mean and std.dev: (685.69, 787.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5590)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (266, 480, 1922)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5234)
[M::mem_pestat] mean and std.dev: (945.69, 871.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6890)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696960 reads in 277.503 CPU sec, 9.058 real sec
[M::mem_process_seqs] Processed 696792 reads in 207.362 CPU sec, 6.667 real sec
sorting block 8, #reads = 1074597 mem = 536880736 peak = 875839488
[M::mem_process_seqs] Processed 697022 reads in 228.787 CPU sec, 7.379 real sec
sorting block 9, #reads = 1074292 mem = 536885638 peak = 875839488
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 281706, 9, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 382, 2623)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7465)
[M::mem_pestat] mean and std.dev: (1209.74, 1355.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9886)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 239, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 708)
[M::mem_pestat] mean and std.dev: (262.86, 127.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 890)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 476, 1284)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3488)
[M::mem_pestat] mean and std.dev: (694.08, 672.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4590)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 696434 sequences (100000096 bp) in 3.042 CPU sec, 3.265 real sec...
[M::process] read 695962 sequences (100000105 bp) in 2.082 CPU sec, 2.151 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 281385, 23, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 330, 1467)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4047)
[M::mem_pestat] mean and std.dev: (702.84, 744.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5337)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 238, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 702)
[M::mem_pestat] mean and std.dev: (261.91, 127.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 882)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (278, 580, 1276)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3272)
[M::mem_pestat] mean and std.dev: (718.90, 618.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4270)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 268, 673)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1681)
[M::mem_pestat] mean and std.dev: (392.04, 310.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2185)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695824 sequences (100000062 bp) in 1.780 CPU sec, 1.785 real sec...
[M::mem_process_seqs] Processed 696434 reads in 112.293 CPU sec, 3.534 real sec
sorting block 10, #reads = 1073921 mem = 536880212 peak = 875839488
[M::mem_process_seqs] Processed 696656 reads in 252.414 CPU sec, 8.136 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 281646, 34, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 367, 600)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1374)
[M::mem_pestat] mean and std.dev: (387.05, 267.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1761)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 240, 345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 709)
[M::mem_pestat] mean and std.dev: (263.70, 127.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 891)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (305, 646, 1032)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2486)
[M::mem_pestat] mean and std.dev: (621.88, 406.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3213)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 355, 663)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1539)
[M::mem_pestat] mean and std.dev: (457.54, 333.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1977)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695620 sequences (100000200 bp) in 2.129 CPU sec, 2.482 real sec...
[M::process] read 696090 sequences (100000091 bp) in 1.390 CPU sec, 1.392 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 281444, 30, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (237, 389, 1217)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3177)
[M::mem_pestat] mean and std.dev: (624.53, 538.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4157)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 240, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 703)
[M::mem_pestat] mean and std.dev: (262.63, 126.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 883)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1001, 1362, 2029)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4085)
[M::mem_pestat] mean and std.dev: (1202.54, 636.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5113)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 302, 1217)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3259)
[M::mem_pestat] mean and std.dev: (580.15, 634.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4280)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695962 reads in 217.526 CPU sec, 6.937 real sec
sorting block 11, #reads = 1074748 mem = 536878329 peak = 875839488
[M::mem_process_seqs] Processed 695824 reads in 128.671 CPU sec, 4.151 real sec
sorting block 12, #reads = 1071337 mem = 536882682 peak = 875839488
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 281129, 16, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 347, 871)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2231)
[M::mem_pestat] mean and std.dev: (482.74, 355.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2911)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 240, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 700)
[M::mem_pestat] mean and std.dev: (262.64, 125.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 879)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (296, 399, 1318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3362)
[M::mem_pestat] mean and std.dev: (861.25, 853.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4384)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 337, 905)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2355)
[M::mem_pestat] mean and std.dev: (529.93, 493.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3080)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698344 sequences (100000273 bp) in 2.377 CPU sec, 2.482 real sec...
[M::process] read 696024 sequences (100000257 bp) in 1.880 CPU sec, 1.882 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 281338, 30, 23)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (141, 262, 759)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1995)
[M::mem_pestat] mean and std.dev: (282.28, 217.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2613)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 238, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 691)
[M::mem_pestat] mean and std.dev: (260.38, 124.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 867)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (308, 575, 4127)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 11765)
[M::mem_pestat] mean and std.dev: (1860.43, 2132.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 15584)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 434, 1678)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4598)
[M::mem_pestat] mean and std.dev: (981.22, 989.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6058)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695620 reads in 197.219 CPU sec, 6.343 real sec
[M::mem_process_seqs] Processed 696090 reads in 134.632 CPU sec, 4.315 real sec
sorting block 13, #reads = 1071988 mem = 536880516 peak = 875839488
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 281374, 24, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 527, 1325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3579)
[M::mem_pestat] mean and std.dev: (788.83, 761.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4706)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 231, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 669)
[M::mem_pestat] mean and std.dev: (253.06, 119.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 839)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (294, 426, 875)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2037)
[M::mem_pestat] mean and std.dev: (528.43, 420.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2618)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 397, 652)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1556)
[M::mem_pestat] mean and std.dev: (390.68, 314.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2008)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695760 sequences (100000279 bp) in 2.669 CPU sec, 2.849 real sec...
[M::process] read 695584 sequences (100000089 bp) in 1.442 CPU sec, 1.443 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 281146, 31, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (276, 391, 1299)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3345)
[M::mem_pestat] mean and std.dev: (651.54, 528.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4368)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 238, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 694)
[M::mem_pestat] mean and std.dev: (260.50, 124.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 871)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (315, 623, 1959)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5247)
[M::mem_pestat] mean and std.dev: (1085.62, 1290.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6891)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (237, 318, 1067)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2727)
[M::mem_pestat] mean and std.dev: (466.38, 522.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3557)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698344 reads in 214.169 CPU sec, 6.850 real sec
[M::mem_process_seqs] Processed 696024 reads in 133.964 CPU sec, 4.298 real sec
sorting block 14, #reads = 1065591 mem = 536885025 peak = 875839488
[M::process] read 695776 sequences (100000029 bp) in 2.539 CPU sec, 2.704 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 281054, 23, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 229, 1323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3627)
[M::mem_pestat] mean and std.dev: (649.30, 645.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4779)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 238, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 693)
[M::mem_pestat] mean and std.dev: (260.50, 124.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 870)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (548, 619, 4350)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 11954)
[M::mem_pestat] mean and std.dev: (2054.00, 2338.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 15756)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 342, 754)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1832)
[M::mem_pestat] mean and std.dev: (485.89, 403.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2371)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695018 sequences (100000116 bp) in 1.897 CPU sec, 1.898 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 281339, 26, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 275, 730)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1830)
[M::mem_pestat] mean and std.dev: (431.13, 333.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2380)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 238, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 688)
[M::mem_pestat] mean and std.dev: (260.00, 123.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 863)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (236, 254, 926)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2306)
[M::mem_pestat] mean and std.dev: (521.12, 512.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2996)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (292, 366, 600)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1216)
[M::mem_pestat] mean and std.dev: (372.97, 206.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1524)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695760 reads in 203.856 CPU sec, 6.786 real sec
sorting block 15, #reads = 1072831 mem = 536879817 peak = 875839488
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 281622, 16, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 477, 853)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2121)
[M::mem_pestat] mean and std.dev: (467.20, 315.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2755)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 238, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 691)
[M::mem_pestat] mean and std.dev: (260.41, 124.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 867)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (516, 1165, 2886)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7626)
[M::mem_pestat] mean and std.dev: (1454.33, 1217.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9996)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 333, 1317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3629)
[M::mem_pestat] mean and std.dev: (559.44, 665.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4785)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694894 sequences (100000097 bp) in 2.084 CPU sec, 2.087 real sec...
[M::mem_process_seqs] Processed 695584 reads in 206.933 CPU sec, 6.574 real sec
[M::mem_process_seqs] Processed 695776 reads in 228.389 CPU sec, 7.524 real sec
sorting block 16, #reads = 1071829 mem = 536880636 peak = 875839488
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 281061, 28, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 416, 1001)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2603)
[M::mem_pestat] mean and std.dev: (544.69, 453.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3404)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 239, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 692)
[M::mem_pestat] mean and std.dev: (261.18, 124.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 868)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (384, 1057, 1385)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3387)
[M::mem_pestat] mean and std.dev: (726.50, 466.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4388)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (245, 352, 885)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2165)
[M::mem_pestat] mean and std.dev: (533.06, 452.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2805)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694880 sequences (100000202 bp) in 2.949 CPU sec, 3.158 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 281242, 28, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (134, 265, 550)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1382)
[M::mem_pestat] mean and std.dev: (344.06, 277.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1798)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 239, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 692)
[M::mem_pestat] mean and std.dev: (261.53, 124.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 868)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (82, 555, 1503)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4345)
[M::mem_pestat] mean and std.dev: (699.00, 659.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5766)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (237, 335, 689)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1593)
[M::mem_pestat] mean and std.dev: (436.41, 318.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2045)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694834 sequences (100000157 bp) in 1.890 CPU sec, 1.885 real sec...
[M::mem_process_seqs] Processed 695018 reads in 190.038 CPU sec, 6.289 real sec
sorting block 17, #reads = 1072310 mem = 536882968 peak = 875839488
[M::mem_process_seqs] Processed 694894 reads in 123.960 CPU sec, 4.042 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 281179, 29, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 384, 1740)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4790)
[M::mem_pestat] mean and std.dev: (1076.52, 1366.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6541)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 241, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 701)
[M::mem_pestat] mean and std.dev: (262.99, 125.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 880)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 661, 1873)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5281)
[M::mem_pestat] mean and std.dev: (1089.62, 1249.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6985)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 344, 527)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1241)
[M::mem_pestat] mean and std.dev: (323.54, 175.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1598)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694634 sequences (100000101 bp) in 2.742 CPU sec, 2.923 real sec...
[M::process] read 694662 sequences (100000167 bp) in 1.428 CPU sec, 1.428 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 280917, 13, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 266, 489)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1161)
[M::mem_pestat] mean and std.dev: (293.86, 183.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1497)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 241, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 695)
[M::mem_pestat] mean and std.dev: (262.38, 124.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 872)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (312, 912, 3260)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9156)
[M::mem_pestat] mean and std.dev: (1305.69, 1284.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12104)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (241, 483, 670)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1528)
[M::mem_pestat] mean and std.dev: (446.58, 259.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1957)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 694880 reads in 193.294 CPU sec, 6.261 real sec
sorting block 18, #reads = 1071001 mem = 536879993 peak = 875839488
[M::mem_process_seqs] Processed 694834 reads in 126.650 CPU sec, 4.038 real sec
sorting block 19, #reads = 1071314 mem = 536883824 peak = 980369408
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 280991, 22, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 366, 1434)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3918)
[M::mem_pestat] mean and std.dev: (492.40, 655.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5160)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 241, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 696)
[M::mem_pestat] mean and std.dev: (262.79, 124.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 873)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (243, 602, 907)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2235)
[M::mem_pestat] mean and std.dev: (551.60, 413.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2899)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 370, 2115)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5913)
[M::mem_pestat] mean and std.dev: (739.24, 973.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7812)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694154 sequences (100000056 bp) in 3.011 CPU sec, 3.257 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 280515, 44, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 518, 787)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2025)
[M::mem_pestat] mean and std.dev: (496.95, 396.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2644)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 242, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 696)
[M::mem_pestat] mean and std.dev: (262.95, 124.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 873)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (305, 629, 972)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2306)
[M::mem_pestat] mean and std.dev: (521.89, 351.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2973)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 469, 1504)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4072)
[M::mem_pestat] mean and std.dev: (719.31, 817.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5356)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697704 sequences (100000088 bp) in 2.001 CPU sec, 2.105 real sec...
[M::mem_process_seqs] Processed 694634 reads in 202.542 CPU sec, 6.493 real sec
[M::process] read 698874 sequences (100000120 bp) in 1.986 CPU sec, 1.987 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 280508, 29, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 473, 757)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1899)
[M::mem_pestat] mean and std.dev: (463.91, 339.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2470)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 243, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 702)
[M::mem_pestat] mean and std.dev: (264.19, 125.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 881)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (381, 811, 2044)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5370)
[M::mem_pestat] mean and std.dev: (962.30, 979.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7033)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 465, 1823)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5175)
[M::mem_pestat] mean and std.dev: (997.35, 1047.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6851)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 694154 reads in 111.754 CPU sec, 3.858 real sec
sorting block 20, #reads = 1071513 mem = 536888534 peak = 980369408
[M::mem_process_seqs] Processed 694662 reads in 292.453 CPU sec, 9.680 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 281965, 34, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 397, 1105)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2949)
[M::mem_pestat] mean and std.dev: (648.89, 730.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3871)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 235, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 688)
[M::mem_pestat] mean and std.dev: (257.43, 123.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 864)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (244, 974, 2417)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6763)
[M::mem_pestat] mean and std.dev: (1698.94, 1677.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8936)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (261, 603, 2292)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6354)
[M::mem_pestat] mean and std.dev: (1303.66, 1779.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8420)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 21, #reads = 1071362 mem = 536879162 peak = 980369408
[M::process] read 698112 sequences (100000249 bp) in 2.815 CPU sec, 3.199 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 282246, 30, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 259, 575)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1317)
[M::mem_pestat] mean and std.dev: (332.30, 237.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1688)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 232, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 689)
[M::mem_pestat] mean and std.dev: (256.25, 124.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 866)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (534, 814, 2945)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7767)
[M::mem_pestat] mean and std.dev: (1645.63, 2007.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10178)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 311, 517)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1101)
[M::mem_pestat] mean and std.dev: (399.48, 246.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1393)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697960 sequences (100000011 bp) in 1.797 CPU sec, 1.798 real sec...
[M::mem_process_seqs] Processed 697704 reads in 233.716 CPU sec, 7.562 real sec
[M::mem_process_seqs] Processed 698874 reads in 138.033 CPU sec, 4.506 real sec
sorting block 22, #reads = 1072141 mem = 536879418 peak = 980369408
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 282106, 39, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (259, 437, 915)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2227)
[M::mem_pestat] mean and std.dev: (490.43, 424.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2883)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 234, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 693)
[M::mem_pestat] mean and std.dev: (257.71, 125.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 871)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 438, 1026)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2730)
[M::mem_pestat] mean and std.dev: (657.03, 649.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3582)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (326, 551, 1177)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2879)
[M::mem_pestat] mean and std.dev: (743.55, 606.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3730)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697564 sequences (100000271 bp) in 2.714 CPU sec, 3.048 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 282074, 19, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 464, 802)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2020)
[M::mem_pestat] mean and std.dev: (484.80, 412.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2629)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 235, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 699)
[M::mem_pestat] mean and std.dev: (258.74, 126.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 879)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 442, 2168)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6184)
[M::mem_pestat] mean and std.dev: (812.59, 1124.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8192)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 520, 1609)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4489)
[M::mem_pestat] mean and std.dev: (866.71, 836.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5929)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696992 sequences (100000000 bp) in 1.991 CPU sec, 1.998 real sec...
[M::mem_process_seqs] Processed 698112 reads in 206.158 CPU sec, 6.767 real sec
[M::mem_process_seqs] Processed 697960 reads in 134.413 CPU sec, 4.309 real sec
sorting block 23, #reads = 1074017 mem = 536877408 peak = 980369408
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 282401, 17, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (139, 371, 553)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1381)
[M::mem_pestat] mean and std.dev: (410.09, 344.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1795)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 237, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 703)
[M::mem_pestat] mean and std.dev: (260.68, 127.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 884)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (116, 825, 1219)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3425)
[M::mem_pestat] mean and std.dev: (720.75, 522.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4528)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 409, 479)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1043)
[M::mem_pestat] mean and std.dev: (363.71, 207.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1325)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697056 sequences (100000216 bp) in 2.545 CPU sec, 2.747 real sec...
[M::process] read 696936 sequences (100000218 bp) in 1.884 CPU sec, 1.891 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 282401, 25, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 323, 780)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1992)
[M::mem_pestat] mean and std.dev: (380.89, 339.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2598)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 237, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 710)
[M::mem_pestat] mean and std.dev: (261.95, 128.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 893)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 843, 1527)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4237)
[M::mem_pestat] mean and std.dev: (834.04, 589.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5592)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 242, 438)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 924)
[M::mem_pestat] mean and std.dev: (291.40, 166.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1167)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697564 reads in 200.861 CPU sec, 6.551 real sec
sorting block 24, #reads = 1075492 mem = 536881370 peak = 980369408
[M::mem_process_seqs] Processed 696992 reads in 134.741 CPU sec, 4.461 real sec
sorting block 25, #reads = 1075355 mem = 536884474 peak = 980369408
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 281500, 21, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 630, 1646)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4608)
[M::mem_pestat] mean and std.dev: (820.96, 717.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6089)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 238, 345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 713)
[M::mem_pestat] mean and std.dev: (262.95, 129.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 897)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (106, 387, 649)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1735)
[M::mem_pestat] mean and std.dev: (414.40, 400.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2278)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 256, 587)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1321)
[M::mem_pestat] mean and std.dev: (397.98, 291.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1688)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696590 sequences (100000299 bp) in 2.517 CPU sec, 2.680 real sec...
[M::process] read 696154 sequences (100000095 bp) in 1.830 CPU sec, 1.830 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 282072, 34, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 387, 852)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2138)
[M::mem_pestat] mean and std.dev: (492.66, 364.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2781)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 238, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 710)
[M::mem_pestat] mean and std.dev: (262.80, 128.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 893)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 918, 1380)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3826)
[M::mem_pestat] mean and std.dev: (799.94, 621.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5049)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 301, 810)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2116)
[M::mem_pestat] mean and std.dev: (396.03, 393.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2769)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697056 reads in 187.083 CPU sec, 6.083 real sec
[M::mem_process_seqs] Processed 696936 reads in 118.646 CPU sec, 3.781 real sec
sorting block 26, #reads = 1074480 mem = 536878968 peak = 980369408
[M::process] read 696020 sequences (100000227 bp) in 2.606 CPU sec, 2.770 real sec...
[M::process] read 695744 sequences (100000102 bp) in 1.770 CPU sec, 1.772 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 281542, 21, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 333, 834)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2098)
[M::mem_pestat] mean and std.dev: (531.20, 475.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2730)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 242, 352)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 730)
[M::mem_pestat] mean and std.dev: (266.91, 130.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 919)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (302, 360, 756)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1664)
[M::mem_pestat] mean and std.dev: (488.80, 315.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2118)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (246, 618, 1204)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3120)
[M::mem_pestat] mean and std.dev: (697.37, 583.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4078)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696154 reads in 101.500 CPU sec, 3.257 real sec
sorting block 27, #reads = 1075191 mem = 536878490 peak = 980369408
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 282035, 8, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (226, 419, 871)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2161)
[M::mem_pestat] mean and std.dev: (553.19, 518.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2806)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 240, 348)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 720)
[M::mem_pestat] mean and std.dev: (265.17, 130.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 906)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (255, 507, 1275)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3315)
[M::mem_pestat] mean and std.dev: (699.17, 554.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4335)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 281861, 27, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 479, 1023)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2679)
[M::mem_pestat] mean and std.dev: (645.80, 589.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3507)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 241, 351)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 727)
[M::mem_pestat] mean and std.dev: (266.87, 131.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 915)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (426, 542, 864)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1740)
[M::mem_pestat] mean and std.dev: (525.08, 309.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2178)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (277, 386, 1152)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2902)
[M::mem_pestat] mean and std.dev: (625.66, 530.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3777)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696846 sequences (100000085 bp) in 2.103 CPU sec, 2.119 real sec...
[M::mem_process_seqs] Processed 696590 reads in 295.222 CPU sec, 9.442 real sec
[M::mem_process_seqs] Processed 696020 reads in 149.652 CPU sec, 4.918 real sec
sorting block 28, #reads = 1073763 mem = 536881214 peak = 980369408
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 281429, 25, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 477, 937)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2477)
[M::mem_pestat] mean and std.dev: (530.13, 404.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3247)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 243, 352)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 730)
[M::mem_pestat] mean and std.dev: (267.57, 131.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 919)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (462, 1044, 4411)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12309)
[M::mem_pestat] mean and std.dev: (2163.12, 1913.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 16258)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (234, 375, 1634)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4434)
[M::mem_pestat] mean and std.dev: (955.40, 1124.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5834)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696930 sequences (100000019 bp) in 2.692 CPU sec, 2.898 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 281478, 41, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 473, 858)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2148)
[M::mem_pestat] mean and std.dev: (591.31, 446.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2793)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 238, 345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 713)
[M::mem_pestat] mean and std.dev: (262.81, 128.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 897)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (585, 1713, 4474)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12252)
[M::mem_pestat] mean and std.dev: (2337.83, 2225.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 16141)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 293, 439)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 911)
[M::mem_pestat] mean and std.dev: (321.95, 168.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1147)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696948 sequences (100000003 bp) in 2.095 CPU sec, 2.104 real sec...
[M::mem_process_seqs] Processed 695744 reads in 207.079 CPU sec, 6.763 real sec
[M::mem_process_seqs] Processed 696846 reads in 138.073 CPU sec, 4.534 real sec
sorting block 29, #reads = 1073260 mem = 536878129 peak = 980369408
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 281643, 43, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 265, 771)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1927)
[M::mem_pestat] mean and std.dev: (404.58, 352.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2505)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 238, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 710)
[M::mem_pestat] mean and std.dev: (262.47, 128.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 893)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (226, 852, 2952)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8404)
[M::mem_pestat] mean and std.dev: (1597.90, 2055.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11130)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 332, 892)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2312)
[M::mem_pestat] mean and std.dev: (506.35, 471.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3022)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696408 sequences (100000009 bp) in 2.585 CPU sec, 2.901 real sec...
[M::process] read 696190 sequences (100000230 bp) in 1.930 CPU sec, 1.930 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 282220, 24, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 368, 1572)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4278)
[M::mem_pestat] mean and std.dev: (763.53, 855.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5631)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 238, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 710)
[M::mem_pestat] mean and std.dev: (262.49, 128.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 893)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (142, 526, 1177)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3247)
[M::mem_pestat] mean and std.dev: (627.65, 586.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4282)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 362, 668)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1610)
[M::mem_pestat] mean and std.dev: (355.29, 237.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2081)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696930 reads in 210.129 CPU sec, 6.845 real sec
sorting block 30, #reads = 1074246 mem = 536878366 peak = 980369408
[M::mem_process_seqs] Processed 696948 reads in 137.950 CPU sec, 4.483 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 281666, 16, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 267, 625)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1529)
[M::mem_pestat] mean and std.dev: (292.64, 182.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1981)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 239, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 708)
[M::mem_pestat] mean and std.dev: (263.18, 128.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 890)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (2, 338, 923)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2765)
[M::mem_pestat] mean and std.dev: (440.20, 459.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3686)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 263, 591)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1387)
[M::mem_pestat] mean and std.dev: (336.62, 257.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1785)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 31, #reads = 1073751 mem = 536879222 peak = 980369408
[M::process] read 696084 sequences (100000300 bp) in 2.827 CPU sec, 3.020 real sec...
[M::process] read 696262 sequences (100000218 bp) in 1.577 CPU sec, 1.584 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 281627, 29, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (141, 351, 1414)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3960)
[M::mem_pestat] mean and std.dev: (724.92, 850.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5233)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 239, 345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 709)
[M::mem_pestat] mean and std.dev: (263.49, 128.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 891)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (327, 749, 7803)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 22755)
[M::mem_pestat] mean and std.dev: (2558.52, 3240.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 30231)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 772, 3529)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10143)
[M::mem_pestat] mean and std.dev: (2418.48, 2889.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13975)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696408 reads in 208.849 CPU sec, 6.766 real sec
[M::mem_process_seqs] Processed 696190 reads in 137.455 CPU sec, 4.463 real sec
sorting block 32, #reads = 1073029 mem = 536879441 peak = 980369408
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 281130, 23, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 315, 592)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1410)
[M::mem_pestat] mean and std.dev: (414.06, 302.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1819)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 239, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 708)
[M::mem_pestat] mean and std.dev: (262.62, 127.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 890)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (278, 519, 1651)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4397)
[M::mem_pestat] mean and std.dev: (964.00, 1053.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5770)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 521, 1184)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3122)
[M::mem_pestat] mean and std.dev: (713.85, 638.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4091)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696122 sequences (100000278 bp) in 2.767 CPU sec, 2.949 real sec...
[M::process] read 696618 sequences (100000188 bp) in 1.839 CPU sec, 1.847 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 281069, 38, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 259, 486)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1162)
[M::mem_pestat] mean and std.dev: (297.33, 205.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1500)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 238, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 702)
[M::mem_pestat] mean and std.dev: (261.88, 126.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 882)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (129, 450, 2379)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6879)
[M::mem_pestat] mean and std.dev: (1077.05, 1268.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9129)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 350, 662)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1572)
[M::mem_pestat] mean and std.dev: (345.12, 213.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2027)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696084 reads in 209.652 CPU sec, 6.807 real sec
[M::mem_process_seqs] Processed 696262 reads in 137.697 CPU sec, 4.491 real sec
sorting block 33, #reads = 1072403 mem = 536879027 peak = 980369408
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 281373, 30, 24)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 345, 453)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1031)
[M::mem_pestat] mean and std.dev: (309.32, 170.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1320)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 238, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 699)
[M::mem_pestat] mean and std.dev: (261.10, 125.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 878)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (328, 959, 2193)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5923)
[M::mem_pestat] mean and std.dev: (1333.97, 1184.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7788)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 182, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 727)
[M::mem_pestat] mean and std.dev: (209.24, 109.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 920)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696764 sequences (100000273 bp) in 2.805 CPU sec, 2.932 real sec...
[M::process] read 697114 sequences (100000281 bp) in 2.029 CPU sec, 2.039 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 281473, 46, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 311, 1056)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2760)
[M::mem_pestat] mean and std.dev: (545.40, 502.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3612)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 236, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 692)
[M::mem_pestat] mean and std.dev: (259.27, 125.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 869)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (346, 817, 1372)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3424)
[M::mem_pestat] mean and std.dev: (904.26, 711.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4450)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 251, 1349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3717)
[M::mem_pestat] mean and std.dev: (837.33, 944.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4901)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696122 reads in 209.867 CPU sec, 6.807 real sec
[M::mem_process_seqs] Processed 696618 reads in 142.067 CPU sec, 4.548 real sec
sorting block 34, #reads = 1072651 mem = 536879486 peak = 980369408
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 281560, 29, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 273, 407)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 865)
[M::mem_pestat] mean and std.dev: (262.03, 136.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1094)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 236, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 695)
[M::mem_pestat] mean and std.dev: (259.76, 125.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 873)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 987, 1376)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3820)
[M::mem_pestat] mean and std.dev: (946.66, 779.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5042)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 610, 1500)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4042)
[M::mem_pestat] mean and std.dev: (922.48, 921.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5313)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698694 sequences (100000190 bp) in 2.780 CPU sec, 3.010 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 281657, 32, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 288, 1104)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3006)
[M::mem_pestat] mean and std.dev: (736.32, 773.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3957)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 234, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 688)
[M::mem_pestat] mean and std.dev: (257.93, 124.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 864)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (83, 436, 850)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2384)
[M::mem_pestat] mean and std.dev: (484.03, 509.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3151)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 511, 1550)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4238)
[M::mem_pestat] mean and std.dev: (830.08, 932.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5582)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696234 sequences (100000131 bp) in 2.079 CPU sec, 2.191 real sec...
[M::mem_process_seqs] Processed 696764 reads in 212.440 CPU sec, 7.311 real sec
sorting block 35, #reads = 1072174 mem = 536878136 peak = 980369408
[M::mem_process_seqs] Processed 697114 reads in 142.723 CPU sec, 5.155 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 281664, 35, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 300, 704)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1748)
[M::mem_pestat] mean and std.dev: (420.77, 316.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2270)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 232, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 683)
[M::mem_pestat] mean and std.dev: (254.95, 123.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 858)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (357, 536, 2293)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6165)
[M::mem_pestat] mean and std.dev: (1148.59, 1266.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8101)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 440, 819)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2099)
[M::mem_pestat] mean and std.dev: (572.05, 520.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2739)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 36, #reads = 1073261 mem = 536879602 peak = 980369408
[M::process] read 696024 sequences (100000028 bp) in 2.666 CPU sec, 3.024 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 281348, 17, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 358, 1857)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5229)
[M::mem_pestat] mean and std.dev: (1044.46, 1425.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6915)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 238, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 696)
[M::mem_pestat] mean and std.dev: (260.16, 124.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 874)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 326, 947)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2455)
[M::mem_pestat] mean and std.dev: (494.73, 415.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3209)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 537, 1357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3677)
[M::mem_pestat] mean and std.dev: (741.70, 666.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4837)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696072 sequences (100000008 bp) in 2.064 CPU sec, 2.134 real sec...
[M::mem_process_seqs] Processed 698694 reads in 231.406 CPU sec, 7.960 real sec
[M::mem_process_seqs] Processed 696234 reads in 144.954 CPU sec, 4.809 real sec
sorting block 37, #reads = 1067457 mem = 536884186 peak = 980369408
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 281226, 32, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 393, 1355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3721)
[M::mem_pestat] mean and std.dev: (690.93, 746.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4904)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 237, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 696)
[M::mem_pestat] mean and std.dev: (260.66, 125.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 874)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (410, 617, 1512)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3716)
[M::mem_pestat] mean and std.dev: (677.04, 584.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4818)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 296, 994)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2600)
[M::mem_pestat] mean and std.dev: (484.75, 460.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3403)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695552 sequences (100000273 bp) in 2.548 CPU sec, 2.986 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 281259, 31, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 450, 1089)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2841)
[M::mem_pestat] mean and std.dev: (625.74, 599.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3717)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 238, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 696)
[M::mem_pestat] mean and std.dev: (260.68, 125.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 874)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 383, 1179)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3179)
[M::mem_pestat] mean and std.dev: (396.50, 392.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4179)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (231, 311, 612)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1374)
[M::mem_pestat] mean and std.dev: (397.54, 273.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1755)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695386 sequences (100000221 bp) in 1.922 CPU sec, 2.074 real sec...
[M::mem_process_seqs] Processed 696024 reads in 215.919 CPU sec, 7.494 real sec
[M::mem_process_seqs] Processed 696072 reads in 140.914 CPU sec, 4.781 real sec
sorting block 38, #reads = 1072027 mem = 536878272 peak = 980369408
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 281177, 27, 24)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 543, 912)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2366)
[M::mem_pestat] mean and std.dev: (531.06, 375.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3093)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 239, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 697)
[M::mem_pestat] mean and std.dev: (261.91, 125.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 875)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 433, 2099)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5953)
[M::mem_pestat] mean and std.dev: (966.35, 965.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7880)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 370, 3325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9653)
[M::mem_pestat] mean and std.dev: (1316.50, 1677.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12817)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695078 sequences (100000023 bp) in 2.466 CPU sec, 2.923 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 281054, 17, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 285, 680)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1646)
[M::mem_pestat] mean and std.dev: (357.89, 224.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2129)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 239, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 694)
[M::mem_pestat] mean and std.dev: (261.25, 124.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 871)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (360, 982, 2223)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5949)
[M::mem_pestat] mean and std.dev: (1506.24, 1540.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7812)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (256, 541, 2048)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5632)
[M::mem_pestat] mean and std.dev: (1084.25, 1111.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7424)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695552 reads in 210.374 CPU sec, 7.299 real sec
[M::process] read 694948 sequences (100000125 bp) in 2.123 CPU sec, 2.163 real sec...
sorting block 39, #reads = 1072658 mem = 536880938 peak = 980369408
[M::mem_process_seqs] Processed 695386 reads in 141.929 CPU sec, 4.880 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 280734, 29, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 298, 544)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1274)
[M::mem_pestat] mean and std.dev: (360.24, 239.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1639)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 241, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 695)
[M::mem_pestat] mean and std.dev: (262.02, 124.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 872)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (398, 553, 1908)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4928)
[M::mem_pestat] mean and std.dev: (982.25, 945.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6438)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 320, 709)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1693)
[M::mem_pestat] mean and std.dev: (345.90, 210.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2185)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 40, #reads = 1071281 mem = 536879386 peak = 980369408
[M::process] read 694756 sequences (100000190 bp) in 2.550 CPU sec, 2.916 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 281205, 24, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 268, 530)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1188)
[M::mem_pestat] mean and std.dev: (309.64, 179.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1517)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 241, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 701)
[M::mem_pestat] mean and std.dev: (262.78, 125.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 880)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (456, 1391, 3495)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9573)
[M::mem_pestat] mean and std.dev: (1724.88, 1437.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12612)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 294, 925)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2455)
[M::mem_pestat] mean and std.dev: (389.73, 391.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3220)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695078 reads in 211.306 CPU sec, 7.547 real sec
[M::process] read 694784 sequences (100000170 bp) in 2.202 CPU sec, 2.314 real sec...
[M::mem_process_seqs] Processed 694948 reads in 149.727 CPU sec, 5.076 real sec
sorting block 41, #reads = 1070824 mem = 536878865 peak = 980369408
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 281320, 33, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (234, 400, 947)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2373)
[M::mem_pestat] mean and std.dev: (540.11, 469.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3086)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 241, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 701)
[M::mem_pestat] mean and std.dev: (263.26, 125.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 880)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (123, 259, 1047)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2895)
[M::mem_pestat] mean and std.dev: (557.03, 518.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3819)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 432, 602)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1454)
[M::mem_pestat] mean and std.dev: (381.94, 258.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1880)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694616 sequences (100000159 bp) in 2.670 CPU sec, 3.171 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 281364, 36, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 240, 1043)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2781)
[M::mem_pestat] mean and std.dev: (469.58, 485.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3650)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 242, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 704)
[M::mem_pestat] mean and std.dev: (264.20, 126.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 884)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 323, 1072)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2896)
[M::mem_pestat] mean and std.dev: (519.27, 577.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3808)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 399, 1185)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3103)
[M::mem_pestat] mean and std.dev: (738.11, 718.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4062)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 694756 reads in 209.857 CPU sec, 6.943 real sec
[M::process] read 697590 sequences (100000199 bp) in 2.179 CPU sec, 2.268 real sec...
[M::mem_process_seqs] Processed 694784 reads in 142.327 CPU sec, 5.014 real sec
sorting block 42, #reads = 1071587 mem = 536881738 peak = 984514560
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 281412, 25, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (259, 471, 887)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2143)
[M::mem_pestat] mean and std.dev: (556.36, 435.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2771)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 242, 347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 711)
[M::mem_pestat] mean and std.dev: (265.49, 127.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 893)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (403, 842, 1104)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2506)
[M::mem_pestat] mean and std.dev: (764.87, 475.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3207)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 220, 390)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 846)
[M::mem_pestat] mean and std.dev: (235.59, 123.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1074)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699702 sequences (100000200 bp) in 2.793 CPU sec, 3.177 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 281537, 27, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (230, 573, 1430)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3830)
[M::mem_pestat] mean and std.dev: (797.15, 771.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5030)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 235, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 697)
[M::mem_pestat] mean and std.dev: (258.98, 125.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 876)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 1123, 1248)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3406)
[M::mem_pestat] mean and std.dev: (875.00, 712.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4485)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (234, 341, 476)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 960)
[M::mem_pestat] mean and std.dev: (287.37, 111.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1202)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698586 sequences (100000194 bp) in 1.952 CPU sec, 1.958 real sec...
[M::mem_process_seqs] Processed 694616 reads in 208.860 CPU sec, 7.055 real sec
sorting block 43, #reads = 1071835 mem = 536886851 peak = 984514560
[M::mem_process_seqs] Processed 697590 reads in 138.881 CPU sec, 4.447 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23, 282164, 17, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 469, 1010)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2670)
[M::mem_pestat] mean and std.dev: (647.43, 537.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3500)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 229, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 682)
[M::mem_pestat] mean and std.dev: (253.75, 123.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 857)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (29, 325, 654)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1904)
[M::mem_pestat] mean and std.dev: (298.27, 303.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2529)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 299, 865)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2235)
[M::mem_pestat] mean and std.dev: (484.86, 428.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2920)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 44, #reads = 1071141 mem = 536882259 peak = 1014366208
[M::process] read 697746 sequences (100000221 bp) in 2.850 CPU sec, 3.038 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 281951, 20, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (137, 353, 1094)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3008)
[M::mem_pestat] mean and std.dev: (492.45, 473.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3965)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 232, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 692)
[M::mem_pestat] mean and std.dev: (256.76, 125.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 870)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 908, 1041)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2679)
[M::mem_pestat] mean and std.dev: (691.06, 545.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3498)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 557, 819)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2011)
[M::mem_pestat] mean and std.dev: (504.03, 313.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2607)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697380 sequences (100000227 bp) in 2.007 CPU sec, 2.024 real sec...
[M::mem_process_seqs] Processed 699702 reads in 197.235 CPU sec, 6.326 real sec
[M::mem_process_seqs] Processed 698586 reads in 131.611 CPU sec, 4.507 real sec
sorting block 45, #reads = 1072879 mem = 536881488 peak = 1014366208
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 282195, 29, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 252, 740)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1868)
[M::mem_pestat] mean and std.dev: (396.54, 361.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2432)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 234, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 697)
[M::mem_pestat] mean and std.dev: (259.24, 126.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 876)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (97, 448, 651)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1759)
[M::mem_pestat] mean and std.dev: (385.89, 387.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2313)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 355, 686)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1620)
[M::mem_pestat] mean and std.dev: (435.63, 298.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2087)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696820 sequences (100000027 bp) in 2.898 CPU sec, 3.251 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 281585, 34, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (259, 428, 511)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1015)
[M::mem_pestat] mean and std.dev: (385.32, 209.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1267)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 236, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 700)
[M::mem_pestat] mean and std.dev: (259.80, 126.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 880)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (540, 925, 1062)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2106)
[M::mem_pestat] mean and std.dev: (733.75, 473.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2629)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 395, 1215)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3335)
[M::mem_pestat] mean and std.dev: (715.00, 774.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4395)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696646 sequences (100000193 bp) in 1.911 CPU sec, 1.916 real sec...
[M::mem_process_seqs] Processed 697746 reads in 207.079 CPU sec, 6.977 real sec
[M::mem_process_seqs] Processed 697380 reads in 138.466 CPU sec, 4.418 real sec
sorting block 46, #reads = 1074143 mem = 536879028 peak = 1014366208
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 281980, 24, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 247, 1566)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4308)
[M::mem_pestat] mean and std.dev: (748.85, 829.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5679)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 239, 345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 713)
[M::mem_pestat] mean and std.dev: (262.98, 128.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 897)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 807, 2912)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8310)
[M::mem_pestat] mean and std.dev: (1297.91, 1306.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11009)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (359, 460, 662)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1268)
[M::mem_pestat] mean and std.dev: (488.88, 243.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1571)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696298 sequences (100000216 bp) in 2.687 CPU sec, 2.875 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (22, 282019, 21, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 292, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 614)
[M::mem_pestat] mean and std.dev: (254.67, 112.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 758)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 239, 346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 716)
[M::mem_pestat] mean and std.dev: (263.61, 128.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 901)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (134, 1488, 2346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6770)
[M::mem_pestat] mean and std.dev: (1278.95, 1012.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8982)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (306, 439, 711)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1521)
[M::mem_pestat] mean and std.dev: (481.49, 332.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1926)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695712 sequences (100000222 bp) in 2.000 CPU sec, 2.009 real sec...
[M::mem_process_seqs] Processed 696820 reads in 197.653 CPU sec, 6.312 real sec
sorting block 47, #reads = 1073700 mem = 536877819 peak = 1014366208
[M::mem_process_seqs] Processed 696646 reads in 133.771 CPU sec, 4.544 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 281873, 33, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (227, 382, 2862)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8132)
[M::mem_pestat] mean and std.dev: (1418.50, 1708.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10767)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 241, 348)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 720)
[M::mem_pestat] mean and std.dev: (265.46, 130.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 906)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 633, 1115)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2897)
[M::mem_pestat] mean and std.dev: (575.14, 490.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3788)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (313, 510, 1634)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4276)
[M::mem_pestat] mean and std.dev: (1012.40, 1058.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5597)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 48, #reads = 1073553 mem = 536883443 peak = 1014366208
[M::process] read 695486 sequences (100000032 bp) in 2.928 CPU sec, 3.109 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 281523, 28, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (244, 311, 751)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1765)
[M::mem_pestat] mean and std.dev: (360.32, 245.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2272)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 242, 350)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 724)
[M::mem_pestat] mean and std.dev: (266.53, 130.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 911)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (330, 988, 3032)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8436)
[M::mem_pestat] mean and std.dev: (1476.32, 1464.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11138)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 399, 606)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1482)
[M::mem_pestat] mean and std.dev: (436.20, 309.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1920)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695452 sequences (100000048 bp) in 1.981 CPU sec, 1.987 real sec...
[M::mem_process_seqs] Processed 696298 reads in 200.227 CPU sec, 6.672 real sec
[M::mem_process_seqs] Processed 695712 reads in 132.930 CPU sec, 4.320 real sec
sorting block 49, #reads = 1074463 mem = 536880437 peak = 1014366208
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 281411, 22, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (275, 396, 861)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2033)
[M::mem_pestat] mean and std.dev: (429.65, 252.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2619)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 243, 352)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 728)
[M::mem_pestat] mean and std.dev: (267.63, 130.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 916)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (294, 717, 1194)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2994)
[M::mem_pestat] mean and std.dev: (844.00, 673.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3894)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 294, 789)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2045)
[M::mem_pestat] mean and std.dev: (417.51, 463.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2673)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695276 sequences (100000038 bp) in 2.800 CPU sec, 2.921 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 281509, 25, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 325, 1369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3645)
[M::mem_pestat] mean and std.dev: (658.18, 894.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4783)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 243, 353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 731)
[M::mem_pestat] mean and std.dev: (268.63, 132.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 920)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (521, 522, 596)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (371, 746)
[M::mem_pestat] mean and std.dev: (518.67, 59.32)
[M::mem_pestat] low and high boundaries for proper pairs: (281, 821)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 708, 1106)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2872)
[M::mem_pestat] mean and std.dev: (790.33, 687.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3755)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696346 sequences (100000088 bp) in 1.860 CPU sec, 1.861 real sec...
[M::mem_process_seqs] Processed 695486 reads in 181.813 CPU sec, 5.887 real sec
[M::mem_process_seqs] Processed 695452 reads in 118.627 CPU sec, 3.854 real sec
sorting block 50, #reads = 1072550 mem = 536878736 peak = 1014366208
[M::process] read 697374 sequences (100000001 bp) in 2.654 CPU sec, 2.770 real sec...
[M::process] read 696272 sequences (100000111 bp) in 1.800 CPU sec, 1.806 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 281853, 16, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 351, 855)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2195)
[M::mem_pestat] mean and std.dev: (347.21, 250.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2865)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 240, 347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 717)
[M::mem_pestat] mean and std.dev: (264.50, 129.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 902)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (796, 1168, 1426)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2686)
[M::mem_pestat] mean and std.dev: (869.64, 476.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3316)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 225, 1541)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4237)
[M::mem_pestat] mean and std.dev: (861.04, 1046.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5585)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696346 reads in 98.709 CPU sec, 3.158 real sec
sorting block 51, #reads = 1073186 mem = 536883158 peak = 1014366208
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 281669, 33, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (146, 283, 640)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1628)
[M::mem_pestat] mean and std.dev: (439.92, 418.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2122)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 244, 355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 737)
[M::mem_pestat] mean and std.dev: (269.62, 132.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 928)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (589, 956, 3223)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8491)
[M::mem_pestat] mean and std.dev: (1645.94, 1474.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11125)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 380, 819)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1999)
[M::mem_pestat] mean and std.dev: (514.88, 433.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2589)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 282289, 14, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (237, 403, 1097)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2817)
[M::mem_pestat] mean and std.dev: (544.00, 409.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3677)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 236, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 703)
[M::mem_pestat] mean and std.dev: (260.76, 128.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 884)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (87, 374, 1009)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2853)
[M::mem_pestat] mean and std.dev: (633.64, 569.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3775)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 254, 304)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 610)
[M::mem_pestat] mean and std.dev: (258.91, 136.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 805)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696126 sequences (100000276 bp) in 2.071 CPU sec, 2.073 real sec...
[M::mem_process_seqs] Processed 695276 reads in 284.757 CPU sec, 9.184 real sec
[M::mem_process_seqs] Processed 697374 reads in 147.365 CPU sec, 4.755 real sec
sorting block 52, #reads = 1074084 mem = 536878638 peak = 1014366208
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 282094, 32, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 267, 470)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1066)
[M::mem_pestat] mean and std.dev: (248.10, 108.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1364)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 239, 345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 711)
[M::mem_pestat] mean and std.dev: (263.49, 128.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 894)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (95, 227, 650)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1760)
[M::mem_pestat] mean and std.dev: (320.00, 316.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2315)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (245, 323, 1232)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3206)
[M::mem_pestat] mean and std.dev: (561.68, 628.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4193)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696236 sequences (100000143 bp) in 2.553 CPU sec, 2.720 real sec...
[M::process] read 695998 sequences (100000034 bp) in 1.890 CPU sec, 1.898 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 281102, 27, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 254, 620)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1556)
[M::mem_pestat] mean and std.dev: (400.02, 355.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2024)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 240, 345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 711)
[M::mem_pestat] mean and std.dev: (263.77, 128.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 894)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (315, 522, 1548)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4014)
[M::mem_pestat] mean and std.dev: (1103.46, 1138.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5658)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 340, 1102)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2872)
[M::mem_pestat] mean and std.dev: (693.44, 789.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3849)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696272 reads in 188.466 CPU sec, 5.994 real sec
sorting block 53, #reads = 1073264 mem = 536885396 peak = 1014366208
[M::mem_process_seqs] Processed 696126 reads in 129.287 CPU sec, 4.407 real sec
[M::process] read 695974 sequences (100000068 bp) in 2.329 CPU sec, 2.493 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 281290, 39, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 301, 1202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3284)
[M::mem_pestat] mean and std.dev: (651.76, 690.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4325)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 238, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 705)
[M::mem_pestat] mean and std.dev: (262.32, 127.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 886)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (344, 483, 630)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1202)
[M::mem_pestat] mean and std.dev: (418.30, 212.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1488)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (247, 343, 574)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1228)
[M::mem_pestat] mean and std.dev: (361.70, 194.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1555)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696236 reads in 104.423 CPU sec, 3.652 real sec
sorting block 54, #reads = 1073130 mem = 536885495 peak = 1014366208
[M::process] read 695876 sequences (100000002 bp) in 2.005 CPU sec, 2.161 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 281500, 29, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 338, 468)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1022)
[M::mem_pestat] mean and std.dev: (344.02, 199.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1299)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 239, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 705)
[M::mem_pestat] mean and std.dev: (262.52, 127.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 886)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (357, 620, 3654)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10248)
[M::mem_pestat] mean and std.dev: (1888.41, 2269.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13545)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (231, 481, 912)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2274)
[M::mem_pestat] mean and std.dev: (506.38, 407.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2955)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696206 sequences (100000072 bp) in 1.910 CPU sec, 1.912 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 281713, 22, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 375, 1091)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2881)
[M::mem_pestat] mean and std.dev: (558.86, 517.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3776)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 239, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 699)
[M::mem_pestat] mean and std.dev: (261.73, 126.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 878)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (253, 442, 1331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3487)
[M::mem_pestat] mean and std.dev: (905.91, 1002.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4915)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 309, 792)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1994)
[M::mem_pestat] mean and std.dev: (442.97, 354.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2595)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695998 reads in 212.723 CPU sec, 6.800 real sec
[M::mem_process_seqs] Processed 695974 reads in 230.632 CPU sec, 7.457 real sec
sorting block 55, #reads = 1073052 mem = 536879403 peak = 1014366208
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 281534, 22, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 428, 974)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2504)
[M::mem_pestat] mean and std.dev: (629.02, 513.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3269)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 238, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 702)
[M::mem_pestat] mean and std.dev: (261.71, 126.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 882)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (20, 239, 1477)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4391)
[M::mem_pestat] mean and std.dev: (694.00, 937.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5848)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 297, 710)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1720)
[M::mem_pestat] mean and std.dev: (366.08, 278.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2225)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695974 sequences (100000153 bp) in 2.730 CPU sec, 2.902 real sec...
[M::process] read 697192 sequences (100000075 bp) in 1.812 CPU sec, 1.815 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 281482, 26, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 493, 1088)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2860)
[M::mem_pestat] mean and std.dev: (590.25, 475.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3746)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 238, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 699)
[M::mem_pestat] mean and std.dev: (261.27, 126.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 878)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (125, 317, 776)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2078)
[M::mem_pestat] mean and std.dev: (376.59, 357.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2729)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 316, 533)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1211)
[M::mem_pestat] mean and std.dev: (349.91, 251.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1550)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695876 reads in 200.355 CPU sec, 6.480 real sec
sorting block 56, #reads = 1073616 mem = 536880411 peak = 1014366208
[M::mem_process_seqs] Processed 696206 reads in 131.718 CPU sec, 4.189 real sec
sorting block 57, #reads = 1071844 mem = 536880998 peak = 1070661632
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 281608, 23, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (256, 421, 924)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2260)
[M::mem_pestat] mean and std.dev: (577.69, 457.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2928)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 238, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 699)
[M::mem_pestat] mean and std.dev: (261.45, 126.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 878)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (93, 212, 993)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2793)
[M::mem_pestat] mean and std.dev: (621.87, 701.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3693)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 380, 747)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1855)
[M::mem_pestat] mean and std.dev: (497.21, 436.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2409)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696336 sequences (100000229 bp) in 2.756 CPU sec, 2.918 real sec...
[M::process] read 696092 sequences (100000154 bp) in 2.021 CPU sec, 2.025 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 281606, 25, 72)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 347, 622)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1530)
[M::mem_pestat] mean and std.dev: (460.18, 409.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2100)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 234, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 688)
[M::mem_pestat] mean and std.dev: (257.75, 124.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 864)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 793, 1826)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5152)
[M::mem_pestat] mean and std.dev: (1121.21, 1154.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6815)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (302, 370, 669)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1403)
[M::mem_pestat] mean and std.dev: (427.56, 238.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1770)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695974 reads in 201.194 CPU sec, 6.509 real sec
[M::mem_process_seqs] Processed 697192 reads in 137.330 CPU sec, 4.376 real sec
sorting block 58, #reads = 1073157 mem = 536881071 peak = 1070661632
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 281279, 29, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 356, 941)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2439)
[M::mem_pestat] mean and std.dev: (665.37, 600.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3188)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 237, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 696)
[M::mem_pestat] mean and std.dev: (260.51, 125.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 874)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (318, 760, 3117)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8715)
[M::mem_pestat] mean and std.dev: (1566.14, 1518.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11514)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 255, 473)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1005)
[M::mem_pestat] mean and std.dev: (295.12, 136.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1271)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695990 sequences (100000150 bp) in 2.847 CPU sec, 3.014 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 280986, 18, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 429, 915)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2379)
[M::mem_pestat] mean and std.dev: (566.96, 507.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3111)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 237, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 696)
[M::mem_pestat] mean and std.dev: (260.77, 125.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 874)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (3, 771, 2109)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6321)
[M::mem_pestat] mean and std.dev: (1176.89, 1493.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8427)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 257, 415)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 855)
[M::mem_pestat] mean and std.dev: (252.12, 95.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1075)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695688 sequences (100000255 bp) in 2.050 CPU sec, 2.056 real sec...
[M::mem_process_seqs] Processed 696336 reads in 198.727 CPU sec, 6.329 real sec
[M::mem_process_seqs] Processed 696092 reads in 133.438 CPU sec, 4.514 real sec
sorting block 59, #reads = 1070728 mem = 536879846 peak = 1070661632
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 281490, 17, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (233, 325, 789)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1901)
[M::mem_pestat] mean and std.dev: (436.85, 329.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2457)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 238, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 702)
[M::mem_pestat] mean and std.dev: (261.67, 126.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 882)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (249, 555, 849)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2049)
[M::mem_pestat] mean and std.dev: (602.82, 442.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2649)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 323, 1037)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2721)
[M::mem_pestat] mean and std.dev: (569.62, 508.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3563)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695716 sequences (100000132 bp) in 2.920 CPU sec, 3.086 real sec...
[M::process] read 695582 sequences (100000261 bp) in 2.004 CPU sec, 2.004 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 281185, 26, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 255, 448)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 996)
[M::mem_pestat] mean and std.dev: (272.38, 148.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1270)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 239, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 705)
[M::mem_pestat] mean and std.dev: (262.72, 127.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 886)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (320, 1190, 1538)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3974)
[M::mem_pestat] mean and std.dev: (1085.69, 872.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5192)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 223, 479)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1063)
[M::mem_pestat] mean and std.dev: (328.93, 243.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1355)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695990 reads in 202.097 CPU sec, 6.711 real sec
sorting block 60, #reads = 1071771 mem = 536882047 peak = 1070661632
[M::mem_process_seqs] Processed 695688 reads in 132.155 CPU sec, 4.304 real sec
sorting block 61, #reads = 1073540 mem = 536879165 peak = 1070661632
[M::process] read 695450 sequences (100000003 bp) in 2.665 CPU sec, 2.836 real sec...
[M::process] read 695028 sequences (100000137 bp) in 1.906 CPU sec, 1.909 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 281227, 33, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 342, 938)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2448)
[M::mem_pestat] mean and std.dev: (505.59, 479.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3203)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 239, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 697)
[M::mem_pestat] mean and std.dev: (261.53, 125.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 875)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (86, 366, 534)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1430)
[M::mem_pestat] mean and std.dev: (362.19, 298.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1878)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 445, 1237)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3275)
[M::mem_pestat] mean and std.dev: (784.95, 805.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4294)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695582 reads in 114.891 CPU sec, 3.647 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 280990, 16, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (244, 413, 998)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2506)
[M::mem_pestat] mean and std.dev: (558.31, 452.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3260)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 238, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 699)
[M::mem_pestat] mean and std.dev: (261.80, 126.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 878)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (386, 2728, 3893)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10907)
[M::mem_pestat] mean and std.dev: (2364.00, 2127.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14414)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 503, 986)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2516)
[M::mem_pestat] mean and std.dev: (476.54, 411.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3281)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (73, 281015, 30, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 352, 1063)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2803)
[M::mem_pestat] mean and std.dev: (483.98, 537.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3673)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 240, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 703)
[M::mem_pestat] mean and std.dev: (262.71, 126.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 883)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (437, 784, 882)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1772)
[M::mem_pestat] mean and std.dev: (734.87, 489.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2693)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 460, 1386)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3784)
[M::mem_pestat] mean and std.dev: (802.64, 791.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4983)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695122 sequences (100000272 bp) in 2.066 CPU sec, 2.074 real sec...
[M::mem_process_seqs] Processed 695716 reads in 309.221 CPU sec, 9.936 real sec
sorting block 62, #reads = 1071627 mem = 536878961 peak = 1070661632
[M::mem_process_seqs] Processed 695450 reads in 154.775 CPU sec, 4.945 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 281013, 29, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 235, 543)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1301)
[M::mem_pestat] mean and std.dev: (386.70, 350.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1788)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 241, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 704)
[M::mem_pestat] mean and std.dev: (263.44, 126.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 884)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (240, 348, 771)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1833)
[M::mem_pestat] mean and std.dev: (441.85, 432.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2364)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 275, 522)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1114)
[M::mem_pestat] mean and std.dev: (363.30, 257.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1410)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 63, #reads = 1072002 mem = 536881015 peak = 1070661632
[M::process] read 695372 sequences (100000196 bp) in 3.036 CPU sec, 3.210 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 280353, 35, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (236, 303, 845)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2063)
[M::mem_pestat] mean and std.dev: (472.29, 483.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2672)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::process] read 694456 sequences (100000294 bp) in 1.909 CPU sec, 1.912 real sec...
[M::mem_pestat] (25, 50, 75) percentile: (163, 240, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 703)
[M::mem_pestat] mean and std.dev: (262.96, 126.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 883)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (482, 825, 2146)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5474)
[M::mem_pestat] mean and std.dev: (1174.42, 1058.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7138)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 290, 721)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1767)
[M::mem_pestat] mean and std.dev: (351.30, 225.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2290)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695028 reads in 200.846 CPU sec, 6.500 real sec
[M::mem_process_seqs] Processed 695122 reads in 136.445 CPU sec, 4.340 real sec
sorting block 64, #reads = 1071233 mem = 536878760 peak = 1070661632
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 281061, 27, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 295, 1172)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3210)
[M::mem_pestat] mean and std.dev: (828.16, 1040.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4990)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 240, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 703)
[M::mem_pestat] mean and std.dev: (263.20, 127.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 883)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (119, 296, 1222)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3428)
[M::mem_pestat] mean and std.dev: (498.00, 528.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4531)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (250, 344, 2829)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7987)
[M::mem_pestat] mean and std.dev: (1336.76, 1714.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10566)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695424 sequences (100000072 bp) in 2.832 CPU sec, 3.012 real sec...
[M::process] read 698766 sequences (100000101 bp) in 1.869 CPU sec, 1.879 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 281076, 23, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (226, 364, 1226)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3226)
[M::mem_pestat] mean and std.dev: (611.18, 724.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4226)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 243, 347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 711)
[M::mem_pestat] mean and std.dev: (265.40, 127.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 893)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (404, 1074, 3136)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8600)
[M::mem_pestat] mean and std.dev: (1567.09, 1685.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11332)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 354, 1114)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2944)
[M::mem_pestat] mean and std.dev: (635.48, 649.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3859)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695372 reads in 196.168 CPU sec, 6.244 real sec
[M::mem_process_seqs] Processed 694456 reads in 131.628 CPU sec, 4.458 real sec
sorting block 65, #reads = 1072149 mem = 536879218 peak = 1070661632
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 280959, 26, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (298, 391, 753)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1663)
[M::mem_pestat] mean and std.dev: (463.18, 287.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2118)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 240, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 706)
[M::mem_pestat] mean and std.dev: (262.86, 126.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 887)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 496, 711)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1725)
[M::mem_pestat] mean and std.dev: (373.64, 258.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2232)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 409, 1083)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2843)
[M::mem_pestat] mean and std.dev: (681.91, 663.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3723)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697910 sequences (100000117 bp) in 2.685 CPU sec, 2.866 real sec...
[M::process] read 697694 sequences (100000216 bp) in 2.030 CPU sec, 2.033 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 282293, 22, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 286, 695)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1735)
[M::mem_pestat] mean and std.dev: (366.18, 341.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2255)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 232, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 686)
[M::mem_pestat] mean and std.dev: (255.80, 124.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 862)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 438, 2068)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5794)
[M::mem_pestat] mean and std.dev: (946.59, 924.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7657)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (311, 528, 1812)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4814)
[M::mem_pestat] mean and std.dev: (914.78, 850.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6315)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695424 reads in 194.845 CPU sec, 6.458 real sec
sorting block 66, #reads = 1070543 mem = 536878652 peak = 1070661632
[M::mem_process_seqs] Processed 698766 reads in 124.342 CPU sec, 3.945 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 281877, 43, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (262, 481, 1024)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2548)
[M::mem_pestat] mean and std.dev: (625.86, 481.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3310)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 234, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 696)
[M::mem_pestat] mean and std.dev: (258.31, 126.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 875)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (508, 824, 1409)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3211)
[M::mem_pestat] mean and std.dev: (900.05, 522.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4112)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (246, 268, 430)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 798)
[M::mem_pestat] mean and std.dev: (308.26, 143.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 982)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 67, #reads = 1071982 mem = 536885951 peak = 1070661632
[M::process] read 697364 sequences (100000111 bp) in 2.864 CPU sec, 3.016 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 281731, 22, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (252, 558, 1559)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4173)
[M::mem_pestat] mean and std.dev: (821.80, 832.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5480)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 236, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 700)
[M::mem_pestat] mean and std.dev: (260.07, 127.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 880)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (249, 519, 784)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1854)
[M::mem_pestat] mean and std.dev: (498.90, 403.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2389)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 323, 2133)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6057)
[M::mem_pestat] mean and std.dev: (1171.24, 1387.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8019)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696910 sequences (100000189 bp) in 1.968 CPU sec, 1.972 real sec...
[M::mem_process_seqs] Processed 697910 reads in 188.724 CPU sec, 6.079 real sec
[M::mem_process_seqs] Processed 697694 reads in 121.563 CPU sec, 3.843 real sec
sorting block 68, #reads = 1075187 mem = 536884086 peak = 1070661632
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 281875, 30, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 323, 680)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1600)
[M::mem_pestat] mean and std.dev: (404.29, 269.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2060)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 236, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 706)
[M::mem_pestat] mean and std.dev: (261.04, 128.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 888)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (109, 397, 1386)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3940)
[M::mem_pestat] mean and std.dev: (987.90, 1136.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5535)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 522, 875)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2203)
[M::mem_pestat] mean and std.dev: (535.14, 460.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2867)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696608 sequences (100000205 bp) in 2.855 CPU sec, 2.971 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 281668, 19, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (130, 228, 423)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1009)
[M::mem_pestat] mean and std.dev: (241.59, 172.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1302)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 238, 346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 716)
[M::mem_pestat] mean and std.dev: (263.42, 129.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 901)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (92, 115, 1309)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3743)
[M::mem_pestat] mean and std.dev: (542.44, 753.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4960)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (232, 304, 722)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1702)
[M::mem_pestat] mean and std.dev: (399.21, 254.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2192)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696204 sequences (100000294 bp) in 2.050 CPU sec, 2.049 real sec...
[M::mem_process_seqs] Processed 697364 reads in 188.836 CPU sec, 6.088 real sec
[M::mem_process_seqs] Processed 696910 reads in 124.611 CPU sec, 3.945 real sec
sorting block 69, #reads = 1072850 mem = 536884773 peak = 1070661632
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 281611, 35, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 1137, 1862)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5170)
[M::mem_pestat] mean and std.dev: (1216.76, 1204.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6824)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 239, 347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 719)
[M::mem_pestat] mean and std.dev: (264.30, 130.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 905)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (84, 445, 751)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2085)
[M::mem_pestat] mean and std.dev: (450.59, 376.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2752)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (231, 313, 672)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1554)
[M::mem_pestat] mean and std.dev: (403.02, 256.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1995)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696186 sequences (100000249 bp) in 2.819 CPU sec, 2.988 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 280980, 38, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (236, 612, 1741)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4751)
[M::mem_pestat] mean and std.dev: (803.13, 673.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6256)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::process] read 694960 sequences (100000185 bp) in 1.718 CPU sec, 1.720 real sec...
[M::mem_pestat] (25, 50, 75) percentile: (162, 241, 349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 723)
[M::mem_pestat] mean and std.dev: (265.85, 130.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 910)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (325, 456, 1200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2950)
[M::mem_pestat] mean and std.dev: (815.13, 706.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3825)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (251, 387, 925)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2273)
[M::mem_pestat] mean and std.dev: (534.06, 435.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2947)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696608 reads in 181.280 CPU sec, 5.775 real sec
sorting block 70, #reads = 1073785 mem = 536879164 peak = 1070661632
[M::mem_process_seqs] Processed 696204 reads in 124.095 CPU sec, 3.954 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 281473, 52, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 340, 1862)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5190)
[M::mem_pestat] mean and std.dev: (972.79, 1188.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6854)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 241, 349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 721)
[M::mem_pestat] mean and std.dev: (265.92, 130.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 907)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 553, 1283)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3529)
[M::mem_pestat] mean and std.dev: (763.19, 801.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4652)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (285, 551, 1554)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4092)
[M::mem_pestat] mean and std.dev: (897.05, 824.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5361)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694648 sequences (100000234 bp) in 2.570 CPU sec, 2.711 real sec...
[M::process] read 694854 sequences (100000123 bp) in 1.794 CPU sec, 1.798 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 281438, 38, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (242, 371, 1727)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4697)
[M::mem_pestat] mean and std.dev: (864.91, 869.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6182)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 244, 352)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 726)
[M::mem_pestat] mean and std.dev: (268.76, 131.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 913)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (74, 522, 1093)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3131)
[M::mem_pestat] mean and std.dev: (701.39, 690.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4150)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (260, 411, 973)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2399)
[M::mem_pestat] mean and std.dev: (574.80, 472.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3112)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696186 reads in 184.120 CPU sec, 5.867 real sec
sorting block 71, #reads = 1073277 mem = 536877397 peak = 1070661632
[M::mem_process_seqs] Processed 694960 reads in 123.606 CPU sec, 4.205 real sec
sorting block 72, #reads = 1072906 mem = 536885670 peak = 1070661632
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 281276, 29, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 279, 1069)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2861)
[M::mem_pestat] mean and std.dev: (568.38, 560.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3757)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 245, 354)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 732)
[M::mem_pestat] mean and std.dev: (269.94, 132.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 921)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (465, 902, 1525)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3645)
[M::mem_pestat] mean and std.dev: (1148.62, 905.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4771)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (334, 440, 1358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3406)
[M::mem_pestat] mean and std.dev: (762.31, 706.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4430)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695342 sequences (100000027 bp) in 2.811 CPU sec, 2.998 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 280464, 23, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 340, 1291)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3465)
[M::mem_pestat] mean and std.dev: (556.39, 549.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4552)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::process] read 696494 sequences (100000036 bp) in 1.783 CPU sec, 1.790 real sec...
[M::mem_pestat] (25, 50, 75) percentile: (165, 245, 355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 735)
[M::mem_pestat] mean and std.dev: (270.13, 132.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 925)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (413, 843, 1867)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4775)
[M::mem_pestat] mean and std.dev: (1008.76, 739.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6229)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (240, 382, 779)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1857)
[M::mem_pestat] mean and std.dev: (534.51, 456.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2396)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 694648 reads in 185.562 CPU sec, 6.181 real sec
[M::mem_process_seqs] Processed 694854 reads in 122.438 CPU sec, 3.978 real sec
sorting block 73, #reads = 1072749 mem = 536879440 peak = 1070661632
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 281556, 26, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 503, 1371)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3723)
[M::mem_pestat] mean and std.dev: (854.67, 879.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4899)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 243, 351)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 725)
[M::mem_pestat] mean and std.dev: (267.71, 131.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 912)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (26, 466, 1049)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3095)
[M::mem_pestat] mean and std.dev: (910.00, 1059.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5149)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 285, 870)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2260)
[M::mem_pestat] mean and std.dev: (459.29, 410.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2955)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696328 sequences (100000281 bp) in 2.756 CPU sec, 2.874 real sec...
[M::process] read 695972 sequences (100000283 bp) in 1.590 CPU sec, 1.596 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 281627, 28, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 386, 647)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1567)
[M::mem_pestat] mean and std.dev: (420.88, 293.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2027)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 238, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 710)
[M::mem_pestat] mean and std.dev: (262.85, 128.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 893)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (253, 497, 796)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1882)
[M::mem_pestat] mean and std.dev: (569.70, 464.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2426)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 507, 880)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2218)
[M::mem_pestat] mean and std.dev: (511.94, 375.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2887)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695342 reads in 188.439 CPU sec, 6.088 real sec
[M::mem_process_seqs] Processed 696494 reads in 124.034 CPU sec, 3.946 real sec
sorting block 74, #reads = 1073115 mem = 536878994 peak = 1070661632
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 282003, 21, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 367, 771)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1905)
[M::mem_pestat] mean and std.dev: (441.70, 409.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2472)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 238, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 705)
[M::mem_pestat] mean and std.dev: (262.74, 128.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 886)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (413, 544, 1438)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3488)
[M::mem_pestat] mean and std.dev: (765.95, 560.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4513)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 347, 551)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1215)
[M::mem_pestat] mean and std.dev: (413.80, 292.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1583)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695806 sequences (100000073 bp) in 2.911 CPU sec, 3.059 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 282088, 28, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (262, 355, 1107)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2797)
[M::mem_pestat] mean and std.dev: (555.69, 536.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3642)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 239, 347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 717)
[M::mem_pestat] mean and std.dev: (264.77, 129.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 902)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 245, 1021)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2623)
[M::mem_pestat] mean and std.dev: (454.12, 483.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3424)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 394, 1915)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5299)
[M::mem_pestat] mean and std.dev: (1098.15, 1344.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6991)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696060 sequences (100000119 bp) in 1.962 CPU sec, 1.965 real sec...
[M::mem_process_seqs] Processed 696328 reads in 184.812 CPU sec, 5.861 real sec
sorting block 75, #reads = 1074439 mem = 536884402 peak = 1070661632
[M::mem_process_seqs] Processed 695972 reads in 124.069 CPU sec, 3.923 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 281527, 21, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 261, 881)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2251)
[M::mem_pestat] mean and std.dev: (411.04, 327.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2936)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 239, 346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 714)
[M::mem_pestat] mean and std.dev: (263.92, 128.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 898)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (321, 717, 1667)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4359)
[M::mem_pestat] mean and std.dev: (789.68, 617.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5705)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (303, 482, 1003)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2403)
[M::mem_pestat] mean and std.dev: (702.91, 611.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3151)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 76, #reads = 1073827 mem = 536879658 peak = 1070661632
[M::process] read 695776 sequences (100000089 bp) in 2.882 CPU sec, 2.990 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 280808, 22, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (223, 425, 770)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1864)
[M::mem_pestat] mean and std.dev: (478.53, 338.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2411)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 238, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 705)
[M::mem_pestat] mean and std.dev: (262.14, 127.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 886)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (522, 863, 1853)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4515)
[M::mem_pestat] mean and std.dev: (1130.62, 964.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5846)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 332, 1078)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2866)
[M::mem_pestat] mean and std.dev: (483.45, 414.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3760)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696072 sequences (100000117 bp) in 1.949 CPU sec, 1.950 real sec...
[M::mem_process_seqs] Processed 695806 reads in 191.893 CPU sec, 6.134 real sec
[M::mem_process_seqs] Processed 696060 reads in 126.238 CPU sec, 3.996 real sec
sorting block 77, #reads = 1070911 mem = 536879009 peak = 1070661632
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 281283, 21, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 368, 1001)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2561)
[M::mem_pestat] mean and std.dev: (532.82, 526.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3341)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 238, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 705)
[M::mem_pestat] mean and std.dev: (262.69, 127.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 886)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (344, 1021, 2734)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7514)
[M::mem_pestat] mean and std.dev: (1546.52, 1626.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9904)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 237, 393)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 801)
[M::mem_pestat] mean and std.dev: (256.76, 120.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1005)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696128 sequences (100000179 bp) in 2.874 CPU sec, 3.012 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 281157, 23, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 569, 2768)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7916)
[M::mem_pestat] mean and std.dev: (1622.04, 2032.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10490)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 237, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 699)
[M::mem_pestat] mean and std.dev: (261.15, 126.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 878)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 602, 1276)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3430)
[M::mem_pestat] mean and std.dev: (732.43, 694.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4507)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (256, 418, 1193)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3067)
[M::mem_pestat] mean and std.dev: (548.90, 432.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4004)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695730 sequences (100000137 bp) in 1.906 CPU sec, 1.913 real sec...
[M::mem_process_seqs] Processed 695776 reads in 189.096 CPU sec, 6.016 real sec
sorting block 78, #reads = 1072006 mem = 536879756 peak = 1070661632
[M::mem_process_seqs] Processed 696072 reads in 127.665 CPU sec, 4.353 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 281419, 18, 22)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 276, 944)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2478)
[M::mem_pestat] mean and std.dev: (482.03, 478.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3245)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 237, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 698)
[M::mem_pestat] mean and std.dev: (260.59, 125.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 877)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 1012, 1430)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3922)
[M::mem_pestat] mean and std.dev: (861.00, 819.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5168)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 310, 801)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2101)
[M::mem_pestat] mean and std.dev: (407.84, 361.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2751)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695976 sequences (100000271 bp) in 2.639 CPU sec, 2.765 real sec...
[M::process] read 695500 sequences (100000080 bp) in 1.912 CPU sec, 1.914 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 280895, 39, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 431, 851)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2195)
[M::mem_pestat] mean and std.dev: (551.69, 500.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2867)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 238, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 696)
[M::mem_pestat] mean and std.dev: (261.03, 125.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 874)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (432, 1197, 2544)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6768)
[M::mem_pestat] mean and std.dev: (1975.62, 2044.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10155)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 311, 821)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2019)
[M::mem_pestat] mean and std.dev: (475.07, 389.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2618)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696128 reads in 189.411 CPU sec, 6.324 real sec
sorting block 79, #reads = 1072158 mem = 536881241 peak = 1070661632
[M::mem_process_seqs] Processed 695730 reads in 123.263 CPU sec, 4.029 real sec
sorting block 80, #reads = 1072313 mem = 536879091 peak = 1094807552
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 280569, 30, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 294, 835)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2063)
[M::mem_pestat] mean and std.dev: (387.52, 313.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2677)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 238, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 699)
[M::mem_pestat] mean and std.dev: (261.14, 125.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 878)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (389, 873, 1128)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2606)
[M::mem_pestat] mean and std.dev: (804.04, 602.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3345)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 365, 1331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3571)
[M::mem_pestat] mean and std.dev: (537.85, 549.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4691)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695468 sequences (100000101 bp) in 2.639 CPU sec, 2.781 real sec...
[M::process] read 695866 sequences (100000128 bp) in 1.874 CPU sec, 1.875 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 281119, 25, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 231, 1059)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2859)
[M::mem_pestat] mean and std.dev: (723.90, 877.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4234)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 239, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 700)
[M::mem_pestat] mean and std.dev: (262.32, 126.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 879)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (425, 806, 1638)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4064)
[M::mem_pestat] mean and std.dev: (860.91, 785.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5277)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (444, 1153, 2063)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5301)
[M::mem_pestat] mean and std.dev: (1007.32, 1011.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6920)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695976 reads in 188.848 CPU sec, 6.118 real sec
[M::mem_process_seqs] Processed 695500 reads in 126.353 CPU sec, 4.018 real sec
sorting block 81, #reads = 1071634 mem = 536878682 peak = 1094807552
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 280767, 21, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 481, 1755)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4905)
[M::mem_pestat] mean and std.dev: (1086.13, 1226.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6480)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 239, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 703)
[M::mem_pestat] mean and std.dev: (262.49, 126.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 883)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (316, 485, 1086)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2626)
[M::mem_pestat] mean and std.dev: (482.06, 305.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3396)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 349, 987)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2567)
[M::mem_pestat] mean and std.dev: (590.76, 531.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3357)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696264 sequences (100000124 bp) in 2.988 CPU sec, 3.112 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 281285, 15, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 361, 668)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1638)
[M::mem_pestat] mean and std.dev: (435.05, 324.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2123)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 238, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 699)
[M::mem_pestat] mean and std.dev: (261.86, 127.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 878)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (133, 213, 1337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3745)
[M::mem_pestat] mean and std.dev: (587.29, 653.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4949)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 313, 1242)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3396)
[M::mem_pestat] mean and std.dev: (660.00, 837.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4473)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696032 sequences (100000102 bp) in 2.045 CPU sec, 2.051 real sec...
[M::mem_process_seqs] Processed 695468 reads in 184.507 CPU sec, 5.856 real sec
[M::mem_process_seqs] Processed 695866 reads in 124.672 CPU sec, 3.938 real sec
sorting block 82, #reads = 1071895 mem = 536883984 peak = 1094807552
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 281892, 44, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (271, 334, 617)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1309)
[M::mem_pestat] mean and std.dev: (341.34, 205.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1655)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 237, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 699)
[M::mem_pestat] mean and std.dev: (261.19, 126.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 878)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (262, 568, 927)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2257)
[M::mem_pestat] mean and std.dev: (533.45, 393.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2922)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (235, 309, 555)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1195)
[M::mem_pestat] mean and std.dev: (371.90, 231.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1515)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695496 sequences (100000037 bp) in 3.384 CPU sec, 3.518 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 282000, 16, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 319, 782)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1920)
[M::mem_pestat] mean and std.dev: (487.19, 423.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2489)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 237, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 699)
[M::mem_pestat] mean and std.dev: (261.52, 126.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 878)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (411, 769, 1811)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4611)
[M::mem_pestat] mean and std.dev: (868.38, 602.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6011)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 285, 868)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2170)
[M::mem_pestat] mean and std.dev: (448.15, 366.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2821)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695250 sequences (100000278 bp) in 2.020 CPU sec, 2.017 real sec...
[M::mem_process_seqs] Processed 696264 reads in 187.149 CPU sec, 5.931 real sec
sorting block 83, #reads = 1072308 mem = 536881916 peak = 1094807552
[M::mem_process_seqs] Processed 696032 reads in 126.093 CPU sec, 4.263 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 281288, 15, 76)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (145, 252, 551)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1363)
[M::mem_pestat] mean and std.dev: (394.90, 369.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1874)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 239, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 697)
[M::mem_pestat] mean and std.dev: (261.97, 125.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 875)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (100, 601, 1560)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4480)
[M::mem_pestat] mean and std.dev: (744.67, 688.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5940)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (290, 502, 956)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2288)
[M::mem_pestat] mean and std.dev: (549.66, 474.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2954)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 84, #reads = 1072950 mem = 536881340 peak = 1094807552
[M::process] read 695100 sequences (100000171 bp) in 2.954 CPU sec, 3.091 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 281507, 27, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (326, 482, 1250)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3098)
[M::mem_pestat] mean and std.dev: (562.46, 448.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4022)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 239, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 700)
[M::mem_pestat] mean and std.dev: (262.46, 126.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 879)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (336, 862, 1270)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3138)
[M::mem_pestat] mean and std.dev: (851.19, 682.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4072)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 355, 965)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2465)
[M::mem_pestat] mean and std.dev: (544.86, 506.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3215)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694588 sequences (100000264 bp) in 1.910 CPU sec, 1.914 real sec...
[M::mem_process_seqs] Processed 695496 reads in 187.731 CPU sec, 6.241 real sec
[M::mem_process_seqs] Processed 695250 reads in 122.928 CPU sec, 4.006 real sec
sorting block 85, #reads = 1072312 mem = 536883143 peak = 1094807552
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 281213, 23, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 331, 535)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1267)
[M::mem_pestat] mean and std.dev: (346.54, 240.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1633)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 241, 345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 707)
[M::mem_pestat] mean and std.dev: (264.39, 127.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 888)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (391, 803, 2361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6301)
[M::mem_pestat] mean and std.dev: (1522.96, 1456.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8271)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 247, 1214)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3320)
[M::mem_pestat] mean and std.dev: (454.31, 544.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4373)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694506 sequences (100000285 bp) in 2.823 CPU sec, 2.957 real sec...
[M::process] read 694798 sequences (100000061 bp) in 1.711 CPU sec, 1.714 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 281115, 17, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 284, 693)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1657)
[M::mem_pestat] mean and std.dev: (387.23, 306.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2139)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 242, 346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 708)
[M::mem_pestat] mean and std.dev: (265.18, 127.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 889)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 386, 1380)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3708)
[M::mem_pestat] mean and std.dev: (598.50, 517.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4872)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 286, 840)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2192)
[M::mem_pestat] mean and std.dev: (485.69, 487.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2868)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695100 reads in 189.902 CPU sec, 6.155 real sec
sorting block 86, #reads = 1073153 mem = 536881677 peak = 1094807552
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 280871, 17, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 410, 1487)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4043)
[M::mem_pestat] mean and std.dev: (704.61, 666.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5321)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 243, 347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 711)
[M::mem_pestat] mean and std.dev: (265.65, 127.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 893)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (403, 981, 3484)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9646)
[M::mem_pestat] mean and std.dev: (1655.82, 1471.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12727)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (326, 458, 897)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2039)
[M::mem_pestat] mean and std.dev: (586.92, 409.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2610)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694096 sequences (100000240 bp) in 2.261 CPU sec, 2.271 real sec...
[M::mem_process_seqs] Processed 694506 reads in 109.518 CPU sec, 3.575 real sec
[M::mem_process_seqs] Processed 694588 reads in 270.875 CPU sec, 8.718 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 281155, 25, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (305, 978, 1744)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4622)
[M::mem_pestat] mean and std.dev: (1198.03, 1028.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6061)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 243, 347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 711)
[M::mem_pestat] mean and std.dev: (265.85, 128.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 893)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (320, 807, 1144)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2792)
[M::mem_pestat] mean and std.dev: (726.12, 412.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3616)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (275, 598, 1550)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4100)
[M::mem_pestat] mean and std.dev: (986.81, 953.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5375)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 87, #reads = 1071282 mem = 536883580 peak = 1094807552
[M::process] read 703816 sequences (100000040 bp) in 2.681 CPU sec, 3.026 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 281089, 29, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 450, 842)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2170)
[M::mem_pestat] mean and std.dev: (445.05, 363.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2834)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 243, 348)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 714)
[M::mem_pestat] mean and std.dev: (266.44, 128.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 897)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (508, 751, 2555)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6649)
[M::mem_pestat] mean and std.dev: (1307.11, 1346.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8696)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 338, 958)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2466)
[M::mem_pestat] mean and std.dev: (595.09, 531.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3220)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 694798 reads in 211.874 CPU sec, 6.722 real sec
[M::process] read 703912 sequences (100000116 bp) in 2.022 CPU sec, 2.046 real sec...
[M::mem_process_seqs] Processed 694096 reads in 130.455 CPU sec, 4.114 real sec
sorting block 88, #reads = 1072460 mem = 536876634 peak = 1094807552
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 284187, 26, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (228, 413, 985)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2499)
[M::mem_pestat] mean and std.dev: (564.53, 555.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3256)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 217, 315)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 645)
[M::mem_pestat] mean and std.dev: (242.55, 119.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 810)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (107, 710, 1194)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3368)
[M::mem_pestat] mean and std.dev: (933.80, 912.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4582)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 262, 536)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1284)
[M::mem_pestat] mean and std.dev: (362.74, 324.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1659)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703008 sequences (100000070 bp) in 2.686 CPU sec, 2.840 real sec...
[M::process] read 702870 sequences (100000157 bp) in 1.879 CPU sec, 1.882 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 284166, 30, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 401, 1031)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2725)
[M::mem_pestat] mean and std.dev: (621.00, 602.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3572)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 216, 315)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 645)
[M::mem_pestat] mean and std.dev: (242.47, 119.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 810)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (125, 297, 1119)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3107)
[M::mem_pestat] mean and std.dev: (543.93, 623.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4101)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 334, 422)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 910)
[M::mem_pestat] mean and std.dev: (288.38, 161.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1154)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703816 reads in 199.772 CPU sec, 6.349 real sec
[M::mem_process_seqs] Processed 703912 reads in 131.091 CPU sec, 4.162 real sec
sorting block 89, #reads = 1071820 mem = 536880600 peak = 1094807552
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 283794, 15, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (253, 403, 1270)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3304)
[M::mem_pestat] mean and std.dev: (684.30, 770.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4321)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 218, 318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 652)
[M::mem_pestat] mean and std.dev: (244.81, 121.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 819)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (685, 879, 1798)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4024)
[M::mem_pestat] mean and std.dev: (1370.80, 1009.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5408)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (250, 330, 1797)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4891)
[M::mem_pestat] mean and std.dev: (807.85, 781.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6438)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703004 sequences (100000099 bp) in 2.957 CPU sec, 3.069 real sec...
[M::process] read 701790 sequences (100000284 bp) in 2.060 CPU sec, 2.063 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 284533, 24, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 310, 1154)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3064)
[M::mem_pestat] mean and std.dev: (636.39, 500.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4019)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 219, 320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 656)
[M::mem_pestat] mean and std.dev: (245.89, 121.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 824)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 307, 651)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1601)
[M::mem_pestat] mean and std.dev: (406.82, 372.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2076)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 287, 757)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1907)
[M::mem_pestat] mean and std.dev: (433.62, 318.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2482)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703008 reads in 206.051 CPU sec, 6.584 real sec
sorting block 90, #reads = 1073964 mem = 536880519 peak = 1094807552
[M::process] read 700958 sequences (100000000 bp) in 2.141 CPU sec, 2.150 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 284230, 23, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 349, 1209)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3215)
[M::mem_pestat] mean and std.dev: (602.77, 590.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4218)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 219, 320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 656)
[M::mem_pestat] mean and std.dev: (245.76, 121.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 824)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (424, 826, 1419)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3409)
[M::mem_pestat] mean and std.dev: (1081.70, 856.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4509)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 386, 526)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1142)
[M::mem_pestat] mean and std.dev: (365.47, 197.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1450)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703004 reads in 113.437 CPU sec, 3.635 real sec
sorting block 91, #reads = 1072903 mem = 536879347 peak = 1094807552
[M::mem_process_seqs] Processed 702870 reads in 287.854 CPU sec, 9.185 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 283630, 20, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 209, 786)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2050)
[M::mem_pestat] mean and std.dev: (427.46, 426.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2682)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 223, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 669)
[M::mem_pestat] mean and std.dev: (249.26, 123.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 841)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (68, 234, 1323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3833)
[M::mem_pestat] mean and std.dev: (511.32, 654.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5088)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 380, 1354)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3610)
[M::mem_pestat] mean and std.dev: (717.56, 667.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4738)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699498 sequences (100000293 bp) in 2.644 CPU sec, 2.764 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 284219, 30, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (315, 454, 1165)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2865)
[M::mem_pestat] mean and std.dev: (692.96, 554.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3715)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 225, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 682)
[M::mem_pestat] mean and std.dev: (252.46, 125.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 858)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (250, 440, 1158)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2974)
[M::mem_pestat] mean and std.dev: (498.20, 438.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3882)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (294, 568, 767)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1713)
[M::mem_pestat] mean and std.dev: (526.23, 296.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2186)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699642 sequences (100000227 bp) in 2.073 CPU sec, 2.074 real sec...
[M::mem_process_seqs] Processed 701790 reads in 233.836 CPU sec, 7.478 real sec
sorting block 92, #reads = 1073383 mem = 536878712 peak = 1094807552
[M::mem_process_seqs] Processed 700958 reads in 135.898 CPU sec, 4.435 real sec
sorting block 93, #reads = 1071249 mem = 536886506 peak = 1094807552
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 283094, 32, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (295, 622, 2090)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5680)
[M::mem_pestat] mean and std.dev: (1174.50, 1187.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7475)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 230, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 696)
[M::mem_pestat] mean and std.dev: (256.42, 126.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 876)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (256, 1018, 3027)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8569)
[M::mem_pestat] mean and std.dev: (1298.28, 1696.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11340)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (295, 430, 1096)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2698)
[M::mem_pestat] mean and std.dev: (630.88, 596.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3499)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699664 sequences (100000010 bp) in 3.156 CPU sec, 3.349 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 283372, 27, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (230, 367, 979)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2477)
[M::mem_pestat] mean and std.dev: (701.09, 695.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3482)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 229, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 694)
[M::mem_pestat] mean and std.dev: (256.35, 126.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 873)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (282, 478, 1529)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4023)
[M::mem_pestat] mean and std.dev: (884.12, 1018.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5270)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (246, 429, 1822)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4974)
[M::mem_pestat] mean and std.dev: (769.03, 667.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6550)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700254 sequences (100000147 bp) in 2.081 CPU sec, 2.091 real sec...
[M::mem_process_seqs] Processed 699498 reads in 203.449 CPU sec, 6.597 real sec
[M::mem_process_seqs] Processed 699642 reads in 132.058 CPU sec, 4.196 real sec
sorting block 94, #reads = 1073190 mem = 536879115 peak = 1094807552
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 283764, 25, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 469, 2626)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7502)
[M::mem_pestat] mean and std.dev: (1485.22, 1988.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9940)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 229, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 696)
[M::mem_pestat] mean and std.dev: (256.22, 127.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 876)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (548, 971, 1307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2825)
[M::mem_pestat] mean and std.dev: (818.55, 537.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3584)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 289, 717)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1721)
[M::mem_pestat] mean and std.dev: (428.60, 316.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2223)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701488 sequences (100000029 bp) in 2.965 CPU sec, 3.084 real sec...
[M::process] read 702454 sequences (100000043 bp) in 1.650 CPU sec, 1.651 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 283628, 15, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 304, 563)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1295)
[M::mem_pestat] mean and std.dev: (306.31, 208.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1661)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 227, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 684)
[M::mem_pestat] mean and std.dev: (253.35, 124.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 860)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (499, 1121, 1493)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3481)
[M::mem_pestat] mean and std.dev: (1100.80, 704.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4475)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (280, 465, 753)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1699)
[M::mem_pestat] mean and std.dev: (477.03, 317.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2172)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699664 reads in 191.294 CPU sec, 6.089 real sec
[M::mem_process_seqs] Processed 700254 reads in 123.108 CPU sec, 3.905 real sec
sorting block 95, #reads = 1072868 mem = 536878797 peak = 1094807552
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 283816, 28, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (146, 282, 632)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1604)
[M::mem_pestat] mean and std.dev: (353.69, 254.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2090)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 223, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 664)
[M::mem_pestat] mean and std.dev: (249.13, 122.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 834)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (527, 1522, 4798)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13340)
[M::mem_pestat] mean and std.dev: (2326.43, 2004.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17611)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 522, 1051)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2825)
[M::mem_pestat] mean and std.dev: (701.29, 661.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3712)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702196 sequences (100000172 bp) in 2.689 CPU sec, 2.835 real sec...
[M::process] read 702192 sequences (100000203 bp) in 1.959 CPU sec, 1.962 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 283870, 20, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 377, 753)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1923)
[M::mem_pestat] mean and std.dev: (470.06, 355.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2508)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 220, 319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 653)
[M::mem_pestat] mean and std.dev: (245.59, 120.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 820)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (303, 875, 1895)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5079)
[M::mem_pestat] mean and std.dev: (1063.50, 886.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6671)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (257, 550, 2568)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7190)
[M::mem_pestat] mean and std.dev: (1247.81, 1681.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9501)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701488 reads in 197.165 CPU sec, 6.278 real sec
sorting block 96, #reads = 1074163 mem = 536886386 peak = 1094807552
[M::mem_process_seqs] Processed 702454 reads in 133.923 CPU sec, 4.312 real sec
sorting block 97, #reads = 1071616 mem = 536885325 peak = 1094807552
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 284092, 22, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 447, 1189)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3175)
[M::mem_pestat] mean and std.dev: (749.52, 771.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4168)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 220, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 659)
[M::mem_pestat] mean and std.dev: (246.39, 120.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 828)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (795, 1709, 2797)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6801)
[M::mem_pestat] mean and std.dev: (1803.23, 1083.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8803)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 285, 479)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1063)
[M::mem_pestat] mean and std.dev: (274.47, 130.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1355)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702198 sequences (100000199 bp) in 2.890 CPU sec, 3.012 real sec...
[M::process] read 701068 sequences (100000033 bp) in 2.139 CPU sec, 2.148 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 284061, 21, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 391, 1114)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2992)
[M::mem_pestat] mean and std.dev: (567.94, 561.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3931)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 221, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 657)
[M::mem_pestat] mean and std.dev: (246.96, 121.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 825)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (325, 1270, 2281)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6193)
[M::mem_pestat] mean and std.dev: (1253.52, 926.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8149)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 409, 1543)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4187)
[M::mem_pestat] mean and std.dev: (717.10, 676.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5509)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702196 reads in 218.422 CPU sec, 7.010 real sec
[M::mem_process_seqs] Processed 702192 reads in 140.109 CPU sec, 4.564 real sec
sorting block 98, #reads = 1071124 mem = 536881825 peak = 1094807552
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 283919, 25, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 270, 894)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2306)
[M::mem_pestat] mean and std.dev: (501.61, 511.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3012)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 221, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 659)
[M::mem_pestat] mean and std.dev: (247.02, 121.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 828)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (734, 1318, 2544)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6164)
[M::mem_pestat] mean and std.dev: (1612.71, 1308.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7974)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (289, 632, 1937)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5233)
[M::mem_pestat] mean and std.dev: (891.03, 794.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6881)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700136 sequences (100000235 bp) in 2.705 CPU sec, 2.803 real sec...
[M::process] read 699694 sequences (100000105 bp) in 1.640 CPU sec, 1.644 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 283683, 27, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (261, 363, 994)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2460)
[M::mem_pestat] mean and std.dev: (621.39, 587.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3193)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 224, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 667)
[M::mem_pestat] mean and std.dev: (249.89, 122.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 838)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (139, 359, 849)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2269)
[M::mem_pestat] mean and std.dev: (519.30, 467.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2979)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 367, 997)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2669)
[M::mem_pestat] mean and std.dev: (553.61, 548.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3505)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702198 reads in 200.007 CPU sec, 6.470 real sec
[M::mem_process_seqs] Processed 701068 reads in 128.713 CPU sec, 4.196 real sec
sorting block 99, #reads = 1069825 mem = 536881675 peak = 1094807552
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 283239, 36, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 321, 719)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1829)
[M::mem_pestat] mean and std.dev: (304.78, 196.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2384)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 227, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 678)
[M::mem_pestat] mean and std.dev: (253.04, 124.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 852)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (130, 384, 717)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1891)
[M::mem_pestat] mean and std.dev: (531.94, 556.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2759)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 374, 1197)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3285)
[M::mem_pestat] mean and std.dev: (684.16, 702.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4329)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699698 sequences (100000061 bp) in 2.940 CPU sec, 3.075 real sec...
[M::process] read 703872 sequences (100000148 bp) in 1.650 CPU sec, 1.658 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 283318, 12, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 277, 980)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2524)
[M::mem_pestat] mean and std.dev: (579.36, 473.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3296)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 228, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 678)
[M::mem_pestat] mean and std.dev: (252.61, 123.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 852)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (830, 1298, 1943)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4169)
[M::mem_pestat] mean and std.dev: (1468.67, 997.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5457)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 466, 793)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1951)
[M::mem_pestat] mean and std.dev: (513.37, 440.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2530)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700136 reads in 198.543 CPU sec, 6.435 real sec
sorting block 100, #reads = 1069414 mem = 536886363 peak = 1094807552
[M::mem_process_seqs] Processed 699694 reads in 129.092 CPU sec, 4.121 real sec
sorting block 101, #reads = 1072872 mem = 536878835 peak = 1094807552
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 282755, 27, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (226, 376, 1210)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3178)
[M::mem_pestat] mean and std.dev: (709.16, 699.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4162)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::process] read 700512 sequences (100000276 bp) in 2.279 CPU sec, 2.387 real sec...
[M::mem_pestat] (25, 50, 75) percentile: (156, 227, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 678)
[M::mem_pestat] mean and std.dev: (252.96, 124.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 852)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (17, 173, 891)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2639)
[M::mem_pestat] mean and std.dev: (446.00, 532.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3513)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 550, 1038)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2682)
[M::mem_pestat] mean and std.dev: (697.59, 666.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3504)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700040 sequences (100000061 bp) in 1.510 CPU sec, 1.506 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 283700, 27, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 432, 894)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2254)
[M::mem_pestat] mean and std.dev: (518.34, 366.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2934)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 216, 315)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 645)
[M::mem_pestat] mean and std.dev: (242.18, 117.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 810)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (285, 682, 2994)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8412)
[M::mem_pestat] mean and std.dev: (1348.30, 1334.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11121)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 377, 848)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2128)
[M::mem_pestat] mean and std.dev: (510.45, 469.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2768)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699698 reads in 210.392 CPU sec, 6.712 real sec
[M::mem_process_seqs] Processed 703872 reads in 151.556 CPU sec, 5.182 real sec
sorting block 102, #reads = 1067516 mem = 536888227 peak = 1094807552
[M::process] read 698894 sequences (100000054 bp) in 2.261 CPU sec, 2.368 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 282377, 37, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 276, 609)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1491)
[M::mem_pestat] mean and std.dev: (358.69, 265.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1932)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 225, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 668)
[M::mem_pestat] mean and std.dev: (250.68, 122.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 839)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 486, 2197)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6211)
[M::mem_pestat] mean and std.dev: (1079.73, 1098.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8218)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 516, 738)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1762)
[M::mem_pestat] mean and std.dev: (480.42, 327.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2274)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698450 sequences (100000162 bp) in 1.520 CPU sec, 1.528 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 282724, 21, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 249, 488)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1126)
[M::mem_pestat] mean and std.dev: (301.55, 192.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1445)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 226, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 666)
[M::mem_pestat] mean and std.dev: (250.40, 121.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 836)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 499, 1138)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3056)
[M::mem_pestat] mean and std.dev: (536.63, 402.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4015)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 324, 627)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1513)
[M::mem_pestat] mean and std.dev: (389.65, 300.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1956)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 282480, 24, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 282, 483)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1099)
[M::mem_pestat] mean and std.dev: (316.19, 185.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1407)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 229, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 679)
[M::mem_pestat] mean and std.dev: (254.53, 124.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 853)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (106, 805, 1983)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5737)
[M::mem_pestat] mean and std.dev: (924.30, 944.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7614)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 354, 852)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2146)
[M::mem_pestat] mean and std.dev: (529.31, 421.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2793)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700512 reads in 302.519 CPU sec, 10.010 real sec
[M::mem_process_seqs] Processed 700040 reads in 231.566 CPU sec, 7.451 real sec
sorting block 103, #reads = 1060793 mem = 536881700 peak = 1094807552
[M::mem_process_seqs] Processed 698894 reads in 250.646 CPU sec, 8.077 real sec
[M::process] read 698948 sequences (100000048 bp) in 2.532 CPU sec, 2.636 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 282027, 22, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 339, 808)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2024)
[M::mem_pestat] mean and std.dev: (409.41, 330.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2632)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 230, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 680)
[M::mem_pestat] mean and std.dev: (255.01, 124.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 854)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (462, 1056, 1540)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3696)
[M::mem_pestat] mean and std.dev: (889.21, 606.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4774)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 354, 469)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1009)
[M::mem_pestat] mean and std.dev: (323.55, 193.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1279)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 104, #reads = 1065062 mem = 536879577 peak = 1094807552
[M::process] read 698562 sequences (100000132 bp) in 2.297 CPU sec, 2.415 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 281923, 30, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (143, 361, 1175)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3239)
[M::mem_pestat] mean and std.dev: (640.07, 611.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4271)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 228, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 682)
[M::mem_pestat] mean and std.dev: (254.34, 124.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 857)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (83, 429, 1493)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4313)
[M::mem_pestat] mean and std.dev: (803.17, 1042.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5723)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (255, 462, 810)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1920)
[M::mem_pestat] mean and std.dev: (484.34, 352.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2475)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699194 sequences (100000301 bp) in 1.780 CPU sec, 1.779 real sec...
[M::mem_process_seqs] Processed 698450 reads in 207.370 CPU sec, 6.614 real sec
[M::mem_process_seqs] Processed 698948 reads in 139.128 CPU sec, 4.549 real sec
sorting block 105, #reads = 1066930 mem = 536880034 peak = 1094807552
[M::process] read 699012 sequences (100000106 bp) in 2.402 CPU sec, 2.545 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 281884, 21, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 512, 1582)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4306)
[M::mem_pestat] mean and std.dev: (491.10, 360.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5668)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 230, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 680)
[M::mem_pestat] mean and std.dev: (255.15, 124.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 854)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 410, 910)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2292)
[M::mem_pestat] mean and std.dev: (415.78, 307.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2983)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 386, 735)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1763)
[M::mem_pestat] mean and std.dev: (434.26, 319.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2277)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698336 sequences (100000167 bp) in 1.917 CPU sec, 1.920 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 282068, 13, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (130, 253, 963)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2629)
[M::mem_pestat] mean and std.dev: (586.91, 702.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3462)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 228, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 673)
[M::mem_pestat] mean and std.dev: (253.07, 123.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 845)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 630, 3949)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 11461)
[M::mem_pestat] mean and std.dev: (1802.00, 2279.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 15217)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 294, 1020)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2624)
[M::mem_pestat] mean and std.dev: (619.00, 672.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3426)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 282194, 27, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (248, 442, 1485)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3959)
[M::mem_pestat] mean and std.dev: (754.41, 769.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5196)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 228, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 673)
[M::mem_pestat] mean and std.dev: (253.04, 123.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 845)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (409, 582, 2404)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6394)
[M::mem_pestat] mean and std.dev: (1273.23, 1236.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8389)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 303, 432)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 864)
[M::mem_pestat] mean and std.dev: (282.38, 127.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1080)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698562 reads in 288.245 CPU sec, 9.350 real sec
sorting block 106, #reads = 1065744 mem = 536881985 peak = 1094807552
[M::mem_process_seqs] Processed 699012 reads in 217.548 CPU sec, 6.963 real sec
[M::mem_process_seqs] Processed 699194 reads in 241.277 CPU sec, 7.746 real sec
sorting block 107, #reads = 1065080 mem = 536877647 peak = 1094807552
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 282133, 40, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 363, 1255)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3331)
[M::mem_pestat] mean and std.dev: (721.06, 709.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4369)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 230, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 686)
[M::mem_pestat] mean and std.dev: (255.91, 125.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 862)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 287, 728)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1824)
[M::mem_pestat] mean and std.dev: (457.28, 434.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2372)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 469, 925)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2333)
[M::mem_pestat] mean and std.dev: (507.44, 344.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3037)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 709008 sequences (100000103 bp) in 3.119 CPU sec, 3.324 real sec...
[M::mem_process_seqs] Processed 698336 reads in 110.644 CPU sec, 3.632 real sec
sorting block 108, #reads = 1065171 mem = 536881994 peak = 1094807552
[M::process] read 707986 sequences (100000135 bp) in 2.818 CPU sec, 3.016 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 285419, 25, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 236, 533)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1275)
[M::mem_pestat] mean and std.dev: (358.68, 268.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1646)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 206, 298)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 604)
[M::mem_pestat] mean and std.dev: (230.38, 111.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 757)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (93, 378, 969)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2721)
[M::mem_pestat] mean and std.dev: (492.92, 515.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3597)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (306, 677, 2080)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5628)
[M::mem_pestat] mean and std.dev: (1372.52, 1703.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8188)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704314 sequences (100000056 bp) in 1.930 CPU sec, 1.929 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 285219, 24, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 363, 502)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1098)
[M::mem_pestat] mean and std.dev: (355.55, 238.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1396)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 208, 301)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 611)
[M::mem_pestat] mean and std.dev: (232.96, 113.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 766)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (16, 292, 1206)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3586)
[M::mem_pestat] mean and std.dev: (496.25, 558.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4776)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 312, 1044)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2766)
[M::mem_pestat] mean and std.dev: (633.28, 619.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3627)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703900 sequences (100000029 bp) in 1.900 CPU sec, 1.898 real sec...
[M::mem_process_seqs] Processed 709008 reads in 212.268 CPU sec, 6.697 real sec
sorting block 109, #reads = 1063621 mem = 536885644 peak = 1094807552
[M::mem_process_seqs] Processed 707986 reads in 142.319 CPU sec, 4.505 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 284618, 34, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 785, 1583)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4321)
[M::mem_pestat] mean and std.dev: (850.65, 816.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5690)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 217, 314)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 640)
[M::mem_pestat] mean and std.dev: (241.88, 118.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 803)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (269, 986, 1673)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4481)
[M::mem_pestat] mean and std.dev: (1135.87, 1169.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5885)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 312, 719)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1881)
[M::mem_pestat] mean and std.dev: (462.06, 439.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2462)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704002 sequences (100000219 bp) in 2.814 CPU sec, 2.957 real sec...
[M::process] read 702460 sequences (100000046 bp) in 1.460 CPU sec, 1.463 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 283971, 24, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 307, 761)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1873)
[M::mem_pestat] mean and std.dev: (435.74, 348.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2429)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 215, 312)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 636)
[M::mem_pestat] mean and std.dev: (240.60, 117.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 798)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (516, 1367, 4108)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 11292)
[M::mem_pestat] mean and std.dev: (2308.17, 2679.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14884)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 264, 1008)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2624)
[M::mem_pestat] mean and std.dev: (581.17, 562.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3432)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703900 reads in 191.069 CPU sec, 6.076 real sec
sorting block 110, #reads = 1064022 mem = 536880958 peak = 1094807552
[M::mem_process_seqs] Processed 704314 reads in 217.101 CPU sec, 6.930 real sec
sorting block 111, #reads = 1068341 mem = 536879877 peak = 1094807552
[M::process] read 701356 sequences (100000034 bp) in 2.234 CPU sec, 2.343 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 284887, 30, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 288, 838)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2148)
[M::mem_pestat] mean and std.dev: (434.56, 403.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2803)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 216, 314)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 642)
[M::mem_pestat] mean and std.dev: (242.26, 118.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 806)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (310, 670, 1996)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5368)
[M::mem_pestat] mean and std.dev: (1363.72, 1568.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7639)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (238, 285, 671)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1537)
[M::mem_pestat] mean and std.dev: (413.12, 324.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1970)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701138 sequences (100000228 bp) in 1.480 CPU sec, 1.482 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 283954, 26, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 338, 743)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1875)
[M::mem_pestat] mean and std.dev: (511.11, 497.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2500)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 220, 320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 656)
[M::mem_pestat] mean and std.dev: (246.08, 120.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 824)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (278, 1648, 2627)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7325)
[M::mem_pestat] mean and std.dev: (1774.77, 1473.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9674)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 483, 950)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2412)
[M::mem_pestat] mean and std.dev: (662.10, 552.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3143)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704002 reads in 198.779 CPU sec, 6.324 real sec
[M::process] read 700152 sequences (100000000 bp) in 2.022 CPU sec, 2.029 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 283888, 23, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 401, 1620)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4522)
[M::mem_pestat] mean and std.dev: (853.69, 842.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5973)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 223, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 667)
[M::mem_pestat] mean and std.dev: (249.09, 121.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 838)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (324, 928, 1404)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3564)
[M::mem_pestat] mean and std.dev: (778.95, 534.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4644)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (309, 507, 1234)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3084)
[M::mem_pestat] mean and std.dev: (756.97, 533.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4009)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701356 reads in 107.143 CPU sec, 3.399 real sec
sorting block 112, #reads = 1066597 mem = 536878313 peak = 1094807552
[M::mem_process_seqs] Processed 702460 reads in 347.485 CPU sec, 11.071 real sec
sorting block 113, #reads = 1068295 mem = 536879441 peak = 1094807552
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 283586, 41, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (270, 711, 1277)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3291)
[M::mem_pestat] mean and std.dev: (761.29, 645.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4298)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 224, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 670)
[M::mem_pestat] mean and std.dev: (250.26, 123.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 842)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (566, 677, 1473)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3287)
[M::mem_pestat] mean and std.dev: (850.89, 581.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4194)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (315, 557, 1105)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2685)
[M::mem_pestat] mean and std.dev: (555.73, 404.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3475)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700654 sequences (100000240 bp) in 2.762 CPU sec, 2.869 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 283660, 33, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 319, 1968)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5596)
[M::mem_pestat] mean and std.dev: (969.58, 1209.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7410)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 228, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 681)
[M::mem_pestat] mean and std.dev: (253.65, 124.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 856)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (245, 915, 3056)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8678)
[M::mem_pestat] mean and std.dev: (1946.21, 2113.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11489)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 288, 665)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1631)
[M::mem_pestat] mean and std.dev: (347.68, 247.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2114)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701720 sequences (100000105 bp) in 1.880 CPU sec, 1.880 real sec...
[M::mem_process_seqs] Processed 701138 reads in 209.261 CPU sec, 6.640 real sec
[M::mem_process_seqs] Processed 700152 reads in 122.934 CPU sec, 3.891 real sec
sorting block 114, #reads = 1068933 mem = 536887890 peak = 1094807552
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 283941, 17, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (243, 407, 866)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2112)
[M::mem_pestat] mean and std.dev: (580.80, 469.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2735)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 225, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 668)
[M::mem_pestat] mean and std.dev: (250.47, 122.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 839)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (444, 811, 1680)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4152)
[M::mem_pestat] mean and std.dev: (933.53, 674.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5388)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 391, 917)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2323)
[M::mem_pestat] mean and std.dev: (610.06, 569.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3026)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701040 sequences (100000019 bp) in 2.569 CPU sec, 2.677 real sec...
[M::process] read 701104 sequences (100000118 bp) in 1.880 CPU sec, 1.878 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 284035, 20, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 413, 1490)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4172)
[M::mem_pestat] mean and std.dev: (851.28, 962.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5513)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 222, 323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 663)
[M::mem_pestat] mean and std.dev: (247.86, 121.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 833)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (408, 899, 2600)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6984)
[M::mem_pestat] mean and std.dev: (1434.30, 1250.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9176)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 237, 719)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1885)
[M::mem_pestat] mean and std.dev: (375.47, 389.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2468)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700654 reads in 187.023 CPU sec, 5.935 real sec
[M::mem_process_seqs] Processed 701720 reads in 123.900 CPU sec, 3.930 real sec
sorting block 115, #reads = 1071290 mem = 536876836 peak = 1094807552
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 283534, 28, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 301, 933)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2445)
[M::mem_pestat] mean and std.dev: (555.55, 596.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3201)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 223, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 664)
[M::mem_pestat] mean and std.dev: (248.95, 121.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 834)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 473, 1700)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4682)
[M::mem_pestat] mean and std.dev: (918.64, 1020.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6173)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 536, 1163)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3067)
[M::mem_pestat] mean and std.dev: (639.29, 611.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4019)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700722 sequences (100000073 bp) in 2.302 CPU sec, 2.416 real sec...
[M::process] read 700724 sequences (100000222 bp) in 1.510 CPU sec, 1.503 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 283488, 27, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 477, 688)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1694)
[M::mem_pestat] mean and std.dev: (415.88, 340.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2197)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 223, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 664)
[M::mem_pestat] mean and std.dev: (248.86, 121.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 834)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 372, 1843)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5217)
[M::mem_pestat] mean and std.dev: (563.43, 614.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6904)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 424, 953)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2489)
[M::mem_pestat] mean and std.dev: (644.27, 707.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3473)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701040 reads in 186.203 CPU sec, 5.932 real sec
sorting block 116, #reads = 1072828 mem = 536879856 peak = 1094807552
[M::mem_process_seqs] Processed 701104 reads in 132.317 CPU sec, 4.230 real sec
sorting block 117, #reads = 1071318 mem = 536882015 peak = 1094807552
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 283941, 31, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (275, 450, 783)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1799)
[M::mem_pestat] mean and std.dev: (492.72, 326.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2307)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 224, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 667)
[M::mem_pestat] mean and std.dev: (249.43, 121.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 838)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (472, 730, 1765)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4351)
[M::mem_pestat] mean and std.dev: (1023.33, 770.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5644)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 502, 1875)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5271)
[M::mem_pestat] mean and std.dev: (957.50, 880.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6969)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701292 sequences (100000019 bp) in 2.746 CPU sec, 2.868 real sec...
[M::process] read 701056 sequences (100000139 bp) in 1.970 CPU sec, 1.974 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 283647, 23, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (134, 220, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 752)
[M::mem_pestat] mean and std.dev: (217.43, 108.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 958)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 224, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 668)
[M::mem_pestat] mean and std.dev: (249.96, 122.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 839)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (521, 753, 1797)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4349)
[M::mem_pestat] mean and std.dev: (718.67, 562.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5625)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 333, 645)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1485)
[M::mem_pestat] mean and std.dev: (338.34, 178.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1905)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700722 reads in 191.733 CPU sec, 6.087 real sec
[M::mem_process_seqs] Processed 700724 reads in 128.625 CPU sec, 4.073 real sec
sorting block 118, #reads = 1072980 mem = 536878099 peak = 1094807552
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 283495, 30, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (248, 335, 863)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2093)
[M::mem_pestat] mean and std.dev: (604.58, 547.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2795)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 223, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 664)
[M::mem_pestat] mean and std.dev: (249.12, 122.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 834)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (366, 1642, 1937)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5079)
[M::mem_pestat] mean and std.dev: (1276.00, 1083.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6650)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 300, 513)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1149)
[M::mem_pestat] mean and std.dev: (326.13, 163.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1467)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700478 sequences (100000274 bp) in 2.552 CPU sec, 2.664 real sec...
[M::process] read 702962 sequences (100000123 bp) in 2.010 CPU sec, 2.010 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 283165, 20, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (243, 460, 1591)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4287)
[M::mem_pestat] mean and std.dev: (864.60, 956.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5635)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 223, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 664)
[M::mem_pestat] mean and std.dev: (248.92, 121.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 834)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (730, 1134, 1907)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4261)
[M::mem_pestat] mean and std.dev: (1277.68, 854.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5438)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 283, 600)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1416)
[M::mem_pestat] mean and std.dev: (354.61, 222.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1824)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701292 reads in 202.416 CPU sec, 6.715 real sec
[M::mem_process_seqs] Processed 701056 reads in 130.467 CPU sec, 4.150 real sec
sorting block 119, #reads = 1070722 mem = 536877820 peak = 1094807552
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 283415, 25, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 428, 888)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2230)
[M::mem_pestat] mean and std.dev: (558.42, 448.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2901)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 225, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 668)
[M::mem_pestat] mean and std.dev: (250.73, 123.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 839)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (146, 438, 1018)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2762)
[M::mem_pestat] mean and std.dev: (487.74, 479.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3634)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 428, 1133)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2971)
[M::mem_pestat] mean and std.dev: (653.43, 710.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3890)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701360 sequences (100000003 bp) in 2.684 CPU sec, 2.770 real sec...
[M::process] read 698220 sequences (100000000 bp) in 1.820 CPU sec, 1.818 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 283141, 13, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 381, 1571)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4357)
[M::mem_pestat] mean and std.dev: (664.58, 683.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5750)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 219, 318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 652)
[M::mem_pestat] mean and std.dev: (244.54, 119.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 819)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (498, 664, 2347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6045)
[M::mem_pestat] mean and std.dev: (1091.92, 878.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7894)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 381, 718)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1702)
[M::mem_pestat] mean and std.dev: (458.65, 355.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2194)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700478 reads in 205.656 CPU sec, 6.537 real sec
sorting block 120, #reads = 1067255 mem = 536879579 peak = 1094807552
[M::mem_process_seqs] Processed 702962 reads in 144.994 CPU sec, 4.615 real sec
sorting block 121, #reads = 1062825 mem = 536880151 peak = 1094807552
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 282555, 19, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 570, 1603)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4411)
[M::mem_pestat] mean and std.dev: (851.18, 904.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5815)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 222, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 658)
[M::mem_pestat] mean and std.dev: (247.63, 120.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 826)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 1247, 2114)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5942)
[M::mem_pestat] mean and std.dev: (967.81, 856.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7856)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (249, 370, 826)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1980)
[M::mem_pestat] mean and std.dev: (552.04, 436.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2557)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698280 sequences (100000124 bp) in 2.719 CPU sec, 2.838 real sec...
[M::process] read 698328 sequences (100000161 bp) in 2.010 CPU sec, 2.005 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 282139, 33, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 393, 537)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1235)
[M::mem_pestat] mean and std.dev: (378.12, 268.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1584)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 231, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 692)
[M::mem_pestat] mean and std.dev: (257.15, 126.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 870)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 376, 1360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3756)
[M::mem_pestat] mean and std.dev: (673.71, 709.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4954)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 297, 601)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1351)
[M::mem_pestat] mean and std.dev: (403.68, 301.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1726)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701360 reads in 199.672 CPU sec, 6.333 real sec
[M::mem_process_seqs] Processed 698220 reads in 126.723 CPU sec, 4.027 real sec
sorting block 122, #reads = 1063989 mem = 536881371 peak = 1094807552
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 282272, 36, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 288, 1295)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3565)
[M::mem_pestat] mean and std.dev: (482.43, 558.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4700)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 230, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 689)
[M::mem_pestat] mean and std.dev: (256.46, 126.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 866)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (51, 475, 939)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2715)
[M::mem_pestat] mean and std.dev: (511.94, 544.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3603)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 448, 715)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1761)
[M::mem_pestat] mean and std.dev: (508.75, 373.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2284)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697930 sequences (100000157 bp) in 2.983 CPU sec, 3.099 real sec...
[M::process] read 697748 sequences (100000071 bp) in 1.620 CPU sec, 1.622 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 282084, 30, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (264, 519, 1242)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3198)
[M::mem_pestat] mean and std.dev: (736.77, 773.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4176)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 230, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 686)
[M::mem_pestat] mean and std.dev: (256.09, 125.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 862)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (139, 939, 1873)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5341)
[M::mem_pestat] mean and std.dev: (1267.28, 1341.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7075)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 351, 773)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1935)
[M::mem_pestat] mean and std.dev: (463.76, 444.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2516)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698280 reads in 187.844 CPU sec, 5.967 real sec
[M::mem_process_seqs] Processed 698328 reads in 124.294 CPU sec, 3.936 real sec
sorting block 123, #reads = 1069010 mem = 536878306 peak = 1094807552
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 282264, 19, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 755, 1519)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4173)
[M::mem_pestat] mean and std.dev: (853.31, 711.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5500)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 231, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 690)
[M::mem_pestat] mean and std.dev: (257.63, 126.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 867)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (392, 541, 1213)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2855)
[M::mem_pestat] mean and std.dev: (783.39, 688.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3676)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 479, 960)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2498)
[M::mem_pestat] mean and std.dev: (512.47, 445.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3267)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697644 sequences (100000136 bp) in 2.301 CPU sec, 2.416 real sec...
[M::process] read 697428 sequences (100000174 bp) in 1.510 CPU sec, 1.519 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 282129, 16, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 214, 1329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3621)
[M::mem_pestat] mean and std.dev: (472.03, 567.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4767)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 231, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 693)
[M::mem_pestat] mean and std.dev: (258.33, 127.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 871)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 329, 1792)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5050)
[M::mem_pestat] mean and std.dev: (819.07, 1141.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6679)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 646, 1578)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4328)
[M::mem_pestat] mean and std.dev: (899.91, 826.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5703)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697930 reads in 177.277 CPU sec, 5.644 real sec
[M::mem_process_seqs] Processed 697748 reads in 115.861 CPU sec, 3.689 real sec
sorting block 124, #reads = 1068649 mem = 536884366 peak = 1094807552
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 282000, 21, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 291, 840)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2106)
[M::mem_pestat] mean and std.dev: (479.55, 414.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2739)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 232, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 696)
[M::mem_pestat] mean and std.dev: (258.91, 128.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 875)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (109, 332, 685)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1837)
[M::mem_pestat] mean and std.dev: (352.89, 273.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2413)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (261, 427, 1157)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2949)
[M::mem_pestat] mean and std.dev: (714.83, 585.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3845)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697242 sequences (100000203 bp) in 2.892 CPU sec, 3.018 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 281910, 14, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 285, 448)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 962)
[M::mem_pestat] mean and std.dev: (308.97, 189.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1219)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 233, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 699)
[M::mem_pestat] mean and std.dev: (259.57, 128.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 879)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (265, 418, 489)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 937)
[M::mem_pestat] mean and std.dev: (364.67, 231.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1292)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (235, 324, 870)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2140)
[M::mem_pestat] mean and std.dev: (489.62, 413.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2775)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697258 sequences (100000096 bp) in 2.040 CPU sec, 2.036 real sec...
[M::mem_process_seqs] Processed 697644 reads in 192.280 CPU sec, 6.126 real sec
sorting block 125, #reads = 1070585 mem = 536877785 peak = 1094807552
[M::mem_process_seqs] Processed 697428 reads in 125.555 CPU sec, 4.084 real sec
sorting block 126, #reads = 1070287 mem = 536881477 peak = 1094807552
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 281993, 17, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 240, 1873)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5265)
[M::mem_pestat] mean and std.dev: (815.53, 1032.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6961)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 233, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 697)
[M::mem_pestat] mean and std.dev: (259.48, 128.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 876)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 358, 947)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2487)
[M::mem_pestat] mean and std.dev: (602.56, 689.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3359)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 261, 780)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1940)
[M::mem_pestat] mean and std.dev: (407.46, 370.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2520)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702010 sequences (100000028 bp) in 2.588 CPU sec, 2.682 real sec...
[M::process] read 703046 sequences (100000018 bp) in 1.850 CPU sec, 1.847 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 281636, 22, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 385, 551)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1255)
[M::mem_pestat] mean and std.dev: (347.24, 234.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1607)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 233, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 694)
[M::mem_pestat] mean and std.dev: (259.54, 128.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 872)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (242, 378, 1122)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2882)
[M::mem_pestat] mean and std.dev: (565.90, 581.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3762)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 292, 449)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 965)
[M::mem_pestat] mean and std.dev: (285.89, 135.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1223)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697242 reads in 201.535 CPU sec, 6.511 real sec
[M::mem_process_seqs] Processed 697258 reads in 135.588 CPU sec, 4.314 real sec
sorting block 127, #reads = 1069376 mem = 536877714 peak = 1094807552
[M::process] read 702010 sequences (100000231 bp) in 2.538 CPU sec, 2.640 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 282720, 17, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 357, 1060)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2770)
[M::mem_pestat] mean and std.dev: (575.76, 547.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3625)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 219, 319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 653)
[M::mem_pestat] mean and std.dev: (245.66, 121.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 820)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (98, 304, 941)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2627)
[M::mem_pestat] mean and std.dev: (520.94, 574.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3470)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (234, 391, 628)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1416)
[M::mem_pestat] mean and std.dev: (421.82, 245.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1810)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701076 sequences (100000103 bp) in 1.840 CPU sec, 1.845 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 283902, 35, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 242, 864)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2182)
[M::mem_pestat] mean and std.dev: (471.63, 390.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2841)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 222, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 666)
[M::mem_pestat] mean and std.dev: (248.55, 123.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 837)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (287, 1059, 2450)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6776)
[M::mem_pestat] mean and std.dev: (1543.37, 1615.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8939)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 267, 613)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1449)
[M::mem_pestat] mean and std.dev: (346.82, 300.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1867)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20, 284153, 27, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 437, 828)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2132)
[M::mem_pestat] mean and std.dev: (601.05, 481.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2784)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 218, 317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 649)
[M::mem_pestat] mean and std.dev: (244.27, 120.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 815)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (523, 1150, 2393)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6133)
[M::mem_pestat] mean and std.dev: (1273.58, 1032.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8003)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 292, 618)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1472)
[M::mem_pestat] mean and std.dev: (373.21, 253.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1899)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702010 reads in 289.179 CPU sec, 9.351 real sec
[M::mem_process_seqs] Processed 702010 reads in 203.051 CPU sec, 6.510 real sec
sorting block 128, #reads = 1056895 mem = 536878519 peak = 1094807552
[M::mem_process_seqs] Processed 703046 reads in 222.707 CPU sec, 7.197 real sec
sorting block 129, #reads = 1073480 mem = 536877667 peak = 1094807552
[M::process] read 700850 sequences (100000058 bp) in 2.526 CPU sec, 2.703 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 283663, 23, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 423, 757)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1863)
[M::mem_pestat] mean and std.dev: (491.09, 383.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2416)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 224, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 676)
[M::mem_pestat] mean and std.dev: (251.31, 125.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 850)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 412, 1311)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3619)
[M::mem_pestat] mean and std.dev: (583.48, 586.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4773)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (143, 209, 306)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 632)
[M::mem_pestat] mean and std.dev: (214.38, 100.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 795)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700688 sequences (100000064 bp) in 2.077 CPU sec, 2.310 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 283614, 10, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (263, 799, 1915)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5219)
[M::mem_pestat] mean and std.dev: (1111.69, 1111.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6871)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 224, 327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 673)
[M::mem_pestat] mean and std.dev: (251.00, 124.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 846)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (303, 650, 1880)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5034)
[M::mem_pestat] mean and std.dev: (1065.40, 911.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6611)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (300, 398, 724)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1572)
[M::mem_pestat] mean and std.dev: (418.79, 272.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1996)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701076 reads in 182.024 CPU sec, 5.882 real sec
[M::mem_process_seqs] Processed 700850 reads in 121.498 CPU sec, 3.843 real sec
sorting block 130, #reads = 1074483 mem = 536880061 peak = 1094807552
[M::process] read 698776 sequences (100000238 bp) in 1.916 CPU sec, 2.020 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 283127, 31, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (277, 682, 1879)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5083)
[M::mem_pestat] mean and std.dev: (1083.48, 977.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6685)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 225, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 677)
[M::mem_pestat] mean and std.dev: (252.08, 125.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 851)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (430, 1050, 1468)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3544)
[M::mem_pestat] mean and std.dev: (1000.67, 621.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4582)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 319, 766)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1920)
[M::mem_pestat] mean and std.dev: (431.06, 374.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2497)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698176 sequences (100000178 bp) in 2.618 CPU sec, 2.741 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 282731, 26, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 366, 1423)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3907)
[M::mem_pestat] mean and std.dev: (728.28, 731.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5149)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 232, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 698)
[M::mem_pestat] mean and std.dev: (258.27, 127.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 878)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (87, 388, 927)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2607)
[M::mem_pestat] mean and std.dev: (544.23, 528.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3447)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 556, 3741)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10795)
[M::mem_pestat] mean and std.dev: (1508.30, 1751.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14322)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698224 sequences (100000130 bp) in 1.770 CPU sec, 1.775 real sec...
[M::mem_process_seqs] Processed 700688 reads in 179.053 CPU sec, 5.682 real sec
sorting block 131, #reads = 1074650 mem = 536878242 peak = 1094807552
[M::mem_process_seqs] Processed 698776 reads in 116.542 CPU sec, 3.691 real sec
sorting block 132, #reads = 1073385 mem = 536877676 peak = 1094807552
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (19, 282592, 29, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (256, 808, 2272)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6304)
[M::mem_pestat] mean and std.dev: (1385.16, 1579.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8320)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 232, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 699)
[M::mem_pestat] mean and std.dev: (258.81, 127.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 879)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (238, 364, 1539)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4141)
[M::mem_pestat] mean and std.dev: (746.21, 709.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5442)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 320, 605)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1427)
[M::mem_pestat] mean and std.dev: (377.88, 251.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1838)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698028 sequences (100000161 bp) in 2.309 CPU sec, 2.489 real sec...
[M::process] read 698346 sequences (100000118 bp) in 1.850 CPU sec, 1.848 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 283054, 20, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (301, 421, 696)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1486)
[M::mem_pestat] mean and std.dev: (451.08, 270.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1881)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 233, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 705)
[M::mem_pestat] mean and std.dev: (259.61, 128.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 887)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (115, 1100, 1465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4165)
[M::mem_pestat] mean and std.dev: (921.70, 792.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5515)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 379, 977)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2543)
[M::mem_pestat] mean and std.dev: (477.77, 465.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3326)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698176 reads in 175.598 CPU sec, 5.842 real sec
[M::mem_process_seqs] Processed 698224 reads in 116.648 CPU sec, 3.718 real sec
sorting block 133, #reads = 1073045 mem = 536877773 peak = 1094807552
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 282866, 16, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 350, 881)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2293)
[M::mem_pestat] mean and std.dev: (468.55, 426.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2999)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 234, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 705)
[M::mem_pestat] mean and std.dev: (260.50, 129.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 887)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (506, 545, 1009)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2015)
[M::mem_pestat] mean and std.dev: (509.31, 275.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2518)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (267, 346, 656)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1434)
[M::mem_pestat] mean and std.dev: (417.52, 280.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1823)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699262 sequences (100000241 bp) in 2.447 CPU sec, 2.564 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 283275, 33, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 308, 984)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2614)
[M::mem_pestat] mean and std.dev: (509.36, 513.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3429)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 233, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 707)
[M::mem_pestat] mean and std.dev: (260.01, 129.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 890)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (116, 305, 864)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2360)
[M::mem_pestat] mean and std.dev: (436.10, 535.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3108)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (365, 596, 1024)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2342)
[M::mem_pestat] mean and std.dev: (681.14, 472.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3001)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701002 sequences (100000124 bp) in 1.850 CPU sec, 1.859 real sec...
[M::mem_process_seqs] Processed 698028 reads in 166.659 CPU sec, 5.284 real sec
[M::mem_process_seqs] Processed 698346 reads in 108.489 CPU sec, 3.431 real sec
sorting block 134, #reads = 1074503 mem = 536882698 peak = 1094807552
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 283228, 11, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (325, 478, 797)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1741)
[M::mem_pestat] mean and std.dev: (527.30, 309.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2213)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 229, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 691)
[M::mem_pestat] mean and std.dev: (255.80, 126.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 869)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (318, 318, 2055)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5529)
[M::mem_pestat] mean and std.dev: (1225.00, 1248.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7266)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (283, 300, 597)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1225)
[M::mem_pestat] mean and std.dev: (328.67, 186.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1539)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700262 sequences (100000008 bp) in 2.724 CPU sec, 2.867 real sec...
[M::process] read 699506 sequences (100000016 bp) in 1.420 CPU sec, 1.422 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 283717, 23, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 249, 494)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1108)
[M::mem_pestat] mean and std.dev: (294.97, 193.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1415)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 223, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 667)
[M::mem_pestat] mean and std.dev: (249.42, 122.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 838)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (400, 958, 1137)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2611)
[M::mem_pestat] mean and std.dev: (690.79, 430.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3348)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (251, 550, 835)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2003)
[M::mem_pestat] mean and std.dev: (502.58, 340.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2587)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699262 reads in 164.902 CPU sec, 5.257 real sec
sorting block 135, #reads = 1075619 mem = 536880179 peak = 1094807552
[M::mem_process_seqs] Processed 701002 reads in 115.873 CPU sec, 3.707 real sec
sorting block 136, #reads = 1075389 mem = 536881371 peak = 1094807552
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 283548, 19, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 400, 1355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3689)
[M::mem_pestat] mean and std.dev: (875.95, 895.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4856)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 225, 327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 671)
[M::mem_pestat] mean and std.dev: (251.13, 123.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 843)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (838, 1106, 1773)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3643)
[M::mem_pestat] mean and std.dev: (960.88, 534.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4578)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 589, 965)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2447)
[M::mem_pestat] mean and std.dev: (659.20, 493.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3188)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699344 sequences (100000012 bp) in 2.156 CPU sec, 2.289 real sec...
[M::process] read 699628 sequences (100000236 bp) in 1.430 CPU sec, 1.424 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 283308, 35, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 384, 1364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3684)
[M::mem_pestat] mean and std.dev: (847.45, 969.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4844)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 229, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 687)
[M::mem_pestat] mean and std.dev: (255.20, 126.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 864)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (353, 572, 1219)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2951)
[M::mem_pestat] mean and std.dev: (749.94, 675.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3817)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 344, 395)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 753)
[M::mem_pestat] mean and std.dev: (324.57, 160.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 967)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700262 reads in 165.247 CPU sec, 5.268 real sec
[M::mem_process_seqs] Processed 699506 reads in 117.175 CPU sec, 3.741 real sec
sorting block 137, #reads = 1075075 mem = 536878437 peak = 1094807552
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 283036, 22, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 372, 771)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1911)
[M::mem_pestat] mean and std.dev: (504.89, 403.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2481)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 228, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 685)
[M::mem_pestat] mean and std.dev: (254.88, 126.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 861)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 884, 1240)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3288)
[M::mem_pestat] mean and std.dev: (863.50, 635.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4312)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 305, 1142)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3078)
[M::mem_pestat] mean and std.dev: (602.95, 712.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4046)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698692 sequences (100000085 bp) in 2.529 CPU sec, 2.655 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 282933, 32, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 362, 866)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2162)
[M::mem_pestat] mean and std.dev: (495.26, 426.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2810)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 229, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 688)
[M::mem_pestat] mean and std.dev: (255.59, 127.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 865)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (587, 796, 1667)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3827)
[M::mem_pestat] mean and std.dev: (980.30, 746.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4907)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 411, 1063)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2735)
[M::mem_pestat] mean and std.dev: (738.95, 671.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3571)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697848 sequences (100000201 bp) in 1.690 CPU sec, 1.684 real sec...
[M::mem_process_seqs] Processed 699344 reads in 167.329 CPU sec, 5.314 real sec
[M::mem_process_seqs] Processed 699628 reads in 109.071 CPU sec, 3.456 real sec
sorting block 138, #reads = 1074022 mem = 536879936 peak = 1094807552
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 282090, 18, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 324, 477)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1137)
[M::mem_pestat] mean and std.dev: (297.62, 201.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1467)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 231, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 695)
[M::mem_pestat] mean and std.dev: (257.44, 127.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 874)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (817, 2424, 3264)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8158)
[M::mem_pestat] mean and std.dev: (2124.00, 1224.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10605)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (269, 445, 987)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2423)
[M::mem_pestat] mean and std.dev: (609.41, 435.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3141)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697860 sequences (100000154 bp) in 2.503 CPU sec, 2.621 real sec...
[M::process] read 697158 sequences (100000129 bp) in 1.410 CPU sec, 1.418 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 282120, 32, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 454, 1378)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3790)
[M::mem_pestat] mean and std.dev: (666.42, 704.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4996)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 233, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 699)
[M::mem_pestat] mean and std.dev: (259.26, 128.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 879)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (444, 1301, 2553)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6771)
[M::mem_pestat] mean and std.dev: (1598.69, 1523.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8880)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 256, 921)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2441)
[M::mem_pestat] mean and std.dev: (538.25, 572.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3201)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698692 reads in 158.413 CPU sec, 5.032 real sec
sorting block 139, #reads = 1072329 mem = 536879553 peak = 1094807552
[M::mem_process_seqs] Processed 697848 reads in 102.306 CPU sec, 3.251 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 282290, 32, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 513, 1895)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5273)
[M::mem_pestat] mean and std.dev: (1282.34, 1539.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7439)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 232, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 696)
[M::mem_pestat] mean and std.dev: (258.94, 128.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 875)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 947, 1468)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4050)
[M::mem_pestat] mean and std.dev: (699.93, 538.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5341)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 414, 817)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2047)
[M::mem_pestat] mean and std.dev: (475.23, 420.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2662)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 140, #reads = 1072216 mem = 536879216 peak = 1094807552
[M::process] read 698548 sequences (100000254 bp) in 2.349 CPU sec, 2.453 real sec...
[M::process] read 698806 sequences (100000107 bp) in 1.540 CPU sec, 1.542 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 281419, 25, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (243, 485, 1601)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4317)
[M::mem_pestat] mean and std.dev: (662.64, 644.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5675)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 233, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 697)
[M::mem_pestat] mean and std.dev: (259.40, 127.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 876)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (500, 823, 1218)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2654)
[M::mem_pestat] mean and std.dev: (770.45, 413.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3372)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 331, 581)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1351)
[M::mem_pestat] mean and std.dev: (310.58, 155.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1736)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697860 reads in 159.211 CPU sec, 5.063 real sec
[M::mem_process_seqs] Processed 697158 reads in 104.973 CPU sec, 3.328 real sec
sorting block 141, #reads = 1071443 mem = 536880596 peak = 1094807552
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 281860, 25, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 327, 1742)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4860)
[M::mem_pestat] mean and std.dev: (842.87, 1038.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6419)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 229, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 683)
[M::mem_pestat] mean and std.dev: (255.17, 125.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 858)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (521, 1255, 3840)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10478)
[M::mem_pestat] mean and std.dev: (1922.72, 1892.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13797)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (239, 437, 857)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2093)
[M::mem_pestat] mean and std.dev: (583.80, 472.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2711)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698358 sequences (100000213 bp) in 2.223 CPU sec, 2.335 real sec...
[M::process] read 697954 sequences (100000055 bp) in 1.420 CPU sec, 1.418 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 282147, 40, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 515, 1709)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4751)
[M::mem_pestat] mean and std.dev: (1046.94, 1138.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6272)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 229, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 679)
[M::mem_pestat] mean and std.dev: (254.44, 124.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 853)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (296, 703, 1373)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3527)
[M::mem_pestat] mean and std.dev: (795.73, 706.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4604)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 354, 638)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1474)
[M::mem_pestat] mean and std.dev: (359.39, 214.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1892)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698548 reads in 166.600 CPU sec, 5.305 real sec
[M::mem_process_seqs] Processed 698806 reads in 109.287 CPU sec, 3.480 real sec
sorting block 142, #reads = 1068425 mem = 536878559 peak = 1094807552
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 282046, 18, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 269, 534)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1216)
[M::mem_pestat] mean and std.dev: (285.26, 166.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1557)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 229, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 683)
[M::mem_pestat] mean and std.dev: (255.17, 125.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 858)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (357, 938, 1659)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4263)
[M::mem_pestat] mean and std.dev: (1317.50, 1224.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6215)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 289, 1007)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2609)
[M::mem_pestat] mean and std.dev: (476.61, 418.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3410)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697826 sequences (100000060 bp) in 2.097 CPU sec, 2.206 real sec...
[M::process] read 698302 sequences (100000157 bp) in 1.420 CPU sec, 1.426 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 281668, 25, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 429, 1829)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5069)
[M::mem_pestat] mean and std.dev: (821.69, 821.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6689)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 230, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 684)
[M::mem_pestat] mean and std.dev: (256.73, 126.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 859)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (250, 852, 2061)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5683)
[M::mem_pestat] mean and std.dev: (943.96, 782.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7494)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 266, 478)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1074)
[M::mem_pestat] mean and std.dev: (269.27, 189.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1372)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698358 reads in 164.242 CPU sec, 5.288 real sec
sorting block 143, #reads = 1066504 mem = 536879862 peak = 1094807552
[M::mem_process_seqs] Processed 697954 reads in 103.331 CPU sec, 3.291 real sec
sorting block 144, #reads = 1069834 mem = 536880808 peak = 1094807552
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 281461, 17, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 320, 1580)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4358)
[M::mem_pestat] mean and std.dev: (962.80, 1087.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5747)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 230, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 684)
[M::mem_pestat] mean and std.dev: (256.31, 126.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 859)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (505, 551, 1008)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2014)
[M::mem_pestat] mean and std.dev: (703.69, 408.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2517)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 261, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 751)
[M::mem_pestat] mean and std.dev: (224.84, 96.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 945)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698318 sequences (100000236 bp) in 2.175 CPU sec, 2.265 real sec...
[M::process] read 697802 sequences (100000006 bp) in 1.420 CPU sec, 1.421 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 282088, 27, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 465, 1254)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3408)
[M::mem_pestat] mean and std.dev: (622.28, 586.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4485)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 228, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 674)
[M::mem_pestat] mean and std.dev: (254.23, 124.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 846)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (306, 618, 1334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3390)
[M::mem_pestat] mean and std.dev: (948.70, 813.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4418)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 320, 1015)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2735)
[M::mem_pestat] mean and std.dev: (497.24, 535.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3595)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697826 reads in 164.200 CPU sec, 5.320 real sec
[M::mem_process_seqs] Processed 698302 reads in 104.923 CPU sec, 3.337 real sec
sorting block 145, #reads = 1069541 mem = 536880333 peak = 1094807552
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 282265, 20, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 255, 839)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2207)
[M::mem_pestat] mean and std.dev: (421.49, 397.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2891)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 228, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 680)
[M::mem_pestat] mean and std.dev: (254.93, 125.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 854)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (532, 921, 1808)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4360)
[M::mem_pestat] mean and std.dev: (820.71, 582.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5636)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 308, 413)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 823)
[M::mem_pestat] mean and std.dev: (277.33, 122.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1028)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698590 sequences (100000126 bp) in 2.029 CPU sec, 2.118 real sec...
[M::process] read 697946 sequences (100000120 bp) in 1.460 CPU sec, 1.461 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 281770, 15, 19)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (254, 443, 907)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2213)
[M::mem_pestat] mean and std.dev: (673.98, 565.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2936)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 229, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 680)
[M::mem_pestat] mean and std.dev: (255.20, 125.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 854)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (477, 519, 1596)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3834)
[M::mem_pestat] mean and std.dev: (701.00, 672.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4953)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (258, 447, 8720)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 25644)
[M::mem_pestat] mean and std.dev: (2596.47, 3665.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 34106)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698318 reads in 163.951 CPU sec, 5.319 real sec
[M::mem_process_seqs] Processed 697802 reads in 104.893 CPU sec, 3.340 real sec
sorting block 146, #reads = 1068237 mem = 536882944 peak = 1094807552
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 282234, 20, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (277, 579, 973)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2365)
[M::mem_pestat] mean and std.dev: (637.14, 442.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3061)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 228, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 670)
[M::mem_pestat] mean and std.dev: (252.99, 124.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 841)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (394, 834, 2293)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6091)
[M::mem_pestat] mean and std.dev: (1519.20, 1623.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8012)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (252, 407, 1291)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3369)
[M::mem_pestat] mean and std.dev: (741.14, 785.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4408)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699866 sequences (100000228 bp) in 2.299 CPU sec, 2.397 real sec...
[M::process] read 706992 sequences (100000142 bp) in 1.480 CPU sec, 1.477 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 282032, 33, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 242, 978)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2572)
[M::mem_pestat] mean and std.dev: (537.40, 610.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3369)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 229, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 677)
[M::mem_pestat] mean and std.dev: (254.91, 124.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 850)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 760, 1700)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4738)
[M::mem_pestat] mean and std.dev: (865.69, 839.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6257)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 286, 587)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1377)
[M::mem_pestat] mean and std.dev: (348.88, 243.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1772)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698590 reads in 172.365 CPU sec, 5.489 real sec
sorting block 147, #reads = 1068067 mem = 536882157 peak = 1094807552
[M::mem_process_seqs] Processed 697946 reads in 117.168 CPU sec, 3.727 real sec
sorting block 148, #reads = 1064755 mem = 536881135 peak = 1094807552
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 282732, 27, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 369, 632)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1552)
[M::mem_pestat] mean and std.dev: (451.05, 349.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2012)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 225, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 665)
[M::mem_pestat] mean and std.dev: (250.29, 122.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 835)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (329, 563, 902)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2048)
[M::mem_pestat] mean and std.dev: (552.08, 417.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2621)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (230, 720, 1311)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3473)
[M::mem_pestat] mean and std.dev: (824.89, 804.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4554)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704484 sequences (100000142 bp) in 2.809 CPU sec, 2.914 real sec...
[M::process] read 702758 sequences (100000204 bp) in 1.950 CPU sec, 1.946 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 285241, 20, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (251, 407, 1323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3467)
[M::mem_pestat] mean and std.dev: (786.82, 831.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4539)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 209, 302)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 614)
[M::mem_pestat] mean and std.dev: (234.08, 114.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 770)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (371, 894, 2618)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7112)
[M::mem_pestat] mean and std.dev: (1337.65, 1110.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9359)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 250, 383)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 789)
[M::mem_pestat] mean and std.dev: (232.76, 97.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 992)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699866 reads in 186.434 CPU sec, 5.919 real sec
[M::mem_process_seqs] Processed 706992 reads in 128.392 CPU sec, 4.096 real sec
sorting block 149, #reads = 1061634 mem = 536883250 peak = 1094807552
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 284471, 11, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (228, 502, 965)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2439)
[M::mem_pestat] mean and std.dev: (528.12, 480.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3176)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 215, 313)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 639)
[M::mem_pestat] mean and std.dev: (240.92, 119.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 802)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (726, 1185, 4470)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 11958)
[M::mem_pestat] mean and std.dev: (2328.09, 2144.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 15702)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 408, 716)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1738)
[M::mem_pestat] mean and std.dev: (453.37, 396.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2249)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701994 sequences (100000145 bp) in 2.179 CPU sec, 2.255 real sec...
[M::process] read 701228 sequences (100000083 bp) in 1.460 CPU sec, 1.456 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 284230, 20, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 257, 508)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1184)
[M::mem_pestat] mean and std.dev: (339.42, 257.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1522)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 219, 320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 656)
[M::mem_pestat] mean and std.dev: (246.14, 122.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 824)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 588, 1220)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3294)
[M::mem_pestat] mean and std.dev: (611.63, 508.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4331)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 863, 1420)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3832)
[M::mem_pestat] mean and std.dev: (888.98, 753.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5038)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704484 reads in 171.398 CPU sec, 5.463 real sec
[M::mem_process_seqs] Processed 702758 reads in 112.033 CPU sec, 3.570 real sec
sorting block 150, #reads = 1068587 mem = 536878506 peak = 1094807552
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 283283, 34, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 324, 1366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3752)
[M::mem_pestat] mean and std.dev: (592.36, 640.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4945)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 221, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 669)
[M::mem_pestat] mean and std.dev: (248.99, 124.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 841)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (419, 914, 1824)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4634)
[M::mem_pestat] mean and std.dev: (1218.62, 1096.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6039)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (315, 428, 1669)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4377)
[M::mem_pestat] mean and std.dev: (802.93, 782.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5731)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700564 sequences (100000187 bp) in 2.382 CPU sec, 2.489 real sec...
[M::process] read 699344 sequences (100000127 bp) in 1.550 CPU sec, 1.551 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 283444, 13, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 467, 1215)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3183)
[M::mem_pestat] mean and std.dev: (607.05, 589.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4167)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 225, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 679)
[M::mem_pestat] mean and std.dev: (252.13, 125.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 854)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (710, 891, 1482)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3026)
[M::mem_pestat] mean and std.dev: (978.31, 411.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3798)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 417, 1249)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3395)
[M::mem_pestat] mean and std.dev: (701.55, 815.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4468)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701994 reads in 172.820 CPU sec, 5.513 real sec
sorting block 151, #reads = 1070920 mem = 536884997 peak = 1094807552
[M::mem_process_seqs] Processed 701228 reads in 112.712 CPU sec, 3.690 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 283519, 24, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (232, 401, 815)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1981)
[M::mem_pestat] mean and std.dev: (554.08, 422.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2564)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 225, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 677)
[M::mem_pestat] mean and std.dev: (252.17, 125.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 851)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (320, 625, 1685)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4415)
[M::mem_pestat] mean and std.dev: (744.90, 599.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5780)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (243, 924, 2168)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6018)
[M::mem_pestat] mean and std.dev: (1266.54, 1178.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7943)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699158 sequences (100000154 bp) in 2.277 CPU sec, 2.382 real sec...
[M::process] read 698528 sequences (100000250 bp) in 1.510 CPU sec, 1.510 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 283011, 17, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 253, 1089)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2933)
[M::mem_pestat] mean and std.dev: (484.32, 572.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3855)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 229, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 691)
[M::mem_pestat] mean and std.dev: (256.32, 127.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 869)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (330, 794, 3254)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9102)
[M::mem_pestat] mean and std.dev: (1742.41, 1965.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12026)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (230, 485, 1511)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4073)
[M::mem_pestat] mean and std.dev: (829.13, 882.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5354)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700564 reads in 177.072 CPU sec, 5.743 real sec
sorting block 152, #reads = 1069108 mem = 536879690 peak = 1094807552
[M::mem_process_seqs] Processed 699344 reads in 113.541 CPU sec, 3.612 real sec
sorting block 153, #reads = 1071197 mem = 536882895 peak = 1094807552
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 282842, 26, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 566, 2747)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7809)
[M::mem_pestat] mean and std.dev: (1924.42, 2445.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11706)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 230, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 697)
[M::mem_pestat] mean and std.dev: (257.09, 127.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 877)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (113, 400, 980)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2714)
[M::mem_pestat] mean and std.dev: (633.23, 584.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3581)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (245, 438, 1174)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3032)
[M::mem_pestat] mean and std.dev: (607.08, 512.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3961)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698362 sequences (100000074 bp) in 2.347 CPU sec, 2.461 real sec...
[M::process] read 699490 sequences (100000236 bp) in 1.420 CPU sec, 1.419 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 282677, 22, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 305, 1005)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2683)
[M::mem_pestat] mean and std.dev: (541.78, 536.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3522)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 232, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 710)
[M::mem_pestat] mean and std.dev: (260.33, 130.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 894)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (322, 770, 1661)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4339)
[M::mem_pestat] mean and std.dev: (1016.48, 881.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5678)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 279, 1248)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3302)
[M::mem_pestat] mean and std.dev: (619.76, 696.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4329)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699158 reads in 168.157 CPU sec, 5.351 real sec
[M::mem_process_seqs] Processed 698528 reads in 107.765 CPU sec, 3.448 real sec
sorting block 154, #reads = 1068100 mem = 536883035 peak = 1094807552
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 283188, 29, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (223, 360, 2923)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8323)
[M::mem_pestat] mean and std.dev: (824.69, 1001.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11023)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 232, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 707)
[M::mem_pestat] mean and std.dev: (259.96, 129.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 890)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (226, 630, 1254)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3310)
[M::mem_pestat] mean and std.dev: (718.71, 560.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4338)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 558, 765)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1935)
[M::mem_pestat] mean and std.dev: (494.12, 394.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2520)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698816 sequences (100000057 bp) in 2.216 CPU sec, 2.338 real sec...
[M::process] read 698048 sequences (100000128 bp) in 1.410 CPU sec, 1.403 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 282983, 27, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 294, 845)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2115)
[M::mem_pestat] mean and std.dev: (442.77, 362.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2750)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 228, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 687)
[M::mem_pestat] mean and std.dev: (254.68, 125.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 864)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (493, 747, 1234)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2716)
[M::mem_pestat] mean and std.dev: (751.04, 535.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3457)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 464, 966)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2470)
[M::mem_pestat] mean and std.dev: (481.96, 408.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3222)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698362 reads in 164.050 CPU sec, 5.244 real sec
[M::mem_process_seqs] Processed 699490 reads in 104.155 CPU sec, 3.317 real sec
sorting block 155, #reads = 1071189 mem = 536878392 peak = 1094807552
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 282286, 25, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 392, 797)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1989)
[M::mem_pestat] mean and std.dev: (538.09, 517.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2609)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 229, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 685)
[M::mem_pestat] mean and std.dev: (254.93, 124.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 861)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 306, 1165)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3055)
[M::mem_pestat] mean and std.dev: (545.04, 636.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4000)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 502, 1308)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3492)
[M::mem_pestat] mean and std.dev: (618.51, 541.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4584)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697534 sequences (100000020 bp) in 2.261 CPU sec, 2.377 real sec...
[M::process] read 696858 sequences (100000195 bp) in 1.440 CPU sec, 1.437 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 281752, 24, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 270, 680)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1672)
[M::mem_pestat] mean and std.dev: (320.66, 276.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2168)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 232, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 696)
[M::mem_pestat] mean and std.dev: (258.44, 127.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 875)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (45, 334, 682)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1956)
[M::mem_pestat] mean and std.dev: (322.32, 342.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2593)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 297, 998)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2612)
[M::mem_pestat] mean and std.dev: (539.53, 612.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3419)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698816 reads in 158.352 CPU sec, 5.036 real sec
sorting block 156, #reads = 1071177 mem = 536878088 peak = 1094807552
[M::mem_process_seqs] Processed 698048 reads in 103.129 CPU sec, 3.278 real sec
sorting block 157, #reads = 1069741 mem = 536880818 peak = 1118101504
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 282234, 19, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 384, 1321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3527)
[M::mem_pestat] mean and std.dev: (598.38, 588.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4630)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 234, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 697)
[M::mem_pestat] mean and std.dev: (259.22, 127.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 876)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (466, 898, 2186)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5626)
[M::mem_pestat] mean and std.dev: (1412.89, 1295.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7346)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 267, 534)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1190)
[M::mem_pestat] mean and std.dev: (295.65, 188.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1518)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697468 sequences (100000009 bp) in 2.205 CPU sec, 2.295 real sec...
[M::process] read 696604 sequences (100000212 bp) in 1.410 CPU sec, 1.408 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 281665, 32, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (227, 442, 815)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1991)
[M::mem_pestat] mean and std.dev: (545.69, 474.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2579)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 235, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 698)
[M::mem_pestat] mean and std.dev: (260.24, 126.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 877)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (370, 409, 1466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3658)
[M::mem_pestat] mean and std.dev: (650.34, 483.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4754)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 333, 2820)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8038)
[M::mem_pestat] mean and std.dev: (1094.38, 1462.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10647)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697534 reads in 158.643 CPU sec, 5.048 real sec
[M::mem_process_seqs] Processed 696858 reads in 103.522 CPU sec, 3.296 real sec
sorting block 158, #reads = 1070614 mem = 536880961 peak = 1118101504
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 281404, 22, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 358, 1319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3659)
[M::mem_pestat] mean and std.dev: (561.65, 575.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4829)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 234, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 691)
[M::mem_pestat] mean and std.dev: (258.45, 125.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 868)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 475, 805)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2083)
[M::mem_pestat] mean and std.dev: (474.67, 455.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2722)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 371, 669)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1587)
[M::mem_pestat] mean and std.dev: (448.79, 361.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2046)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696242 sequences (100000180 bp) in 2.141 CPU sec, 2.228 real sec...
[M::process] read 696370 sequences (100000074 bp) in 1.430 CPU sec, 1.429 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 281415, 16, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 322, 924)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2466)
[M::mem_pestat] mean and std.dev: (531.33, 529.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3237)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 234, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 689)
[M::mem_pestat] mean and std.dev: (258.64, 124.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 865)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (451, 743, 2232)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5794)
[M::mem_pestat] mean and std.dev: (1040.06, 815.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7575)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (239, 337, 817)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1973)
[M::mem_pestat] mean and std.dev: (483.08, 430.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2551)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697468 reads in 164.367 CPU sec, 5.233 real sec
sorting block 159, #reads = 1068707 mem = 536878980 peak = 1118101504
[M::mem_process_seqs] Processed 696604 reads in 106.765 CPU sec, 3.401 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 281109, 27, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 357, 812)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2038)
[M::mem_pestat] mean and std.dev: (354.34, 245.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2651)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 236, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 690)
[M::mem_pestat] mean and std.dev: (259.65, 124.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 866)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 297, 1493)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4119)
[M::mem_pestat] mean and std.dev: (918.23, 1131.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5444)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (235, 528, 1391)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3703)
[M::mem_pestat] mean and std.dev: (691.33, 679.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4859)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696510 sequences (100000016 bp) in 2.343 CPU sec, 2.421 real sec...
[M::process] read 695856 sequences (100000102 bp) in 1.490 CPU sec, 1.496 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 281605, 34, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 347, 1264)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3454)
[M::mem_pestat] mean and std.dev: (773.35, 848.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4549)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 236, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 684)
[M::mem_pestat] mean and std.dev: (258.69, 124.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 858)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (547, 1080, 1905)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4621)
[M::mem_pestat] mean and std.dev: (1365.18, 1105.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5979)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (262, 408, 1074)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2698)
[M::mem_pestat] mean and std.dev: (606.80, 576.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3510)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696242 reads in 164.847 CPU sec, 5.524 real sec
sorting block 160, #reads = 1066651 mem = 536880013 peak = 1118101504
[M::mem_process_seqs] Processed 696370 reads in 106.727 CPU sec, 3.398 real sec
sorting block 161, #reads = 1068507 mem = 536879717 peak = 1118101504
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 281220, 24, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 304, 492)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1096)
[M::mem_pestat] mean and std.dev: (320.43, 218.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1398)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 235, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 686)
[M::mem_pestat] mean and std.dev: (258.49, 124.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 861)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (238, 658, 934)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2326)
[M::mem_pestat] mean and std.dev: (595.90, 512.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3022)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 410, 869)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2243)
[M::mem_pestat] mean and std.dev: (510.68, 452.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2930)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695826 sequences (100000260 bp) in 2.306 CPU sec, 2.395 real sec...
[M::process] read 695792 sequences (100000195 bp) in 1.410 CPU sec, 1.413 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 280894, 20, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (255, 365, 887)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2151)
[M::mem_pestat] mean and std.dev: (481.98, 425.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2783)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 236, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 687)
[M::mem_pestat] mean and std.dev: (259.22, 124.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 862)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 289, 1376)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3740)
[M::mem_pestat] mean and std.dev: (620.89, 751.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4922)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (139, 339, 787)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2083)
[M::mem_pestat] mean and std.dev: (441.57, 421.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2731)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696510 reads in 156.803 CPU sec, 4.990 real sec
[M::mem_process_seqs] Processed 695856 reads in 102.247 CPU sec, 3.244 real sec
sorting block 162, #reads = 1069884 mem = 536877343 peak = 1118101504
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 280897, 19, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 345, 1834)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5186)
[M::mem_pestat] mean and std.dev: (1041.97, 1416.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6862)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 237, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 687)
[M::mem_pestat] mean and std.dev: (258.96, 123.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 862)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (336, 880, 3146)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8766)
[M::mem_pestat] mean and std.dev: (2247.84, 2705.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13071)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 315, 832)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2132)
[M::mem_pestat] mean and std.dev: (490.25, 500.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2782)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696142 sequences (100000292 bp) in 2.194 CPU sec, 2.264 real sec...
[M::process] read 695714 sequences (100000046 bp) in 1.400 CPU sec, 1.405 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 280990, 24, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (234, 345, 911)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2265)
[M::mem_pestat] mean and std.dev: (426.73, 368.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2942)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 237, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 687)
[M::mem_pestat] mean and std.dev: (259.37, 123.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 862)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (340, 620, 1688)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4384)
[M::mem_pestat] mean and std.dev: (1089.04, 1348.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6484)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 282, 854)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2172)
[M::mem_pestat] mean and std.dev: (501.57, 422.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2831)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695826 reads in 156.275 CPU sec, 4.974 real sec
[M::mem_process_seqs] Processed 695792 reads in 101.697 CPU sec, 3.233 real sec
sorting block 163, #reads = 1069615 mem = 536887613 peak = 1118101504
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 280986, 38, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (252, 419, 1105)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2811)
[M::mem_pestat] mean and std.dev: (638.40, 619.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3664)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 234, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 680)
[M::mem_pestat] mean and std.dev: (256.94, 123.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 853)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 693, 1395)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3873)
[M::mem_pestat] mean and std.dev: (925.05, 854.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5112)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 275, 1065)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2805)
[M::mem_pestat] mean and std.dev: (460.07, 405.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3675)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695776 sequences (100000134 bp) in 2.123 CPU sec, 2.217 real sec...
[M::process] read 695426 sequences (100000230 bp) in 1.390 CPU sec, 1.399 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 280830, 28, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 281, 1128)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3056)
[M::mem_pestat] mean and std.dev: (488.38, 549.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4020)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 235, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 684)
[M::mem_pestat] mean and std.dev: (258.30, 123.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 858)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (100, 730, 1349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3847)
[M::mem_pestat] mean and std.dev: (742.43, 698.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5096)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 229, 572)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1364)
[M::mem_pestat] mean and std.dev: (331.42, 293.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1760)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696142 reads in 155.780 CPU sec, 4.973 real sec
sorting block 164, #reads = 1069762 mem = 536888067 peak = 1118101504
[M::mem_process_seqs] Processed 695714 reads in 102.028 CPU sec, 3.261 real sec
sorting block 165, #reads = 1070384 mem = 536879924 peak = 1118101504
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 281025, 26, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (234, 406, 1266)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3330)
[M::mem_pestat] mean and std.dev: (872.30, 863.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4362)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 237, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 687)
[M::mem_pestat] mean and std.dev: (259.29, 124.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 862)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 658, 704)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1818)
[M::mem_pestat] mean and std.dev: (455.87, 351.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2375)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 567, 1933)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5411)
[M::mem_pestat] mean and std.dev: (1052.29, 1087.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7150)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695548 sequences (100000098 bp) in 2.192 CPU sec, 2.285 real sec...
[M::process] read 695784 sequences (100000064 bp) in 1.420 CPU sec, 1.418 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 280981, 29, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 292, 607)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1481)
[M::mem_pestat] mean and std.dev: (387.16, 325.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1918)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 237, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 688)
[M::mem_pestat] mean and std.dev: (259.84, 124.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 863)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (118, 466, 2189)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6331)
[M::mem_pestat] mean and std.dev: (998.30, 1198.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8402)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (143, 311, 784)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2066)
[M::mem_pestat] mean and std.dev: (455.76, 419.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2707)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695776 reads in 153.461 CPU sec, 4.886 real sec
[M::mem_process_seqs] Processed 695426 reads in 108.599 CPU sec, 3.469 real sec
sorting block 166, #reads = 1071066 mem = 536883336 peak = 1118101504
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 281590, 27, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (298, 746, 1227)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3085)
[M::mem_pestat] mean and std.dev: (820.53, 775.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4014)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 238, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 688)
[M::mem_pestat] mean and std.dev: (260.32, 124.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 863)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (758, 1255, 1899)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4181)
[M::mem_pestat] mean and std.dev: (1435.77, 1031.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5562)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (258, 485, 1626)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4362)
[M::mem_pestat] mean and std.dev: (772.73, 668.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5730)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695520 sequences (100000252 bp) in 2.148 CPU sec, 2.228 real sec...
[M::process] read 695910 sequences (100000182 bp) in 1.420 CPU sec, 1.421 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 281300, 37, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 364, 763)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1915)
[M::mem_pestat] mean and std.dev: (457.82, 314.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2491)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 237, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 690)
[M::mem_pestat] mean and std.dev: (259.98, 124.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 866)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 305, 493)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1145)
[M::mem_pestat] mean and std.dev: (305.28, 224.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1471)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 386, 3545)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10197)
[M::mem_pestat] mean and std.dev: (1835.14, 2486.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13523)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695548 reads in 152.122 CPU sec, 4.844 real sec
[M::mem_process_seqs] Processed 695784 reads in 99.246 CPU sec, 3.149 real sec
sorting block 167, #reads = 1070326 mem = 536877933 peak = 1118101504
[M::process] read 326284 sequences (46794340 bp) in 1.190 CPU sec, 1.222 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 280846, 20, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (328, 830, 2753)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7603)
[M::mem_pestat] mean and std.dev: (1359.25, 1386.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10028)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 237, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 694)
[M::mem_pestat] mean and std.dev: (260.85, 125.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 871)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (421, 780, 1219)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2815)
[M::mem_pestat] mean and std.dev: (822.50, 654.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3613)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (237, 347, 1089)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2793)
[M::mem_pestat] mean and std.dev: (618.00, 639.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3645)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 131791, 10, 12)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (280, 700, 1008)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2464)
[M::mem_pestat] mean and std.dev: (647.26, 469.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3192)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 232, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 679)
[M::mem_pestat] mean and std.dev: (256.14, 123.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 852)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (503, 1175, 1329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2981)
[M::mem_pestat] mean and std.dev: (878.40, 605.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3807)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 308, 1706)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4716)
[M::mem_pestat] mean and std.dev: (608.09, 644.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6221)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695520 reads in 120.826 CPU sec, 3.902 real sec
sorting block 168, #reads = 1072435 mem = 536881000 peak = 1118101504
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 281553, 20, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (238, 380, 684)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1576)
[M::mem_pestat] mean and std.dev: (422.11, 326.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2022)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 237, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 693)
[M::mem_pestat] mean and std.dev: (260.45, 125.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 870)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (433, 1073, 1697)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4225)
[M::mem_pestat] mean and std.dev: (1148.95, 864.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5489)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 315, 662)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1624)
[M::mem_pestat] mean and std.dev: (427.58, 404.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2105)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 326284 reads in 128.357 CPU sec, 4.148 real sec
[M::mem_process_seqs] Processed 695910 reads in 144.789 CPU sec, 4.690 real sec
sorting block 169, #reads = 1068420 mem = 536878323 peak = 1118101504
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000a06d1
  features: 1f8bfbff fffab20b
  extended: f1bf27eb 1b407f7e
  amd bits: 2c100800 00000121
     brand: Intel(R) Xeon(R) 6975P-C
threads: 31
algo: bwa-mem
license: sentieon:klib=31
reads: 181087370
overall: 70685212672 mem 28585.706 user 541.048 sys 965.962 real
[main] Version: 0.7.17-r1188
[main] CMD: /opt/conda/share/sentieon-202308.03-3/libexec/bwa mem -K 100000000 -Y -R @RG\tID:A23MHWWLT4.1029_HTI-T1-TDNA-1_A23MHWWLT4_1.L001\tPU:L001\tSM:1029_HTI-T1-TDNA-1_A23MHWWLT4_1\tLB:1029_HTI-T1-TDNA-1_A23MHWWLT4_1\tDS:s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta\tPL:ILLUMINA -t 31 ./BWAIndex/Homo_sapiens_assembly38.fasta.64 1029_HTI-T1-TDNA-1_A23MHWWLT4_1_R1.fastq.gz 1029_HTI-T1-TDNA-1_A23MHWWLT4_1_R2.fastq.gz
[main] Real time: 966.002 sec; CPU: 29126.760 sec
sorting block 170, #reads = 396782 mem = 198838031 peak = 1118101504
uniq header count 1
merging 171 blocks
sw version: sentieon-genomics-202308.03
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000a06d1
  features: 1f8bfbff fffab20b
  extended: f1bf27eb 1b407f7e
  amd bits: 2c100800 00000121
     brand: Intel(R) Xeon(R) 6975P-C
threads: 31 max 192
algo: util-sort
license: sentieon:util=1
output file size: 9991430352
output reads: 182516648
bam_mem_sort: 171 calls 98.851 user 2.456 sys 102.152 real
bam_write: 171 calls 56.434 user 3.125 sys 71.357 real
execute: 1 calls 40.220 user 2.673 sys 1019.998 real
merge_files: 1 calls 40.209 user 2.636 sys 53.539 real
parse_chunk: 2726 calls 117.715 user 29.505 sys 153.869 real
read_chunk: 7375 calls 58.949 user 52.897 sys 907.016 real
sort_block: 1 calls 39.757 user 51.967 sys 879.808 real
write_chunk: 4647 calls 39.770 user 2.261 sys 52.372 real
overall: 3722162176 mem 2182.476 user 117.296 sys 1020.020 real
ls: cannot access '*.cram': No such file or directory