Downloading: s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/a3/ca160a43c950f4a1af4ec76c42dd54/.command.sh
  Downloading: s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta.fai
  Downloading: s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/BWAIndex
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/a5/2751ca032ca8394b2ff17a119049a5/1136_3WJ-T1-TDNA-1_A23MHWWLT4_1/1136_3WJ-T1-TDNA-1_A23MHWWLT4_1_R2.fastq.gz
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/a5/2751ca032ca8394b2ff17a119049a5/1136_3WJ-T1-TDNA-1_A23MHWWLT4_1/1136_3WJ-T1-TDNA-1_A23MHWWLT4_1_R1.fastq.gz
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/a3/ca160a43c950f4a1af4ec76c42dd54/.command.run
==> STAGING COMPLETE (7 inputs)

This software is licensed to bgold@natera.com by Sentieon Inc.
cmdline: /opt/conda/share/sentieon-202308.03-3/libexec/util sort -r Homo_sapiens_assembly38.fasta -t 31 -o 1136_3WJ-T1-TDNA-1_A23MHWWLT4_1.bam --sam2bam -
This software is licensed to bgold@natera.com by Sentieon Inc.
version: sentieon-genomics-202308.03
[M::bwa_idx_load_from_disk] read 3171 ALT contigs
[M::main_mem] bwa index loaded in 2161.521 CPU sec, 101.159 real sec
[M::process] read 709672 sequences (100000138 bp) in 1.564 CPU sec, 1.574 real sec...
[M::process] read 708112 sequences (100000129 bp) in 1.827 CPU sec, 2.103 real sec...
[M::process] read 706836 sequences (100000065 bp) in 1.857 CPU sec, 2.054 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 282404, 45, 74)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 455, 1252)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3352)
[M::mem_pestat] mean and std.dev: (779.88, 696.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4402)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 214, 310)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 638)
[M::mem_pestat] mean and std.dev: (237.77, 117.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 802)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (291, 788, 1497)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3909)
[M::mem_pestat] mean and std.dev: (946.48, 854.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5115)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (258, 558, 903)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2193)
[M::mem_pestat] mean and std.dev: (621.09, 480.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2838)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706236 sequences (100000067 bp) in 1.833 CPU sec, 2.068 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 281612, 49, 92)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (223, 449, 1932)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5350)
[M::mem_pestat] mean and std.dev: (615.45, 718.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7059)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 217, 317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 655)
[M::mem_pestat] mean and std.dev: (241.91, 120.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 824)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (77, 529, 1930)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5636)
[M::mem_pestat] mean and std.dev: (886.18, 843.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7489)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 457, 1498)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4102)
[M::mem_pestat] mean and std.dev: (897.92, 1038.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5404)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (91, 281702, 51, 77)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 499, 1681)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4685)
[M::mem_pestat] mean and std.dev: (822.22, 861.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6187)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 220, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 668)
[M::mem_pestat] mean and std.dev: (245.08, 122.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 841)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 586, 1316)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3536)
[M::mem_pestat] mean and std.dev: (841.00, 789.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4646)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 301, 702)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1764)
[M::mem_pestat] mean and std.dev: (406.03, 335.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2295)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 709672 reads in 355.465 CPU sec, 13.218 real sec
[M::mem_process_seqs] Processed 708112 reads in 270.429 CPU sec, 9.954 real sec
[M::mem_process_seqs] Processed 706836 reads in 303.774 CPU sec, 11.121 real sec
sorting block 0, #reads = 1071514 mem = 536878437 peak = 574799872
[M::process] read 705178 sequences (100000146 bp) in 2.369 CPU sec, 2.516 real sec...
[M::process] read 705014 sequences (100000015 bp) in 2.524 CPU sec, 2.703 real sec...
sorting block 1, #reads = 1071899 mem = 536882227 peak = 847974400
[M::process] read 706548 sequences (100000291 bp) in 1.873 CPU sec, 1.906 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 280917, 60, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (235, 506, 1182)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3076)
[M::mem_pestat] mean and std.dev: (655.59, 524.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4023)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 225, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 683)
[M::mem_pestat] mean and std.dev: (250.08, 124.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 860)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (381, 756, 1476)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3666)
[M::mem_pestat] mean and std.dev: (766.41, 650.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4761)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 466, 761)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1879)
[M::mem_pestat] mean and std.dev: (440.67, 314.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2438)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 705178 reads in 138.754 CPU sec, 4.612 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (94, 280966, 71, 73)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (261, 459, 818)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1932)
[M::mem_pestat] mean and std.dev: (554.28, 413.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2489)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 222, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 672)
[M::mem_pestat] mean and std.dev: (246.82, 123.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 846)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 792, 2527)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7221)
[M::mem_pestat] mean and std.dev: (1637.56, 1920.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9568)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 326, 1076)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2782)
[M::mem_pestat] mean and std.dev: (671.75, 671.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3635)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (79, 281518, 42, 94)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 509, 962)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2438)
[M::mem_pestat] mean and std.dev: (579.42, 444.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3176)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 226, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 689)
[M::mem_pestat] mean and std.dev: (251.37, 126.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 868)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (135, 561, 1713)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4869)
[M::mem_pestat] mean and std.dev: (1054.40, 1171.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6447)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 404, 813)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1989)
[M::mem_pestat] mean and std.dev: (446.18, 371.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2577)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705824 sequences (100000014 bp) in 2.383 CPU sec, 2.407 real sec...
[M::mem_process_seqs] Processed 706236 reads in 379.836 CPU sec, 12.586 real sec
sorting block 2, #reads = 1070257 mem = 536879161 peak = 847974400
[M::mem_process_seqs] Processed 705014 reads in 202.696 CPU sec, 6.767 real sec
[M::process] read 705226 sequences (100000189 bp) in 2.450 CPU sec, 2.720 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 281229, 40, 86)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 373, 751)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1867)
[M::mem_pestat] mean and std.dev: (460.66, 370.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2425)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 220, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 668)
[M::mem_pestat] mean and std.dev: (245.74, 123.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 841)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (247, 490, 1776)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4834)
[M::mem_pestat] mean and std.dev: (1022.38, 1134.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6363)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (248, 397, 935)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2309)
[M::mem_pestat] mean and std.dev: (580.63, 498.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2996)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704764 sequences (100000178 bp) in 2.103 CPU sec, 2.122 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (77, 280897, 44, 89)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 377, 984)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2528)
[M::mem_pestat] mean and std.dev: (524.26, 475.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3300)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 222, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 672)
[M::mem_pestat] mean and std.dev: (247.48, 123.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 846)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (520, 945, 3415)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9205)
[M::mem_pestat] mean and std.dev: (2247.50, 2807.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13477)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (259, 447, 1403)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3691)
[M::mem_pestat] mean and std.dev: (751.75, 706.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4835)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 706548 reads in 248.662 CPU sec, 8.395 real sec
sorting block 3, #reads = 1072104 mem = 536876546 peak = 847974400
[M::mem_process_seqs] Processed 705824 reads in 171.318 CPU sec, 5.588 real sec
sorting block 4, #reads = 1070844 mem = 536879219 peak = 927264768
[M::process] read 704246 sequences (100000193 bp) in 2.705 CPU sec, 2.836 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (76, 280403, 67, 104)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 318, 1011)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2637)
[M::mem_pestat] mean and std.dev: (619.17, 629.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3450)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 224, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 673)
[M::mem_pestat] mean and std.dev: (248.15, 123.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 847)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (239, 778, 1783)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4871)
[M::mem_pestat] mean and std.dev: (989.37, 1043.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6415)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (298, 486, 1376)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3532)
[M::mem_pestat] mean and std.dev: (859.26, 783.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4610)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705860 sequences (100000021 bp) in 2.163 CPU sec, 2.192 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (94, 280120, 40, 93)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 406, 983)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2557)
[M::mem_pestat] mean and std.dev: (484.39, 370.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3344)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 224, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 671)
[M::mem_pestat] mean and std.dev: (248.28, 122.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 844)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (372, 684, 1402)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3462)
[M::mem_pestat] mean and std.dev: (898.76, 769.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4492)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (236, 339, 947)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2369)
[M::mem_pestat] mean and std.dev: (557.71, 509.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3080)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 705226 reads in 233.846 CPU sec, 7.643 real sec
[M::mem_process_seqs] Processed 704764 reads in 161.665 CPU sec, 5.265 real sec
sorting block 5, #reads = 1070068 mem = 536878007 peak = 927264768
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (78, 280142, 39, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 550, 2255)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6371)
[M::mem_pestat] mean and std.dev: (1124.18, 1174.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8429)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 225, 323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 665)
[M::mem_pestat] mean and std.dev: (247.30, 121.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 836)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 592, 3564)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10368)
[M::mem_pestat] mean and std.dev: (1876.03, 2296.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13770)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (300, 601, 1167)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2901)
[M::mem_pestat] mean and std.dev: (788.00, 691.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3768)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704560 sequences (100000272 bp) in 2.658 CPU sec, 2.875 real sec...
[M::process] read 704382 sequences (100000022 bp) in 2.098 CPU sec, 2.129 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (80, 280408, 45, 79)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 380, 845)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2193)
[M::mem_pestat] mean and std.dev: (518.17, 527.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2867)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 221, 317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 651)
[M::mem_pestat] mean and std.dev: (243.06, 118.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 818)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (385, 753, 1879)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4867)
[M::mem_pestat] mean and std.dev: (1180.58, 1066.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6361)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (252, 459, 1026)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2574)
[M::mem_pestat] mean and std.dev: (576.71, 427.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3348)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704246 reads in 232.820 CPU sec, 7.520 real sec
sorting block 6, #reads = 1069415 mem = 536881103 peak = 927264768
[M::mem_process_seqs] Processed 705860 reads in 173.169 CPU sec, 5.686 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 280478, 54, 79)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 312, 583)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1339)
[M::mem_pestat] mean and std.dev: (366.84, 258.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1717)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 223, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 659)
[M::mem_pestat] mean and std.dev: (245.85, 119.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 828)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (481, 946, 1711)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4171)
[M::mem_pestat] mean and std.dev: (936.89, 695.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5401)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (251, 443, 1229)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3185)
[M::mem_pestat] mean and std.dev: (698.18, 621.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4163)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703618 sequences (100000097 bp) in 2.942 CPU sec, 3.143 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 280191, 35, 96)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 360, 625)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1563)
[M::mem_pestat] mean and std.dev: (403.29, 319.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2032)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 223, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 659)
[M::mem_pestat] mean and std.dev: (245.87, 119.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 828)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (261, 838, 2902)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8184)
[M::mem_pestat] mean and std.dev: (1513.82, 1693.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10825)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 362, 1122)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2954)
[M::mem_pestat] mean and std.dev: (697.65, 756.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3870)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703258 sequences (100000182 bp) in 2.348 CPU sec, 2.354 real sec...
[M::mem_process_seqs] Processed 704560 reads in 230.355 CPU sec, 7.479 real sec
sorting block 7, #reads = 1066577 mem = 536884892 peak = 927264768
[M::mem_process_seqs] Processed 704382 reads in 161.134 CPU sec, 5.160 real sec
sorting block 8, #reads = 1068704 mem = 536879173 peak = 927264768
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 280337, 58, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 380, 974)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2608)
[M::mem_pestat] mean and std.dev: (547.46, 565.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3425)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 224, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 657)
[M::mem_pestat] mean and std.dev: (246.20, 119.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 825)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (264, 892, 1284)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3324)
[M::mem_pestat] mean and std.dev: (768.47, 701.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4344)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (250, 460, 1191)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3073)
[M::mem_pestat] mean and std.dev: (762.48, 775.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4014)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703186 sequences (100000280 bp) in 2.693 CPU sec, 2.913 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 280738, 39, 76)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 237, 814)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2088)
[M::mem_pestat] mean and std.dev: (441.67, 393.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2725)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 225, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 666)
[M::mem_pestat] mean and std.dev: (248.02, 120.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 837)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (340, 714, 1299)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3217)
[M::mem_pestat] mean and std.dev: (868.97, 743.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4176)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (231, 448, 858)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2112)
[M::mem_pestat] mean and std.dev: (550.35, 403.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2739)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702722 sequences (100000189 bp) in 2.267 CPU sec, 2.330 real sec...
[M::mem_process_seqs] Processed 703618 reads in 228.431 CPU sec, 7.467 real sec
[M::mem_process_seqs] Processed 703258 reads in 161.430 CPU sec, 5.192 real sec
sorting block 9, #reads = 1070137 mem = 536881415 peak = 927264768
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 279996, 34, 73)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 314, 1303)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3543)
[M::mem_pestat] mean and std.dev: (668.48, 758.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4663)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 226, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 664)
[M::mem_pestat] mean and std.dev: (248.17, 120.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 834)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 537, 1203)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3305)
[M::mem_pestat] mean and std.dev: (703.32, 707.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4356)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 309, 875)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2253)
[M::mem_pestat] mean and std.dev: (477.69, 451.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2942)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 707338 sequences (100000215 bp) in 2.888 CPU sec, 3.155 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 279572, 52, 94)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 409, 863)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2175)
[M::mem_pestat] mean and std.dev: (477.16, 410.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2831)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 227, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 670)
[M::mem_pestat] mean and std.dev: (249.59, 121.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 842)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (276, 372, 1213)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3087)
[M::mem_pestat] mean and std.dev: (710.34, 697.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4024)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (383, 900, 1291)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3107)
[M::mem_pestat] mean and std.dev: (873.88, 719.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4015)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 707196 sequences (100000006 bp) in 2.375 CPU sec, 2.397 real sec...
[M::mem_process_seqs] Processed 703186 reads in 231.099 CPU sec, 7.550 real sec
[M::mem_process_seqs] Processed 702722 reads in 161.701 CPU sec, 5.188 real sec
sorting block 10, #reads = 1068406 mem = 536879257 peak = 927264768
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 281210, 48, 80)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (232, 620, 1440)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3856)
[M::mem_pestat] mean and std.dev: (846.78, 904.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5064)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 219, 317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 653)
[M::mem_pestat] mean and std.dev: (242.44, 119.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 821)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (227, 1067, 2737)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7757)
[M::mem_pestat] mean and std.dev: (1442.60, 1207.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10267)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (247, 355, 1045)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2641)
[M::mem_pestat] mean and std.dev: (623.64, 608.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3439)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706792 sequences (100000251 bp) in 2.777 CPU sec, 2.950 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 281647, 47, 82)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 382, 903)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2295)
[M::mem_pestat] mean and std.dev: (520.06, 422.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2991)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 219, 320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 664)
[M::mem_pestat] mean and std.dev: (243.79, 121.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 836)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (474, 894, 1088)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2316)
[M::mem_pestat] mean and std.dev: (872.13, 576.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3177)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 436, 1001)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2515)
[M::mem_pestat] mean and std.dev: (491.21, 433.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3272)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706472 sequences (100000146 bp) in 2.370 CPU sec, 2.373 real sec...
[M::mem_process_seqs] Processed 707338 reads in 224.409 CPU sec, 7.220 real sec
sorting block 11, #reads = 1068138 mem = 536881614 peak = 927264768
[M::mem_process_seqs] Processed 707196 reads in 159.816 CPU sec, 5.383 real sec
sorting block 12, #reads = 1070507 mem = 536878065 peak = 927264768
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 281678, 35, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 593, 1102)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2932)
[M::mem_pestat] mean and std.dev: (580.61, 416.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3847)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 220, 323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 671)
[M::mem_pestat] mean and std.dev: (245.99, 123.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 845)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (276, 567, 1818)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4902)
[M::mem_pestat] mean and std.dev: (513.63, 459.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6444)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 409, 1022)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2708)
[M::mem_pestat] mean and std.dev: (520.43, 471.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3551)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704960 sequences (100000240 bp) in 2.803 CPU sec, 2.999 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 281616, 51, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (281, 741, 1888)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5102)
[M::mem_pestat] mean and std.dev: (884.22, 941.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6709)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 222, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 678)
[M::mem_pestat] mean and std.dev: (247.72, 124.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 854)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (441, 819, 1789)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4485)
[M::mem_pestat] mean and std.dev: (1105.10, 834.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5833)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (235, 271, 541)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1153)
[M::mem_pestat] mean and std.dev: (312.45, 160.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1459)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704722 sequences (100000116 bp) in 2.341 CPU sec, 2.346 real sec...
[M::mem_process_seqs] Processed 706792 reads in 225.793 CPU sec, 7.479 real sec
[M::mem_process_seqs] Processed 706472 reads in 159.326 CPU sec, 5.104 real sec
sorting block 13, #reads = 1071759 mem = 536881703 peak = 927264768
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (89, 281006, 51, 73)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 336, 886)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2246)
[M::mem_pestat] mean and std.dev: (536.29, 452.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2926)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 225, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 686)
[M::mem_pestat] mean and std.dev: (250.87, 126.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 864)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (495, 1222, 1533)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3609)
[M::mem_pestat] mean and std.dev: (1023.93, 600.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4647)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (232, 319, 1268)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3340)
[M::mem_pestat] mean and std.dev: (525.44, 631.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4376)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705386 sequences (100000260 bp) in 2.912 CPU sec, 3.103 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (94, 280790, 39, 85)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 325, 776)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1962)
[M::mem_pestat] mean and std.dev: (432.14, 327.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2555)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 226, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 692)
[M::mem_pestat] mean and std.dev: (252.09, 127.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 872)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (251, 666, 1949)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5345)
[M::mem_pestat] mean and std.dev: (1008.28, 848.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7043)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (263, 431, 1532)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4070)
[M::mem_pestat] mean and std.dev: (810.53, 806.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5339)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705440 sequences (100000220 bp) in 2.251 CPU sec, 2.255 real sec...
[M::mem_process_seqs] Processed 704960 reads in 219.365 CPU sec, 7.033 real sec
[M::mem_process_seqs] Processed 704722 reads in 155.086 CPU sec, 4.957 real sec
sorting block 14, #reads = 1073369 mem = 536877780 peak = 927264768
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (86, 281190, 45, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 494, 1394)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3778)
[M::mem_pestat] mean and std.dev: (623.08, 533.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4970)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 224, 327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 679)
[M::mem_pestat] mean and std.dev: (249.37, 125.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 855)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 839, 1512)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4208)
[M::mem_pestat] mean and std.dev: (975.21, 923.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5556)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 423, 778)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1922)
[M::mem_pestat] mean and std.dev: (447.67, 311.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2494)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704828 sequences (100000122 bp) in 3.095 CPU sec, 3.282 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (106, 281086, 44, 91)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (257, 421, 1630)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4376)
[M::mem_pestat] mean and std.dev: (808.34, 801.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5749)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 223, 327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 679)
[M::mem_pestat] mean and std.dev: (248.50, 124.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 855)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 725, 966)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2556)
[M::mem_pestat] mean and std.dev: (726.32, 634.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3351)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 350, 968)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2514)
[M::mem_pestat] mean and std.dev: (539.51, 535.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3287)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704594 sequences (100000208 bp) in 2.322 CPU sec, 2.332 real sec...
[M::mem_process_seqs] Processed 705386 reads in 215.836 CPU sec, 6.901 real sec
sorting block 15, #reads = 1070877 mem = 536891439 peak = 927264768
[M::mem_process_seqs] Processed 705440 reads in 155.616 CPU sec, 5.219 real sec
sorting block 16, #reads = 1072358 mem = 536877780 peak = 927264768
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (74, 280531, 45, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 336, 591)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1335)
[M::mem_pestat] mean and std.dev: (324.57, 178.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1707)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 224, 327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 677)
[M::mem_pestat] mean and std.dev: (249.11, 124.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 852)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (403, 752, 1253)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2953)
[M::mem_pestat] mean and std.dev: (799.02, 644.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3803)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (230, 445, 859)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2117)
[M::mem_pestat] mean and std.dev: (459.73, 347.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2746)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704604 sequences (100000061 bp) in 3.029 CPU sec, 3.187 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (90, 280764, 37, 85)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 461, 1741)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4783)
[M::mem_pestat] mean and std.dev: (1109.17, 1342.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6479)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 224, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 668)
[M::mem_pestat] mean and std.dev: (247.96, 122.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 840)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (428, 902, 2257)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5915)
[M::mem_pestat] mean and std.dev: (1527.22, 1397.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7744)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (258, 500, 815)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1929)
[M::mem_pestat] mean and std.dev: (507.64, 370.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2486)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705330 sequences (100000286 bp) in 2.382 CPU sec, 2.388 real sec...
[M::mem_process_seqs] Processed 704828 reads in 219.744 CPU sec, 7.257 real sec
[M::mem_process_seqs] Processed 704594 reads in 155.470 CPU sec, 4.954 real sec
sorting block 17, #reads = 1069856 mem = 536878295 peak = 927264768
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (79, 280317, 42, 89)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 372, 1214)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3254)
[M::mem_pestat] mean and std.dev: (629.41, 654.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4274)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 223, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 662)
[M::mem_pestat] mean and std.dev: (246.45, 121.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 832)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (121, 568, 978)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2692)
[M::mem_pestat] mean and std.dev: (559.40, 546.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3549)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (249, 485, 910)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2232)
[M::mem_pestat] mean and std.dev: (577.93, 463.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2893)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706460 sequences (100000186 bp) in 2.926 CPU sec, 3.075 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (81, 280566, 37, 79)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (143, 465, 1541)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4337)
[M::mem_pestat] mean and std.dev: (760.87, 825.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5735)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 221, 320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 658)
[M::mem_pestat] mean and std.dev: (244.95, 120.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 827)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (280, 795, 2053)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5599)
[M::mem_pestat] mean and std.dev: (889.85, 926.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7372)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (277, 601, 1204)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3058)
[M::mem_pestat] mean and std.dev: (763.18, 644.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3985)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704790 sequences (100000174 bp) in 2.229 CPU sec, 2.241 real sec...
[M::mem_process_seqs] Processed 704604 reads in 217.640 CPU sec, 7.053 real sec
sorting block 18, #reads = 1069549 mem = 536879724 peak = 927264768
[M::mem_process_seqs] Processed 705330 reads in 153.332 CPU sec, 4.883 real sec
[M::process] read 704272 sequences (100000102 bp) in 2.594 CPU sec, 2.696 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 280664, 44, 75)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 517, 1211)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3307)
[M::mem_pestat] mean and std.dev: (763.45, 872.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4355)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 219, 316)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 650)
[M::mem_pestat] mean and std.dev: (242.26, 119.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 817)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 759, 1511)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4229)
[M::mem_pestat] mean and std.dev: (842.21, 819.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5588)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 435, 1044)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2728)
[M::mem_pestat] mean and std.dev: (633.03, 557.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3570)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703982 sequences (100000119 bp) in 2.020 CPU sec, 2.019 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 280161, 54, 76)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 379, 1251)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3421)
[M::mem_pestat] mean and std.dev: (718.17, 858.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4506)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 223, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 661)
[M::mem_pestat] mean and std.dev: (245.83, 120.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 831)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 1149, 2524)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7196)
[M::mem_pestat] mean and std.dev: (1540.73, 1703.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9532)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 356, 987)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2527)
[M::mem_pestat] mean and std.dev: (570.83, 491.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3297)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (79, 280728, 41, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (257, 418, 1170)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2996)
[M::mem_pestat] mean and std.dev: (757.25, 768.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3909)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 224, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 659)
[M::mem_pestat] mean and std.dev: (246.31, 120.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 828)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (251, 700, 1771)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4811)
[M::mem_pestat] mean and std.dev: (976.03, 924.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6331)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (273, 432, 596)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1242)
[M::mem_pestat] mean and std.dev: (426.20, 267.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1565)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 706460 reads in 298.631 CPU sec, 9.548 real sec
sorting block 19, #reads = 1067998 mem = 536881059 peak = 927264768
[M::mem_process_seqs] Processed 704790 reads in 234.706 CPU sec, 7.553 real sec
[M::mem_process_seqs] Processed 704272 reads in 267.201 CPU sec, 8.656 real sec
sorting block 20, #reads = 1066383 mem = 536881930 peak = 947216384
[M::process] read 703704 sequences (100000068 bp) in 3.195 CPU sec, 3.340 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 280456, 38, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 640, 2023)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5699)
[M::mem_pestat] mean and std.dev: (1179.35, 1413.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7537)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 225, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 660)
[M::mem_pestat] mean and std.dev: (246.91, 120.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 829)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 912, 1370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3666)
[M::mem_pestat] mean and std.dev: (820.32, 682.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4814)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 301, 448)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 944)
[M::mem_pestat] mean and std.dev: (308.26, 171.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1192)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703748 sequences (100000018 bp) in 2.886 CPU sec, 3.039 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 279991, 59, 81)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (249, 586, 1570)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4212)
[M::mem_pestat] mean and std.dev: (862.73, 758.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5533)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 225, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 666)
[M::mem_pestat] mean and std.dev: (247.86, 121.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 837)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (269, 767, 1533)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4061)
[M::mem_pestat] mean and std.dev: (861.32, 758.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5325)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 473, 687)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1605)
[M::mem_pestat] mean and std.dev: (434.29, 278.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2064)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703982 reads in 223.564 CPU sec, 7.201 real sec
sorting block 21, #reads = 1068823 mem = 536884080 peak = 947216384
[M::mem_process_seqs] Processed 703704 reads in 162.182 CPU sec, 5.154 real sec
[M::process] read 708658 sequences (100000193 bp) in 2.568 CPU sec, 2.646 real sec...
sorting block 22, #reads = 1068630 mem = 536878922 peak = 956817408
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 280453, 48, 76)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 470, 1001)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2617)
[M::mem_pestat] mean and std.dev: (628.66, 569.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3425)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 226, 327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 675)
[M::mem_pestat] mean and std.dev: (249.57, 122.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 849)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (281, 454, 1067)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2639)
[M::mem_pestat] mean and std.dev: (703.80, 740.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3665)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (248, 349, 936)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2312)
[M::mem_pestat] mean and std.dev: (549.78, 406.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3000)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 707448 sequences (100000027 bp) in 2.665 CPU sec, 2.809 real sec...
[M::process] read 706124 sequences (100000276 bp) in 2.120 CPU sec, 2.132 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (89, 281624, 38, 80)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 318, 948)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2402)
[M::mem_pestat] mean and std.dev: (515.57, 475.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3129)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 216, 315)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 651)
[M::mem_pestat] mean and std.dev: (240.90, 120.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 819)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 517, 745)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1903)
[M::mem_pestat] mean and std.dev: (523.22, 421.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2482)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 512, 1062)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2760)
[M::mem_pestat] mean and std.dev: (584.67, 441.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3609)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703748 reads in 224.926 CPU sec, 7.195 real sec
[M::mem_process_seqs] Processed 708658 reads in 162.797 CPU sec, 5.198 real sec
sorting block 23, #reads = 1068316 mem = 536880999 peak = 956817408
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (84, 281511, 58, 78)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (237, 448, 1517)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4077)
[M::mem_pestat] mean and std.dev: (1014.13, 1045.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5357)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 219, 320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 664)
[M::mem_pestat] mean and std.dev: (244.16, 122.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 836)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (133, 801, 2056)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5902)
[M::mem_pestat] mean and std.dev: (1129.82, 1148.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7825)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (261, 530, 765)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1773)
[M::mem_pestat] mean and std.dev: (508.26, 343.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2277)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705128 sequences (100000164 bp) in 2.825 CPU sec, 2.970 real sec...
[M::process] read 704548 sequences (100000095 bp) in 2.156 CPU sec, 2.165 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (81, 281134, 53, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (300, 421, 902)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2106)
[M::mem_pestat] mean and std.dev: (551.11, 437.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2708)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 222, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 672)
[M::mem_pestat] mean and std.dev: (247.12, 123.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 846)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (52, 244, 1004)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2908)
[M::mem_pestat] mean and std.dev: (393.96, 452.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3860)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 332, 1537)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4255)
[M::mem_pestat] mean and std.dev: (922.58, 1017.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5614)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 707448 reads in 219.669 CPU sec, 7.033 real sec
sorting block 24, #reads = 1071738 mem = 536880172 peak = 956817408
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 280922, 34, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (248, 352, 718)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1658)
[M::mem_pestat] mean and std.dev: (464.51, 346.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2128)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 224, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 682)
[M::mem_pestat] mean and std.dev: (249.66, 125.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 859)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (138, 687, 1905)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5439)
[M::mem_pestat] mean and std.dev: (1298.94, 1548.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7492)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 383, 1176)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3096)
[M::mem_pestat] mean and std.dev: (780.91, 789.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4056)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704170 sequences (100000074 bp) in 2.395 CPU sec, 2.406 real sec...
[M::mem_process_seqs] Processed 705128 reads in 126.464 CPU sec, 4.084 real sec
[M::mem_process_seqs] Processed 706124 reads in 325.777 CPU sec, 10.491 real sec
sorting block 25, #reads = 1070210 mem = 536888121 peak = 956817408
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (90, 281182, 42, 94)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (262, 403, 1480)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3916)
[M::mem_pestat] mean and std.dev: (749.70, 851.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5134)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 227, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 693)
[M::mem_pestat] mean and std.dev: (252.69, 126.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 873)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (402, 801, 1462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3582)
[M::mem_pestat] mean and std.dev: (918.41, 743.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4642)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (265, 373, 934)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2272)
[M::mem_pestat] mean and std.dev: (562.26, 486.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2941)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705234 sequences (100000162 bp) in 2.712 CPU sec, 2.961 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (97, 279846, 66, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (239, 535, 1567)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4223)
[M::mem_pestat] mean and std.dev: (914.81, 953.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5551)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 227, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 693)
[M::mem_pestat] mean and std.dev: (252.92, 127.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 873)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 588, 801)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2107)
[M::mem_pestat] mean and std.dev: (486.92, 347.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2760)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (252, 434, 670)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1506)
[M::mem_pestat] mean and std.dev: (404.22, 246.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1924)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704978 sequences (100000294 bp) in 2.180 CPU sec, 2.183 real sec...
[M::mem_process_seqs] Processed 704548 reads in 240.525 CPU sec, 7.657 real sec
sorting block 26, #reads = 1070349 mem = 536877200 peak = 956817408
[M::mem_process_seqs] Processed 704170 reads in 151.236 CPU sec, 4.796 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (79, 281158, 40, 89)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 343, 818)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2082)
[M::mem_pestat] mean and std.dev: (555.63, 487.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2714)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 223, 327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 679)
[M::mem_pestat] mean and std.dev: (249.50, 125.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 855)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (501, 764, 1535)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3603)
[M::mem_pestat] mean and std.dev: (887.11, 749.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4637)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 401, 740)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1830)
[M::mem_pestat] mean and std.dev: (421.89, 329.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2375)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704614 sequences (100000073 bp) in 2.848 CPU sec, 2.964 real sec...
[M::process] read 704298 sequences (100000253 bp) in 2.201 CPU sec, 2.207 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (101, 280946, 53, 82)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 488, 1061)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2821)
[M::mem_pestat] mean and std.dev: (645.27, 603.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3701)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 223, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 673)
[M::mem_pestat] mean and std.dev: (248.12, 123.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 847)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (324, 389, 1855)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4917)
[M::mem_pestat] mean and std.dev: (903.81, 986.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6448)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (250, 658, 1481)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3943)
[M::mem_pestat] mean and std.dev: (850.90, 718.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5174)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 705234 reads in 208.082 CPU sec, 6.593 real sec
sorting block 27, #reads = 1069667 mem = 536881401 peak = 956817408
[M::mem_process_seqs] Processed 704978 reads in 149.092 CPU sec, 4.744 real sec
sorting block 28, #reads = 1071224 mem = 536880786 peak = 956817408
[M::process] read 704398 sequences (100000018 bp) in 2.728 CPU sec, 2.802 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 280894, 50, 75)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (229, 561, 1440)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3862)
[M::mem_pestat] mean and std.dev: (772.20, 676.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5073)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 224, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 674)
[M::mem_pestat] mean and std.dev: (248.44, 123.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 848)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (255, 750, 1379)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3627)
[M::mem_pestat] mean and std.dev: (797.66, 817.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4751)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (248, 377, 569)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1211)
[M::mem_pestat] mean and std.dev: (381.60, 200.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1532)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705136 sequences (100000162 bp) in 2.278 CPU sec, 2.288 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (81, 280752, 51, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 317, 549)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1287)
[M::mem_pestat] mean and std.dev: (333.71, 238.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1656)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 223, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 668)
[M::mem_pestat] mean and std.dev: (247.37, 122.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 840)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (286, 565, 952)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2284)
[M::mem_pestat] mean and std.dev: (645.43, 496.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2950)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (256, 497, 1813)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4927)
[M::mem_pestat] mean and std.dev: (776.09, 862.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6484)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (91, 280761, 31, 86)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (270, 574, 1297)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3351)
[M::mem_pestat] mean and std.dev: (711.39, 595.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4378)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 223, 323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 665)
[M::mem_pestat] mean and std.dev: (247.09, 121.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 836)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (264, 451, 1161)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2955)
[M::mem_pestat] mean and std.dev: (445.64, 408.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3852)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (247, 368, 863)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2095)
[M::mem_pestat] mean and std.dev: (479.34, 368.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2711)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704614 reads in 298.600 CPU sec, 9.768 real sec
[M::mem_process_seqs] Processed 704298 reads in 236.237 CPU sec, 7.564 real sec
sorting block 29, #reads = 1069871 mem = 536877587 peak = 956817408
[M::mem_process_seqs] Processed 704398 reads in 267.845 CPU sec, 8.576 real sec
[M::process] read 704854 sequences (100000040 bp) in 2.791 CPU sec, 2.905 real sec...
sorting block 30, #reads = 1071305 mem = 536877315 peak = 956817408
[M::process] read 704488 sequences (100000181 bp) in 2.607 CPU sec, 2.676 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (101, 281018, 41, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 294, 926)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2430)
[M::mem_pestat] mean and std.dev: (486.13, 483.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3182)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 222, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 661)
[M::mem_pestat] mean and std.dev: (245.67, 120.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 831)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 466, 862)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2260)
[M::mem_pestat] mean and std.dev: (537.97, 478.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2959)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 396, 702)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1710)
[M::mem_pestat] mean and std.dev: (408.96, 279.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2214)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704854 reads in 124.085 CPU sec, 3.893 real sec
[M::process] read 704370 sequences (100000063 bp) in 2.142 CPU sec, 2.150 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 280845, 48, 87)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (265, 437, 971)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2383)
[M::mem_pestat] mean and std.dev: (612.52, 521.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3089)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 221, 320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 658)
[M::mem_pestat] mean and std.dev: (245.07, 120.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 827)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (288, 632, 1657)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4395)
[M::mem_pestat] mean and std.dev: (1013.11, 998.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5764)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (269, 472, 1390)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3632)
[M::mem_pestat] mean and std.dev: (798.26, 717.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4753)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (76, 280061, 52, 79)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 304, 821)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2105)
[M::mem_pestat] mean and std.dev: (465.99, 411.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2747)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 223, 323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 665)
[M::mem_pestat] mean and std.dev: (246.89, 121.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 836)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (396, 729, 1716)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4356)
[M::mem_pestat] mean and std.dev: (1015.06, 968.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5676)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 514, 1187)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3145)
[M::mem_pestat] mean and std.dev: (679.71, 577.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4124)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703770 sequences (100000167 bp) in 2.106 CPU sec, 2.115 real sec...
[M::mem_process_seqs] Processed 705136 reads in 331.723 CPU sec, 10.532 real sec
sorting block 31, #reads = 1068841 mem = 536878466 peak = 956817408
[M::mem_process_seqs] Processed 704488 reads in 188.088 CPU sec, 5.995 real sec
sorting block 32, #reads = 1068426 mem = 536877104 peak = 1030660096
[M::process] read 704030 sequences (100000069 bp) in 2.891 CPU sec, 2.997 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (82, 280559, 50, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (256, 478, 871)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2101)
[M::mem_pestat] mean and std.dev: (554.63, 457.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2716)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 223, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 668)
[M::mem_pestat] mean and std.dev: (247.20, 121.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 840)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (275, 642, 1470)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3860)
[M::mem_pestat] mean and std.dev: (853.07, 857.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5055)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 327, 855)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2145)
[M::mem_pestat] mean and std.dev: (556.21, 505.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2790)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703886 sequences (100000194 bp) in 2.200 CPU sec, 2.197 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (103, 280007, 51, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 428, 970)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2470)
[M::mem_pestat] mean and std.dev: (599.77, 539.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3220)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 225, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 666)
[M::mem_pestat] mean and std.dev: (247.97, 121.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 837)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (599, 1419, 3081)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8045)
[M::mem_pestat] mean and std.dev: (1773.55, 1509.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10527)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 239, 596)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1460)
[M::mem_pestat] mean and std.dev: (371.26, 336.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1892)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704370 reads in 208.767 CPU sec, 6.613 real sec
[M::mem_process_seqs] Processed 703770 reads in 239.386 CPU sec, 7.613 real sec
sorting block 33, #reads = 1068325 mem = 536879069 peak = 1030660096
[M::process] read 707322 sequences (100000225 bp) in 2.695 CPU sec, 2.800 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (93, 280544, 25, 72)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (291, 513, 1732)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4614)
[M::mem_pestat] mean and std.dev: (916.37, 830.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6055)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 224, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 666)
[M::mem_pestat] mean and std.dev: (247.69, 121.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 837)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 554, 1618)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4440)
[M::mem_pestat] mean and std.dev: (1017.56, 1159.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5851)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (261, 453, 1108)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2802)
[M::mem_pestat] mean and std.dev: (690.07, 578.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3649)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706802 sequences (100000044 bp) in 2.178 CPU sec, 2.177 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (98, 280301, 71, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (226, 588, 1228)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3232)
[M::mem_pestat] mean and std.dev: (787.29, 781.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4234)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 225, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 672)
[M::mem_pestat] mean and std.dev: (248.95, 122.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 845)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (363, 758, 2215)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5919)
[M::mem_pestat] mean and std.dev: (1202.97, 1246.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7771)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 505, 1147)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3011)
[M::mem_pestat] mean and std.dev: (576.69, 504.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3943)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704030 reads in 213.886 CPU sec, 6.790 real sec
sorting block 34, #reads = 1068668 mem = 536878714 peak = 1030660096
[M::mem_process_seqs] Processed 703886 reads in 152.586 CPU sec, 4.868 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (103, 281432, 51, 93)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 285, 790)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1932)
[M::mem_pestat] mean and std.dev: (460.65, 424.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2503)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::process] read 705748 sequences (100000092 bp) in 2.757 CPU sec, 2.857 real sec...
[M::mem_pestat] (25, 50, 75) percentile: (149, 221, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 665)
[M::mem_pestat] mean and std.dev: (245.26, 122.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 837)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (291, 631, 1156)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2886)
[M::mem_pestat] mean and std.dev: (672.73, 530.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3751)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (248, 521, 1103)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2813)
[M::mem_pestat] mean and std.dev: (696.95, 623.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3668)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704930 sequences (100000069 bp) in 1.840 CPU sec, 1.844 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 281530, 42, 81)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (146, 225, 481)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1151)
[M::mem_pestat] mean and std.dev: (295.21, 223.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1486)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 219, 318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 656)
[M::mem_pestat] mean and std.dev: (242.78, 120.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 825)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (399, 993, 1587)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3963)
[M::mem_pestat] mean and std.dev: (1002.76, 850.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5151)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 487, 1073)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2763)
[M::mem_pestat] mean and std.dev: (586.63, 455.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3608)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 706802 reads in 204.038 CPU sec, 6.474 real sec
sorting block 35, #reads = 1069305 mem = 536881945 peak = 1030660096
[M::mem_process_seqs] Processed 707322 reads in 236.927 CPU sec, 7.550 real sec
sorting block 36, #reads = 1071317 mem = 536882261 peak = 1030660096
[M::process] read 703808 sequences (100000233 bp) in 2.652 CPU sec, 2.751 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 281025, 55, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (251, 423, 831)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1991)
[M::mem_pestat] mean and std.dev: (513.55, 390.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2571)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 222, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 675)
[M::mem_pestat] mean and std.dev: (247.66, 124.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 850)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (232, 632, 1726)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4714)
[M::mem_pestat] mean and std.dev: (785.18, 765.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6208)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 406, 1075)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2817)
[M::mem_pestat] mean and std.dev: (609.65, 508.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3688)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702694 sequences (100000121 bp) in 2.220 CPU sec, 2.221 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 280496, 71, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 306, 662)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1596)
[M::mem_pestat] mean and std.dev: (380.90, 260.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2063)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 225, 327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 679)
[M::mem_pestat] mean and std.dev: (249.73, 125.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 855)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (252, 899, 2199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6093)
[M::mem_pestat] mean and std.dev: (1220.15, 1229.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8040)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (233, 387, 1274)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3356)
[M::mem_pestat] mean and std.dev: (674.12, 693.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4397)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 705748 reads in 201.189 CPU sec, 6.365 real sec
[M::process] read 704372 sequences (100000028 bp) in 2.535 CPU sec, 2.540 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (106, 279593, 61, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (269, 731, 1606)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4280)
[M::mem_pestat] mean and std.dev: (1082.68, 1086.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5617)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 230, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 704)
[M::mem_pestat] mean and std.dev: (255.96, 128.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 887)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (446, 988, 1316)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3056)
[M::mem_pestat] mean and std.dev: (871.40, 580.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3926)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 348, 1287)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3433)
[M::mem_pestat] mean and std.dev: (651.08, 659.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4506)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702694 reads in 112.908 CPU sec, 3.577 real sec
sorting block 37, #reads = 1072356 mem = 536879864 peak = 1030660096
[M::mem_process_seqs] Processed 704930 reads in 279.750 CPU sec, 8.901 real sec
sorting block 38, #reads = 1069998 mem = 536884330 peak = 1030660096
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (97, 280083, 33, 86)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 473, 1231)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3289)
[M::mem_pestat] mean and std.dev: (754.14, 804.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4318)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 227, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 690)
[M::mem_pestat] mean and std.dev: (252.80, 126.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 869)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (346, 642, 1164)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2800)
[M::mem_pestat] mean and std.dev: (646.41, 440.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3618)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (230, 447, 2316)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6488)
[M::mem_pestat] mean and std.dev: (1416.34, 1834.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8756)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704576 sequences (100000134 bp) in 2.844 CPU sec, 2.908 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 280828, 54, 81)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (299, 687, 1245)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3137)
[M::mem_pestat] mean and std.dev: (672.67, 530.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4083)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 226, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 686)
[M::mem_pestat] mean and std.dev: (251.21, 126.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 864)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (121, 482, 1255)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3523)
[M::mem_pestat] mean and std.dev: (573.09, 632.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4657)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (264, 538, 1118)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2826)
[M::mem_pestat] mean and std.dev: (764.77, 732.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3695)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704134 sequences (100000033 bp) in 2.210 CPU sec, 2.208 real sec...
[M::mem_process_seqs] Processed 703808 reads in 315.789 CPU sec, 9.999 real sec
[M::mem_process_seqs] Processed 704372 reads in 144.862 CPU sec, 4.587 real sec
sorting block 39, #reads = 1069415 mem = 536878115 peak = 1030660096
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (74, 280266, 45, 78)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 353, 1123)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2953)
[M::mem_pestat] mean and std.dev: (542.94, 591.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3868)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 224, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 671)
[M::mem_pestat] mean and std.dev: (248.30, 123.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 844)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (230, 544, 933)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2339)
[M::mem_pestat] mean and std.dev: (595.69, 468.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3042)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (251, 540, 1017)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2549)
[M::mem_pestat] mean and std.dev: (637.94, 543.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3315)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704126 sequences (100000117 bp) in 2.812 CPU sec, 2.944 real sec...
[M::process] read 704588 sequences (100000198 bp) in 2.190 CPU sec, 2.184 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (88, 279922, 35, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 274, 675)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1629)
[M::mem_pestat] mean and std.dev: (384.57, 312.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2106)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 224, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 671)
[M::mem_pestat] mean and std.dev: (248.51, 123.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 844)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (282, 1138, 3886)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 11094)
[M::mem_pestat] mean and std.dev: (2463.06, 2874.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14698)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 384, 793)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2011)
[M::mem_pestat] mean and std.dev: (486.77, 418.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2620)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704576 reads in 197.721 CPU sec, 6.295 real sec
sorting block 40, #reads = 1070893 mem = 536884933 peak = 1030660096
[M::mem_process_seqs] Processed 704134 reads in 142.604 CPU sec, 4.547 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 280165, 53, 91)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (237, 435, 1171)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3039)
[M::mem_pestat] mean and std.dev: (650.52, 582.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3973)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 224, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 668)
[M::mem_pestat] mean and std.dev: (247.90, 122.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 840)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 905, 2079)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5941)
[M::mem_pestat] mean and std.dev: (1128.53, 1102.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7872)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (249, 323, 604)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1314)
[M::mem_pestat] mean and std.dev: (376.74, 250.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1669)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704050 sequences (100000237 bp) in 2.726 CPU sec, 2.803 real sec...
[M::process] read 704248 sequences (100000301 bp) in 2.200 CPU sec, 2.196 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (94, 280770, 58, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 419, 1310)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3514)
[M::mem_pestat] mean and std.dev: (631.36, 661.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4616)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 223, 323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 665)
[M::mem_pestat] mean and std.dev: (246.93, 121.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 836)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 602, 1079)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2775)
[M::mem_pestat] mean and std.dev: (679.45, 627.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3623)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 370, 1079)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2877)
[M::mem_pestat] mean and std.dev: (648.35, 620.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3776)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704126 reads in 195.181 CPU sec, 6.174 real sec
sorting block 41, #reads = 1069377 mem = 536879490 peak = 1030660096
[M::mem_process_seqs] Processed 704588 reads in 148.067 CPU sec, 4.716 real sec
sorting block 42, #reads = 1069774 mem = 536878719 peak = 1030660096
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (91, 280450, 49, 72)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (232, 419, 1247)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3277)
[M::mem_pestat] mean and std.dev: (711.41, 655.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4292)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 224, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 671)
[M::mem_pestat] mean and std.dev: (248.14, 122.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 844)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 893, 1836)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5126)
[M::mem_pestat] mean and std.dev: (1032.40, 907.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6771)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (245, 598, 954)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2372)
[M::mem_pestat] mean and std.dev: (603.33, 399.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3081)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704490 sequences (100000268 bp) in 2.964 CPU sec, 3.125 real sec...
[M::process] read 704106 sequences (100000184 bp) in 2.006 CPU sec, 2.012 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 280436, 74, 76)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 402, 934)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2392)
[M::mem_pestat] mean and std.dev: (533.99, 494.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3121)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 223, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 668)
[M::mem_pestat] mean and std.dev: (247.50, 122.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 840)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (321, 887, 1560)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4038)
[M::mem_pestat] mean and std.dev: (917.83, 818.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5277)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (338, 618, 1969)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5231)
[M::mem_pestat] mean and std.dev: (1089.31, 1197.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6862)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704050 reads in 198.679 CPU sec, 6.307 real sec
[M::mem_process_seqs] Processed 704248 reads in 145.886 CPU sec, 4.646 real sec
sorting block 43, #reads = 1069175 mem = 536879011 peak = 1030660096
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (83, 280881, 41, 74)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 316, 1111)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2907)
[M::mem_pestat] mean and std.dev: (669.13, 737.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3805)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 222, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 664)
[M::mem_pestat] mean and std.dev: (246.54, 122.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 835)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 307, 965)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2559)
[M::mem_pestat] mean and std.dev: (598.75, 538.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3356)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 428, 906)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2268)
[M::mem_pestat] mean and std.dev: (443.90, 388.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2949)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703540 sequences (100000271 bp) in 2.869 CPU sec, 2.947 real sec...
[M::process] read 702958 sequences (100000005 bp) in 2.170 CPU sec, 2.162 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 279882, 62, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 400, 1028)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2682)
[M::mem_pestat] mean and std.dev: (577.21, 511.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3509)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 223, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 662)
[M::mem_pestat] mean and std.dev: (246.74, 121.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 832)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (272, 539, 1074)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2678)
[M::mem_pestat] mean and std.dev: (771.07, 709.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3611)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (234, 361, 1131)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2925)
[M::mem_pestat] mean and std.dev: (575.30, 557.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3822)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704490 reads in 189.875 CPU sec, 5.996 real sec
sorting block 44, #reads = 1068015 mem = 536879394 peak = 1030660096
[M::mem_process_seqs] Processed 704106 reads in 220.235 CPU sec, 6.983 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 280406, 38, 102)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 392, 1016)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2650)
[M::mem_pestat] mean and std.dev: (633.37, 601.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3467)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 225, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 672)
[M::mem_pestat] mean and std.dev: (249.07, 122.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 845)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (288, 751, 1189)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2991)
[M::mem_pestat] mean and std.dev: (741.64, 647.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3892)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 493, 799)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1995)
[M::mem_pestat] mean and std.dev: (515.60, 393.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2593)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703070 sequences (100000113 bp) in 2.545 CPU sec, 2.593 real sec...
[M::process] read 712706 sequences (100000172 bp) in 2.190 CPU sec, 2.189 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 279994, 41, 85)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (235, 488, 1111)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2863)
[M::mem_pestat] mean and std.dev: (677.10, 548.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3739)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 227, 327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 673)
[M::mem_pestat] mean and std.dev: (250.04, 122.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 846)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (415, 859, 1561)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3853)
[M::mem_pestat] mean and std.dev: (940.39, 688.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4999)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 510, 1260)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3378)
[M::mem_pestat] mean and std.dev: (688.81, 635.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4437)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703540 reads in 196.542 CPU sec, 6.226 real sec
sorting block 45, #reads = 1068774 mem = 536878929 peak = 1030660096
[M::mem_process_seqs] Processed 702958 reads in 150.992 CPU sec, 4.805 real sec
sorting block 46, #reads = 1068720 mem = 536881195 peak = 1030660096
[M::process] read 711834 sequences (100000083 bp) in 2.759 CPU sec, 2.841 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (84, 283582, 33, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (260, 341, 824)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1952)
[M::mem_pestat] mean and std.dev: (487.79, 371.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2516)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (142, 206, 300)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 616)
[M::mem_pestat] mean and std.dev: (230.62, 115.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 774)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 1052, 1795)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4987)
[M::mem_pestat] mean and std.dev: (1229.03, 1213.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6583)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 302, 703)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1653)
[M::mem_pestat] mean and std.dev: (412.55, 338.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2128)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 710838 sequences (100000150 bp) in 2.270 CPU sec, 2.274 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (86, 279993, 35, 74)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (225, 536, 1426)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3828)
[M::mem_pestat] mean and std.dev: (803.34, 753.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5029)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 228, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 679)
[M::mem_pestat] mean and std.dev: (251.54, 124.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 854)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (352, 657, 2215)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5941)
[M::mem_pestat] mean and std.dev: (1229.76, 1338.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7804)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (248, 468, 1210)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3134)
[M::mem_pestat] mean and std.dev: (732.31, 619.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4096)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 712706 reads in 202.157 CPU sec, 6.398 real sec
[M::mem_process_seqs] Processed 703070 reads in 231.145 CPU sec, 7.338 real sec
sorting block 47, #reads = 1070499 mem = 536877730 peak = 1030660096
[M::process] read 708858 sequences (100000227 bp) in 2.785 CPU sec, 2.866 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 283774, 38, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 278, 1371)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3721)
[M::mem_pestat] mean and std.dev: (693.73, 776.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4896)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (143, 208, 304)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 626)
[M::mem_pestat] mean and std.dev: (233.34, 117.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 787)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 528, 1530)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4168)
[M::mem_pestat] mean and std.dev: (755.97, 826.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5487)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (294, 749, 1182)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2958)
[M::mem_pestat] mean and std.dev: (722.67, 530.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3846)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 707826 sequences (100000032 bp) in 1.710 CPU sec, 1.711 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 283535, 34, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 459, 1430)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3860)
[M::mem_pestat] mean and std.dev: (688.65, 676.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5075)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (144, 210, 306)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 630)
[M::mem_pestat] mean and std.dev: (235.12, 117.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 792)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (238, 545, 1108)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2848)
[M::mem_pestat] mean and std.dev: (633.84, 574.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3718)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (262, 418, 947)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2317)
[M::mem_pestat] mean and std.dev: (673.18, 599.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3071)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 711834 reads in 204.841 CPU sec, 6.501 real sec
sorting block 48, #reads = 1069633 mem = 536878927 peak = 1030660096
[M::mem_process_seqs] Processed 710838 reads in 233.330 CPU sec, 7.426 real sec
[M::process] read 709106 sequences (100000140 bp) in 2.359 CPU sec, 2.424 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 282536, 60, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 397, 1130)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2942)
[M::mem_pestat] mean and std.dev: (562.60, 519.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3848)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 214, 315)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 651)
[M::mem_pestat] mean and std.dev: (240.73, 121.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 819)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (406, 893, 1479)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3625)
[M::mem_pestat] mean and std.dev: (976.25, 770.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4698)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 299, 813)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2109)
[M::mem_pestat] mean and std.dev: (469.33, 431.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2757)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 710960 sequences (100000056 bp) in 2.300 CPU sec, 2.303 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (89, 282419, 37, 86)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (236, 522, 1460)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3908)
[M::mem_pestat] mean and std.dev: (767.42, 745.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5132)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 216, 319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 661)
[M::mem_pestat] mean and std.dev: (243.39, 122.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 832)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (705, 1031, 1601)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3393)
[M::mem_pestat] mean and std.dev: (927.59, 555.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4289)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (318, 698, 1034)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2466)
[M::mem_pestat] mean and std.dev: (723.33, 525.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3182)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 282961, 42, 80)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 377, 1176)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3160)
[M::mem_pestat] mean and std.dev: (587.39, 524.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4152)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 214, 313)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 647)
[M::mem_pestat] mean and std.dev: (239.45, 120.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 814)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (261, 924, 1464)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3870)
[M::mem_pestat] mean and std.dev: (831.47, 681.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5073)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 440, 1086)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2874)
[M::mem_pestat] mean and std.dev: (551.19, 609.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3768)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 708858 reads in 280.295 CPU sec, 8.924 real sec
sorting block 49, #reads = 1070971 mem = 536881129 peak = 1030660096
[M::mem_process_seqs] Processed 707826 reads in 221.152 CPU sec, 7.074 real sec
[M::mem_process_seqs] Processed 709106 reads in 252.385 CPU sec, 8.080 real sec
sorting block 50, #reads = 1069284 mem = 536879956 peak = 1043775488
[M::process] read 710410 sequences (100000192 bp) in 2.948 CPU sec, 3.043 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 282984, 30, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 326, 793)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1939)
[M::mem_pestat] mean and std.dev: (487.90, 486.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2512)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (144, 209, 305)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 627)
[M::mem_pestat] mean and std.dev: (233.99, 116.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 788)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (228, 783, 991)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2517)
[M::mem_pestat] mean and std.dev: (645.59, 490.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3280)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 303, 783)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1941)
[M::mem_pestat] mean and std.dev: (388.98, 270.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2520)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 709704 sequences (100000122 bp) in 2.593 CPU sec, 2.621 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 282627, 46, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (237, 657, 2097)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5817)
[M::mem_pestat] mean and std.dev: (1126.65, 1048.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7677)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 210, 305)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 625)
[M::mem_pestat] mean and std.dev: (234.46, 116.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 785)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 1423, 4817)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 14007)
[M::mem_pestat] mean and std.dev: (2558.28, 2675.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 18602)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 306, 979)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2539)
[M::mem_pestat] mean and std.dev: (491.84, 503.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3319)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 708222 sequences (100000115 bp) in 2.190 CPU sec, 2.193 real sec...
[M::mem_process_seqs] Processed 710960 reads in 219.201 CPU sec, 6.930 real sec
sorting block 51, #reads = 1069908 mem = 536878239 peak = 1043775488
[M::mem_process_seqs] Processed 710410 reads in 157.421 CPU sec, 4.964 real sec
sorting block 52, #reads = 1067767 mem = 536885089 peak = 1043775488
[M::process] read 711354 sequences (100000063 bp) in 2.577 CPU sec, 2.677 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (79, 282441, 66, 72)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 442, 1142)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3016)
[M::mem_pestat] mean and std.dev: (608.15, 533.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3953)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 211, 309)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 637)
[M::mem_pestat] mean and std.dev: (236.84, 118.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 801)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 613, 981)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2637)
[M::mem_pestat] mean and std.dev: (627.33, 610.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3465)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 412, 883)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2223)
[M::mem_pestat] mean and std.dev: (456.48, 324.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2893)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 708700 sequences (100000216 bp) in 2.340 CPU sec, 2.345 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 281754, 69, 101)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 351, 864)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2244)
[M::mem_pestat] mean and std.dev: (457.92, 415.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2934)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 215, 314)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 648)
[M::mem_pestat] mean and std.dev: (239.76, 119.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 815)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (277, 527, 817)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1897)
[M::mem_pestat] mean and std.dev: (541.63, 402.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2437)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (261, 404, 1268)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3282)
[M::mem_pestat] mean and std.dev: (669.22, 634.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4289)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 709704 reads in 218.378 CPU sec, 6.924 real sec
[M::mem_process_seqs] Processed 708222 reads in 252.249 CPU sec, 8.030 real sec
sorting block 53, #reads = 1065781 mem = 536882960 peak = 1043775488
[M::process] read 707406 sequences (100000175 bp) in 2.265 CPU sec, 2.336 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (74, 282076, 53, 82)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (234, 534, 1135)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2937)
[M::mem_pestat] mean and std.dev: (732.81, 746.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3838)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (144, 208, 303)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 621)
[M::mem_pestat] mean and std.dev: (232.66, 115.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 780)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (244, 951, 1496)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4000)
[M::mem_pestat] mean and std.dev: (850.90, 596.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5252)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 462, 988)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2582)
[M::mem_pestat] mean and std.dev: (515.89, 438.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3379)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 707096 sequences (100000073 bp) in 1.800 CPU sec, 1.792 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (108, 281564, 57, 75)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 329, 1065)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2829)
[M::mem_pestat] mean and std.dev: (588.50, 612.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3711)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 213, 309)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 635)
[M::mem_pestat] mean and std.dev: (237.47, 117.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 798)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (444, 851, 2354)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6174)
[M::mem_pestat] mean and std.dev: (1271.06, 1204.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8084)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (250, 390, 1154)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2962)
[M::mem_pestat] mean and std.dev: (569.66, 519.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3866)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 711354 reads in 251.649 CPU sec, 8.014 real sec
sorting block 54, #reads = 1062508 mem = 536883739 peak = 1043775488
[M::mem_process_seqs] Processed 708700 reads in 288.310 CPU sec, 9.202 real sec
[M::process] read 707808 sequences (100000007 bp) in 2.559 CPU sec, 2.660 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (80, 280861, 41, 72)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (252, 438, 1234)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3198)
[M::mem_pestat] mean and std.dev: (646.11, 588.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4180)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 216, 313)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 643)
[M::mem_pestat] mean and std.dev: (240.19, 118.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 808)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (265, 784, 1648)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4414)
[M::mem_pestat] mean and std.dev: (896.03, 821.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5797)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 463, 843)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2089)
[M::mem_pestat] mean and std.dev: (482.22, 394.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2712)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 712724 sequences (100000258 bp) in 1.880 CPU sec, 1.878 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 281027, 45, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 403, 1313)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3523)
[M::mem_pestat] mean and std.dev: (697.76, 773.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4628)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 216, 315)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 649)
[M::mem_pestat] mean and std.dev: (241.88, 120.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 816)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (260, 797, 1374)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3602)
[M::mem_pestat] mean and std.dev: (803.38, 669.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4716)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (271, 511, 1454)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3820)
[M::mem_pestat] mean and std.dev: (722.64, 656.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5003)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 707406 reads in 228.944 CPU sec, 7.280 real sec
sorting block 55, #reads = 1060492 mem = 536877852 peak = 1043775488
[M::mem_process_seqs] Processed 707096 reads in 265.178 CPU sec, 8.456 real sec
sorting block 56, #reads = 1062809 mem = 536885115 peak = 1068122112
[M::process] read 715278 sequences (100000077 bp) in 2.260 CPU sec, 2.331 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 282788, 54, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 372, 981)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2629)
[M::mem_pestat] mean and std.dev: (551.40, 580.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3453)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (142, 205, 298)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 610)
[M::mem_pestat] mean and std.dev: (229.70, 114.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 766)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (110, 596, 1657)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4751)
[M::mem_pestat] mean and std.dev: (810.96, 848.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6298)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 409, 1112)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2898)
[M::mem_pestat] mean and std.dev: (628.57, 643.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3791)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 712622 sequences (100000152 bp) in 1.790 CPU sec, 1.792 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 281691, 55, 72)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (267, 441, 952)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2322)
[M::mem_pestat] mean and std.dev: (533.21, 384.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3007)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 215, 311)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 639)
[M::mem_pestat] mean and std.dev: (239.01, 118.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 803)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (288, 712, 1723)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4593)
[M::mem_pestat] mean and std.dev: (756.88, 730.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6028)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 399, 1136)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2966)
[M::mem_pestat] mean and std.dev: (552.66, 469.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3881)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 712724 reads in 239.018 CPU sec, 7.604 real sec
[M::mem_process_seqs] Processed 707808 reads in 273.151 CPU sec, 8.717 real sec
sorting block 57, #reads = 1061160 mem = 536884775 peak = 1068122112
[M::process] read 710186 sequences (100000070 bp) in 3.049 CPU sec, 3.120 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 284263, 37, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 370, 1033)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2757)
[M::mem_pestat] mean and std.dev: (567.92, 542.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3619)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (140, 201, 291)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 593)
[M::mem_pestat] mean and std.dev: (224.76, 110.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 744)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 1159, 2103)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5955)
[M::mem_pestat] mean and std.dev: (992.34, 933.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7881)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 334, 840)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2162)
[M::mem_pestat] mean and std.dev: (409.79, 341.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2823)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 708870 sequences (100000095 bp) in 2.300 CPU sec, 2.300 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 283920, 24, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (228, 413, 1450)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3894)
[M::mem_pestat] mean and std.dev: (746.50, 802.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5116)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (142, 206, 300)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 616)
[M::mem_pestat] mean and std.dev: (230.98, 114.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 774)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (707, 1386, 3943)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10415)
[M::mem_pestat] mean and std.dev: (2011.42, 1885.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13651)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 331, 650)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1528)
[M::mem_pestat] mean and std.dev: (368.78, 265.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1967)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 715278 reads in 239.142 CPU sec, 7.579 real sec
sorting block 58, #reads = 1060448 mem = 536880810 peak = 1068122112
[M::mem_process_seqs] Processed 712622 reads in 272.647 CPU sec, 8.674 real sec
sorting block 59, #reads = 1064530 mem = 536881609 peak = 1068122112
[M::process] read 709306 sequences (100000223 bp) in 2.797 CPU sec, 2.840 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (81, 283152, 51, 103)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 474, 954)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2414)
[M::mem_pestat] mean and std.dev: (640.09, 600.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3144)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 211, 308)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 634)
[M::mem_pestat] mean and std.dev: (236.40, 117.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 797)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (372, 558, 1093)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2535)
[M::mem_pestat] mean and std.dev: (609.00, 489.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3256)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (258, 372, 1072)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2700)
[M::mem_pestat] mean and std.dev: (591.39, 462.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3514)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 709306 sequences (100000258 bp) in 1.894 CPU sec, 1.919 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 282923, 51, 86)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 713, 1414)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3854)
[M::mem_pestat] mean and std.dev: (878.92, 852.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5074)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 214, 314)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 648)
[M::mem_pestat] mean and std.dev: (240.02, 119.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 815)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (429, 698, 1152)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2598)
[M::mem_pestat] mean and std.dev: (717.80, 431.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3321)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (269, 434, 834)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1964)
[M::mem_pestat] mean and std.dev: (549.56, 388.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2529)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 282881, 48, 96)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 297, 722)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1814)
[M::mem_pestat] mean and std.dev: (439.97, 360.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2360)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 212, 309)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 635)
[M::mem_pestat] mean and std.dev: (237.40, 118.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 798)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (333, 639, 1165)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2829)
[M::mem_pestat] mean and std.dev: (677.75, 615.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3661)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 380, 635)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1513)
[M::mem_pestat] mean and std.dev: (439.20, 332.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1952)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 710186 reads in 309.513 CPU sec, 9.888 real sec
[M::mem_process_seqs] Processed 708870 reads in 246.119 CPU sec, 7.905 real sec
[M::mem_process_seqs] Processed 709306 reads in 276.558 CPU sec, 8.878 real sec
sorting block 60, #reads = 1064159 mem = 536878846 peak = 1068122112
[M::process] read 708954 sequences (100000248 bp) in 2.880 CPU sec, 2.995 real sec...
sorting block 61, #reads = 1068107 mem = 536878118 peak = 1068122112
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (83, 282954, 45, 96)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (275, 559, 1097)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2741)
[M::mem_pestat] mean and std.dev: (769.60, 661.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3563)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 212, 308)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 632)
[M::mem_pestat] mean and std.dev: (236.82, 117.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 794)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (337, 770, 1455)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3691)
[M::mem_pestat] mean and std.dev: (819.45, 566.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4809)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 399, 1480)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3994)
[M::mem_pestat] mean and std.dev: (714.67, 763.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5251)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 709428 sequences (100000090 bp) in 2.591 CPU sec, 2.638 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 282043, 32, 74)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 427, 1344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3614)
[M::mem_pestat] mean and std.dev: (796.59, 839.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4749)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 212, 310)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 638)
[M::mem_pestat] mean and std.dev: (237.52, 118.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 802)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 469, 2187)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6247)
[M::mem_pestat] mean and std.dev: (1230.88, 1391.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8277)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (246, 642, 1757)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4779)
[M::mem_pestat] mean and std.dev: (1155.13, 1266.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6290)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 709306 reads in 212.609 CPU sec, 6.715 real sec
[M::process] read 710880 sequences (100000118 bp) in 2.330 CPU sec, 2.334 real sec...
[M::mem_process_seqs] Processed 708954 reads in 152.075 CPU sec, 4.784 real sec
sorting block 62, #reads = 1069342 mem = 536889121 peak = 1068122112
[M::process] read 706248 sequences (100000187 bp) in 3.060 CPU sec, 3.158 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 282781, 41, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (241, 509, 1204)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3130)
[M::mem_pestat] mean and std.dev: (712.18, 618.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4093)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 211, 308)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 634)
[M::mem_pestat] mean and std.dev: (236.35, 117.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 797)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (145, 654, 1454)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4072)
[M::mem_pestat] mean and std.dev: (864.08, 842.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5381)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (253, 459, 1139)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2911)
[M::mem_pestat] mean and std.dev: (528.67, 443.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3797)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706016 sequences (100000212 bp) in 2.300 CPU sec, 2.300 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 282045, 44, 77)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 284, 970)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2544)
[M::mem_pestat] mean and std.dev: (533.05, 580.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3331)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (144, 208, 303)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 621)
[M::mem_pestat] mean and std.dev: (233.16, 115.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 780)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (412, 618, 1421)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3439)
[M::mem_pestat] mean and std.dev: (685.52, 528.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4448)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 318, 790)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2026)
[M::mem_pestat] mean and std.dev: (415.74, 399.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2644)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 709428 reads in 235.242 CPU sec, 7.455 real sec
sorting block 63, #reads = 1064868 mem = 536880398 peak = 1068122112
[M::mem_process_seqs] Processed 710880 reads in 274.092 CPU sec, 8.724 real sec
[M::process] read 705488 sequences (100000235 bp) in 2.704 CPU sec, 2.761 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (73, 280717, 42, 83)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (259, 438, 1306)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3400)
[M::mem_pestat] mean and std.dev: (750.08, 715.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4447)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 218, 317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 653)
[M::mem_pestat] mean and std.dev: (243.24, 121.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 821)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (309, 636, 2648)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7326)
[M::mem_pestat] mean and std.dev: (1436.41, 1853.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9665)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 317, 945)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2443)
[M::mem_pestat] mean and std.dev: (558.85, 545.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3192)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705660 sequences (100000191 bp) in 2.270 CPU sec, 2.273 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 280699, 65, 82)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (244, 542, 1470)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3922)
[M::mem_pestat] mean and std.dev: (687.89, 691.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5148)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 217, 317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 653)
[M::mem_pestat] mean and std.dev: (242.98, 121.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 821)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (344, 945, 1461)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3695)
[M::mem_pestat] mean and std.dev: (819.53, 733.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4812)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (242, 528, 1295)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3401)
[M::mem_pestat] mean and std.dev: (715.96, 720.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4454)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 706016 reads in 211.647 CPU sec, 6.696 real sec
sorting block 64, #reads = 1059455 mem = 536882845 peak = 1068122112
[M::process] read 705570 sequences (100000239 bp) in 2.527 CPU sec, 2.537 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 280772, 46, 82)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 352, 726)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1744)
[M::mem_pestat] mean and std.dev: (448.43, 357.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2253)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 219, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 663)
[M::mem_pestat] mean and std.dev: (245.44, 123.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 834)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 642, 1761)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4903)
[M::mem_pestat] mean and std.dev: (937.35, 991.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6474)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 345, 869)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2173)
[M::mem_pestat] mean and std.dev: (530.11, 418.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2825)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 705660 reads in 119.867 CPU sec, 3.796 real sec
sorting block 65, #reads = 1067251 mem = 536879896 peak = 1068122112
[M::mem_process_seqs] Processed 706248 reads in 386.798 CPU sec, 12.284 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (74, 280529, 48, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 324, 524)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1220)
[M::mem_pestat] mean and std.dev: (308.71, 191.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1568)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 219, 320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 660)
[M::mem_pestat] mean and std.dev: (245.36, 123.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 830)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (515, 1002, 1416)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3218)
[M::mem_pestat] mean and std.dev: (955.51, 686.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4119)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 349, 530)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1242)
[M::mem_pestat] mean and std.dev: (318.72, 192.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1598)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 712322 sequences (100000025 bp) in 2.891 CPU sec, 2.983 real sec...
[M::process] read 709660 sequences (100000288 bp) in 1.970 CPU sec, 1.970 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 280525, 35, 83)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 296, 837)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2153)
[M::mem_pestat] mean and std.dev: (450.86, 466.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2811)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 219, 318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 654)
[M::mem_pestat] mean and std.dev: (244.03, 121.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 822)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (493, 920, 2087)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5275)
[M::mem_pestat] mean and std.dev: (1150.28, 1005.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6869)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 286, 787)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1983)
[M::mem_pestat] mean and std.dev: (416.86, 342.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2581)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 705488 reads in 335.543 CPU sec, 10.638 real sec
sorting block 66, #reads = 1066858 mem = 536878405 peak = 1068122112
[M::process] read 708658 sequences (100000064 bp) in 1.837 CPU sec, 1.842 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (93, 282798, 59, 82)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (247, 352, 1243)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3235)
[M::mem_pestat] mean and std.dev: (608.85, 543.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4231)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 213, 312)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 644)
[M::mem_pestat] mean and std.dev: (238.95, 120.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 810)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 620, 1594)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4352)
[M::mem_pestat] mean and std.dev: (863.87, 951.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5731)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 357, 1264)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3396)
[M::mem_pestat] mean and std.dev: (713.10, 782.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4462)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 709660 reads in 115.743 CPU sec, 3.683 real sec
sorting block 67, #reads = 1069941 mem = 536880307 peak = 1068122112
[M::mem_process_seqs] Processed 705570 reads in 303.365 CPU sec, 9.658 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 283344, 46, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 386, 970)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2526)
[M::mem_pestat] mean and std.dev: (564.72, 545.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3304)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (142, 206, 300)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 616)
[M::mem_pestat] mean and std.dev: (230.82, 115.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 774)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 366, 1759)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4879)
[M::mem_pestat] mean and std.dev: (892.74, 1210.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6439)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 409, 950)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2456)
[M::mem_pestat] mean and std.dev: (573.37, 523.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3209)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705712 sequences (100000058 bp) in 2.630 CPU sec, 2.737 real sec...
[M::process] read 705934 sequences (100000226 bp) in 2.200 CPU sec, 2.196 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (76, 282778, 40, 73)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 333, 666)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1580)
[M::mem_pestat] mean and std.dev: (361.34, 259.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2037)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 215, 315)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 651)
[M::mem_pestat] mean and std.dev: (240.56, 121.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 819)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (229, 636, 1273)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3361)
[M::mem_pestat] mean and std.dev: (654.65, 690.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4405)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 348, 704)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1742)
[M::mem_pestat] mean and std.dev: (397.37, 281.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2261)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 712322 reads in 329.119 CPU sec, 10.438 real sec
sorting block 68, #reads = 1059989 mem = 536879400 peak = 1068122112
[M::mem_process_seqs] Processed 708658 reads in 149.447 CPU sec, 4.750 real sec
sorting block 69, #reads = 1072016 mem = 536878356 peak = 1068122112
[M::process] read 707764 sequences (100000288 bp) in 2.451 CPU sec, 2.587 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (81, 281577, 47, 81)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 275, 640)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1596)
[M::mem_pestat] mean and std.dev: (331.36, 250.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2074)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 221, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 678)
[M::mem_pestat] mean and std.dev: (248.15, 124.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 854)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (244, 645, 1125)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2887)
[M::mem_pestat] mean and std.dev: (614.68, 506.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3768)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 303, 831)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2141)
[M::mem_pestat] mean and std.dev: (415.89, 366.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2796)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 708216 sequences (100000286 bp) in 1.817 CPU sec, 1.817 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (87, 282001, 44, 72)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 309, 1444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3968)
[M::mem_pestat] mean and std.dev: (796.72, 964.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5230)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 221, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 678)
[M::mem_pestat] mean and std.dev: (248.49, 126.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 854)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 307, 2655)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7531)
[M::mem_pestat] mean and std.dev: (1111.65, 1494.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9969)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 506, 786)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1904)
[M::mem_pestat] mean and std.dev: (434.69, 245.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2463)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 705712 reads in 195.454 CPU sec, 6.203 real sec
[M::mem_process_seqs] Processed 705934 reads in 139.360 CPU sec, 4.445 real sec
sorting block 70, #reads = 1070561 mem = 536877923 peak = 1068122112
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 282323, 48, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 435, 1229)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3281)
[M::mem_pestat] mean and std.dev: (628.18, 612.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4307)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 216, 317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 657)
[M::mem_pestat] mean and std.dev: (241.88, 121.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 827)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (377, 820, 1438)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3560)
[M::mem_pestat] mean and std.dev: (910.04, 732.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4621)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (241, 410, 1092)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2794)
[M::mem_pestat] mean and std.dev: (508.84, 441.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3645)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 707424 sequences (100000114 bp) in 2.801 CPU sec, 2.881 real sec...
[M::process] read 706274 sequences (100000179 bp) in 2.250 CPU sec, 2.244 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 283200, 51, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 332, 913)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2333)
[M::mem_pestat] mean and std.dev: (484.69, 422.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3043)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 214, 312)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 642)
[M::mem_pestat] mean and std.dev: (239.18, 119.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 807)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (311, 687, 1014)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2420)
[M::mem_pestat] mean and std.dev: (589.42, 439.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3123)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (271, 581, 1038)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2572)
[M::mem_pestat] mean and std.dev: (594.76, 393.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3339)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 707764 reads in 199.757 CPU sec, 6.315 real sec
sorting block 71, #reads = 1070907 mem = 536878520 peak = 1068122112
[M::mem_process_seqs] Processed 708216 reads in 229.258 CPU sec, 7.275 real sec
[M::process] read 705614 sequences (100000024 bp) in 2.853 CPU sec, 2.934 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 281987, 41, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (240, 413, 710)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1650)
[M::mem_pestat] mean and std.dev: (416.27, 319.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2120)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 216, 316)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 652)
[M::mem_pestat] mean and std.dev: (241.76, 121.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 820)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (240, 516, 1728)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4704)
[M::mem_pestat] mean and std.dev: (855.08, 998.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6192)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (230, 516, 1549)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4187)
[M::mem_pestat] mean and std.dev: (738.62, 669.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5506)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 707128 sequences (100000135 bp) in 2.240 CPU sec, 2.237 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (89, 281303, 39, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (260, 449, 853)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2039)
[M::mem_pestat] mean and std.dev: (575.34, 460.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2632)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 218, 319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 659)
[M::mem_pestat] mean and std.dev: (244.23, 122.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 829)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (362, 639, 1607)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4097)
[M::mem_pestat] mean and std.dev: (768.82, 723.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5342)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (236, 426, 758)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1802)
[M::mem_pestat] mean and std.dev: (442.38, 343.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2324)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 707424 reads in 207.857 CPU sec, 6.582 real sec
sorting block 72, #reads = 1071678 mem = 536879342 peak = 1068122112
[M::mem_process_seqs] Processed 706274 reads in 239.736 CPU sec, 7.619 real sec
sorting block 73, #reads = 1068819 mem = 536877415 peak = 1068122112
[M::process] read 705800 sequences (100000224 bp) in 2.577 CPU sec, 2.681 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (108, 280571, 32, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 302, 755)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1897)
[M::mem_pestat] mean and std.dev: (377.88, 332.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2468)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 220, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 666)
[M::mem_pestat] mean and std.dev: (246.26, 124.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 838)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (380, 857, 1689)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4307)
[M::mem_pestat] mean and std.dev: (1072.58, 985.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5616)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (265, 363, 905)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2185)
[M::mem_pestat] mean and std.dev: (491.57, 386.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2825)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706464 sequences (100000160 bp) in 2.116 CPU sec, 2.111 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (87, 281214, 60, 106)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 254, 580)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1396)
[M::mem_pestat] mean and std.dev: (355.35, 282.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1804)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 216, 314)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 646)
[M::mem_pestat] mean and std.dev: (241.39, 120.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 812)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 425, 1137)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3043)
[M::mem_pestat] mean and std.dev: (655.63, 675.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3996)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (255, 506, 1187)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3051)
[M::mem_pestat] mean and std.dev: (647.22, 598.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3983)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 705614 reads in 221.349 CPU sec, 7.175 real sec
[M::mem_process_seqs] Processed 707128 reads in 258.129 CPU sec, 8.381 real sec
sorting block 74, #reads = 1065809 mem = 536877805 peak = 1068122112
[M::process] read 706466 sequences (100000276 bp) in 2.951 CPU sec, 3.017 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 280664, 58, 81)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (270, 570, 1142)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2886)
[M::mem_pestat] mean and std.dev: (652.10, 487.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3758)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 217, 314)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 644)
[M::mem_pestat] mean and std.dev: (241.64, 120.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 809)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (118, 651, 1773)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5083)
[M::mem_pestat] mean and std.dev: (956.27, 1099.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6738)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 410, 813)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1985)
[M::mem_pestat] mean and std.dev: (519.61, 399.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2571)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706662 sequences (100000007 bp) in 2.320 CPU sec, 2.326 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (81, 280952, 37, 86)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 350, 957)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2479)
[M::mem_pestat] mean and std.dev: (538.34, 473.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3240)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 217, 317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 653)
[M::mem_pestat] mean and std.dev: (242.88, 121.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 821)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (112, 504, 1770)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5086)
[M::mem_pestat] mean and std.dev: (817.03, 950.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6744)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 404, 639)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1527)
[M::mem_pestat] mean and std.dev: (387.48, 295.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1971)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 706464 reads in 216.360 CPU sec, 6.849 real sec
sorting block 75, #reads = 1064572 mem = 536882326 peak = 1068122112
[M::mem_process_seqs] Processed 705800 reads in 249.860 CPU sec, 7.930 real sec
[M::process] read 712548 sequences (100000166 bp) in 2.671 CPU sec, 2.744 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 280903, 44, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 378, 804)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1992)
[M::mem_pestat] mean and std.dev: (560.38, 487.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2586)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 215, 310)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 634)
[M::mem_pestat] mean and std.dev: (238.89, 117.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 796)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (237, 463, 825)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2001)
[M::mem_pestat] mean and std.dev: (492.80, 345.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2589)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (242, 438, 815)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1961)
[M::mem_pestat] mean and std.dev: (447.49, 331.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2534)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 712652 sequences (100000149 bp) in 1.860 CPU sec, 1.866 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (74, 281010, 42, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 426, 1508)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4122)
[M::mem_pestat] mean and std.dev: (792.93, 823.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5429)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 216, 314)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 644)
[M::mem_pestat] mean and std.dev: (241.19, 120.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 809)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (296, 651, 1244)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3140)
[M::mem_pestat] mean and std.dev: (795.42, 768.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4088)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 414, 1066)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2798)
[M::mem_pestat] mean and std.dev: (615.52, 660.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3664)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 706662 reads in 225.412 CPU sec, 7.161 real sec
sorting block 76, #reads = 1065163 mem = 536878272 peak = 1068122112
[M::mem_process_seqs] Processed 706466 reads in 259.159 CPU sec, 8.247 real sec
sorting block 77, #reads = 1063392 mem = 536885835 peak = 1068122112
[M::process] read 709334 sequences (100000046 bp) in 2.941 CPU sec, 3.046 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 283348, 47, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 328, 880)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2202)
[M::mem_pestat] mean and std.dev: (481.66, 426.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2863)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (142, 206, 300)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 616)
[M::mem_pestat] mean and std.dev: (231.18, 115.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 774)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (335, 820, 7207)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 20951)
[M::mem_pestat] mean and std.dev: (2641.79, 3244.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 27823)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 351, 826)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2124)
[M::mem_pestat] mean and std.dev: (434.31, 378.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2773)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 708006 sequences (100000098 bp) in 1.820 CPU sec, 1.818 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (88, 283607, 36, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 398, 855)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2121)
[M::mem_pestat] mean and std.dev: (501.35, 383.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2754)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (142, 205, 297)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 607)
[M::mem_pestat] mean and std.dev: (228.85, 113.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 762)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (252, 979, 1116)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2844)
[M::mem_pestat] mean and std.dev: (780.97, 654.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3708)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (248, 420, 872)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2120)
[M::mem_pestat] mean and std.dev: (576.40, 499.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2744)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 712652 reads in 235.796 CPU sec, 7.508 real sec
[M::mem_process_seqs] Processed 712548 reads in 275.078 CPU sec, 8.778 real sec
sorting block 78, #reads = 1063318 mem = 536881717 peak = 1068122112
[M::process] read 706674 sequences (100000073 bp) in 2.834 CPU sec, 2.902 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 283178, 51, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 472, 1061)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2859)
[M::mem_pestat] mean and std.dev: (606.07, 585.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3758)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 212, 311)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 641)
[M::mem_pestat] mean and std.dev: (238.68, 120.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 806)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (400, 685, 1863)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4789)
[M::mem_pestat] mean and std.dev: (984.98, 924.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6252)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 309, 1053)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2739)
[M::mem_pestat] mean and std.dev: (576.64, 624.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3582)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 707418 sequences (100000091 bp) in 2.260 CPU sec, 2.261 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (96, 282458, 33, 72)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (240, 349, 741)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1743)
[M::mem_pestat] mean and std.dev: (446.08, 349.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2244)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 216, 318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 660)
[M::mem_pestat] mean and std.dev: (242.76, 122.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 831)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (537, 752, 1352)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2982)
[M::mem_pestat] mean and std.dev: (874.63, 583.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3797)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (231, 368, 1210)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3168)
[M::mem_pestat] mean and std.dev: (650.91, 621.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4147)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 709334 reads in 216.608 CPU sec, 6.860 real sec
sorting block 79, #reads = 1066154 mem = 536879221 peak = 1068122112
[M::process] read 706128 sequences (100000285 bp) in 2.373 CPU sec, 2.377 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 281701, 38, 85)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (229, 684, 1859)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5119)
[M::mem_pestat] mean and std.dev: (947.33, 895.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6749)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 219, 323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 671)
[M::mem_pestat] mean and std.dev: (246.56, 124.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 845)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (331, 535, 1375)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3463)
[M::mem_pestat] mean and std.dev: (785.61, 725.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4507)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 367, 1034)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2666)
[M::mem_pestat] mean and std.dev: (557.20, 540.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3482)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 706674 reads in 121.750 CPU sec, 3.860 real sec
[M::mem_process_seqs] Processed 708006 reads in 400.676 CPU sec, 12.745 real sec
sorting block 80, #reads = 1066236 mem = 536882472 peak = 1068122112
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 281935, 55, 80)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 365, 1248)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3308)
[M::mem_pestat] mean and std.dev: (588.10, 550.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4338)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 217, 317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 655)
[M::mem_pestat] mean and std.dev: (242.75, 122.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 824)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (276, 483, 1316)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3396)
[M::mem_pestat] mean and std.dev: (864.15, 877.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4436)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 352, 756)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1820)
[M::mem_pestat] mean and std.dev: (488.08, 411.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2352)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705316 sequences (100000169 bp) in 2.953 CPU sec, 3.072 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (91, 281161, 43, 84)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (236, 512, 1432)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3824)
[M::mem_pestat] mean and std.dev: (729.91, 771.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5020)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 219, 319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 659)
[M::mem_pestat] mean and std.dev: (244.39, 121.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 829)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (289, 600, 1200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3022)
[M::mem_pestat] mean and std.dev: (687.82, 691.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3933)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 368, 747)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1809)
[M::mem_pestat] mean and std.dev: (488.96, 412.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2340)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704748 sequences (100000006 bp) in 2.260 CPU sec, 2.263 real sec...
[M::mem_process_seqs] Processed 707418 reads in 248.313 CPU sec, 7.902 real sec
sorting block 81, #reads = 1067276 mem = 536879798 peak = 1068122112
[M::mem_process_seqs] Processed 706128 reads in 164.123 CPU sec, 5.212 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 280428, 46, 79)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (255, 386, 1101)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2793)
[M::mem_pestat] mean and std.dev: (657.34, 698.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3639)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 221, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 664)
[M::mem_pestat] mean and std.dev: (246.09, 122.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 835)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (135, 525, 932)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2526)
[M::mem_pestat] mean and std.dev: (447.08, 408.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3323)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (239, 407, 1039)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2639)
[M::mem_pestat] mean and std.dev: (646.14, 619.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3439)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704018 sequences (100000193 bp) in 3.137 CPU sec, 3.237 real sec...
[M::process] read 703714 sequences (100000021 bp) in 2.290 CPU sec, 2.298 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (80, 279937, 40, 83)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (227, 511, 1186)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3104)
[M::mem_pestat] mean and std.dev: (608.29, 563.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4063)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 222, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 661)
[M::mem_pestat] mean and std.dev: (246.30, 121.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 831)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (371, 719, 1549)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3905)
[M::mem_pestat] mean and std.dev: (881.57, 874.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5083)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 352, 726)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1776)
[M::mem_pestat] mean and std.dev: (510.44, 426.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2301)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 705316 reads in 217.945 CPU sec, 6.897 real sec
sorting block 82, #reads = 1066763 mem = 536882602 peak = 1068122112
[M::mem_process_seqs] Processed 704748 reads in 251.959 CPU sec, 8.003 real sec
sorting block 83, #reads = 1065079 mem = 536887118 peak = 1068122112
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (81, 279873, 43, 83)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (268, 384, 1505)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3979)
[M::mem_pestat] mean and std.dev: (748.86, 793.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5216)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 223, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 657)
[M::mem_pestat] mean and std.dev: (246.26, 120.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 825)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (363, 912, 1943)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5103)
[M::mem_pestat] mean and std.dev: (1292.38, 1332.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6683)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (249, 442, 761)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1785)
[M::mem_pestat] mean and std.dev: (500.47, 395.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2297)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703832 sequences (100000258 bp) in 3.108 CPU sec, 3.196 real sec...
[M::process] read 704352 sequences (100000245 bp) in 2.240 CPU sec, 2.238 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (102, 279827, 47, 79)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (244, 420, 1099)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2809)
[M::mem_pestat] mean and std.dev: (566.56, 511.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3664)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 223, 320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 654)
[M::mem_pestat] mean and std.dev: (245.81, 119.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 821)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (105, 364, 1316)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3738)
[M::mem_pestat] mean and std.dev: (772.82, 926.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4949)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 342, 1021)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2643)
[M::mem_pestat] mean and std.dev: (592.07, 614.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3454)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704018 reads in 214.912 CPU sec, 6.802 real sec
[M::mem_process_seqs] Processed 703714 reads in 255.978 CPU sec, 8.135 real sec
sorting block 84, #reads = 1064226 mem = 536876285 peak = 1068122112
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 279909, 47, 81)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 386, 1052)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2736)
[M::mem_pestat] mean and std.dev: (554.70, 484.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3578)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 222, 318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 650)
[M::mem_pestat] mean and std.dev: (244.50, 118.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 816)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (345, 1028, 1454)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3672)
[M::mem_pestat] mean and std.dev: (924.33, 756.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4781)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (287, 463, 1204)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3038)
[M::mem_pestat] mean and std.dev: (595.46, 498.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3955)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703610 sequences (100000072 bp) in 3.054 CPU sec, 3.137 real sec...
[M::process] read 704226 sequences (100000266 bp) in 2.282 CPU sec, 2.289 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 280367, 68, 74)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 338, 1125)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3035)
[M::mem_pestat] mean and std.dev: (538.78, 503.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3990)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 222, 318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 650)
[M::mem_pestat] mean and std.dev: (244.51, 118.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 816)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (354, 1669, 5638)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 16206)
[M::mem_pestat] mean and std.dev: (2671.32, 2744.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 21490)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 349, 795)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1983)
[M::mem_pestat] mean and std.dev: (518.54, 462.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2577)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703832 reads in 212.675 CPU sec, 6.740 real sec
sorting block 85, #reads = 1067581 mem = 536878410 peak = 1068122112
[M::mem_process_seqs] Processed 704352 reads in 245.387 CPU sec, 7.804 real sec
[M::process] read 703840 sequences (100000273 bp) in 2.576 CPU sec, 2.645 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (90, 280174, 32, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (228, 331, 565)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1239)
[M::mem_pestat] mean and std.dev: (359.38, 225.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1576)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 222, 319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 653)
[M::mem_pestat] mean and std.dev: (245.21, 119.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 820)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 495, 1181)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3165)
[M::mem_pestat] mean and std.dev: (649.03, 580.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4157)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 287, 638)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1550)
[M::mem_pestat] mean and std.dev: (382.78, 308.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2006)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 95774 sequences (13565803 bp) in 0.509 CPU sec, 0.511 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (91, 280309, 47, 77)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (252, 572, 1222)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3162)
[M::mem_pestat] mean and std.dev: (608.01, 484.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4132)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 222, 319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 653)
[M::mem_pestat] mean and std.dev: (244.84, 119.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 820)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (225, 695, 1477)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3981)
[M::mem_pestat] mean and std.dev: (995.76, 1078.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5309)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 350, 658)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1540)
[M::mem_pestat] mean and std.dev: (410.38, 282.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1981)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703610 reads in 208.903 CPU sec, 6.678 real sec
sorting block 86, #reads = 1066706 mem = 536879498 peak = 1068122112
[M::mem_process_seqs] Processed 704226 reads in 241.306 CPU sec, 7.740 real sec
sorting block 87, #reads = 1068007 mem = 536885727 peak = 1068122112
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (80, 280190, 40, 81)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 358, 980)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2542)
[M::mem_pestat] mean and std.dev: (575.36, 542.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3323)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 223, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 657)
[M::mem_pestat] mean and std.dev: (246.31, 121.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 825)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (305, 1028, 1559)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4067)
[M::mem_pestat] mean and std.dev: (965.64, 754.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5321)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 462, 1536)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4234)
[M::mem_pestat] mean and std.dev: (811.78, 914.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5583)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (2, 38202, 4, 10)
[M::mem_pestat] skip orientation FF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 218, 316)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 648)
[M::mem_pestat] mean and std.dev: (242.55, 119.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 814)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 216, 431)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 943)
[M::mem_pestat] mean and std.dev: (253.33, 109.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1199)
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703840 reads in 133.563 CPU sec, 4.320 real sec
[M::mem_process_seqs] Processed 95774 reads in 48.784 CPU sec, 1.580 real sec
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000c06f2
  features: bfebfbff 7ffefbff
  extended: f3bfb7ef fb417ffe
  amd bits: 2c100800 00000121
     brand: INTEL(R) XEON(R) PLATINUM 8559C
threads: 31
algo: bwa-mem
license: sentieon:klib=31
reads: 94045206
overall: 70727753728 mem 18193.972 user 522.102 sys 642.134 real
[main] Version: 0.7.17-r1188
[main] CMD: /opt/conda/share/sentieon-202308.03-3/libexec/bwa mem -K 100000000 -Y -R @RG\tID:A23MHWWLT4.1136_3WJ-T1-TDNA-1_A23MHWWLT4_1.L001\tPU:L001\tSM:1136_3WJ-T1-TDNA-1_A23MHWWLT4_1\tLB:1136_3WJ-T1-TDNA-1_A23MHWWLT4_1\tDS:s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta\tPL:ILLUMINA -t 31 ./BWAIndex/Homo_sapiens_assembly38.fasta.64 1136_3WJ-T1-TDNA-1_A23MHWWLT4_1_R1.fastq.gz 1136_3WJ-T1-TDNA-1_A23MHWWLT4_1_R2.fastq.gz
[main] Real time: 642.166 sec; CPU: 18716.077 sec
sorting block 88, #reads = 939945 mem = 473622978 peak = 1068122112
uniq header count 1
merging 89 blocks
sw version: sentieon-genomics-202308.03
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000c06f2
  features: bfebfbff 7ffefbff
  extended: f3bfb7ef fb417ffe
  amd bits: 2c100800 00000121
     brand: INTEL(R) XEON(R) PLATINUM 8559C
threads: 31 max 192
algo: util-sort
license: sentieon:util=1
output file size: 5486604833
output reads: 94942199
bam_mem_sort: 89 calls 57.306 user 2.065 sys 59.810 real
bam_write: 89 calls 40.015 user 3.203 sys 57.876 real
execute: 1 calls 33.990 user 2.012 sys 685.896 real
merge_files: 1 calls 33.963 user 1.965 sys 43.073 real
parse_chunk: 1423 calls 77.485 user 20.434 sys 102.319 real
read_chunk: 3856 calls 49.565 user 29.283 sys 548.869 real
sort_block: 1 calls 32.680 user 28.566 sys 526.840 real
write_chunk: 2431 calls 33.419 user 1.532 sys 41.757 real
overall: 3392491520 mem 1664.508 user 75.256 sys 685.919 real
ls: cannot access '*.cram': No such file or directory