This software is licensed to bgold@natera.com by Sentieon Inc.
cmdline: /opt/conda/share/sentieon-202308.03-3/libexec/util sort -r Homo_sapiens_assembly38.fasta -t 31 -o 1029_BICJ-T1-TDNA-1_A23MHWWLT4_1.bam --sam2bam -
This software is licensed to bgold@natera.com by Sentieon Inc.
version: sentieon-genomics-202308.03
[M::bwa_idx_load_from_disk] read 3171 ALT contigs
[M::main_mem] bwa index loaded in 1645.823 CPU sec, 58.780 real sec
[M::process] read 724520 sequences (100000062 bp) in 1.289 CPU sec, 1.294 real sec...
[M::process] read 720768 sequences (100000158 bp) in 1.449 CPU sec, 1.451 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (113, 286893, 72, 108)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 702, 1642)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4592)
[M::mem_pestat] mean and std.dev: (932.44, 953.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6067)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 184, 261)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 521)
[M::mem_pestat] mean and std.dev: (203.40, 94.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 651)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 390, 1111)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2957)
[M::mem_pestat] mean and std.dev: (619.68, 601.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3880)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (248, 477, 1024)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2576)
[M::mem_pestat] mean and std.dev: (664.58, 569.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3352)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723480 sequences (100000050 bp) in 1.587 CPU sec, 1.733 real sec...
[M::process] read 725204 sequences (100000017 bp) in 1.565 CPU sec, 1.664 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (109, 285367, 62, 93)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 429, 968)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2522)
[M::mem_pestat] mean and std.dev: (562.01, 560.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3299)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 188, 269)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 539)
[M::mem_pestat] mean and std.dev: (208.77, 98.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 674)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 599, 1326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3582)
[M::mem_pestat] mean and std.dev: (837.72, 800.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4710)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 373, 1066)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2836)
[M::mem_pestat] mean and std.dev: (610.96, 586.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3721)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 724520 reads in 193.970 CPU sec, 6.460 real sec
[M::mem_process_seqs] Processed 720768 reads in 136.899 CPU sec, 4.770 real sec
sorting block 0, #reads = 1076556 mem = 536879777 peak = 583200768
[M::process] read 725758 sequences (100000107 bp) in 2.060 CPU sec, 2.130 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (113, 286848, 73, 91)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (293, 609, 1134)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2816)
[M::mem_pestat] mean and std.dev: (684.99, 502.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3657)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 185, 263)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 525)
[M::mem_pestat] mean and std.dev: (205.00, 95.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 656)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (339, 610, 1349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3369)
[M::mem_pestat] mean and std.dev: (776.32, 727.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4379)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 368, 720)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1740)
[M::mem_pestat] mean and std.dev: (476.48, 383.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2250)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722228 sequences (100000045 bp) in 1.920 CPU sec, 1.926 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (91, 287357, 56, 95)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 329, 797)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2007)
[M::mem_pestat] mean and std.dev: (456.12, 423.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2612)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 182, 257)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 511)
[M::mem_pestat] mean and std.dev: (200.75, 92.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 638)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 450, 1829)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5171)
[M::mem_pestat] mean and std.dev: (959.04, 1109.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6842)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 319, 683)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1689)
[M::mem_pestat] mean and std.dev: (388.61, 340.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2192)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (109, 287040, 59, 96)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (229, 613, 1182)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3088)
[M::mem_pestat] mean and std.dev: (756.70, 644.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4041)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 183, 259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 517)
[M::mem_pestat] mean and std.dev: (202.07, 94.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 646)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 426, 1719)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4797)
[M::mem_pestat] mean and std.dev: (709.08, 855.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6336)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (238, 411, 915)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2269)
[M::mem_pestat] mean and std.dev: (532.22, 404.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2946)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 723480 reads in 260.055 CPU sec, 8.460 real sec
sorting block 1, #reads = 1078271 mem = 536880763 peak = 740487168
[M::mem_process_seqs] Processed 725758 reads in 204.079 CPU sec, 6.713 real sec
[M::mem_process_seqs] Processed 725204 reads in 230.231 CPU sec, 7.563 real sec
sorting block 2, #reads = 1078928 mem = 536882453 peak = 740487168
[M::process] read 723766 sequences (100000288 bp) in 2.363 CPU sec, 2.439 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (92, 286686, 90, 99)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (286, 476, 1026)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2506)
[M::mem_pestat] mean and std.dev: (616.66, 470.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3246)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 187, 267)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 535)
[M::mem_pestat] mean and std.dev: (207.66, 98.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 669)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (69, 282, 992)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2838)
[M::mem_pestat] mean and std.dev: (521.17, 677.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3761)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 512, 753)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1845)
[M::mem_pestat] mean and std.dev: (481.52, 339.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2391)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725546 sequences (100000104 bp) in 2.005 CPU sec, 2.018 real sec...
[M::process] read 724838 sequences (100000083 bp) in 1.600 CPU sec, 1.660 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (92, 286717, 82, 106)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 378, 893)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2293)
[M::mem_pestat] mean and std.dev: (560.73, 538.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2993)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 184, 261)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 519)
[M::mem_pestat] mean and std.dev: (203.93, 95.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 648)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (228, 576, 898)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2238)
[M::mem_pestat] mean and std.dev: (614.66, 549.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2908)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 394, 1621)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4453)
[M::mem_pestat] mean and std.dev: (879.92, 944.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5869)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 722228 reads in 194.750 CPU sec, 6.201 real sec
sorting block 3, #reads = 1077669 mem = 536880886 peak = 763674624
[M::process] read 724504 sequences (100000159 bp) in 1.895 CPU sec, 1.905 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (109, 287438, 59, 79)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 439, 1117)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3003)
[M::mem_pestat] mean and std.dev: (602.03, 525.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3946)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 182, 258)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 514)
[M::mem_pestat] mean and std.dev: (201.40, 93.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 642)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (127, 277, 1281)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3589)
[M::mem_pestat] mean and std.dev: (717.38, 885.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4743)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 423, 835)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2083)
[M::mem_pestat] mean and std.dev: (466.29, 369.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2707)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 725546 reads in 108.737 CPU sec, 3.457 real sec
[M::mem_process_seqs] Processed 723766 reads in 267.705 CPU sec, 8.549 real sec
sorting block 4, #reads = 1079964 mem = 536876496 peak = 763674624
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (105, 287673, 55, 105)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 382, 998)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2562)
[M::mem_pestat] mean and std.dev: (631.42, 630.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3344)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 183, 259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 515)
[M::mem_pestat] mean and std.dev: (202.21, 93.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 643)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 760, 1654)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4580)
[M::mem_pestat] mean and std.dev: (941.94, 886.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6043)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (254, 475, 863)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2081)
[M::mem_pestat] mean and std.dev: (556.60, 413.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2690)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720310 sequences (100000260 bp) in 2.313 CPU sec, 2.379 real sec...
[M::process] read 723008 sequences (100000118 bp) in 1.620 CPU sec, 1.625 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (84, 287044, 85, 73)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 507, 1235)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3279)
[M::mem_pestat] mean and std.dev: (683.63, 670.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4301)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 183, 258)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 512)
[M::mem_pestat] mean and std.dev: (201.75, 93.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 639)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (91, 413, 909)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2545)
[M::mem_pestat] mean and std.dev: (453.59, 439.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3363)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 588, 1183)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3103)
[M::mem_pestat] mean and std.dev: (731.68, 680.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4063)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 724838 reads in 296.530 CPU sec, 9.428 real sec
sorting block 5, #reads = 1079437 mem = 536894055 peak = 763674624
[M::mem_process_seqs] Processed 724504 reads in 128.506 CPU sec, 4.099 real sec
[M::process] read 721370 sequences (100000047 bp) in 2.528 CPU sec, 2.597 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (96, 285032, 79, 131)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 363, 839)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2167)
[M::mem_pestat] mean and std.dev: (511.16, 474.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2831)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 188, 267)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 533)
[M::mem_pestat] mean and std.dev: (208.14, 97.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 666)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 627, 1092)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2910)
[M::mem_pestat] mean and std.dev: (721.71, 655.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3819)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (239, 566, 1253)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3281)
[M::mem_pestat] mean and std.dev: (737.23, 643.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4295)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722702 sequences (100000184 bp) in 2.020 CPU sec, 2.014 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (102, 286469, 81, 98)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 440, 857)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2177)
[M::mem_pestat] mean and std.dev: (534.12, 464.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2837)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 184, 260)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 516)
[M::mem_pestat] mean and std.dev: (203.21, 93.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 644)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 555, 1174)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3136)
[M::mem_pestat] mean and std.dev: (654.49, 583.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4117)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 355, 844)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2132)
[M::mem_pestat] mean and std.dev: (524.13, 465.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2776)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 720310 reads in 193.171 CPU sec, 6.130 real sec
sorting block 6, #reads = 1077749 mem = 536881273 peak = 777818112
[M::mem_process_seqs] Processed 723008 reads in 135.687 CPU sec, 4.337 real sec
sorting block 7, #reads = 1074936 mem = 536876725 peak = 839864320
[M::process] read 722070 sequences (100000097 bp) in 2.352 CPU sec, 2.426 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (109, 286190, 79, 107)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (229, 462, 943)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2371)
[M::mem_pestat] mean and std.dev: (578.21, 492.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3085)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 187, 264)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 526)
[M::mem_pestat] mean and std.dev: (206.23, 95.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 657)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 501, 1232)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3234)
[M::mem_pestat] mean and std.dev: (718.43, 718.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4235)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 548, 1533)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4173)
[M::mem_pestat] mean and std.dev: (914.80, 911.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5493)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720606 sequences (100000153 bp) in 1.860 CPU sec, 1.866 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (94, 286304, 73, 93)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 365, 774)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1890)
[M::mem_pestat] mean and std.dev: (428.23, 315.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2448)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 185, 261)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 517)
[M::mem_pestat] mean and std.dev: (204.00, 93.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 645)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (273, 634, 1787)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4815)
[M::mem_pestat] mean and std.dev: (993.48, 974.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6329)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 327, 859)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2185)
[M::mem_pestat] mean and std.dev: (498.15, 461.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2848)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (101, 286161, 65, 114)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (314, 616, 1089)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2639)
[M::mem_pestat] mean and std.dev: (703.91, 576.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3414)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 185, 261)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 519)
[M::mem_pestat] mean and std.dev: (204.04, 93.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 648)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (273, 663, 1327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3435)
[M::mem_pestat] mean and std.dev: (863.68, 807.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4489)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 435, 869)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2119)
[M::mem_pestat] mean and std.dev: (530.16, 434.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2744)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 721370 reads in 270.079 CPU sec, 8.625 real sec
[M::mem_process_seqs] Processed 722070 reads in 213.666 CPU sec, 6.875 real sec
[M::mem_process_seqs] Processed 722702 reads in 240.564 CPU sec, 7.765 real sec
sorting block 8, #reads = 1075834 mem = 536879868 peak = 839864320
[M::process] read 721420 sequences (100000161 bp) in 2.966 CPU sec, 3.101 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (94, 285220, 62, 94)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (234, 672, 1291)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3405)
[M::mem_pestat] mean and std.dev: (765.71, 641.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4462)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 188, 267)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 533)
[M::mem_pestat] mean and std.dev: (207.57, 96.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 666)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 614, 1852)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5206)
[M::mem_pestat] mean and std.dev: (1010.41, 1234.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6883)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 441, 957)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2433)
[M::mem_pestat] mean and std.dev: (593.90, 487.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3171)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 9, #reads = 1077085 mem = 536879497 peak = 839864320
[M::process] read 722954 sequences (100000087 bp) in 2.431 CPU sec, 2.464 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (100, 285798, 61, 103)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 458, 1157)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3045)
[M::mem_pestat] mean and std.dev: (607.45, 585.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3989)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 187, 264)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 526)
[M::mem_pestat] mean and std.dev: (206.05, 95.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 657)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 607, 1606)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4494)
[M::mem_pestat] mean and std.dev: (889.83, 954.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5938)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (280, 349, 999)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2437)
[M::mem_pestat] mean and std.dev: (546.24, 482.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3156)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 720606 reads in 198.203 CPU sec, 6.305 real sec
[M::mem_process_seqs] Processed 721420 reads in 140.379 CPU sec, 4.417 real sec
[M::process] read 721456 sequences (100000083 bp) in 2.022 CPU sec, 2.072 real sec...
sorting block 10, #reads = 1076179 mem = 536878862 peak = 839864320
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (82, 286353, 73, 98)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 412, 1319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3601)
[M::mem_pestat] mean and std.dev: (763.26, 900.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4742)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 185, 260)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 516)
[M::mem_pestat] mean and std.dev: (203.30, 93.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 644)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 512, 1526)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4160)
[M::mem_pestat] mean and std.dev: (725.58, 662.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5477)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (237, 381, 920)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2286)
[M::mem_pestat] mean and std.dev: (560.83, 510.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2969)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722894 sequences (100000217 bp) in 2.756 CPU sec, 2.833 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (102, 285566, 84, 99)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 463, 1213)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3277)
[M::mem_pestat] mean and std.dev: (670.11, 639.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4309)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 187, 265)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 529)
[M::mem_pestat] mean and std.dev: (206.57, 95.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 661)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 640, 1815)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5035)
[M::mem_pestat] mean and std.dev: (1143.43, 1271.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6645)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 412, 626)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1460)
[M::mem_pestat] mean and std.dev: (382.36, 253.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1877)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722998 sequences (100000253 bp) in 2.090 CPU sec, 2.096 real sec...
[M::mem_process_seqs] Processed 722954 reads in 186.034 CPU sec, 5.896 real sec
sorting block 11, #reads = 1076216 mem = 536880997 peak = 864124928
[M::mem_process_seqs] Processed 721456 reads in 131.021 CPU sec, 4.152 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (141, 285928, 85, 121)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 448, 1022)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2642)
[M::mem_pestat] mean and std.dev: (641.27, 606.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3452)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 184, 261)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 519)
[M::mem_pestat] mean and std.dev: (203.36, 93.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 648)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (130, 417, 1098)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3034)
[M::mem_pestat] mean and std.dev: (563.63, 586.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4002)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (255, 435, 826)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1968)
[M::mem_pestat] mean and std.dev: (531.84, 388.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2539)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 721736 sequences (100000180 bp) in 2.464 CPU sec, 2.567 real sec...
[M::process] read 724326 sequences (100000109 bp) in 2.280 CPU sec, 2.289 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (85, 287123, 66, 118)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 359, 695)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1687)
[M::mem_pestat] mean and std.dev: (473.30, 410.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2183)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 185, 263)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 525)
[M::mem_pestat] mean and std.dev: (204.84, 95.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 656)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 754, 1920)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5438)
[M::mem_pestat] mean and std.dev: (916.44, 953.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7197)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 518, 1187)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3135)
[M::mem_pestat] mean and std.dev: (688.95, 649.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4109)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 722894 reads in 201.255 CPU sec, 6.383 real sec
sorting block 12, #reads = 1076918 mem = 536878599 peak = 864124928
[M::process] read 722612 sequences (100000032 bp) in 2.558 CPU sec, 2.562 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (107, 285699, 71, 89)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 370, 758)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1928)
[M::mem_pestat] mean and std.dev: (440.20, 342.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2513)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 187, 266)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 532)
[M::mem_pestat] mean and std.dev: (207.09, 96.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 665)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (238, 475, 1181)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3067)
[M::mem_pestat] mean and std.dev: (662.05, 583.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4010)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (265, 617, 1255)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3235)
[M::mem_pestat] mean and std.dev: (875.79, 814.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4225)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 721736 reads in 117.323 CPU sec, 3.711 real sec
sorting block 13, #reads = 1075861 mem = 536880377 peak = 933683200
[M::mem_process_seqs] Processed 722998 reads in 301.142 CPU sec, 9.604 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (110, 286928, 60, 105)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (239, 545, 988)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2486)
[M::mem_pestat] mean and std.dev: (651.93, 512.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3235)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 183, 260)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 518)
[M::mem_pestat] mean and std.dev: (202.77, 94.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 647)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 507, 705)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1739)
[M::mem_pestat] mean and std.dev: (473.61, 362.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2256)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (247, 459, 919)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2263)
[M::mem_pestat] mean and std.dev: (510.88, 387.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2935)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724530 sequences (100000034 bp) in 2.892 CPU sec, 2.985 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (78, 286762, 63, 95)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 408, 845)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2221)
[M::mem_pestat] mean and std.dev: (552.31, 538.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2909)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 186, 266)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 534)
[M::mem_pestat] mean and std.dev: (206.81, 97.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 668)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (292, 602, 1248)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3160)
[M::mem_pestat] mean and std.dev: (776.69, 777.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4116)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (232, 450, 1221)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3199)
[M::mem_pestat] mean and std.dev: (743.75, 680.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4188)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723528 sequences (100000081 bp) in 2.240 CPU sec, 2.238 real sec...
[M::mem_process_seqs] Processed 724326 reads in 236.609 CPU sec, 7.508 real sec
sorting block 14, #reads = 1078571 mem = 536883941 peak = 933683200
[M::mem_process_seqs] Processed 722612 reads in 145.546 CPU sec, 4.609 real sec
sorting block 15, #reads = 1079819 mem = 536877959 peak = 933683200
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 286547, 52, 77)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 422, 845)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2099)
[M::mem_pestat] mean and std.dev: (489.39, 415.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2726)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 184, 262)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 524)
[M::mem_pestat] mean and std.dev: (204.29, 95.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 655)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (124, 406, 1129)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3139)
[M::mem_pestat] mean and std.dev: (564.86, 556.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4144)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (326, 761, 1236)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3056)
[M::mem_pestat] mean and std.dev: (776.83, 616.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3966)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724436 sequences (100000053 bp) in 3.057 CPU sec, 3.170 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (120, 287467, 109, 106)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 287, 609)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1447)
[M::mem_pestat] mean and std.dev: (345.84, 252.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1866)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 185, 264)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 528)
[M::mem_pestat] mean and std.dev: (205.37, 96.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 660)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 539, 1158)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3102)
[M::mem_pestat] mean and std.dev: (562.31, 648.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4074)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (251, 477, 1306)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3416)
[M::mem_pestat] mean and std.dev: (730.50, 645.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4471)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723058 sequences (100000221 bp) in 2.310 CPU sec, 2.305 real sec...
[M::mem_process_seqs] Processed 724530 reads in 203.436 CPU sec, 6.438 real sec
[M::mem_process_seqs] Processed 723528 reads in 140.665 CPU sec, 4.472 real sec
sorting block 16, #reads = 1078541 mem = 536881541 peak = 933683200
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (109, 287295, 79, 97)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 440, 996)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2608)
[M::mem_pestat] mean and std.dev: (632.72, 590.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3414)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 184, 261)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 521)
[M::mem_pestat] mean and std.dev: (203.50, 94.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 651)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (232, 378, 1411)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3769)
[M::mem_pestat] mean and std.dev: (849.05, 852.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4948)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (284, 478, 1010)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2462)
[M::mem_pestat] mean and std.dev: (688.44, 610.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3188)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724064 sequences (100000149 bp) in 2.706 CPU sec, 2.806 real sec...
[M::process] read 724802 sequences (100000013 bp) in 1.890 CPU sec, 1.894 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (82, 286876, 70, 100)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 377, 833)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2089)
[M::mem_pestat] mean and std.dev: (498.04, 433.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2717)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 186, 265)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 531)
[M::mem_pestat] mean and std.dev: (206.32, 96.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 664)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 759, 1946)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5402)
[M::mem_pestat] mean and std.dev: (1174.75, 1347.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7130)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (297, 662, 1070)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2616)
[M::mem_pestat] mean and std.dev: (653.85, 474.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3389)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 724436 reads in 203.393 CPU sec, 6.456 real sec
sorting block 17, #reads = 1080034 mem = 536881376 peak = 933683200
[M::mem_process_seqs] Processed 723058 reads in 144.938 CPU sec, 4.612 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (77, 287302, 61, 95)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (260, 388, 1255)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3245)
[M::mem_pestat] mean and std.dev: (737.46, 723.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4240)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 184, 261)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 521)
[M::mem_pestat] mean and std.dev: (203.07, 94.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 651)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (245, 578, 1206)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3128)
[M::mem_pestat] mean and std.dev: (681.07, 601.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4089)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 367, 900)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2308)
[M::mem_pestat] mean and std.dev: (539.46, 428.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3012)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723552 sequences (100000218 bp) in 2.981 CPU sec, 3.081 real sec...
[M::process] read 723288 sequences (100000131 bp) in 2.300 CPU sec, 2.300 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (102, 287302, 73, 107)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (298, 542, 1118)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2758)
[M::mem_pestat] mean and std.dev: (512.47, 381.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3578)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 185, 263)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 525)
[M::mem_pestat] mean and std.dev: (204.69, 95.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 656)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 514, 981)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2503)
[M::mem_pestat] mean and std.dev: (583.39, 548.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3264)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 565, 1106)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2860)
[M::mem_pestat] mean and std.dev: (685.40, 552.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3737)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 724802 reads in 204.322 CPU sec, 6.468 real sec
sorting block 18, #reads = 1078262 mem = 536883607 peak = 933683200
[M::mem_process_seqs] Processed 724064 reads in 233.181 CPU sec, 7.413 real sec
sorting block 19, #reads = 1080010 mem = 536877264 peak = 997646336
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (124, 287128, 67, 98)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 261, 678)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1678)
[M::mem_pestat] mean and std.dev: (409.10, 361.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2178)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 185, 263)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 525)
[M::mem_pestat] mean and std.dev: (204.60, 95.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 656)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (257, 629, 1123)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2855)
[M::mem_pestat] mean and std.dev: (701.70, 645.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3721)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (243, 751, 1661)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4497)
[M::mem_pestat] mean and std.dev: (922.87, 909.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5915)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 719554 sequences (100000244 bp) in 2.957 CPU sec, 3.070 real sec...
[M::process] read 722380 sequences (100000058 bp) in 1.940 CPU sec, 1.936 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (120, 286918, 60, 108)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (236, 424, 1186)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3086)
[M::mem_pestat] mean and std.dev: (637.27, 603.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4036)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 185, 262)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 522)
[M::mem_pestat] mean and std.dev: (204.30, 94.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 652)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 306, 682)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1632)
[M::mem_pestat] mean and std.dev: (404.08, 370.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2107)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (262, 512, 1152)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2932)
[M::mem_pestat] mean and std.dev: (656.41, 684.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3822)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 723552 reads in 203.668 CPU sec, 6.459 real sec
[M::mem_process_seqs] Processed 723288 reads in 142.019 CPU sec, 4.534 real sec
sorting block 20, #reads = 1078322 mem = 536884558 peak = 997646336
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (95, 285363, 70, 100)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 432, 1029)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2731)
[M::mem_pestat] mean and std.dev: (598.38, 525.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3582)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 191, 272)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 546)
[M::mem_pestat] mean and std.dev: (211.07, 99.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 683)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 552, 1105)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3015)
[M::mem_pestat] mean and std.dev: (568.78, 540.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3970)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (239, 595, 1800)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4922)
[M::mem_pestat] mean and std.dev: (983.54, 1000.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6483)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722754 sequences (100000277 bp) in 3.077 CPU sec, 3.150 real sec...
[M::process] read 723632 sequences (100000245 bp) in 2.307 CPU sec, 2.315 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (89, 285656, 86, 103)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 493, 1741)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4819)
[M::mem_pestat] mean and std.dev: (887.95, 1033.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6358)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 186, 263)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 525)
[M::mem_pestat] mean and std.dev: (205.20, 95.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 656)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 519, 1332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3656)
[M::mem_pestat] mean and std.dev: (762.23, 756.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4818)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (233, 402, 875)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2159)
[M::mem_pestat] mean and std.dev: (559.85, 438.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2801)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 719554 reads in 207.860 CPU sec, 6.579 real sec
sorting block 21, #reads = 1077356 mem = 536880154 peak = 997646336
[M::process] read 723058 sequences (100000276 bp) in 2.510 CPU sec, 2.518 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (102, 286781, 67, 87)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 384, 1076)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2836)
[M::mem_pestat] mean and std.dev: (596.27, 619.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3716)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 185, 262)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 522)
[M::mem_pestat] mean and std.dev: (204.46, 94.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 652)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 446, 1064)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2820)
[M::mem_pestat] mean and std.dev: (574.10, 580.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3698)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (291, 525, 1168)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2922)
[M::mem_pestat] mean and std.dev: (615.52, 601.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3799)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 722754 reads in 121.722 CPU sec, 4.000 real sec
sorting block 22, #reads = 1076871 mem = 536888687 peak = 997646336
[M::mem_process_seqs] Processed 722380 reads in 304.414 CPU sec, 9.821 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (111, 286410, 53, 99)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 441, 1387)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3769)
[M::mem_pestat] mean and std.dev: (806.64, 789.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4960)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 184, 259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 515)
[M::mem_pestat] mean and std.dev: (202.62, 93.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 643)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 450, 1657)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4549)
[M::mem_pestat] mean and std.dev: (773.06, 911.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5995)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 345, 1023)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2685)
[M::mem_pestat] mean and std.dev: (634.22, 654.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3516)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720408 sequences (100000234 bp) in 2.921 CPU sec, 3.223 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (134, 286866, 82, 115)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 306, 643)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1589)
[M::mem_pestat] mean and std.dev: (381.60, 296.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2062)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 184, 261)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 519)
[M::mem_pestat] mean and std.dev: (203.32, 93.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 648)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 854, 1188)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3168)
[M::mem_pestat] mean and std.dev: (780.92, 651.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4158)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (242, 414, 1100)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2816)
[M::mem_pestat] mean and std.dev: (592.49, 601.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3674)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 723632 reads in 238.449 CPU sec, 7.565 real sec
[M::process] read 722110 sequences (100000199 bp) in 2.290 CPU sec, 2.286 real sec...
sorting block 23, #reads = 1075604 mem = 536877946 peak = 997646336
[M::mem_process_seqs] Processed 723058 reads in 148.628 CPU sec, 4.696 real sec
sorting block 24, #reads = 1077788 mem = 536877181 peak = 997646336
[M::process] read 723142 sequences (100000043 bp) in 3.156 CPU sec, 3.281 real sec...
[M::process] read 722912 sequences (100000119 bp) in 2.119 CPU sec, 2.123 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (93, 286030, 93, 89)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 354, 903)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2369)
[M::mem_pestat] mean and std.dev: (490.21, 480.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3102)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 186, 263)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 523)
[M::mem_pestat] mean and std.dev: (205.12, 94.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 653)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 471, 1124)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2994)
[M::mem_pestat] mean and std.dev: (659.36, 731.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3929)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 320, 732)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1770)
[M::mem_pestat] mean and std.dev: (416.32, 295.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2289)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 722110 reads in 117.740 CPU sec, 3.777 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (97, 285105, 86, 92)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 408, 770)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1848)
[M::mem_pestat] mean and std.dev: (475.85, 342.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2387)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 188, 267)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 533)
[M::mem_pestat] mean and std.dev: (207.83, 96.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 666)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (142, 421, 1096)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3004)
[M::mem_pestat] mean and std.dev: (591.84, 685.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3958)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 314, 829)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2093)
[M::mem_pestat] mean and std.dev: (480.69, 427.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2725)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (108, 286381, 68, 97)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (232, 496, 979)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2473)
[M::mem_pestat] mean and std.dev: (638.37, 497.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3220)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 185, 261)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 519)
[M::mem_pestat] mean and std.dev: (203.61, 93.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 648)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (133, 463, 1693)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4813)
[M::mem_pestat] mean and std.dev: (985.04, 1191.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6373)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (267, 391, 1161)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2949)
[M::mem_pestat] mean and std.dev: (636.78, 555.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3843)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723632 sequences (100000289 bp) in 2.061 CPU sec, 2.066 real sec...
[M::mem_process_seqs] Processed 720408 reads in 323.788 CPU sec, 10.324 real sec
sorting block 25, #reads = 1075746 mem = 536879029 peak = 997646336
[M::mem_process_seqs] Processed 723142 reads in 182.524 CPU sec, 5.914 real sec
sorting block 26, #reads = 1074867 mem = 536881959 peak = 997646336
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (96, 285870, 52, 131)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (233, 403, 980)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2474)
[M::mem_pestat] mean and std.dev: (576.75, 517.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3221)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 185, 261)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 519)
[M::mem_pestat] mean and std.dev: (203.58, 93.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 648)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (93, 344, 915)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2559)
[M::mem_pestat] mean and std.dev: (407.70, 397.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3381)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (273, 607, 1193)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3033)
[M::mem_pestat] mean and std.dev: (756.63, 667.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3953)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723904 sequences (100000158 bp) in 2.938 CPU sec, 3.059 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (93, 286435, 58, 98)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 441, 1050)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2752)
[M::mem_pestat] mean and std.dev: (593.16, 540.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3603)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::process] read 724014 sequences (100000096 bp) in 2.349 CPU sec, 2.347 real sec...
[M::mem_pestat] (25, 50, 75) percentile: (131, 184, 260)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 518)
[M::mem_pestat] mean and std.dev: (203.03, 93.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 647)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (356, 543, 1080)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2528)
[M::mem_pestat] mean and std.dev: (638.13, 457.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3252)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 414, 1047)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2731)
[M::mem_pestat] mean and std.dev: (663.74, 659.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3573)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 722912 reads in 210.770 CPU sec, 6.678 real sec
[M::mem_process_seqs] Processed 723632 reads in 154.212 CPU sec, 4.907 real sec
sorting block 27, #reads = 1075951 mem = 536879168 peak = 997646336
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (97, 285411, 102, 117)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 348, 848)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2154)
[M::mem_pestat] mean and std.dev: (483.69, 428.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2807)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 184, 260)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 518)
[M::mem_pestat] mean and std.dev: (202.91, 93.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 647)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (252, 504, 1087)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2757)
[M::mem_pestat] mean and std.dev: (521.90, 555.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3592)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (243, 375, 1020)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2574)
[M::mem_pestat] mean and std.dev: (609.04, 511.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3351)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724534 sequences (100000133 bp) in 3.697 CPU sec, 3.847 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (90, 286986, 85, 79)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (260, 680, 1240)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3200)
[M::mem_pestat] mean and std.dev: (803.51, 714.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4180)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 183, 260)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 518)
[M::mem_pestat] mean and std.dev: (202.68, 93.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 647)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 557, 1363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3677)
[M::mem_pestat] mean and std.dev: (688.22, 581.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4834)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 450, 1267)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3357)
[M::mem_pestat] mean and std.dev: (621.84, 649.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4402)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724516 sequences (100000117 bp) in 2.450 CPU sec, 2.447 real sec...
[M::mem_process_seqs] Processed 723904 reads in 221.901 CPU sec, 7.018 real sec
sorting block 28, #reads = 1075194 mem = 536880552 peak = 997646336
[M::mem_process_seqs] Processed 724014 reads in 156.841 CPU sec, 4.985 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (100, 286206, 70, 121)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 358, 1253)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3367)
[M::mem_pestat] mean and std.dev: (625.06, 579.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4424)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 184, 261)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 521)
[M::mem_pestat] mean and std.dev: (203.14, 94.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 651)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (102, 541, 889)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2463)
[M::mem_pestat] mean and std.dev: (543.98, 492.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3250)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (257, 579, 1580)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4226)
[M::mem_pestat] mean and std.dev: (783.18, 708.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5549)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723328 sequences (100000248 bp) in 3.089 CPU sec, 3.205 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (90, 287370, 68, 93)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 394, 1503)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4117)
[M::mem_pestat] mean and std.dev: (767.95, 863.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5424)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 184, 261)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 521)
[M::mem_pestat] mean and std.dev: (203.17, 94.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 651)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 594, 927)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2403)
[M::mem_pestat] mean and std.dev: (664.16, 621.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3150)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 332, 813)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1985)
[M::mem_pestat] mean and std.dev: (481.93, 446.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2571)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723442 sequences (100000204 bp) in 2.450 CPU sec, 2.448 real sec...
[M::mem_process_seqs] Processed 724534 reads in 218.436 CPU sec, 6.924 real sec
sorting block 29, #reads = 1075309 mem = 536877590 peak = 997646336
[M::mem_process_seqs] Processed 724516 reads in 153.551 CPU sec, 4.878 real sec
sorting block 30, #reads = 1077662 mem = 536879437 peak = 1008168960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (94, 286801, 100, 105)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 451, 1097)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2847)
[M::mem_pestat] mean and std.dev: (643.01, 542.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3722)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 185, 263)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 525)
[M::mem_pestat] mean and std.dev: (204.97, 95.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 656)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (561, 1051, 2065)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5073)
[M::mem_pestat] mean and std.dev: (1257.00, 961.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6577)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 374, 700)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1668)
[M::mem_pestat] mean and std.dev: (409.92, 269.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2152)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720126 sequences (100000298 bp) in 3.086 CPU sec, 3.207 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (111, 286290, 65, 111)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (290, 416, 869)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2027)
[M::mem_pestat] mean and std.dev: (573.17, 402.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2606)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 186, 265)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 531)
[M::mem_pestat] mean and std.dev: (206.17, 97.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 664)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (308, 454, 860)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1964)
[M::mem_pestat] mean and std.dev: (566.57, 460.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2516)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (290, 461, 1071)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2633)
[M::mem_pestat] mean and std.dev: (607.59, 498.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3414)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724616 sequences (100000118 bp) in 2.547 CPU sec, 2.555 real sec...
[M::mem_process_seqs] Processed 723328 reads in 213.996 CPU sec, 6.776 real sec
[M::mem_process_seqs] Processed 723442 reads in 150.033 CPU sec, 4.763 real sec
sorting block 31, #reads = 1077786 mem = 536877631 peak = 1008168960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (112, 285532, 80, 99)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (238, 380, 590)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1294)
[M::mem_pestat] mean and std.dev: (385.36, 242.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1646)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 190, 274)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 554)
[M::mem_pestat] mean and std.dev: (212.04, 100.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 694)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 531, 2185)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6225)
[M::mem_pestat] mean and std.dev: (1008.08, 1183.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8245)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (239, 534, 1254)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3284)
[M::mem_pestat] mean and std.dev: (768.21, 725.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4299)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725142 sequences (100000150 bp) in 2.927 CPU sec, 3.036 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (99, 286930, 66, 72)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 446, 952)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2482)
[M::mem_pestat] mean and std.dev: (515.16, 448.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3247)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 183, 260)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 518)
[M::mem_pestat] mean and std.dev: (202.50, 93.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 647)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (356, 597, 1242)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3014)
[M::mem_pestat] mean and std.dev: (686.85, 486.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3900)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (255, 659, 1329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3477)
[M::mem_pestat] mean and std.dev: (916.64, 893.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4551)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724504 sequences (100000062 bp) in 2.520 CPU sec, 2.522 real sec...
[M::mem_process_seqs] Processed 720126 reads in 206.419 CPU sec, 6.537 real sec
sorting block 32, #reads = 1075891 mem = 536881267 peak = 1008168960
[M::mem_process_seqs] Processed 724616 reads in 147.747 CPU sec, 4.686 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (107, 287831, 62, 91)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 383, 1340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3618)
[M::mem_pestat] mean and std.dev: (759.73, 843.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4757)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 183, 260)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 520)
[M::mem_pestat] mean and std.dev: (202.79, 94.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 650)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 547, 1812)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5016)
[M::mem_pestat] mean and std.dev: (937.63, 985.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6618)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (248, 405, 937)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2315)
[M::mem_pestat] mean and std.dev: (552.64, 447.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3004)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724120 sequences (100000061 bp) in 3.388 CPU sec, 3.519 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (106, 287294, 63, 84)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 309, 850)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2230)
[M::mem_pestat] mean and std.dev: (478.63, 510.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2920)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 184, 261)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 521)
[M::mem_pestat] mean and std.dev: (203.53, 94.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 651)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (260, 556, 827)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1961)
[M::mem_pestat] mean and std.dev: (564.29, 381.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2528)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 449, 816)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2036)
[M::mem_pestat] mean and std.dev: (618.34, 551.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2824)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724470 sequences (100000199 bp) in 2.140 CPU sec, 2.137 real sec...
[M::mem_process_seqs] Processed 725142 reads in 209.778 CPU sec, 6.657 real sec
sorting block 33, #reads = 1076928 mem = 536884525 peak = 1008168960
[M::mem_process_seqs] Processed 724504 reads in 151.335 CPU sec, 4.823 real sec
sorting block 34, #reads = 1078659 mem = 536877216 peak = 1008168960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (127, 287377, 63, 97)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 385, 990)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2528)
[M::mem_pestat] mean and std.dev: (565.35, 514.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3297)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 184, 261)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 521)
[M::mem_pestat] mean and std.dev: (203.24, 94.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 651)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 534, 1278)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3424)
[M::mem_pestat] mean and std.dev: (847.58, 889.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4497)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 348, 734)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1772)
[M::mem_pestat] mean and std.dev: (492.84, 410.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2291)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720624 sequences (100000199 bp) in 3.162 CPU sec, 3.270 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (90, 286630, 68, 95)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (238, 380, 1377)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3655)
[M::mem_pestat] mean and std.dev: (692.30, 708.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4794)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 183, 261)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 521)
[M::mem_pestat] mean and std.dev: (203.38, 94.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 651)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (271, 644, 1150)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2908)
[M::mem_pestat] mean and std.dev: (692.00, 629.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3787)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 388, 725)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1769)
[M::mem_pestat] mean and std.dev: (496.19, 388.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2291)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722534 sequences (100000057 bp) in 2.400 CPU sec, 2.399 real sec...
[M::mem_process_seqs] Processed 724120 reads in 214.754 CPU sec, 6.819 real sec
[M::mem_process_seqs] Processed 724470 reads in 151.674 CPU sec, 4.827 real sec
sorting block 35, #reads = 1079525 mem = 536881403 peak = 1008168960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (96, 285736, 89, 110)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 503, 1676)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4630)
[M::mem_pestat] mean and std.dev: (884.34, 995.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6107)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 189, 270)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 542)
[M::mem_pestat] mean and std.dev: (209.62, 98.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 678)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (236, 511, 1338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3542)
[M::mem_pestat] mean and std.dev: (595.79, 584.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4644)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 416, 944)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2404)
[M::mem_pestat] mean and std.dev: (522.45, 452.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3134)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723424 sequences (100000148 bp) in 3.612 CPU sec, 3.739 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (97, 286237, 69, 106)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (234, 553, 912)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2268)
[M::mem_pestat] mean and std.dev: (589.62, 483.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2946)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 186, 265)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 531)
[M::mem_pestat] mean and std.dev: (206.23, 96.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 664)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 441, 1054)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2752)
[M::mem_pestat] mean and std.dev: (587.80, 523.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3601)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 310, 1058)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2762)
[M::mem_pestat] mean and std.dev: (594.32, 596.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3614)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723274 sequences (100000101 bp) in 2.299 CPU sec, 2.302 real sec...
[M::mem_process_seqs] Processed 720624 reads in 212.465 CPU sec, 6.740 real sec
sorting block 36, #reads = 1077271 mem = 536881336 peak = 1008168960
[M::mem_process_seqs] Processed 722534 reads in 151.980 CPU sec, 4.837 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (116, 286636, 72, 93)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (229, 538, 1082)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2788)
[M::mem_pestat] mean and std.dev: (715.46, 646.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3641)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 185, 262)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 522)
[M::mem_pestat] mean and std.dev: (204.20, 94.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 652)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (345, 681, 1552)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3966)
[M::mem_pestat] mean and std.dev: (832.34, 692.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5173)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (263, 549, 1095)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2759)
[M::mem_pestat] mean and std.dev: (664.63, 529.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3591)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 37, #reads = 1076559 mem = 536878800 peak = 1008168960
[M::process] read 722904 sequences (100000178 bp) in 2.952 CPU sec, 3.059 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (98, 286693, 60, 101)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 309, 1075)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2909)
[M::mem_pestat] mean and std.dev: (612.93, 641.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3826)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 185, 261)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 519)
[M::mem_pestat] mean and std.dev: (203.55, 94.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 648)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 397, 1176)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3084)
[M::mem_pestat] mean and std.dev: (575.62, 511.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4038)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (255, 501, 1157)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2961)
[M::mem_pestat] mean and std.dev: (738.28, 604.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3863)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723014 sequences (100000077 bp) in 2.420 CPU sec, 2.422 real sec...
[M::mem_process_seqs] Processed 723424 reads in 207.849 CPU sec, 6.590 real sec
[M::mem_process_seqs] Processed 723274 reads in 144.302 CPU sec, 4.580 real sec
sorting block 38, #reads = 1077408 mem = 536880162 peak = 1008168960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (104, 286224, 82, 105)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 384, 936)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2406)
[M::mem_pestat] mean and std.dev: (538.60, 429.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3141)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 185, 261)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 519)
[M::mem_pestat] mean and std.dev: (203.60, 93.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 648)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (287, 714, 1282)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3272)
[M::mem_pestat] mean and std.dev: (717.21, 576.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4267)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (342, 694, 1448)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3660)
[M::mem_pestat] mean and std.dev: (987.29, 855.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4766)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723376 sequences (100000161 bp) in 3.398 CPU sec, 3.465 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (114, 286403, 61, 100)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (239, 409, 1170)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3032)
[M::mem_pestat] mean and std.dev: (622.36, 560.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3963)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 185, 260)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 516)
[M::mem_pestat] mean and std.dev: (203.18, 93.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 644)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (86, 363, 1299)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3725)
[M::mem_pestat] mean and std.dev: (564.04, 822.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4938)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 287, 847)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2181)
[M::mem_pestat] mean and std.dev: (505.88, 495.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2848)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723244 sequences (100000197 bp) in 2.430 CPU sec, 2.438 real sec...
[M::mem_process_seqs] Processed 722904 reads in 208.353 CPU sec, 6.588 real sec
[M::mem_process_seqs] Processed 723014 reads in 148.833 CPU sec, 4.715 real sec
sorting block 39, #reads = 1077281 mem = 536887787 peak = 1008168960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (103, 286246, 75, 105)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 430, 805)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1989)
[M::mem_pestat] mean and std.dev: (514.70, 475.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2581)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 184, 259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 515)
[M::mem_pestat] mean and std.dev: (202.55, 93.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 643)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (250, 514, 1417)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3751)
[M::mem_pestat] mean and std.dev: (776.39, 783.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4918)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (236, 507, 980)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2468)
[M::mem_pestat] mean and std.dev: (603.53, 527.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3212)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723092 sequences (100000240 bp) in 3.155 CPU sec, 3.245 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (108, 286716, 59, 100)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (228, 530, 1175)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3069)
[M::mem_pestat] mean and std.dev: (673.71, 562.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4016)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 184, 260)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 516)
[M::mem_pestat] mean and std.dev: (203.02, 93.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 644)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (292, 633, 1109)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2743)
[M::mem_pestat] mean and std.dev: (698.19, 610.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3560)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 459, 1332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3548)
[M::mem_pestat] mean and std.dev: (707.24, 709.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4656)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723662 sequences (100000117 bp) in 2.370 CPU sec, 2.370 real sec...
[M::mem_process_seqs] Processed 723376 reads in 215.266 CPU sec, 6.825 real sec
sorting block 40, #reads = 1076895 mem = 536880181 peak = 1008168960
[M::mem_process_seqs] Processed 723244 reads in 150.924 CPU sec, 4.794 real sec
sorting block 41, #reads = 1077519 mem = 536879219 peak = 1008168960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (76, 286063, 85, 142)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 549, 1015)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2669)
[M::mem_pestat] mean and std.dev: (582.45, 432.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3496)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 184, 260)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 516)
[M::mem_pestat] mean and std.dev: (203.05, 93.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 644)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 554, 1514)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4104)
[M::mem_pestat] mean and std.dev: (924.19, 971.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5399)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 488, 964)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2458)
[M::mem_pestat] mean and std.dev: (620.08, 520.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3205)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723614 sequences (100000059 bp) in 3.241 CPU sec, 3.344 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (91, 286612, 46, 115)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (255, 522, 1056)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2658)
[M::mem_pestat] mean and std.dev: (651.17, 536.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3459)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 184, 259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 515)
[M::mem_pestat] mean and std.dev: (202.74, 93.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 643)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (234, 710, 1445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3867)
[M::mem_pestat] mean and std.dev: (959.50, 898.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5078)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (266, 459, 1265)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3263)
[M::mem_pestat] mean and std.dev: (753.38, 745.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4262)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723670 sequences (100000251 bp) in 2.480 CPU sec, 2.475 real sec...
[M::mem_process_seqs] Processed 723092 reads in 217.126 CPU sec, 7.178 real sec
[M::mem_process_seqs] Processed 723662 reads in 149.201 CPU sec, 4.744 real sec
sorting block 42, #reads = 1078050 mem = 536882249 peak = 1008168960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (106, 286258, 76, 120)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (225, 393, 983)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2499)
[M::mem_pestat] mean and std.dev: (564.45, 532.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3257)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 184, 260)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 518)
[M::mem_pestat] mean and std.dev: (202.83, 93.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 647)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (131, 557, 1569)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4445)
[M::mem_pestat] mean and std.dev: (930.38, 1097.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5883)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (257, 381, 779)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1823)
[M::mem_pestat] mean and std.dev: (528.07, 404.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2345)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720902 sequences (100000300 bp) in 3.320 CPU sec, 3.438 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (93, 285937, 71, 88)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (225, 399, 878)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2184)
[M::mem_pestat] mean and std.dev: (592.84, 509.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2837)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 184, 259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 515)
[M::mem_pestat] mean and std.dev: (202.50, 93.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 643)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (298, 964, 1674)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4426)
[M::mem_pestat] mean and std.dev: (852.81, 679.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5802)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 449, 915)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2331)
[M::mem_pestat] mean and std.dev: (564.57, 499.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3039)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720440 sequences (100000238 bp) in 2.360 CPU sec, 2.359 real sec...
[M::mem_process_seqs] Processed 723614 reads in 213.366 CPU sec, 6.768 real sec
[M::mem_process_seqs] Processed 723670 reads in 151.459 CPU sec, 4.811 real sec
sorting block 43, #reads = 1076356 mem = 536879253 peak = 1008168960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (106, 286306, 75, 94)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 312, 824)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2084)
[M::mem_pestat] mean and std.dev: (429.59, 385.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2714)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 189, 268)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 536)
[M::mem_pestat] mean and std.dev: (208.43, 96.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 670)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 603, 1140)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3084)
[M::mem_pestat] mean and std.dev: (687.70, 588.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4056)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 314, 1022)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2686)
[M::mem_pestat] mean and std.dev: (575.62, 540.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3518)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720952 sequences (100000292 bp) in 3.261 CPU sec, 3.369 real sec...
[M::process] read 722086 sequences (100000171 bp) in 1.990 CPU sec, 1.986 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (106, 286015, 56, 97)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 542, 1211)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3239)
[M::mem_pestat] mean and std.dev: (735.38, 696.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4253)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 190, 270)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 542)
[M::mem_pestat] mean and std.dev: (209.79, 97.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 678)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (135, 433, 1107)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3051)
[M::mem_pestat] mean and std.dev: (628.75, 695.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4023)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 390, 897)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2237)
[M::mem_pestat] mean and std.dev: (519.82, 431.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2907)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 720902 reads in 207.864 CPU sec, 6.600 real sec
sorting block 44, #reads = 1076355 mem = 536887130 peak = 1008168960
[M::mem_process_seqs] Processed 720440 reads in 145.552 CPU sec, 4.639 real sec
sorting block 45, #reads = 1078081 mem = 536880483 peak = 1053429760
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (91, 285609, 66, 113)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (272, 651, 1271)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3269)
[M::mem_pestat] mean and std.dev: (844.39, 719.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4268)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 187, 264)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 526)
[M::mem_pestat] mean and std.dev: (205.91, 95.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 657)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (326, 607, 1606)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4166)
[M::mem_pestat] mean and std.dev: (864.28, 850.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5446)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 378, 1173)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3061)
[M::mem_pestat] mean and std.dev: (628.51, 572.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4005)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 719670 sequences (100000243 bp) in 3.323 CPU sec, 3.410 real sec...
[M::process] read 722108 sequences (100000256 bp) in 2.439 CPU sec, 2.437 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (106, 285817, 74, 97)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 481, 1078)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2830)
[M::mem_pestat] mean and std.dev: (640.20, 544.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3706)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 188, 267)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 533)
[M::mem_pestat] mean and std.dev: (207.91, 96.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 666)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 669, 952)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2498)
[M::mem_pestat] mean and std.dev: (541.03, 472.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3271)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 489, 1239)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3275)
[M::mem_pestat] mean and std.dev: (656.56, 589.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4293)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 722086 reads in 213.234 CPU sec, 6.752 real sec
[M::mem_process_seqs] Processed 720952 reads in 247.904 CPU sec, 7.896 real sec
sorting block 46, #reads = 1077053 mem = 536883448 peak = 1053429760
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (134, 285295, 53, 91)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 326, 791)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1911)
[M::mem_pestat] mean and std.dev: (488.63, 407.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2471)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 190, 272)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 546)
[M::mem_pestat] mean and std.dev: (210.83, 99.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 683)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (265, 697, 1227)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3151)
[M::mem_pestat] mean and std.dev: (732.27, 584.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4113)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (245, 483, 795)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1895)
[M::mem_pestat] mean and std.dev: (550.62, 453.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2445)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724722 sequences (100000164 bp) in 3.174 CPU sec, 3.267 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (111, 286899, 76, 120)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (235, 473, 946)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2368)
[M::mem_pestat] mean and std.dev: (523.81, 431.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3079)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 187, 266)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 532)
[M::mem_pestat] mean and std.dev: (206.97, 96.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 665)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 478, 1559)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4273)
[M::mem_pestat] mean and std.dev: (793.08, 799.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5630)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 399, 1033)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2649)
[M::mem_pestat] mean and std.dev: (712.42, 717.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3583)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725278 sequences (100000152 bp) in 2.310 CPU sec, 2.306 real sec...
[M::mem_process_seqs] Processed 719670 reads in 206.306 CPU sec, 6.533 real sec
[M::mem_process_seqs] Processed 722108 reads in 146.132 CPU sec, 4.639 real sec
sorting block 47, #reads = 1077888 mem = 536878555 peak = 1053429760
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (92, 287379, 56, 79)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 304, 811)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2041)
[M::mem_pestat] mean and std.dev: (461.67, 426.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2656)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 183, 261)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 521)
[M::mem_pestat] mean and std.dev: (203.37, 95.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 651)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (242, 488, 1251)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3269)
[M::mem_pestat] mean and std.dev: (738.68, 655.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4278)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 411, 762)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1876)
[M::mem_pestat] mean and std.dev: (468.21, 402.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2433)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724998 sequences (100000233 bp) in 3.001 CPU sec, 3.108 real sec...
[M::process] read 725632 sequences (100000194 bp) in 2.380 CPU sec, 2.376 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (126, 287317, 70, 113)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (230, 434, 928)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2324)
[M::mem_pestat] mean and std.dev: (601.46, 548.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3022)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 183, 259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 517)
[M::mem_pestat] mean and std.dev: (202.20, 93.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 646)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (336, 729, 1564)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4020)
[M::mem_pestat] mean and std.dev: (985.38, 840.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5248)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (233, 323, 930)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2324)
[M::mem_pestat] mean and std.dev: (532.54, 481.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3021)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 724722 reads in 212.278 CPU sec, 6.734 real sec
sorting block 48, #reads = 1078777 mem = 536881321 peak = 1053429760
[M::mem_process_seqs] Processed 725278 reads in 150.284 CPU sec, 4.785 real sec
sorting block 49, #reads = 1079555 mem = 536878901 peak = 1082748928
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (102, 287698, 74, 117)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 360, 868)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2238)
[M::mem_pestat] mean and std.dev: (398.87, 332.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2923)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 183, 260)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 518)
[M::mem_pestat] mean and std.dev: (202.42, 93.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 647)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 577, 922)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2374)
[M::mem_pestat] mean and std.dev: (634.09, 531.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3100)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (271, 470, 938)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2272)
[M::mem_pestat] mean and std.dev: (548.46, 415.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2939)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724368 sequences (100000055 bp) in 3.208 CPU sec, 3.283 real sec...
[M::process] read 721524 sequences (100000186 bp) in 1.810 CPU sec, 1.804 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (94, 287461, 81, 92)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 298, 769)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1951)
[M::mem_pestat] mean and std.dev: (485.44, 449.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2542)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 182, 258)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 514)
[M::mem_pestat] mean and std.dev: (201.82, 93.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 642)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (261, 628, 1556)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4146)
[M::mem_pestat] mean and std.dev: (901.01, 843.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5441)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 460, 1087)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2831)
[M::mem_pestat] mean and std.dev: (564.70, 480.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3703)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 724998 reads in 205.930 CPU sec, 6.541 real sec
[M::mem_process_seqs] Processed 725632 reads in 145.230 CPU sec, 4.626 real sec
sorting block 50, #reads = 1080648 mem = 536879723 peak = 1082748928
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 286654, 95, 102)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (286, 550, 1274)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3250)
[M::mem_pestat] mean and std.dev: (813.74, 786.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4238)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 184, 262)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 524)
[M::mem_pestat] mean and std.dev: (203.57, 94.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 655)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 571, 1013)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2743)
[M::mem_pestat] mean and std.dev: (642.08, 591.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3608)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 603, 1674)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4612)
[M::mem_pestat] mean and std.dev: (951.32, 973.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6081)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724610 sequences (100000042 bp) in 2.986 CPU sec, 3.070 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (121, 286169, 69, 114)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (265, 461, 1314)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3412)
[M::mem_pestat] mean and std.dev: (831.01, 796.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4461)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 188, 268)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 538)
[M::mem_pestat] mean and std.dev: (208.24, 97.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 673)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 743, 1373)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3757)
[M::mem_pestat] mean and std.dev: (814.86, 758.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4949)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 444, 919)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2305)
[M::mem_pestat] mean and std.dev: (607.51, 501.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2998)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724162 sequences (100000297 bp) in 2.470 CPU sec, 2.471 real sec...
[M::mem_process_seqs] Processed 724368 reads in 209.279 CPU sec, 6.639 real sec
sorting block 51, #reads = 1078543 mem = 536880072 peak = 1082748928
[M::mem_process_seqs] Processed 721524 reads in 157.969 CPU sec, 5.043 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (120, 286824, 59, 123)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 460, 1205)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3207)
[M::mem_pestat] mean and std.dev: (707.03, 629.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4208)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 183, 260)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 518)
[M::mem_pestat] mean and std.dev: (202.51, 94.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 647)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (312, 730, 1363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3465)
[M::mem_pestat] mean and std.dev: (684.23, 474.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4516)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (234, 577, 1435)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3837)
[M::mem_pestat] mean and std.dev: (777.69, 724.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5038)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722586 sequences (100000005 bp) in 3.115 CPU sec, 3.169 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (83, 286285, 70, 133)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 455, 1110)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2916)
[M::mem_pestat] mean and std.dev: (621.40, 556.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3819)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 184, 262)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 524)
[M::mem_pestat] mean and std.dev: (204.14, 95.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 655)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 660, 1470)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4040)
[M::mem_pestat] mean and std.dev: (945.50, 1056.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5325)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 481, 1104)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2886)
[M::mem_pestat] mean and std.dev: (681.58, 661.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3777)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723826 sequences (100000226 bp) in 2.268 CPU sec, 2.268 real sec...
[M::mem_process_seqs] Processed 724610 reads in 212.059 CPU sec, 6.723 real sec
sorting block 52, #reads = 1079041 mem = 536877103 peak = 1082748928
[M::mem_process_seqs] Processed 724162 reads in 151.912 CPU sec, 4.826 real sec
sorting block 53, #reads = 1078927 mem = 536884159 peak = 1085227008
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (116, 286745, 71, 107)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (235, 466, 870)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2140)
[M::mem_pestat] mean and std.dev: (582.88, 452.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2775)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 186, 265)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 531)
[M::mem_pestat] mean and std.dev: (205.93, 96.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 664)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (113, 446, 1224)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3446)
[M::mem_pestat] mean and std.dev: (609.09, 638.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4557)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 435, 940)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2372)
[M::mem_pestat] mean and std.dev: (535.62, 430.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3088)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723394 sequences (100000169 bp) in 3.233 CPU sec, 3.306 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (104, 286630, 57, 131)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (243, 514, 792)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1890)
[M::mem_pestat] mean and std.dev: (557.17, 420.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2439)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 184, 261)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 521)
[M::mem_pestat] mean and std.dev: (203.24, 94.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 651)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (280, 748, 2378)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6574)
[M::mem_pestat] mean and std.dev: (1184.00, 1333.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8672)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 477, 1002)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2602)
[M::mem_pestat] mean and std.dev: (626.50, 526.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3402)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723850 sequences (100000229 bp) in 2.520 CPU sec, 2.520 real sec...
[M::mem_process_seqs] Processed 722586 reads in 215.470 CPU sec, 7.138 real sec
[M::mem_process_seqs] Processed 723826 reads in 147.615 CPU sec, 4.683 real sec
sorting block 54, #reads = 1076986 mem = 536883941 peak = 1085227008
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (96, 286249, 67, 92)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 454, 1307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3507)
[M::mem_pestat] mean and std.dev: (796.20, 761.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4607)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 184, 259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 513)
[M::mem_pestat] mean and std.dev: (202.60, 92.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 640)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (267, 693, 1269)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3273)
[M::mem_pestat] mean and std.dev: (727.67, 666.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4275)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (252, 428, 932)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2292)
[M::mem_pestat] mean and std.dev: (493.04, 370.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2972)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723570 sequences (100000228 bp) in 3.208 CPU sec, 3.290 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (124, 286402, 61, 116)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 317, 791)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1953)
[M::mem_pestat] mean and std.dev: (499.66, 434.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2534)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 184, 259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 515)
[M::mem_pestat] mean and std.dev: (202.52, 93.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 643)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 847, 1930)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5328)
[M::mem_pestat] mean and std.dev: (812.71, 773.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7027)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 370, 747)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1793)
[M::mem_pestat] mean and std.dev: (497.76, 410.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2316)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723282 sequences (100000037 bp) in 2.470 CPU sec, 2.468 real sec...
[M::mem_process_seqs] Processed 723394 reads in 218.689 CPU sec, 6.956 real sec
sorting block 55, #reads = 1076141 mem = 536881422 peak = 1085227008
[M::mem_process_seqs] Processed 723850 reads in 165.612 CPU sec, 5.290 real sec
sorting block 56, #reads = 1076549 mem = 536879401 peak = 1085227008
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (106, 286463, 78, 85)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (229, 450, 802)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1948)
[M::mem_pestat] mean and std.dev: (566.25, 457.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2521)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 184, 259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 515)
[M::mem_pestat] mean and std.dev: (202.58, 93.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 643)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (255, 482, 1050)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2640)
[M::mem_pestat] mean and std.dev: (655.12, 569.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3435)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 423, 1425)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3857)
[M::mem_pestat] mean and std.dev: (727.55, 703.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5073)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723412 sequences (100000280 bp) in 2.955 CPU sec, 2.996 real sec...
[M::process] read 724296 sequences (100000263 bp) in 2.160 CPU sec, 2.158 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (110, 286169, 58, 108)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (242, 426, 1016)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2564)
[M::mem_pestat] mean and std.dev: (564.17, 472.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3338)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 184, 260)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 516)
[M::mem_pestat] mean and std.dev: (202.81, 93.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 644)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (127, 478, 1197)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3337)
[M::mem_pestat] mean and std.dev: (677.31, 717.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4407)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (266, 441, 1096)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2756)
[M::mem_pestat] mean and std.dev: (658.14, 571.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3586)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 723570 reads in 210.319 CPU sec, 6.676 real sec
[M::mem_process_seqs] Processed 723282 reads in 150.105 CPU sec, 4.772 real sec
sorting block 57, #reads = 1075556 mem = 536882099 peak = 1085227008
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (107, 286531, 82, 114)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 335, 573)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1351)
[M::mem_pestat] mean and std.dev: (391.85, 306.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1740)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 184, 260)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 516)
[M::mem_pestat] mean and std.dev: (202.84, 93.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 644)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 413, 1084)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2940)
[M::mem_pestat] mean and std.dev: (603.83, 638.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3868)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (239, 588, 1047)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2663)
[M::mem_pestat] mean and std.dev: (685.25, 645.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3471)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 729384 sequences (100000239 bp) in 3.293 CPU sec, 3.349 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (125, 286359, 78, 85)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 322, 894)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2356)
[M::mem_pestat] mean and std.dev: (463.21, 440.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3087)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 183, 257)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 509)
[M::mem_pestat] mean and std.dev: (201.08, 91.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 635)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (321, 653, 1288)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3222)
[M::mem_pestat] mean and std.dev: (790.21, 708.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4189)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (262, 432, 1254)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3238)
[M::mem_pestat] mean and std.dev: (681.81, 654.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4230)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726308 sequences (100000026 bp) in 2.580 CPU sec, 2.577 real sec...
[M::mem_process_seqs] Processed 723412 reads in 215.712 CPU sec, 6.839 real sec
[M::mem_process_seqs] Processed 724296 reads in 152.755 CPU sec, 4.861 real sec
sorting block 58, #reads = 1076532 mem = 536877614 peak = 1085227008
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (98, 288779, 56, 95)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 370, 833)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2055)
[M::mem_pestat] mean and std.dev: (573.48, 506.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2666)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 176, 247)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 485)
[M::mem_pestat] mean and std.dev: (193.75, 87.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 604)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 529, 1029)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2625)
[M::mem_pestat] mean and std.dev: (598.59, 473.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3423)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 376, 828)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2026)
[M::mem_pestat] mean and std.dev: (509.16, 387.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2625)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 728216 sequences (100000229 bp) in 3.199 CPU sec, 3.253 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 287338, 56, 91)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (262, 388, 772)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1792)
[M::mem_pestat] mean and std.dev: (409.03, 293.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2302)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 180, 255)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 505)
[M::mem_pestat] mean and std.dev: (199.50, 92.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 630)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (135, 449, 911)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2463)
[M::mem_pestat] mean and std.dev: (553.89, 555.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3239)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (274, 350, 662)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1438)
[M::mem_pestat] mean and std.dev: (414.37, 291.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1826)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 728290 sequences (100000124 bp) in 2.872 CPU sec, 2.888 real sec...
[M::mem_process_seqs] Processed 729384 reads in 225.781 CPU sec, 7.156 real sec
sorting block 59, #reads = 1075048 mem = 536880078 peak = 1085227008
[M::mem_process_seqs] Processed 726308 reads in 156.268 CPU sec, 4.952 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (84, 288708, 60, 103)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (254, 587, 956)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2360)
[M::mem_pestat] mean and std.dev: (550.44, 386.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3062)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 178, 251)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 497)
[M::mem_pestat] mean and std.dev: (196.79, 90.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 620)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (304, 796, 1194)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2974)
[M::mem_pestat] mean and std.dev: (809.38, 664.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3864)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (277, 530, 1313)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3385)
[M::mem_pestat] mean and std.dev: (819.68, 705.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4421)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 60, #reads = 1077164 mem = 536884004 peak = 1085227008
[M::process] read 728672 sequences (100000247 bp) in 3.675 CPU sec, 3.773 real sec...
[M::process] read 724232 sequences (100000219 bp) in 2.476 CPU sec, 2.488 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (97, 288298, 59, 86)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (239, 427, 871)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2135)
[M::mem_pestat] mean and std.dev: (501.64, 409.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2767)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 178, 250)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 494)
[M::mem_pestat] mean and std.dev: (195.94, 89.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 616)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (111, 658, 1583)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4527)
[M::mem_pestat] mean and std.dev: (862.33, 1074.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5999)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 484, 1050)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2744)
[M::mem_pestat] mean and std.dev: (637.43, 575.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3591)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 728216 reads in 233.222 CPU sec, 7.406 real sec
[M::mem_process_seqs] Processed 728290 reads in 162.876 CPU sec, 5.189 real sec
sorting block 61, #reads = 1078548 mem = 536878784 peak = 1085227008
[M::process] read 728618 sequences (100000018 bp) in 3.436 CPU sec, 3.530 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (100, 287104, 66, 84)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 404, 790)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1964)
[M::mem_pestat] mean and std.dev: (472.07, 373.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2551)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 184, 261)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 521)
[M::mem_pestat] mean and std.dev: (203.44, 95.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 651)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 513, 898)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2334)
[M::mem_pestat] mean and std.dev: (588.32, 507.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3052)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (252, 476, 1142)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2922)
[M::mem_pestat] mean and std.dev: (631.99, 583.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3812)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 729210 sequences (100000291 bp) in 2.455 CPU sec, 2.454 real sec...
[M::mem_process_seqs] Processed 724232 reads in 133.017 CPU sec, 4.244 real sec
sorting block 62, #reads = 1077276 mem = 536879234 peak = 1085227008
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (91, 289087, 71, 86)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 412, 1014)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2644)
[M::mem_pestat] mean and std.dev: (544.08, 482.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3459)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 178, 250)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 494)
[M::mem_pestat] mean and std.dev: (196.05, 89.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 616)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (326, 821, 1184)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2900)
[M::mem_pestat] mean and std.dev: (781.06, 662.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3758)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 308, 827)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2087)
[M::mem_pestat] mean and std.dev: (429.25, 373.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2717)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (107, 288771, 67, 107)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 341, 508)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1168)
[M::mem_pestat] mean and std.dev: (328.28, 233.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1498)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 178, 250)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 494)
[M::mem_pestat] mean and std.dev: (195.91, 89.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 616)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 666, 1317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3511)
[M::mem_pestat] mean and std.dev: (981.23, 974.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4880)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 483, 943)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2377)
[M::mem_pestat] mean and std.dev: (535.47, 369.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3094)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 728672 reads in 352.971 CPU sec, 11.263 real sec
[M::process] read 728064 sequences (100000122 bp) in 2.738 CPU sec, 2.743 real sec...
[M::mem_process_seqs] Processed 728618 reads in 185.842 CPU sec, 5.943 real sec
sorting block 63, #reads = 1080092 mem = 536877705 peak = 1085227008
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (79, 289040, 56, 81)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 293, 730)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1838)
[M::mem_pestat] mean and std.dev: (444.75, 432.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2392)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 177, 249)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 491)
[M::mem_pestat] mean and std.dev: (195.24, 89.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 612)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (332, 649, 1244)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3068)
[M::mem_pestat] mean and std.dev: (625.40, 491.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3980)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 471, 1075)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2787)
[M::mem_pestat] mean and std.dev: (633.78, 633.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3643)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725048 sequences (100000258 bp) in 3.704 CPU sec, 3.806 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (93, 288452, 80, 93)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 408, 807)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2037)
[M::mem_pestat] mean and std.dev: (476.41, 394.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2652)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 178, 252)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 500)
[M::mem_pestat] mean and std.dev: (197.01, 90.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 624)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (99, 357, 1103)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3111)
[M::mem_pestat] mean and std.dev: (569.51, 617.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4115)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (240, 440, 1183)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3069)
[M::mem_pestat] mean and std.dev: (731.82, 669.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4012)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725178 sequences (100000050 bp) in 2.580 CPU sec, 2.582 real sec...
[M::mem_process_seqs] Processed 729210 reads in 225.303 CPU sec, 7.146 real sec
[M::mem_process_seqs] Processed 728064 reads in 155.645 CPU sec, 4.960 real sec
sorting block 64, #reads = 1077582 mem = 536886191 peak = 1085227008
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (97, 286927, 91, 99)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 305, 994)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2558)
[M::mem_pestat] mean and std.dev: (543.12, 511.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3340)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 182, 259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 515)
[M::mem_pestat] mean and std.dev: (201.78, 93.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 643)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 458, 988)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2570)
[M::mem_pestat] mean and std.dev: (608.11, 558.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3361)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 283, 1177)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3175)
[M::mem_pestat] mean and std.dev: (662.13, 709.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4174)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725088 sequences (100000188 bp) in 3.522 CPU sec, 3.689 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (96, 287265, 89, 90)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 336, 748)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1820)
[M::mem_pestat] mean and std.dev: (473.06, 381.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2356)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 182, 258)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 514)
[M::mem_pestat] mean and std.dev: (201.41, 93.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 642)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 526, 1576)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4368)
[M::mem_pestat] mean and std.dev: (856.14, 1035.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5764)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (290, 776, 1678)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4454)
[M::mem_pestat] mean and std.dev: (922.72, 810.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5842)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723686 sequences (100000296 bp) in 2.482 CPU sec, 2.478 real sec...
[M::mem_process_seqs] Processed 725048 reads in 231.280 CPU sec, 7.379 real sec
sorting block 65, #reads = 1078910 mem = 536878478 peak = 1085227008
[M::mem_process_seqs] Processed 725178 reads in 164.177 CPU sec, 5.241 real sec
sorting block 66, #reads = 1074912 mem = 536881050 peak = 1085227008
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (82, 286877, 83, 91)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (229, 356, 752)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1798)
[M::mem_pestat] mean and std.dev: (442.40, 310.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2321)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 183, 259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 515)
[M::mem_pestat] mean and std.dev: (201.92, 94.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 643)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (116, 394, 1213)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3407)
[M::mem_pestat] mean and std.dev: (577.03, 701.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4504)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (276, 538, 861)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2031)
[M::mem_pestat] mean and std.dev: (533.90, 370.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2616)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723678 sequences (100000036 bp) in 3.498 CPU sec, 3.673 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (103, 286403, 87, 95)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 291, 923)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2413)
[M::mem_pestat] mean and std.dev: (620.72, 666.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3287)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 183, 260)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 516)
[M::mem_pestat] mean and std.dev: (202.69, 93.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 644)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (45, 390, 1087)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3171)
[M::mem_pestat] mean and std.dev: (481.18, 557.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4213)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 392, 1087)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2893)
[M::mem_pestat] mean and std.dev: (614.06, 604.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3796)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722536 sequences (100000176 bp) in 2.570 CPU sec, 2.569 real sec...
[M::mem_process_seqs] Processed 725088 reads in 235.414 CPU sec, 7.499 real sec
[M::mem_process_seqs] Processed 723686 reads in 167.485 CPU sec, 5.342 real sec
sorting block 67, #reads = 1076009 mem = 536881150 peak = 1085227008
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (108, 285995, 63, 111)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 606, 1672)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4586)
[M::mem_pestat] mean and std.dev: (974.20, 975.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6043)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 184, 259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 513)
[M::mem_pestat] mean and std.dev: (202.64, 93.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 640)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (339, 518, 1008)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2346)
[M::mem_pestat] mean and std.dev: (638.75, 501.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3015)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (272, 550, 1199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3053)
[M::mem_pestat] mean and std.dev: (748.17, 632.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3980)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724014 sequences (100000063 bp) in 3.735 CPU sec, 3.935 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (97, 285572, 79, 101)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (238, 492, 1164)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3016)
[M::mem_pestat] mean and std.dev: (659.85, 524.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3942)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 185, 264)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 528)
[M::mem_pestat] mean and std.dev: (205.75, 96.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 660)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (122, 546, 1280)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3596)
[M::mem_pestat] mean and std.dev: (734.48, 771.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4754)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 493, 821)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2025)
[M::mem_pestat] mean and std.dev: (561.33, 445.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2627)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724646 sequences (100000280 bp) in 2.666 CPU sec, 2.673 real sec...
[M::mem_process_seqs] Processed 723678 reads in 240.030 CPU sec, 7.880 real sec
[M::mem_process_seqs] Processed 722536 reads in 166.730 CPU sec, 5.312 real sec
sorting block 68, #reads = 1072855 mem = 536881707 peak = 1085227008
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (84, 286146, 55, 105)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (234, 582, 1754)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4794)
[M::mem_pestat] mean and std.dev: (1010.91, 996.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6314)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 183, 258)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 512)
[M::mem_pestat] mean and std.dev: (202.02, 93.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 639)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (262, 723, 1618)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4330)
[M::mem_pestat] mean and std.dev: (915.53, 873.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5686)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 444, 1259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3355)
[M::mem_pestat] mean and std.dev: (642.70, 681.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4403)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723200 sequences (100000166 bp) in 3.402 CPU sec, 3.560 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (104, 286275, 86, 100)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 481, 1183)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3139)
[M::mem_pestat] mean and std.dev: (660.63, 566.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4117)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 182, 257)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 509)
[M::mem_pestat] mean and std.dev: (201.03, 92.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 635)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (128, 411, 942)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2570)
[M::mem_pestat] mean and std.dev: (548.39, 614.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3384)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 380, 804)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1924)
[M::mem_pestat] mean and std.dev: (480.03, 352.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2484)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724288 sequences (100000258 bp) in 2.524 CPU sec, 2.526 real sec...
[M::mem_process_seqs] Processed 724014 reads in 236.113 CPU sec, 7.516 real sec
sorting block 69, #reads = 1073489 mem = 536880130 peak = 1085227008
[M::mem_process_seqs] Processed 724646 reads in 167.892 CPU sec, 5.361 real sec
sorting block 70, #reads = 1073221 mem = 536886167 peak = 1108500480
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (102, 286391, 83, 91)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 486, 1402)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3860)
[M::mem_pestat] mean and std.dev: (769.73, 771.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5089)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 184, 261)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 519)
[M::mem_pestat] mean and std.dev: (203.64, 94.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 648)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 417, 1598)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4402)
[M::mem_pestat] mean and std.dev: (882.59, 1056.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5804)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 409, 1263)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3377)
[M::mem_pestat] mean and std.dev: (702.06, 694.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4434)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723904 sequences (100000085 bp) in 3.700 CPU sec, 3.836 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (92, 286426, 58, 89)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 533, 917)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2357)
[M::mem_pestat] mean and std.dev: (528.10, 449.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3077)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 183, 258)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 512)
[M::mem_pestat] mean and std.dev: (201.58, 93.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 639)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 463, 1205)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3263)
[M::mem_pestat] mean and std.dev: (720.80, 811.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4292)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (263, 505, 1122)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2840)
[M::mem_pestat] mean and std.dev: (721.02, 608.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3699)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 730198 sequences (100000226 bp) in 2.590 CPU sec, 2.597 real sec...
[M::mem_process_seqs] Processed 723200 reads in 230.457 CPU sec, 7.320 real sec
[M::mem_process_seqs] Processed 724288 reads in 162.991 CPU sec, 5.182 real sec
sorting block 71, #reads = 1074884 mem = 536885161 peak = 1108500480
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (91, 285781, 77, 105)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 433, 1088)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2852)
[M::mem_pestat] mean and std.dev: (626.84, 551.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3734)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 183, 259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 515)
[M::mem_pestat] mean and std.dev: (202.28, 93.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 643)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 532, 1005)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2687)
[M::mem_pestat] mean and std.dev: (684.27, 639.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3528)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (233, 369, 817)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1985)
[M::mem_pestat] mean and std.dev: (553.09, 491.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2569)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 730322 sequences (100000022 bp) in 3.222 CPU sec, 3.317 real sec...
[M::process] read 729538 sequences (100000285 bp) in 2.280 CPU sec, 2.283 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (102, 288366, 77, 90)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 423, 1087)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2899)
[M::mem_pestat] mean and std.dev: (625.03, 574.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3805)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (127, 176, 248)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 490)
[M::mem_pestat] mean and std.dev: (194.38, 88.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 611)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (336, 658, 1427)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3609)
[M::mem_pestat] mean and std.dev: (739.18, 579.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4700)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (256, 613, 997)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2479)
[M::mem_pestat] mean and std.dev: (806.39, 717.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3675)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 723904 reads in 241.679 CPU sec, 7.930 real sec
sorting block 72, #reads = 1074027 mem = 536885160 peak = 1108500480
[M::mem_process_seqs] Processed 730198 reads in 174.137 CPU sec, 5.547 real sec
sorting block 73, #reads = 1072437 mem = 536884545 peak = 1108500480
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (95, 289556, 55, 99)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (242, 624, 1263)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3305)
[M::mem_pestat] mean and std.dev: (848.45, 718.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4326)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (127, 176, 248)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 490)
[M::mem_pestat] mean and std.dev: (194.63, 89.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 611)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (341, 545, 1238)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3032)
[M::mem_pestat] mean and std.dev: (760.73, 604.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3929)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 465, 931)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2337)
[M::mem_pestat] mean and std.dev: (546.19, 447.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3040)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 728590 sequences (100000299 bp) in 3.397 CPU sec, 3.480 real sec...
[M::process] read 728806 sequences (100000173 bp) in 2.610 CPU sec, 2.610 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (101, 288890, 68, 83)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 446, 723)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1775)
[M::mem_pestat] mean and std.dev: (485.27, 366.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2301)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 177, 250)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 494)
[M::mem_pestat] mean and std.dev: (195.86, 89.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 616)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 535, 1237)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3373)
[M::mem_pestat] mean and std.dev: (696.45, 839.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4441)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (238, 475, 773)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1843)
[M::mem_pestat] mean and std.dev: (466.38, 291.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2378)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 730322 reads in 247.713 CPU sec, 7.851 real sec
[M::mem_process_seqs] Processed 729538 reads in 174.605 CPU sec, 5.564 real sec
sorting block 74, #reads = 1070285 mem = 536881793 peak = 1108500480
[M::process] read 726216 sequences (100000019 bp) in 3.130 CPU sec, 3.258 real sec...
[M::process] read 728234 sequences (100000152 bp) in 2.360 CPU sec, 2.368 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (81, 288572, 65, 110)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 373, 955)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2501)
[M::mem_pestat] mean and std.dev: (628.97, 642.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3274)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 178, 251)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 497)
[M::mem_pestat] mean and std.dev: (196.54, 90.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 620)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 650, 1354)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3630)
[M::mem_pestat] mean and std.dev: (723.73, 537.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4768)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (253, 406, 588)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1258)
[M::mem_pestat] mean and std.dev: (404.29, 213.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1593)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 728806 reads in 140.944 CPU sec, 4.533 real sec
sorting block 75, #reads = 1071962 mem = 536880808 peak = 1108500480
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (92, 288830, 57, 123)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 471, 814)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2000)
[M::mem_pestat] mean and std.dev: (518.25, 419.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2593)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 178, 252)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 500)
[M::mem_pestat] mean and std.dev: (197.23, 90.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 624)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (255, 649, 1673)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4509)
[M::mem_pestat] mean and std.dev: (846.84, 890.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5927)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 402, 711)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1693)
[M::mem_pestat] mean and std.dev: (485.04, 362.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2184)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (87, 288307, 87, 98)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (227, 541, 1255)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3311)
[M::mem_pestat] mean and std.dev: (849.66, 822.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4339)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 181, 256)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 508)
[M::mem_pestat] mean and std.dev: (200.24, 92.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 634)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 552, 1244)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3270)
[M::mem_pestat] mean and std.dev: (677.25, 614.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4283)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 450, 956)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2464)
[M::mem_pestat] mean and std.dev: (659.08, 561.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3218)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 729262 sequences (100000012 bp) in 2.820 CPU sec, 2.830 real sec...
[M::mem_process_seqs] Processed 728590 reads in 386.215 CPU sec, 12.343 real sec
[M::mem_process_seqs] Processed 726216 reads in 218.240 CPU sec, 7.072 real sec
sorting block 76, #reads = 1074367 mem = 536877624 peak = 1108500480
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (82, 288806, 61, 89)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (245, 416, 973)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2429)
[M::mem_pestat] mean and std.dev: (564.46, 494.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3157)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 178, 251)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 495)
[M::mem_pestat] mean and std.dev: (196.69, 89.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 617)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (264, 509, 1120)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2832)
[M::mem_pestat] mean and std.dev: (558.09, 494.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3688)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 405, 1278)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3416)
[M::mem_pestat] mean and std.dev: (754.18, 746.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4485)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 728130 sequences (100000088 bp) in 3.715 CPU sec, 3.873 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (86, 289283, 65, 102)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 439, 1215)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3237)
[M::mem_pestat] mean and std.dev: (717.26, 690.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4248)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 177, 249)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 491)
[M::mem_pestat] mean and std.dev: (195.13, 88.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 612)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (225, 566, 1746)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4788)
[M::mem_pestat] mean and std.dev: (971.78, 1123.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6309)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 420, 805)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1961)
[M::mem_pestat] mean and std.dev: (498.94, 417.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2539)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725554 sequences (100000080 bp) in 2.734 CPU sec, 2.743 real sec...
[M::mem_process_seqs] Processed 728234 reads in 243.997 CPU sec, 7.748 real sec
[M::mem_process_seqs] Processed 729262 reads in 172.244 CPU sec, 5.480 real sec
sorting block 77, #reads = 1075812 mem = 536878182 peak = 1108500480
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (87, 288724, 53, 88)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 323, 822)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2134)
[M::mem_pestat] mean and std.dev: (523.25, 531.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2790)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 178, 252)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 500)
[M::mem_pestat] mean and std.dev: (197.53, 91.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 624)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (98, 492, 1910)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5534)
[M::mem_pestat] mean and std.dev: (1013.87, 1216.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7346)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (238, 397, 1227)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3205)
[M::mem_pestat] mean and std.dev: (580.13, 519.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4194)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726038 sequences (100000167 bp) in 3.699 CPU sec, 3.895 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (101, 287765, 85, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 422, 921)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2375)
[M::mem_pestat] mean and std.dev: (512.61, 448.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3102)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 182, 258)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 514)
[M::mem_pestat] mean and std.dev: (201.71, 93.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 642)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (237, 469, 1700)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4626)
[M::mem_pestat] mean and std.dev: (794.56, 774.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6089)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 375, 976)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2552)
[M::mem_pestat] mean and std.dev: (569.44, 539.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3340)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725954 sequences (100000049 bp) in 2.735 CPU sec, 2.745 real sec...
[M::mem_process_seqs] Processed 728130 reads in 246.168 CPU sec, 7.808 real sec
sorting block 78, #reads = 1076091 mem = 536880849 peak = 1108500480
[M::mem_process_seqs] Processed 725554 reads in 169.997 CPU sec, 5.398 real sec
sorting block 79, #reads = 1075479 mem = 536882415 peak = 1114988544
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (79, 288035, 55, 107)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (286, 468, 1015)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2473)
[M::mem_pestat] mean and std.dev: (632.55, 526.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3202)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 181, 257)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 511)
[M::mem_pestat] mean and std.dev: (200.86, 93.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 638)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (254, 597, 1427)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3773)
[M::mem_pestat] mean and std.dev: (812.50, 860.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4946)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (259, 484, 1302)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3388)
[M::mem_pestat] mean and std.dev: (790.08, 748.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4431)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725376 sequences (100000099 bp) in 3.566 CPU sec, 3.687 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (119, 287374, 80, 100)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 328, 625)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1467)
[M::mem_pestat] mean and std.dev: (383.54, 255.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1888)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 181, 257)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 511)
[M::mem_pestat] mean and std.dev: (200.72, 93.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 638)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 519, 1172)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3112)
[M::mem_pestat] mean and std.dev: (667.48, 577.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4082)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 319, 979)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2493)
[M::mem_pestat] mean and std.dev: (563.12, 566.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3250)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724996 sequences (100000270 bp) in 2.601 CPU sec, 2.604 real sec...
[M::mem_process_seqs] Processed 726038 reads in 233.276 CPU sec, 7.405 real sec
[M::mem_process_seqs] Processed 725954 reads in 162.976 CPU sec, 5.188 real sec
sorting block 80, #reads = 1074631 mem = 536880451 peak = 1114988544
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (86, 286766, 64, 118)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 348, 917)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2445)
[M::mem_pestat] mean and std.dev: (507.17, 485.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3209)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 182, 257)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 511)
[M::mem_pestat] mean and std.dev: (201.01, 93.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 638)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 599, 1317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3519)
[M::mem_pestat] mean and std.dev: (620.54, 496.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4620)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 404, 937)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2423)
[M::mem_pestat] mean and std.dev: (555.69, 519.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3166)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722426 sequences (100000167 bp) in 3.582 CPU sec, 3.751 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (101, 286343, 58, 96)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 453, 802)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2012)
[M::mem_pestat] mean and std.dev: (477.64, 387.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2617)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 182, 257)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 509)
[M::mem_pestat] mean and std.dev: (200.97, 92.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 635)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (266, 807, 1514)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4010)
[M::mem_pestat] mean and std.dev: (840.60, 742.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5258)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 427, 835)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2055)
[M::mem_pestat] mean and std.dev: (487.47, 405.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2665)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725218 sequences (100000296 bp) in 2.729 CPU sec, 2.728 real sec...
[M::mem_process_seqs] Processed 725376 reads in 243.126 CPU sec, 8.004 real sec
sorting block 81, #reads = 1074810 mem = 536878421 peak = 1114988544
[M::mem_process_seqs] Processed 724996 reads in 169.113 CPU sec, 5.378 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (118, 285966, 48, 79)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 399, 935)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2425)
[M::mem_pestat] mean and std.dev: (500.08, 411.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3170)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 186, 264)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 528)
[M::mem_pestat] mean and std.dev: (205.89, 96.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 660)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 528, 1268)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3394)
[M::mem_pestat] mean and std.dev: (700.41, 639.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4457)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (279, 436, 897)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2133)
[M::mem_pestat] mean and std.dev: (566.66, 453.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2751)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725064 sequences (100000192 bp) in 3.382 CPU sec, 3.501 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (115, 286755, 62, 98)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 390, 1084)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2868)
[M::mem_pestat] mean and std.dev: (586.89, 545.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3760)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::process] read 725022 sequences (100000192 bp) in 2.723 CPU sec, 2.731 real sec...
[M::mem_pestat] (25, 50, 75) percentile: (131, 182, 257)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 509)
[M::mem_pestat] mean and std.dev: (200.55, 92.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 635)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (127, 310, 855)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2311)
[M::mem_pestat] mean and std.dev: (450.38, 436.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3039)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 307, 766)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1890)
[M::mem_pestat] mean and std.dev: (505.42, 438.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2452)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 722426 reads in 237.320 CPU sec, 7.541 real sec
sorting block 82, #reads = 1074930 mem = 536880251 peak = 1114988544
[M::mem_process_seqs] Processed 725218 reads in 169.513 CPU sec, 5.407 real sec
sorting block 83, #reads = 1073263 mem = 536877631 peak = 1145053184
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (102, 286782, 68, 79)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (239, 385, 769)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1829)
[M::mem_pestat] mean and std.dev: (467.04, 354.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2359)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 182, 257)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 509)
[M::mem_pestat] mean and std.dev: (200.87, 92.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 635)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (146, 481, 1363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3797)
[M::mem_pestat] mean and std.dev: (683.70, 807.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5014)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (241, 374, 704)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1630)
[M::mem_pestat] mean and std.dev: (433.57, 281.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2093)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725928 sequences (100000094 bp) in 3.707 CPU sec, 3.848 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (90, 286194, 67, 94)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 317, 808)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2078)
[M::mem_pestat] mean and std.dev: (453.90, 392.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2713)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 182, 256)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 506)
[M::mem_pestat] mean and std.dev: (200.38, 92.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 631)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 475, 1052)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2800)
[M::mem_pestat] mean and std.dev: (658.07, 623.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3674)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 385, 1082)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2792)
[M::mem_pestat] mean and std.dev: (569.89, 515.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3647)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726756 sequences (100000271 bp) in 2.670 CPU sec, 2.673 real sec...
[M::mem_process_seqs] Processed 725064 reads in 238.584 CPU sec, 7.580 real sec
sorting block 84, #reads = 1072658 mem = 536881369 peak = 1145053184
[M::process] read 728616 sequences (100000119 bp) in 2.875 CPU sec, 2.879 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (115, 287091, 74, 80)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (265, 470, 1144)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2902)
[M::mem_pestat] mean and std.dev: (636.75, 515.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3781)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 181, 255)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 505)
[M::mem_pestat] mean and std.dev: (199.40, 91.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 630)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 513, 882)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2242)
[M::mem_pestat] mean and std.dev: (565.77, 507.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2922)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 370, 828)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2066)
[M::mem_pestat] mean and std.dev: (519.71, 460.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2685)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 725928 reads in 138.722 CPU sec, 4.400 real sec
[M::mem_process_seqs] Processed 725022 reads in 347.032 CPU sec, 11.039 real sec
sorting block 85, #reads = 1074066 mem = 536881173 peak = 1145053184
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (126, 286306, 70, 103)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (258, 376, 1147)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2925)
[M::mem_pestat] mean and std.dev: (650.56, 621.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3814)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 179, 252)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 498)
[M::mem_pestat] mean and std.dev: (197.42, 90.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 621)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 551, 1027)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2659)
[M::mem_pestat] mean and std.dev: (691.52, 648.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3475)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 410, 916)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2300)
[M::mem_pestat] mean and std.dev: (598.58, 524.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2992)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 727474 sequences (100000077 bp) in 3.794 CPU sec, 3.956 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (86, 288694, 46, 99)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (251, 363, 877)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2129)
[M::mem_pestat] mean and std.dev: (416.74, 334.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2755)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 178, 250)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 494)
[M::mem_pestat] mean and std.dev: (196.12, 89.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 616)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 629, 1395)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3761)
[M::mem_pestat] mean and std.dev: (744.50, 713.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4944)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 380, 708)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1704)
[M::mem_pestat] mean and std.dev: (456.50, 346.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2202)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726858 sequences (100000008 bp) in 2.600 CPU sec, 2.600 real sec...
[M::mem_process_seqs] Processed 726756 reads in 299.528 CPU sec, 9.542 real sec
[M::mem_process_seqs] Processed 728616 reads in 179.142 CPU sec, 5.692 real sec
sorting block 86, #reads = 1065517 mem = 536884084 peak = 1145053184
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (114, 288242, 61, 72)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 346, 764)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1954)
[M::mem_pestat] mean and std.dev: (453.33, 402.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2549)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 179, 253)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 501)
[M::mem_pestat] mean and std.dev: (198.20, 91.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 625)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (249, 493, 1278)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3336)
[M::mem_pestat] mean and std.dev: (752.95, 671.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4365)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 368, 680)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1694)
[M::mem_pestat] mean and std.dev: (390.25, 277.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2201)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726508 sequences (100000167 bp) in 3.506 CPU sec, 3.687 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (95, 287989, 77, 75)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 386, 808)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2006)
[M::mem_pestat] mean and std.dev: (507.38, 380.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2605)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 180, 256)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 510)
[M::mem_pestat] mean and std.dev: (199.72, 92.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 637)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 723, 1174)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3206)
[M::mem_pestat] mean and std.dev: (700.11, 607.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4222)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 357, 678)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1594)
[M::mem_pestat] mean and std.dev: (448.90, 332.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2052)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722390 sequences (100000206 bp) in 2.550 CPU sec, 2.554 real sec...
[M::mem_process_seqs] Processed 727474 reads in 226.426 CPU sec, 7.176 real sec
sorting block 87, #reads = 1074929 mem = 536882767 peak = 1145053184
[M::mem_process_seqs] Processed 726858 reads in 159.975 CPU sec, 5.084 real sec
sorting block 88, #reads = 1079071 mem = 536875720 peak = 1145053184
[M::process] read 727770 sequences (100000167 bp) in 3.964 CPU sec, 4.136 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (118, 286402, 58, 80)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 370, 790)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1980)
[M::mem_pestat] mean and std.dev: (465.42, 363.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2575)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 186, 267)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 537)
[M::mem_pestat] mean and std.dev: (207.59, 97.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 672)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (280, 665, 1006)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2458)
[M::mem_pestat] mean and std.dev: (729.64, 584.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3184)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 332, 1088)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2856)
[M::mem_pestat] mean and std.dev: (624.66, 653.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3740)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 727854 sequences (100000281 bp) in 2.560 CPU sec, 2.564 real sec...
[M::mem_process_seqs] Processed 722390 reads in 126.184 CPU sec, 3.968 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 288408, 61, 99)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 362, 781)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1981)
[M::mem_pestat] mean and std.dev: (456.23, 399.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2581)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 180, 256)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 508)
[M::mem_pestat] mean and std.dev: (200.06, 92.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 634)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (144, 370, 984)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2664)
[M::mem_pestat] mean and std.dev: (450.87, 420.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3504)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (240, 395, 892)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2196)
[M::mem_pestat] mean and std.dev: (547.13, 449.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2848)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 288870, 48, 103)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 337, 1050)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2822)
[M::mem_pestat] mean and std.dev: (644.79, 673.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3708)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 179, 253)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 501)
[M::mem_pestat] mean and std.dev: (197.76, 90.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 625)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 507, 1053)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2797)
[M::mem_pestat] mean and std.dev: (540.41, 424.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3669)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 409, 1079)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2795)
[M::mem_pestat] mean and std.dev: (574.06, 521.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3653)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 726508 reads in 354.211 CPU sec, 11.214 real sec
[M::process] read 727746 sequences (100000214 bp) in 3.152 CPU sec, 3.163 real sec...
sorting block 89, #reads = 1077381 mem = 536878861 peak = 1145053184
[M::mem_process_seqs] Processed 727770 reads in 192.044 CPU sec, 6.104 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (90, 288564, 68, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 496, 1598)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4390)
[M::mem_pestat] mean and std.dev: (805.94, 916.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5786)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 179, 252)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 498)
[M::mem_pestat] mean and std.dev: (197.53, 90.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 621)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (226, 632, 1596)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4336)
[M::mem_pestat] mean and std.dev: (832.88, 847.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5706)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 357, 877)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2173)
[M::mem_pestat] mean and std.dev: (545.67, 475.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2821)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 90, #reads = 1079215 mem = 536885467 peak = 1145053184
[M::process] read 727106 sequences (100000107 bp) in 3.412 CPU sec, 3.546 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (77, 288120, 61, 86)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 288, 1160)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3160)
[M::mem_pestat] mean and std.dev: (591.74, 623.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4160)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 179, 252)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 498)
[M::mem_pestat] mean and std.dev: (197.43, 90.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 621)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (120, 717, 1583)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4509)
[M::mem_pestat] mean and std.dev: (889.60, 862.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5972)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (242, 370, 1080)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2756)
[M::mem_pestat] mean and std.dev: (650.36, 633.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3594)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 727388 sequences (100000197 bp) in 2.704 CPU sec, 2.715 real sec...
[M::mem_process_seqs] Processed 727854 reads in 230.860 CPU sec, 7.328 real sec
[M::mem_process_seqs] Processed 727746 reads in 173.666 CPU sec, 5.535 real sec
sorting block 91, #reads = 1077755 mem = 536879492 peak = 1145053184
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (96, 288319, 72, 98)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (228, 455, 1033)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2643)
[M::mem_pestat] mean and std.dev: (596.97, 509.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3448)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 180, 254)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 504)
[M::mem_pestat] mean and std.dev: (198.73, 91.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 629)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (225, 427, 1118)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2904)
[M::mem_pestat] mean and std.dev: (507.62, 495.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3797)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 360, 751)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1915)
[M::mem_pestat] mean and std.dev: (445.53, 382.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2497)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724950 sequences (100000192 bp) in 4.739 CPU sec, 5.153 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (104, 288563, 43, 97)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (227, 590, 1203)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3155)
[M::mem_pestat] mean and std.dev: (661.83, 560.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4131)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 180, 254)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 504)
[M::mem_pestat] mean and std.dev: (198.71, 91.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 629)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (465, 835, 2119)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5427)
[M::mem_pestat] mean and std.dev: (1342.33, 1400.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7081)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (250, 412, 861)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2083)
[M::mem_pestat] mean and std.dev: (532.94, 404.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2694)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 727106 reads in 231.032 CPU sec, 7.353 real sec
[M::mem_process_seqs] Processed 727388 reads in 165.100 CPU sec, 5.222 real sec
[M::process] read 725854 sequences (100000220 bp) in 3.364 CPU sec, 3.520 real sec...
sorting block 92, #reads = 1079471 mem = 536877883 peak = 1145053184
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (93, 287648, 71, 91)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 363, 870)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2186)
[M::mem_pestat] mean and std.dev: (474.61, 382.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2844)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 183, 260)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 518)
[M::mem_pestat] mean and std.dev: (202.85, 94.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 647)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (333, 579, 832)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1830)
[M::mem_pestat] mean and std.dev: (572.96, 359.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2329)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (290, 461, 1427)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3701)
[M::mem_pestat] mean and std.dev: (775.30, 729.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4838)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726564 sequences (100000268 bp) in 3.522 CPU sec, 3.673 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (76, 287689, 61, 85)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 373, 1188)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3208)
[M::mem_pestat] mean and std.dev: (717.43, 674.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4218)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 182, 258)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 514)
[M::mem_pestat] mean and std.dev: (201.27, 93.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 642)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 633, 1663)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4683)
[M::mem_pestat] mean and std.dev: (963.02, 1179.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6193)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (233, 447, 1099)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2831)
[M::mem_pestat] mean and std.dev: (628.58, 539.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3697)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 724950 reads in 228.571 CPU sec, 7.283 real sec
sorting block 93, #reads = 1079377 mem = 536881425 peak = 1145053184
[M::process] read 726188 sequences (100000207 bp) in 2.741 CPU sec, 2.774 real sec...
[M::mem_process_seqs] Processed 725854 reads in 162.267 CPU sec, 5.130 real sec
sorting block 94, #reads = 1076743 mem = 536886011 peak = 1145053184
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (112, 287894, 69, 115)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 386, 902)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2320)
[M::mem_pestat] mean and std.dev: (471.81, 401.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3029)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 180, 255)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 505)
[M::mem_pestat] mean and std.dev: (199.55, 92.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 630)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (272, 480, 945)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2291)
[M::mem_pestat] mean and std.dev: (539.56, 491.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2964)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 299, 844)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2164)
[M::mem_pestat] mean and std.dev: (450.30, 399.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2824)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726468 sequences (100000232 bp) in 2.794 CPU sec, 2.957 real sec...
[M::process] read 726044 sequences (100000017 bp) in 2.362 CPU sec, 2.367 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (99, 287912, 72, 84)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 368, 1245)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3339)
[M::mem_pestat] mean and std.dev: (577.78, 633.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4386)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 181, 256)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 508)
[M::mem_pestat] mean and std.dev: (200.01, 92.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 634)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (108, 545, 1406)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4002)
[M::mem_pestat] mean and std.dev: (762.38, 843.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5300)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (277, 553, 1043)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2575)
[M::mem_pestat] mean and std.dev: (650.18, 484.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3341)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 726564 reads in 225.863 CPU sec, 7.194 real sec
[M::mem_process_seqs] Processed 726188 reads in 158.281 CPU sec, 5.040 real sec
sorting block 95, #reads = 1077366 mem = 536878819 peak = 1145053184
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (94, 287905, 62, 105)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 311, 1111)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2915)
[M::mem_pestat] mean and std.dev: (550.96, 603.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3817)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 181, 256)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 508)
[M::mem_pestat] mean and std.dev: (200.09, 92.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 634)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (375, 850, 1850)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4800)
[M::mem_pestat] mean and std.dev: (1027.70, 905.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6275)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (251, 494, 940)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2318)
[M::mem_pestat] mean and std.dev: (589.54, 475.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3007)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726654 sequences (100000088 bp) in 3.183 CPU sec, 3.327 real sec...
[M::process] read 726584 sequences (100000031 bp) in 2.604 CPU sec, 2.611 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (95, 287467, 67, 93)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 378, 996)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2590)
[M::mem_pestat] mean and std.dev: (507.90, 474.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3387)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 181, 256)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 508)
[M::mem_pestat] mean and std.dev: (200.16, 92.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 634)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (338, 673, 1149)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2771)
[M::mem_pestat] mean and std.dev: (739.48, 652.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3582)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 375, 1240)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3306)
[M::mem_pestat] mean and std.dev: (611.06, 583.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4339)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 726468 reads in 231.486 CPU sec, 7.347 real sec
sorting block 96, #reads = 1078303 mem = 536881779 peak = 1145053184
[M::mem_process_seqs] Processed 726044 reads in 164.471 CPU sec, 5.231 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (89, 287313, 66, 83)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 414, 1056)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2750)
[M::mem_pestat] mean and std.dev: (582.25, 526.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3597)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 180, 254)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 504)
[M::mem_pestat] mean and std.dev: (198.89, 91.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 629)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 402, 1450)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3968)
[M::mem_pestat] mean and std.dev: (695.43, 780.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5227)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (288, 587, 1446)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3762)
[M::mem_pestat] mean and std.dev: (941.15, 911.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4920)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726894 sequences (100000164 bp) in 2.701 CPU sec, 2.804 real sec...
[M::process] read 726968 sequences (100000256 bp) in 2.179 CPU sec, 2.184 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (103, 287462, 64, 115)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 270, 724)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1836)
[M::mem_pestat] mean and std.dev: (389.73, 372.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2392)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 180, 254)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 504)
[M::mem_pestat] mean and std.dev: (198.78, 91.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 629)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (278, 631, 1526)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4022)
[M::mem_pestat] mean and std.dev: (868.43, 844.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5270)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 489, 963)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2461)
[M::mem_pestat] mean and std.dev: (612.68, 533.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3210)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 726654 reads in 238.103 CPU sec, 7.590 real sec
sorting block 97, #reads = 1075959 mem = 536878621 peak = 1145053184
[M::mem_process_seqs] Processed 726584 reads in 169.023 CPU sec, 5.405 real sec
sorting block 98, #reads = 1074652 mem = 536877315 peak = 1170964480
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (86, 287223, 71, 101)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 305, 1011)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2731)
[M::mem_pestat] mean and std.dev: (587.13, 590.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3591)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 179, 254)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 504)
[M::mem_pestat] mean and std.dev: (198.30, 91.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 629)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (286, 725, 1326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3406)
[M::mem_pestat] mean and std.dev: (733.06, 623.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4446)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 373, 857)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2123)
[M::mem_pestat] mean and std.dev: (529.83, 464.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2756)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 728528 sequences (100000077 bp) in 3.154 CPU sec, 3.259 real sec...
[M::process] read 731066 sequences (100000071 bp) in 2.641 CPU sec, 2.642 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (80, 287046, 81, 97)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 495, 1289)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3507)
[M::mem_pestat] mean and std.dev: (655.04, 580.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4616)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 179, 251)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 495)
[M::mem_pestat] mean and std.dev: (196.99, 89.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 617)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (106, 272, 893)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2467)
[M::mem_pestat] mean and std.dev: (462.24, 509.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3254)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (238, 352, 1105)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2839)
[M::mem_pestat] mean and std.dev: (667.68, 630.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3706)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 726894 reads in 240.382 CPU sec, 7.633 real sec
[M::mem_process_seqs] Processed 726968 reads in 171.857 CPU sec, 5.481 real sec
sorting block 99, #reads = 1074706 mem = 536878837 peak = 1170964480
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (104, 287272, 81, 112)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 487, 857)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2165)
[M::mem_pestat] mean and std.dev: (544.25, 412.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2819)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 177, 249)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 491)
[M::mem_pestat] mean and std.dev: (195.17, 88.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 612)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (127, 409, 1152)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3202)
[M::mem_pestat] mean and std.dev: (675.03, 733.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4227)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (234, 390, 775)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1857)
[M::mem_pestat] mean and std.dev: (460.05, 370.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2398)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 730014 sequences (100000206 bp) in 3.492 CPU sec, 3.634 real sec...
[M::process] read 730694 sequences (100000102 bp) in 2.607 CPU sec, 2.609 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 288845, 67, 121)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 395, 1105)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2991)
[M::mem_pestat] mean and std.dev: (558.76, 533.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3934)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (127, 175, 247)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 487)
[M::mem_pestat] mean and std.dev: (194.07, 89.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 607)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (109, 466, 1367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3883)
[M::mem_pestat] mean and std.dev: (690.77, 796.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5141)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 333, 758)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1844)
[M::mem_pestat] mean and std.dev: (425.30, 359.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2387)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 728528 reads in 273.634 CPU sec, 8.706 real sec
sorting block 100, #reads = 1070645 mem = 536878624 peak = 1170964480
[M::mem_process_seqs] Processed 731066 reads in 192.202 CPU sec, 6.113 real sec
sorting block 101, #reads = 1066559 mem = 536880351 peak = 1170964480
[M::process] read 727050 sequences (100000252 bp) in 3.613 CPU sec, 3.726 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (89, 289091, 55, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 370, 938)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2376)
[M::mem_pestat] mean and std.dev: (521.76, 391.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3095)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (127, 176, 249)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 493)
[M::mem_pestat] mean and std.dev: (195.09, 89.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 615)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (119, 615, 1235)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3467)
[M::mem_pestat] mean and std.dev: (676.88, 681.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4583)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 395, 743)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1787)
[M::mem_pestat] mean and std.dev: (461.74, 331.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2309)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 729840 sequences (100000031 bp) in 2.656 CPU sec, 2.656 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (111, 289415, 71, 94)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (234, 398, 1085)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2787)
[M::mem_pestat] mean and std.dev: (657.70, 642.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3638)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (127, 175, 247)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 487)
[M::mem_pestat] mean and std.dev: (193.75, 88.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 607)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (277, 570, 1322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3412)
[M::mem_pestat] mean and std.dev: (586.28, 512.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4457)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (260, 449, 878)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2114)
[M::mem_pestat] mean and std.dev: (612.57, 471.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2732)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 730014 reads in 252.675 CPU sec, 8.013 real sec
[M::mem_process_seqs] Processed 730694 reads in 287.919 CPU sec, 9.168 real sec
sorting block 102, #reads = 1072129 mem = 536882813 peak = 1170964480
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (80, 288006, 76, 110)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 384, 1025)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2723)
[M::mem_pestat] mean and std.dev: (619.23, 632.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3572)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 180, 257)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 513)
[M::mem_pestat] mean and std.dev: (200.41, 93.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 641)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 546, 966)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2564)
[M::mem_pestat] mean and std.dev: (552.72, 499.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3363)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 426, 789)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1963)
[M::mem_pestat] mean and std.dev: (528.82, 444.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2550)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 730994 sequences (100000071 bp) in 3.414 CPU sec, 3.534 real sec...
[M::process] read 731162 sequences (100000077 bp) in 2.660 CPU sec, 2.666 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (100, 288595, 56, 77)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (248, 607, 1293)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3383)
[M::mem_pestat] mean and std.dev: (751.55, 678.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4428)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 176, 248)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 488)
[M::mem_pestat] mean and std.dev: (194.70, 89.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 608)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 466, 1126)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2966)
[M::mem_pestat] mean and std.dev: (576.22, 543.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3886)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (255, 495, 1043)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2619)
[M::mem_pestat] mean and std.dev: (685.76, 580.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3407)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 727050 reads in 244.165 CPU sec, 7.745 real sec
[M::mem_process_seqs] Processed 729840 reads in 172.008 CPU sec, 5.474 real sec
sorting block 103, #reads = 1072629 mem = 536881475 peak = 1170964480
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (98, 289313, 67, 87)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 512, 1368)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3664)
[M::mem_pestat] mean and std.dev: (723.46, 622.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4812)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (127, 175, 246)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 484)
[M::mem_pestat] mean and std.dev: (193.37, 88.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 603)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 276, 546)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1272)
[M::mem_pestat] mean and std.dev: (322.07, 270.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1635)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 336, 778)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1962)
[M::mem_pestat] mean and std.dev: (412.24, 310.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2554)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 729424 sequences (100000189 bp) in 3.608 CPU sec, 3.740 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (88, 289803, 65, 77)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 377, 929)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2403)
[M::mem_pestat] mean and std.dev: (548.56, 552.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3140)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (127, 175, 246)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 484)
[M::mem_pestat] mean and std.dev: (193.18, 87.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 603)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (143, 462, 993)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2693)
[M::mem_pestat] mean and std.dev: (601.48, 605.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3543)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (282, 489, 1098)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2730)
[M::mem_pestat] mean and std.dev: (688.82, 622.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3546)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 728496 sequences (100000139 bp) in 2.607 CPU sec, 2.610 real sec...
[M::mem_process_seqs] Processed 730994 reads in 243.236 CPU sec, 7.731 real sec
sorting block 104, #reads = 1074987 mem = 536879182 peak = 1170964480
[M::mem_process_seqs] Processed 731162 reads in 172.838 CPU sec, 5.495 real sec
sorting block 105, #reads = 1076619 mem = 536884732 peak = 1170964480
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (100, 289106, 51, 113)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 281, 549)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1237)
[M::mem_pestat] mean and std.dev: (365.36, 267.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1581)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 177, 250)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 494)
[M::mem_pestat] mean and std.dev: (195.60, 89.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 616)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (306, 797, 1168)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2892)
[M::mem_pestat] mean and std.dev: (668.52, 421.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3754)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 358, 842)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2132)
[M::mem_pestat] mean and std.dev: (478.61, 413.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2777)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724740 sequences (100000164 bp) in 3.470 CPU sec, 3.592 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (117, 288457, 67, 84)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 314, 1372)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3708)
[M::mem_pestat] mean and std.dev: (673.67, 754.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4876)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 178, 251)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 497)
[M::mem_pestat] mean and std.dev: (196.62, 89.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 620)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 435, 899)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2377)
[M::mem_pestat] mean and std.dev: (559.66, 573.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3116)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (277, 475, 1148)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2890)
[M::mem_pestat] mean and std.dev: (624.29, 544.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3761)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 728168 sequences (100000267 bp) in 2.658 CPU sec, 2.661 real sec...
[M::mem_process_seqs] Processed 729424 reads in 240.210 CPU sec, 7.635 real sec
[M::mem_process_seqs] Processed 728496 reads in 167.219 CPU sec, 5.325 real sec
sorting block 106, #reads = 1076719 mem = 536879844 peak = 1170964480
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (84, 287227, 60, 82)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 345, 1050)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2716)
[M::mem_pestat] mean and std.dev: (610.32, 556.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3549)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 183, 260)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 518)
[M::mem_pestat] mean and std.dev: (202.91, 94.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 647)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 636, 1168)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3144)
[M::mem_pestat] mean and std.dev: (627.15, 696.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4132)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 360, 589)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1391)
[M::mem_pestat] mean and std.dev: (371.26, 246.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1792)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 728016 sequences (100000114 bp) in 3.261 CPU sec, 3.389 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (94, 288403, 56, 86)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 402, 1064)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2804)
[M::mem_pestat] mean and std.dev: (613.73, 543.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3674)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 179, 252)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 500)
[M::mem_pestat] mean and std.dev: (197.53, 90.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 624)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (254, 669, 1401)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3695)
[M::mem_pestat] mean and std.dev: (736.27, 647.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4842)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (253, 440, 770)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1804)
[M::mem_pestat] mean and std.dev: (506.94, 361.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2321)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726680 sequences (100000080 bp) in 2.420 CPU sec, 2.416 real sec...
[M::mem_process_seqs] Processed 724740 reads in 234.283 CPU sec, 7.511 real sec
sorting block 107, #reads = 1075618 mem = 536877497 peak = 1170964480
[M::mem_process_seqs] Processed 728168 reads in 164.936 CPU sec, 5.298 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (98, 288013, 83, 78)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 501, 1059)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2753)
[M::mem_pestat] mean and std.dev: (612.24, 495.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3600)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 179, 252)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 498)
[M::mem_pestat] mean and std.dev: (197.35, 90.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 621)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (228, 464, 1059)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2721)
[M::mem_pestat] mean and std.dev: (628.98, 578.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3552)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 480, 868)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2150)
[M::mem_pestat] mean and std.dev: (509.00, 413.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2791)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 727104 sequences (100000092 bp) in 3.317 CPU sec, 3.451 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (104, 287912, 80, 92)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (226, 540, 1134)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2950)
[M::mem_pestat] mean and std.dev: (692.89, 655.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3858)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 180, 256)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 510)
[M::mem_pestat] mean and std.dev: (199.96, 92.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 637)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 321, 575)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1363)
[M::mem_pestat] mean and std.dev: (396.72, 311.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1757)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 355, 849)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2147)
[M::mem_pestat] mean and std.dev: (495.95, 446.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2796)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726736 sequences (100000167 bp) in 2.370 CPU sec, 2.366 real sec...
[M::mem_process_seqs] Processed 728016 reads in 228.839 CPU sec, 7.276 real sec
sorting block 108, #reads = 1076265 mem = 536878976 peak = 1170964480
[M::mem_process_seqs] Processed 726680 reads in 160.333 CPU sec, 5.102 real sec
sorting block 109, #reads = 1077458 mem = 536880592 peak = 1170964480
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (116, 288127, 66, 108)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 327, 895)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2329)
[M::mem_pestat] mean and std.dev: (433.68, 384.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3046)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 180, 254)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 504)
[M::mem_pestat] mean and std.dev: (198.51, 91.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 629)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (235, 481, 1644)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4462)
[M::mem_pestat] mean and std.dev: (791.44, 863.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5871)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (328, 635, 1169)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2851)
[M::mem_pestat] mean and std.dev: (699.87, 550.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3692)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726320 sequences (100000207 bp) in 3.519 CPU sec, 3.641 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (95, 287791, 85, 119)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (234, 440, 999)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2529)
[M::mem_pestat] mean and std.dev: (512.55, 384.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3294)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 180, 254)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 504)
[M::mem_pestat] mean and std.dev: (199.08, 91.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 629)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 497, 1255)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3457)
[M::mem_pestat] mean and std.dev: (635.62, 642.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4558)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (259, 468, 2340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6502)
[M::mem_pestat] mean and std.dev: (1195.47, 1393.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8583)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726136 sequences (100000196 bp) in 2.630 CPU sec, 2.629 real sec...
[M::mem_process_seqs] Processed 727104 reads in 231.571 CPU sec, 7.348 real sec
[M::mem_process_seqs] Processed 726736 reads in 174.031 CPU sec, 5.528 real sec
sorting block 110, #reads = 1077357 mem = 536876991 peak = 1170964480
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (98, 287156, 61, 82)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (245, 778, 1204)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3122)
[M::mem_pestat] mean and std.dev: (762.02, 609.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4081)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 180, 255)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 505)
[M::mem_pestat] mean and std.dev: (199.00, 91.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 630)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (226, 576, 1175)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3073)
[M::mem_pestat] mean and std.dev: (692.20, 639.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4022)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 421, 1195)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3157)
[M::mem_pestat] mean and std.dev: (733.47, 730.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4138)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726126 sequences (100000128 bp) in 3.346 CPU sec, 3.484 real sec...
[M::process] read 725586 sequences (100000012 bp) in 2.280 CPU sec, 2.281 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (89, 287179, 75, 84)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 337, 934)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2366)
[M::mem_pestat] mean and std.dev: (570.49, 519.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3082)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 181, 255)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 505)
[M::mem_pestat] mean and std.dev: (199.26, 91.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 630)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 389, 834)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2168)
[M::mem_pestat] mean and std.dev: (495.96, 541.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2835)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 512, 1205)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3169)
[M::mem_pestat] mean and std.dev: (695.51, 682.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4151)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 726320 reads in 231.326 CPU sec, 7.340 real sec
sorting block 111, #reads = 1077600 mem = 536877277 peak = 1170964480
[M::mem_process_seqs] Processed 726136 reads in 263.993 CPU sec, 8.412 real sec
sorting block 112, #reads = 1075334 mem = 536878915 peak = 1170964480
[M::process] read 545440 sequences (74968431 bp) in 2.624 CPU sec, 2.700 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (107, 286814, 66, 104)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 521, 1116)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2944)
[M::mem_pestat] mean and std.dev: (710.77, 631.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3858)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 180, 254)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 502)
[M::mem_pestat] mean and std.dev: (198.83, 91.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 626)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (119, 384, 1114)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3104)
[M::mem_pestat] mean and std.dev: (567.50, 633.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4099)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 404, 915)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2363)
[M::mem_pestat] mean and std.dev: (544.98, 490.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3087)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (80, 286786, 72, 104)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 341, 769)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1941)
[M::mem_pestat] mean and std.dev: (477.63, 430.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2527)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 181, 256)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 508)
[M::mem_pestat] mean and std.dev: (200.08, 92.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 634)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 551, 981)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2577)
[M::mem_pestat] mean and std.dev: (506.79, 478.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3375)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 429, 780)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1924)
[M::mem_pestat] mean and std.dev: (523.27, 443.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2496)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (76, 215486, 62, 72)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 494, 986)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2578)
[M::mem_pestat] mean and std.dev: (605.24, 547.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3374)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 179, 251)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 495)
[M::mem_pestat] mean and std.dev: (196.83, 89.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 617)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 630, 1473)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4123)
[M::mem_pestat] mean and std.dev: (692.17, 717.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5448)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 324, 902)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2348)
[M::mem_pestat] mean and std.dev: (479.08, 460.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3071)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 726126 reads in 295.073 CPU sec, 9.779 real sec
[M::mem_process_seqs] Processed 725586 reads in 224.505 CPU sec, 7.263 real sec
[M::mem_process_seqs] Processed 545440 reads in 248.352 CPU sec, 8.061 real sec
sorting block 113, #reads = 1075110 mem = 536878711 peak = 1170964480
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000c06f2
  features: bfebfbff 7ffefbff
  extended: f3bfb7ef fb417ffe
  amd bits: 2c100800 00000121
     brand: INTEL(R) XEON(R) PLATINUM 8559C
threads: 31
algo: bwa-mem
license: sentieon:klib=31
reads: 122333816
overall: 71050444800 mem 22437.254 user 438.168 sys 746.392 real
[main] Version: 0.7.17-r1188
[main] CMD: /opt/conda/share/sentieon-202308.03-3/libexec/bwa mem -K 100000000 -Y -R @RG\tID:A23MHWWLT4.1029_BICJ-T1-TDNA-1_A23MHWWLT4_1.L008\tPU:L008\tSM:1029_BICJ-T1-TDNA-1_A23MHWWLT4_1\tLB:1029_BICJ-T1-TDNA-1_A23MHWWLT4_1\tDS:s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta\tPL:ILLUMINA -t 31 ./BWAIndex/Homo_sapiens_assembly38.fasta.64 1029_BICJ-T1-TDNA-1_A23MHWWLT4_1_R1.fastq.gz 1029_BICJ-T1-TDNA-1_A23MHWWLT4_1_R2.fastq.gz
[main] Real time: 746.430 sec; CPU: 22875.425 sec
sorting block 114, #reads = 991455 mem = 495146357 peak = 1170964480
uniq header count 1
merging 115 blocks
sw version: sentieon-genomics-202308.03
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000c06f2
  features: bfebfbff 7ffefbff
  extended: f3bfb7ef fb417ffe
  amd bits: 2c100800 00000121
     brand: INTEL(R) XEON(R) PLATINUM 8559C
threads: 31 max 192
algo: util-sort
license: sentieon:util=1
output file size: 6769613074
output reads: 123702007
bam_mem_sort: 115 calls 67.448 user 1.102 sys 68.735 real
bam_write: 115 calls 51.256 user 3.480 sys 60.489 real
execute: 1 calls 45.725 user 1.379 sys 798.582 real
merge_files: 1 calls 45.683 user 1.347 sys 51.076 real
parse_chunk: 1839 calls 102.499 user 27.260 sys 132.896 real
read_chunk: 4994 calls 63.359 user 39.794 sys 708.181 real
sort_block: 1 calls 41.771 user 39.275 sys 680.939 real
write_chunk: 3153 calls 45.297 user 1.062 sys 50.081 real
overall: 3841335296 mem 2023.369 user 96.097 sys 798.604 real
ls: cannot access '*.cram': No such file or directory