.command.err - Workdir - DAQ:SENTIEON_BWAMEM (1029_HTI-T1-TDNA-1_A23MHWWLT4_1;L008;0001)

File Info

Filename: .command.err
Full Path: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/07/91e4c13139efabae6cb3523804ef9b/.command.err
Size: 445.6 KB
Task: DAQ:SENTIEON_BWAMEM (1029_HTI-T1-TDNA-1_A23MHWWLT4_1;L008;0001)
Attempt
Content

cmdline: /opt/conda/share/sentieon-202308.03-3/libexec/util sort -r Homo_sapiens_assembly38.fasta -t 31 -o 1029_HTI-T1-TDNA-1_A23MHWWLT4_1.bam --sam2bam -
This software is licensed to bgold@natera.com by Sentieon Inc.
This software is licensed to bgold@natera.com by Sentieon Inc.
version: sentieon-genomics-202308.03
[M::bwa_idx_load_from_disk] read 3171 ALT contigs
[M::main_mem] bwa index loaded in 2090.472 CPU sec, 73.547 real sec
[M::process] read 699638 sequences (100000230 bp) in 0.973 CPU sec, 0.980 real sec...
[M::process] read 695444 sequences (100000260 bp) in 1.538 CPU sec, 1.535 real sec...
[M::process] read 696084 sequences (100000075 bp) in 1.534 CPU sec, 1.554 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 282614, 22, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 697, 1285)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3467)
[M::mem_pestat] mean and std.dev: (868.64, 776.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4558)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 230, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 682)
[M::mem_pestat] mean and std.dev: (254.03, 123.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 857)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 1241, 2867)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8277)
[M::mem_pestat] mean and std.dev: (1506.77, 1690.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10982)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 286, 571)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1347)
[M::mem_pestat] mean and std.dev: (390.83, 289.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1735)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696020 sequences (100000107 bp) in 1.494 CPU sec, 1.548 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 281343, 31, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 402, 717)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1747)
[M::mem_pestat] mean and std.dev: (481.95, 333.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2262)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 244, 353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 731)
[M::mem_pestat] mean and std.dev: (268.28, 130.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 920)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 580, 1510)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4118)
[M::mem_pestat] mean and std.dev: (960.23, 1129.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5480)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 523, 1264)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3342)
[M::mem_pestat] mean and std.dev: (539.60, 431.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4381)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 281324, 32, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (228, 1321, 2194)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6126)
[M::mem_pestat] mean and std.dev: (1331.27, 1453.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8092)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 241, 350)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 724)
[M::mem_pestat] mean and std.dev: (266.21, 130.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 911)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (473, 776, 2083)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5303)
[M::mem_pestat] mean and std.dev: (1096.83, 1068.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6913)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 358, 883)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2307)
[M::mem_pestat] mean and std.dev: (621.14, 587.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3019)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699638 reads in 297.573 CPU sec, 9.630 real sec
[M::mem_process_seqs] Processed 695444 reads in 208.748 CPU sec, 6.843 real sec
[M::mem_process_seqs] Processed 696084 reads in 229.304 CPU sec, 7.504 real sec
sorting block 0, #reads = 1072945 mem = 536881657 peak = 590462976
[M::process] read 698656 sequences (100000036 bp) in 2.189 CPU sec, 2.297 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 281299, 22, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 248, 716)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1770)
[M::mem_pestat] mean and std.dev: (475.32, 402.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2297)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 242, 351)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 727)
[M::mem_pestat] mean and std.dev: (267.08, 131.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 915)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (263, 493, 1490)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3944)
[M::mem_pestat] mean and std.dev: (784.40, 964.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5171)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 531, 872)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2176)
[M::mem_pestat] mean and std.dev: (472.57, 351.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2828)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698374 sequences (100000261 bp) in 1.809 CPU sec, 1.904 real sec...
[M::process] read 698460 sequences (100000121 bp) in 1.575 CPU sec, 1.644 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 282357, 31, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (144, 152, 284)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 564)
[M::mem_pestat] mean and std.dev: (190.55, 75.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 704)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 233, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 695)
[M::mem_pestat] mean and std.dev: (257.70, 126.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 874)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (771, 1113, 1923)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4227)
[M::mem_pestat] mean and std.dev: (1173.89, 872.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5379)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 417, 1002)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2572)
[M::mem_pestat] mean and std.dev: (631.84, 601.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3357)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696020 reads in 193.802 CPU sec, 6.199 real sec
sorting block 1, #reads = 1070994 mem = 536878899 peak = 889307136
[M::mem_process_seqs] Processed 698656 reads in 130.884 CPU sec, 4.210 real sec
sorting block 2, #reads = 1071433 mem = 536881354 peak = 903925760
[M::process] read 698578 sequences (100000277 bp) in 2.009 CPU sec, 2.252 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 282455, 17, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 241, 657)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1641)
[M::mem_pestat] mean and std.dev: (289.19, 265.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2133)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 233, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 696)
[M::mem_pestat] mean and std.dev: (258.54, 126.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 875)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (62, 569, 1505)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4391)
[M::mem_pestat] mean and std.dev: (640.31, 670.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5834)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 383, 481)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 987)
[M::mem_pestat] mean and std.dev: (334.74, 161.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1240)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697658 sequences (100000003 bp) in 1.835 CPU sec, 1.861 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 282250, 38, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 694, 1096)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2894)
[M::mem_pestat] mean and std.dev: (722.74, 683.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3793)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 232, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 695)
[M::mem_pestat] mean and std.dev: (257.50, 126.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 874)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (244, 1153, 2405)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6727)
[M::mem_pestat] mean and std.dev: (1311.51, 1246.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8888)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (237, 364, 887)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2187)
[M::mem_pestat] mean and std.dev: (475.40, 445.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2837)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698374 reads in 202.445 CPU sec, 6.694 real sec
[M::mem_process_seqs] Processed 698460 reads in 135.574 CPU sec, 4.484 real sec
sorting block 3, #reads = 1072916 mem = 536878984 peak = 903925760
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 282266, 38, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 628, 1518)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4180)
[M::mem_pestat] mean and std.dev: (896.74, 788.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5511)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 232, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 692)
[M::mem_pestat] mean and std.dev: (256.73, 125.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 870)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (280, 812, 1268)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3244)
[M::mem_pestat] mean and std.dev: (759.81, 726.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4232)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (303, 409, 1248)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3138)
[M::mem_pestat] mean and std.dev: (615.24, 668.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4083)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694244 sequences (100000027 bp) in 2.190 CPU sec, 2.479 real sec...
[M::process] read 696520 sequences (100000088 bp) in 1.728 CPU sec, 1.738 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 281434, 29, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 244, 427)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 949)
[M::mem_pestat] mean and std.dev: (280.00, 194.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1210)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 235, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 705)
[M::mem_pestat] mean and std.dev: (260.24, 127.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 887)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (235, 616, 3157)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9001)
[M::mem_pestat] mean and std.dev: (1442.45, 1855.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11923)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (308, 561, 1297)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3275)
[M::mem_pestat] mean and std.dev: (657.92, 542.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4264)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698578 reads in 199.194 CPU sec, 6.500 real sec
[M::mem_process_seqs] Processed 697658 reads in 135.495 CPU sec, 4.411 real sec
sorting block 4, #reads = 1072889 mem = 536879964 peak = 903925760
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 281114, 42, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 284, 921)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2403)
[M::mem_pestat] mean and std.dev: (564.10, 543.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3144)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 249, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 748)
[M::mem_pestat] mean and std.dev: (273.29, 134.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 942)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (292, 569, 931)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2209)
[M::mem_pestat] mean and std.dev: (572.71, 506.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2848)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 579, 1499)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4087)
[M::mem_pestat] mean and std.dev: (713.55, 583.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5381)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698070 sequences (100000164 bp) in 2.219 CPU sec, 2.640 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 281763, 23, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 361, 852)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2238)
[M::mem_pestat] mean and std.dev: (563.96, 551.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2931)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 239, 346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 714)
[M::mem_pestat] mean and std.dev: (263.95, 129.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 898)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (525, 664, 1265)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2745)
[M::mem_pestat] mean and std.dev: (826.86, 601.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3485)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 473, 1586)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4382)
[M::mem_pestat] mean and std.dev: (778.33, 808.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5780)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697184 sequences (100000213 bp) in 1.796 CPU sec, 1.805 real sec...
[M::mem_process_seqs] Processed 694244 reads in 198.248 CPU sec, 6.610 real sec
sorting block 5, #reads = 1072395 mem = 536880497 peak = 903925760
[M::mem_process_seqs] Processed 696520 reads in 135.495 CPU sec, 4.424 real sec
sorting block 6, #reads = 1073161 mem = 536881312 peak = 905748480
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 282583, 19, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 334, 699)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1731)
[M::mem_pestat] mean and std.dev: (395.13, 334.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2247)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 234, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 693)
[M::mem_pestat] mean and std.dev: (258.30, 126.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 871)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 211, 1081)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2937)
[M::mem_pestat] mean and std.dev: (506.58, 472.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3865)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 328, 527)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1231)
[M::mem_pestat] mean and std.dev: (305.61, 195.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1583)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697016 sequences (100000259 bp) in 2.370 CPU sec, 2.655 real sec...
[M::process] read 697000 sequences (100000110 bp) in 1.910 CPU sec, 1.921 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 281743, 23, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 312, 727)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1799)
[M::mem_pestat] mean and std.dev: (358.20, 241.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2335)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 236, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 700)
[M::mem_pestat] mean and std.dev: (260.65, 127.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 880)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (417, 696, 3000)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8166)
[M::mem_pestat] mean and std.dev: (1576.30, 1499.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10749)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 385, 786)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1942)
[M::mem_pestat] mean and std.dev: (461.03, 374.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2520)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698070 reads in 204.137 CPU sec, 6.751 real sec
[M::mem_process_seqs] Processed 697184 reads in 135.992 CPU sec, 4.421 real sec
sorting block 7, #reads = 1072971 mem = 536884270 peak = 905748480
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 282428, 19, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 306, 566)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1264)
[M::mem_pestat] mean and std.dev: (336.14, 199.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1613)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 237, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 704)
[M::mem_pestat] mean and std.dev: (261.55, 127.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 885)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 317, 697)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1739)
[M::mem_pestat] mean and std.dev: (373.41, 344.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2260)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (268, 414, 1078)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2698)
[M::mem_pestat] mean and std.dev: (724.64, 683.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3508)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697016 sequences (100000105 bp) in 2.364 CPU sec, 2.722 real sec...
[M::process] read 694998 sequences (100000148 bp) in 1.740 CPU sec, 1.795 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 282199, 27, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 392, 692)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1740)
[M::mem_pestat] mean and std.dev: (374.00, 295.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2264)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 236, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 695)
[M::mem_pestat] mean and std.dev: (259.88, 126.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 873)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (389, 831, 1238)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2936)
[M::mem_pestat] mean and std.dev: (744.29, 501.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3785)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 274, 1013)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2707)
[M::mem_pestat] mean and std.dev: (594.46, 723.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3554)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697016 reads in 198.994 CPU sec, 6.519 real sec
[M::mem_process_seqs] Processed 697000 reads in 133.483 CPU sec, 4.463 real sec
sorting block 8, #reads = 1072980 mem = 536878153 peak = 905748480
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 281702, 41, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 437, 1916)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5312)
[M::mem_pestat] mean and std.dev: (870.89, 820.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7010)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 235, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 695)
[M::mem_pestat] mean and std.dev: (259.69, 126.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 873)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (240, 476, 1879)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5157)
[M::mem_pestat] mean and std.dev: (911.00, 1046.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6796)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 660, 864)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2182)
[M::mem_pestat] mean and std.dev: (660.94, 551.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2869)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694120 sequences (100000194 bp) in 2.514 CPU sec, 2.754 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 280768, 26, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 250, 630)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1480)
[M::mem_pestat] mean and std.dev: (382.39, 335.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1905)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 241, 346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 710)
[M::mem_pestat] mean and std.dev: (265.02, 128.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 892)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (793, 1138, 1197)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2005)
[M::mem_pestat] mean and std.dev: (1000.04, 421.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2685)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 328, 1101)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2873)
[M::mem_pestat] mean and std.dev: (568.97, 501.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3759)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696774 sequences (100000138 bp) in 1.975 CPU sec, 2.073 real sec...
[M::mem_process_seqs] Processed 697016 reads in 203.298 CPU sec, 6.752 real sec
sorting block 9, #reads = 1073209 mem = 536887249 peak = 905748480
[M::mem_process_seqs] Processed 694998 reads in 134.399 CPU sec, 4.380 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 280983, 22, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (259, 410, 1148)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2926)
[M::mem_pestat] mean and std.dev: (648.14, 555.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3815)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 244, 350)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 718)
[M::mem_pestat] mean and std.dev: (267.70, 129.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 902)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (117, 356, 502)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1272)
[M::mem_pestat] mean and std.dev: (347.20, 291.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1657)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (388, 965, 1599)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4021)
[M::mem_pestat] mean and std.dev: (872.50, 674.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5232)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 10, #reads = 1070740 mem = 536883026 peak = 905748480
[M::process] read 696778 sequences (100000148 bp) in 2.465 CPU sec, 2.715 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 281692, 28, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 312, 429)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 911)
[M::mem_pestat] mean and std.dev: (286.09, 136.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1152)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 235, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 686)
[M::mem_pestat] mean and std.dev: (258.26, 124.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 861)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (279, 555, 1939)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5259)
[M::mem_pestat] mean and std.dev: (1030.00, 1023.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6919)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (248, 309, 945)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2339)
[M::mem_pestat] mean and std.dev: (545.92, 423.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3036)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 693982 sequences (100000051 bp) in 1.948 CPU sec, 1.989 real sec...
[M::mem_process_seqs] Processed 694120 reads in 188.662 CPU sec, 6.197 real sec
[M::mem_process_seqs] Processed 696774 reads in 131.604 CPU sec, 4.338 real sec
sorting block 11, #reads = 1072899 mem = 536882147 peak = 905748480
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 282203, 20, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (287, 431, 1707)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4547)
[M::mem_pestat] mean and std.dev: (989.24, 1063.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5967)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 235, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 689)
[M::mem_pestat] mean and std.dev: (258.67, 124.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 865)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (88, 366, 1434)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4126)
[M::mem_pestat] mean and std.dev: (729.89, 887.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5472)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 309, 1512)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4086)
[M::mem_pestat] mean and std.dev: (903.86, 931.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5373)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695566 sequences (100000055 bp) in 2.432 CPU sec, 2.879 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 280260, 28, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 471, 1118)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2960)
[M::mem_pestat] mean and std.dev: (608.94, 647.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3881)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 245, 351)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 721)
[M::mem_pestat] mean and std.dev: (268.57, 129.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 906)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (411, 790, 5341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 15201)
[M::mem_pestat] mean and std.dev: (2999.54, 3563.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 20131)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 379, 975)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2487)
[M::mem_pestat] mean and std.dev: (467.58, 354.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3243)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695424 sequences (100000062 bp) in 2.041 CPU sec, 2.106 real sec...
[M::mem_process_seqs] Processed 696778 reads in 196.138 CPU sec, 6.734 real sec
[M::mem_process_seqs] Processed 693982 reads in 133.448 CPU sec, 4.409 real sec
sorting block 12, #reads = 1072659 mem = 536877731 peak = 905748480
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 281616, 15, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (252, 352, 588)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1260)
[M::mem_pestat] mean and std.dev: (375.22, 224.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1596)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 238, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 697)
[M::mem_pestat] mean and std.dev: (261.46, 125.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 875)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 625, 1175)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3099)
[M::mem_pestat] mean and std.dev: (679.21, 616.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4061)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 324, 567)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1309)
[M::mem_pestat] mean and std.dev: (351.47, 246.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1680)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695702 sequences (100000127 bp) in 2.457 CPU sec, 2.719 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 280954, 30, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 360, 1016)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2664)
[M::mem_pestat] mean and std.dev: (573.12, 552.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3488)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 239, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 697)
[M::mem_pestat] mean and std.dev: (262.02, 125.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 875)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (246, 536, 897)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2199)
[M::mem_pestat] mean and std.dev: (459.33, 403.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2850)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (245, 367, 1308)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3434)
[M::mem_pestat] mean and std.dev: (701.85, 701.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4497)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694994 sequences (100000254 bp) in 1.963 CPU sec, 1.980 real sec...
[M::mem_process_seqs] Processed 695566 reads in 191.053 CPU sec, 6.158 real sec
sorting block 13, #reads = 1071486 mem = 536880557 peak = 905748480
[M::mem_process_seqs] Processed 695424 reads in 130.104 CPU sec, 4.194 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 281115, 32, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 342, 626)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1514)
[M::mem_pestat] mean and std.dev: (460.44, 357.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1958)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 237, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 693)
[M::mem_pestat] mean and std.dev: (260.21, 124.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 870)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (78, 498, 1306)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3762)
[M::mem_pestat] mean and std.dev: (673.53, 703.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4990)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 266, 677)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1721)
[M::mem_pestat] mean and std.dev: (376.78, 339.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2243)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 14, #reads = 1071529 mem = 536891294 peak = 905748480
[M::process] read 693266 sequences (100000054 bp) in 2.763 CPU sec, 3.083 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 280898, 26, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 311, 1472)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4050)
[M::mem_pestat] mean and std.dev: (849.48, 1074.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5339)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 241, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 704)
[M::mem_pestat] mean and std.dev: (263.97, 126.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 884)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (382, 1123, 2409)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6463)
[M::mem_pestat] mean and std.dev: (1271.64, 902.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8490)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 228, 375)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 783)
[M::mem_pestat] mean and std.dev: (244.93, 135.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 987)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694960 sequences (100000113 bp) in 1.922 CPU sec, 1.964 real sec...
[M::mem_process_seqs] Processed 695702 reads in 197.653 CPU sec, 6.605 real sec
[M::mem_process_seqs] Processed 694994 reads in 133.611 CPU sec, 4.294 real sec
sorting block 15, #reads = 1071936 mem = 536891458 peak = 905748480
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 279817, 25, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 317, 697)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1771)
[M::mem_pestat] mean and std.dev: (454.78, 389.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2308)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 247, 351)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 719)
[M::mem_pestat] mean and std.dev: (269.43, 129.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 903)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (345, 814, 2017)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5361)
[M::mem_pestat] mean and std.dev: (875.82, 976.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7033)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 319, 475)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1027)
[M::mem_pestat] mean and std.dev: (259.61, 118.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1303)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695760 sequences (100000115 bp) in 2.583 CPU sec, 2.862 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 280710, 31, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (303, 823, 1420)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3654)
[M::mem_pestat] mean and std.dev: (937.88, 827.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4771)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 240, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 698)
[M::mem_pestat] mean and std.dev: (262.41, 125.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 876)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (453, 845, 1791)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4467)
[M::mem_pestat] mean and std.dev: (1061.29, 911.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5805)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (281, 435, 1054)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2600)
[M::mem_pestat] mean and std.dev: (553.21, 433.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3373)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695680 sequences (100000200 bp) in 1.962 CPU sec, 2.062 real sec...
[M::mem_process_seqs] Processed 693266 reads in 192.470 CPU sec, 6.224 real sec
[M::mem_process_seqs] Processed 694960 reads in 141.502 CPU sec, 4.568 real sec
sorting block 16, #reads = 1070846 mem = 536881766 peak = 905748480
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 281143, 23, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 329, 566)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1312)
[M::mem_pestat] mean and std.dev: (298.56, 152.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1685)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 238, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 691)
[M::mem_pestat] mean and std.dev: (260.43, 124.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 867)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (561, 708, 1027)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1959)
[M::mem_pestat] mean and std.dev: (641.30, 431.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2425)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (329, 758, 1360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3422)
[M::mem_pestat] mean and std.dev: (694.67, 447.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4453)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 693730 sequences (100000066 bp) in 2.546 CPU sec, 2.936 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 281064, 26, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 224, 738)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1894)
[M::mem_pestat] mean and std.dev: (408.13, 410.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2472)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 238, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 690)
[M::mem_pestat] mean and std.dev: (260.02, 124.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 866)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 908, 1844)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5126)
[M::mem_pestat] mean and std.dev: (1132.62, 1111.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6767)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 474, 1016)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2604)
[M::mem_pestat] mean and std.dev: (680.31, 569.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3398)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695634 sequences (100000027 bp) in 2.086 CPU sec, 2.183 real sec...
[M::mem_process_seqs] Processed 695760 reads in 194.423 CPU sec, 6.325 real sec
sorting block 17, #reads = 1073260 mem = 536886027 peak = 905748480
[M::mem_process_seqs] Processed 695680 reads in 140.716 CPU sec, 4.602 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 280868, 26, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 661, 1316)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3578)
[M::mem_pestat] mean and std.dev: (812.13, 739.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4709)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 244, 348)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 712)
[M::mem_pestat] mean and std.dev: (266.77, 127.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 894)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (729, 1348, 2592)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6318)
[M::mem_pestat] mean and std.dev: (1852.88, 1475.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8181)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (263, 496, 1277)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3305)
[M::mem_pestat] mean and std.dev: (740.62, 632.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4319)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695696 sequences (100000263 bp) in 2.656 CPU sec, 3.013 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 280998, 27, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 276, 771)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1965)
[M::mem_pestat] mean and std.dev: (548.12, 541.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2715)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 238, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 696)
[M::mem_pestat] mean and std.dev: (261.51, 126.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 874)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 474, 1312)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3640)
[M::mem_pestat] mean and std.dev: (726.04, 758.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4804)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 360, 957)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2527)
[M::mem_pestat] mean and std.dev: (455.02, 385.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3312)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695306 sequences (100000289 bp) in 2.045 CPU sec, 2.092 real sec...
[M::mem_process_seqs] Processed 693730 reads in 191.286 CPU sec, 6.180 real sec
sorting block 18, #reads = 1071792 mem = 536878133 peak = 905748480
[M::mem_process_seqs] Processed 695634 reads in 131.878 CPU sec, 4.295 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 280967, 27, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 383, 744)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1872)
[M::mem_pestat] mean and std.dev: (426.41, 329.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2436)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 238, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 699)
[M::mem_pestat] mean and std.dev: (261.70, 126.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 878)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (363, 1013, 1427)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3555)
[M::mem_pestat] mean and std.dev: (969.37, 665.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4619)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 373, 1376)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3746)
[M::mem_pestat] mean and std.dev: (752.40, 943.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4931)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 19, #reads = 1071150 mem = 536884660 peak = 905748480
[M::process] read 694632 sequences (100000176 bp) in 2.767 CPU sec, 3.134 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 281509, 32, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (129, 203, 612)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1578)
[M::mem_pestat] mean and std.dev: (272.97, 213.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2061)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 240, 345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 709)
[M::mem_pestat] mean and std.dev: (263.90, 127.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 891)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (443, 1300, 2055)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5279)
[M::mem_pestat] mean and std.dev: (1081.53, 779.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6891)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 380, 977)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2477)
[M::mem_pestat] mean and std.dev: (562.03, 491.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3227)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695696 reads in 197.331 CPU sec, 6.687 real sec
[M::process] read 696008 sequences (100000184 bp) in 2.037 CPU sec, 2.049 real sec...
[M::mem_process_seqs] Processed 695306 reads in 137.534 CPU sec, 4.418 real sec
sorting block 20, #reads = 1072057 mem = 536879828 peak = 905748480
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 280848, 36, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 494, 2042)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5694)
[M::mem_pestat] mean and std.dev: (896.97, 885.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7520)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 242, 348)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 714)
[M::mem_pestat] mean and std.dev: (265.97, 129.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 897)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (469, 1137, 1446)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3400)
[M::mem_pestat] mean and std.dev: (1006.71, 734.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4377)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 375, 513)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1151)
[M::mem_pestat] mean and std.dev: (370.10, 233.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1470)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698238 sequences (100000159 bp) in 2.641 CPU sec, 3.141 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 281091, 27, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 271, 481)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1103)
[M::mem_pestat] mean and std.dev: (282.00, 177.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1414)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 240, 346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 712)
[M::mem_pestat] mean and std.dev: (263.93, 128.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 895)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (279, 551, 1107)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2763)
[M::mem_pestat] mean and std.dev: (731.73, 651.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3591)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (230, 471, 1578)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4274)
[M::mem_pestat] mean and std.dev: (919.64, 991.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5622)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697518 sequences (100000297 bp) in 1.885 CPU sec, 1.887 real sec...
[M::mem_process_seqs] Processed 694632 reads in 194.786 CPU sec, 6.284 real sec
[M::mem_process_seqs] Processed 696008 reads in 135.430 CPU sec, 4.598 real sec
sorting block 21, #reads = 1071946 mem = 536878011 peak = 905748480
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 281911, 25, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (241, 358, 864)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2110)
[M::mem_pestat] mean and std.dev: (554.89, 484.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2733)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 234, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 696)
[M::mem_pestat] mean and std.dev: (258.19, 125.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 875)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (410, 721, 1129)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2567)
[M::mem_pestat] mean and std.dev: (683.57, 517.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3286)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (265, 386, 644)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1402)
[M::mem_pestat] mean and std.dev: (399.18, 248.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1781)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696210 sequences (100000086 bp) in 2.597 CPU sec, 3.108 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 282083, 24, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 522, 2412)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6870)
[M::mem_pestat] mean and std.dev: (1024.63, 1238.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9099)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 236, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 697)
[M::mem_pestat] mean and std.dev: (259.13, 125.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 876)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (283, 773, 2945)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8269)
[M::mem_pestat] mean and std.dev: (1372.23, 1839.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10931)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (265, 422, 1368)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3574)
[M::mem_pestat] mean and std.dev: (687.89, 614.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4677)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698238 reads in 189.985 CPU sec, 6.500 real sec
[M::process] read 697874 sequences (100000261 bp) in 1.792 CPU sec, 1.854 real sec...
sorting block 22, #reads = 1070228 mem = 536879032 peak = 905748480
[M::mem_process_seqs] Processed 697518 reads in 130.140 CPU sec, 4.237 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 281246, 36, 82)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (139, 221, 750)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1972)
[M::mem_pestat] mean and std.dev: (471.97, 553.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2685)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 243, 351)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 727)
[M::mem_pestat] mean and std.dev: (266.80, 130.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 915)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (584, 845, 1418)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3086)
[M::mem_pestat] mean and std.dev: (869.03, 578.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3920)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (299, 426, 744)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1634)
[M::mem_pestat] mean and std.dev: (454.97, 309.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2079)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 23, #reads = 1073459 mem = 536881016 peak = 966766592
[M::process] read 697362 sequences (100000209 bp) in 2.634 CPU sec, 3.076 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 282382, 7, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 529, 1493)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4077)
[M::mem_pestat] mean and std.dev: (797.93, 735.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5369)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 237, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 706)
[M::mem_pestat] mean and std.dev: (260.63, 127.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 888)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (267, 524, 2456)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6834)
[M::mem_pestat] mean and std.dev: (1467.50, 1746.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9023)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 697190 sequences (100000091 bp) in 1.889 CPU sec, 1.925 real sec...
[M::mem_process_seqs] Processed 696210 reads in 189.042 CPU sec, 6.124 real sec
[M::mem_process_seqs] Processed 697874 reads in 132.884 CPU sec, 4.268 real sec
sorting block 24, #reads = 1073297 mem = 536879815 peak = 966766592
[M::process] read 697120 sequences (100000280 bp) in 2.644 CPU sec, 2.911 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 281474, 18, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 314, 773)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1919)
[M::mem_pestat] mean and std.dev: (475.40, 405.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2492)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 238, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 710)
[M::mem_pestat] mean and std.dev: (262.26, 128.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 893)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (602, 876, 1481)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3239)
[M::mem_pestat] mean and std.dev: (1046.12, 826.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4352)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 456, 2327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6573)
[M::mem_pestat] mean and std.dev: (1341.40, 1746.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8696)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697124 sequences (100000110 bp) in 1.849 CPU sec, 2.052 real sec...
[M::mem_process_seqs] Processed 697190 reads in 108.370 CPU sec, 3.462 real sec
sorting block 25, #reads = 1074098 mem = 536879469 peak = 966766592
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 281685, 22, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 252, 529)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1221)
[M::mem_pestat] mean and std.dev: (326.64, 257.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1567)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 237, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 709)
[M::mem_pestat] mean and std.dev: (261.53, 128.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 892)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 620, 880)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2336)
[M::mem_pestat] mean and std.dev: (553.73, 435.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3064)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 297, 434)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 846)
[M::mem_pestat] mean and std.dev: (300.03, 135.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1052)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 281990, 27, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 448, 1050)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2764)
[M::mem_pestat] mean and std.dev: (572.47, 568.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3621)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 239, 345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 713)
[M::mem_pestat] mean and std.dev: (263.12, 128.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 897)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (808, 906, 1565)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3079)
[M::mem_pestat] mean and std.dev: (924.71, 536.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3836)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (231, 632, 2697)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7629)
[M::mem_pestat] mean and std.dev: (1650.48, 2047.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10095)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697362 reads in 294.981 CPU sec, 9.514 real sec
[M::process] read 696708 sequences (100000160 bp) in 2.309 CPU sec, 2.323 real sec...
[M::mem_process_seqs] Processed 697120 reads in 151.034 CPU sec, 4.916 real sec
sorting block 26, #reads = 1074386 mem = 536879057 peak = 966766592
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 281727, 34, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (254, 354, 605)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1307)
[M::mem_pestat] mean and std.dev: (382.30, 241.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1658)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 237, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 703)
[M::mem_pestat] mean and std.dev: (260.42, 126.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 884)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 1726, 8984)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 26652)
[M::mem_pestat] mean and std.dev: (3404.68, 3872.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 35486)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 950, 1826)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5154)
[M::mem_pestat] mean and std.dev: (1126.58, 1171.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6818)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695022 sequences (100000005 bp) in 2.678 CPU sec, 3.011 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 281963, 23, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (292, 419, 1564)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4108)
[M::mem_pestat] mean and std.dev: (683.14, 564.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5380)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 238, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 707)
[M::mem_pestat] mean and std.dev: (261.97, 127.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 889)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (248, 323, 1017)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2555)
[M::mem_pestat] mean and std.dev: (544.57, 484.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3324)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 310, 676)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1644)
[M::mem_pestat] mean and std.dev: (395.14, 290.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2128)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697124 reads in 185.950 CPU sec, 6.108 real sec
[M::process] read 696452 sequences (100000016 bp) in 1.722 CPU sec, 1.757 real sec...
[M::mem_process_seqs] Processed 696708 reads in 135.074 CPU sec, 4.386 real sec
sorting block 27, #reads = 1074281 mem = 536879364 peak = 966766592
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 281106, 29, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (368, 594, 1608)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4088)
[M::mem_pestat] mean and std.dev: (914.05, 771.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5328)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 245, 352)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 726)
[M::mem_pestat] mean and std.dev: (268.59, 130.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 913)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (37, 558, 926)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2704)
[M::mem_pestat] mean and std.dev: (537.00, 457.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3593)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (277, 483, 757)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1717)
[M::mem_pestat] mean and std.dev: (565.64, 396.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2197)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696826 sequences (100000002 bp) in 2.756 CPU sec, 3.142 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 281728, 26, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 454, 906)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2312)
[M::mem_pestat] mean and std.dev: (455.41, 381.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3015)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 239, 345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 711)
[M::mem_pestat] mean and std.dev: (263.16, 128.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 894)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (70, 279, 2387)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7021)
[M::mem_pestat] mean and std.dev: (965.92, 1266.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9338)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (235, 428, 1392)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3706)
[M::mem_pestat] mean and std.dev: (840.03, 1008.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4874)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696866 sequences (100000193 bp) in 1.834 CPU sec, 1.845 real sec...
[M::mem_process_seqs] Processed 695022 reads in 187.602 CPU sec, 6.130 real sec
sorting block 28, #reads = 1074055 mem = 536882144 peak = 966766592
[M::mem_process_seqs] Processed 696452 reads in 129.578 CPU sec, 4.463 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 281770, 28, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 235, 723)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1779)
[M::mem_pestat] mean and std.dev: (409.11, 408.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2307)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 237, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 704)
[M::mem_pestat] mean and std.dev: (261.45, 127.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 885)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (655, 2402, 2597)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6481)
[M::mem_pestat] mean and std.dev: (1776.43, 1312.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8423)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 322, 798)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1998)
[M::mem_pestat] mean and std.dev: (405.74, 335.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2598)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696478 sequences (100000133 bp) in 2.698 CPU sec, 3.089 real sec...
sorting block 29, #reads = 1074578 mem = 536880435 peak = 966766592
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 281624, 18, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 375, 602)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1344)
[M::mem_pestat] mean and std.dev: (417.40, 273.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1715)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 239, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 710)
[M::mem_pestat] mean and std.dev: (262.41, 127.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 893)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 957, 2045)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5805)
[M::mem_pestat] mean and std.dev: (1315.39, 1423.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7685)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 322, 1437)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3933)
[M::mem_pestat] mean and std.dev: (783.46, 893.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5181)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696218 sequences (100000265 bp) in 1.687 CPU sec, 1.792 real sec...
[M::mem_process_seqs] Processed 696826 reads in 192.265 CPU sec, 6.485 real sec
[M::mem_process_seqs] Processed 696866 reads in 128.496 CPU sec, 4.137 real sec
sorting block 30, #reads = 1074786 mem = 536879364 peak = 966766592
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 282278, 22, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 330, 396)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 768)
[M::mem_pestat] mean and std.dev: (294.49, 115.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 954)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 239, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 708)
[M::mem_pestat] mean and std.dev: (262.60, 127.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 890)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (32, 485, 616)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1784)
[M::mem_pestat] mean and std.dev: (334.39, 284.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2368)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 374, 914)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2306)
[M::mem_pestat] mean and std.dev: (586.47, 521.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3002)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695996 sequences (100000233 bp) in 2.678 CPU sec, 3.026 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 282076, 38, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 248, 503)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1175)
[M::mem_pestat] mean and std.dev: (279.62, 166.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1511)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 239, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 708)
[M::mem_pestat] mean and std.dev: (262.47, 127.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 890)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (424, 940, 1321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3115)
[M::mem_pestat] mean and std.dev: (954.47, 778.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4070)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 546, 1351)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3627)
[M::mem_pestat] mean and std.dev: (941.35, 898.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4765)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694124 sequences (100000246 bp) in 1.731 CPU sec, 1.733 real sec...
[M::mem_process_seqs] Processed 696478 reads in 186.094 CPU sec, 6.027 real sec
[M::mem_process_seqs] Processed 696218 reads in 128.024 CPU sec, 4.193 real sec
sorting block 31, #reads = 1074187 mem = 536878849 peak = 966766592
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 281860, 23, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (238, 369, 587)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1285)
[M::mem_pestat] mean and std.dev: (369.85, 222.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1634)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 239, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 708)
[M::mem_pestat] mean and std.dev: (262.89, 127.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 890)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (341, 1343, 2178)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5852)
[M::mem_pestat] mean and std.dev: (1222.45, 1311.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7689)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 357, 465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 999)
[M::mem_pestat] mean and std.dev: (353.07, 200.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1266)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 692996 sequences (100000161 bp) in 2.748 CPU sec, 2.983 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 280533, 26, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 267, 501)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1137)
[M::mem_pestat] mean and std.dev: (301.23, 204.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1455)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 245, 351)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 721)
[M::mem_pestat] mean and std.dev: (268.01, 128.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 906)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (500, 1575, 2430)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6290)
[M::mem_pestat] mean and std.dev: (1467.42, 994.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8220)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (270, 628, 1194)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3042)
[M::mem_pestat] mean and std.dev: (666.31, 537.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3966)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695528 sequences (100000255 bp) in 1.922 CPU sec, 1.936 real sec...
[M::mem_process_seqs] Processed 695996 reads in 190.491 CPU sec, 6.197 real sec
[M::mem_process_seqs] Processed 694124 reads in 128.478 CPU sec, 4.193 real sec
sorting block 32, #reads = 1073730 mem = 536878568 peak = 966766592
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 280270, 20, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 333, 1461)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4043)
[M::mem_pestat] mean and std.dev: (914.30, 1094.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5334)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 250, 357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 733)
[M::mem_pestat] mean and std.dev: (272.44, 131.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 921)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (421, 711, 2945)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7993)
[M::mem_pestat] mean and std.dev: (1606.63, 1883.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10517)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (270, 448, 729)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1647)
[M::mem_pestat] mean and std.dev: (439.22, 261.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2106)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696188 sequences (100000053 bp) in 2.719 CPU sec, 3.029 real sec...
sorting block 33, #reads = 1072360 mem = 536884468 peak = 972505088
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 281013, 22, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 371, 1163)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3077)
[M::mem_pestat] mean and std.dev: (722.71, 731.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4034)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 239, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 700)
[M::mem_pestat] mean and std.dev: (262.02, 126.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 879)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (332, 987, 1084)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2588)
[M::mem_pestat] mean and std.dev: (766.74, 539.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3340)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 362, 1335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3621)
[M::mem_pestat] mean and std.dev: (629.62, 648.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4764)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695842 sequences (100000033 bp) in 1.922 CPU sec, 1.990 real sec...
[M::mem_process_seqs] Processed 692996 reads in 195.766 CPU sec, 6.424 real sec
[M::mem_process_seqs] Processed 695528 reads in 132.565 CPU sec, 4.361 real sec
sorting block 34, #reads = 1072150 mem = 536877624 peak = 972505088
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 281506, 29, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 278, 878)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2326)
[M::mem_pestat] mean and std.dev: (553.92, 601.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3050)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 237, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 693)
[M::mem_pestat] mean and std.dev: (260.09, 125.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 870)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 345, 938)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2352)
[M::mem_pestat] mean and std.dev: (468.33, 424.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3059)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (252, 425, 743)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1725)
[M::mem_pestat] mean and std.dev: (435.85, 296.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2216)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696182 sequences (100000144 bp) in 2.617 CPU sec, 2.951 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 281482, 28, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (245, 429, 906)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2228)
[M::mem_pestat] mean and std.dev: (515.10, 373.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2889)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 240, 345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 709)
[M::mem_pestat] mean and std.dev: (263.65, 128.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 891)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (436, 818, 861)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1711)
[M::mem_pestat] mean and std.dev: (601.87, 301.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2136)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (238, 531, 1543)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4153)
[M::mem_pestat] mean and std.dev: (926.02, 1042.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5458)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696342 sequences (100000132 bp) in 1.729 CPU sec, 1.805 real sec...
[M::mem_process_seqs] Processed 696188 reads in 194.444 CPU sec, 6.382 real sec
[M::mem_process_seqs] Processed 695842 reads in 133.702 CPU sec, 4.335 real sec
sorting block 35, #reads = 1073397 mem = 536881541 peak = 972505088
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 281445, 26, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 258, 560)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1264)
[M::mem_pestat] mean and std.dev: (306.11, 182.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1616)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 237, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 698)
[M::mem_pestat] mean and std.dev: (260.26, 125.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 877)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (284, 551, 1256)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3200)
[M::mem_pestat] mean and std.dev: (758.58, 696.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4172)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (305, 516, 1022)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2456)
[M::mem_pestat] mean and std.dev: (647.09, 531.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3173)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695860 sequences (100000290 bp) in 2.519 CPU sec, 2.851 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 281363, 28, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 279, 843)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2131)
[M::mem_pestat] mean and std.dev: (526.62, 469.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2775)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 237, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 701)
[M::mem_pestat] mean and std.dev: (261.01, 126.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 881)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (291, 602, 1225)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3093)
[M::mem_pestat] mean and std.dev: (796.43, 705.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4027)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (236, 377, 477)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 959)
[M::mem_pestat] mean and std.dev: (371.19, 176.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1200)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696182 reads in 192.279 CPU sec, 6.258 real sec
[M::process] read 694910 sequences (100000141 bp) in 2.183 CPU sec, 2.224 real sec...
sorting block 36, #reads = 1073145 mem = 536881884 peak = 972505088
[M::mem_process_seqs] Processed 696342 reads in 133.340 CPU sec, 4.540 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 281214, 25, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 253, 544)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1276)
[M::mem_pestat] mean and std.dev: (317.05, 225.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1642)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 237, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 690)
[M::mem_pestat] mean and std.dev: (259.69, 124.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 866)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 628, 1036)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2678)
[M::mem_pestat] mean and std.dev: (688.67, 619.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3499)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 290, 523)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1173)
[M::mem_pestat] mean and std.dev: (327.24, 216.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1498)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 693302 sequences (100000256 bp) in 2.561 CPU sec, 3.295 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 281030, 30, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (245, 507, 728)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1694)
[M::mem_pestat] mean and std.dev: (428.85, 244.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2177)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 241, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 704)
[M::mem_pestat] mean and std.dev: (264.13, 126.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 884)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (96, 353, 941)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2631)
[M::mem_pestat] mean and std.dev: (655.10, 756.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3680)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 303, 685)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1667)
[M::mem_pestat] mean and std.dev: (429.74, 366.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2158)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695854 sequences (100000100 bp) in 1.788 CPU sec, 1.837 real sec...
[M::mem_process_seqs] Processed 695860 reads in 194.062 CPU sec, 6.584 real sec
sorting block 37, #reads = 1073146 mem = 536877697 peak = 972505088
[M::mem_process_seqs] Processed 694910 reads in 130.454 CPU sec, 4.217 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 280234, 15, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 259, 836)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2168)
[M::mem_pestat] mean and std.dev: (528.04, 510.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2834)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 247, 352)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 722)
[M::mem_pestat] mean and std.dev: (269.20, 129.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 907)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (431, 601, 876)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1766)
[M::mem_pestat] mean and std.dev: (541.25, 196.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2211)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (230, 316, 574)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1262)
[M::mem_pestat] mean and std.dev: (368.52, 228.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1606)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 38, #reads = 1072614 mem = 536878816 peak = 981512192
[M::process] read 696084 sequences (100000299 bp) in 2.588 CPU sec, 3.110 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 280803, 34, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 490, 1002)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2688)
[M::mem_pestat] mean and std.dev: (622.54, 609.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3531)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 238, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 693)
[M::mem_pestat] mean and std.dev: (260.40, 124.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 870)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (392, 690, 891)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1889)
[M::mem_pestat] mean and std.dev: (516.39, 310.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2388)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 406, 558)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1236)
[M::mem_pestat] mean and std.dev: (403.94, 242.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1575)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695536 sequences (100000261 bp) in 2.074 CPU sec, 2.175 real sec...
[M::mem_process_seqs] Processed 693302 reads in 196.859 CPU sec, 6.536 real sec
[M::mem_process_seqs] Processed 695854 reads in 134.664 CPU sec, 4.370 real sec
sorting block 39, #reads = 1072337 mem = 536878427 peak = 981512192
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 281529, 27, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (140, 280, 493)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1199)
[M::mem_pestat] mean and std.dev: (269.65, 159.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1552)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 236, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 693)
[M::mem_pestat] mean and std.dev: (259.98, 125.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 870)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (556, 946, 1888)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4552)
[M::mem_pestat] mean and std.dev: (1303.59, 1044.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5884)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (254, 406, 2033)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5591)
[M::mem_pestat] mean and std.dev: (1034.02, 964.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7370)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695556 sequences (100000292 bp) in 2.483 CPU sec, 2.807 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 281572, 19, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 298, 438)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 930)
[M::mem_pestat] mean and std.dev: (279.36, 124.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1176)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 239, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 694)
[M::mem_pestat] mean and std.dev: (261.03, 125.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 871)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (493, 851, 2587)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6775)
[M::mem_pestat] mean and std.dev: (1157.94, 1095.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8869)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 264, 629)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1449)
[M::mem_pestat] mean and std.dev: (405.13, 299.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1859)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696084 reads in 190.543 CPU sec, 6.236 real sec
[M::process] read 695712 sequences (100000038 bp) in 1.876 CPU sec, 1.902 real sec...
[M::mem_process_seqs] Processed 695536 reads in 137.054 CPU sec, 4.494 real sec
sorting block 40, #reads = 1072822 mem = 536878509 peak = 981512192
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 281070, 33, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 449, 1604)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4402)
[M::mem_pestat] mean and std.dev: (926.96, 972.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5801)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 238, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 694)
[M::mem_pestat] mean and std.dev: (260.59, 124.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 871)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (251, 539, 1765)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4793)
[M::mem_pestat] mean and std.dev: (1116.59, 1170.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6307)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 609, 1009)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2639)
[M::mem_pestat] mean and std.dev: (726.78, 686.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3472)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696438 sequences (100000223 bp) in 2.481 CPU sec, 3.034 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 281192, 22, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 284, 588)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1378)
[M::mem_pestat] mean and std.dev: (347.31, 265.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1773)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 238, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 694)
[M::mem_pestat] mean and std.dev: (261.15, 125.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 871)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (96, 815, 1184)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3360)
[M::mem_pestat] mean and std.dev: (745.14, 633.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4448)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 305, 1144)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3074)
[M::mem_pestat] mean and std.dev: (510.97, 503.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4039)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696168 sequences (100000150 bp) in 1.970 CPU sec, 1.981 real sec...
[M::mem_process_seqs] Processed 695556 reads in 187.254 CPU sec, 6.093 real sec
sorting block 41, #reads = 1073028 mem = 536880415 peak = 981512192
[M::mem_process_seqs] Processed 695712 reads in 130.795 CPU sec, 4.216 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 281976, 20, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (249, 660, 1329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3489)
[M::mem_pestat] mean and std.dev: (841.22, 743.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4569)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 236, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 701)
[M::mem_pestat] mean and std.dev: (260.82, 126.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 881)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (282, 466, 1498)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3930)
[M::mem_pestat] mean and std.dev: (805.65, 749.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5146)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (252, 362, 782)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1842)
[M::mem_pestat] mean and std.dev: (462.44, 382.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2372)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 42, #reads = 1072514 mem = 536879169 peak = 1000976384
[M::process] read 695972 sequences (100000070 bp) in 2.557 CPU sec, 3.278 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 281183, 19, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (294, 374, 990)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2382)
[M::mem_pestat] mean and std.dev: (506.43, 429.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3078)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 237, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 699)
[M::mem_pestat] mean and std.dev: (261.29, 127.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 878)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 503, 2196)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6230)
[M::mem_pestat] mean and std.dev: (878.11, 871.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8247)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 544, 2417)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6911)
[M::mem_pestat] mean and std.dev: (1243.62, 1354.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9158)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699010 sequences (100000176 bp) in 1.838 CPU sec, 1.892 real sec...
[M::mem_process_seqs] Processed 696438 reads in 198.747 CPU sec, 6.502 real sec
[M::mem_process_seqs] Processed 696168 reads in 135.507 CPU sec, 4.403 real sec
sorting block 43, #reads = 1072411 mem = 536878379 peak = 1000976384
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 280830, 32, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 305, 1202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3236)
[M::mem_pestat] mean and std.dev: (487.56, 627.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4253)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 237, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 699)
[M::mem_pestat] mean and std.dev: (261.33, 127.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 878)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (253, 709, 1780)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4834)
[M::mem_pestat] mean and std.dev: (971.00, 1001.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6361)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 387, 772)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1932)
[M::mem_pestat] mean and std.dev: (496.14, 454.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2512)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698640 sequences (100000167 bp) in 2.447 CPU sec, 2.905 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 282157, 24, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 271, 982)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2502)
[M::mem_pestat] mean and std.dev: (360.07, 331.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3262)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 232, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 686)
[M::mem_pestat] mean and std.dev: (255.06, 123.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 862)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (94, 436, 955)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2677)
[M::mem_pestat] mean and std.dev: (513.96, 513.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3538)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 236, 647)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1619)
[M::mem_pestat] mean and std.dev: (322.57, 252.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2105)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698582 sequences (100000271 bp) in 2.176 CPU sec, 2.269 real sec...
[M::mem_process_seqs] Processed 695972 reads in 204.792 CPU sec, 6.766 real sec
[M::mem_process_seqs] Processed 699010 reads in 138.783 CPU sec, 4.552 real sec
sorting block 44, #reads = 1070662 mem = 536879228 peak = 1000976384
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 282583, 18, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (237, 408, 1100)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2826)
[M::mem_pestat] mean and std.dev: (689.61, 581.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3689)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 234, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 692)
[M::mem_pestat] mean and std.dev: (256.89, 123.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 870)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 699, 1332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3576)
[M::mem_pestat] mean and std.dev: (833.47, 843.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4698)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 389, 1084)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2822)
[M::mem_pestat] mean and std.dev: (709.36, 646.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3691)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698438 sequences (100000234 bp) in 2.527 CPU sec, 3.153 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 282204, 14, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 304, 2128)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6060)
[M::mem_pestat] mean and std.dev: (1242.72, 1646.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8026)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 234, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 693)
[M::mem_pestat] mean and std.dev: (256.98, 123.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 871)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (122, 625, 4572)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13472)
[M::mem_pestat] mean and std.dev: (1793.93, 2497.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17922)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 273, 427)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 897)
[M::mem_pestat] mean and std.dev: (247.10, 97.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1132)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697616 sequences (100000097 bp) in 1.762 CPU sec, 1.826 real sec...
[M::mem_process_seqs] Processed 698640 reads in 202.288 CPU sec, 6.638 real sec
sorting block 45, #reads = 1070940 mem = 536880017 peak = 1000976384
[M::mem_process_seqs] Processed 698582 reads in 135.525 CPU sec, 4.418 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 282363, 28, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 375, 829)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2065)
[M::mem_pestat] mean and std.dev: (400.16, 330.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2683)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 235, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 693)
[M::mem_pestat] mean and std.dev: (257.94, 124.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 871)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 463, 1031)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2663)
[M::mem_pestat] mean and std.dev: (605.18, 429.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3479)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 300, 640)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1540)
[M::mem_pestat] mean and std.dev: (366.54, 280.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1990)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696774 sequences (100000272 bp) in 2.629 CPU sec, 2.979 real sec...
sorting block 46, #reads = 1073013 mem = 536880654 peak = 1000976384
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 281944, 26, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (135, 217, 928)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2514)
[M::mem_pestat] mean and std.dev: (408.55, 486.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3307)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 236, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 697)
[M::mem_pestat] mean and std.dev: (258.87, 124.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 876)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (126, 714, 1277)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3579)
[M::mem_pestat] mean and std.dev: (928.12, 884.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4730)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 361, 1280)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3408)
[M::mem_pestat] mean and std.dev: (755.88, 804.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4472)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698438 reads in 193.557 CPU sec, 6.385 real sec
[M::process] read 696876 sequences (100000195 bp) in 2.037 CPU sec, 2.113 real sec...
[M::mem_process_seqs] Processed 697616 reads in 133.435 CPU sec, 4.621 real sec
sorting block 47, #reads = 1072536 mem = 536879392 peak = 1000976384
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 281821, 29, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (261, 548, 1325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3453)
[M::mem_pestat] mean and std.dev: (729.20, 533.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4517)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 238, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 707)
[M::mem_pestat] mean and std.dev: (261.60, 126.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 889)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (464, 910, 2530)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6662)
[M::mem_pestat] mean and std.dev: (1332.97, 1175.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8728)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 326, 592)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1362)
[M::mem_pestat] mean and std.dev: (355.41, 204.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1747)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695000 sequences (100000169 bp) in 2.722 CPU sec, 3.172 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 281387, 20, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (411, 605, 1487)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3639)
[M::mem_pestat] mean and std.dev: (779.03, 707.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4715)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 238, 345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 713)
[M::mem_pestat] mean and std.dev: (262.72, 128.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 897)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 442, 614)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1538)
[M::mem_pestat] mean and std.dev: (346.61, 212.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2000)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (294, 435, 1011)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2445)
[M::mem_pestat] mean and std.dev: (677.09, 648.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3271)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694434 sequences (100000065 bp) in 1.706 CPU sec, 1.712 real sec...
[M::mem_process_seqs] Processed 696774 reads in 196.913 CPU sec, 6.588 real sec
[M::mem_process_seqs] Processed 696876 reads in 132.229 CPU sec, 4.270 real sec
sorting block 48, #reads = 1071890 mem = 536889627 peak = 1000976384
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 281017, 21, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 523, 1081)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2815)
[M::mem_pestat] mean and std.dev: (710.58, 635.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3682)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 248, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 744)
[M::mem_pestat] mean and std.dev: (271.21, 132.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 937)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (141, 825, 963)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2607)
[M::mem_pestat] mean and std.dev: (650.84, 516.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3429)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 256, 500)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1130)
[M::mem_pestat] mean and std.dev: (299.69, 180.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1445)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697342 sequences (100000271 bp) in 2.767 CPU sec, 3.156 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 281096, 31, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (144, 218, 402)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 918)
[M::mem_pestat] mean and std.dev: (210.69, 96.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1176)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 247, 355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 733)
[M::mem_pestat] mean and std.dev: (270.14, 130.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 922)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (459, 1087, 1426)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3360)
[M::mem_pestat] mean and std.dev: (861.89, 671.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4327)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 266, 572)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1380)
[M::mem_pestat] mean and std.dev: (363.31, 285.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1784)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697440 sequences (100000017 bp) in 1.990 CPU sec, 1.999 real sec...
[M::mem_process_seqs] Processed 695000 reads in 190.231 CPU sec, 6.179 real sec
[M::mem_process_seqs] Processed 694434 reads in 130.282 CPU sec, 4.243 real sec
sorting block 49, #reads = 1073518 mem = 536883183 peak = 1000976384
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 282078, 22, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 223, 1018)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2726)
[M::mem_pestat] mean and std.dev: (405.22, 413.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3580)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 236, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 697)
[M::mem_pestat] mean and std.dev: (259.26, 124.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 876)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (462, 1678, 2044)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5208)
[M::mem_pestat] mean and std.dev: (1427.67, 1186.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6790)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (234, 448, 887)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2193)
[M::mem_pestat] mean and std.dev: (583.02, 532.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2846)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696986 sequences (100000137 bp) in 2.567 CPU sec, 2.850 real sec...
sorting block 50, #reads = 1072248 mem = 536878954 peak = 1000976384
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 282382, 16, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (145, 206, 815)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2155)
[M::mem_pestat] mean and std.dev: (413.15, 376.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2825)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 236, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 700)
[M::mem_pestat] mean and std.dev: (259.71, 125.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 880)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 325, 1083)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2947)
[M::mem_pestat] mean and std.dev: (514.87, 471.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3879)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (241, 417, 866)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2116)
[M::mem_pestat] mean and std.dev: (480.26, 393.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2741)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696816 sequences (100000215 bp) in 1.744 CPU sec, 1.782 real sec...
[M::mem_process_seqs] Processed 697342 reads in 194.622 CPU sec, 6.421 real sec
[M::mem_process_seqs] Processed 697440 reads in 131.448 CPU sec, 4.312 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 281722, 38, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 378, 1675)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4647)
[M::mem_pestat] mean and std.dev: (1009.45, 1206.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6133)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 237, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 704)
[M::mem_pestat] mean and std.dev: (261.42, 127.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 885)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (140, 388, 929)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2507)
[M::mem_pestat] mean and std.dev: (627.95, 621.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3296)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 335, 621)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1523)
[M::mem_pestat] mean and std.dev: (300.86, 167.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1974)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 51, #reads = 1074593 mem = 536877970 peak = 1000976384
[M::process] read 696806 sequences (100000077 bp) in 2.567 CPU sec, 2.775 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 281732, 30, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 230, 697)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1759)
[M::mem_pestat] mean and std.dev: (475.81, 456.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2301)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 237, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 704)
[M::mem_pestat] mean and std.dev: (261.26, 127.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 885)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (420, 1648, 5017)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 14211)
[M::mem_pestat] mean and std.dev: (3029.43, 3374.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 18808)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 506, 2055)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5723)
[M::mem_pestat] mean and std.dev: (954.90, 919.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7557)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696514 sequences (100000042 bp) in 2.039 CPU sec, 2.054 real sec...
[M::mem_process_seqs] Processed 696986 reads in 189.709 CPU sec, 6.189 real sec
[M::mem_process_seqs] Processed 696816 reads in 132.171 CPU sec, 4.376 real sec
sorting block 52, #reads = 1073818 mem = 536878737 peak = 1000976384
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 282177, 30, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (347, 648, 1716)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4454)
[M::mem_pestat] mean and std.dev: (735.69, 692.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5823)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 238, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 701)
[M::mem_pestat] mean and std.dev: (260.93, 126.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 881)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (45, 474, 765)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2205)
[M::mem_pestat] mean and std.dev: (354.16, 327.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2925)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 413, 641)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1477)
[M::mem_pestat] mean and std.dev: (406.53, 248.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1895)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696546 sequences (100000283 bp) in 2.550 CPU sec, 2.795 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 281199, 21, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (256, 485, 1393)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3667)
[M::mem_pestat] mean and std.dev: (850.24, 928.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4804)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 239, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 705)
[M::mem_pestat] mean and std.dev: (261.93, 126.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 886)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 419, 1165)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3143)
[M::mem_pestat] mean and std.dev: (623.00, 688.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4132)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 406, 1222)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3260)
[M::mem_pestat] mean and std.dev: (632.06, 579.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4279)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696570 sequences (100000121 bp) in 1.895 CPU sec, 1.990 real sec...
[M::mem_process_seqs] Processed 696806 reads in 192.183 CPU sec, 6.305 real sec
[M::mem_process_seqs] Processed 696514 reads in 130.817 CPU sec, 4.331 real sec
sorting block 53, #reads = 1073801 mem = 536879634 peak = 1000976384
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 282560, 14, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 244, 1271)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3483)
[M::mem_pestat] mean and std.dev: (906.84, 1155.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5530)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 238, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 708)
[M::mem_pestat] mean and std.dev: (262.58, 127.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 890)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (5, 215, 238)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 704)
[M::mem_pestat] mean and std.dev: (131.08, 135.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 937)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 346, 1219)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3273)
[M::mem_pestat] mean and std.dev: (698.19, 757.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4300)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 693982 sequences (100000140 bp) in 2.639 CPU sec, 3.099 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 281094, 28, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 503, 1576)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4360)
[M::mem_pestat] mean and std.dev: (759.26, 755.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5752)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 239, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 710)
[M::mem_pestat] mean and std.dev: (262.91, 128.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 893)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (89, 468, 767)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2123)
[M::mem_pestat] mean and std.dev: (462.74, 465.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2801)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 324, 786)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1986)
[M::mem_pestat] mean and std.dev: (390.09, 344.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2586)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696546 reads in 190.863 CPU sec, 6.376 real sec
[M::process] read 693676 sequences (100000191 bp) in 1.988 CPU sec, 2.111 real sec...
sorting block 54, #reads = 1073338 mem = 536877453 peak = 1000976384
[M::mem_process_seqs] Processed 696570 reads in 132.396 CPU sec, 4.613 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 280793, 14, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 378, 912)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2288)
[M::mem_pestat] mean and std.dev: (563.00, 427.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2976)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 247, 354)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 730)
[M::mem_pestat] mean and std.dev: (269.80, 130.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 918)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (508, 935, 1101)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2287)
[M::mem_pestat] mean and std.dev: (735.00, 425.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2880)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 370, 1016)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2606)
[M::mem_pestat] mean and std.dev: (505.87, 371.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3401)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 55, #reads = 1073376 mem = 536885163 peak = 1000976384
[M::process] read 695636 sequences (100000058 bp) in 2.757 CPU sec, 3.101 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 280867, 42, 82)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (336, 598, 1431)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3621)
[M::mem_pestat] mean and std.dev: (857.64, 575.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4716)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 250, 356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 732)
[M::mem_pestat] mean and std.dev: (271.83, 130.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 920)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (132, 491, 2545)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7371)
[M::mem_pestat] mean and std.dev: (1462.69, 1676.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9784)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (283, 548, 757)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1705)
[M::mem_pestat] mean and std.dev: (508.00, 297.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2179)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 693982 reads in 192.645 CPU sec, 6.531 real sec
[M::process] read 695814 sequences (100000150 bp) in 2.002 CPU sec, 2.135 real sec...
[M::mem_process_seqs] Processed 693676 reads in 132.207 CPU sec, 4.300 real sec
sorting block 56, #reads = 1071396 mem = 536880737 peak = 1000976384
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 281080, 24, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (269, 398, 1503)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3971)
[M::mem_pestat] mean and std.dev: (681.35, 731.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5205)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 240, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 703)
[M::mem_pestat] mean and std.dev: (262.74, 126.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 883)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (236, 466, 1296)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3416)
[M::mem_pestat] mean and std.dev: (615.43, 611.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4476)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 333, 762)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1842)
[M::mem_pestat] mean and std.dev: (443.92, 429.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2382)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695982 sequences (100000180 bp) in 2.550 CPU sec, 2.914 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 281328, 35, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (239, 341, 1150)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2972)
[M::mem_pestat] mean and std.dev: (586.12, 515.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3883)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 239, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 705)
[M::mem_pestat] mean and std.dev: (262.48, 127.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 886)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (569, 1382, 1592)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3638)
[M::mem_pestat] mean and std.dev: (1302.79, 957.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5135)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 518, 2224)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6274)
[M::mem_pestat] mean and std.dev: (1241.94, 1488.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8299)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695590 sequences (100000029 bp) in 1.937 CPU sec, 1.996 real sec...
[M::mem_process_seqs] Processed 695636 reads in 194.728 CPU sec, 6.496 real sec
[M::mem_process_seqs] Processed 695814 reads in 129.103 CPU sec, 4.252 real sec
sorting block 57, #reads = 1072180 mem = 536880970 peak = 1000976384
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 281703, 21, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 366, 1273)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3387)
[M::mem_pestat] mean and std.dev: (642.15, 656.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4444)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 239, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 705)
[M::mem_pestat] mean and std.dev: (262.62, 126.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 886)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (233, 339, 924)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2306)
[M::mem_pestat] mean and std.dev: (605.52, 501.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2997)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 282, 588)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1380)
[M::mem_pestat] mean and std.dev: (382.97, 326.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1776)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695900 sequences (100000253 bp) in 2.689 CPU sec, 3.157 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 281003, 34, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (140, 368, 656)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1688)
[M::mem_pestat] mean and std.dev: (382.09, 347.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2204)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 238, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 700)
[M::mem_pestat] mean and std.dev: (262.07, 126.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 879)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (146, 695, 802)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2114)
[M::mem_pestat] mean and std.dev: (572.34, 464.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2770)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 241, 1095)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3009)
[M::mem_pestat] mean and std.dev: (603.23, 692.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3966)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695982 reads in 190.266 CPU sec, 6.259 real sec
[M::process] read 695588 sequences (100000192 bp) in 1.811 CPU sec, 1.821 real sec...
sorting block 58, #reads = 1072552 mem = 536877547 peak = 1000976384
[M::mem_process_seqs] Processed 695590 reads in 130.769 CPU sec, 4.171 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 280949, 28, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 340, 963)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2507)
[M::mem_pestat] mean and std.dev: (463.03, 451.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3279)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 238, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 696)
[M::mem_pestat] mean and std.dev: (260.78, 125.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 874)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (287, 876, 1987)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5387)
[M::mem_pestat] mean and std.dev: (1017.44, 864.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7087)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (305, 629, 1245)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3125)
[M::mem_pestat] mean and std.dev: (748.84, 565.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4065)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 59, #reads = 1072994 mem = 536880939 peak = 1013862400
[M::process] read 695818 sequences (100000097 bp) in 2.798 CPU sec, 3.152 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 281373, 24, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 324, 1154)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3116)
[M::mem_pestat] mean and std.dev: (652.04, 648.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4097)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 239, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 697)
[M::mem_pestat] mean and std.dev: (261.61, 125.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 875)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (295, 546, 960)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2290)
[M::mem_pestat] mean and std.dev: (431.75, 326.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2955)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 245, 750)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1880)
[M::mem_pestat] mean and std.dev: (407.78, 371.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2445)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696050 sequences (100000282 bp) in 1.898 CPU sec, 1.926 real sec...
[M::mem_process_seqs] Processed 695900 reads in 194.103 CPU sec, 6.362 real sec
[M::mem_process_seqs] Processed 695588 reads in 129.300 CPU sec, 4.200 real sec
sorting block 60, #reads = 1072741 mem = 536880535 peak = 1013862400
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 281190, 28, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 326, 632)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1534)
[M::mem_pestat] mean and std.dev: (308.30, 237.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1985)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 237, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 690)
[M::mem_pestat] mean and std.dev: (259.92, 124.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 866)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (462, 846, 1372)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3192)
[M::mem_pestat] mean and std.dev: (978.86, 701.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4102)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 345, 1066)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2810)
[M::mem_pestat] mean and std.dev: (645.31, 659.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3682)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696046 sequences (100000297 bp) in 2.396 CPU sec, 2.715 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 281392, 30, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 383, 713)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1785)
[M::mem_pestat] mean and std.dev: (390.07, 311.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2321)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 237, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 693)
[M::mem_pestat] mean and std.dev: (260.12, 125.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 870)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (616, 746, 2239)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5485)
[M::mem_pestat] mean and std.dev: (1137.93, 1084.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7108)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 351, 1191)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3167)
[M::mem_pestat] mean and std.dev: (582.95, 617.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4155)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695980 sequences (100000194 bp) in 1.821 CPU sec, 1.829 real sec...
[M::mem_process_seqs] Processed 695818 reads in 193.947 CPU sec, 6.341 real sec
[M::mem_process_seqs] Processed 696050 reads in 130.806 CPU sec, 4.221 real sec
sorting block 61, #reads = 1073268 mem = 536880380 peak = 1013862400
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 281085, 42, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 704, 1195)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3251)
[M::mem_pestat] mean and std.dev: (843.28, 865.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4307)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 237, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 687)
[M::mem_pestat] mean and std.dev: (259.15, 123.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 862)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 456, 1702)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4666)
[M::mem_pestat] mean and std.dev: (1035.03, 1235.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6148)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (242, 526, 815)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1961)
[M::mem_pestat] mean and std.dev: (487.95, 420.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2534)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695996 sequences (100000198 bp) in 2.767 CPU sec, 3.205 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 281340, 41, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 475, 1149)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3025)
[M::mem_pestat] mean and std.dev: (651.39, 554.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3963)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 236, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 690)
[M::mem_pestat] mean and std.dev: (259.81, 125.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 866)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (289, 500, 1151)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2875)
[M::mem_pestat] mean and std.dev: (629.46, 633.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3737)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (325, 537, 1711)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4483)
[M::mem_pestat] mean and std.dev: (956.32, 830.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5869)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695938 sequences (100000285 bp) in 1.964 CPU sec, 1.974 real sec...
[M::mem_process_seqs] Processed 696046 reads in 192.289 CPU sec, 6.216 real sec
sorting block 62, #reads = 1072481 mem = 536878173 peak = 1013862400
[M::mem_process_seqs] Processed 695980 reads in 132.116 CPU sec, 4.448 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 281728, 17, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 352, 1278)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3406)
[M::mem_pestat] mean and std.dev: (605.40, 536.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4470)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 238, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 693)
[M::mem_pestat] mean and std.dev: (260.36, 124.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 870)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (107, 688, 8770)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 26096)
[M::mem_pestat] mean and std.dev: (2618.59, 3466.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 34759)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 262, 368)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 788)
[M::mem_pestat] mean and std.dev: (250.59, 122.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 998)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696048 sequences (100000291 bp) in 2.805 CPU sec, 3.111 real sec...
sorting block 63, #reads = 1073255 mem = 536883302 peak = 1013862400
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 281382, 31, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 290, 1766)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4946)
[M::mem_pestat] mean and std.dev: (889.41, 1158.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6536)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 237, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 693)
[M::mem_pestat] mean and std.dev: (260.37, 125.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 870)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (477, 886, 1381)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3189)
[M::mem_pestat] mean and std.dev: (1046.19, 845.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4428)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (261, 419, 1094)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2760)
[M::mem_pestat] mean and std.dev: (690.84, 680.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3593)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695492 sequences (100000278 bp) in 1.746 CPU sec, 1.817 real sec...
[M::mem_process_seqs] Processed 695996 reads in 194.742 CPU sec, 6.552 real sec
[M::mem_process_seqs] Processed 695938 reads in 128.165 CPU sec, 4.183 real sec
sorting block 64, #reads = 1073400 mem = 536878754 peak = 1013862400
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 280840, 27, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (246, 388, 1103)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2817)
[M::mem_pestat] mean and std.dev: (792.86, 694.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3674)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 237, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 696)
[M::mem_pestat] mean and std.dev: (260.67, 126.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 874)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (284, 778, 1103)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2741)
[M::mem_pestat] mean and std.dev: (694.15, 419.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3560)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (231, 307, 575)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1263)
[M::mem_pestat] mean and std.dev: (423.69, 262.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1607)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695958 sequences (100000174 bp) in 2.702 CPU sec, 2.945 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 281312, 23, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 450, 754)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1848)
[M::mem_pestat] mean and std.dev: (499.44, 404.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2395)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 239, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 700)
[M::mem_pestat] mean and std.dev: (262.06, 126.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 879)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (117, 429, 1614)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4608)
[M::mem_pestat] mean and std.dev: (809.73, 989.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6105)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (273, 536, 861)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2037)
[M::mem_pestat] mean and std.dev: (568.80, 438.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2625)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696036 sequences (100000117 bp) in 1.896 CPU sec, 1.898 real sec...
[M::mem_process_seqs] Processed 696048 reads in 192.995 CPU sec, 6.333 real sec
[M::mem_process_seqs] Processed 695492 reads in 131.611 CPU sec, 4.310 real sec
sorting block 65, #reads = 1073026 mem = 536880937 peak = 1013862400
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 281548, 42, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 452, 853)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2097)
[M::mem_pestat] mean and std.dev: (471.37, 365.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2719)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 237, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 693)
[M::mem_pestat] mean and std.dev: (260.42, 125.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 870)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 1006, 1791)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4939)
[M::mem_pestat] mean and std.dev: (1307.98, 1280.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6513)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 299, 550)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1252)
[M::mem_pestat] mean and std.dev: (334.70, 248.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1603)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697838 sequences (100000011 bp) in 2.661 CPU sec, 2.960 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 281526, 21, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 307, 1195)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3271)
[M::mem_pestat] mean and std.dev: (699.28, 794.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4309)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 236, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 695)
[M::mem_pestat] mean and std.dev: (260.22, 126.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 873)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (419, 917, 1850)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4712)
[M::mem_pestat] mean and std.dev: (1044.57, 830.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6143)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 245, 702)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1746)
[M::mem_pestat] mean and std.dev: (329.67, 244.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2268)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695556 sequences (100000277 bp) in 1.607 CPU sec, 1.713 real sec...
[M::mem_process_seqs] Processed 695958 reads in 194.298 CPU sec, 6.271 real sec
sorting block 66, #reads = 1071877 mem = 536876894 peak = 1013862400
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 281627, 33, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 270, 453)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1025)
[M::mem_pestat] mean and std.dev: (275.50, 160.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1311)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 235, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 696)
[M::mem_pestat] mean and std.dev: (258.00, 124.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 875)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (422, 825, 1535)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3761)
[M::mem_pestat] mean and std.dev: (844.19, 474.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4874)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 333, 630)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1528)
[M::mem_pestat] mean and std.dev: (426.97, 377.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1977)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695400 sequences (100000219 bp) in 2.416 CPU sec, 2.465 real sec...
[M::mem_process_seqs] Processed 697838 reads in 111.489 CPU sec, 3.551 real sec
[M::mem_process_seqs] Processed 696036 reads in 288.331 CPU sec, 9.244 real sec
sorting block 67, #reads = 1072777 mem = 536881435 peak = 1013862400
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 281221, 43, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (232, 268, 1066)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2734)
[M::mem_pestat] mean and std.dev: (599.06, 663.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3568)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 241, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 700)
[M::mem_pestat] mean and std.dev: (262.38, 124.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 879)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (261, 735, 1492)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3954)
[M::mem_pestat] mean and std.dev: (1022.02, 1122.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5514)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (264, 449, 788)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1836)
[M::mem_pestat] mean and std.dev: (497.07, 351.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2360)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694586 sequences (100000117 bp) in 2.670 CPU sec, 3.004 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 280810, 14, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 247, 1010)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2660)
[M::mem_pestat] mean and std.dev: (653.71, 712.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3502)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 244, 348)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 716)
[M::mem_pestat] mean and std.dev: (265.69, 127.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 900)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 853, 3689)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10619)
[M::mem_pestat] mean and std.dev: (1353.50, 1517.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14084)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (278, 490, 1293)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3323)
[M::mem_pestat] mean and std.dev: (707.50, 557.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4338)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695556 reads in 210.198 CPU sec, 6.765 real sec
[M::mem_process_seqs] Processed 695400 reads in 132.248 CPU sec, 4.244 real sec
[M::process] read 695304 sequences (100000266 bp) in 2.268 CPU sec, 2.429 real sec...
sorting block 68, #reads = 1070683 mem = 536881878 peak = 1013862400
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 280988, 7, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (238, 707, 1302)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3430)
[M::mem_pestat] mean and std.dev: (817.60, 600.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4494)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 245, 348)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 714)
[M::mem_pestat] mean and std.dev: (266.40, 126.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 897)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 226, 572)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1406)
[M::mem_pestat] mean and std.dev: (314.66, 255.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1823)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 696198 sequences (100000260 bp) in 2.190 CPU sec, 2.607 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 281040, 30, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (249, 394, 870)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2112)
[M::mem_pestat] mean and std.dev: (570.81, 453.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2733)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 243, 345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 707)
[M::mem_pestat] mean and std.dev: (264.04, 126.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 888)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 285, 668)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1618)
[M::mem_pestat] mean and std.dev: (391.59, 325.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2093)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 266, 665)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1701)
[M::mem_pestat] mean and std.dev: (436.00, 386.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2219)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 694586 reads in 184.047 CPU sec, 5.963 real sec
sorting block 69, #reads = 1073697 mem = 536879813 peak = 1018740736
[M::mem_process_seqs] Processed 695304 reads in 128.518 CPU sec, 4.117 real sec
[M::process] read 696122 sequences (100000251 bp) in 2.558 CPU sec, 2.857 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 281526, 21, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (368, 542, 661)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1247)
[M::mem_pestat] mean and std.dev: (464.18, 214.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1540)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 238, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 696)
[M::mem_pestat] mean and std.dev: (260.37, 124.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 874)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (235, 1065, 2587)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7291)
[M::mem_pestat] mean and std.dev: (1251.70, 1277.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9643)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (290, 373, 817)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1871)
[M::mem_pestat] mean and std.dev: (511.76, 321.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2398)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 70, #reads = 1074010 mem = 536880111 peak = 1018740736
[M::process] read 695180 sequences (100000091 bp) in 2.841 CPU sec, 3.191 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 281663, 12, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (265, 639, 1499)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3967)
[M::mem_pestat] mean and std.dev: (915.75, 842.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5201)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 240, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 705)
[M::mem_pestat] mean and std.dev: (261.91, 125.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 886)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (439, 688, 1547)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3763)
[M::mem_pestat] mean and std.dev: (973.82, 869.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4871)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 334, 810)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2138)
[M::mem_pestat] mean and std.dev: (427.10, 388.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2802)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696198 reads in 183.396 CPU sec, 5.972 real sec
[M::process] read 693510 sequences (100000045 bp) in 1.983 CPU sec, 2.069 real sec...
[M::mem_process_seqs] Processed 696122 reads in 127.814 CPU sec, 4.311 real sec
sorting block 71, #reads = 1075044 mem = 536880748 peak = 1018740736
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 281253, 25, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (225, 469, 1592)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4326)
[M::mem_pestat] mean and std.dev: (861.39, 902.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5693)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 244, 350)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 722)
[M::mem_pestat] mean and std.dev: (266.69, 128.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 908)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (16, 217, 820)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2428)
[M::mem_pestat] mean and std.dev: (494.48, 595.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3232)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 292, 466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1076)
[M::mem_pestat] mean and std.dev: (302.44, 172.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1381)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695438 sequences (100000033 bp) in 2.344 CPU sec, 2.683 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 280710, 46, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 223, 465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1033)
[M::mem_pestat] mean and std.dev: (266.15, 143.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1317)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 251, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 741)
[M::mem_pestat] mean and std.dev: (272.87, 131.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 932)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (270, 866, 1165)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2955)
[M::mem_pestat] mean and std.dev: (879.71, 700.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3850)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 323, 907)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2301)
[M::mem_pestat] mean and std.dev: (574.18, 586.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2998)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695180 reads in 181.212 CPU sec, 6.087 real sec
[M::process] read 697332 sequences (100000147 bp) in 2.145 CPU sec, 2.252 real sec...
[M::mem_process_seqs] Processed 693510 reads in 126.886 CPU sec, 4.298 real sec
sorting block 72, #reads = 1073458 mem = 536878985 peak = 1018740736
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 281303, 29, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 285, 476)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1112)
[M::mem_pestat] mean and std.dev: (264.22, 169.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1430)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 242, 348)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 718)
[M::mem_pestat] mean and std.dev: (265.21, 128.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 903)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (475, 541, 1163)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2539)
[M::mem_pestat] mean and std.dev: (673.04, 451.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3227)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (253, 379, 1240)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3214)
[M::mem_pestat] mean and std.dev: (618.08, 561.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4201)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697636 sequences (100000257 bp) in 2.321 CPU sec, 2.683 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 281850, 36, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (259, 685, 1889)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5149)
[M::mem_pestat] mean and std.dev: (849.00, 903.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6779)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 237, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 700)
[M::mem_pestat] mean and std.dev: (259.93, 125.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 880)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (353, 622, 1119)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2651)
[M::mem_pestat] mean and std.dev: (604.23, 441.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3417)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 310, 460)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1048)
[M::mem_pestat] mean and std.dev: (313.55, 193.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1342)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697486 sequences (100000300 bp) in 1.881 CPU sec, 1.989 real sec...
[M::mem_process_seqs] Processed 695438 reads in 186.502 CPU sec, 6.214 real sec
sorting block 73, #reads = 1072653 mem = 536878181 peak = 1018740736
[M::mem_process_seqs] Processed 697332 reads in 128.262 CPU sec, 4.149 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 281477, 26, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (123, 254, 484)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1206)
[M::mem_pestat] mean and std.dev: (318.84, 273.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1567)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 236, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 706)
[M::mem_pestat] mean and std.dev: (260.71, 127.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 888)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (584, 808, 1453)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3191)
[M::mem_pestat] mean and std.dev: (710.57, 430.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4060)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 353, 845)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2163)
[M::mem_pestat] mean and std.dev: (564.14, 585.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2905)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 74, #reads = 1073923 mem = 536879666 peak = 1018740736
[M::process] read 697366 sequences (100000226 bp) in 2.677 CPU sec, 2.970 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 281924, 15, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 297, 771)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1933)
[M::mem_pestat] mean and std.dev: (445.37, 334.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2514)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 236, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 700)
[M::mem_pestat] mean and std.dev: (259.45, 125.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 880)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (69, 388, 1084)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3114)
[M::mem_pestat] mean and std.dev: (543.29, 509.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4129)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 328, 614)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1474)
[M::mem_pestat] mean and std.dev: (415.34, 330.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1904)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697636 reads in 189.023 CPU sec, 6.250 real sec
[M::process] read 697132 sequences (100000227 bp) in 2.034 CPU sec, 2.068 real sec...
[M::mem_process_seqs] Processed 697486 reads in 131.307 CPU sec, 4.296 real sec
sorting block 75, #reads = 1073310 mem = 536881613 peak = 1018740736
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 282158, 14, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 384, 887)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2337)
[M::mem_pestat] mean and std.dev: (498.45, 394.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3062)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 236, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 697)
[M::mem_pestat] mean and std.dev: (259.13, 125.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 876)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (94, 526, 1808)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5236)
[M::mem_pestat] mean and std.dev: (781.86, 852.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6950)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (409, 627, 1284)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3034)
[M::mem_pestat] mean and std.dev: (809.31, 682.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3909)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697962 sequences (100000224 bp) in 2.623 CPU sec, 3.048 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 282121, 36, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (234, 356, 801)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1935)
[M::mem_pestat] mean and std.dev: (419.62, 340.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2502)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 237, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 700)
[M::mem_pestat] mean and std.dev: (260.08, 126.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 880)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (256, 523, 1531)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4081)
[M::mem_pestat] mean and std.dev: (783.69, 828.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5356)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 266, 386)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 762)
[M::mem_pestat] mean and std.dev: (280.75, 126.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 950)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696834 sequences (100000187 bp) in 1.998 CPU sec, 2.003 real sec...
[M::mem_process_seqs] Processed 697366 reads in 189.322 CPU sec, 6.129 real sec
[M::mem_process_seqs] Processed 697132 reads in 130.178 CPU sec, 4.208 real sec
sorting block 76, #reads = 1073202 mem = 536879799 peak = 1018740736
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 281828, 25, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 323, 2716)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7796)
[M::mem_pestat] mean and std.dev: (1387.61, 1778.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10336)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 235, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 697)
[M::mem_pestat] mean and std.dev: (259.17, 126.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 876)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (242, 1199, 3264)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9308)
[M::mem_pestat] mean and std.dev: (1545.08, 1483.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12330)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (262, 387, 1585)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4231)
[M::mem_pestat] mean and std.dev: (869.09, 926.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5554)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696454 sequences (100000122 bp) in 2.694 CPU sec, 3.304 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (73, 281746, 21, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 451, 1565)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4277)
[M::mem_pestat] mean and std.dev: (973.84, 1096.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5633)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 237, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 701)
[M::mem_pestat] mean and std.dev: (261.07, 126.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 881)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 671, 1077)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2889)
[M::mem_pestat] mean and std.dev: (716.43, 614.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3795)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 265, 401)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 829)
[M::mem_pestat] mean and std.dev: (294.06, 170.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1043)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 693970 sequences (100000088 bp) in 1.859 CPU sec, 1.861 real sec...
[M::mem_process_seqs] Processed 697962 reads in 197.324 CPU sec, 6.487 real sec
sorting block 77, #reads = 1073648 mem = 536880623 peak = 1018740736
[M::mem_process_seqs] Processed 696834 reads in 133.364 CPU sec, 4.346 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 281624, 26, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 343, 862)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2278)
[M::mem_pestat] mean and std.dev: (502.71, 420.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2986)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 239, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 708)
[M::mem_pestat] mean and std.dev: (262.69, 127.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 890)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (236, 446, 676)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1556)
[M::mem_pestat] mean and std.dev: (422.71, 233.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1996)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 427, 1153)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3081)
[M::mem_pestat] mean and std.dev: (659.70, 603.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4045)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 78, #reads = 1073621 mem = 536881179 peak = 1065951232
[M::process] read 695578 sequences (100000173 bp) in 2.804 CPU sec, 3.285 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 281219, 25, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 402, 907)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2363)
[M::mem_pestat] mean and std.dev: (537.62, 418.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3091)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 249, 356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 734)
[M::mem_pestat] mean and std.dev: (271.23, 131.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 923)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (227, 722, 2869)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8153)
[M::mem_pestat] mean and std.dev: (1228.12, 1448.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10795)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (390, 540, 815)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1665)
[M::mem_pestat] mean and std.dev: (527.94, 278.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2090)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696186 sequences (100000145 bp) in 1.904 CPU sec, 1.915 real sec...
[M::mem_process_seqs] Processed 696454 reads in 187.109 CPU sec, 6.133 real sec
[M::mem_process_seqs] Processed 693970 reads in 126.956 CPU sec, 4.172 real sec
sorting block 79, #reads = 1073870 mem = 536875626 peak = 1065951232
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 281210, 26, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (254, 331, 769)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1799)
[M::mem_pestat] mean and std.dev: (412.00, 319.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2314)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 242, 348)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 716)
[M::mem_pestat] mean and std.dev: (265.73, 128.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 900)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (62, 1191, 1925)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5651)
[M::mem_pestat] mean and std.dev: (1089.09, 1346.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7514)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (285, 471, 2002)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5436)
[M::mem_pestat] mean and std.dev: (1046.56, 1217.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7153)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696362 sequences (100000178 bp) in 2.798 CPU sec, 3.370 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 281468, 32, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (240, 459, 770)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1830)
[M::mem_pestat] mean and std.dev: (464.88, 343.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2360)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 238, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 702)
[M::mem_pestat] mean and std.dev: (261.87, 126.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 882)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 529, 838)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2130)
[M::mem_pestat] mean and std.dev: (494.53, 411.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2776)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 330, 1063)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2747)
[M::mem_pestat] mean and std.dev: (622.10, 626.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3589)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695578 reads in 189.416 CPU sec, 6.242 real sec
[M::process] read 695294 sequences (100000093 bp) in 2.012 CPU sec, 2.034 real sec...
[M::mem_process_seqs] Processed 696186 reads in 128.591 CPU sec, 4.359 real sec
sorting block 80, #reads = 1074102 mem = 536878575 peak = 1065951232
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 281142, 25, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 393, 1920)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5440)
[M::mem_pestat] mean and std.dev: (984.61, 1167.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7200)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 238, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 702)
[M::mem_pestat] mean and std.dev: (261.67, 126.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 882)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (521, 1244, 2581)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6701)
[M::mem_pestat] mean and std.dev: (1447.84, 1195.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8761)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (241, 361, 689)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1585)
[M::mem_pestat] mean and std.dev: (465.15, 335.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2033)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694968 sequences (100000187 bp) in 2.809 CPU sec, 3.254 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 281321, 32, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (280, 429, 1617)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4291)
[M::mem_pestat] mean and std.dev: (892.94, 1031.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5628)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 243, 348)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 716)
[M::mem_pestat] mean and std.dev: (265.96, 128.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 900)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 844, 1431)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3933)
[M::mem_pestat] mean and std.dev: (773.17, 754.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5184)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (247, 309, 927)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2287)
[M::mem_pestat] mean and std.dev: (647.05, 647.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3238)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695924 sequences (100000201 bp) in 1.981 CPU sec, 2.000 real sec...
[M::mem_process_seqs] Processed 696362 reads in 197.174 CPU sec, 6.612 real sec
sorting block 81, #reads = 1070623 mem = 536881333 peak = 1065951232
[M::mem_process_seqs] Processed 695294 reads in 127.914 CPU sec, 4.196 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 281299, 14, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 323, 544)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1218)
[M::mem_pestat] mean and std.dev: (382.31, 251.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1555)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 243, 349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 719)
[M::mem_pestat] mean and std.dev: (266.55, 129.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 904)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (342, 1566, 1794)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4698)
[M::mem_pestat] mean and std.dev: (1142.58, 1091.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6150)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 240, 1359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3733)
[M::mem_pestat] mean and std.dev: (731.00, 765.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4920)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695960 sequences (100000298 bp) in 2.996 CPU sec, 3.384 real sec...
sorting block 82, #reads = 1072076 mem = 536879522 peak = 1065951232
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 281313, 35, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (329, 569, 1385)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3497)
[M::mem_pestat] mean and std.dev: (763.32, 623.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4553)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 239, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 700)
[M::mem_pestat] mean and std.dev: (262.20, 126.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 879)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (490, 633, 1713)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4159)
[M::mem_pestat] mean and std.dev: (881.79, 800.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5382)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (251, 401, 889)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2165)
[M::mem_pestat] mean and std.dev: (572.62, 480.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2803)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 694968 reads in 192.890 CPU sec, 6.336 real sec
[M::process] read 696406 sequences (100000041 bp) in 1.983 CPU sec, 2.065 real sec...
[M::mem_process_seqs] Processed 695924 reads in 130.528 CPU sec, 4.219 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 281328, 33, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 326, 782)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1926)
[M::mem_pestat] mean and std.dev: (407.42, 340.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2498)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 238, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 699)
[M::mem_pestat] mean and std.dev: (261.64, 126.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 878)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (481, 1055, 2647)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6979)
[M::mem_pestat] mean and std.dev: (1229.83, 1147.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9145)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 409, 918)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2340)
[M::mem_pestat] mean and std.dev: (500.40, 398.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3051)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 83, #reads = 1071528 mem = 536879202 peak = 1065951232
[M::process] read 696018 sequences (100000028 bp) in 2.769 CPU sec, 3.403 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 281276, 33, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 348, 1139)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3083)
[M::mem_pestat] mean and std.dev: (501.63, 407.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4055)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 237, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 689)
[M::mem_pestat] mean and std.dev: (259.05, 124.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 865)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 730, 1100)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2946)
[M::mem_pestat] mean and std.dev: (814.40, 858.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4248)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (256, 504, 1310)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3418)
[M::mem_pestat] mean and std.dev: (788.57, 756.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4472)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696142 sequences (100000039 bp) in 1.727 CPU sec, 1.807 real sec...
[M::mem_process_seqs] Processed 695960 reads in 195.331 CPU sec, 6.355 real sec
[M::mem_process_seqs] Processed 696406 reads in 131.165 CPU sec, 4.263 real sec
sorting block 84, #reads = 1071503 mem = 536882037 peak = 1065951232
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 281523, 17, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 211, 541)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1319)
[M::mem_pestat] mean and std.dev: (359.87, 303.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1708)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 236, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 687)
[M::mem_pestat] mean and std.dev: (259.07, 124.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 862)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (101, 486, 1373)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3917)
[M::mem_pestat] mean and std.dev: (599.38, 623.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5189)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (259, 628, 1352)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3538)
[M::mem_pestat] mean and std.dev: (735.88, 732.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4631)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696324 sequences (100000179 bp) in 2.671 CPU sec, 3.193 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 280895, 21, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 323, 829)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2123)
[M::mem_pestat] mean and std.dev: (478.02, 345.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2770)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 237, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 690)
[M::mem_pestat] mean and std.dev: (259.60, 124.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 866)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (480, 980, 1830)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4530)
[M::mem_pestat] mean and std.dev: (1044.26, 888.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5880)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 359, 582)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1340)
[M::mem_pestat] mean and std.dev: (410.84, 292.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1719)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696210 sequences (100000075 bp) in 1.964 CPU sec, 1.994 real sec...
[M::mem_process_seqs] Processed 696018 reads in 195.140 CPU sec, 6.363 real sec
[M::mem_process_seqs] Processed 696142 reads in 132.228 CPU sec, 4.484 real sec
sorting block 85, #reads = 1071899 mem = 536877150 peak = 1065951232
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 281672, 24, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 422, 697)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1659)
[M::mem_pestat] mean and std.dev: (499.69, 347.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2140)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 236, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 689)
[M::mem_pestat] mean and std.dev: (259.03, 124.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 865)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (399, 796, 4060)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 11382)
[M::mem_pestat] mean and std.dev: (1960.33, 2623.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 15043)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 343, 987)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2549)
[M::mem_pestat] mean and std.dev: (573.08, 499.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3330)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696242 sequences (100000054 bp) in 2.603 CPU sec, 3.038 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 281402, 26, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 282, 642)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1506)
[M::mem_pestat] mean and std.dev: (402.40, 316.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1938)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 236, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 690)
[M::mem_pestat] mean and std.dev: (259.11, 124.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 866)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (453, 801, 941)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1917)
[M::mem_pestat] mean and std.dev: (599.24, 317.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2405)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 465, 931)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2385)
[M::mem_pestat] mean and std.dev: (489.64, 417.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3112)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696142 sequences (100000248 bp) in 1.801 CPU sec, 1.868 real sec...
[M::mem_process_seqs] Processed 696324 reads in 200.550 CPU sec, 6.742 real sec
sorting block 86, #reads = 1071241 mem = 536877934 peak = 1065951232
[M::mem_process_seqs] Processed 696210 reads in 131.068 CPU sec, 4.239 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 281446, 16, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (132, 277, 521)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1299)
[M::mem_pestat] mean and std.dev: (304.76, 244.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1688)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 237, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 693)
[M::mem_pestat] mean and std.dev: (260.18, 125.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 870)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (431, 1067, 1692)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4214)
[M::mem_pestat] mean and std.dev: (1162.38, 887.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5475)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (251, 384, 1011)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2531)
[M::mem_pestat] mean and std.dev: (550.92, 474.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3291)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 87, #reads = 1071942 mem = 536882203 peak = 1065951232
[M::process] read 695894 sequences (100000205 bp) in 2.490 CPU sec, 3.045 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 281714, 33, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 446, 1614)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4458)
[M::mem_pestat] mean and std.dev: (818.12, 875.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5880)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 237, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 696)
[M::mem_pestat] mean and std.dev: (260.49, 125.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 874)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 661, 1149)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3099)
[M::mem_pestat] mean and std.dev: (718.94, 596.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4074)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (241, 457, 892)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2194)
[M::mem_pestat] mean and std.dev: (560.21, 429.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2845)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696650 sequences (100000009 bp) in 1.983 CPU sec, 2.073 real sec...
[M::mem_process_seqs] Processed 696242 reads in 195.858 CPU sec, 6.398 real sec
[M::mem_process_seqs] Processed 696142 reads in 131.806 CPU sec, 4.496 real sec
sorting block 88, #reads = 1071418 mem = 536881678 peak = 1065951232
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 280773, 19, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 282, 626)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1542)
[M::mem_pestat] mean and std.dev: (308.96, 255.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2000)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 238, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 693)
[M::mem_pestat] mean and std.dev: (260.59, 125.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 870)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (352, 486, 624)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1168)
[M::mem_pestat] mean and std.dev: (395.47, 142.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1440)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 258, 623)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1467)
[M::mem_pestat] mean and std.dev: (364.98, 236.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1889)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703900 sequences (100000182 bp) in 2.935 CPU sec, 3.329 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 281499, 32, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (143, 225, 862)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2300)
[M::mem_pestat] mean and std.dev: (560.69, 661.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3206)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 233, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 682)
[M::mem_pestat] mean and std.dev: (256.99, 123.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 856)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (418, 569, 924)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1936)
[M::mem_pestat] mean and std.dev: (639.00, 433.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2442)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 292, 638)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1552)
[M::mem_pestat] mean and std.dev: (375.59, 249.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2009)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700154 sequences (100000253 bp) in 2.000 CPU sec, 2.057 real sec...
[M::mem_process_seqs] Processed 695894 reads in 201.203 CPU sec, 6.748 real sec
[M::mem_process_seqs] Processed 696650 reads in 131.834 CPU sec, 4.247 real sec
sorting block 89, #reads = 1072001 mem = 536880350 peak = 1065951232
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 283999, 22, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 401, 808)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2022)
[M::mem_pestat] mean and std.dev: (516.87, 437.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2629)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 216, 313)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 639)
[M::mem_pestat] mean and std.dev: (241.39, 118.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 802)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (285, 698, 1439)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3747)
[M::mem_pestat] mean and std.dev: (843.81, 761.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4901)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 401, 862)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2142)
[M::mem_pestat] mean and std.dev: (487.23, 417.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2782)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700564 sequences (100000001 bp) in 2.703 CPU sec, 3.212 real sec...
[M::process] read 700954 sequences (100000018 bp) in 1.915 CPU sec, 1.922 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 282916, 17, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 295, 803)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2045)
[M::mem_pestat] mean and std.dev: (457.21, 474.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2666)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 227, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 687)
[M::mem_pestat] mean and std.dev: (254.86, 127.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 864)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (259, 662, 1265)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3277)
[M::mem_pestat] mean and std.dev: (816.65, 716.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4283)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (264, 827, 1136)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2880)
[M::mem_pestat] mean and std.dev: (779.60, 582.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3752)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703900 reads in 213.567 CPU sec, 6.924 real sec
sorting block 90, #reads = 1070862 mem = 536877841 peak = 1065951232
[M::mem_process_seqs] Processed 700154 reads in 140.726 CPU sec, 4.536 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 283727, 18, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 408, 1667)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4587)
[M::mem_pestat] mean and std.dev: (913.45, 847.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6047)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 227, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 689)
[M::mem_pestat] mean and std.dev: (254.38, 127.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 867)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (270, 571, 1946)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5298)
[M::mem_pestat] mean and std.dev: (841.82, 731.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6974)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 476, 771)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1881)
[M::mem_pestat] mean and std.dev: (467.06, 301.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2436)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 91, #reads = 1070381 mem = 536885936 peak = 1065951232
[M::process] read 701776 sequences (100000109 bp) in 2.650 CPU sec, 3.169 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 283385, 13, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 248, 582)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1392)
[M::mem_pestat] mean and std.dev: (366.53, 334.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1797)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 225, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 682)
[M::mem_pestat] mean and std.dev: (252.11, 125.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 858)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (228, 295, 850)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2094)
[M::mem_pestat] mean and std.dev: (458.92, 383.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2716)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (230, 352, 1875)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5165)
[M::mem_pestat] mean and std.dev: (976.03, 1029.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6810)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701284 sequences (100000078 bp) in 1.993 CPU sec, 2.006 real sec...
[M::mem_process_seqs] Processed 700564 reads in 208.165 CPU sec, 6.815 real sec
[M::mem_process_seqs] Processed 700954 reads in 137.570 CPU sec, 4.425 real sec
sorting block 92, #reads = 1071857 mem = 536882350 peak = 1065951232
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 283729, 24, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 313, 853)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2225)
[M::mem_pestat] mean and std.dev: (435.42, 489.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2911)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 222, 323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 663)
[M::mem_pestat] mean and std.dev: (248.23, 122.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 833)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 551, 1505)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4201)
[M::mem_pestat] mean and std.dev: (734.59, 768.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5549)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (243, 394, 1217)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3165)
[M::mem_pestat] mean and std.dev: (589.41, 666.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4139)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701486 sequences (100000150 bp) in 2.650 CPU sec, 3.101 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 283831, 15, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 326, 1122)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2958)
[M::mem_pestat] mean and std.dev: (561.59, 615.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3876)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 223, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 667)
[M::mem_pestat] mean and std.dev: (249.47, 123.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 838)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (560, 1196, 2143)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5309)
[M::mem_pestat] mean and std.dev: (1526.60, 1346.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6911)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 466, 1228)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3254)
[M::mem_pestat] mean and std.dev: (660.47, 673.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4267)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700968 sequences (100000196 bp) in 2.095 CPU sec, 2.099 real sec...
[M::mem_process_seqs] Processed 701776 reads in 203.779 CPU sec, 6.624 real sec
[M::mem_process_seqs] Processed 701284 reads in 137.856 CPU sec, 4.698 real sec
sorting block 93, #reads = 1071786 mem = 536881300 peak = 1065951232
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 284322, 18, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 242, 544)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1302)
[M::mem_pestat] mean and std.dev: (326.77, 219.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1681)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 223, 323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 663)
[M::mem_pestat] mean and std.dev: (248.00, 121.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 833)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (270, 754, 908)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2184)
[M::mem_pestat] mean and std.dev: (481.07, 305.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2822)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (273, 365, 511)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 987)
[M::mem_pestat] mean and std.dev: (327.00, 131.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1225)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697382 sequences (100000185 bp) in 2.721 CPU sec, 3.107 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 283480, 28, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (145, 375, 1601)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4513)
[M::mem_pestat] mean and std.dev: (1015.98, 1243.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5989)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 223, 323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 661)
[M::mem_pestat] mean and std.dev: (248.34, 121.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 830)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (585, 909, 2397)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6021)
[M::mem_pestat] mean and std.dev: (1329.16, 1415.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7833)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 463, 573)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1329)
[M::mem_pestat] mean and std.dev: (418.94, 239.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1707)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699144 sequences (100000221 bp) in 2.045 CPU sec, 2.072 real sec...
[M::mem_process_seqs] Processed 701486 reads in 209.539 CPU sec, 7.070 real sec
sorting block 94, #reads = 1074473 mem = 536882413 peak = 1065951232
[M::mem_process_seqs] Processed 700968 reads in 141.738 CPU sec, 4.590 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 282087, 17, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 365, 1199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3173)
[M::mem_pestat] mean and std.dev: (637.14, 564.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4160)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 237, 346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 718)
[M::mem_pestat] mean and std.dev: (263.32, 130.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 904)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (522, 922, 6417)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 18207)
[M::mem_pestat] mean and std.dev: (2266.94, 2391.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 24102)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 267, 622)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1472)
[M::mem_pestat] mean and std.dev: (338.42, 244.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1897)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 95, #reads = 1075030 mem = 536879395 peak = 1065951232
[M::process] read 701250 sequences (100000270 bp) in 2.744 CPU sec, 3.104 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 282961, 34, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 326, 1039)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2733)
[M::mem_pestat] mean and std.dev: (559.24, 560.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3580)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 230, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 688)
[M::mem_pestat] mean and std.dev: (255.68, 125.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 865)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 714, 1160)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3100)
[M::mem_pestat] mean and std.dev: (715.16, 537.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4070)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (243, 510, 1292)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3390)
[M::mem_pestat] mean and std.dev: (717.12, 637.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4439)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701762 sequences (100000135 bp) in 1.984 CPU sec, 2.008 real sec...
[M::mem_process_seqs] Processed 697382 reads in 204.128 CPU sec, 6.640 real sec
[M::mem_process_seqs] Processed 699144 reads in 139.939 CPU sec, 4.498 real sec
sorting block 96, #reads = 1070893 mem = 536878674 peak = 1065951232
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 283825, 33, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 279, 788)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2060)
[M::mem_pestat] mean and std.dev: (417.16, 391.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2696)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 223, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 664)
[M::mem_pestat] mean and std.dev: (248.95, 122.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 834)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (357, 747, 2585)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7041)
[M::mem_pestat] mean and std.dev: (1059.67, 1113.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9269)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (322, 506, 1222)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3022)
[M::mem_pestat] mean and std.dev: (815.00, 664.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3922)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700702 sequences (100000164 bp) in 2.777 CPU sec, 3.189 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 283050, 22, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 516, 1512)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4198)
[M::mem_pestat] mean and std.dev: (766.78, 816.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5541)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 222, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 660)
[M::mem_pestat] mean and std.dev: (247.21, 121.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 829)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (375, 612, 1614)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4092)
[M::mem_pestat] mean and std.dev: (817.25, 686.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5331)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 273, 348)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 692)
[M::mem_pestat] mean and std.dev: (260.13, 113.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 864)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699878 sequences (100000171 bp) in 1.981 CPU sec, 1.995 real sec...
[M::mem_process_seqs] Processed 701250 reads in 209.054 CPU sec, 6.808 real sec
[M::mem_process_seqs] Processed 701762 reads in 150.927 CPU sec, 4.893 real sec
sorting block 97, #reads = 1073110 mem = 536885545 peak = 1065951232
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 283790, 18, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 408, 520)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1174)
[M::mem_pestat] mean and std.dev: (346.57, 176.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1501)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 224, 327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 673)
[M::mem_pestat] mean and std.dev: (250.93, 124.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 846)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 566, 1114)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3014)
[M::mem_pestat] mean and std.dev: (699.22, 630.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3964)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 252, 300)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 534)
[M::mem_pestat] mean and std.dev: (239.33, 78.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 651)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699126 sequences (100000037 bp) in 2.880 CPU sec, 3.343 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 282803, 30, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (252, 379, 2067)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5697)
[M::mem_pestat] mean and std.dev: (926.18, 1155.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7512)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 227, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 681)
[M::mem_pestat] mean and std.dev: (253.53, 125.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 856)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (661, 1254, 2607)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6499)
[M::mem_pestat] mean and std.dev: (1704.89, 1564.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8445)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (243, 445, 1187)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3075)
[M::mem_pestat] mean and std.dev: (636.37, 640.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4019)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695944 sequences (100000197 bp) in 1.964 CPU sec, 1.976 real sec...
[M::mem_process_seqs] Processed 700702 reads in 203.814 CPU sec, 6.621 real sec
sorting block 98, #reads = 1072266 mem = 536882028 peak = 1065951232
[M::mem_process_seqs] Processed 699878 reads in 136.696 CPU sec, 4.456 real sec
[M::process] read 697880 sequences (100000069 bp) in 2.649 CPU sec, 3.099 real sec...
sorting block 99, #reads = 1072691 mem = 536879542 peak = 1065951232
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 280645, 37, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 714, 1740)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4814)
[M::mem_pestat] mean and std.dev: (859.13, 1003.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6351)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 240, 349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 721)
[M::mem_pestat] mean and std.dev: (266.39, 131.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 907)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (337, 596, 1456)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3694)
[M::mem_pestat] mean and std.dev: (870.67, 858.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4813)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 396, 2812)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8026)
[M::mem_pestat] mean and std.dev: (1407.15, 1647.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10633)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698746 sequences (100000113 bp) in 2.120 CPU sec, 2.158 real sec...
[M::mem_process_seqs] Processed 695944 reads in 117.147 CPU sec, 3.775 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 282777, 31, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (139, 252, 426)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1000)
[M::mem_pestat] mean and std.dev: (240.19, 129.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1287)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 229, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 688)
[M::mem_pestat] mean and std.dev: (255.72, 126.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 865)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (520, 681, 1762)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4246)
[M::mem_pestat] mean and std.dev: (1081.13, 1014.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5488)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 383, 744)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1854)
[M::mem_pestat] mean and std.dev: (460.50, 330.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2409)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 281856, 20, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (290, 425, 1719)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4577)
[M::mem_pestat] mean and std.dev: (987.00, 1047.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6006)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 233, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 696)
[M::mem_pestat] mean and std.dev: (258.74, 127.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 875)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (342, 1047, 1433)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3615)
[M::mem_pestat] mean and std.dev: (868.90, 707.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4706)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (242, 400, 2028)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5600)
[M::mem_pestat] mean and std.dev: (1110.65, 1185.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7386)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699126 reads in 324.850 CPU sec, 10.541 real sec
[M::process] read 696708 sequences (100000071 bp) in 2.095 CPU sec, 2.163 real sec...
sorting block 100, #reads = 1068932 mem = 536881697 peak = 1065951232
[M::mem_process_seqs] Processed 697880 reads in 171.050 CPU sec, 5.728 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 282600, 18, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (266, 551, 1774)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4790)
[M::mem_pestat] mean and std.dev: (1119.22, 1259.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6298)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 230, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 689)
[M::mem_pestat] mean and std.dev: (256.47, 126.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 866)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (548, 1137, 2419)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6161)
[M::mem_pestat] mean and std.dev: (1450.06, 1231.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8032)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 469, 930)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2442)
[M::mem_pestat] mean and std.dev: (621.25, 572.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3198)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696892 sequences (100000196 bp) in 2.656 CPU sec, 3.105 real sec...
sorting block 101, #reads = 1070791 mem = 536886615 peak = 1065951232
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 281745, 21, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (234, 396, 1507)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4053)
[M::mem_pestat] mean and std.dev: (825.67, 1038.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5326)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 237, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 707)
[M::mem_pestat] mean and std.dev: (262.16, 128.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 889)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (566, 727, 1559)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3545)
[M::mem_pestat] mean and std.dev: (851.83, 429.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4538)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (251, 475, 1120)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2858)
[M::mem_pestat] mean and std.dev: (681.09, 581.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3727)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698746 reads in 206.122 CPU sec, 6.974 real sec
[M::process] read 696282 sequences (100000051 bp) in 2.137 CPU sec, 2.237 real sec...
[M::mem_process_seqs] Processed 696708 reads in 141.389 CPU sec, 4.739 real sec
sorting block 102, #reads = 1070070 mem = 536880897 peak = 1065951232
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 281309, 41, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (144, 224, 787)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2073)
[M::mem_pestat] mean and std.dev: (444.67, 418.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2716)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 235, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 695)
[M::mem_pestat] mean and std.dev: (260.09, 126.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 873)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (332, 819, 1750)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4586)
[M::mem_pestat] mean and std.dev: (991.85, 886.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6004)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 335, 573)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1311)
[M::mem_pestat] mean and std.dev: (342.16, 217.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1680)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697248 sequences (100000185 bp) in 2.663 CPU sec, 3.346 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 281246, 27, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 327, 1624)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4528)
[M::mem_pestat] mean and std.dev: (769.08, 914.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5980)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 237, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 699)
[M::mem_pestat] mean and std.dev: (261.15, 126.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 878)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (475, 804, 1791)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4423)
[M::mem_pestat] mean and std.dev: (854.42, 603.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5739)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 526, 1755)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4843)
[M::mem_pestat] mean and std.dev: (856.60, 973.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6387)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695848 sequences (100000141 bp) in 1.827 CPU sec, 1.849 real sec...
[M::mem_process_seqs] Processed 696892 reads in 213.291 CPU sec, 7.178 real sec
[M::mem_process_seqs] Processed 696282 reads in 144.909 CPU sec, 4.755 real sec
sorting block 103, #reads = 1068803 mem = 536879964 peak = 1065951232
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 281405, 31, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (134, 191, 633)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1631)
[M::mem_pestat] mean and std.dev: (407.47, 435.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2149)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 234, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 694)
[M::mem_pestat] mean and std.dev: (259.21, 126.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 872)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (386, 612, 1780)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4568)
[M::mem_pestat] mean and std.dev: (1075.23, 1113.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5962)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 382, 1014)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2608)
[M::mem_pestat] mean and std.dev: (390.95, 300.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3405)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695192 sequences (100000159 bp) in 2.580 CPU sec, 3.167 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 280888, 25, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 356, 989)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2609)
[M::mem_pestat] mean and std.dev: (431.29, 418.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3419)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 240, 346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 712)
[M::mem_pestat] mean and std.dev: (264.53, 129.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 895)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (105, 595, 1226)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3468)
[M::mem_pestat] mean and std.dev: (810.54, 874.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4589)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 388, 550)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1222)
[M::mem_pestat] mean and std.dev: (399.54, 256.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1558)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697338 sequences (100000069 bp) in 2.001 CPU sec, 2.120 real sec...
[M::mem_process_seqs] Processed 697248 reads in 205.274 CPU sec, 6.704 real sec
sorting block 104, #reads = 1068428 mem = 536878054 peak = 1065951232
[M::mem_process_seqs] Processed 695848 reads in 140.098 CPU sec, 4.790 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 280772, 34, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (259, 399, 663)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1471)
[M::mem_pestat] mean and std.dev: (415.78, 279.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1875)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 241, 349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 719)
[M::mem_pestat] mean and std.dev: (266.87, 130.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 904)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (475, 1117, 2487)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6511)
[M::mem_pestat] mean and std.dev: (1312.81, 1088.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8523)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (351, 445, 1339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3315)
[M::mem_pestat] mean and std.dev: (612.76, 657.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4303)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 105, #reads = 1069060 mem = 536882126 peak = 1065951232
[M::process] read 696780 sequences (100000188 bp) in 2.516 CPU sec, 3.322 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 281476, 27, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (136, 321, 893)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2407)
[M::mem_pestat] mean and std.dev: (418.18, 345.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3164)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 233, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 688)
[M::mem_pestat] mean and std.dev: (258.03, 125.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 864)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (352, 755, 1883)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4945)
[M::mem_pestat] mean and std.dev: (1287.67, 1271.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6476)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 434, 988)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2560)
[M::mem_pestat] mean and std.dev: (632.36, 607.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3346)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695890 sequences (100000034 bp) in 1.913 CPU sec, 1.939 real sec...
[M::mem_process_seqs] Processed 695192 reads in 212.139 CPU sec, 7.187 real sec
[M::mem_process_seqs] Processed 697338 reads in 145.011 CPU sec, 4.727 real sec
sorting block 106, #reads = 1067469 mem = 536878518 peak = 1065951232
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 281492, 31, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 508, 1152)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3074)
[M::mem_pestat] mean and std.dev: (639.79, 628.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4035)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 234, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 688)
[M::mem_pestat] mean and std.dev: (258.13, 125.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 864)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (431, 1036, 2437)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6449)
[M::mem_pestat] mean and std.dev: (1252.07, 1160.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8455)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 280, 886)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2274)
[M::mem_pestat] mean and std.dev: (473.02, 485.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2968)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696402 sequences (100000050 bp) in 2.485 CPU sec, 3.250 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 281238, 24, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 558, 992)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2602)
[M::mem_pestat] mean and std.dev: (682.78, 519.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3407)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 238, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 708)
[M::mem_pestat] mean and std.dev: (263.42, 128.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 890)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 832, 2275)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6393)
[M::mem_pestat] mean and std.dev: (1324.71, 1355.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8452)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 296, 2574)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7354)
[M::mem_pestat] mean and std.dev: (1197.15, 1362.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9744)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696710 sequences (100000005 bp) in 2.153 CPU sec, 2.210 real sec...
[M::mem_process_seqs] Processed 696780 reads in 209.711 CPU sec, 6.824 real sec
[M::mem_process_seqs] Processed 695890 reads in 143.247 CPU sec, 4.918 real sec
sorting block 107, #reads = 1067541 mem = 536879233 peak = 1065951232
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 281293, 18, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (253, 456, 881)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2137)
[M::mem_pestat] mean and std.dev: (577.63, 440.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2765)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 235, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 698)
[M::mem_pestat] mean and std.dev: (260.65, 127.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 877)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 397, 1835)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5161)
[M::mem_pestat] mean and std.dev: (703.69, 900.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6824)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 335, 815)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2051)
[M::mem_pestat] mean and std.dev: (479.68, 414.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2669)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696776 sequences (100000231 bp) in 2.465 CPU sec, 3.077 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 282274, 26, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 378, 1197)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3165)
[M::mem_pestat] mean and std.dev: (674.77, 646.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4149)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 234, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 692)
[M::mem_pestat] mean and std.dev: (259.38, 126.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 869)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (305, 740, 1243)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3119)
[M::mem_pestat] mean and std.dev: (782.22, 752.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4057)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 317, 607)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1459)
[M::mem_pestat] mean and std.dev: (319.82, 220.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1885)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696096 sequences (100000002 bp) in 1.851 CPU sec, 1.925 real sec...
[M::mem_process_seqs] Processed 696402 reads in 210.551 CPU sec, 7.162 real sec
[M::mem_process_seqs] Processed 696710 reads in 145.461 CPU sec, 4.757 real sec
sorting block 108, #reads = 1067003 mem = 536878899 peak = 1065951232
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 281537, 26, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 278, 1240)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3378)
[M::mem_pestat] mean and std.dev: (671.03, 810.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4447)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 234, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 692)
[M::mem_pestat] mean and std.dev: (259.03, 126.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 869)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (76, 911, 1657)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4819)
[M::mem_pestat] mean and std.dev: (1302.15, 1350.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6703)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (257, 451, 694)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1568)
[M::mem_pestat] mean and std.dev: (444.00, 299.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2005)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701954 sequences (100000220 bp) in 2.755 CPU sec, 3.254 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 280926, 46, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (145, 297, 1796)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5098)
[M::mem_pestat] mean and std.dev: (811.00, 977.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6749)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 237, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 705)
[M::mem_pestat] mean and std.dev: (262.45, 128.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 886)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (293, 1048, 4618)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13268)
[M::mem_pestat] mean and std.dev: (2395.87, 2713.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17593)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 244, 719)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1787)
[M::mem_pestat] mean and std.dev: (387.62, 339.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2321)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705702 sequences (100000129 bp) in 2.171 CPU sec, 2.191 real sec...
[M::mem_process_seqs] Processed 696776 reads in 210.327 CPU sec, 6.810 real sec
sorting block 109, #reads = 1069255 mem = 536884099 peak = 1065951232
[M::mem_process_seqs] Processed 696096 reads in 147.439 CPU sec, 5.005 real sec
sorting block 110, #reads = 1066643 mem = 536880185 peak = 1065951232
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 283146, 12, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 243, 383)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 777)
[M::mem_pestat] mean and std.dev: (250.88, 107.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 974)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 222, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 666)
[M::mem_pestat] mean and std.dev: (248.22, 122.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 837)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (314, 1020, 1549)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4019)
[M::mem_pestat] mean and std.dev: (669.70, 558.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5254)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (268, 423, 678)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1498)
[M::mem_pestat] mean and std.dev: (475.74, 338.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1908)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704406 sequences (100000232 bp) in 2.805 CPU sec, 3.186 real sec...
[M::process] read 703070 sequences (100000143 bp) in 2.028 CPU sec, 2.034 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 284106, 15, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (120, 246, 536)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1368)
[M::mem_pestat] mean and std.dev: (333.97, 314.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1784)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 214, 311)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 637)
[M::mem_pestat] mean and std.dev: (239.33, 117.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 800)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (918, 1042, 2074)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4386)
[M::mem_pestat] mean and std.dev: (1169.38, 691.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5542)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 315, 1624)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4538)
[M::mem_pestat] mean and std.dev: (878.92, 1129.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5995)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701954 reads in 244.136 CPU sec, 8.169 real sec
[M::mem_process_seqs] Processed 705702 reads in 164.776 CPU sec, 5.331 real sec
sorting block 111, #reads = 1065511 mem = 536886239 peak = 1065951232
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 284549, 17, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 404, 980)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2522)
[M::mem_pestat] mean and std.dev: (640.07, 578.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3293)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 217, 318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 654)
[M::mem_pestat] mean and std.dev: (243.82, 120.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 822)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (276, 641, 1745)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4683)
[M::mem_pestat] mean and std.dev: (977.59, 957.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6152)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (231, 345, 461)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 921)
[M::mem_pestat] mean and std.dev: (307.06, 137.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1151)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702874 sequences (100000000 bp) in 2.748 CPU sec, 3.182 real sec...
[M::process] read 702020 sequences (100000277 bp) in 2.112 CPU sec, 2.304 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 283643, 41, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 185, 253)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (28, 403)
[M::mem_pestat] mean and std.dev: (191.96, 61.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 478)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 220, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 659)
[M::mem_pestat] mean and std.dev: (245.95, 120.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 828)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (269, 1215, 2397)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6653)
[M::mem_pestat] mean and std.dev: (1382.93, 1375.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8781)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 484, 855)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2143)
[M::mem_pestat] mean and std.dev: (574.63, 384.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2787)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704406 reads in 243.307 CPU sec, 7.912 real sec
sorting block 112, #reads = 1062594 mem = 536881876 peak = 1065951232
[M::mem_process_seqs] Processed 703070 reads in 174.661 CPU sec, 5.679 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 284410, 27, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 368, 1030)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2628)
[M::mem_pestat] mean and std.dev: (549.46, 413.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3427)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 220, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 659)
[M::mem_pestat] mean and std.dev: (245.84, 120.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 828)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 582, 1061)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2775)
[M::mem_pestat] mean and std.dev: (544.58, 491.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3632)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 439, 857)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2159)
[M::mem_pestat] mean and std.dev: (555.30, 420.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2810)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701856 sequences (100000098 bp) in 2.732 CPU sec, 3.172 real sec...
[M::process] read 701504 sequences (100000293 bp) in 1.907 CPU sec, 1.930 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 284216, 36, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 436, 604)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1492)
[M::mem_pestat] mean and std.dev: (438.47, 329.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1936)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 223, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 666)
[M::mem_pestat] mean and std.dev: (247.80, 120.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 837)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (976, 1590, 6657)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 18019)
[M::mem_pestat] mean and std.dev: (2763.58, 2700.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 23700)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 249, 651)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1503)
[M::mem_pestat] mean and std.dev: (372.54, 290.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1929)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702874 reads in 228.048 CPU sec, 7.347 real sec
sorting block 113, #reads = 1063054 mem = 536880283 peak = 1065951232
[M::mem_process_seqs] Processed 702020 reads in 154.676 CPU sec, 4.970 real sec
sorting block 114, #reads = 1066511 mem = 536879066 peak = 1068335104
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 283798, 36, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 301, 1040)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2784)
[M::mem_pestat] mean and std.dev: (669.62, 673.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3656)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 223, 323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 663)
[M::mem_pestat] mean and std.dev: (247.38, 120.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 833)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 676, 1694)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4762)
[M::mem_pestat] mean and std.dev: (763.06, 753.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6296)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (271, 421, 1482)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3904)
[M::mem_pestat] mean and std.dev: (848.88, 843.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5115)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699192 sequences (100000006 bp) in 2.921 CPU sec, 3.508 real sec...
[M::process] read 700790 sequences (100000168 bp) in 2.047 CPU sec, 2.083 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 284377, 20, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 299, 2287)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6467)
[M::mem_pestat] mean and std.dev: (656.18, 861.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8557)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 223, 323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 661)
[M::mem_pestat] mean and std.dev: (247.85, 120.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 830)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (268, 492, 925)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2239)
[M::mem_pestat] mean and std.dev: (577.39, 525.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2896)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 295, 549)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1235)
[M::mem_pestat] mean and std.dev: (397.10, 295.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1579)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701856 reads in 226.857 CPU sec, 7.402 real sec
[M::mem_process_seqs] Processed 701504 reads in 158.032 CPU sec, 5.128 real sec
sorting block 115, #reads = 1067396 mem = 536881965 peak = 1068335104
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 283330, 23, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 645, 1658)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4670)
[M::mem_pestat] mean and std.dev: (1060.21, 1118.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6176)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 230, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 691)
[M::mem_pestat] mean and std.dev: (255.85, 125.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 869)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (309, 598, 1910)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5112)
[M::mem_pestat] mean and std.dev: (1074.87, 1220.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6713)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 346, 1048)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2688)
[M::mem_pestat] mean and std.dev: (598.48, 571.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3508)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700886 sequences (100000060 bp) in 2.550 CPU sec, 3.135 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 283431, 24, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (279, 695, 1211)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3075)
[M::mem_pestat] mean and std.dev: (724.47, 657.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4007)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 225, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 668)
[M::mem_pestat] mean and std.dev: (250.22, 122.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 839)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (306, 1015, 1650)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4338)
[M::mem_pestat] mean and std.dev: (939.35, 717.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5682)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (312, 673, 1760)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4656)
[M::mem_pestat] mean and std.dev: (949.16, 1012.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6104)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701306 sequences (100000014 bp) in 1.943 CPU sec, 2.022 real sec...
[M::mem_process_seqs] Processed 699192 reads in 215.800 CPU sec, 7.031 real sec
sorting block 116, #reads = 1066756 mem = 536880917 peak = 1068335104
[M::mem_process_seqs] Processed 700790 reads in 153.833 CPU sec, 4.986 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 283799, 21, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 772, 1360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3718)
[M::mem_pestat] mean and std.dev: (843.38, 719.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4897)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 224, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 664)
[M::mem_pestat] mean and std.dev: (248.67, 120.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 834)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (68, 998, 1991)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5837)
[M::mem_pestat] mean and std.dev: (1225.95, 1216.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7760)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 241, 507)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1179)
[M::mem_pestat] mean and std.dev: (263.41, 153.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1515)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701002 sequences (100000014 bp) in 2.647 CPU sec, 3.337 real sec...
[M::process] read 700258 sequences (100000152 bp) in 2.036 CPU sec, 2.068 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 283869, 23, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 404, 1847)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5215)
[M::mem_pestat] mean and std.dev: (797.58, 868.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6899)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 223, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 664)
[M::mem_pestat] mean and std.dev: (248.32, 121.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 834)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (353, 503, 1219)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2951)
[M::mem_pestat] mean and std.dev: (803.90, 795.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3986)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 421, 790)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1938)
[M::mem_pestat] mean and std.dev: (507.18, 432.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2512)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700886 reads in 213.867 CPU sec, 6.967 real sec
sorting block 117, #reads = 1069657 mem = 536879084 peak = 1068335104
[M::mem_process_seqs] Processed 701306 reads in 144.906 CPU sec, 4.900 real sec
sorting block 118, #reads = 1069755 mem = 536879307 peak = 1068335104
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 283486, 23, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (244, 478, 907)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2233)
[M::mem_pestat] mean and std.dev: (550.35, 487.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2896)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 223, 323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 661)
[M::mem_pestat] mean and std.dev: (248.26, 120.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 830)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (270, 398, 1793)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4839)
[M::mem_pestat] mean and std.dev: (1093.04, 1226.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6362)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (237, 382, 695)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1611)
[M::mem_pestat] mean and std.dev: (417.88, 229.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2069)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698450 sequences (100000141 bp) in 2.712 CPU sec, 3.082 real sec...
[M::process] read 696968 sequences (100000191 bp) in 1.941 CPU sec, 1.946 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 282837, 27, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (141, 212, 935)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2523)
[M::mem_pestat] mean and std.dev: (595.24, 724.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3493)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 227, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 675)
[M::mem_pestat] mean and std.dev: (252.04, 123.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 848)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (50, 249, 710)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2030)
[M::mem_pestat] mean and std.dev: (362.48, 455.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2690)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (359, 770, 1903)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4991)
[M::mem_pestat] mean and std.dev: (1175.70, 1070.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6535)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701002 reads in 227.685 CPU sec, 7.588 real sec
[M::mem_process_seqs] Processed 700258 reads in 153.392 CPU sec, 4.919 real sec
sorting block 119, #reads = 1068908 mem = 536878582 peak = 1068335104
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 282143, 43, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (239, 358, 671)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1535)
[M::mem_pestat] mean and std.dev: (502.70, 379.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2022)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 232, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 698)
[M::mem_pestat] mean and std.dev: (258.22, 127.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 878)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (449, 645, 1323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3071)
[M::mem_pestat] mean and std.dev: (833.16, 590.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3945)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 415, 1086)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2866)
[M::mem_pestat] mean and std.dev: (553.63, 511.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3756)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699046 sequences (100000233 bp) in 2.530 CPU sec, 3.054 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 282095, 19, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 280, 1162)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3098)
[M::mem_pestat] mean and std.dev: (666.33, 668.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4066)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 237, 347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 719)
[M::mem_pestat] mean and std.dev: (263.92, 130.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 905)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 319, 1522)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4208)
[M::mem_pestat] mean and std.dev: (703.89, 762.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5551)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 385, 1527)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4187)
[M::mem_pestat] mean and std.dev: (668.86, 783.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5517)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698484 sequences (100000160 bp) in 2.145 CPU sec, 2.186 real sec...
[M::mem_process_seqs] Processed 698450 reads in 215.850 CPU sec, 7.112 real sec
[M::mem_process_seqs] Processed 696968 reads in 145.789 CPU sec, 4.733 real sec
sorting block 120, #reads = 1068072 mem = 536884348 peak = 1068335104
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 282590, 25, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 520, 1354)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3626)
[M::mem_pestat] mean and std.dev: (697.41, 667.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4762)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 230, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 688)
[M::mem_pestat] mean and std.dev: (255.35, 125.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 865)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (80, 372, 961)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2723)
[M::mem_pestat] mean and std.dev: (503.29, 546.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3604)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 474, 906)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2384)
[M::mem_pestat] mean and std.dev: (557.80, 463.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3123)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697870 sequences (100000263 bp) in 2.710 CPU sec, 3.082 real sec...
[M::process] read 697542 sequences (100000009 bp) in 2.064 CPU sec, 2.077 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 282474, 23, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 214, 733)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1873)
[M::mem_pestat] mean and std.dev: (315.06, 274.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2443)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 232, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 695)
[M::mem_pestat] mean and std.dev: (257.36, 126.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 874)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 847, 1385)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3769)
[M::mem_pestat] mean and std.dev: (837.50, 833.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4961)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 303, 987)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2509)
[M::mem_pestat] mean and std.dev: (541.45, 519.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3270)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699046 reads in 210.664 CPU sec, 6.785 real sec
sorting block 121, #reads = 1068712 mem = 536877872 peak = 1068335104
[M::mem_process_seqs] Processed 698484 reads in 145.079 CPU sec, 4.663 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 282307, 42, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 323, 1185)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3107)
[M::mem_pestat] mean and std.dev: (695.40, 776.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4068)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 233, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 702)
[M::mem_pestat] mean and std.dev: (259.20, 127.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 883)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 638, 1385)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3763)
[M::mem_pestat] mean and std.dev: (795.61, 761.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4952)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (239, 459, 785)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1877)
[M::mem_pestat] mean and std.dev: (486.26, 338.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2423)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 122, #reads = 1068584 mem = 536886115 peak = 1068335104
[M::process] read 697232 sequences (100000118 bp) in 2.648 CPU sec, 3.173 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 282132, 24, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (246, 382, 1241)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3231)
[M::mem_pestat] mean and std.dev: (705.58, 595.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4226)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 233, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 693)
[M::mem_pestat] mean and std.dev: (258.39, 126.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 871)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (279, 1025, 2522)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7008)
[M::mem_pestat] mean and std.dev: (1254.00, 1317.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9251)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 298, 778)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1926)
[M::mem_pestat] mean and std.dev: (486.58, 414.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2500)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696802 sequences (100000180 bp) in 2.136 CPU sec, 2.225 real sec...
[M::mem_process_seqs] Processed 697870 reads in 213.368 CPU sec, 6.915 real sec
[M::mem_process_seqs] Processed 697542 reads in 150.266 CPU sec, 4.818 real sec
sorting block 123, #reads = 1067356 mem = 536884298 peak = 1068335104
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 281986, 29, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 375, 676)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1684)
[M::mem_pestat] mean and std.dev: (440.97, 330.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2188)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 234, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 700)
[M::mem_pestat] mean and std.dev: (260.14, 127.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 880)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 581, 1057)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2817)
[M::mem_pestat] mean and std.dev: (755.70, 809.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3994)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 292, 861)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2233)
[M::mem_pestat] mean and std.dev: (398.82, 320.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2919)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695080 sequences (100000184 bp) in 2.962 CPU sec, 3.375 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 281995, 23, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 299, 1457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4005)
[M::mem_pestat] mean and std.dev: (779.43, 999.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5279)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 236, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 701)
[M::mem_pestat] mean and std.dev: (260.95, 127.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 881)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 627, 1343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3735)
[M::mem_pestat] mean and std.dev: (876.14, 861.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4931)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 347, 1024)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2638)
[M::mem_pestat] mean and std.dev: (564.22, 622.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3445)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696846 sequences (100000188 bp) in 1.815 CPU sec, 1.825 real sec...
[M::mem_process_seqs] Processed 697232 reads in 211.875 CPU sec, 6.870 real sec
[M::mem_process_seqs] Processed 696802 reads in 144.688 CPU sec, 4.742 real sec
sorting block 124, #reads = 1068126 mem = 536878733 peak = 1068335104
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 281216, 25, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 338, 904)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2318)
[M::mem_pestat] mean and std.dev: (446.88, 432.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3025)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 242, 352)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 728)
[M::mem_pestat] mean and std.dev: (268.15, 131.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 916)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (144, 666, 1544)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4344)
[M::mem_pestat] mean and std.dev: (680.50, 631.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5744)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 368, 1037)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2677)
[M::mem_pestat] mean and std.dev: (537.97, 505.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3497)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697748 sequences (100000176 bp) in 2.925 CPU sec, 3.233 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 281581, 39, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 238, 583)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1375)
[M::mem_pestat] mean and std.dev: (318.52, 212.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1771)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 235, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 701)
[M::mem_pestat] mean and std.dev: (260.81, 128.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 881)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 603, 3097)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8919)
[M::mem_pestat] mean and std.dev: (2019.97, 2397.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11830)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (271, 826, 1784)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4810)
[M::mem_pestat] mean and std.dev: (972.23, 803.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6323)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696814 sequences (100000114 bp) in 1.986 CPU sec, 1.998 real sec...
[M::mem_process_seqs] Processed 695080 reads in 211.776 CPU sec, 6.868 real sec
sorting block 125, #reads = 1069872 mem = 536880308 peak = 1068335104
[M::mem_process_seqs] Processed 696846 reads in 145.402 CPU sec, 4.647 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 281845, 21, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 321, 845)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2099)
[M::mem_pestat] mean and std.dev: (459.72, 399.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2726)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 232, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 690)
[M::mem_pestat] mean and std.dev: (257.49, 125.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 867)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (312, 1083, 1959)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5253)
[M::mem_pestat] mean and std.dev: (1415.38, 1366.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6900)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (241, 311, 783)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1867)
[M::mem_pestat] mean and std.dev: (413.69, 301.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2409)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 126, #reads = 1069762 mem = 536881668 peak = 1068335104
[M::process] read 697028 sequences (100000146 bp) in 3.784 CPU sec, 4.007 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 281774, 27, 24)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 392, 1458)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3998)
[M::mem_pestat] mean and std.dev: (655.05, 750.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5268)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 234, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 700)
[M::mem_pestat] mean and std.dev: (259.90, 127.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 880)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (597, 1099, 2431)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6099)
[M::mem_pestat] mean and std.dev: (1297.38, 948.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7933)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 318, 850)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2212)
[M::mem_pestat] mean and std.dev: (407.32, 297.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2893)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697748 reads in 198.996 CPU sec, 6.330 real sec
[M::mem_process_seqs] Processed 696814 reads in 133.574 CPU sec, 4.218 real sec
[M::process] read 697916 sequences (100000034 bp) in 2.612 CPU sec, 2.675 real sec...
sorting block 127, #reads = 1069283 mem = 536884341 peak = 1068335104
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 281834, 31, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (316, 484, 790)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1738)
[M::mem_pestat] mean and std.dev: (560.95, 352.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2212)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 234, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 697)
[M::mem_pestat] mean and std.dev: (259.57, 127.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 876)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (312, 462, 1213)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3015)
[M::mem_pestat] mean and std.dev: (755.97, 787.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3916)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 348, 1182)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3164)
[M::mem_pestat] mean and std.dev: (529.11, 543.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4155)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697596 sequences (100000209 bp) in 3.154 CPU sec, 3.358 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 281589, 17, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (229, 321, 384)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 694)
[M::mem_pestat] mean and std.dev: (272.35, 99.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 849)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 231, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 687)
[M::mem_pestat] mean and std.dev: (257.25, 126.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 863)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 505, 1488)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4152)
[M::mem_pestat] mean and std.dev: (665.80, 692.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5484)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 330, 1290)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3416)
[M::mem_pestat] mean and std.dev: (589.42, 592.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4479)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698064 sequences (100000197 bp) in 2.059 CPU sec, 2.067 real sec...
[M::mem_process_seqs] Processed 697028 reads in 212.185 CPU sec, 6.803 real sec
sorting block 128, #reads = 1068673 mem = 536880541 peak = 1068335104
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 281729, 26, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 228, 1863)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5255)
[M::mem_pestat] mean and std.dev: (982.14, 1308.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6951)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 232, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 693)
[M::mem_pestat] mean and std.dev: (258.35, 127.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 871)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (262, 872, 1342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3502)
[M::mem_pestat] mean and std.dev: (875.76, 771.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4582)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 372, 470)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 968)
[M::mem_pestat] mean and std.dev: (296.73, 132.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1217)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701798 sequences (100000104 bp) in 2.754 CPU sec, 2.762 real sec...
[M::mem_process_seqs] Processed 697596 reads in 126.514 CPU sec, 4.020 real sec
[M::mem_process_seqs] Processed 697916 reads in 309.345 CPU sec, 9.905 real sec
sorting block 129, #reads = 1066854 mem = 536878507 peak = 1068335104
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 281454, 22, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 371, 1041)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2701)
[M::mem_pestat] mean and std.dev: (491.59, 370.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3531)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 231, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 686)
[M::mem_pestat] mean and std.dev: (256.72, 126.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 862)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 806, 1209)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3219)
[M::mem_pestat] mean and std.dev: (757.10, 660.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4224)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (237, 356, 667)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1527)
[M::mem_pestat] mean and std.dev: (402.10, 298.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1957)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702220 sequences (100000078 bp) in 3.125 CPU sec, 3.478 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 282537, 26, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 469, 1256)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3346)
[M::mem_pestat] mean and std.dev: (718.00, 729.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4391)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 221, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 657)
[M::mem_pestat] mean and std.dev: (246.85, 121.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 825)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (311, 910, 2103)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5687)
[M::mem_pestat] mean and std.dev: (1081.92, 993.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7479)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 274, 844)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2130)
[M::mem_pestat] mean and std.dev: (385.63, 346.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2773)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701596 sequences (100000049 bp) in 1.953 CPU sec, 2.019 real sec...
[M::mem_process_seqs] Processed 698064 reads in 273.917 CPU sec, 8.795 real sec
[M::mem_process_seqs] Processed 701798 reads in 178.089 CPU sec, 5.722 real sec
sorting block 130, #reads = 1065185 mem = 536879661 peak = 1068335104
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 283862, 21, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (135, 166, 551)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1383)
[M::mem_pestat] mean and std.dev: (267.10, 196.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1799)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 223, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 666)
[M::mem_pestat] mean and std.dev: (248.01, 121.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 837)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (380, 401, 883)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1889)
[M::mem_pestat] mean and std.dev: (513.42, 384.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2392)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 640, 2781)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7895)
[M::mem_pestat] mean and std.dev: (1107.80, 1047.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10452)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701044 sequences (100000104 bp) in 2.959 CPU sec, 3.261 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 283892, 12, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 643, 1448)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3910)
[M::mem_pestat] mean and std.dev: (833.89, 723.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5141)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 224, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 672)
[M::mem_pestat] mean and std.dev: (250.04, 123.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 845)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (754, 1222, 1905)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4207)
[M::mem_pestat] mean and std.dev: (1055.27, 731.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5358)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 248, 737)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1837)
[M::mem_pestat] mean and std.dev: (373.74, 332.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2387)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699914 sequences (100000170 bp) in 2.165 CPU sec, 2.246 real sec...
[M::mem_process_seqs] Processed 702220 reads in 210.253 CPU sec, 6.720 real sec
sorting block 131, #reads = 1060381 mem = 536879784 peak = 1068335104
[M::mem_process_seqs] Processed 701596 reads in 142.404 CPU sec, 4.550 real sec
sorting block 132, #reads = 1073080 mem = 536878558 peak = 1075662848
[M::process] read 700270 sequences (100000125 bp) in 2.880 CPU sec, 3.332 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 283071, 32, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (252, 758, 1956)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5364)
[M::mem_pestat] mean and std.dev: (742.27, 816.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7068)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 228, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 681)
[M::mem_pestat] mean and std.dev: (252.88, 123.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 856)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (145, 444, 613)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1549)
[M::mem_pestat] mean and std.dev: (404.28, 355.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2017)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 432, 827)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2061)
[M::mem_pestat] mean and std.dev: (504.10, 347.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2678)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700056 sequences (100000239 bp) in 1.880 CPU sec, 1.921 real sec...
[M::mem_process_seqs] Processed 699914 reads in 116.310 CPU sec, 3.729 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 284112, 30, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (238, 556, 2513)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7063)
[M::mem_pestat] mean and std.dev: (1095.82, 1063.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9338)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 226, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 677)
[M::mem_pestat] mean and std.dev: (251.45, 123.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 851)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (313, 695, 1451)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3727)
[M::mem_pestat] mean and std.dev: (1045.90, 1138.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5600)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 310, 734)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1758)
[M::mem_pestat] mean and std.dev: (415.65, 246.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2270)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 283716, 15, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 467, 2496)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7164)
[M::mem_pestat] mean and std.dev: (1040.92, 1138.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9498)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 228, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 687)
[M::mem_pestat] mean and std.dev: (254.19, 125.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 864)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (393, 1305, 1309)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3141)
[M::mem_pestat] mean and std.dev: (1016.29, 731.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4057)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (256, 362, 893)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2167)
[M::mem_pestat] mean and std.dev: (505.38, 380.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2804)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701044 reads in 314.304 CPU sec, 10.123 real sec
[M::process] read 696476 sequences (100000088 bp) in 2.039 CPU sec, 2.046 real sec...
sorting block 133, #reads = 1073848 mem = 536879580 peak = 1075662848
[M::mem_process_seqs] Processed 700270 reads in 162.874 CPU sec, 5.248 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 283190, 25, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 360, 1373)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3745)
[M::mem_pestat] mean and std.dev: (753.64, 850.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4931)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 229, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 690)
[M::mem_pestat] mean and std.dev: (255.05, 125.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 868)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 588, 2076)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5808)
[M::mem_pestat] mean and std.dev: (1073.28, 1154.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7674)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 249, 754)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1844)
[M::mem_pestat] mean and std.dev: (271.00, 125.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2389)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697808 sequences (100000102 bp) in 2.725 CPU sec, 3.269 real sec...
sorting block 134, #reads = 1074126 mem = 536883820 peak = 1075662848
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 282606, 25, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 266, 1011)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2655)
[M::mem_pestat] mean and std.dev: (598.36, 644.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3477)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 241, 348)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 720)
[M::mem_pestat] mean and std.dev: (264.86, 129.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 906)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 848, 987)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2561)
[M::mem_pestat] mean and std.dev: (658.52, 526.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3348)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (268, 479, 2399)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6661)
[M::mem_pestat] mean and std.dev: (1423.39, 1870.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8904)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700482 sequences (100000084 bp) in 1.859 CPU sec, 1.868 real sec...
[M::mem_process_seqs] Processed 700056 reads in 198.446 CPU sec, 6.414 real sec
[M::mem_process_seqs] Processed 696476 reads in 136.295 CPU sec, 4.350 real sec
sorting block 135, #reads = 1073967 mem = 536881934 peak = 1075662848
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 283223, 32, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 287, 763)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1943)
[M::mem_pestat] mean and std.dev: (314.45, 232.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2533)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 236, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 711)
[M::mem_pestat] mean and std.dev: (261.13, 128.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 895)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (761, 1229, 1465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2873)
[M::mem_pestat] mean and std.dev: (1155.62, 480.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3577)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 356, 575)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1277)
[M::mem_pestat] mean and std.dev: (418.71, 293.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1628)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700114 sequences (100000129 bp) in 2.377 CPU sec, 2.577 real sec...
[M::process] read 700694 sequences (100000245 bp) in 2.234 CPU sec, 2.274 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 283290, 32, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 350, 1603)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4375)
[M::mem_pestat] mean and std.dev: (850.39, 839.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5761)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 226, 327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 671)
[M::mem_pestat] mean and std.dev: (250.73, 122.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 843)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (610, 1097, 2542)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6406)
[M::mem_pestat] mean and std.dev: (1197.90, 845.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8338)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 289, 872)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2250)
[M::mem_pestat] mean and std.dev: (489.88, 402.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2939)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697808 reads in 201.206 CPU sec, 6.447 real sec
[M::mem_process_seqs] Processed 700482 reads in 135.910 CPU sec, 4.344 real sec
sorting block 136, #reads = 1072537 mem = 536880651 peak = 1075662848
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 283197, 23, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 249, 900)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2384)
[M::mem_pestat] mean and std.dev: (512.21, 499.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3126)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 227, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 672)
[M::mem_pestat] mean and std.dev: (251.05, 121.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 844)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (335, 478, 1227)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3011)
[M::mem_pestat] mean and std.dev: (724.22, 656.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3903)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (243, 374, 664)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1506)
[M::mem_pestat] mean and std.dev: (409.31, 284.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1927)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700288 sequences (100000157 bp) in 2.654 CPU sec, 2.986 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 283738, 40, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 425, 637)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1533)
[M::mem_pestat] mean and std.dev: (448.68, 313.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1981)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 225, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 665)
[M::mem_pestat] mean and std.dev: (249.41, 120.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 835)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 782, 2356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6770)
[M::mem_pestat] mean and std.dev: (1451.42, 1754.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8977)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (293, 411, 1457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3785)
[M::mem_pestat] mean and std.dev: (699.59, 710.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4949)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699742 sequences (100000230 bp) in 2.082 CPU sec, 2.085 real sec...
[M::mem_process_seqs] Processed 700114 reads in 213.305 CPU sec, 6.925 real sec
sorting block 137, #reads = 1073814 mem = 536875545 peak = 1075662848
[M::mem_process_seqs] Processed 700694 reads in 142.514 CPU sec, 4.625 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 283304, 28, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 367, 1065)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2829)
[M::mem_pestat] mean and std.dev: (627.34, 606.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3711)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 226, 327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 671)
[M::mem_pestat] mean and std.dev: (250.39, 121.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 843)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (395, 687, 3223)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8879)
[M::mem_pestat] mean and std.dev: (1502.50, 1594.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11707)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (274, 444, 1028)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2536)
[M::mem_pestat] mean and std.dev: (549.55, 417.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3290)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699446 sequences (100000058 bp) in 2.281 CPU sec, 2.460 real sec...
sorting block 138, #reads = 1070973 mem = 536878558 peak = 1075662848
[M::process] read 699316 sequences (100000167 bp) in 1.962 CPU sec, 1.965 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 282766, 41, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 285, 924)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2448)
[M::mem_pestat] mean and std.dev: (545.41, 539.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3210)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 228, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 678)
[M::mem_pestat] mean and std.dev: (252.67, 122.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 852)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (297, 559, 2269)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6213)
[M::mem_pestat] mean and std.dev: (1536.76, 1746.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8522)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 264, 612)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1478)
[M::mem_pestat] mean and std.dev: (272.30, 170.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1911)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700288 reads in 195.816 CPU sec, 6.315 real sec
[M::mem_process_seqs] Processed 699742 reads in 130.077 CPU sec, 4.136 real sec
sorting block 139, #reads = 1072204 mem = 536878252 peak = 1075662848
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 283427, 30, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 384, 949)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2453)
[M::mem_pestat] mean and std.dev: (528.63, 488.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3205)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 229, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 679)
[M::mem_pestat] mean and std.dev: (253.52, 123.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 853)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (530, 898, 1386)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3098)
[M::mem_pestat] mean and std.dev: (763.04, 480.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3954)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 421, 1027)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2645)
[M::mem_pestat] mean and std.dev: (516.74, 493.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3454)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698310 sequences (100000190 bp) in 2.260 CPU sec, 2.384 real sec...
[M::process] read 696938 sequences (100000186 bp) in 1.870 CPU sec, 1.877 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 282938, 26, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (229, 322, 967)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2443)
[M::mem_pestat] mean and std.dev: (497.91, 410.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3181)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 230, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 685)
[M::mem_pestat] mean and std.dev: (254.89, 124.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 861)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (132, 630, 1167)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3237)
[M::mem_pestat] mean and std.dev: (692.00, 666.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4272)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 522, 2133)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5951)
[M::mem_pestat] mean and std.dev: (1312.52, 1563.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7860)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699446 reads in 179.249 CPU sec, 5.719 real sec
[M::mem_process_seqs] Processed 699316 reads in 117.741 CPU sec, 3.822 real sec
sorting block 140, #reads = 1072889 mem = 536879629 peak = 1075662848
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 283466, 33, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 295, 761)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1941)
[M::mem_pestat] mean and std.dev: (413.84, 422.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2531)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 232, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 695)
[M::mem_pestat] mean and std.dev: (257.81, 126.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 874)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (122, 679, 1271)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3569)
[M::mem_pestat] mean and std.dev: (724.81, 633.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4718)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 343, 925)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2385)
[M::mem_pestat] mean and std.dev: (568.33, 511.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3115)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698374 sequences (100000298 bp) in 2.263 CPU sec, 2.372 real sec...
[M::process] read 698822 sequences (100000072 bp) in 1.440 CPU sec, 1.441 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 282267, 35, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 827, 1123)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2997)
[M::mem_pestat] mean and std.dev: (707.85, 555.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3934)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 237, 346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 716)
[M::mem_pestat] mean and std.dev: (263.13, 129.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 901)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (420, 1146, 2539)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6777)
[M::mem_pestat] mean and std.dev: (1517.33, 1733.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8896)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 386, 1732)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4754)
[M::mem_pestat] mean and std.dev: (895.59, 1046.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6265)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698310 reads in 179.038 CPU sec, 5.784 real sec
[M::mem_process_seqs] Processed 696938 reads in 120.496 CPU sec, 3.846 real sec
sorting block 141, #reads = 1073477 mem = 536879638 peak = 1075662848
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 282568, 31, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (230, 393, 895)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2225)
[M::mem_pestat] mean and std.dev: (502.18, 398.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2890)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 232, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 690)
[M::mem_pestat] mean and std.dev: (256.94, 125.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 867)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 515, 1394)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3822)
[M::mem_pestat] mean and std.dev: (568.00, 550.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5036)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 313, 1201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3149)
[M::mem_pestat] mean and std.dev: (645.21, 619.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4123)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699128 sequences (100000257 bp) in 2.790 CPU sec, 2.927 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 282830, 24, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (720, 885, 1687)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3621)
[M::mem_pestat] mean and std.dev: (949.50, 625.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4588)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 231, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 685)
[M::mem_pestat] mean and std.dev: (254.96, 123.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 861)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (299, 1024, 1934)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5204)
[M::mem_pestat] mean and std.dev: (919.50, 735.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6839)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 456, 1306)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3478)
[M::mem_pestat] mean and std.dev: (716.20, 695.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4564)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699060 sequences (100000222 bp) in 1.960 CPU sec, 1.962 real sec...
[M::mem_process_seqs] Processed 698374 reads in 191.387 CPU sec, 6.111 real sec
sorting block 142, #reads = 1072145 mem = 536878878 peak = 1075662848
[M::mem_process_seqs] Processed 698822 reads in 126.000 CPU sec, 3.999 real sec
sorting block 143, #reads = 1072810 mem = 536880593 peak = 1075662848
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 283257, 33, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (133, 259, 887)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2395)
[M::mem_pestat] mean and std.dev: (414.50, 345.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3149)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 231, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 685)
[M::mem_pestat] mean and std.dev: (255.11, 124.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 861)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (396, 910, 1238)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2922)
[M::mem_pestat] mean and std.dev: (757.10, 562.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3764)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 424, 1108)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2884)
[M::mem_pestat] mean and std.dev: (668.11, 714.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3772)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698144 sequences (100000255 bp) in 2.308 CPU sec, 2.420 real sec...
[M::process] read 698252 sequences (100000030 bp) in 1.910 CPU sec, 1.902 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 283011, 27, 22)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 282, 901)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2271)
[M::mem_pestat] mean and std.dev: (487.28, 424.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2956)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 231, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 685)
[M::mem_pestat] mean and std.dev: (255.11, 124.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 861)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (255, 664, 2137)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5901)
[M::mem_pestat] mean and std.dev: (1117.52, 1142.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7783)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (286, 366, 993)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2407)
[M::mem_pestat] mean and std.dev: (567.29, 395.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3114)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699128 reads in 177.817 CPU sec, 5.653 real sec
[M::mem_process_seqs] Processed 699060 reads in 121.278 CPU sec, 3.859 real sec
sorting block 144, #reads = 1071938 mem = 536879035 peak = 1075662848
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 282121, 15, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (234, 863, 1602)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4338)
[M::mem_pestat] mean and std.dev: (1003.75, 932.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5706)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 232, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 689)
[M::mem_pestat] mean and std.dev: (256.61, 125.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 866)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (548, 794, 939)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1721)
[M::mem_pestat] mean and std.dev: (660.71, 437.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2409)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 361, 1049)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2713)
[M::mem_pestat] mean and std.dev: (613.33, 626.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3545)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698082 sequences (100000002 bp) in 2.662 CPU sec, 2.794 real sec...
[M::process] read 698416 sequences (100000244 bp) in 1.600 CPU sec, 1.594 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 282366, 31, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (320, 480, 1356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3428)
[M::mem_pestat] mean and std.dev: (669.17, 622.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4464)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 232, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 692)
[M::mem_pestat] mean and std.dev: (257.35, 126.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 870)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (359, 683, 927)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2063)
[M::mem_pestat] mean and std.dev: (587.33, 363.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2631)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 360, 1287)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3443)
[M::mem_pestat] mean and std.dev: (698.45, 707.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4521)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698144 reads in 187.986 CPU sec, 5.989 real sec
sorting block 145, #reads = 1071038 mem = 536880957 peak = 1075662848
[M::process] read 698854 sequences (100000101 bp) in 2.088 CPU sec, 2.098 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 282093, 35, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (245, 426, 1487)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3971)
[M::mem_pestat] mean and std.dev: (895.66, 967.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5213)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 232, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 695)
[M::mem_pestat] mean and std.dev: (257.72, 126.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 874)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (420, 714, 1657)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4131)
[M::mem_pestat] mean and std.dev: (1160.49, 1081.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5487)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (266, 381, 654)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1430)
[M::mem_pestat] mean and std.dev: (443.87, 263.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1818)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698082 reads in 106.984 CPU sec, 3.664 real sec
[M::mem_process_seqs] Processed 698252 reads in 265.833 CPU sec, 8.758 real sec
sorting block 146, #reads = 1069460 mem = 536879530 peak = 1075662848
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 282583, 28, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 437, 1006)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2608)
[M::mem_pestat] mean and std.dev: (588.26, 593.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3409)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 231, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 692)
[M::mem_pestat] mean and std.dev: (256.82, 126.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 870)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 292, 2452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6956)
[M::mem_pestat] mean and std.dev: (1165.93, 1685.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9208)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 363, 1018)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2652)
[M::mem_pestat] mean and std.dev: (497.60, 422.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3469)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698350 sequences (100000277 bp) in 2.699 CPU sec, 2.994 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 282050, 37, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 352, 1053)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2841)
[M::mem_pestat] mean and std.dev: (692.28, 801.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3900)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 230, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 686)
[M::mem_pestat] mean and std.dev: (255.87, 125.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 862)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (287, 622, 1200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3026)
[M::mem_pestat] mean and std.dev: (758.59, 585.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3939)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 339, 903)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2313)
[M::mem_pestat] mean and std.dev: (608.37, 530.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3018)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698022 sequences (100000235 bp) in 1.920 CPU sec, 1.921 real sec...
[M::mem_process_seqs] Processed 698416 reads in 226.105 CPU sec, 7.221 real sec
sorting block 147, #reads = 1069467 mem = 536880206 peak = 1075662848
[M::mem_process_seqs] Processed 698854 reads in 135.788 CPU sec, 4.305 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 281658, 31, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 533, 2009)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5591)
[M::mem_pestat] mean and std.dev: (806.83, 778.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7382)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 231, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 689)
[M::mem_pestat] mean and std.dev: (256.71, 126.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 866)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (256, 1082, 2387)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6649)
[M::mem_pestat] mean and std.dev: (1373.57, 1402.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8780)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 313, 840)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2156)
[M::mem_pestat] mean and std.dev: (427.74, 414.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2814)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698704 sequences (100000237 bp) in 2.698 CPU sec, 2.881 real sec...
[M::process] read 698556 sequences (100000278 bp) in 1.680 CPU sec, 1.672 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 281694, 32, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 651, 1586)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4322)
[M::mem_pestat] mean and std.dev: (875.83, 744.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5690)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 231, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 695)
[M::mem_pestat] mean and std.dev: (257.82, 127.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 874)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (353, 1090, 1307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3215)
[M::mem_pestat] mean and std.dev: (940.87, 745.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4169)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 389, 850)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2114)
[M::mem_pestat] mean and std.dev: (477.79, 385.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2746)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698350 reads in 204.993 CPU sec, 6.637 real sec
sorting block 148, #reads = 1068094 mem = 536879059 peak = 1075662848
[M::mem_process_seqs] Processed 698022 reads in 132.716 CPU sec, 4.241 real sec
sorting block 149, #reads = 1067364 mem = 536877954 peak = 1075662848
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 282080, 20, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 434, 1248)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3346)
[M::mem_pestat] mean and std.dev: (568.94, 687.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4395)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 228, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 676)
[M::mem_pestat] mean and std.dev: (253.80, 124.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 849)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (404, 1237, 1920)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4952)
[M::mem_pestat] mean and std.dev: (1334.30, 1212.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6468)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 379, 1485)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4031)
[M::mem_pestat] mean and std.dev: (746.67, 783.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5304)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698990 sequences (100000069 bp) in 2.717 CPU sec, 2.843 real sec...
[M::process] read 702152 sequences (100000007 bp) in 1.676 CPU sec, 1.681 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 282002, 20, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 594, 1505)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4147)
[M::mem_pestat] mean and std.dev: (866.76, 870.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5468)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 229, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 683)
[M::mem_pestat] mean and std.dev: (255.21, 125.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 858)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (505, 890, 1193)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2569)
[M::mem_pestat] mean and std.dev: (826.95, 438.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3257)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (256, 682, 1120)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2848)
[M::mem_pestat] mean and std.dev: (641.82, 511.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3712)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698704 reads in 206.206 CPU sec, 6.653 real sec
[M::mem_process_seqs] Processed 698556 reads in 139.020 CPU sec, 4.446 real sec
sorting block 150, #reads = 1067623 mem = 536876186 peak = 1075662848
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 281770, 27, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 315, 988)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2584)
[M::mem_pestat] mean and std.dev: (547.89, 604.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3382)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 227, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 663)
[M::mem_pestat] mean and std.dev: (250.73, 121.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 832)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (225, 816, 1723)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4719)
[M::mem_pestat] mean and std.dev: (1208.23, 1256.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6236)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 266, 677)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1657)
[M::mem_pestat] mean and std.dev: (437.35, 390.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2147)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706094 sequences (100000166 bp) in 2.839 CPU sec, 2.976 real sec...
[M::process] read 703332 sequences (100000062 bp) in 2.050 CPU sec, 2.049 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 282704, 32, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 303, 572)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1370)
[M::mem_pestat] mean and std.dev: (343.02, 256.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1769)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 221, 320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 654)
[M::mem_pestat] mean and std.dev: (245.94, 120.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 821)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 998, 1490)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4036)
[M::mem_pestat] mean and std.dev: (924.60, 855.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5309)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 375, 817)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2039)
[M::mem_pestat] mean and std.dev: (480.29, 461.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2650)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698990 reads in 228.166 CPU sec, 7.254 real sec
sorting block 151, #reads = 1064192 mem = 536880631 peak = 1075662848
[M::mem_process_seqs] Processed 702152 reads in 171.076 CPU sec, 5.468 real sec
[M::process] read 703166 sequences (100000104 bp) in 3.325 CPU sec, 3.443 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 284351, 29, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 361, 967)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2483)
[M::mem_pestat] mean and std.dev: (429.13, 398.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3241)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 214, 314)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 646)
[M::mem_pestat] mean and std.dev: (240.99, 119.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 812)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (357, 984, 2352)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6342)
[M::mem_pestat] mean and std.dev: (1319.34, 1190.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8337)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 430, 1579)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4327)
[M::mem_pestat] mean and std.dev: (759.38, 714.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5701)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704016 sequences (100000023 bp) in 1.990 CPU sec, 1.994 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 283731, 23, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (239, 428, 778)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1856)
[M::mem_pestat] mean and std.dev: (406.96, 250.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2395)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 219, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 664)
[M::mem_pestat] mean and std.dev: (246.24, 121.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 835)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (375, 855, 1019)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2307)
[M::mem_pestat] mean and std.dev: (680.25, 384.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2951)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 302, 719)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1699)
[M::mem_pestat] mean and std.dev: (396.30, 304.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2189)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 706094 reads in 222.651 CPU sec, 7.073 real sec
sorting block 152, #reads = 1057829 mem = 536884014 peak = 1075662848
[M::mem_process_seqs] Processed 703332 reads in 253.992 CPU sec, 8.102 real sec
sorting block 153, #reads = 1063480 mem = 536882660 peak = 1075662848
[M::process] read 703130 sequences (100000069 bp) in 2.521 CPU sec, 2.606 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 284235, 19, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 469, 1062)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2828)
[M::mem_pestat] mean and std.dev: (631.93, 587.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3711)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 219, 320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 658)
[M::mem_pestat] mean and std.dev: (245.44, 120.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 827)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 409, 1127)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2919)
[M::mem_pestat] mean and std.dev: (632.11, 621.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3815)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 347, 507)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1119)
[M::mem_pestat] mean and std.dev: (384.65, 233.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1425)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700698 sequences (100000190 bp) in 1.977 CPU sec, 1.981 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 284594, 22, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (234, 328, 1052)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2688)
[M::mem_pestat] mean and std.dev: (599.62, 569.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3506)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 217, 315)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 643)
[M::mem_pestat] mean and std.dev: (242.42, 117.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 807)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (451, 503, 1315)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3043)
[M::mem_pestat] mean and std.dev: (777.05, 552.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3907)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 337, 669)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1619)
[M::mem_pestat] mean and std.dev: (344.69, 291.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2094)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 283913, 27, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 357, 834)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2072)
[M::mem_pestat] mean and std.dev: (374.62, 275.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2691)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 220, 319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 653)
[M::mem_pestat] mean and std.dev: (244.55, 118.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 820)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (271, 888, 1507)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3979)
[M::mem_pestat] mean and std.dev: (1051.41, 922.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5215)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 225, 404)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 846)
[M::mem_pestat] mean and std.dev: (283.15, 151.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1067)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703166 reads in 299.023 CPU sec, 9.551 real sec
[M::mem_process_seqs] Processed 704016 reads in 228.153 CPU sec, 7.319 real sec
sorting block 154, #reads = 1062822 mem = 536878940 peak = 1075662848
[M::mem_process_seqs] Processed 703130 reads in 253.724 CPU sec, 8.143 real sec
[M::process] read 702348 sequences (100000006 bp) in 2.842 CPU sec, 3.002 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 283552, 18, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 278, 617)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1523)
[M::mem_pestat] mean and std.dev: (336.94, 258.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1976)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 230, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 702)
[M::mem_pestat] mean and std.dev: (256.56, 127.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 884)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (366, 929, 2023)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5337)
[M::mem_pestat] mean and std.dev: (1108.18, 1041.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6994)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (242, 760, 1293)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3395)
[M::mem_pestat] mean and std.dev: (734.82, 516.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4446)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 155, #reads = 1066196 mem = 536883112 peak = 1075662848
[M::process] read 702270 sequences (100000276 bp) in 2.183 CPU sec, 2.259 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 284043, 16, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 252, 395)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 859)
[M::mem_pestat] mean and std.dev: (292.35, 176.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1091)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 222, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 669)
[M::mem_pestat] mean and std.dev: (248.33, 122.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 841)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (793, 1313, 1685)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3469)
[M::mem_pestat] mean and std.dev: (1018.71, 692.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4361)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 373, 518)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1096)
[M::mem_pestat] mean and std.dev: (405.29, 268.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1477)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703292 sequences (100000066 bp) in 1.870 CPU sec, 1.877 real sec...
[M::mem_process_seqs] Processed 700698 reads in 205.904 CPU sec, 6.541 real sec
[M::mem_process_seqs] Processed 702348 reads in 134.781 CPU sec, 4.257 real sec
sorting block 156, #reads = 1066929 mem = 536879275 peak = 1075662848
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 283860, 33, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 189, 490)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1164)
[M::mem_pestat] mean and std.dev: (321.39, 275.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1501)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 221, 323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 665)
[M::mem_pestat] mean and std.dev: (247.56, 122.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 836)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 431, 2283)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6501)
[M::mem_pestat] mean and std.dev: (1250.18, 1504.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8610)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 455, 930)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2342)
[M::mem_pestat] mean and std.dev: (595.68, 549.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3048)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703344 sequences (100000254 bp) in 2.525 CPU sec, 2.659 real sec...
[M::process] read 702428 sequences (100000212 bp) in 1.960 CPU sec, 1.956 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 284796, 27, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 518, 2130)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6034)
[M::mem_pestat] mean and std.dev: (1042.55, 1163.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7986)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 218, 318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 652)
[M::mem_pestat] mean and std.dev: (244.19, 119.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 819)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 494, 1049)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2767)
[M::mem_pestat] mean and std.dev: (608.92, 619.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3626)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (279, 451, 1057)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2613)
[M::mem_pestat] mean and std.dev: (656.46, 583.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3391)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702270 reads in 183.692 CPU sec, 5.824 real sec
[M::mem_process_seqs] Processed 703292 reads in 120.216 CPU sec, 3.917 real sec
sorting block 157, #reads = 1070223 mem = 536880978 peak = 1075662848
[M::process] read 702086 sequences (100000276 bp) in 2.090 CPU sec, 2.175 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 284631, 23, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 434, 2476)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7070)
[M::mem_pestat] mean and std.dev: (1175.00, 1317.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9367)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 218, 315)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 643)
[M::mem_pestat] mean and std.dev: (242.37, 116.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 807)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (437, 485, 1648)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4070)
[M::mem_pestat] mean and std.dev: (811.50, 719.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5281)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (231, 542, 1195)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3123)
[M::mem_pestat] mean and std.dev: (690.65, 576.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4087)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700866 sequences (100000026 bp) in 1.494 CPU sec, 1.503 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 283874, 24, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 270, 556)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1364)
[M::mem_pestat] mean and std.dev: (280.97, 214.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1768)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 221, 318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 648)
[M::mem_pestat] mean and std.dev: (244.74, 117.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 813)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 514, 924)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2342)
[M::mem_pestat] mean and std.dev: (543.52, 487.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3051)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 500, 1021)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2641)
[M::mem_pestat] mean and std.dev: (611.05, 462.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3451)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 284085, 21, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (145, 516, 2893)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8389)
[M::mem_pestat] mean and std.dev: (1352.58, 1724.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11137)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 222, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 657)
[M::mem_pestat] mean and std.dev: (246.21, 119.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 825)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 271, 1494)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4094)
[M::mem_pestat] mean and std.dev: (790.75, 851.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5394)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 278, 551)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1255)
[M::mem_pestat] mean and std.dev: (276.41, 132.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1607)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703344 reads in 255.670 CPU sec, 8.285 real sec
sorting block 158, #reads = 1070466 mem = 536885104 peak = 1075662848
[M::mem_process_seqs] Processed 702428 reads in 191.384 CPU sec, 6.141 real sec
[M::mem_process_seqs] Processed 702086 reads in 210.731 CPU sec, 6.775 real sec
sorting block 159, #reads = 1068405 mem = 536879873 peak = 1075662848
[M::process] read 699512 sequences (100000170 bp) in 2.459 CPU sec, 2.612 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 283564, 23, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 238, 1044)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2838)
[M::mem_pestat] mean and std.dev: (467.13, 465.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3735)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 224, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 664)
[M::mem_pestat] mean and std.dev: (248.52, 119.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 834)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (413, 649, 922)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1940)
[M::mem_pestat] mean and std.dev: (576.64, 313.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2449)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 892, 2420)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6892)
[M::mem_pestat] mean and std.dev: (1301.20, 1486.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9128)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698546 sequences (100000190 bp) in 1.855 CPU sec, 1.972 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 283140, 32, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 326, 940)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2488)
[M::mem_pestat] mean and std.dev: (545.83, 580.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3262)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 230, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 682)
[M::mem_pestat] mean and std.dev: (253.96, 123.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 857)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (346, 567, 1800)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4708)
[M::mem_pestat] mean and std.dev: (873.55, 906.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6162)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 266, 1033)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2699)
[M::mem_pestat] mean and std.dev: (531.71, 501.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3532)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700866 reads in 167.870 CPU sec, 5.361 real sec
sorting block 160, #reads = 1069697 mem = 536882299 peak = 1075662848
[M::process] read 700204 sequences (100000079 bp) in 1.640 CPU sec, 1.684 real sec...
[M::mem_process_seqs] Processed 699512 reads in 112.818 CPU sec, 3.559 real sec
sorting block 161, #reads = 1070187 mem = 536883711 peak = 1075662848
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 282883, 35, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (233, 350, 1033)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2633)
[M::mem_pestat] mean and std.dev: (445.14, 355.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3433)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 233, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 693)
[M::mem_pestat] mean and std.dev: (257.39, 124.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 871)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (251, 748, 1138)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2912)
[M::mem_pestat] mean and std.dev: (704.84, 683.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3799)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 283, 649)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1601)
[M::mem_pestat] mean and std.dev: (372.31, 297.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2077)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699992 sequences (100000293 bp) in 2.252 CPU sec, 2.452 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 283470, 31, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 392, 907)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2333)
[M::mem_pestat] mean and std.dev: (551.16, 454.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3046)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 227, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 672)
[M::mem_pestat] mean and std.dev: (251.48, 121.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 844)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (469, 721, 1040)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2182)
[M::mem_pestat] mean and std.dev: (750.14, 432.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2753)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 361, 1030)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2654)
[M::mem_pestat] mean and std.dev: (602.02, 517.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3466)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699482 sequences (100000161 bp) in 1.856 CPU sec, 1.858 real sec...
[M::mem_process_seqs] Processed 698546 reads in 166.847 CPU sec, 5.448 real sec
[M::mem_process_seqs] Processed 700204 reads in 107.837 CPU sec, 3.415 real sec
sorting block 162, #reads = 1068795 mem = 536884794 peak = 1075662848
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 283404, 16, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 316, 860)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2148)
[M::mem_pestat] mean and std.dev: (521.49, 470.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2792)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 227, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 675)
[M::mem_pestat] mean and std.dev: (251.78, 122.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 848)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (671, 1035, 1496)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3146)
[M::mem_pestat] mean and std.dev: (1099.81, 660.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3971)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 582, 1063)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2789)
[M::mem_pestat] mean and std.dev: (551.47, 390.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3652)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698404 sequences (100000146 bp) in 2.558 CPU sec, 2.701 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 282757, 26, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (146, 302, 640)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1628)
[M::mem_pestat] mean and std.dev: (319.62, 265.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2122)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 228, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 678)
[M::mem_pestat] mean and std.dev: (252.63, 122.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 852)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (129, 407, 1451)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4095)
[M::mem_pestat] mean and std.dev: (776.04, 995.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5417)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 353, 1574)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4400)
[M::mem_pestat] mean and std.dev: (807.79, 876.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5813)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699992 reads in 158.625 CPU sec, 5.128 real sec
[M::process] read 699220 sequences (100000019 bp) in 1.942 CPU sec, 1.956 real sec...
[M::mem_process_seqs] Processed 699482 reads in 103.880 CPU sec, 3.275 real sec
sorting block 163, #reads = 1070561 mem = 536877766 peak = 1075662848
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 282460, 19, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 343, 2204)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6284)
[M::mem_pestat] mean and std.dev: (1175.11, 1576.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8324)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 231, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 689)
[M::mem_pestat] mean and std.dev: (256.17, 124.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 866)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (645, 731, 2824)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7182)
[M::mem_pestat] mean and std.dev: (1536.53, 1422.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9361)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 250, 319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 593)
[M::mem_pestat] mean and std.dev: (212.95, 66.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 730)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698968 sequences (100000077 bp) in 2.027 CPU sec, 2.139 real sec...
[M::process] read 698684 sequences (100000181 bp) in 1.430 CPU sec, 1.427 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 282476, 34, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (276, 398, 1688)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4512)
[M::mem_pestat] mean and std.dev: (947.53, 1100.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5924)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 229, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 676)
[M::mem_pestat] mean and std.dev: (253.08, 122.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 849)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (227, 740, 951)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2399)
[M::mem_pestat] mean and std.dev: (593.80, 521.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3123)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 465, 1050)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2822)
[M::mem_pestat] mean and std.dev: (611.67, 623.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3708)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698404 reads in 162.763 CPU sec, 5.295 real sec
sorting block 164, #reads = 1069852 mem = 536881022 peak = 1075662848
[M::mem_process_seqs] Processed 699220 reads in 102.123 CPU sec, 3.251 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (18, 282761, 20, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (134, 199, 292)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 608)
[M::mem_pestat] mean and std.dev: (197.19, 82.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 766)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 230, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 679)
[M::mem_pestat] mean and std.dev: (253.79, 122.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 853)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (336, 545, 3019)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8385)
[M::mem_pestat] mean and std.dev: (2050.65, 2874.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13548)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (276, 536, 998)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2442)
[M::mem_pestat] mean and std.dev: (647.78, 460.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3164)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 165, #reads = 1070256 mem = 536881198 peak = 1075662848
[M::process] read 698538 sequences (100000056 bp) in 2.085 CPU sec, 2.209 real sec...
[M::process] read 698498 sequences (100000144 bp) in 1.450 CPU sec, 1.450 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 282280, 27, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 289, 821)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2069)
[M::mem_pestat] mean and std.dev: (420.79, 385.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2693)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 231, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 683)
[M::mem_pestat] mean and std.dev: (255.35, 124.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 858)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (443, 902, 2734)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7316)
[M::mem_pestat] mean and std.dev: (1674.30, 1815.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9607)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 382, 1821)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5051)
[M::mem_pestat] mean and std.dev: (948.16, 1053.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6666)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698968 reads in 156.453 CPU sec, 5.001 real sec
[M::mem_process_seqs] Processed 698684 reads in 106.847 CPU sec, 3.413 real sec
sorting block 166, #reads = 1070128 mem = 536877995 peak = 1075662848
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 281571, 16, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 244, 714)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1788)
[M::mem_pestat] mean and std.dev: (347.63, 328.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2325)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 231, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 680)
[M::mem_pestat] mean and std.dev: (254.65, 123.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 854)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (456, 960, 2159)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5565)
[M::mem_pestat] mean and std.dev: (1193.56, 1074.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7268)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 310, 893)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2277)
[M::mem_pestat] mean and std.dev: (405.53, 331.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2969)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698114 sequences (100000081 bp) in 2.266 CPU sec, 2.342 real sec...
[M::process] read 698214 sequences (100000104 bp) in 1.460 CPU sec, 1.455 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 281958, 31, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 381, 1255)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3357)
[M::mem_pestat] mean and std.dev: (710.30, 717.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4408)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 230, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 680)
[M::mem_pestat] mean and std.dev: (254.82, 123.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 854)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (309, 637, 947)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2223)
[M::mem_pestat] mean and std.dev: (588.89, 349.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2861)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (243, 331, 659)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1491)
[M::mem_pestat] mean and std.dev: (370.53, 254.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1907)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698538 reads in 154.998 CPU sec, 4.927 real sec
[M::mem_process_seqs] Processed 698498 reads in 102.138 CPU sec, 3.242 real sec
sorting block 167, #reads = 1068910 mem = 536880507 peak = 1075662848
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23, 282323, 20, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 228, 1617)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4483)
[M::mem_pestat] mean and std.dev: (724.19, 886.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5916)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 230, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 680)
[M::mem_pestat] mean and std.dev: (255.15, 124.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 854)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (82, 812, 2111)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6169)
[M::mem_pestat] mean and std.dev: (1403.60, 1576.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8198)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 347, 399)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 803)
[M::mem_pestat] mean and std.dev: (300.88, 120.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1005)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698146 sequences (100000125 bp) in 2.389 CPU sec, 2.492 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 282020, 17, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 316, 799)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2067)
[M::mem_pestat] mean and std.dev: (470.98, 391.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2701)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 231, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 683)
[M::mem_pestat] mean and std.dev: (255.64, 124.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 858)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 566, 912)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2370)
[M::mem_pestat] mean and std.dev: (431.71, 338.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3099)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 282, 876)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2238)
[M::mem_pestat] mean and std.dev: (541.43, 542.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2919)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697844 sequences (100000115 bp) in 1.957 CPU sec, 1.959 real sec...
[M::mem_process_seqs] Processed 698114 reads in 166.637 CPU sec, 5.521 real sec
sorting block 168, #reads = 1069978 mem = 536881290 peak = 1075662848
[M::mem_process_seqs] Processed 698214 reads in 111.437 CPU sec, 3.538 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 281979, 19, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 429, 655)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1577)
[M::mem_pestat] mean and std.dev: (487.03, 361.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2038)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 230, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 680)
[M::mem_pestat] mean and std.dev: (255.23, 124.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 854)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1039, 1098, 1704)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3034)
[M::mem_pestat] mean and std.dev: (1250.32, 496.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3699)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 287, 1188)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3106)
[M::mem_pestat] mean and std.dev: (540.45, 604.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4065)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 169, #reads = 1069116 mem = 536884137 peak = 1075662848
[M::process] read 698090 sequences (100000054 bp) in 2.387 CPU sec, 2.487 real sec...
[M::process] read 350350 sequences (50070438 bp) in 1.070 CPU sec, 1.065 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 281333, 37, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 269, 389)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 801)
[M::mem_pestat] mean and std.dev: (256.84, 123.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1007)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 232, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 690)
[M::mem_pestat] mean and std.dev: (257.03, 125.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 867)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (341, 574, 1124)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2690)
[M::mem_pestat] mean and std.dev: (702.17, 525.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3473)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 466, 885)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2225)
[M::mem_pestat] mean and std.dev: (552.77, 554.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2895)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698146 reads in 180.391 CPU sec, 5.885 real sec
[M::mem_process_seqs] Processed 697844 reads in 118.915 CPU sec, 3.796 real sec
sorting block 170, #reads = 1069299 mem = 536880584 peak = 1075662848
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 281645, 25, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 280, 502)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1160)
[M::mem_pestat] mean and std.dev: (299.25, 175.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1489)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 230, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 680)
[M::mem_pestat] mean and std.dev: (255.32, 124.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 854)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (605, 1707, 3260)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8570)
[M::mem_pestat] mean and std.dev: (1800.68, 1475.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11225)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 343, 728)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1800)
[M::mem_pestat] mean and std.dev: (469.56, 411.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2336)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698090 reads in 98.752 CPU sec, 3.259 real sec
sorting block 171, #reads = 1069299 mem = 536879212 peak = 1075662848
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (11, 141233, 10, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (246, 339, 1026)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2586)
[M::mem_pestat] mean and std.dev: (443.30, 373.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3366)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 225, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 666)
[M::mem_pestat] mean and std.dev: (250.84, 122.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 836)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (108, 553, 1415)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4029)
[M::mem_pestat] mean and std.dev: (792.70, 769.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5336)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (233, 244, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (29, 539)
[M::mem_pestat] mean and std.dev: (238.75, 55.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 641)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 350350 reads in 69.750 CPU sec, 2.337 real sec
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000a06d1
  features: 1f8bfbff fffab20b
  extended: f1bf27eb 1b407f7e
  amd bits: 2c100800 00000121
     brand: Intel(R) Xeon(R) 6975P-C
threads: 31
algo: bwa-mem
license: sentieon:klib=31
reads: 183157954
overall: 70398537728 mem 30279.522 user 667.462 sys 1024.790 real
[main] Version: 0.7.17-r1188
[main] CMD: /opt/conda/share/sentieon-202308.03-3/libexec/bwa mem -K 100000000 -Y -R @RG\tID:A23MHWWLT4.1029_HTI-T1-TDNA-1_A23MHWWLT4_1.L008\tPU:L008\tSM:1029_HTI-T1-TDNA-1_A23MHWWLT4_1\tLB:1029_HTI-T1-TDNA-1_A23MHWWLT4_1\tDS:s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta\tPL:ILLUMINA -t 31 ./BWAIndex/Homo_sapiens_assembly38.fasta.64 1029_HTI-T1-TDNA-1_A23MHWWLT4_1_R1.fastq.gz 1029_HTI-T1-TDNA-1_A23MHWWLT4_1_R2.fastq.gz
[main] Real time: 1024.831 sec; CPU: 30946.986 sec
sorting block 172, #reads = 381757 mem = 192618532 peak = 1075662848
uniq header count 1
merging 173 blocks
sw version: sentieon-genomics-202308.03
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000a06d1
  features: 1f8bfbff fffab20b
  extended: f1bf27eb 1b407f7e
  amd bits: 2c100800 00000121
     brand: Intel(R) Xeon(R) 6975P-C
threads: 31 max 192
algo: util-sort
license: sentieon:util=1
output file size: 10166922234
output reads: 184601911
bam_mem_sort: 173 calls 120.598 user 2.761 sys 127.629 real
bam_write: 173 calls 96.561 user 7.245 sys 203.259 real
execute: 1 calls 43.669 user 1.758 sys 1080.106 real
merge_files: 1 calls 43.650 user 1.724 sys 55.008 real
parse_chunk: 2758 calls 123.608 user 34.937 sys 203.820 real
read_chunk: 7461 calls 64.116 user 44.928 sys 967.162 real
sort_block: 1 calls 45.237 user 44.032 sys 940.915 real
write_chunk: 4701 calls 43.188 user 1.394 sys 53.806 real
overall: 3780972544 mem 2285.476 user 117.154 sys 1080.127 real
ls: cannot access '*.cram': No such file or directory