.command.log - Workdir - DAQ:SENTIEON_BWAMEM (1136_4GR-T1-TDNA-1_A23MHWWLT4_1;L007;0001)

File Info

Filename: .command.log
Full Path: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/5b/79667d84b00e84ce6318a747b2db29/.command.log
Size: 316.8 KB
Task: DAQ:SENTIEON_BWAMEM (1136_4GR-T1-TDNA-1_A23MHWWLT4_1;L007;0001)
Attempt
Content

  Downloading: s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/db/e68d702c8199f5d935eedc53232d30/1136_4GR-T1-TDNA-1_A23MHWWLT4_1/1136_4GR-T1-TDNA-1_A23MHWWLT4_1_R2.fastq.gz
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/5b/79667d84b00e84ce6318a747b2db29/.command.sh
  Downloading: s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta.fai
  Downloading: s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/BWAIndex
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/5b/79667d84b00e84ce6318a747b2db29/.command.run
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/db/e68d702c8199f5d935eedc53232d30/1136_4GR-T1-TDNA-1_A23MHWWLT4_1/1136_4GR-T1-TDNA-1_A23MHWWLT4_1_R1.fastq.gz
==> STAGING COMPLETE (7 inputs)

This software is licensed to bgold@natera.com by Sentieon Inc.
cmdline: /opt/conda/share/sentieon-202308.03-3/libexec/util sort -r Homo_sapiens_assembly38.fasta -t 31 -o 1136_4GR-T1-TDNA-1_A23MHWWLT4_1.bam --sam2bam -
This software is licensed to bgold@natera.com by Sentieon Inc.
version: sentieon-genomics-202308.03
[M::bwa_idx_load_from_disk] read 3171 ALT contigs
[M::main_mem] bwa index loaded in 2698.431 CPU sec, 95.814 real sec
[M::process] read 700944 sequences (100000152 bp) in 1.053 CPU sec, 1.057 real sec...
[M::process] read 699546 sequences (100000275 bp) in 1.673 CPU sec, 1.701 real sec...
[M::process] read 699240 sequences (100000177 bp) in 1.654 CPU sec, 1.712 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 285387, 28, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (131, 268, 507)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1259)
[M::mem_pestat] mean and std.dev: (296.55, 222.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1635)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 232, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 717)
[M::mem_pestat] mean and std.dev: (260.44, 132.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 904)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (133, 432, 1157)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3205)
[M::mem_pestat] mean and std.dev: (498.41, 439.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4229)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 369, 915)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2323)
[M::mem_pestat] mean and std.dev: (564.24, 528.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3027)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698786 sequences (100000201 bp) in 1.639 CPU sec, 1.688 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 284887, 32, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 302, 1437)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3913)
[M::mem_pestat] mean and std.dev: (715.76, 705.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5151)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 236, 348)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 728)
[M::mem_pestat] mean and std.dev: (264.01, 134.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 918)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (476, 704, 2230)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5738)
[M::mem_pestat] mean and std.dev: (1178.00, 1019.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7492)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 293, 573)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1373)
[M::mem_pestat] mean and std.dev: (359.78, 206.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1773)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 283962, 22, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (233, 435, 601)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1337)
[M::mem_pestat] mean and std.dev: (397.35, 254.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1705)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 238, 351)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 735)
[M::mem_pestat] mean and std.dev: (265.86, 135.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 927)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (112, 614, 2253)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6535)
[M::mem_pestat] mean and std.dev: (1104.45, 1151.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8676)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 335, 951)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2477)
[M::mem_pestat] mean and std.dev: (600.36, 583.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3240)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700944 reads in 313.998 CPU sec, 10.197 real sec
[M::mem_process_seqs] Processed 699546 reads in 208.618 CPU sec, 6.832 real sec
[M::mem_process_seqs] Processed 699240 reads in 230.293 CPU sec, 7.538 real sec
sorting block 0, #reads = 1078882 mem = 536881334 peak = 579788800
[M::process] read 697700 sequences (100000066 bp) in 2.689 CPU sec, 2.876 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 284543, 31, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (238, 481, 1911)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5257)
[M::mem_pestat] mean and std.dev: (976.06, 893.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6930)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 241, 355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 745)
[M::mem_pestat] mean and std.dev: (268.57, 136.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 940)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (87, 658, 1136)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3234)
[M::mem_pestat] mean and std.dev: (753.61, 794.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4283)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 313, 1205)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3195)
[M::mem_pestat] mean and std.dev: (640.15, 727.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4190)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697138 sequences (100000136 bp) in 2.416 CPU sec, 2.517 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 283892, 19, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (226, 722, 1363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3637)
[M::mem_pestat] mean and std.dev: (781.50, 658.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4774)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 244, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 750)
[M::mem_pestat] mean and std.dev: (270.89, 137.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 946)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (20, 182, 1264)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3752)
[M::mem_pestat] mean and std.dev: (469.59, 597.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4996)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 260, 396)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 888)
[M::mem_pestat] mean and std.dev: (296.09, 193.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1134)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698786 reads in 189.890 CPU sec, 6.040 real sec
sorting block 1, #reads = 1078156 mem = 536879941 peak = 762241024
[M::process] read 696742 sequences (100000155 bp) in 1.743 CPU sec, 1.784 real sec...
[M::mem_process_seqs] Processed 697700 reads in 126.926 CPU sec, 4.010 real sec
sorting block 2, #reads = 1077050 mem = 536878538 peak = 865079296
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 283887, 14, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 400, 904)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2342)
[M::mem_pestat] mean and std.dev: (559.68, 491.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3061)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 244, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 750)
[M::mem_pestat] mean and std.dev: (271.31, 137.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 946)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (363, 517, 985)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2229)
[M::mem_pestat] mean and std.dev: (583.50, 358.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2851)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 301, 1164)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3044)
[M::mem_pestat] mean and std.dev: (573.35, 651.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3984)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695652 sequences (100000237 bp) in 2.536 CPU sec, 2.758 real sec...
[M::process] read 695688 sequences (100000206 bp) in 1.749 CPU sec, 1.766 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (22, 283549, 16, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 439, 743)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1873)
[M::mem_pestat] mean and std.dev: (491.05, 361.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2438)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 246, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 763)
[M::mem_pestat] mean and std.dev: (274.31, 139.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 963)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (359, 585, 1152)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2738)
[M::mem_pestat] mean and std.dev: (666.56, 464.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3531)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (249, 370, 748)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1746)
[M::mem_pestat] mean and std.dev: (519.67, 383.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2245)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697138 reads in 190.599 CPU sec, 6.169 real sec
[M::mem_process_seqs] Processed 696742 reads in 125.796 CPU sec, 4.012 real sec
sorting block 3, #reads = 1076263 mem = 536879615 peak = 865079296
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 282903, 22, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 473, 732)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1876)
[M::mem_pestat] mean and std.dev: (476.68, 388.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2448)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 250, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 768)
[M::mem_pestat] mean and std.dev: (277.12, 140.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 969)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 679, 1402)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3846)
[M::mem_pestat] mean and std.dev: (850.27, 714.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5068)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 176, 429)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 963)
[M::mem_pestat] mean and std.dev: (243.14, 134.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1230)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695760 sequences (100000143 bp) in 2.320 CPU sec, 2.433 real sec...
[M::process] read 695600 sequences (100000301 bp) in 1.821 CPU sec, 1.825 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 282798, 26, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (542, 731, 2214)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5558)
[M::mem_pestat] mean and std.dev: (1403.46, 1394.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7230)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 249, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 765)
[M::mem_pestat] mean and std.dev: (275.92, 139.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 965)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 375, 857)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2265)
[M::mem_pestat] mean and std.dev: (490.39, 453.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2969)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (256, 471, 1134)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2890)
[M::mem_pestat] mean and std.dev: (577.72, 442.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3768)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695652 reads in 192.509 CPU sec, 6.211 real sec
[M::mem_process_seqs] Processed 695688 reads in 128.909 CPU sec, 4.116 real sec
sorting block 4, #reads = 1075338 mem = 536880287 peak = 865079296
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 283153, 16, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 284, 616)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1476)
[M::mem_pestat] mean and std.dev: (343.15, 290.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1906)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 249, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 765)
[M::mem_pestat] mean and std.dev: (276.26, 139.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 965)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (93, 371, 1829)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5301)
[M::mem_pestat] mean and std.dev: (428.00, 556.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7037)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (337, 773, 3889)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10993)
[M::mem_pestat] mean and std.dev: (2456.28, 2999.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14545)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696132 sequences (100000292 bp) in 2.371 CPU sec, 2.495 real sec...
[M::process] read 695358 sequences (100000036 bp) in 1.856 CPU sec, 1.860 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 283593, 24, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (247, 443, 782)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1852)
[M::mem_pestat] mean and std.dev: (424.75, 274.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2387)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 249, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 768)
[M::mem_pestat] mean and std.dev: (277.42, 141.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 969)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 541, 974)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2558)
[M::mem_pestat] mean and std.dev: (461.29, 424.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3350)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 495, 1043)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2695)
[M::mem_pestat] mean and std.dev: (805.68, 763.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3858)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695760 reads in 184.294 CPU sec, 5.916 real sec
sorting block 5, #reads = 1075082 mem = 536882596 peak = 865079296
[M::mem_process_seqs] Processed 695600 reads in 122.704 CPU sec, 3.996 real sec
sorting block 6, #reads = 1074450 mem = 536883080 peak = 897064960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 283242, 16, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 795, 1147)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3047)
[M::mem_pestat] mean and std.dev: (651.30, 530.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3997)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 247, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 753)
[M::mem_pestat] mean and std.dev: (274.00, 138.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 949)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (300, 702, 1172)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2916)
[M::mem_pestat] mean and std.dev: (599.43, 469.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3788)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 237, 910)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2384)
[M::mem_pestat] mean and std.dev: (499.71, 449.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3121)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695044 sequences (100000299 bp) in 2.549 CPU sec, 2.768 real sec...
[M::process] read 694852 sequences (100000301 bp) in 1.962 CPU sec, 1.972 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 282883, 26, 22)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 668, 1073)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2827)
[M::mem_pestat] mean and std.dev: (632.21, 488.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3704)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 251, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 769)
[M::mem_pestat] mean and std.dev: (278.04, 140.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 970)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 521, 1554)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4246)
[M::mem_pestat] mean and std.dev: (856.36, 875.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5592)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 360, 601)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1383)
[M::mem_pestat] mean and std.dev: (366.86, 195.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1774)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696132 reads in 195.452 CPU sec, 6.301 real sec
[M::mem_process_seqs] Processed 695358 reads in 131.299 CPU sec, 4.251 real sec
sorting block 7, #reads = 1075581 mem = 536882310 peak = 897064960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 282843, 23, 18)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 356, 759)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1865)
[M::mem_pestat] mean and std.dev: (447.68, 407.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2418)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 250, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 764)
[M::mem_pestat] mean and std.dev: (277.18, 139.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 963)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (122, 310, 651)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1709)
[M::mem_pestat] mean and std.dev: (383.52, 358.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2238)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (359, 877, 1673)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4301)
[M::mem_pestat] mean and std.dev: (1021.35, 937.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5615)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694936 sequences (100000222 bp) in 2.588 CPU sec, 3.075 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 282868, 29, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 380, 992)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2574)
[M::mem_pestat] mean and std.dev: (536.97, 528.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3365)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 251, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 758)
[M::mem_pestat] mean and std.dev: (276.69, 138.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 955)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (109, 395, 1569)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4489)
[M::mem_pestat] mean and std.dev: (912.62, 891.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5949)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 276, 438)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1012)
[M::mem_pestat] mean and std.dev: (319.52, 186.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1299)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694892 sequences (100000289 bp) in 1.914 CPU sec, 1.916 real sec...
[M::mem_process_seqs] Processed 695044 reads in 198.091 CPU sec, 6.447 real sec
[M::mem_process_seqs] Processed 694852 reads in 130.030 CPU sec, 4.225 real sec
sorting block 8, #reads = 1074695 mem = 536877791 peak = 897064960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 282204, 23, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (250, 355, 1184)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3052)
[M::mem_pestat] mean and std.dev: (652.06, 588.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3986)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 249, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 751)
[M::mem_pestat] mean and std.dev: (274.58, 136.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 946)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (96, 367, 1137)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3219)
[M::mem_pestat] mean and std.dev: (713.26, 792.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4260)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 389, 973)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2495)
[M::mem_pestat] mean and std.dev: (545.82, 482.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3256)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695140 sequences (100000060 bp) in 2.940 CPU sec, 3.244 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 282455, 21, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (225, 338, 524)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1122)
[M::mem_pestat] mean and std.dev: (326.78, 183.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1421)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 250, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 758)
[M::mem_pestat] mean and std.dev: (275.93, 137.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 955)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (251, 551, 2025)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5573)
[M::mem_pestat] mean and std.dev: (1057.30, 1359.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7347)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (280, 572, 894)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2122)
[M::mem_pestat] mean and std.dev: (667.48, 568.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2942)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695870 sequences (100000231 bp) in 1.954 CPU sec, 1.956 real sec...
[M::mem_process_seqs] Processed 694936 reads in 206.896 CPU sec, 6.712 real sec
sorting block 9, #reads = 1075926 mem = 536879086 peak = 897064960
[M::mem_process_seqs] Processed 694892 reads in 130.726 CPU sec, 4.252 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 283270, 27, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (306, 489, 1188)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2952)
[M::mem_pestat] mean and std.dev: (678.76, 496.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3834)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 249, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 757)
[M::mem_pestat] mean and std.dev: (275.49, 138.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 954)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (513, 896, 2290)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5844)
[M::mem_pestat] mean and std.dev: (1475.07, 1331.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7621)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 266, 642)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1522)
[M::mem_pestat] mean and std.dev: (275.16, 146.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1962)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695458 sequences (100000253 bp) in 2.823 CPU sec, 3.132 real sec...
sorting block 10, #reads = 1074296 mem = 536887383 peak = 897064960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 283092, 8, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (243, 473, 862)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2100)
[M::mem_pestat] mean and std.dev: (614.78, 438.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2719)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 247, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 747)
[M::mem_pestat] mean and std.dev: (273.04, 136.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 941)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (260, 505, 1053)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2639)
[M::mem_pestat] mean and std.dev: (659.03, 534.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3432)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 695514 sequences (100000120 bp) in 2.157 CPU sec, 2.188 real sec...
[M::mem_process_seqs] Processed 695140 reads in 208.215 CPU sec, 6.754 real sec
[M::mem_process_seqs] Processed 695870 reads in 133.989 CPU sec, 4.329 real sec
sorting block 11, #reads = 1074295 mem = 536882673 peak = 897064960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 282830, 24, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (270, 430, 1967)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5361)
[M::mem_pestat] mean and std.dev: (1155.71, 1159.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7058)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 248, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 756)
[M::mem_pestat] mean and std.dev: (274.53, 137.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 953)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (327, 1373, 3970)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 11256)
[M::mem_pestat] mean and std.dev: (2228.33, 2616.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14899)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (239, 395, 1191)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3095)
[M::mem_pestat] mean and std.dev: (643.96, 612.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4047)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695304 sequences (100000183 bp) in 2.775 CPU sec, 2.993 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 282044, 24, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 456, 1505)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4149)
[M::mem_pestat] mean and std.dev: (752.00, 724.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5471)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::process] read 695310 sequences (100000093 bp) in 2.045 CPU sec, 2.059 real sec...
[M::mem_pestat] (25, 50, 75) percentile: (166, 248, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 748)
[M::mem_pestat] mean and std.dev: (273.56, 136.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 942)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (409, 622, 816)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1630)
[M::mem_pestat] mean and std.dev: (505.29, 349.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2037)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (266, 336, 643)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1397)
[M::mem_pestat] mean and std.dev: (415.10, 242.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1774)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695458 reads in 203.310 CPU sec, 6.574 real sec
[M::mem_process_seqs] Processed 695514 reads in 135.087 CPU sec, 4.366 real sec
sorting block 12, #reads = 1073743 mem = 536877488 peak = 897064960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (19, 282629, 20, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (329, 681, 1670)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4352)
[M::mem_pestat] mean and std.dev: (875.06, 674.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5693)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 249, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 754)
[M::mem_pestat] mean and std.dev: (274.85, 137.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 950)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (360, 1219, 2272)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6096)
[M::mem_pestat] mean and std.dev: (1086.50, 886.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8008)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 324, 657)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1587)
[M::mem_pestat] mean and std.dev: (415.59, 318.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2052)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694938 sequences (100000059 bp) in 2.766 CPU sec, 2.976 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 282516, 39, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (145, 535, 1030)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2800)
[M::mem_pestat] mean and std.dev: (671.00, 622.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3685)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 249, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 763)
[M::mem_pestat] mean and std.dev: (276.32, 139.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 962)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (97, 247, 709)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1933)
[M::mem_pestat] mean and std.dev: (466.65, 530.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2589)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 319, 1047)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2767)
[M::mem_pestat] mean and std.dev: (587.31, 654.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3627)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698914 sequences (100000096 bp) in 2.069 CPU sec, 2.078 real sec...
[M::mem_process_seqs] Processed 695304 reads in 202.297 CPU sec, 6.519 real sec
[M::mem_process_seqs] Processed 695310 reads in 137.243 CPU sec, 4.442 real sec
sorting block 13, #reads = 1072087 mem = 536881313 peak = 897064960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 282443, 23, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (287, 495, 2654)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7388)
[M::mem_pestat] mean and std.dev: (971.03, 1190.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9755)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 251, 368)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 770)
[M::mem_pestat] mean and std.dev: (278.64, 141.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 971)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (48, 340, 659)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1881)
[M::mem_pestat] mean and std.dev: (427.32, 471.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2492)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 292, 440)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 916)
[M::mem_pestat] mean and std.dev: (306.70, 163.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1154)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 14, #reads = 1073224 mem = 536881406 peak = 897064960
[M::process] read 700156 sequences (100000081 bp) in 2.812 CPU sec, 3.025 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 284377, 31, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 429, 815)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2001)
[M::mem_pestat] mean and std.dev: (434.33, 283.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2594)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 239, 353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 739)
[M::mem_pestat] mean and std.dev: (266.80, 135.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 932)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 387, 935)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2381)
[M::mem_pestat] mean and std.dev: (578.90, 503.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3104)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 336, 1158)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3084)
[M::mem_pestat] mean and std.dev: (529.97, 467.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4047)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698486 sequences (100000035 bp) in 2.094 CPU sec, 2.102 real sec...
[M::mem_process_seqs] Processed 694938 reads in 199.979 CPU sec, 6.463 real sec
[M::mem_process_seqs] Processed 698914 reads in 132.751 CPU sec, 4.219 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (21, 284103, 21, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 393, 1094)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2904)
[M::mem_pestat] mean and std.dev: (524.75, 512.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3809)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 236, 350)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 734)
[M::mem_pestat] mean and std.dev: (264.46, 134.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 926)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 269, 1599)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4493)
[M::mem_pestat] mean and std.dev: (772.10, 944.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5940)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 314, 1038)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2672)
[M::mem_pestat] mean and std.dev: (453.20, 410.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3489)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 15, #reads = 1074856 mem = 536877938 peak = 897064960
[M::process] read 697850 sequences (100000130 bp) in 2.722 CPU sec, 2.907 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 284059, 16, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (120, 205, 557)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1431)
[M::mem_pestat] mean and std.dev: (337.96, 330.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1868)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 240, 352)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 736)
[M::mem_pestat] mean and std.dev: (266.74, 134.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 928)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (266, 579, 2665)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7463)
[M::mem_pestat] mean and std.dev: (1553.75, 2025.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9862)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 358, 1292)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3510)
[M::mem_pestat] mean and std.dev: (663.86, 711.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4619)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697256 sequences (100000145 bp) in 1.864 CPU sec, 1.872 real sec...
[M::mem_process_seqs] Processed 700156 reads in 187.505 CPU sec, 5.994 real sec
[M::mem_process_seqs] Processed 698486 reads in 124.844 CPU sec, 3.973 real sec
sorting block 16, #reads = 1079187 mem = 536880944 peak = 897064960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 283817, 25, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (251, 387, 482)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 944)
[M::mem_pestat] mean and std.dev: (348.43, 174.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1175)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 243, 354)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 738)
[M::mem_pestat] mean and std.dev: (268.34, 134.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 930)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (102, 359, 921)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2559)
[M::mem_pestat] mean and std.dev: (497.33, 577.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3378)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (238, 289, 2483)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6973)
[M::mem_pestat] mean and std.dev: (1246.68, 1721.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9218)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697178 sequences (100000184 bp) in 2.845 CPU sec, 3.113 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (18, 284095, 22, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (244, 842, 1221)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3175)
[M::mem_pestat] mean and std.dev: (789.06, 644.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4152)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 244, 356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 744)
[M::mem_pestat] mean and std.dev: (270.17, 135.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 938)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (236, 1032, 2280)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6368)
[M::mem_pestat] mean and std.dev: (1352.95, 1242.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8412)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (299, 494, 964)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2294)
[M::mem_pestat] mean and std.dev: (587.92, 459.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2959)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696962 sequences (100000101 bp) in 2.021 CPU sec, 2.029 real sec...
[M::mem_process_seqs] Processed 697850 reads in 192.408 CPU sec, 6.150 real sec
[M::mem_process_seqs] Processed 697256 reads in 128.524 CPU sec, 4.088 real sec
sorting block 17, #reads = 1079847 mem = 536879813 peak = 897064960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 284274, 15, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 338, 1146)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3064)
[M::mem_pestat] mean and std.dev: (545.17, 533.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4023)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 245, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 748)
[M::mem_pestat] mean and std.dev: (270.90, 135.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 943)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (127, 548, 975)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2671)
[M::mem_pestat] mean and std.dev: (526.00, 462.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3519)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (236, 275, 443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 857)
[M::mem_pestat] mean and std.dev: (304.34, 123.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1064)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696436 sequences (100000161 bp) in 2.995 CPU sec, 3.195 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 283980, 19, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 282, 737)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1841)
[M::mem_pestat] mean and std.dev: (561.05, 551.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2769)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 247, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 755)
[M::mem_pestat] mean and std.dev: (272.86, 137.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 952)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 835, 1950)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5534)
[M::mem_pestat] mean and std.dev: (1503.16, 1765.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8564)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 331, 1550)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4218)
[M::mem_pestat] mean and std.dev: (859.88, 1086.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5552)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697178 reads in 190.695 CPU sec, 6.095 real sec
[M::process] read 696558 sequences (100000019 bp) in 1.922 CPU sec, 1.928 real sec...
sorting block 18, #reads = 1079278 mem = 536878875 peak = 897064960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 283406, 12, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 507, 585)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1425)
[M::mem_pestat] mean and std.dev: (295.10, 175.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1845)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 248, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 761)
[M::mem_pestat] mean and std.dev: (274.57, 138.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 960)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (245, 823, 1473)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3929)
[M::mem_pestat] mean and std.dev: (835.82, 781.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5157)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (250, 341, 484)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 952)
[M::mem_pestat] mean and std.dev: (344.81, 136.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1186)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695948 sequences (100000297 bp) in 2.202 CPU sec, 2.208 real sec...
[M::mem_process_seqs] Processed 696436 reads in 111.188 CPU sec, 3.752 real sec
sorting block 19, #reads = 1077721 mem = 536878937 peak = 897064960
[M::mem_process_seqs] Processed 696962 reads in 283.502 CPU sec, 9.249 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 283731, 29, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 377, 1540)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4216)
[M::mem_pestat] mean and std.dev: (870.52, 999.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5554)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 249, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 767)
[M::mem_pestat] mean and std.dev: (275.57, 139.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 968)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (505, 887, 1735)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4195)
[M::mem_pestat] mean and std.dev: (1245.30, 1136.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5792)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 291, 479)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1059)
[M::mem_pestat] mean and std.dev: (318.56, 170.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1349)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695482 sequences (100000085 bp) in 2.836 CPU sec, 3.027 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 282912, 18, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 290, 812)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2064)
[M::mem_pestat] mean and std.dev: (350.93, 264.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2690)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 249, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 759)
[M::mem_pestat] mean and std.dev: (275.17, 138.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 957)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 498, 1282)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3492)
[M::mem_pestat] mean and std.dev: (605.17, 531.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4597)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 420, 1228)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3252)
[M::mem_pestat] mean and std.dev: (560.58, 531.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4264)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696558 reads in 212.474 CPU sec, 6.790 real sec
sorting block 20, #reads = 1077842 mem = 536877955 peak = 897064960
[M::process] read 695810 sequences (100000096 bp) in 1.855 CPU sec, 1.926 real sec...
[M::mem_process_seqs] Processed 695948 reads in 129.950 CPU sec, 4.147 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 283075, 16, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 287, 1621)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4485)
[M::mem_pestat] mean and std.dev: (636.75, 624.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5917)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 251, 368)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 772)
[M::mem_pestat] mean and std.dev: (277.98, 140.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 974)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (87, 275, 1566)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4524)
[M::mem_pestat] mean and std.dev: (961.50, 1300.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6163)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 281, 932)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2422)
[M::mem_pestat] mean and std.dev: (513.17, 378.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3167)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 21, #reads = 1077165 mem = 536880024 peak = 897064960
[M::process] read 695012 sequences (100000031 bp) in 2.950 CPU sec, 3.192 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 283530, 23, 23)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 352, 670)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1682)
[M::mem_pestat] mean and std.dev: (486.14, 417.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2188)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 250, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 766)
[M::mem_pestat] mean and std.dev: (276.82, 139.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 966)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (311, 585, 1967)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5279)
[M::mem_pestat] mean and std.dev: (902.00, 809.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6935)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (277, 452, 1652)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4402)
[M::mem_pestat] mean and std.dev: (911.86, 1075.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5777)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695052 sequences (100000010 bp) in 1.975 CPU sec, 1.978 real sec...
[M::mem_process_seqs] Processed 695482 reads in 200.672 CPU sec, 6.454 real sec
[M::mem_process_seqs] Processed 695810 reads in 133.535 CPU sec, 4.262 real sec
sorting block 22, #reads = 1076068 mem = 536878898 peak = 897064960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 282992, 31, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (245, 298, 881)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2153)
[M::mem_pestat] mean and std.dev: (581.95, 516.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2789)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 252, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 767)
[M::mem_pestat] mean and std.dev: (277.78, 139.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 967)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (100, 282, 811)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2233)
[M::mem_pestat] mean and std.dev: (455.21, 455.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2944)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 382, 639)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1555)
[M::mem_pestat] mean and std.dev: (428.21, 291.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2013)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695134 sequences (100000018 bp) in 2.831 CPU sec, 3.059 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 283062, 34, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 360, 613)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1435)
[M::mem_pestat] mean and std.dev: (373.20, 233.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1846)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 250, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 755)
[M::mem_pestat] mean and std.dev: (275.66, 137.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 951)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (505, 1280, 1414)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3232)
[M::mem_pestat] mean and std.dev: (977.30, 605.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4141)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (240, 395, 1463)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3909)
[M::mem_pestat] mean and std.dev: (775.03, 754.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5132)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694678 sequences (100000003 bp) in 2.155 CPU sec, 2.159 real sec...
[M::mem_process_seqs] Processed 695012 reads in 199.814 CPU sec, 6.398 real sec
[M::mem_process_seqs] Processed 695052 reads in 132.861 CPU sec, 4.217 real sec
sorting block 23, #reads = 1076356 mem = 536880532 peak = 897064960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 282735, 29, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 295, 518)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1214)
[M::mem_pestat] mean and std.dev: (343.98, 217.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1562)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 251, 368)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 770)
[M::mem_pestat] mean and std.dev: (278.23, 140.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 971)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (275, 902, 2397)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6641)
[M::mem_pestat] mean and std.dev: (1232.15, 1136.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8763)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 425, 605)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1383)
[M::mem_pestat] mean and std.dev: (368.65, 206.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1772)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695068 sequences (100000151 bp) in 2.867 CPU sec, 3.110 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 282653, 20, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (406, 887, 2824)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7660)
[M::mem_pestat] mean and std.dev: (1507.56, 1914.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10078)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 252, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 764)
[M::mem_pestat] mean and std.dev: (277.38, 138.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 963)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 269, 979)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2567)
[M::mem_pestat] mean and std.dev: (400.11, 391.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3361)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 300, 739)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1803)
[M::mem_pestat] mean and std.dev: (421.62, 386.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2335)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695402 sequences (100000068 bp) in 1.882 CPU sec, 1.889 real sec...
[M::mem_process_seqs] Processed 695134 reads in 200.086 CPU sec, 6.474 real sec
sorting block 24, #reads = 1075905 mem = 536880797 peak = 897064960
[M::mem_process_seqs] Processed 694678 reads in 132.690 CPU sec, 4.262 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (22, 282768, 18, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (276, 426, 1045)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2583)
[M::mem_pestat] mean and std.dev: (625.45, 507.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3352)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 251, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 764)
[M::mem_pestat] mean and std.dev: (277.76, 139.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 963)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 586, 1181)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3207)
[M::mem_pestat] mean and std.dev: (682.81, 652.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4220)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 491, 1822)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5104)
[M::mem_pestat] mean and std.dev: (869.70, 883.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6745)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 25, #reads = 1074149 mem = 536877106 peak = 897064960
[M::process] read 694920 sequences (100000068 bp) in 3.125 CPU sec, 3.471 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 283261, 18, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 347, 549)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1281)
[M::mem_pestat] mean and std.dev: (393.93, 306.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1647)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 248, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 753)
[M::mem_pestat] mean and std.dev: (274.01, 137.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 949)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (249, 506, 1629)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4389)
[M::mem_pestat] mean and std.dev: (852.33, 803.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5769)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 259, 668)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1612)
[M::mem_pestat] mean and std.dev: (390.49, 349.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2084)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695068 reads in 202.516 CPU sec, 6.517 real sec
[M::process] read 695570 sequences (100000062 bp) in 2.200 CPU sec, 2.231 real sec...
[M::mem_process_seqs] Processed 695402 reads in 139.069 CPU sec, 4.408 real sec
sorting block 26, #reads = 1074292 mem = 536882623 peak = 897064960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 282674, 25, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 383, 936)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2366)
[M::mem_pestat] mean and std.dev: (522.54, 453.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3081)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 250, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 760)
[M::mem_pestat] mean and std.dev: (276.26, 138.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 958)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (510, 1305, 5051)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 14133)
[M::mem_pestat] mean and std.dev: (2335.56, 2152.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 18674)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 282, 904)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2320)
[M::mem_pestat] mean and std.dev: (531.04, 494.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3028)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695294 sequences (100000116 bp) in 2.902 CPU sec, 3.129 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 282951, 30, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 325, 706)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1796)
[M::mem_pestat] mean and std.dev: (386.46, 412.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2341)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 248, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 756)
[M::mem_pestat] mean and std.dev: (274.64, 137.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 953)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 767, 2933)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8401)
[M::mem_pestat] mean and std.dev: (1604.83, 1947.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11135)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (247, 636, 1535)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4111)
[M::mem_pestat] mean and std.dev: (774.04, 665.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5399)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695164 sequences (100000033 bp) in 2.078 CPU sec, 2.079 real sec...
[M::mem_process_seqs] Processed 694920 reads in 206.271 CPU sec, 6.663 real sec
[M::mem_process_seqs] Processed 695570 reads in 135.868 CPU sec, 4.335 real sec
sorting block 27, #reads = 1073590 mem = 536881612 peak = 897064960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 282840, 40, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 430, 1998)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5556)
[M::mem_pestat] mean and std.dev: (861.52, 1001.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7335)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 249, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 757)
[M::mem_pestat] mean and std.dev: (275.50, 138.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 954)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (446, 980, 1829)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4595)
[M::mem_pestat] mean and std.dev: (982.69, 797.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5978)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 243, 397)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 827)
[M::mem_pestat] mean and std.dev: (280.25, 152.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1042)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695224 sequences (100000021 bp) in 3.325 CPU sec, 3.625 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 282836, 33, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 241, 738)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1870)
[M::mem_pestat] mean and std.dev: (475.29, 444.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2436)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 249, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 751)
[M::mem_pestat] mean and std.dev: (274.56, 137.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 946)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (529, 1190, 2485)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6397)
[M::mem_pestat] mean and std.dev: (1396.52, 1096.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8353)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (246, 465, 1463)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3897)
[M::mem_pestat] mean and std.dev: (678.66, 660.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5114)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695294 reads in 197.094 CPU sec, 6.338 real sec
[M::process] read 695610 sequences (100000204 bp) in 2.189 CPU sec, 2.237 real sec...
[M::mem_process_seqs] Processed 695164 reads in 134.890 CPU sec, 4.443 real sec
sorting block 28, #reads = 1074869 mem = 536878248 peak = 897064960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 283178, 22, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 261, 473)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 989)
[M::mem_pestat] mean and std.dev: (324.44, 174.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1247)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 249, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 757)
[M::mem_pestat] mean and std.dev: (275.17, 138.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 954)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 289, 496)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1132)
[M::mem_pestat] mean and std.dev: (287.95, 187.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1450)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 294, 610)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1474)
[M::mem_pestat] mean and std.dev: (287.65, 152.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1906)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 29, #reads = 1073565 mem = 536883963 peak = 897064960
[M::process] read 695780 sequences (100000176 bp) in 3.377 CPU sec, 3.591 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 282896, 30, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 460, 1035)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2707)
[M::mem_pestat] mean and std.dev: (644.38, 542.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3543)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 248, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 762)
[M::mem_pestat] mean and std.dev: (275.80, 140.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 961)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (120, 262, 553)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1419)
[M::mem_pestat] mean and std.dev: (315.86, 298.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1852)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 403, 1371)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3741)
[M::mem_pestat] mean and std.dev: (854.54, 902.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4926)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695224 reads in 195.484 CPU sec, 6.408 real sec
[M::process] read 698882 sequences (100000026 bp) in 2.049 CPU sec, 2.071 real sec...
[M::mem_process_seqs] Processed 695610 reads in 135.893 CPU sec, 4.306 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 282198, 40, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 253, 588)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1436)
[M::mem_pestat] mean and std.dev: (323.36, 275.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1860)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 248, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 768)
[M::mem_pestat] mean and std.dev: (276.59, 141.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 969)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (223, 839, 1726)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4732)
[M::mem_pestat] mean and std.dev: (916.17, 1080.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6235)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (328, 385, 689)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1411)
[M::mem_pestat] mean and std.dev: (376.82, 165.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1772)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 30, #reads = 1073611 mem = 536878865 peak = 897064960
[M::process] read 699100 sequences (100000111 bp) in 3.205 CPU sec, 3.451 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 283987, 15, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 322, 391)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 803)
[M::mem_pestat] mean and std.dev: (287.55, 105.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1009)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 239, 350)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 730)
[M::mem_pestat] mean and std.dev: (265.72, 134.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 920)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (436, 787, 1845)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4663)
[M::mem_pestat] mean and std.dev: (1048.29, 754.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6072)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 316, 1018)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2708)
[M::mem_pestat] mean and std.dev: (581.43, 623.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3553)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695780 reads in 198.584 CPU sec, 6.360 real sec
[M::process] read 698204 sequences (100000044 bp) in 1.911 CPU sec, 1.925 real sec...
[M::mem_process_seqs] Processed 698882 reads in 133.335 CPU sec, 4.235 real sec
sorting block 31, #reads = 1073136 mem = 536883075 peak = 897064960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 284634, 35, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 704, 1529)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4191)
[M::mem_pestat] mean and std.dev: (911.27, 751.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5522)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 239, 348)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 726)
[M::mem_pestat] mean and std.dev: (264.37, 132.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 915)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (307, 1043, 2295)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6271)
[M::mem_pestat] mean and std.dev: (1518.03, 1484.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8259)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 398, 980)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2484)
[M::mem_pestat] mean and std.dev: (492.17, 374.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3236)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697928 sequences (100000053 bp) in 3.160 CPU sec, 3.412 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (22, 284056, 22, 24)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (251, 447, 1150)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2948)
[M::mem_pestat] mean and std.dev: (595.53, 497.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3847)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 242, 353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 737)
[M::mem_pestat] mean and std.dev: (267.68, 134.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 929)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (90, 605, 965)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2715)
[M::mem_pestat] mean and std.dev: (530.37, 467.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3590)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 345, 2060)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5722)
[M::mem_pestat] mean and std.dev: (1165.88, 1423.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7553)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699100 reads in 191.117 CPU sec, 6.143 real sec
[M::mem_process_seqs] Processed 698204 reads in 129.160 CPU sec, 4.089 real sec
[M::process] read 697246 sequences (100000275 bp) in 2.179 CPU sec, 2.246 real sec...
sorting block 32, #reads = 1077687 mem = 536877588 peak = 897064960
[M::process] read 696890 sequences (100000180 bp) in 3.285 CPU sec, 3.637 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 283565, 20, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 579, 1306)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3506)
[M::mem_pestat] mean and std.dev: (734.11, 760.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4606)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 245, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 748)
[M::mem_pestat] mean and std.dev: (271.09, 136.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 943)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (583, 674, 1445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3169)
[M::mem_pestat] mean and std.dev: (641.62, 384.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4031)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 315, 941)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2477)
[M::mem_pestat] mean and std.dev: (485.53, 472.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3245)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697246 reads in 111.453 CPU sec, 3.516 real sec
sorting block 33, #reads = 1078044 mem = 536877636 peak = 897064960
[M::process] read 696320 sequences (100000072 bp) in 2.148 CPU sec, 2.224 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 284275, 23, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 382, 798)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2012)
[M::mem_pestat] mean and std.dev: (450.19, 363.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2619)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 242, 354)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 738)
[M::mem_pestat] mean and std.dev: (268.50, 135.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 930)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (317, 741, 1437)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3677)
[M::mem_pestat] mean and std.dev: (804.36, 598.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4797)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (299, 515, 1332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3398)
[M::mem_pestat] mean and std.dev: (762.94, 651.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4431)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 283765, 32, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (271, 449, 1273)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3277)
[M::mem_pestat] mean and std.dev: (640.56, 496.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4279)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 246, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 754)
[M::mem_pestat] mean and std.dev: (272.55, 137.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 951)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 566, 1660)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4686)
[M::mem_pestat] mean and std.dev: (857.39, 795.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6199)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 393, 1078)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2860)
[M::mem_pestat] mean and std.dev: (676.91, 562.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3751)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697928 reads in 296.543 CPU sec, 9.457 real sec
[M::process] read 696372 sequences (100000087 bp) in 2.476 CPU sec, 2.526 real sec...
[M::mem_process_seqs] Processed 696890 reads in 152.240 CPU sec, 4.831 real sec
sorting block 34, #reads = 1076254 mem = 536879458 peak = 897064960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 283760, 13, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 267, 863)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2199)
[M::mem_pestat] mean and std.dev: (529.00, 504.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2867)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 248, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 756)
[M::mem_pestat] mean and std.dev: (274.07, 137.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 953)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (310, 454, 2420)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6640)
[M::mem_pestat] mean and std.dev: (1063.15, 969.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8750)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 314, 1236)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3270)
[M::mem_pestat] mean and std.dev: (756.08, 899.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4354)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695876 sequences (100000097 bp) in 3.096 CPU sec, 3.362 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 283627, 32, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 202, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 706)
[M::mem_pestat] mean and std.dev: (254.86, 147.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 890)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 248, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 764)
[M::mem_pestat] mean and std.dev: (275.03, 139.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 964)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (324, 1330, 1967)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5253)
[M::mem_pestat] mean and std.dev: (1286.12, 1145.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6896)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 509, 1261)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3347)
[M::mem_pestat] mean and std.dev: (792.31, 657.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4390)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696320 reads in 191.635 CPU sec, 6.140 real sec
[M::process] read 695176 sequences (100000214 bp) in 1.993 CPU sec, 2.026 real sec...
sorting block 35, #reads = 1076396 mem = 536880357 peak = 897064960
[M::mem_process_seqs] Processed 696372 reads in 128.235 CPU sec, 4.100 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 283237, 31, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (259, 517, 1545)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4117)
[M::mem_pestat] mean and std.dev: (771.36, 815.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5403)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 249, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 771)
[M::mem_pestat] mean and std.dev: (277.10, 141.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 973)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (262, 820, 1754)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4738)
[M::mem_pestat] mean and std.dev: (965.22, 1131.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6230)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (249, 622, 1651)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4455)
[M::mem_pestat] mean and std.dev: (936.73, 979.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5857)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 36, #reads = 1078036 mem = 536877470 peak = 897064960
[M::process] read 694838 sequences (100000236 bp) in 2.976 CPU sec, 3.250 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 282981, 20, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 326, 1151)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3093)
[M::mem_pestat] mean and std.dev: (623.76, 612.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4064)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 251, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 767)
[M::mem_pestat] mean and std.dev: (277.69, 139.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 967)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (261, 1639, 2323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6447)
[M::mem_pestat] mean and std.dev: (1293.20, 936.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8509)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 377, 2136)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6070)
[M::mem_pestat] mean and std.dev: (848.93, 1046.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8037)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694858 sequences (100000135 bp) in 2.026 CPU sec, 2.035 real sec...
[M::mem_process_seqs] Processed 695876 reads in 196.678 CPU sec, 6.298 real sec
[M::mem_process_seqs] Processed 695176 reads in 131.929 CPU sec, 4.182 real sec
sorting block 37, #reads = 1077194 mem = 536882606 peak = 897064960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 283203, 18, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (301, 406, 1027)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2479)
[M::mem_pestat] mean and std.dev: (533.29, 358.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3205)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 252, 369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 773)
[M::mem_pestat] mean and std.dev: (279.22, 141.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 975)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (355, 991, 1354)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3352)
[M::mem_pestat] mean and std.dev: (812.00, 539.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4351)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (253, 340, 1002)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2500)
[M::mem_pestat] mean and std.dev: (500.83, 451.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3249)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694628 sequences (100000156 bp) in 2.849 CPU sec, 3.028 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (22, 282747, 31, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (523, 637, 1024)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2026)
[M::mem_pestat] mean and std.dev: (671.89, 399.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2527)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 254, 368)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 770)
[M::mem_pestat] mean and std.dev: (279.15, 140.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 971)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 481, 1488)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4048)
[M::mem_pestat] mean and std.dev: (676.14, 734.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5328)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (443, 846, 1322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3080)
[M::mem_pestat] mean and std.dev: (791.07, 612.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3959)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 694838 reads in 191.848 CPU sec, 6.174 real sec
[M::process] read 693708 sequences (100000225 bp) in 2.024 CPU sec, 2.045 real sec...
[M::mem_process_seqs] Processed 694858 reads in 131.933 CPU sec, 4.229 real sec
sorting block 38, #reads = 1076442 mem = 536882004 peak = 897064960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 282565, 13, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 400, 798)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1970)
[M::mem_pestat] mean and std.dev: (476.25, 413.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2556)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 254, 371)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 777)
[M::mem_pestat] mean and std.dev: (280.43, 141.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 980)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (306, 697, 2497)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6879)
[M::mem_pestat] mean and std.dev: (1132.92, 973.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9070)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (335, 563, 2123)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5699)
[M::mem_pestat] mean and std.dev: (717.65, 608.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7487)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695076 sequences (100000103 bp) in 2.956 CPU sec, 3.205 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 282167, 34, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 267, 770)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1944)
[M::mem_pestat] mean and std.dev: (433.70, 455.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2531)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 254, 368)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 766)
[M::mem_pestat] mean and std.dev: (279.52, 139.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 965)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 851, 4192)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12198)
[M::mem_pestat] mean and std.dev: (1805.44, 2099.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 16201)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (243, 613, 1372)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3630)
[M::mem_pestat] mean and std.dev: (788.03, 656.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4759)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 694628 reads in 194.010 CPU sec, 6.255 real sec
[M::process] read 694672 sequences (100000059 bp) in 2.020 CPU sec, 2.041 real sec...
sorting block 39, #reads = 1076065 mem = 536885965 peak = 897064960
[M::mem_process_seqs] Processed 693708 reads in 131.055 CPU sec, 4.375 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 282832, 22, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 320, 819)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2097)
[M::mem_pestat] mean and std.dev: (471.40, 401.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2736)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 251, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 763)
[M::mem_pestat] mean and std.dev: (276.80, 139.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 962)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (90, 290, 723)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1989)
[M::mem_pestat] mean and std.dev: (389.43, 444.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2622)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (236, 295, 398)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 722)
[M::mem_pestat] mean and std.dev: (310.43, 128.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 884)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 40, #reads = 1074526 mem = 536880293 peak = 897064960
[M::process] read 694884 sequences (100000177 bp) in 2.903 CPU sec, 3.146 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 282820, 29, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (271, 569, 1291)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3331)
[M::mem_pestat] mean and std.dev: (728.86, 614.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4351)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 250, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 758)
[M::mem_pestat] mean and std.dev: (276.12, 138.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 955)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (235, 958, 1377)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3661)
[M::mem_pestat] mean and std.dev: (727.57, 515.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4803)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (242, 492, 888)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2180)
[M::mem_pestat] mean and std.dev: (586.68, 443.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2826)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695194 sequences (100000042 bp) in 2.094 CPU sec, 2.105 real sec...
[M::mem_process_seqs] Processed 695076 reads in 202.722 CPU sec, 6.720 real sec
[M::mem_process_seqs] Processed 694672 reads in 133.593 CPU sec, 4.326 real sec
sorting block 41, #reads = 1075080 mem = 536878530 peak = 897064960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 282708, 18, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (295, 393, 727)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1591)
[M::mem_pestat] mean and std.dev: (387.43, 218.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2023)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 250, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 757)
[M::mem_pestat] mean and std.dev: (275.60, 138.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 954)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (952, 1345, 1699)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3193)
[M::mem_pestat] mean and std.dev: (1041.57, 529.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3940)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (379, 767, 1451)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3595)
[M::mem_pestat] mean and std.dev: (869.61, 738.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4667)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695362 sequences (100000259 bp) in 3.192 CPU sec, 3.566 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 282548, 22, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 270, 521)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1245)
[M::mem_pestat] mean and std.dev: (353.04, 272.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1607)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 248, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 748)
[M::mem_pestat] mean and std.dev: (273.97, 137.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 942)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (272, 464, 2383)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6605)
[M::mem_pestat] mean and std.dev: (1573.86, 1790.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8736)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (276, 403, 1124)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2820)
[M::mem_pestat] mean and std.dev: (579.83, 480.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3668)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 694884 reads in 200.437 CPU sec, 6.482 real sec
[M::process] read 695180 sequences (100000135 bp) in 2.147 CPU sec, 2.171 real sec...
[M::mem_process_seqs] Processed 695194 reads in 142.681 CPU sec, 4.548 real sec
sorting block 42, #reads = 1074270 mem = 536882639 peak = 897064960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 282625, 23, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (283, 471, 742)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1660)
[M::mem_pestat] mean and std.dev: (443.03, 292.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2119)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 248, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 745)
[M::mem_pestat] mean and std.dev: (273.51, 136.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 938)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (432, 985, 2117)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5487)
[M::mem_pestat] mean and std.dev: (1180.17, 999.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7172)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 444, 736)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1812)
[M::mem_pestat] mean and std.dev: (428.46, 253.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2350)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695132 sequences (100000159 bp) in 2.916 CPU sec, 3.128 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23, 282739, 17, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 300, 660)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1656)
[M::mem_pestat] mean and std.dev: (445.27, 398.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2154)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 248, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 748)
[M::mem_pestat] mean and std.dev: (273.70, 136.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 942)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 998, 1938)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5404)
[M::mem_pestat] mean and std.dev: (1235.06, 1169.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7137)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 471, 1248)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3348)
[M::mem_pestat] mean and std.dev: (705.93, 644.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4398)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695308 sequences (100000146 bp) in 2.206 CPU sec, 2.211 real sec...
[M::mem_process_seqs] Processed 695362 reads in 201.660 CPU sec, 6.444 real sec
[M::mem_process_seqs] Processed 695180 reads in 138.673 CPU sec, 4.430 real sec
sorting block 43, #reads = 1073865 mem = 536878945 peak = 897064960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 282704, 25, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (261, 423, 624)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1350)
[M::mem_pestat] mean and std.dev: (450.06, 284.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1713)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 248, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 742)
[M::mem_pestat] mean and std.dev: (272.64, 135.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 934)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (92, 321, 675)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1841)
[M::mem_pestat] mean and std.dev: (353.82, 386.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2424)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (367, 629, 954)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2128)
[M::mem_pestat] mean and std.dev: (556.07, 329.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2715)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 44, #reads = 1074269 mem = 536878647 peak = 897064960
[M::process] read 695190 sequences (100000215 bp) in 3.267 CPU sec, 3.535 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 282793, 23, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 257, 979)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2501)
[M::mem_pestat] mean and std.dev: (455.37, 486.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3262)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 248, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 751)
[M::mem_pestat] mean and std.dev: (274.41, 137.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 946)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (333, 568, 1141)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2757)
[M::mem_pestat] mean and std.dev: (520.35, 384.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3565)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 333, 1113)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2933)
[M::mem_pestat] mean and std.dev: (539.04, 577.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3843)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695132 reads in 196.469 CPU sec, 6.289 real sec
[M::process] read 695374 sequences (100000032 bp) in 1.979 CPU sec, 1.985 real sec...
[M::mem_process_seqs] Processed 695308 reads in 135.075 CPU sec, 4.282 real sec
sorting block 45, #reads = 1074892 mem = 536878810 peak = 897064960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 283193, 18, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (234, 368, 963)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2421)
[M::mem_pestat] mean and std.dev: (549.49, 425.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3150)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 250, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 760)
[M::mem_pestat] mean and std.dev: (276.46, 139.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 958)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (287, 532, 766)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1724)
[M::mem_pestat] mean and std.dev: (544.71, 385.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2203)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (235, 309, 371)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 643)
[M::mem_pestat] mean and std.dev: (285.93, 103.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 779)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695454 sequences (100000176 bp) in 3.080 CPU sec, 3.324 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 283364, 32, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 313, 494)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1104)
[M::mem_pestat] mean and std.dev: (347.89, 212.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1409)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 249, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 766)
[M::mem_pestat] mean and std.dev: (276.72, 140.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 966)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (269, 909, 3527)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10043)
[M::mem_pestat] mean and std.dev: (1980.88, 2103.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13301)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 348, 808)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1974)
[M::mem_pestat] mean and std.dev: (451.31, 362.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2557)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696992 sequences (100000176 bp) in 2.001 CPU sec, 2.007 real sec...
[M::mem_process_seqs] Processed 695190 reads in 201.202 CPU sec, 6.612 real sec
[M::mem_process_seqs] Processed 695374 reads in 138.005 CPU sec, 4.401 real sec
sorting block 46, #reads = 1074689 mem = 536880621 peak = 897064960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 282953, 33, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 416, 1183)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3127)
[M::mem_pestat] mean and std.dev: (741.06, 686.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4099)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 250, 368)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 772)
[M::mem_pestat] mean and std.dev: (278.34, 142.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 974)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 1058, 2000)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5596)
[M::mem_pestat] mean and std.dev: (1201.73, 1048.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7394)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 344, 731)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1779)
[M::mem_pestat] mean and std.dev: (475.97, 380.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2303)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699134 sequences (100000035 bp) in 3.387 CPU sec, 3.808 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 283830, 15, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 269, 864)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2236)
[M::mem_pestat] mean and std.dev: (421.30, 376.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2922)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 244, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 748)
[M::mem_pestat] mean and std.dev: (271.79, 138.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 943)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (271, 1100, 2114)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5800)
[M::mem_pestat] mean and std.dev: (985.38, 780.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7643)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (358, 629, 991)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2257)
[M::mem_pestat] mean and std.dev: (616.72, 418.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2890)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695454 reads in 201.309 CPU sec, 6.438 real sec
[M::process] read 698390 sequences (100000032 bp) in 1.925 CPU sec, 1.951 real sec...
[M::mem_process_seqs] Processed 696992 reads in 138.721 CPU sec, 4.599 real sec
sorting block 47, #reads = 1074621 mem = 536878479 peak = 897064960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23, 284348, 25, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (292, 717, 935)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2221)
[M::mem_pestat] mean and std.dev: (546.68, 324.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2864)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 238, 351)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 735)
[M::mem_pestat] mean and std.dev: (265.70, 135.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 927)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (27, 424, 2690)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8016)
[M::mem_pestat] mean and std.dev: (912.17, 1170.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10679)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 271, 756)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1926)
[M::mem_pestat] mean and std.dev: (333.12, 252.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2511)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697592 sequences (100000087 bp) in 2.613 CPU sec, 3.016 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 284414, 17, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 439, 739)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1841)
[M::mem_pestat] mean and std.dev: (480.70, 414.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2392)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 241, 354)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 740)
[M::mem_pestat] mean and std.dev: (268.42, 136.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 933)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (643, 870, 2047)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4855)
[M::mem_pestat] mean and std.dev: (1063.19, 670.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6259)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 342, 522)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1112)
[M::mem_pestat] mean and std.dev: (347.43, 213.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1407)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697056 sequences (100000259 bp) in 2.004 CPU sec, 2.012 real sec...
[M::mem_process_seqs] Processed 699134 reads in 201.327 CPU sec, 6.655 real sec
sorting block 48, #reads = 1074728 mem = 536878754 peak = 897064960
[M::mem_process_seqs] Processed 698390 reads in 129.597 CPU sec, 4.198 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 283799, 18, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (128, 282, 826)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2222)
[M::mem_pestat] mean and std.dev: (376.68, 413.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2920)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 243, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 753)
[M::mem_pestat] mean and std.dev: (271.78, 138.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 950)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (136, 903, 1002)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2734)
[M::mem_pestat] mean and std.dev: (603.12, 445.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3600)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (243, 264, 467)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 915)
[M::mem_pestat] mean and std.dev: (302.67, 131.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1139)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 49, #reads = 1078851 mem = 536879346 peak = 897064960
[M::process] read 696452 sequences (100000074 bp) in 3.545 CPU sec, 3.779 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 283839, 23, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 271, 685)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1689)
[M::mem_pestat] mean and std.dev: (388.07, 302.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2191)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 246, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 755)
[M::mem_pestat] mean and std.dev: (272.89, 138.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 952)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 552, 972)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2504)
[M::mem_pestat] mean and std.dev: (500.70, 428.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3270)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 286, 1122)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3010)
[M::mem_pestat] mean and std.dev: (647.56, 711.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3954)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697592 reads in 195.804 CPU sec, 6.325 real sec
[M::process] read 696256 sequences (100000019 bp) in 2.163 CPU sec, 2.206 real sec...
[M::mem_process_seqs] Processed 697056 reads in 133.253 CPU sec, 4.394 real sec
sorting block 50, #reads = 1079229 mem = 536876406 peak = 897064960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (21, 283482, 18, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (235, 483, 1035)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2635)
[M::mem_pestat] mean and std.dev: (578.65, 441.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3435)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 247, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 752)
[M::mem_pestat] mean and std.dev: (272.89, 137.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 948)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 1607, 2106)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5910)
[M::mem_pestat] mean and std.dev: (1284.28, 849.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7812)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 327, 762)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1838)
[M::mem_pestat] mean and std.dev: (439.90, 379.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2376)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696412 sequences (100000269 bp) in 2.973 CPU sec, 3.180 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 283546, 13, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (260, 330, 780)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1820)
[M::mem_pestat] mean and std.dev: (452.27, 363.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2340)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 249, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 765)
[M::mem_pestat] mean and std.dev: (276.12, 140.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 965)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (434, 482, 935)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1937)
[M::mem_pestat] mean and std.dev: (468.92, 281.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2438)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 322, 714)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1742)
[M::mem_pestat] mean and std.dev: (410.87, 279.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2256)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695760 sequences (100000179 bp) in 1.969 CPU sec, 1.976 real sec...
[M::mem_process_seqs] Processed 696452 reads in 198.371 CPU sec, 6.516 real sec
[M::mem_process_seqs] Processed 696256 reads in 131.682 CPU sec, 4.196 real sec
sorting block 51, #reads = 1076573 mem = 536882158 peak = 897064960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 283770, 22, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 336, 1031)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2691)
[M::mem_pestat] mean and std.dev: (512.44, 490.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3521)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 249, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 768)
[M::mem_pestat] mean and std.dev: (276.59, 141.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 969)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 636, 1164)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3114)
[M::mem_pestat] mean and std.dev: (696.81, 692.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4089)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 450, 903)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2357)
[M::mem_pestat] mean and std.dev: (444.83, 373.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3084)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695596 sequences (100000017 bp) in 3.125 CPU sec, 3.364 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 283356, 24, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 442, 1274)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3388)
[M::mem_pestat] mean and std.dev: (700.26, 649.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4445)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 250, 369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 777)
[M::mem_pestat] mean and std.dev: (278.46, 141.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 981)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (142, 228, 434)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1018)
[M::mem_pestat] mean and std.dev: (246.00, 140.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1310)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 284, 1708)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4768)
[M::mem_pestat] mean and std.dev: (740.48, 865.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6298)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696412 reads in 188.819 CPU sec, 6.053 real sec
[M::process] read 695146 sequences (100000257 bp) in 2.117 CPU sec, 2.181 real sec...
sorting block 52, #reads = 1077721 mem = 536880466 peak = 897064960
[M::mem_process_seqs] Processed 695760 reads in 128.697 CPU sec, 4.083 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 283639, 30, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 387, 552)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1270)
[M::mem_pestat] mean and std.dev: (342.49, 235.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1629)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 252, 370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 778)
[M::mem_pestat] mean and std.dev: (279.70, 143.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 982)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (383, 546, 1211)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2867)
[M::mem_pestat] mean and std.dev: (658.56, 584.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3695)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (275, 585, 1133)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2849)
[M::mem_pestat] mean and std.dev: (714.80, 596.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3707)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 53, #reads = 1077742 mem = 536882631 peak = 897064960
[M::process] read 695136 sequences (100000276 bp) in 3.008 CPU sec, 3.258 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 282976, 19, 24)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 525, 1110)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3002)
[M::mem_pestat] mean and std.dev: (630.33, 470.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3948)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 253, 370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 778)
[M::mem_pestat] mean and std.dev: (279.49, 141.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 982)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (298, 835, 2280)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6244)
[M::mem_pestat] mean and std.dev: (1426.50, 1502.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8226)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 403, 509)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1103)
[M::mem_pestat] mean and std.dev: (384.45, 205.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1400)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695596 reads in 194.063 CPU sec, 6.399 real sec
[M::process] read 695012 sequences (100000200 bp) in 2.054 CPU sec, 2.082 real sec...
[M::mem_process_seqs] Processed 695146 reads in 129.037 CPU sec, 4.090 real sec
sorting block 54, #reads = 1077011 mem = 536878096 peak = 897064960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 283543, 23, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (444, 582, 1196)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2700)
[M::mem_pestat] mean and std.dev: (845.39, 606.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3452)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 252, 370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 776)
[M::mem_pestat] mean and std.dev: (279.21, 141.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 979)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (398, 1114, 1818)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4658)
[M::mem_pestat] mean and std.dev: (1032.55, 1104.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6078)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 792, 1157)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3077)
[M::mem_pestat] mean and std.dev: (733.00, 616.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4037)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 693944 sequences (100000027 bp) in 3.142 CPU sec, 3.408 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 282759, 28, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (238, 345, 1000)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2524)
[M::mem_pestat] mean and std.dev: (653.24, 725.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3555)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 252, 368)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 770)
[M::mem_pestat] mean and std.dev: (278.62, 140.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 971)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (572, 1365, 3237)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8567)
[M::mem_pestat] mean and std.dev: (1633.63, 1474.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11232)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 303, 1865)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5263)
[M::mem_pestat] mean and std.dev: (763.36, 867.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6962)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695136 reads in 195.018 CPU sec, 6.252 real sec
[M::process] read 694502 sequences (100000014 bp) in 2.172 CPU sec, 2.205 real sec...
[M::mem_process_seqs] Processed 695012 reads in 129.860 CPU sec, 4.275 real sec
sorting block 55, #reads = 1075417 mem = 536878940 peak = 897064960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 282325, 18, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (315, 501, 883)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2019)
[M::mem_pestat] mean and std.dev: (457.31, 258.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2587)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 254, 370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 772)
[M::mem_pestat] mean and std.dev: (280.45, 140.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 973)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (228, 528, 1127)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2925)
[M::mem_pestat] mean and std.dev: (547.20, 662.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3824)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 413, 1888)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5246)
[M::mem_pestat] mean and std.dev: (771.69, 989.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6925)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695510 sequences (100000030 bp) in 2.936 CPU sec, 3.142 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 282816, 20, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (136, 276, 709)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1855)
[M::mem_pestat] mean and std.dev: (381.50, 374.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2428)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 252, 369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 771)
[M::mem_pestat] mean and std.dev: (279.00, 140.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 972)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (289, 598, 1028)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2506)
[M::mem_pestat] mean and std.dev: (720.35, 629.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3245)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (258, 454, 1148)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2928)
[M::mem_pestat] mean and std.dev: (569.80, 583.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3818)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695660 sequences (100000110 bp) in 2.014 CPU sec, 2.020 real sec...
[M::mem_process_seqs] Processed 693944 reads in 198.944 CPU sec, 6.509 real sec
[M::mem_process_seqs] Processed 694502 reads in 131.285 CPU sec, 4.176 real sec
sorting block 56, #reads = 1075727 mem = 536879230 peak = 897064960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 283118, 22, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (256, 373, 1003)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2497)
[M::mem_pestat] mean and std.dev: (612.14, 561.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3244)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 247, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 747)
[M::mem_pestat] mean and std.dev: (272.78, 136.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 941)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (235, 642, 1391)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3703)
[M::mem_pestat] mean and std.dev: (836.38, 727.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4859)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (284, 367, 619)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1289)
[M::mem_pestat] mean and std.dev: (449.69, 297.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1640)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 57, #reads = 1075145 mem = 536878645 peak = 897064960
[M::process] read 695356 sequences (100000091 bp) in 3.009 CPU sec, 3.261 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 282880, 20, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 271, 596)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1482)
[M::mem_pestat] mean and std.dev: (387.45, 344.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1925)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 246, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 747)
[M::mem_pestat] mean and std.dev: (272.94, 136.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 941)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (121, 409, 1155)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3223)
[M::mem_pestat] mean and std.dev: (686.20, 756.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4257)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 416, 1219)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3253)
[M::mem_pestat] mean and std.dev: (716.41, 640.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4270)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695324 sequences (100000138 bp) in 2.020 CPU sec, 2.025 real sec...
[M::mem_process_seqs] Processed 695510 reads in 197.852 CPU sec, 6.380 real sec
[M::mem_process_seqs] Processed 695660 reads in 130.882 CPU sec, 4.220 real sec
sorting block 58, #reads = 1075527 mem = 536881405 peak = 897064960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 282637, 29, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (135, 496, 934)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2532)
[M::mem_pestat] mean and std.dev: (578.51, 571.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3331)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 247, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 744)
[M::mem_pestat] mean and std.dev: (272.63, 136.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 937)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 734, 1099)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2981)
[M::mem_pestat] mean and std.dev: (691.31, 556.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3922)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 842, 1410)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3780)
[M::mem_pestat] mean and std.dev: (830.10, 671.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4965)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695474 sequences (100000084 bp) in 2.912 CPU sec, 3.125 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 283402, 23, 18)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 280, 968)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2558)
[M::mem_pestat] mean and std.dev: (554.31, 567.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3353)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 247, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 747)
[M::mem_pestat] mean and std.dev: (273.13, 136.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 941)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 423, 1733)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4879)
[M::mem_pestat] mean and std.dev: (910.22, 944.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6452)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 367, 392)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 820)
[M::mem_pestat] mean and std.dev: (312.00, 156.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1034)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695804 sequences (100000161 bp) in 2.079 CPU sec, 2.085 real sec...
[M::mem_process_seqs] Processed 695356 reads in 199.843 CPU sec, 6.442 real sec
sorting block 59, #reads = 1075525 mem = 536877869 peak = 897064960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 282893, 33, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (140, 322, 832)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2216)
[M::mem_pestat] mean and std.dev: (461.86, 433.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2908)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 247, 357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 741)
[M::mem_pestat] mean and std.dev: (271.42, 134.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 933)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 683, 1759)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4849)
[M::mem_pestat] mean and std.dev: (947.50, 977.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6394)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 317, 561)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1259)
[M::mem_pestat] mean and std.dev: (342.16, 255.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1608)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695274 sequences (100000235 bp) in 2.319 CPU sec, 2.323 real sec...
[M::mem_process_seqs] Processed 695474 reads in 114.261 CPU sec, 3.713 real sec
[M::mem_process_seqs] Processed 695324 reads in 294.813 CPU sec, 9.490 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 283662, 31, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 318, 972)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2608)
[M::mem_pestat] mean and std.dev: (486.09, 521.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3426)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 246, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 746)
[M::mem_pestat] mean and std.dev: (272.30, 136.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 940)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 620, 1747)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4807)
[M::mem_pestat] mean and std.dev: (801.07, 831.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6337)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 348, 1584)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4386)
[M::mem_pestat] mean and std.dev: (697.22, 886.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5787)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 60, #reads = 1074952 mem = 536878399 peak = 897064960
[M::process] read 695694 sequences (100000020 bp) in 3.090 CPU sec, 3.449 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 283142, 25, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 319, 551)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1297)
[M::mem_pestat] mean and std.dev: (370.41, 256.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1670)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 248, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 756)
[M::mem_pestat] mean and std.dev: (274.78, 138.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 953)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (338, 436, 1235)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3029)
[M::mem_pestat] mean and std.dev: (666.46, 506.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3926)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 376, 1163)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3055)
[M::mem_pestat] mean and std.dev: (702.96, 635.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4001)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695804 reads in 216.590 CPU sec, 6.915 real sec
[M::mem_process_seqs] Processed 695274 reads in 132.750 CPU sec, 4.218 real sec
[M::process] read 695734 sequences (100000260 bp) in 2.493 CPU sec, 2.638 real sec...
sorting block 61, #reads = 1075907 mem = 536884232 peak = 897064960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 283632, 27, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 312, 882)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2226)
[M::mem_pestat] mean and std.dev: (579.15, 552.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2898)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 247, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 747)
[M::mem_pestat] mean and std.dev: (273.05, 136.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 941)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (248, 684, 1643)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4433)
[M::mem_pestat] mean and std.dev: (1032.85, 1211.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5879)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 322, 1158)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3084)
[M::mem_pestat] mean and std.dev: (595.63, 499.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4047)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694214 sequences (100000245 bp) in 3.695 CPU sec, 4.108 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 283557, 24, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 394, 651)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1557)
[M::mem_pestat] mean and std.dev: (457.73, 365.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2010)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 248, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 759)
[M::mem_pestat] mean and std.dev: (274.88, 138.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 957)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (229, 970, 2458)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6916)
[M::mem_pestat] mean and std.dev: (1195.42, 1204.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9145)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 275, 788)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1914)
[M::mem_pestat] mean and std.dev: (379.73, 291.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2477)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695694 reads in 195.182 CPU sec, 6.260 real sec
[M::mem_process_seqs] Processed 695734 reads in 130.457 CPU sec, 4.154 real sec
sorting block 62, #reads = 1075950 mem = 536877107 peak = 897064960
[M::process] read 695874 sequences (100000132 bp) in 2.813 CPU sec, 3.066 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 282625, 27, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (293, 592, 1350)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3464)
[M::mem_pestat] mean and std.dev: (616.05, 577.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4521)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 254, 371)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 777)
[M::mem_pestat] mean and std.dev: (281.11, 142.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 980)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (82, 185, 553)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1495)
[M::mem_pestat] mean and std.dev: (294.42, 290.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1966)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (278, 406, 523)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1013)
[M::mem_pestat] mean and std.dev: (404.60, 169.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1258)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703058 sequences (100000019 bp) in 2.956 CPU sec, 3.219 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 283054, 13, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 236, 428)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 958)
[M::mem_pestat] mean and std.dev: (281.63, 184.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1223)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 248, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 759)
[M::mem_pestat] mean and std.dev: (275.28, 139.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 957)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (66, 574, 2021)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5931)
[M::mem_pestat] mean and std.dev: (915.38, 829.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7886)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 332, 871)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2323)
[M::mem_pestat] mean and std.dev: (565.44, 590.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3049)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 694214 reads in 201.351 CPU sec, 6.476 real sec
sorting block 63, #reads = 1076861 mem = 536878672 peak = 897064960
[M::mem_process_seqs] Processed 695874 reads in 138.274 CPU sec, 4.383 real sec
[M::process] read 703494 sequences (100000200 bp) in 2.956 CPU sec, 3.160 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 286100, 22, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 386, 718)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1784)
[M::mem_pestat] mean and std.dev: (447.21, 329.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2317)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 225, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 696)
[M::mem_pestat] mean and std.dev: (254.52, 130.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 877)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (109, 518, 801)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2185)
[M::mem_pestat] mean and std.dev: (514.50, 424.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2877)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 229, 431)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 941)
[M::mem_pestat] mean and std.dev: (279.37, 165.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1196)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 64, #reads = 1075109 mem = 536879520 peak = 897064960
[M::process] read 701892 sequences (100000110 bp) in 3.354 CPU sec, 3.807 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 286136, 19, 24)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 318, 1096)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2930)
[M::mem_pestat] mean and std.dev: (609.25, 623.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3847)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 223, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 689)
[M::mem_pestat] mean and std.dev: (252.63, 129.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 868)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (438, 540, 2505)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6639)
[M::mem_pestat] mean and std.dev: (1152.79, 1155.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8706)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 302, 395)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 825)
[M::mem_pestat] mean and std.dev: (276.81, 152.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1040)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703058 reads in 213.872 CPU sec, 6.859 real sec
[M::mem_process_seqs] Processed 703494 reads in 144.652 CPU sec, 4.606 real sec
[M::process] read 701206 sequences (100000166 bp) in 2.548 CPU sec, 2.725 real sec...
sorting block 65, #reads = 1076065 mem = 536880320 peak = 897064960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20, 286115, 28, 23)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 282, 1387)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3799)
[M::mem_pestat] mean and std.dev: (582.63, 684.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5005)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 228, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 709)
[M::mem_pestat] mean and std.dev: (257.71, 132.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 894)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (123, 407, 2220)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6414)
[M::mem_pestat] mean and std.dev: (1142.19, 1476.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8511)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 222, 482)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1052)
[M::mem_pestat] mean and std.dev: (312.48, 207.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1337)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699716 sequences (100000040 bp) in 3.171 CPU sec, 3.474 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 286069, 21, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (413, 653, 1426)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3452)
[M::mem_pestat] mean and std.dev: (732.27, 499.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4465)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 231, 345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 723)
[M::mem_pestat] mean and std.dev: (261.36, 135.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 912)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (549, 1339, 2018)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4956)
[M::mem_pestat] mean and std.dev: (1260.76, 816.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6425)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (292, 390, 1987)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5377)
[M::mem_pestat] mean and std.dev: (1264.38, 1481.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7191)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701892 reads in 212.061 CPU sec, 6.827 real sec
[M::mem_process_seqs] Processed 701206 reads in 141.348 CPU sec, 4.494 real sec
[M::process] read 699216 sequences (100000277 bp) in 2.234 CPU sec, 2.319 real sec...
sorting block 66, #reads = 1076697 mem = 536880199 peak = 897064960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 285204, 30, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (263, 482, 1759)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4751)
[M::mem_pestat] mean and std.dev: (942.00, 1057.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6247)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 236, 351)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 737)
[M::mem_pestat] mean and std.dev: (266.13, 137.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 930)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (66, 232, 609)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1695)
[M::mem_pestat] mean and std.dev: (287.40, 305.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2238)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (241, 395, 1039)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2635)
[M::mem_pestat] mean and std.dev: (540.42, 451.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3433)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697736 sequences (100000140 bp) in 3.573 CPU sec, 3.874 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 284828, 11, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (232, 587, 751)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1789)
[M::mem_pestat] mean and std.dev: (503.26, 265.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2308)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 238, 356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 750)
[M::mem_pestat] mean and std.dev: (269.18, 139.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 947)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1447, 1664, 2079)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (183, 3343)
[M::mem_pestat] mean and std.dev: (1622.20, 634.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4161)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 492, 969)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2513)
[M::mem_pestat] mean and std.dev: (481.22, 392.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3285)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699716 reads in 208.031 CPU sec, 6.639 real sec
[M::process] read 698016 sequences (100000104 bp) in 2.268 CPU sec, 2.298 real sec...
sorting block 67, #reads = 1075901 mem = 536877529 peak = 897064960
[M::mem_process_seqs] Processed 699216 reads in 138.079 CPU sec, 4.548 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 283899, 19, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (241, 420, 751)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1771)
[M::mem_pestat] mean and std.dev: (411.00, 241.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2281)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 242, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 767)
[M::mem_pestat] mean and std.dev: (273.39, 142.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 969)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (862, 1420, 2282)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5122)
[M::mem_pestat] mean and std.dev: (1545.50, 935.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6542)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 359, 955)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2421)
[M::mem_pestat] mean and std.dev: (603.96, 574.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3154)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 68, #reads = 1076491 mem = 536876835 peak = 897064960
[M::process] read 698154 sequences (100000010 bp) in 3.013 CPU sec, 3.391 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 284520, 20, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 419, 835)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2187)
[M::mem_pestat] mean and std.dev: (503.72, 462.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2863)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 242, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 770)
[M::mem_pestat] mean and std.dev: (273.97, 142.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 973)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (722, 1237, 2162)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5042)
[M::mem_pestat] mean and std.dev: (1371.65, 1043.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6482)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (322, 515, 1270)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3166)
[M::mem_pestat] mean and std.dev: (748.36, 620.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4114)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697904 sequences (100000280 bp) in 2.150 CPU sec, 2.147 real sec...
[M::mem_process_seqs] Processed 697736 reads in 207.360 CPU sec, 6.841 real sec
[M::mem_process_seqs] Processed 698016 reads in 140.878 CPU sec, 4.485 real sec
sorting block 69, #reads = 1075503 mem = 536878136 peak = 897064960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 284977, 12, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 472, 1898)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5262)
[M::mem_pestat] mean and std.dev: (1158.37, 1269.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6944)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 242, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 764)
[M::mem_pestat] mean and std.dev: (273.24, 141.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 965)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 801, 1326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3680)
[M::mem_pestat] mean and std.dev: (665.82, 745.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4857)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (277, 433, 1225)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3121)
[M::mem_pestat] mean and std.dev: (713.07, 597.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4069)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697540 sequences (100000212 bp) in 3.160 CPU sec, 3.368 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 284326, 28, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 370, 669)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1635)
[M::mem_pestat] mean and std.dev: (379.72, 309.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2118)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 242, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 758)
[M::mem_pestat] mean and std.dev: (271.87, 139.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 957)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (266, 514, 974)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2390)
[M::mem_pestat] mean and std.dev: (486.71, 383.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3098)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 346, 828)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2118)
[M::mem_pestat] mean and std.dev: (472.06, 420.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2763)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697626 sequences (100000014 bp) in 2.165 CPU sec, 2.183 real sec...
[M::mem_process_seqs] Processed 698154 reads in 219.733 CPU sec, 7.048 real sec
[M::mem_process_seqs] Processed 697904 reads in 149.531 CPU sec, 4.811 real sec
sorting block 70, #reads = 1075112 mem = 536879878 peak = 897064960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 284462, 24, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 291, 555)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1315)
[M::mem_pestat] mean and std.dev: (308.68, 237.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1695)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 242, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 762)
[M::mem_pestat] mean and std.dev: (272.88, 140.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 962)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (116, 538, 1388)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3932)
[M::mem_pestat] mean and std.dev: (1018.12, 1201.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5824)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 266, 617)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1425)
[M::mem_pestat] mean and std.dev: (299.80, 231.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1829)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698120 sequences (100000173 bp) in 3.436 CPU sec, 3.738 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 284576, 19, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 483, 1076)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2866)
[M::mem_pestat] mean and std.dev: (599.57, 573.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3761)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 243, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 762)
[M::mem_pestat] mean and std.dev: (273.31, 140.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 962)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (272, 831, 2639)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7373)
[M::mem_pestat] mean and std.dev: (923.56, 965.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9740)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 265, 510)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1160)
[M::mem_pestat] mean and std.dev: (311.65, 208.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1485)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696706 sequences (100000073 bp) in 2.180 CPU sec, 2.186 real sec...
[M::mem_process_seqs] Processed 697540 reads in 212.656 CPU sec, 6.838 real sec
[M::mem_process_seqs] Processed 697626 reads in 138.895 CPU sec, 4.403 real sec
sorting block 71, #reads = 1071887 mem = 536879019 peak = 897064960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 284456, 24, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 231, 869)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2279)
[M::mem_pestat] mean and std.dev: (377.11, 404.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2984)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 239, 356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 746)
[M::mem_pestat] mean and std.dev: (269.57, 138.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 941)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 448, 787)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2019)
[M::mem_pestat] mean and std.dev: (411.38, 358.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2635)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (241, 281, 533)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1117)
[M::mem_pestat] mean and std.dev: (327.16, 190.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1409)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 72, #reads = 1074657 mem = 536877593 peak = 897064960
[M::process] read 696814 sequences (100000249 bp) in 2.767 CPU sec, 3.247 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 283375, 29, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (379, 507, 1159)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2719)
[M::mem_pestat] mean and std.dev: (635.17, 473.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3499)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 244, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 760)
[M::mem_pestat] mean and std.dev: (273.96, 140.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 959)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 378, 775)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2013)
[M::mem_pestat] mean and std.dev: (499.18, 426.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2632)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 328, 757)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1829)
[M::mem_pestat] mean and std.dev: (487.67, 429.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2365)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696096 sequences (100000017 bp) in 2.013 CPU sec, 2.020 real sec...
[M::mem_process_seqs] Processed 698120 reads in 212.205 CPU sec, 6.857 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 283229, 25, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 367, 945)
[M::process] read 696254 sequences (100000266 bp) in 2.313 CPU sec, 2.315 real sec...
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2499)
[M::mem_pestat] mean and std.dev: (585.55, 570.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3276)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 244, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 762)
[M::mem_pestat] mean and std.dev: (273.79, 140.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 962)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (626, 1437, 3310)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8678)
[M::mem_pestat] mean and std.dev: (2225.32, 2252.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11362)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (236, 582, 1172)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3044)
[M::mem_pestat] mean and std.dev: (725.12, 723.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3980)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696814 reads in 123.809 CPU sec, 4.022 real sec
sorting block 73, #reads = 1074118 mem = 536878166 peak = 897064960
[M::mem_process_seqs] Processed 696706 reads in 306.910 CPU sec, 9.891 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 283251, 28, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 285, 431)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 933)
[M::mem_pestat] mean and std.dev: (310.86, 198.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1184)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 246, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 770)
[M::mem_pestat] mean and std.dev: (276.46, 141.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 972)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (538, 1476, 2065)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5119)
[M::mem_pestat] mean and std.dev: (1244.08, 902.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6646)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 560, 1075)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2781)
[M::mem_pestat] mean and std.dev: (734.67, 633.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3634)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 74, #reads = 1071941 mem = 536881546 peak = 897064960
[M::process] read 696166 sequences (100000081 bp) in 2.872 CPU sec, 3.250 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 282826, 28, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (265, 565, 3259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9247)
[M::mem_pestat] mean and std.dev: (1444.34, 1416.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12241)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 244, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 755)
[M::mem_pestat] mean and std.dev: (274.25, 140.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 952)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 421, 1311)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3517)
[M::mem_pestat] mean and std.dev: (809.54, 977.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4720)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 352, 551)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1277)
[M::mem_pestat] mean and std.dev: (375.57, 278.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1640)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695400 sequences (100000262 bp) in 2.165 CPU sec, 2.168 real sec...
[M::mem_process_seqs] Processed 696096 reads in 242.187 CPU sec, 7.727 real sec
[M::mem_process_seqs] Processed 696254 reads in 148.636 CPU sec, 4.922 real sec
sorting block 75, #reads = 1072197 mem = 536881549 peak = 897064960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 283458, 23, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 206, 673)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1709)
[M::mem_pestat] mean and std.dev: (296.14, 218.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2227)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 245, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 761)
[M::mem_pestat] mean and std.dev: (274.47, 140.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 960)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (399, 789, 1835)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4707)
[M::mem_pestat] mean and std.dev: (1053.05, 876.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6143)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 362, 1421)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3887)
[M::mem_pestat] mean and std.dev: (789.32, 929.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5120)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695816 sequences (100000228 bp) in 3.009 CPU sec, 3.410 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 282847, 26, 22)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 420, 985)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2579)
[M::mem_pestat] mean and std.dev: (602.34, 671.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3376)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 249, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 769)
[M::mem_pestat] mean and std.dev: (278.30, 142.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 970)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (270, 752, 2194)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6042)
[M::mem_pestat] mean and std.dev: (1492.08, 1706.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8320)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 273, 436)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 962)
[M::mem_pestat] mean and std.dev: (321.91, 171.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1225)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695180 sequences (100000135 bp) in 2.272 CPU sec, 2.277 real sec...
[M::mem_process_seqs] Processed 696166 reads in 221.104 CPU sec, 7.268 real sec
[M::mem_process_seqs] Processed 695400 reads in 146.190 CPU sec, 4.699 real sec
sorting block 76, #reads = 1071089 mem = 536876352 peak = 897064960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 283334, 26, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (269, 400, 754)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1724)
[M::mem_pestat] mean and std.dev: (510.14, 407.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2209)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 247, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 768)
[M::mem_pestat] mean and std.dev: (277.03, 142.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 969)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (421, 1206, 1758)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4432)
[M::mem_pestat] mean and std.dev: (1214.31, 912.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5769)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (231, 302, 583)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1287)
[M::mem_pestat] mean and std.dev: (399.12, 274.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1639)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695460 sequences (100000112 bp) in 2.932 CPU sec, 3.195 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 283040, 13, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (235, 611, 1873)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5149)
[M::mem_pestat] mean and std.dev: (1442.65, 1631.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7970)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 249, 370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 778)
[M::mem_pestat] mean and std.dev: (279.49, 143.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 982)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (57, 376, 1211)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3519)
[M::mem_pestat] mean and std.dev: (611.42, 728.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4673)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 292, 992)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2578)
[M::mem_pestat] mean and std.dev: (515.02, 468.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3371)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706788 sequences (100000162 bp) in 2.152 CPU sec, 2.153 real sec...
[M::mem_process_seqs] Processed 695816 reads in 217.038 CPU sec, 6.991 real sec
[M::mem_process_seqs] Processed 695180 reads in 142.458 CPU sec, 4.605 real sec
sorting block 77, #reads = 1070466 mem = 536877624 peak = 897064960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 282731, 19, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 353, 603)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1377)
[M::mem_pestat] mean and std.dev: (374.24, 241.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1764)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 249, 368)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 774)
[M::mem_pestat] mean and std.dev: (278.25, 143.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 977)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (143, 818, 4677)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13745)
[M::mem_pestat] mean and std.dev: (2256.37, 3018.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 18279)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 435, 806)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1994)
[M::mem_pestat] mean and std.dev: (498.10, 421.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2588)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705280 sequences (100000216 bp) in 3.099 CPU sec, 3.523 real sec...
sorting block 78, #reads = 1071449 mem = 536883480 peak = 897064960
[M::process] read 703620 sequences (100000119 bp) in 2.175 CPU sec, 2.183 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 286885, 22, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (280, 711, 902)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2146)
[M::mem_pestat] mean and std.dev: (631.79, 404.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2768)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 214, 316)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 652)
[M::mem_pestat] mean and std.dev: (242.24, 122.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 820)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 474, 970)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2592)
[M::mem_pestat] mean and std.dev: (514.84, 511.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3403)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (248, 495, 1213)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3143)
[M::mem_pestat] mean and std.dev: (623.33, 481.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4108)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695460 reads in 236.925 CPU sec, 7.672 real sec
[M::mem_process_seqs] Processed 706788 reads in 163.289 CPU sec, 5.202 real sec
sorting block 79, #reads = 1069171 mem = 536883337 peak = 897064960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 286825, 18, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (139, 305, 595)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1507)
[M::mem_pestat] mean and std.dev: (369.39, 294.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1963)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 219, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 672)
[M::mem_pestat] mean and std.dev: (247.48, 125.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 846)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (404, 703, 1396)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3380)
[M::mem_pestat] mean and std.dev: (876.94, 649.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4372)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 1014, 1305)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3481)
[M::mem_pestat] mean and std.dev: (812.00, 622.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4569)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703228 sequences (100000295 bp) in 2.663 CPU sec, 2.964 real sec...
[M::process] read 703420 sequences (100000220 bp) in 2.193 CPU sec, 2.202 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 286480, 30, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (228, 384, 2203)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6153)
[M::mem_pestat] mean and std.dev: (833.00, 911.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8128)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 224, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 692)
[M::mem_pestat] mean and std.dev: (252.86, 128.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 872)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (257, 896, 1392)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3662)
[M::mem_pestat] mean and std.dev: (837.21, 693.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4797)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 340, 849)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2107)
[M::mem_pestat] mean and std.dev: (545.63, 539.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2736)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 705280 reads in 234.137 CPU sec, 7.517 real sec
[M::mem_process_seqs] Processed 703620 reads in 157.572 CPU sec, 5.285 real sec
sorting block 80, #reads = 1072382 mem = 536877529 peak = 897064960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 286022, 13, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 384, 428)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 934)
[M::mem_pestat] mean and std.dev: (280.97, 121.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1187)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 226, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 696)
[M::mem_pestat] mean and std.dev: (253.72, 128.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 877)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 1193, 2666)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7652)
[M::mem_pestat] mean and std.dev: (1265.62, 1230.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10145)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (245, 535, 1003)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2519)
[M::mem_pestat] mean and std.dev: (688.97, 562.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3277)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701754 sequences (100000182 bp) in 3.501 CPU sec, 3.742 real sec...
[M::process] read 700784 sequences (100000064 bp) in 2.143 CPU sec, 2.148 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 286940, 30, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 307, 1024)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2650)
[M::mem_pestat] mean and std.dev: (493.37, 384.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3463)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 226, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 696)
[M::mem_pestat] mean and std.dev: (253.66, 128.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 877)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (388, 775, 2434)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6526)
[M::mem_pestat] mean and std.dev: (850.29, 742.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8572)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (363, 552, 1292)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3150)
[M::mem_pestat] mean and std.dev: (618.67, 412.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4079)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703228 reads in 240.914 CPU sec, 7.958 real sec
[M::mem_process_seqs] Processed 703420 reads in 162.442 CPU sec, 5.196 real sec
sorting block 81, #reads = 1071795 mem = 536887033 peak = 897064960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 285700, 20, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (251, 540, 775)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1823)
[M::mem_pestat] mean and std.dev: (457.91, 269.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2347)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 229, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 710)
[M::mem_pestat] mean and std.dev: (257.90, 130.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 895)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 468, 1056)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2778)
[M::mem_pestat] mean and std.dev: (410.29, 366.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3639)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 406, 818)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1966)
[M::mem_pestat] mean and std.dev: (547.03, 412.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2540)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700508 sequences (100000267 bp) in 3.263 CPU sec, 3.505 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 285856, 27, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (251, 449, 901)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2201)
[M::mem_pestat] mean and std.dev: (629.74, 603.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3045)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 233, 345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 721)
[M::mem_pestat] mean and std.dev: (261.72, 133.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 909)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (370, 544, 1177)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2791)
[M::mem_pestat] mean and std.dev: (524.82, 351.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3598)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (268, 362, 631)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1357)
[M::mem_pestat] mean and std.dev: (443.78, 251.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1720)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699664 sequences (100000283 bp) in 2.204 CPU sec, 2.207 real sec...
[M::mem_process_seqs] Processed 701754 reads in 225.102 CPU sec, 7.183 real sec
sorting block 82, #reads = 1069557 mem = 536877817 peak = 897064960
[M::mem_process_seqs] Processed 700784 reads in 149.454 CPU sec, 4.758 real sec
sorting block 83, #reads = 1071153 mem = 536878144 peak = 897064960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 285181, 17, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (135, 430, 1263)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3519)
[M::mem_pestat] mean and std.dev: (762.75, 931.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4647)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 233, 346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 724)
[M::mem_pestat] mean and std.dev: (262.61, 134.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 913)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (374, 677, 1758)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4526)
[M::mem_pestat] mean and std.dev: (921.06, 761.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5910)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (253, 611, 748)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1738)
[M::mem_pestat] mean and std.dev: (492.30, 356.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2233)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699164 sequences (100000239 bp) in 3.034 CPU sec, 3.343 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 284769, 15, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 393, 1786)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4944)
[M::mem_pestat] mean and std.dev: (1089.58, 1258.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6523)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 236, 349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 731)
[M::mem_pestat] mean and std.dev: (264.50, 134.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 922)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (357, 481, 1460)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3666)
[M::mem_pestat] mean and std.dev: (846.20, 746.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4769)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 263, 965)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2533)
[M::mem_pestat] mean and std.dev: (550.05, 555.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3317)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699760 sequences (100000168 bp) in 2.163 CPU sec, 2.270 real sec...
[M::mem_process_seqs] Processed 700508 reads in 229.700 CPU sec, 7.636 real sec
[M::mem_process_seqs] Processed 699664 reads in 147.846 CPU sec, 4.783 real sec
sorting block 84, #reads = 1071410 mem = 536883153 peak = 897064960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 284787, 17, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 312, 806)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2068)
[M::mem_pestat] mean and std.dev: (418.02, 308.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2699)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 237, 352)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 738)
[M::mem_pestat] mean and std.dev: (266.25, 135.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 931)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (386, 621, 965)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2123)
[M::mem_pestat] mean and std.dev: (612.65, 405.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2702)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (289, 468, 1055)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2587)
[M::mem_pestat] mean and std.dev: (577.66, 492.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3353)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698618 sequences (100000167 bp) in 2.973 CPU sec, 3.387 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 284959, 18, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 272, 798)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2066)
[M::mem_pestat] mean and std.dev: (474.11, 482.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2700)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 234, 347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 725)
[M::mem_pestat] mean and std.dev: (263.35, 134.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 914)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (248, 559, 1016)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2552)
[M::mem_pestat] mean and std.dev: (587.18, 449.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3320)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 390, 1225)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3259)
[M::mem_pestat] mean and std.dev: (644.50, 593.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4276)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697446 sequences (100000293 bp) in 2.103 CPU sec, 2.105 real sec...
[M::mem_process_seqs] Processed 699164 reads in 225.672 CPU sec, 7.337 real sec
[M::mem_process_seqs] Processed 699760 reads in 150.453 CPU sec, 4.841 real sec
sorting block 85, #reads = 1071633 mem = 536884742 peak = 897064960
[M::process] read 699172 sequences (100000025 bp) in 3.189 CPU sec, 3.546 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 284126, 37, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 453, 666)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1558)
[M::mem_pestat] mean and std.dev: (458.54, 280.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2004)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 242, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 756)
[M::mem_pestat] mean and std.dev: (272.13, 139.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 954)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (378, 796, 1434)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3546)
[M::mem_pestat] mean and std.dev: (790.09, 686.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4602)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (382, 486, 1156)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2704)
[M::mem_pestat] mean and std.dev: (763.44, 632.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3478)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696864 sequences (100000045 bp) in 2.435 CPU sec, 2.445 real sec...
[M::mem_process_seqs] Processed 697446 reads in 123.860 CPU sec, 3.923 real sec
sorting block 86, #reads = 1070957 mem = 536879551 peak = 897064960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 284838, 39, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 293, 835)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2107)
[M::mem_pestat] mean and std.dev: (482.43, 406.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2743)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 238, 353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 739)
[M::mem_pestat] mean and std.dev: (267.36, 136.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 932)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (399, 658, 1013)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2241)
[M::mem_pestat] mean and std.dev: (679.36, 487.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2855)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 303, 637)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1551)
[M::mem_pestat] mean and std.dev: (376.47, 321.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2008)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 284152, 15, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (264, 353, 658)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1446)
[M::mem_pestat] mean and std.dev: (481.97, 339.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1840)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 235, 350)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 734)
[M::mem_pestat] mean and std.dev: (265.53, 136.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 926)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (100, 832, 1988)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5764)
[M::mem_pestat] mean and std.dev: (1300.40, 1551.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7652)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (271, 341, 736)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1666)
[M::mem_pestat] mean and std.dev: (404.23, 277.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2131)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698618 reads in 333.064 CPU sec, 10.674 real sec
[M::process] read 696792 sequences (100000037 bp) in 2.445 CPU sec, 2.464 real sec...
[M::mem_process_seqs] Processed 699172 reads in 169.359 CPU sec, 5.648 real sec
sorting block 87, #reads = 1072683 mem = 536879945 peak = 897064960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 284076, 17, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (235, 322, 1053)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2689)
[M::mem_pestat] mean and std.dev: (635.46, 579.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3507)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 244, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 763)
[M::mem_pestat] mean and std.dev: (274.72, 142.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 963)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 473, 1563)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4343)
[M::mem_pestat] mean and std.dev: (524.21, 495.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5733)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 541, 1255)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3347)
[M::mem_pestat] mean and std.dev: (671.60, 635.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4393)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696848 sequences (100000283 bp) in 2.964 CPU sec, 3.388 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 283868, 28, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 442, 927)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2373)
[M::mem_pestat] mean and std.dev: (455.03, 347.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3096)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 244, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 769)
[M::mem_pestat] mean and std.dev: (275.75, 143.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 971)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (404, 598, 1356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3260)
[M::mem_pestat] mean and std.dev: (758.27, 663.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4212)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (231, 266, 479)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 975)
[M::mem_pestat] mean and std.dev: (301.72, 114.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1223)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695636 sequences (100000079 bp) in 2.103 CPU sec, 2.219 real sec...
[M::mem_process_seqs] Processed 696864 reads in 215.089 CPU sec, 7.152 real sec
sorting block 88, #reads = 1071691 mem = 536882160 peak = 897064960
[M::mem_process_seqs] Processed 696792 reads in 142.796 CPU sec, 4.565 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 283453, 27, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 403, 756)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1920)
[M::mem_pestat] mean and std.dev: (475.59, 380.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2502)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 244, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 777)
[M::mem_pestat] mean and std.dev: (277.37, 145.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 982)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (409, 580, 1492)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3658)
[M::mem_pestat] mean and std.dev: (807.52, 832.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4741)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 329, 556)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1232)
[M::mem_pestat] mean and std.dev: (343.35, 230.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1570)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 89, #reads = 1072256 mem = 536876811 peak = 897064960
[M::process] read 695586 sequences (100000126 bp) in 2.931 CPU sec, 3.244 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 283177, 43, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (232, 432, 1678)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4570)
[M::mem_pestat] mean and std.dev: (758.62, 890.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6016)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 248, 370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 780)
[M::mem_pestat] mean and std.dev: (279.38, 144.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 985)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (388, 802, 1677)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4255)
[M::mem_pestat] mean and std.dev: (1096.38, 940.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5544)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (240, 349, 605)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1335)
[M::mem_pestat] mean and std.dev: (409.59, 285.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1700)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695686 sequences (100000143 bp) in 2.195 CPU sec, 2.198 real sec...
[M::mem_process_seqs] Processed 696848 reads in 213.608 CPU sec, 6.893 real sec
[M::mem_process_seqs] Processed 695636 reads in 142.593 CPU sec, 4.552 real sec
sorting block 90, #reads = 1072071 mem = 536877954 peak = 897064960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 282454, 27, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (225, 457, 847)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2091)
[M::mem_pestat] mean and std.dev: (438.12, 299.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2713)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 248, 371)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 783)
[M::mem_pestat] mean and std.dev: (280.09, 146.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 989)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (126, 439, 869)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2355)
[M::mem_pestat] mean and std.dev: (403.78, 330.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3098)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 198, 687)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1737)
[M::mem_pestat] mean and std.dev: (376.35, 396.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2262)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702176 sequences (100000083 bp) in 2.781 CPU sec, 3.177 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 283639, 27, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (238, 509, 1622)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4390)
[M::mem_pestat] mean and std.dev: (888.62, 906.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5774)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 249, 372)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 786)
[M::mem_pestat] mean and std.dev: (279.96, 145.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 993)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (294, 564, 1349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3459)
[M::mem_pestat] mean and std.dev: (851.44, 869.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4514)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 458, 770)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1898)
[M::mem_pestat] mean and std.dev: (472.82, 401.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2462)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702480 sequences (100000195 bp) in 2.044 CPU sec, 2.053 real sec...
[M::mem_process_seqs] Processed 695586 reads in 228.185 CPU sec, 7.433 real sec
[M::mem_process_seqs] Processed 695686 reads in 155.675 CPU sec, 5.066 real sec
sorting block 91, #reads = 1068533 mem = 536879551 peak = 897064960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 285142, 30, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 225, 793)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2075)
[M::mem_pestat] mean and std.dev: (387.39, 345.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2716)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 228, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 709)
[M::mem_pestat] mean and std.dev: (257.81, 132.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 894)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (264, 621, 1113)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2811)
[M::mem_pestat] mean and std.dev: (571.21, 504.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3660)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (234, 271, 610)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1362)
[M::mem_pestat] mean and std.dev: (318.50, 183.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1738)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700784 sequences (100000132 bp) in 3.328 CPU sec, 3.729 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20, 286214, 27, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (250, 734, 2476)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6928)
[M::mem_pestat] mean and std.dev: (813.06, 839.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9154)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 228, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 706)
[M::mem_pestat] mean and std.dev: (256.79, 131.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 890)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 546, 770)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1936)
[M::mem_pestat] mean and std.dev: (387.00, 282.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2519)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (304, 357, 910)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2122)
[M::mem_pestat] mean and std.dev: (451.64, 412.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2728)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699894 sequences (100000069 bp) in 2.218 CPU sec, 2.238 real sec...
[M::mem_process_seqs] Processed 702176 reads in 239.372 CPU sec, 7.762 real sec
sorting block 92, #reads = 1064522 mem = 536877866 peak = 897064960
[M::mem_process_seqs] Processed 702480 reads in 154.423 CPU sec, 4.934 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 285480, 11, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 361, 967)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2503)
[M::mem_pestat] mean and std.dev: (540.97, 497.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3271)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 232, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 720)
[M::mem_pestat] mean and std.dev: (261.21, 133.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 908)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (253, 710, 1564)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4186)
[M::mem_pestat] mean and std.dev: (1045.73, 1075.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5497)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 300, 969)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2529)
[M::mem_pestat] mean and std.dev: (524.04, 455.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3309)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 93, #reads = 1073131 mem = 536880831 peak = 897064960
[M::process] read 698998 sequences (100000170 bp) in 2.910 CPU sec, 3.218 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 284915, 32, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (251, 430, 934)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2300)
[M::mem_pestat] mean and std.dev: (558.48, 459.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2983)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 234, 347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 727)
[M::mem_pestat] mean and std.dev: (263.14, 134.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 917)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (272, 1079, 1333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3455)
[M::mem_pestat] mean and std.dev: (860.84, 570.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4516)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (308, 601, 803)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1793)
[M::mem_pestat] mean and std.dev: (599.50, 419.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2288)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698814 sequences (100000272 bp) in 2.038 CPU sec, 2.089 real sec...
[M::mem_process_seqs] Processed 700784 reads in 209.144 CPU sec, 6.706 real sec
[M::mem_process_seqs] Processed 699894 reads in 137.842 CPU sec, 4.629 real sec
sorting block 94, #reads = 1074678 mem = 536878584 peak = 897064960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 284639, 19, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 400, 1423)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3859)
[M::mem_pestat] mean and std.dev: (646.58, 610.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5077)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 238, 352)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 738)
[M::mem_pestat] mean and std.dev: (266.77, 136.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 931)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (444, 1171, 2489)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6579)
[M::mem_pestat] mean and std.dev: (1536.06, 1485.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8624)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (246, 358, 1064)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2700)
[M::mem_pestat] mean and std.dev: (650.42, 604.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3518)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698374 sequences (100000172 bp) in 3.344 CPU sec, 3.631 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 284877, 41, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 462, 1124)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3034)
[M::mem_pestat] mean and std.dev: (589.57, 504.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3989)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 238, 355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 745)
[M::mem_pestat] mean and std.dev: (268.59, 138.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 940)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 1252, 2217)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6321)
[M::mem_pestat] mean and std.dev: (1343.29, 1227.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8373)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 248, 483)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1061)
[M::mem_pestat] mean and std.dev: (263.53, 121.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1350)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698116 sequences (100000082 bp) in 2.068 CPU sec, 2.111 real sec...
[M::mem_process_seqs] Processed 698998 reads in 210.234 CPU sec, 6.995 real sec
[M::mem_process_seqs] Processed 698814 reads in 136.771 CPU sec, 4.445 real sec
sorting block 95, #reads = 1076027 mem = 536878051 peak = 897064960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 284434, 16, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 300, 575)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1317)
[M::mem_pestat] mean and std.dev: (360.00, 220.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1688)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 240, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 757)
[M::mem_pestat] mean and std.dev: (270.76, 140.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 956)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (902, 1483, 4552)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 11852)
[M::mem_pestat] mean and std.dev: (2168.88, 1816.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 15502)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 599, 1058)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2720)
[M::mem_pestat] mean and std.dev: (662.65, 578.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3551)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698216 sequences (100000042 bp) in 2.958 CPU sec, 3.479 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 284766, 26, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 271, 2895)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8345)
[M::mem_pestat] mean and std.dev: (1472.18, 1982.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11070)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 242, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 758)
[M::mem_pestat] mean and std.dev: (271.68, 140.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 957)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (774, 1747, 5862)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 16038)
[M::mem_pestat] mean and std.dev: (2558.81, 2269.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 21126)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 263, 524)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1296)
[M::mem_pestat] mean and std.dev: (346.65, 263.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1682)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698298 sequences (100000129 bp) in 2.030 CPU sec, 2.031 real sec...
[M::mem_process_seqs] Processed 698374 reads in 207.518 CPU sec, 6.763 real sec
sorting block 96, #reads = 1077209 mem = 536883854 peak = 897064960
[M::mem_process_seqs] Processed 698116 reads in 135.458 CPU sec, 4.354 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 285095, 12, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 221, 627)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1569)
[M::mem_pestat] mean and std.dev: (325.12, 267.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2040)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 241, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 752)
[M::mem_pestat] mean and std.dev: (270.67, 139.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 949)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 625, 2190)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6146)
[M::mem_pestat] mean and std.dev: (925.17, 935.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8124)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (262, 594, 1408)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3700)
[M::mem_pestat] mean and std.dev: (875.54, 716.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4846)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697228 sequences (100000113 bp) in 2.857 CPU sec, 3.275 real sec...
sorting block 97, #reads = 1076528 mem = 536877280 peak = 897064960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 284749, 22, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (237, 377, 1097)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2817)
[M::mem_pestat] mean and std.dev: (683.60, 651.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3677)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 240, 356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 746)
[M::mem_pestat] mean and std.dev: (269.60, 137.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 941)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (338, 881, 2040)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5444)
[M::mem_pestat] mean and std.dev: (1247.67, 1238.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7146)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 382, 883)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2233)
[M::mem_pestat] mean and std.dev: (644.47, 604.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3062)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696630 sequences (100000102 bp) in 2.241 CPU sec, 2.243 real sec...
[M::mem_process_seqs] Processed 698216 reads in 216.897 CPU sec, 7.013 real sec
[M::mem_process_seqs] Processed 698298 reads in 143.212 CPU sec, 4.623 real sec
sorting block 98, #reads = 1075120 mem = 536878912 peak = 897064960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23, 284181, 19, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (229, 294, 374)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 664)
[M::mem_pestat] mean and std.dev: (283.95, 104.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 809)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 244, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 762)
[M::mem_pestat] mean and std.dev: (273.04, 140.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 962)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (57, 355, 2086)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6144)
[M::mem_pestat] mean and std.dev: (1181.84, 1314.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8173)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (331, 499, 980)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2278)
[M::mem_pestat] mean and std.dev: (601.12, 412.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2927)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697060 sequences (100000146 bp) in 2.867 CPU sec, 3.332 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 284268, 14, 24)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 370, 887)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2283)
[M::mem_pestat] mean and std.dev: (456.56, 371.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2981)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 247, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 764)
[M::mem_pestat] mean and std.dev: (275.28, 140.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 964)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (81, 635, 1468)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4242)
[M::mem_pestat] mean and std.dev: (708.00, 845.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5629)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (232, 311, 943)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2365)
[M::mem_pestat] mean and std.dev: (512.36, 508.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3076)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696616 sequences (100000142 bp) in 2.174 CPU sec, 2.228 real sec...
[M::mem_process_seqs] Processed 697228 reads in 215.994 CPU sec, 7.049 real sec
[M::mem_process_seqs] Processed 696630 reads in 140.272 CPU sec, 4.558 real sec
sorting block 99, #reads = 1073583 mem = 536880399 peak = 897064960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 283796, 16, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (251, 397, 864)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2090)
[M::mem_pestat] mean and std.dev: (462.55, 380.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2703)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 245, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 766)
[M::mem_pestat] mean and std.dev: (274.61, 141.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 967)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (45, 437, 907)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2631)
[M::mem_pestat] mean and std.dev: (523.93, 627.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3493)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 565, 1005)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2647)
[M::mem_pestat] mean and std.dev: (722.60, 655.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3468)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696296 sequences (100000128 bp) in 2.974 CPU sec, 3.263 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 283386, 28, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 242, 812)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2108)
[M::mem_pestat] mean and std.dev: (433.86, 427.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2756)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 246, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 767)
[M::mem_pestat] mean and std.dev: (275.61, 141.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 968)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (437, 778, 1299)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3023)
[M::mem_pestat] mean and std.dev: (755.75, 532.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3885)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 452, 1138)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2960)
[M::mem_pestat] mean and std.dev: (752.32, 726.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3871)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696650 sequences (100000172 bp) in 2.171 CPU sec, 2.179 real sec...
[M::mem_process_seqs] Processed 697060 reads in 214.003 CPU sec, 6.935 real sec
[M::mem_process_seqs] Processed 696616 reads in 139.599 CPU sec, 4.515 real sec
sorting block 100, #reads = 1074220 mem = 536882571 peak = 897064960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 283597, 24, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (237, 316, 607)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1347)
[M::mem_pestat] mean and std.dev: (358.12, 235.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1717)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 247, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 773)
[M::mem_pestat] mean and std.dev: (277.25, 143.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 976)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (86, 437, 1127)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3209)
[M::mem_pestat] mean and std.dev: (433.64, 444.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4250)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (266, 353, 1025)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2543)
[M::mem_pestat] mean and std.dev: (591.04, 607.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3302)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695884 sequences (100000195 bp) in 2.690 CPU sec, 2.968 real sec...
sorting block 101, #reads = 1073436 mem = 536879373 peak = 897064960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 283171, 41, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 387, 1529)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4215)
[M::mem_pestat] mean and std.dev: (740.36, 852.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5558)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 245, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 769)
[M::mem_pestat] mean and std.dev: (275.53, 142.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 971)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (325, 419, 1223)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3019)
[M::mem_pestat] mean and std.dev: (629.59, 450.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3917)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 397, 601)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1371)
[M::mem_pestat] mean and std.dev: (472.89, 336.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1820)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696220 sequences (100000010 bp) in 2.235 CPU sec, 2.294 real sec...
[M::mem_process_seqs] Processed 696296 reads in 214.078 CPU sec, 6.943 real sec
[M::mem_process_seqs] Processed 696650 reads in 143.211 CPU sec, 4.649 real sec
sorting block 102, #reads = 1072339 mem = 536878734 peak = 897064960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 283018, 23, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (243, 422, 531)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1107)
[M::mem_pestat] mean and std.dev: (357.24, 172.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1395)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 247, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 768)
[M::mem_pestat] mean and std.dev: (276.78, 142.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 969)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (285, 493, 1279)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3267)
[M::mem_pestat] mean and std.dev: (755.17, 598.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4261)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 385, 1011)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2627)
[M::mem_pestat] mean and std.dev: (644.14, 567.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3435)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696180 sequences (100000166 bp) in 3.024 CPU sec, 3.376 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 283392, 30, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 401, 785)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1951)
[M::mem_pestat] mean and std.dev: (477.49, 392.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2534)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 246, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 770)
[M::mem_pestat] mean and std.dev: (276.52, 142.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 972)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (143, 451, 939)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2531)
[M::mem_pestat] mean and std.dev: (558.86, 476.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3327)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (284, 457, 989)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2399)
[M::mem_pestat] mean and std.dev: (619.14, 441.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3104)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696370 sequences (100000169 bp) in 2.084 CPU sec, 2.115 real sec...
[M::mem_process_seqs] Processed 695884 reads in 218.054 CPU sec, 7.074 real sec
[M::mem_process_seqs] Processed 696220 reads in 145.271 CPU sec, 4.644 real sec
sorting block 103, #reads = 1072196 mem = 536877157 peak = 897064960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 283102, 16, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (313, 653, 2435)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6679)
[M::mem_pestat] mean and std.dev: (917.75, 889.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8801)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 245, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 767)
[M::mem_pestat] mean and std.dev: (275.88, 142.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 968)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (341, 1193, 4250)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12068)
[M::mem_pestat] mean and std.dev: (2420.12, 2761.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 15977)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (273, 796, 1606)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4272)
[M::mem_pestat] mean and std.dev: (950.40, 863.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5605)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696176 sequences (100000009 bp) in 3.431 CPU sec, 3.849 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 283228, 16, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (132, 152, 689)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1803)
[M::mem_pestat] mean and std.dev: (372.09, 394.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2360)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 244, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 763)
[M::mem_pestat] mean and std.dev: (274.50, 141.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 963)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (247, 1352, 2123)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5875)
[M::mem_pestat] mean and std.dev: (1227.38, 988.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7751)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (246, 388, 753)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1767)
[M::mem_pestat] mean and std.dev: (496.24, 385.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2274)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696180 reads in 215.129 CPU sec, 6.903 real sec
[M::process] read 696096 sequences (100000223 bp) in 2.354 CPU sec, 2.477 real sec...
[M::mem_process_seqs] Processed 696370 reads in 155.399 CPU sec, 4.964 real sec
sorting block 104, #reads = 1070949 mem = 536883831 peak = 897064960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 283267, 16, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 289, 491)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1143)
[M::mem_pestat] mean and std.dev: (334.64, 254.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1469)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 245, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 767)
[M::mem_pestat] mean and std.dev: (275.83, 142.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 968)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (90, 760, 2551)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7473)
[M::mem_pestat] mean and std.dev: (1492.19, 2006.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9934)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (265, 435, 1491)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3943)
[M::mem_pestat] mean and std.dev: (608.21, 518.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5169)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703840 sequences (100000185 bp) in 3.051 CPU sec, 3.348 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 282835, 13, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (228, 341, 507)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1065)
[M::mem_pestat] mean and std.dev: (342.46, 218.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1344)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 246, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 770)
[M::mem_pestat] mean and std.dev: (276.60, 143.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 972)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (353, 1198, 1616)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4142)
[M::mem_pestat] mean and std.dev: (1019.00, 777.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5405)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 305, 619)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1453)
[M::mem_pestat] mean and std.dev: (342.44, 213.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1870)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 707058 sequences (100000075 bp) in 2.301 CPU sec, 2.357 real sec...
[M::mem_process_seqs] Processed 696176 reads in 225.995 CPU sec, 7.227 real sec
sorting block 105, #reads = 1070796 mem = 536881725 peak = 897064960
[M::mem_process_seqs] Processed 696096 reads in 157.624 CPU sec, 5.264 real sec
sorting block 106, #reads = 1068203 mem = 536878199 peak = 897064960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 284947, 16, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 354, 891)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2309)
[M::mem_pestat] mean and std.dev: (450.57, 401.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3018)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 223, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 689)
[M::mem_pestat] mean and std.dev: (251.76, 129.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 868)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1150, 1212, 8670)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 23710)
[M::mem_pestat] mean and std.dev: (3796.62, 3486.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 31230)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (273, 736, 1016)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2502)
[M::mem_pestat] mean and std.dev: (734.86, 559.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3245)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704410 sequences (100000297 bp) in 3.105 CPU sec, 3.437 real sec...
[M::process] read 702644 sequences (100000244 bp) in 2.089 CPU sec, 2.097 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23, 287249, 24, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (126, 363, 896)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2436)
[M::mem_pestat] mean and std.dev: (496.36, 454.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3206)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 215, 316)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 652)
[M::mem_pestat] mean and std.dev: (242.24, 122.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 820)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 486, 4351)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12659)
[M::mem_pestat] mean and std.dev: (1515.83, 1810.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 16813)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 260, 607)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1513)
[M::mem_pestat] mean and std.dev: (368.21, 361.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1966)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703840 reads in 255.707 CPU sec, 8.462 real sec
[M::mem_process_seqs] Processed 707058 reads in 165.762 CPU sec, 5.301 real sec
sorting block 107, #reads = 1062581 mem = 536882271 peak = 897064960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 286212, 11, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (290, 503, 1092)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2696)
[M::mem_pestat] mean and std.dev: (698.48, 597.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3498)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 221, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 682)
[M::mem_pestat] mean and std.dev: (250.28, 127.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 859)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (116, 185, 465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1163)
[M::mem_pestat] mean and std.dev: (239.50, 178.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1512)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 294, 397)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 887)
[M::mem_pestat] mean and std.dev: (295.69, 179.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1132)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702186 sequences (100000112 bp) in 2.856 CPU sec, 3.084 real sec...
[M::process] read 701960 sequences (100000141 bp) in 2.160 CPU sec, 2.169 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 285706, 19, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 248, 561)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1357)
[M::mem_pestat] mean and std.dev: (335.26, 242.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1755)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 227, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 697)
[M::mem_pestat] mean and std.dev: (254.54, 128.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 878)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (283, 471, 2313)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6373)
[M::mem_pestat] mean and std.dev: (1036.42, 1032.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8403)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 322, 446)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 886)
[M::mem_pestat] mean and std.dev: (308.46, 150.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1106)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704410 reads in 237.197 CPU sec, 7.701 real sec
[M::mem_process_seqs] Processed 702644 reads in 153.375 CPU sec, 4.987 real sec
sorting block 108, #reads = 1072034 mem = 536880941 peak = 897064960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 285287, 24, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (121, 240, 535)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1363)
[M::mem_pestat] mean and std.dev: (257.50, 188.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1777)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 229, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 712)
[M::mem_pestat] mean and std.dev: (257.47, 131.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 898)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (122, 330, 1179)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3293)
[M::mem_pestat] mean and std.dev: (464.50, 544.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4350)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 358, 1304)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3566)
[M::mem_pestat] mean and std.dev: (590.97, 681.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4697)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700730 sequences (100000055 bp) in 3.827 CPU sec, 4.240 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 285576, 21, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (264, 378, 967)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2373)
[M::mem_pestat] mean and std.dev: (465.21, 354.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3076)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 228, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 710)
[M::mem_pestat] mean and std.dev: (258.44, 132.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 895)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (333, 452, 1123)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2703)
[M::mem_pestat] mean and std.dev: (677.60, 615.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3493)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (234, 428, 728)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1716)
[M::mem_pestat] mean and std.dev: (436.07, 239.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2210)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699464 sequences (100000115 bp) in 2.137 CPU sec, 2.139 real sec...
[M::mem_process_seqs] Processed 702186 reads in 239.590 CPU sec, 7.710 real sec
sorting block 109, #reads = 1069592 mem = 536880349 peak = 897064960
[M::mem_process_seqs] Processed 701960 reads in 162.962 CPU sec, 5.188 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 284517, 22, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (241, 395, 706)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1636)
[M::mem_pestat] mean and std.dev: (484.80, 316.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2101)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 232, 346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 726)
[M::mem_pestat] mean and std.dev: (262.43, 134.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 916)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (325, 877, 1060)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2530)
[M::mem_pestat] mean and std.dev: (783.48, 509.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3265)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 302, 650)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1600)
[M::mem_pestat] mean and std.dev: (369.08, 289.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2075)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 110, #reads = 1069338 mem = 536878724 peak = 897064960
[M::process] read 699772 sequences (100000257 bp) in 4.754 CPU sec, 5.156 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 284713, 16, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 549, 1403)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3791)
[M::mem_pestat] mean and std.dev: (835.64, 834.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4985)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 235, 351)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 737)
[M::mem_pestat] mean and std.dev: (265.93, 136.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 930)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (100, 233, 242)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 526)
[M::mem_pestat] mean and std.dev: (172.29, 124.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 669)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 484, 715)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1751)
[M::mem_pestat] mean and std.dev: (524.09, 405.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2269)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700730 reads in 224.627 CPU sec, 7.182 real sec
[M::mem_process_seqs] Processed 699464 reads in 152.051 CPU sec, 4.815 real sec
[M::process] read 698690 sequences (100000153 bp) in 2.454 CPU sec, 2.556 real sec...
sorting block 111, #reads = 1072085 mem = 536881389 peak = 897064960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 284789, 12, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (260, 422, 872)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2096)
[M::mem_pestat] mean and std.dev: (439.64, 313.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2708)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 234, 348)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 728)
[M::mem_pestat] mean and std.dev: (263.68, 134.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 918)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (389, 873, 1984)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5174)
[M::mem_pestat] mean and std.dev: (830.80, 652.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6769)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 612, 1050)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2722)
[M::mem_pestat] mean and std.dev: (741.37, 657.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3558)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696588 sequences (100000145 bp) in 3.468 CPU sec, 3.746 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 283866, 15, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 344, 959)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2491)
[M::mem_pestat] mean and std.dev: (534.60, 475.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3257)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 237, 351)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 733)
[M::mem_pestat] mean and std.dev: (266.21, 135.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 924)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (395, 800, 1604)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4022)
[M::mem_pestat] mean and std.dev: (852.57, 709.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5231)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 245, 876)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2226)
[M::mem_pestat] mean and std.dev: (539.91, 500.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2901)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698290 sequences (100000023 bp) in 2.065 CPU sec, 2.071 real sec...
[M::mem_process_seqs] Processed 699772 reads in 225.951 CPU sec, 7.206 real sec
[M::mem_process_seqs] Processed 698690 reads in 144.890 CPU sec, 4.681 real sec
sorting block 112, #reads = 1071237 mem = 536880875 peak = 897064960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 283526, 34, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 358, 586)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1398)
[M::mem_pestat] mean and std.dev: (335.36, 196.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1804)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 246, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 764)
[M::mem_pestat] mean and std.dev: (274.88, 140.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 964)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (424, 627, 1157)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2623)
[M::mem_pestat] mean and std.dev: (723.69, 505.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3356)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 326, 1317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3533)
[M::mem_pestat] mean and std.dev: (663.26, 707.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4641)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697638 sequences (100000137 bp) in 3.036 CPU sec, 3.255 real sec...
[M::process] read 696698 sequences (100000076 bp) in 2.060 CPU sec, 2.060 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 283996, 21, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 259, 521)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1195)
[M::mem_pestat] mean and std.dev: (303.20, 203.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1532)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 238, 352)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 736)
[M::mem_pestat] mean and std.dev: (267.36, 136.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 928)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (305, 642, 2618)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7244)
[M::mem_pestat] mean and std.dev: (937.56, 1104.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9557)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (232, 516, 2772)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7852)
[M::mem_pestat] mean and std.dev: (1647.10, 2152.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10392)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696588 reads in 211.796 CPU sec, 6.831 real sec
sorting block 113, #reads = 1069160 mem = 536877770 peak = 897064960
[M::mem_process_seqs] Processed 698290 reads in 140.427 CPU sec, 4.545 real sec
sorting block 114, #reads = 1069689 mem = 536880971 peak = 897064960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 283376, 31, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 344, 4289)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12525)
[M::mem_pestat] mean and std.dev: (1557.81, 2136.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 16643)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 241, 357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 747)
[M::mem_pestat] mean and std.dev: (270.33, 137.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 942)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (326, 555, 2656)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7316)
[M::mem_pestat] mean and std.dev: (1266.07, 1326.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9646)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 338, 1323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3593)
[M::mem_pestat] mean and std.dev: (898.70, 1034.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5037)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696674 sequences (100000062 bp) in 2.830 CPU sec, 2.995 real sec...
[M::process] read 696638 sequences (100000227 bp) in 2.091 CPU sec, 2.098 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 283724, 22, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 363, 776)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1886)
[M::mem_pestat] mean and std.dev: (427.65, 285.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2441)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 243, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 748)
[M::mem_pestat] mean and std.dev: (271.24, 137.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 943)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (335, 1365, 2058)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5504)
[M::mem_pestat] mean and std.dev: (980.37, 766.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7227)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 283, 601)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1405)
[M::mem_pestat] mean and std.dev: (356.76, 237.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1807)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697638 reads in 215.089 CPU sec, 6.935 real sec
[M::mem_process_seqs] Processed 696698 reads in 140.845 CPU sec, 4.538 real sec
sorting block 115, #reads = 1069448 mem = 536881929 peak = 897064960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 283676, 21, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 429, 990)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2616)
[M::mem_pestat] mean and std.dev: (594.48, 647.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3429)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 243, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 748)
[M::mem_pestat] mean and std.dev: (271.73, 138.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 943)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (341, 666, 1159)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2795)
[M::mem_pestat] mean and std.dev: (714.40, 589.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3613)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 421, 1570)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4364)
[M::mem_pestat] mean and std.dev: (711.05, 670.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5761)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696828 sequences (100000135 bp) in 2.808 CPU sec, 2.961 real sec...
[M::process] read 697132 sequences (100000003 bp) in 1.933 CPU sec, 1.935 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 283442, 38, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 439, 1452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3974)
[M::mem_pestat] mean and std.dev: (916.53, 1014.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5235)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 243, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 751)
[M::mem_pestat] mean and std.dev: (272.18, 138.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 947)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 496, 2198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6244)
[M::mem_pestat] mean and std.dev: (1322.55, 1520.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8267)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 355, 943)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2413)
[M::mem_pestat] mean and std.dev: (458.21, 366.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3148)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696674 reads in 213.808 CPU sec, 6.877 real sec
[M::mem_process_seqs] Processed 696638 reads in 139.987 CPU sec, 4.533 real sec
sorting block 116, #reads = 1072414 mem = 536879615 peak = 897064960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 283691, 21, 22)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 321, 607)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1441)
[M::mem_pestat] mean and std.dev: (354.38, 249.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1858)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 242, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 756)
[M::mem_pestat] mean and std.dev: (272.71, 140.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 954)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (298, 581, 1679)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4441)
[M::mem_pestat] mean and std.dev: (794.15, 709.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5822)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 263, 656)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1634)
[M::mem_pestat] mean and std.dev: (371.75, 317.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2123)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696750 sequences (100000037 bp) in 2.862 CPU sec, 3.044 real sec...
[M::process] read 695178 sequences (100000163 bp) in 1.858 CPU sec, 1.863 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 283802, 24, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (232, 329, 661)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1519)
[M::mem_pestat] mean and std.dev: (440.85, 333.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1948)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 241, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 756)
[M::mem_pestat] mean and std.dev: (272.21, 140.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 954)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (364, 590, 747)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1513)
[M::mem_pestat] mean and std.dev: (509.36, 325.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1896)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 751, 1935)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5317)
[M::mem_pestat] mean and std.dev: (1370.67, 1633.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7905)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696828 reads in 214.557 CPU sec, 6.928 real sec
sorting block 117, #reads = 1072336 mem = 536880005 peak = 897064960
[M::mem_process_seqs] Processed 697132 reads in 140.637 CPU sec, 4.572 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 283352, 21, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (276, 390, 1043)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2577)
[M::mem_pestat] mean and std.dev: (670.29, 634.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3344)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 243, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 757)
[M::mem_pestat] mean and std.dev: (273.42, 140.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 955)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 587, 2107)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5891)
[M::mem_pestat] mean and std.dev: (1122.33, 1160.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7783)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (276, 1114, 1997)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5439)
[M::mem_pestat] mean and std.dev: (1215.64, 1120.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7160)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 118, #reads = 1072357 mem = 536877477 peak = 897064960
[M::process] read 696066 sequences (100000058 bp) in 3.078 CPU sec, 3.243 real sec...
[M::process] read 213982 sequences (30693419 bp) in 0.872 CPU sec, 0.875 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 282700, 34, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (268, 446, 702)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1570)
[M::mem_pestat] mean and std.dev: (401.06, 210.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2004)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 250, 372)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 784)
[M::mem_pestat] mean and std.dev: (280.86, 145.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 990)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (55, 287, 773)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2209)
[M::mem_pestat] mean and std.dev: (348.77, 373.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2927)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 506, 1039)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2759)
[M::mem_pestat] mean and std.dev: (592.52, 526.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3619)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696750 reads in 217.726 CPU sec, 7.066 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 283505, 31, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 316, 997)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2627)
[M::mem_pestat] mean and std.dev: (636.37, 686.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3442)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 246, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 764)
[M::mem_pestat] mean and std.dev: (275.95, 141.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 964)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (311, 434, 1443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3707)
[M::mem_pestat] mean and std.dev: (972.35, 977.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4883)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 318, 871)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2239)
[M::mem_pestat] mean and std.dev: (479.83, 450.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2923)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696066 reads in 120.805 CPU sec, 4.008 real sec
sorting block 119, #reads = 1071002 mem = 536883263 peak = 897064960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 87018, 12, 14)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (245, 442, 1547)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4151)
[M::mem_pestat] mean and std.dev: (720.96, 706.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5453)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 242, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 750)
[M::mem_pestat] mean and std.dev: (271.14, 138.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 946)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (328, 476, 544)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 976)
[M::mem_pestat] mean and std.dev: (354.55, 209.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1192)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (277, 358, 1720)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4606)
[M::mem_pestat] mean and std.dev: (646.42, 747.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6049)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 213982 reads in 65.183 CPU sec, 2.144 real sec
[M::mem_process_seqs] Processed 695178 reads in 298.785 CPU sec, 10.109 real sec
sorting block 120, #reads = 1069009 mem = 536877842 peak = 897064960
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000a06d1
  features: 1f8bfbff fffab20b
  extended: f1bf27eb 1b407f7e
  amd bits: 2c100800 00000121
     brand: Intel(R) Xeon(R) 6975P-C
threads: 31
algo: bwa-mem
license: sentieon:klib=31
reads: 129213598
overall: 69428469760 mem 23006.885 user 960.907 sys 794.194 real
[main] Version: 0.7.17-r1188
[main] CMD: /opt/conda/share/sentieon-202308.03-3/libexec/bwa mem -K 100000000 -Y -R @RG\tID:A23MHWWLT4.1136_4GR-T1-TDNA-1_A23MHWWLT4_1.L007\tPU:L007\tSM:1136_4GR-T1-TDNA-1_A23MHWWLT4_1\tLB:1136_4GR-T1-TDNA-1_A23MHWWLT4_1\tDS:s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta\tPL:ILLUMINA -t 31 ./BWAIndex/Homo_sapiens_assembly38.fasta.64 1136_4GR-T1-TDNA-1_A23MHWWLT4_1_R1.fastq.gz 1136_4GR-T1-TDNA-1_A23MHWWLT4_1_R2.fastq.gz
[main] Real time: 794.237 sec; CPU: 23967.799 sec
sorting block 121, #reads = 330368 mem = 165850344 peak = 897064960
uniq header count 1
merging 122 blocks
sw version: sentieon-genomics-202308.03
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000a06d1
  features: 1f8bfbff fffab20b
  extended: f1bf27eb 1b407f7e
  amd bits: 2c100800 00000121
     brand: Intel(R) Xeon(R) 6975P-C
threads: 31 max 384
algo: util-sort
license: sentieon:util=1
output file size: 7460105052
output reads: 130295262
bam_mem_sort: 122 calls 106.629 user 2.666 sys 110.788 real
bam_write: 122 calls 74.697 user 6.596 sys 117.460 real
execute: 1 calls 46.685 user 3.016 sys 847.132 real
merge_files: 1 calls 46.654 user 2.995 sys 52.607 real
parse_chunk: 1941 calls 92.232 user 26.788 sys 135.965 real
read_chunk: 5250 calls 66.701 user 29.308 sys 713.871 real
sort_block: 1 calls 47.726 user 27.962 sys 687.429 real
write_chunk: 3307 calls 46.169 user 2.637 sys 51.443 real
overall: 3085201408 mem 2023.497 user 114.740 sys 847.153 real
ls: cannot access '*.cram': No such file or directory