This software is licensed to bgold@natera.com by Sentieon Inc.
cmdline: /opt/conda/share/sentieon-202308.03-3/libexec/util sort -r Homo_sapiens_assembly38.fasta -t 31 -o 1136_8DV-T1-TDNA-1_A23MHWWLT4_1.bam --sam2bam -
This software is licensed to bgold@natera.com by Sentieon Inc.
version: sentieon-genomics-202308.03
[M::bwa_idx_load_from_disk] read 3171 ALT contigs
[M::main_mem] bwa index loaded in 2909.637 CPU sec, 118.847 real sec
[M::process] read 719092 sequences (100000138 bp) in 1.191 CPU sec, 1.196 real sec...
[M::process] read 715692 sequences (100000092 bp) in 1.819 CPU sec, 1.822 real sec...
[M::process] read 718702 sequences (100000257 bp) in 1.839 CPU sec, 1.836 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 289803, 25, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (125, 277, 427)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1031)
[M::mem_pestat] mean and std.dev: (222.17, 124.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1333)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 199, 307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 647)
[M::mem_pestat] mean and std.dev: (231.70, 124.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 817)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (332, 568, 1627)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4217)
[M::mem_pestat] mean and std.dev: (834.64, 777.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5512)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 261, 461)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1003)
[M::mem_pestat] mean and std.dev: (297.69, 200.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1274)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 719792 sequences (100000184 bp) in 1.772 CPU sec, 1.777 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 288905, 13, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 340, 506)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1170)
[M::mem_pestat] mean and std.dev: (304.86, 194.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1502)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (140, 206, 319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 677)
[M::mem_pestat] mean and std.dev: (239.69, 129.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 856)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (425, 674, 1104)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2462)
[M::mem_pestat] mean and std.dev: (580.92, 379.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3141)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 282, 666)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1600)
[M::mem_pestat] mean and std.dev: (313.55, 213.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2067)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 289876, 31, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 273, 644)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1496)
[M::mem_pestat] mean and std.dev: (304.83, 188.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1922)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 200, 308)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 650)
[M::mem_pestat] mean and std.dev: (232.19, 124.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 821)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (414, 793, 1036)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2280)
[M::mem_pestat] mean and std.dev: (736.68, 517.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2902)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 369, 1104)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2824)
[M::mem_pestat] mean and std.dev: (452.53, 481.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3684)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 719092 reads in 338.474 CPU sec, 10.827 real sec
[M::mem_process_seqs] Processed 715692 reads in 229.979 CPU sec, 7.442 real sec
[M::mem_process_seqs] Processed 718702 reads in 253.141 CPU sec, 8.204 real sec
sorting block 0, #reads = 1088394 mem = 536886346 peak = 574705664
[M::process] read 720920 sequences (100000090 bp) in 2.463 CPU sec, 2.638 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 290542, 16, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 284, 950)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2526)
[M::mem_pestat] mean and std.dev: (491.15, 496.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3314)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 198, 305)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 643)
[M::mem_pestat] mean and std.dev: (229.93, 123.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 812)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (58, 1331, 1665)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4879)
[M::mem_pestat] mean and std.dev: (858.80, 725.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6486)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 338, 1081)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2813)
[M::mem_pestat] mean and std.dev: (523.77, 507.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3679)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 715764 sequences (100000168 bp) in 2.314 CPU sec, 2.444 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20, 291035, 23, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 252, 684)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1692)
[M::mem_pestat] mean and std.dev: (358.35, 267.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2196)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 196, 300)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 630)
[M::mem_pestat] mean and std.dev: (226.77, 120.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 795)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (339, 1206, 2237)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6033)
[M::mem_pestat] mean and std.dev: (1626.35, 1800.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8830)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 255, 892)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2280)
[M::mem_pestat] mean and std.dev: (436.97, 380.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2974)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720104 sequences (100000009 bp) in 2.010 CPU sec, 2.006 real sec...
[M::mem_process_seqs] Processed 719792 reads in 215.617 CPU sec, 6.849 real sec
sorting block 1, #reads = 1089749 mem = 536877620 peak = 811495424
[M::mem_process_seqs] Processed 720920 reads in 141.741 CPU sec, 4.492 real sec
sorting block 2, #reads = 1092182 mem = 536878073 peak = 839811072
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 288876, 16, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 240, 1611)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4427)
[M::mem_pestat] mean and std.dev: (822.80, 1039.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5835)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (140, 207, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 686)
[M::mem_pestat] mean and std.dev: (241.62, 131.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 868)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (286, 751, 1249)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3175)
[M::mem_pestat] mean and std.dev: (739.87, 517.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4138)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 611, 649)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1495)
[M::mem_pestat] mean and std.dev: (455.00, 289.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1918)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 719600 sequences (100000288 bp) in 2.876 CPU sec, 3.111 real sec...
[M::process] read 719366 sequences (100000083 bp) in 1.949 CPU sec, 1.980 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 290675, 20, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 338, 1672)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4634)
[M::mem_pestat] mean and std.dev: (1051.86, 1294.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6230)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 197, 304)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 640)
[M::mem_pestat] mean and std.dev: (229.38, 122.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 808)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (256, 477, 1126)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2866)
[M::mem_pestat] mean and std.dev: (662.78, 683.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3736)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 581, 1289)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3463)
[M::mem_pestat] mean and std.dev: (739.89, 537.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4550)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 715764 reads in 217.686 CPU sec, 7.152 real sec
[M::mem_process_seqs] Processed 720104 reads in 142.056 CPU sec, 4.572 real sec
sorting block 3, #reads = 1090588 mem = 536878135 peak = 839811072
[M::process] read 717356 sequences (100000144 bp) in 2.806 CPU sec, 3.035 real sec...
[M::process] read 716626 sequences (100000015 bp) in 1.673 CPU sec, 1.675 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 290184, 12, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (137, 309, 800)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2126)
[M::mem_pestat] mean and std.dev: (577.74, 614.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3037)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 198, 303)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 635)
[M::mem_pestat] mean and std.dev: (229.28, 121.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 801)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (307, 734, 1711)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4519)
[M::mem_pestat] mean and std.dev: (868.08, 707.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5923)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 251, 374)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 706)
[M::mem_pestat] mean and std.dev: (276.23, 129.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 872)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 719366 reads in 117.537 CPU sec, 3.774 real sec
sorting block 4, #reads = 1091656 mem = 536877833 peak = 839811072
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (21, 290481, 17, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 324, 525)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1253)
[M::mem_pestat] mean and std.dev: (363.86, 259.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1617)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 198, 304)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 638)
[M::mem_pestat] mean and std.dev: (230.04, 122.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 805)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (108, 353, 1567)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4485)
[M::mem_pestat] mean and std.dev: (975.65, 1245.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5959)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (273, 297, 784)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1806)
[M::mem_pestat] mean and std.dev: (385.59, 251.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2317)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 289456, 18, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (125, 196, 566)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1448)
[M::mem_pestat] mean and std.dev: (254.77, 182.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1889)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 202, 309)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 651)
[M::mem_pestat] mean and std.dev: (233.56, 124.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 822)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (27, 319, 650)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1896)
[M::mem_pestat] mean and std.dev: (323.76, 354.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2519)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 282, 1085)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2875)
[M::mem_pestat] mean and std.dev: (537.24, 509.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3770)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 717952 sequences (100000105 bp) in 1.815 CPU sec, 1.818 real sec...
[M::mem_process_seqs] Processed 719600 reads in 333.625 CPU sec, 10.734 real sec
[M::mem_process_seqs] Processed 717356 reads in 173.581 CPU sec, 5.642 real sec
sorting block 5, #reads = 1092037 mem = 536878267 peak = 839811072
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 289357, 20, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 335, 1132)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3064)
[M::mem_pestat] mean and std.dev: (652.75, 638.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4030)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (139, 202, 309)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 649)
[M::mem_pestat] mean and std.dev: (233.56, 123.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 819)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (81, 291, 1140)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3258)
[M::mem_pestat] mean and std.dev: (675.42, 904.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4317)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (300, 662, 909)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2127)
[M::mem_pestat] mean and std.dev: (601.12, 359.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2736)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 716108 sequences (100000028 bp) in 3.056 CPU sec, 3.315 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 289578, 19, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 232, 733)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1887)
[M::mem_pestat] mean and std.dev: (434.74, 452.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2464)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 199, 303)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 633)
[M::mem_pestat] mean and std.dev: (229.25, 120.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 798)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (430, 546, 1329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3127)
[M::mem_pestat] mean and std.dev: (825.17, 637.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4026)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 387, 1271)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3419)
[M::mem_pestat] mean and std.dev: (568.97, 617.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4493)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 716626 reads in 220.162 CPU sec, 7.042 real sec
[M::process] read 717190 sequences (100000111 bp) in 2.319 CPU sec, 2.322 real sec...
[M::mem_process_seqs] Processed 717952 reads in 143.959 CPU sec, 4.801 real sec
sorting block 6, #reads = 1089252 mem = 536879213 peak = 839811072
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (19, 288989, 11, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (140, 238, 707)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1841)
[M::mem_pestat] mean and std.dev: (372.22, 372.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2408)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (139, 203, 310)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 652)
[M::mem_pestat] mean and std.dev: (234.31, 124.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 823)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 325, 574)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1408)
[M::mem_pestat] mean and std.dev: (391.09, 347.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1825)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 218, 913)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2401)
[M::mem_pestat] mean and std.dev: (473.97, 485.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3145)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 715666 sequences (100000072 bp) in 4.351 CPU sec, 4.799 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 289416, 15, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 241, 550)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1340)
[M::mem_pestat] mean and std.dev: (305.96, 255.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1735)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 200, 305)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 639)
[M::mem_pestat] mean and std.dev: (231.22, 121.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 806)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (307, 412, 1341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3409)
[M::mem_pestat] mean and std.dev: (748.87, 744.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4443)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (236, 407, 1860)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5108)
[M::mem_pestat] mean and std.dev: (1008.65, 1076.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6732)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 716108 reads in 221.157 CPU sec, 7.286 real sec
sorting block 7, #reads = 1090664 mem = 536877290 peak = 839811072
[M::mem_process_seqs] Processed 717190 reads in 146.092 CPU sec, 4.626 real sec
[M::process] read 715940 sequences (100000237 bp) in 3.312 CPU sec, 3.454 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 288935, 20, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 848, 1651)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4555)
[M::mem_pestat] mean and std.dev: (1194.83, 1237.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6145)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (140, 203, 310)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 650)
[M::mem_pestat] mean and std.dev: (234.56, 124.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 820)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (519, 1168, 2718)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7116)
[M::mem_pestat] mean and std.dev: (1673.85, 1943.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9449)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 203, 629)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1567)
[M::mem_pestat] mean and std.dev: (362.75, 322.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2036)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 8, #reads = 1088910 mem = 536878230 peak = 839811072
[M::process] read 717576 sequences (100000103 bp) in 3.331 CPU sec, 3.555 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 289198, 18, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (303, 949, 2176)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5922)
[M::mem_pestat] mean and std.dev: (1158.95, 1286.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7795)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (139, 204, 310)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 652)
[M::mem_pestat] mean and std.dev: (234.45, 123.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 823)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (458, 899, 1286)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2942)
[M::mem_pestat] mean and std.dev: (858.67, 537.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3770)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 225, 909)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2399)
[M::mem_pestat] mean and std.dev: (441.08, 419.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3144)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 715666 reads in 216.630 CPU sec, 6.924 real sec
[M::mem_process_seqs] Processed 715940 reads in 142.272 CPU sec, 4.496 real sec
[M::process] read 715508 sequences (100000274 bp) in 2.647 CPU sec, 2.741 real sec...
sorting block 9, #reads = 1088785 mem = 536878625 peak = 839811072
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 289389, 22, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 263, 666)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1616)
[M::mem_pestat] mean and std.dev: (365.72, 305.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2091)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 199, 303)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 633)
[M::mem_pestat] mean and std.dev: (229.46, 120.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 798)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (574, 1000, 1483)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3301)
[M::mem_pestat] mean and std.dev: (965.30, 438.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4210)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 295, 960)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2474)
[M::mem_pestat] mean and std.dev: (485.21, 357.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3231)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 717438 sequences (100000190 bp) in 3.352 CPU sec, 3.623 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 288695, 20, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 260, 1395)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3771)
[M::mem_pestat] mean and std.dev: (606.18, 571.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4959)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (140, 204, 310)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 650)
[M::mem_pestat] mean and std.dev: (234.47, 123.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 820)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (394, 423, 933)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2011)
[M::mem_pestat] mean and std.dev: (503.76, 304.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2550)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 252, 695)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1715)
[M::mem_pestat] mean and std.dev: (408.85, 320.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2225)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 716920 sequences (100000196 bp) in 1.713 CPU sec, 1.714 real sec...
[M::mem_process_seqs] Processed 717576 reads in 226.878 CPU sec, 7.262 real sec
[M::mem_process_seqs] Processed 715508 reads in 146.313 CPU sec, 4.656 real sec
sorting block 10, #reads = 1088330 mem = 536881209 peak = 839811072
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 289337, 16, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 404, 889)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2301)
[M::mem_pestat] mean and std.dev: (598.21, 523.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3007)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 200, 305)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 639)
[M::mem_pestat] mean and std.dev: (231.18, 122.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 806)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 623, 1057)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2825)
[M::mem_pestat] mean and std.dev: (490.93, 414.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3709)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (242, 353, 1172)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3032)
[M::mem_pestat] mean and std.dev: (577.16, 642.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3962)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 717170 sequences (100000137 bp) in 3.438 CPU sec, 3.685 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 289212, 12, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 338, 803)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2079)
[M::mem_pestat] mean and std.dev: (427.69, 381.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2717)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (139, 201, 308)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 646)
[M::mem_pestat] mean and std.dev: (232.62, 123.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 815)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (386, 588, 3188)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8792)
[M::mem_pestat] mean and std.dev: (1415.17, 1352.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11594)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 359, 1250)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3348)
[M::mem_pestat] mean and std.dev: (760.33, 789.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4397)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 718930 sequences (100000067 bp) in 2.150 CPU sec, 2.145 real sec...
[M::mem_process_seqs] Processed 717438 reads in 227.848 CPU sec, 7.339 real sec
sorting block 11, #reads = 1088497 mem = 536883989 peak = 839811072
[M::mem_process_seqs] Processed 716920 reads in 146.342 CPU sec, 4.752 real sec
sorting block 12, #reads = 1089091 mem = 536878537 peak = 839811072
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 289741, 17, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (238, 687, 2733)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7723)
[M::mem_pestat] mean and std.dev: (1615.72, 2069.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10218)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (139, 203, 312)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 658)
[M::mem_pestat] mean and std.dev: (235.04, 125.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 831)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (346, 1011, 2453)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6667)
[M::mem_pestat] mean and std.dev: (893.47, 779.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8774)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 278, 620)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1512)
[M::mem_pestat] mean and std.dev: (402.77, 346.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1958)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 717212 sequences (100000214 bp) in 3.470 CPU sec, 3.729 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23, 290073, 13, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 272, 484)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1130)
[M::mem_pestat] mean and std.dev: (322.15, 238.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1453)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 199, 306)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 644)
[M::mem_pestat] mean and std.dev: (230.53, 122.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 813)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (230, 553, 4715)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13685)
[M::mem_pestat] mean and std.dev: (1777.77, 2431.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 18170)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 295, 1071)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2779)
[M::mem_pestat] mean and std.dev: (623.39, 764.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3681)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 718194 sequences (100000038 bp) in 2.293 CPU sec, 2.299 real sec...
[M::mem_process_seqs] Processed 717170 reads in 220.989 CPU sec, 7.142 real sec
[M::mem_process_seqs] Processed 718930 reads in 140.859 CPU sec, 4.469 real sec
sorting block 13, #reads = 1088485 mem = 536878292 peak = 839811072
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 289792, 8, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 408, 1829)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5103)
[M::mem_pestat] mean and std.dev: (810.87, 901.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6740)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 203, 313)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 663)
[M::mem_pestat] mean and std.dev: (235.53, 126.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 838)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (141, 223, 351)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 771)
[M::mem_pestat] mean and std.dev: (253.50, 138.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 981)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 718440 sequences (100000207 bp) in 3.443 CPU sec, 3.654 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23, 290153, 17, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 207, 2020)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5702)
[M::mem_pestat] mean and std.dev: (794.62, 1152.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7543)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 201, 311)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 659)
[M::mem_pestat] mean and std.dev: (233.73, 125.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 833)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (418, 611, 999)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2161)
[M::mem_pestat] mean and std.dev: (650.18, 431.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2742)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 248, 745)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1869)
[M::mem_pestat] mean and std.dev: (349.95, 298.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2431)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 718654 sequences (100000092 bp) in 2.161 CPU sec, 2.171 real sec...
[M::mem_process_seqs] Processed 717212 reads in 211.792 CPU sec, 6.747 real sec
sorting block 14, #reads = 1091040 mem = 536879521 peak = 839811072
[M::mem_process_seqs] Processed 718194 reads in 139.679 CPU sec, 4.721 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 290271, 16, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 226, 389)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 797)
[M::mem_pestat] mean and std.dev: (258.73, 138.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1001)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 202, 311)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 657)
[M::mem_pestat] mean and std.dev: (234.41, 126.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 830)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (363, 530, 1294)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3156)
[M::mem_pestat] mean and std.dev: (602.43, 524.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4087)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (265, 411, 644)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1402)
[M::mem_pestat] mean and std.dev: (344.79, 154.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1781)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 716986 sequences (100000184 bp) in 3.042 CPU sec, 3.349 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 289824, 19, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (249, 486, 898)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2196)
[M::mem_pestat] mean and std.dev: (553.90, 376.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2845)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 200, 308)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 650)
[M::mem_pestat] mean and std.dev: (232.27, 124.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 821)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 201, 662)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1584)
[M::mem_pestat] mean and std.dev: (302.25, 225.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2045)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 251, 300)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (57, 462)
[M::mem_pestat] mean and std.dev: (235.87, 70.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 543)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 719256 sequences (100000199 bp) in 2.053 CPU sec, 2.056 real sec...
[M::mem_process_seqs] Processed 718440 reads in 216.093 CPU sec, 7.163 real sec
sorting block 15, #reads = 1092413 mem = 536882900 peak = 839811072
[M::mem_process_seqs] Processed 718654 reads in 139.354 CPU sec, 4.438 real sec
sorting block 16, #reads = 1090977 mem = 536878113 peak = 839811072
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 289621, 7, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 362, 912)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2298)
[M::mem_pestat] mean and std.dev: (599.12, 564.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2991)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (139, 203, 315)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 667)
[M::mem_pestat] mean and std.dev: (236.72, 127.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 843)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 241, 550)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1264)
[M::mem_pestat] mean and std.dev: (369.66, 271.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1621)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 718956 sequences (100000113 bp) in 3.261 CPU sec, 3.473 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 290545, 24, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 315, 782)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2042)
[M::mem_pestat] mean and std.dev: (470.87, 479.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2672)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 199, 306)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 644)
[M::mem_pestat] mean and std.dev: (230.64, 123.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 813)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (599, 2371, 3253)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8561)
[M::mem_pestat] mean and std.dev: (1843.05, 1649.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11215)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 257, 753)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1861)
[M::mem_pestat] mean and std.dev: (536.55, 571.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2824)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 718116 sequences (100000149 bp) in 2.358 CPU sec, 2.368 real sec...
[M::mem_process_seqs] Processed 716986 reads in 215.740 CPU sec, 6.957 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (19, 289950, 14, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 247, 1458)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3976)
[M::mem_pestat] mean and std.dev: (533.24, 553.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5235)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 200, 307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 647)
[M::mem_pestat] mean and std.dev: (231.58, 123.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 817)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (282, 424, 1076)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2664)
[M::mem_pestat] mean and std.dev: (527.54, 397.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3458)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (273, 416, 722)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1620)
[M::mem_pestat] mean and std.dev: (495.44, 346.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2069)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 718956 reads in 118.578 CPU sec, 3.821 real sec
[M::process] read 714456 sequences (100000212 bp) in 3.211 CPU sec, 3.222 real sec...
sorting block 17, #reads = 1091749 mem = 536877944 peak = 839811072
[M::mem_process_seqs] Processed 719256 reads in 303.608 CPU sec, 9.720 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 289631, 19, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 447, 1741)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4851)
[M::mem_pestat] mean and std.dev: (780.21, 751.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6406)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 201, 309)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 651)
[M::mem_pestat] mean and std.dev: (232.81, 124.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 822)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (342, 974, 1337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3327)
[M::mem_pestat] mean and std.dev: (1031.74, 808.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4322)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 294, 4676)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13586)
[M::mem_pestat] mean and std.dev: (1809.73, 2731.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 18041)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 18, #reads = 1091642 mem = 536884514 peak = 840273920
[M::process] read 717684 sequences (100000205 bp) in 3.174 CPU sec, 3.643 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 288992, 12, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 287, 440)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 930)
[M::mem_pestat] mean and std.dev: (282.73, 117.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1175)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (141, 208, 319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 675)
[M::mem_pestat] mean and std.dev: (240.32, 128.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 853)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 694, 1494)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4128)
[M::mem_pestat] mean and std.dev: (945.42, 1012.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5445)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 316, 835)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2071)
[M::mem_pestat] mean and std.dev: (403.61, 300.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2689)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 718116 reads in 235.405 CPU sec, 7.462 real sec
[M::process] read 717272 sequences (100000238 bp) in 2.344 CPU sec, 2.408 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 289618, 15, 18)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 289, 570)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1380)
[M::mem_pestat] mean and std.dev: (340.11, 257.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1785)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 201, 307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 645)
[M::mem_pestat] mean and std.dev: (231.97, 123.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 814)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (771, 1353, 1415)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2703)
[M::mem_pestat] mean and std.dev: (930.00, 681.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3655)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 312, 463)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1067)
[M::mem_pestat] mean and std.dev: (367.35, 296.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1553)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 718520 sequences (100000005 bp) in 2.714 CPU sec, 2.718 real sec...
[M::mem_process_seqs] Processed 717684 reads in 119.833 CPU sec, 3.794 real sec
sorting block 19, #reads = 1090888 mem = 536879081 peak = 840273920
[M::mem_process_seqs] Processed 714456 reads in 300.325 CPU sec, 9.526 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 289300, 21, 24)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 264, 400)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 866)
[M::mem_pestat] mean and std.dev: (263.34, 137.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1099)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 201, 307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 645)
[M::mem_pestat] mean and std.dev: (231.86, 122.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 814)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 472, 1439)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3883)
[M::mem_pestat] mean and std.dev: (730.26, 747.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5105)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 386, 734)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1852)
[M::mem_pestat] mean and std.dev: (551.17, 484.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2491)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 20, #reads = 1090414 mem = 536881518 peak = 840273920
[M::process] read 717690 sequences (100000010 bp) in 3.466 CPU sec, 3.750 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 289969, 18, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 361, 1207)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3267)
[M::mem_pestat] mean and std.dev: (651.54, 613.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4297)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 198, 304)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 638)
[M::mem_pestat] mean and std.dev: (229.77, 122.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 805)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (123, 782, 2439)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7071)
[M::mem_pestat] mean and std.dev: (1079.06, 1106.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9387)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (230, 442, 608)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1364)
[M::mem_pestat] mean and std.dev: (409.32, 230.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1742)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 717272 reads in 240.098 CPU sec, 7.638 real sec
[M::process] read 714616 sequences (100000278 bp) in 2.568 CPU sec, 2.637 real sec...
[M::mem_process_seqs] Processed 718520 reads in 147.654 CPU sec, 4.723 real sec
sorting block 21, #reads = 1088689 mem = 536878035 peak = 840273920
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 289270, 14, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 347, 569)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1363)
[M::mem_pestat] mean and std.dev: (350.49, 219.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1760)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 200, 303)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 633)
[M::mem_pestat] mean and std.dev: (229.44, 120.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 798)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 692, 1885)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5315)
[M::mem_pestat] mean and std.dev: (1079.14, 1045.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7030)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 395, 612)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1430)
[M::mem_pestat] mean and std.dev: (404.11, 247.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1839)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 717578 sequences (100000216 bp) in 2.976 CPU sec, 3.215 real sec...
[M::process] read 717678 sequences (100000148 bp) in 1.747 CPU sec, 1.754 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 288398, 19, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 209, 1299)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3597)
[M::mem_pestat] mean and std.dev: (477.61, 504.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4746)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (141, 207, 316)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 666)
[M::mem_pestat] mean and std.dev: (238.11, 126.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 841)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 192, 1395)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3801)
[M::mem_pestat] mean and std.dev: (766.58, 813.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5004)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 440, 733)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1787)
[M::mem_pestat] mean and std.dev: (488.79, 350.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2314)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 717690 reads in 220.038 CPU sec, 7.086 real sec
[M::mem_process_seqs] Processed 714616 reads in 141.759 CPU sec, 4.633 real sec
sorting block 22, #reads = 1089802 mem = 536884770 peak = 840273920
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 289843, 27, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 504, 1672)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4620)
[M::mem_pestat] mean and std.dev: (882.86, 1143.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6094)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 199, 303)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 633)
[M::mem_pestat] mean and std.dev: (229.56, 120.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 798)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (227, 662, 1186)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3104)
[M::mem_pestat] mean and std.dev: (832.04, 639.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4063)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 276, 1267)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3403)
[M::mem_pestat] mean and std.dev: (597.30, 601.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4471)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 718054 sequences (100000216 bp) in 3.371 CPU sec, 3.577 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 289818, 19, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 284, 564)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1350)
[M::mem_pestat] mean and std.dev: (410.35, 393.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1983)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 200, 304)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 636)
[M::mem_pestat] mean and std.dev: (230.24, 121.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 802)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1215, 1452, 2585)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5325)
[M::mem_pestat] mean and std.dev: (1658.11, 1282.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6788)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 273, 349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 603)
[M::mem_pestat] mean and std.dev: (276.55, 96.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 730)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 718510 sequences (100000186 bp) in 2.277 CPU sec, 2.280 real sec...
[M::mem_process_seqs] Processed 717578 reads in 220.363 CPU sec, 7.120 real sec
sorting block 23, #reads = 1087976 mem = 536879402 peak = 840273920
[M::mem_process_seqs] Processed 717678 reads in 142.204 CPU sec, 4.610 real sec
sorting block 24, #reads = 1089793 mem = 536878096 peak = 840273920
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 289406, 7, 21)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 346, 1427)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3837)
[M::mem_pestat] mean and std.dev: (736.46, 842.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5042)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 200, 304)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 638)
[M::mem_pestat] mean and std.dev: (229.78, 120.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 805)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 316, 812)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2070)
[M::mem_pestat] mean and std.dev: (386.47, 333.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2699)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 718026 sequences (100000169 bp) in 3.289 CPU sec, 3.508 real sec...
[M::process] read 720538 sequences (100000231 bp) in 2.001 CPU sec, 2.008 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 290021, 25, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 331, 570)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1358)
[M::mem_pestat] mean and std.dev: (331.95, 226.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1752)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 199, 304)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 638)
[M::mem_pestat] mean and std.dev: (229.98, 122.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 805)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 1193, 1392)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3794)
[M::mem_pestat] mean and std.dev: (914.17, 804.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4995)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (245, 398, 963)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2399)
[M::mem_pestat] mean and std.dev: (451.63, 313.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3117)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 718054 reads in 226.450 CPU sec, 7.333 real sec
[M::mem_process_seqs] Processed 718510 reads in 144.546 CPU sec, 4.624 real sec
sorting block 25, #reads = 1088844 mem = 536877510 peak = 840273920
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 289520, 17, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (254, 363, 598)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1286)
[M::mem_pestat] mean and std.dev: (386.12, 219.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1630)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 200, 305)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 639)
[M::mem_pestat] mean and std.dev: (230.60, 122.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 806)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (345, 983, 983)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2259)
[M::mem_pestat] mean and std.dev: (670.40, 406.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2897)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 301, 1832)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5090)
[M::mem_pestat] mean and std.dev: (900.16, 1165.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6719)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 719684 sequences (100000143 bp) in 3.334 CPU sec, 3.506 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 290274, 14, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 371, 1276)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3506)
[M::mem_pestat] mean and std.dev: (545.11, 483.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4621)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 197, 300)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 630)
[M::mem_pestat] mean and std.dev: (227.11, 119.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 795)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (43, 187, 743)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2143)
[M::mem_pestat] mean and std.dev: (376.64, 425.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2843)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 284, 445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 925)
[M::mem_pestat] mean and std.dev: (295.57, 128.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1165)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 718388 sequences (100000234 bp) in 2.154 CPU sec, 2.161 real sec...
[M::mem_process_seqs] Processed 718026 reads in 226.060 CPU sec, 7.225 real sec
[M::mem_process_seqs] Processed 720538 reads in 147.330 CPU sec, 4.720 real sec
sorting block 26, #reads = 1089442 mem = 536877116 peak = 840273920
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 290370, 31, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 202, 436)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 922)
[M::mem_pestat] mean and std.dev: (235.24, 106.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1165)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 198, 303)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 637)
[M::mem_pestat] mean and std.dev: (228.98, 121.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 804)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (307, 887, 2386)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6544)
[M::mem_pestat] mean and std.dev: (1161.16, 909.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8623)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 284, 941)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2413)
[M::mem_pestat] mean and std.dev: (525.62, 563.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3149)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 717782 sequences (100000181 bp) in 3.339 CPU sec, 3.597 real sec...
[M::process] read 714854 sequences (100000017 bp) in 2.105 CPU sec, 2.112 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 289873, 8, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (127, 230, 255)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 511)
[M::mem_pestat] mean and std.dev: (200.86, 92.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 639)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 201, 307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 645)
[M::mem_pestat] mean and std.dev: (231.84, 122.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 814)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 289, 563)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1283)
[M::mem_pestat] mean and std.dev: (341.47, 210.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1643)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 719684 reads in 225.853 CPU sec, 7.236 real sec
sorting block 27, #reads = 1089068 mem = 536880966 peak = 840273920
[M::mem_process_seqs] Processed 718388 reads in 144.480 CPU sec, 4.606 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 289696, 24, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 398, 688)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1642)
[M::mem_pestat] mean and std.dev: (442.25, 284.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2119)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 201, 311)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 657)
[M::mem_pestat] mean and std.dev: (234.54, 125.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 830)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (320, 494, 2160)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5840)
[M::mem_pestat] mean and std.dev: (1367.79, 1584.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7707)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 408, 625)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1465)
[M::mem_pestat] mean and std.dev: (419.48, 280.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1885)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 28, #reads = 1090604 mem = 536876117 peak = 840273920
[M::process] read 719606 sequences (100000123 bp) in 3.189 CPU sec, 3.417 real sec...
[M::process] read 719516 sequences (100000038 bp) in 1.920 CPU sec, 1.920 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 289091, 20, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 666, 3816)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 11014)
[M::mem_pestat] mean and std.dev: (1440.24, 1517.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14613)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (141, 208, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 690)
[M::mem_pestat] mean and std.dev: (242.46, 131.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 873)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (518, 1356, 2512)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6500)
[M::mem_pestat] mean and std.dev: (1491.70, 1024.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8494)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 485, 2757)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8013)
[M::mem_pestat] mean and std.dev: (1327.56, 1511.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10641)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 717782 reads in 211.961 CPU sec, 6.759 real sec
[M::mem_process_seqs] Processed 714854 reads in 147.788 CPU sec, 4.728 real sec
sorting block 29, #reads = 1089725 mem = 536877812 peak = 840273920
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 290286, 9, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 337, 468)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1054)
[M::mem_pestat] mean and std.dev: (308.45, 170.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1347)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 198, 303)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 637)
[M::mem_pestat] mean and std.dev: (229.13, 121.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 804)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 406, 1014)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2636)
[M::mem_pestat] mean and std.dev: (480.00, 384.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3447)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 719184 sequences (100000139 bp) in 3.883 CPU sec, 4.156 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 290478, 12, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 606, 1111)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3031)
[M::mem_pestat] mean and std.dev: (639.77, 638.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3991)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 199, 305)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 643)
[M::mem_pestat] mean and std.dev: (230.54, 122.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 812)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (120, 908, 2822)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8226)
[M::mem_pestat] mean and std.dev: (1278.00, 1417.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10928)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (141, 295, 813)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2157)
[M::mem_pestat] mean and std.dev: (564.47, 504.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2829)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 719606 reads in 210.658 CPU sec, 6.704 real sec
[M::process] read 718744 sequences (100000192 bp) in 2.366 CPU sec, 2.397 real sec...
[M::mem_process_seqs] Processed 719516 reads in 140.000 CPU sec, 4.550 real sec
sorting block 30, #reads = 1089380 mem = 536886984 peak = 840273920
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 290295, 25, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 252, 1040)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2732)
[M::mem_pestat] mean and std.dev: (392.23, 381.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3578)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 199, 306)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 644)
[M::mem_pestat] mean and std.dev: (231.04, 122.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 813)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (141, 261, 983)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2667)
[M::mem_pestat] mean and std.dev: (529.79, 463.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3509)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 273, 747)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1811)
[M::mem_pestat] mean and std.dev: (485.37, 448.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2343)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 718040 sequences (100000180 bp) in 3.194 CPU sec, 3.410 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 289906, 18, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (258, 534, 1048)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2628)
[M::mem_pestat] mean and std.dev: (577.81, 494.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3418)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 199, 306)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 644)
[M::mem_pestat] mean and std.dev: (231.03, 122.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 813)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (283, 449, 769)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1741)
[M::mem_pestat] mean and std.dev: (414.87, 254.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2227)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 342, 691)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1649)
[M::mem_pestat] mean and std.dev: (457.92, 335.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2128)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 714204 sequences (100000286 bp) in 2.090 CPU sec, 2.095 real sec...
[M::mem_process_seqs] Processed 719184 reads in 212.643 CPU sec, 6.904 real sec
sorting block 31, #reads = 1091627 mem = 536884737 peak = 840273920
[M::mem_process_seqs] Processed 718744 reads in 137.591 CPU sec, 4.415 real sec
sorting block 32, #reads = 1090528 mem = 536879679 peak = 840273920
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 289496, 22, 17)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (225, 265, 379)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 687)
[M::mem_pestat] mean and std.dev: (280.15, 115.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 841)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 201, 309)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 651)
[M::mem_pestat] mean and std.dev: (233.20, 124.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 822)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (229, 668, 1197)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3133)
[M::mem_pestat] mean and std.dev: (770.45, 700.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4101)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 279, 1856)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5140)
[M::mem_pestat] mean and std.dev: (763.53, 942.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6782)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 717550 sequences (100000122 bp) in 2.957 CPU sec, 3.176 real sec...
[M::process] read 717484 sequences (100000152 bp) in 1.810 CPU sec, 1.814 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 289124, 18, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 325, 1280)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3504)
[M::mem_pestat] mean and std.dev: (524.45, 595.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4616)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (142, 209, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 682)
[M::mem_pestat] mean and std.dev: (241.94, 129.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 862)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (399, 833, 1397)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3393)
[M::mem_pestat] mean and std.dev: (804.31, 747.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4391)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 486, 1076)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2804)
[M::mem_pestat] mean and std.dev: (634.00, 541.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3668)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 718040 reads in 214.167 CPU sec, 6.872 real sec
[M::mem_process_seqs] Processed 714204 reads in 137.707 CPU sec, 4.385 real sec
sorting block 33, #reads = 1089407 mem = 536881828 peak = 840273920
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 289292, 23, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (134, 206, 719)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1889)
[M::mem_pestat] mean and std.dev: (370.81, 352.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2474)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 201, 307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 645)
[M::mem_pestat] mean and std.dev: (231.85, 122.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 814)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (525, 610, 2700)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7050)
[M::mem_pestat] mean and std.dev: (1357.13, 1468.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9225)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 402, 813)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2015)
[M::mem_pestat] mean and std.dev: (408.62, 328.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2616)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 717894 sequences (100000152 bp) in 3.246 CPU sec, 3.439 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 289524, 8, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 542, 1615)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4401)
[M::mem_pestat] mean and std.dev: (1048.20, 1192.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5818)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 201, 307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 645)
[M::mem_pestat] mean and std.dev: (232.25, 123.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 814)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (234, 435, 535)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1137)
[M::mem_pestat] mean and std.dev: (340.29, 140.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1438)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 717776 sequences (100000163 bp) in 2.216 CPU sec, 2.222 real sec...
[M::mem_process_seqs] Processed 717550 reads in 217.468 CPU sec, 6.958 real sec
[M::mem_process_seqs] Processed 717484 reads in 144.236 CPU sec, 4.583 real sec
sorting block 34, #reads = 1088755 mem = 536885012 peak = 840273920
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 289475, 14, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (225, 556, 2074)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5772)
[M::mem_pestat] mean and std.dev: (1024.45, 1190.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7621)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 200, 306)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 642)
[M::mem_pestat] mean and std.dev: (231.33, 122.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 810)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (105, 2119, 4251)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12543)
[M::mem_pestat] mean and std.dev: (2286.86, 2181.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 16689)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 336, 715)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1701)
[M::mem_pestat] mean and std.dev: (406.83, 305.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2194)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 718074 sequences (100000239 bp) in 2.773 CPU sec, 2.945 real sec...
[M::process] read 718082 sequences (100000229 bp) in 2.090 CPU sec, 2.097 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 289834, 23, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 315, 1032)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2750)
[M::mem_pestat] mean and std.dev: (559.66, 519.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3609)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 199, 303)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 633)
[M::mem_pestat] mean and std.dev: (229.38, 119.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 798)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (101, 233, 657)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1769)
[M::mem_pestat] mean and std.dev: (300.53, 357.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2325)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 321, 689)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1653)
[M::mem_pestat] mean and std.dev: (365.49, 280.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2135)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 717894 reads in 215.891 CPU sec, 6.882 real sec
sorting block 35, #reads = 1089616 mem = 536879255 peak = 840273920
[M::mem_process_seqs] Processed 717776 reads in 140.842 CPU sec, 4.482 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 289400, 17, 24)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 223, 864)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2242)
[M::mem_pestat] mean and std.dev: (496.93, 498.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2931)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 199, 304)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 638)
[M::mem_pestat] mean and std.dev: (229.73, 121.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 805)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (577, 985, 2304)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5758)
[M::mem_pestat] mean and std.dev: (1314.59, 1257.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7485)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (248, 393, 435)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 809)
[M::mem_pestat] mean and std.dev: (320.59, 130.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 996)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 36, #reads = 1090429 mem = 536880487 peak = 840273920
[M::process] read 717744 sequences (100000054 bp) in 3.278 CPU sec, 3.514 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 289731, 18, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (119, 187, 418)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1016)
[M::mem_pestat] mean and std.dev: (216.86, 169.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1315)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 199, 303)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 635)
[M::mem_pestat] mean and std.dev: (229.15, 120.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 801)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (375, 734, 1001)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2253)
[M::mem_pestat] mean and std.dev: (603.60, 424.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2879)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 253, 372)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 778)
[M::mem_pestat] mean and std.dev: (279.17, 172.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 981)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 718020 sequences (100000084 bp) in 2.290 CPU sec, 2.291 real sec...
[M::mem_process_seqs] Processed 718074 reads in 215.629 CPU sec, 6.966 real sec
[M::mem_process_seqs] Processed 718082 reads in 137.285 CPU sec, 4.456 real sec
sorting block 37, #reads = 1090321 mem = 536879850 peak = 840273920
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 289889, 23, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 278, 815)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2039)
[M::mem_pestat] mean and std.dev: (489.67, 463.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2651)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 200, 304)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 636)
[M::mem_pestat] mean and std.dev: (230.31, 121.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 802)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 480, 1295)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3479)
[M::mem_pestat] mean and std.dev: (666.00, 634.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4571)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 280, 542)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1206)
[M::mem_pestat] mean and std.dev: (337.55, 207.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1538)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 718146 sequences (100000204 bp) in 3.045 CPU sec, 3.245 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 289800, 19, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 236, 993)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2633)
[M::mem_pestat] mean and std.dev: (454.02, 421.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3453)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 200, 304)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 636)
[M::mem_pestat] mean and std.dev: (230.16, 121.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 802)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (62, 241, 1244)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3608)
[M::mem_pestat] mean and std.dev: (718.53, 920.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4790)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (230, 359, 675)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1565)
[M::mem_pestat] mean and std.dev: (409.32, 260.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2010)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 718370 sequences (100000157 bp) in 2.312 CPU sec, 2.318 real sec...
[M::mem_process_seqs] Processed 717744 reads in 213.944 CPU sec, 6.900 real sec
[M::mem_process_seqs] Processed 718020 reads in 139.244 CPU sec, 4.419 real sec
sorting block 38, #reads = 1090553 mem = 536880243 peak = 840273920
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 289404, 20, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 196, 389)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 859)
[M::mem_pestat] mean and std.dev: (241.13, 140.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1094)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 199, 303)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 635)
[M::mem_pestat] mean and std.dev: (229.14, 120.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 801)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 419, 3935)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 11415)
[M::mem_pestat] mean and std.dev: (2475.95, 3556.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 16702)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 320, 700)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1734)
[M::mem_pestat] mean and std.dev: (407.23, 415.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2251)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 715542 sequences (100000079 bp) in 3.372 CPU sec, 3.605 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 289507, 21, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 411, 1188)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3152)
[M::mem_pestat] mean and std.dev: (555.96, 462.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4134)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 200, 304)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 638)
[M::mem_pestat] mean and std.dev: (230.14, 121.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 805)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 684, 2578)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7428)
[M::mem_pestat] mean and std.dev: (1365.38, 1466.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9853)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 253, 1333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3581)
[M::mem_pestat] mean and std.dev: (624.50, 824.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4705)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 715236 sequences (100000180 bp) in 2.227 CPU sec, 2.234 real sec...
[M::mem_process_seqs] Processed 718146 reads in 222.041 CPU sec, 7.189 real sec
sorting block 39, #reads = 1089691 mem = 536879686 peak = 840273920
[M::mem_process_seqs] Processed 718370 reads in 146.126 CPU sec, 4.728 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 289468, 20, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (254, 485, 5563)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 16181)
[M::mem_pestat] mean and std.dev: (2433.03, 2908.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 21490)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (140, 206, 315)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 665)
[M::mem_pestat] mean and std.dev: (237.40, 125.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 840)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (275, 737, 2695)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7535)
[M::mem_pestat] mean and std.dev: (2145.65, 2570.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12427)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (237, 996, 1594)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4308)
[M::mem_pestat] mean and std.dev: (779.42, 566.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5665)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 40, #reads = 1089686 mem = 536879027 peak = 840273920
[M::process] read 716452 sequences (100000061 bp) in 3.124 CPU sec, 3.310 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 288778, 10, 21)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 576, 1227)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3253)
[M::mem_pestat] mean and std.dev: (903.44, 892.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4472)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (140, 207, 317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 671)
[M::mem_pestat] mean and std.dev: (238.26, 126.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 848)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (399, 975, 983)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2151)
[M::mem_pestat] mean and std.dev: (633.50, 320.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2735)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 291, 552)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1268)
[M::mem_pestat] mean and std.dev: (368.80, 256.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1626)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 716658 sequences (100000029 bp) in 2.238 CPU sec, 2.239 real sec...
[M::mem_process_seqs] Processed 715542 reads in 215.728 CPU sec, 6.954 real sec
[M::mem_process_seqs] Processed 715236 reads in 139.903 CPU sec, 4.533 real sec
sorting block 41, #reads = 1089702 mem = 536879944 peak = 840273920
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 289399, 22, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 442, 890)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2232)
[M::mem_pestat] mean and std.dev: (539.75, 604.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2958)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (139, 203, 311)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 655)
[M::mem_pestat] mean and std.dev: (234.53, 123.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 827)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (80, 404, 558)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1514)
[M::mem_pestat] mean and std.dev: (376.05, 304.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1992)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 250, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 611)
[M::mem_pestat] mean and std.dev: (243.16, 59.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 746)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 714366 sequences (100000042 bp) in 3.254 CPU sec, 3.451 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (22, 289605, 7, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (132, 412, 1932)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5532)
[M::mem_pestat] mean and std.dev: (591.41, 698.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7332)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (139, 205, 314)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 664)
[M::mem_pestat] mean and std.dev: (236.29, 125.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 839)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 262, 580)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1362)
[M::mem_pestat] mean and std.dev: (282.71, 172.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1753)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 719174 sequences (100000049 bp) in 2.293 CPU sec, 2.295 real sec...
[M::mem_process_seqs] Processed 716452 reads in 215.728 CPU sec, 6.970 real sec
[M::mem_process_seqs] Processed 716658 reads in 138.511 CPU sec, 4.405 real sec
sorting block 42, #reads = 1090246 mem = 536883840 peak = 840273920
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 288932, 10, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 321, 1055)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2871)
[M::mem_pestat] mean and std.dev: (763.82, 913.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4420)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (141, 210, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 690)
[M::mem_pestat] mean and std.dev: (243.29, 131.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 873)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 722, 1053)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2743)
[M::mem_pestat] mean and std.dev: (706.00, 618.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3588)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 349, 1378)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3694)
[M::mem_pestat] mean and std.dev: (738.25, 785.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4852)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 719898 sequences (100000175 bp) in 3.297 CPU sec, 3.474 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 290735, 20, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 376, 2096)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5846)
[M::mem_pestat] mean and std.dev: (1176.90, 1275.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7721)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 199, 306)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 644)
[M::mem_pestat] mean and std.dev: (230.94, 123.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 813)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (58, 535, 1328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3868)
[M::mem_pestat] mean and std.dev: (619.95, 598.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5138)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 324, 813)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2121)
[M::mem_pestat] mean and std.dev: (490.55, 496.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2775)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 719474 sequences (100000219 bp) in 2.315 CPU sec, 2.321 real sec...
[M::mem_process_seqs] Processed 714366 reads in 215.776 CPU sec, 6.882 real sec
sorting block 43, #reads = 1091055 mem = 536878815 peak = 840273920
[M::mem_process_seqs] Processed 719174 reads in 140.035 CPU sec, 4.522 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 290500, 31, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 440, 825)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2063)
[M::mem_pestat] mean and std.dev: (418.70, 377.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2682)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 197, 303)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 637)
[M::mem_pestat] mean and std.dev: (228.66, 121.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 804)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (407, 798, 2041)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5309)
[M::mem_pestat] mean and std.dev: (1428.97, 1485.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7373)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (242, 409, 2624)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7388)
[M::mem_pestat] mean and std.dev: (1249.47, 1497.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9770)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 44, #reads = 1091215 mem = 536876850 peak = 840273920
[M::process] read 719714 sequences (100000031 bp) in 3.337 CPU sec, 3.517 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 290608, 21, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 294, 487)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1063)
[M::mem_pestat] mean and std.dev: (299.65, 172.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1351)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 198, 303)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 637)
[M::mem_pestat] mean and std.dev: (228.95, 120.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 804)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 375, 1977)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5617)
[M::mem_pestat] mean and std.dev: (665.16, 861.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7437)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (340, 516, 724)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1492)
[M::mem_pestat] mean and std.dev: (413.64, 177.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1876)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 718064 sequences (100000034 bp) in 2.319 CPU sec, 2.323 real sec...
[M::mem_process_seqs] Processed 719898 reads in 220.054 CPU sec, 7.104 real sec
[M::mem_process_seqs] Processed 719474 reads in 141.069 CPU sec, 4.550 real sec
sorting block 45, #reads = 1091788 mem = 536880091 peak = 840273920
[M::process] read 716576 sequences (100000052 bp) in 3.274 CPU sec, 3.450 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 290245, 20, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (233, 465, 1149)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2981)
[M::mem_pestat] mean and std.dev: (730.21, 568.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3897)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 201, 308)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 648)
[M::mem_pestat] mean and std.dev: (232.74, 124.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 818)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (598, 1134, 1755)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4069)
[M::mem_pestat] mean and std.dev: (947.29, 633.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5226)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 378, 529)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1241)
[M::mem_pestat] mean and std.dev: (354.28, 219.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1597)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 718864 sequences (100000260 bp) in 2.307 CPU sec, 2.314 real sec...
[M::mem_process_seqs] Processed 718064 reads in 124.395 CPU sec, 3.932 real sec
sorting block 46, #reads = 1092675 mem = 536876262 peak = 840273920
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 290825, 20, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 475, 1484)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4148)
[M::mem_pestat] mean and std.dev: (749.87, 708.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5480)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 197, 303)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 637)
[M::mem_pestat] mean and std.dev: (228.74, 121.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 804)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (295, 585, 678)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1444)
[M::mem_pestat] mean and std.dev: (491.40, 341.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1859)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 240, 421)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 959)
[M::mem_pestat] mean and std.dev: (279.61, 190.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1228)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 289651, 25, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 411, 942)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2378)
[M::mem_pestat] mean and std.dev: (562.55, 467.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3096)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (139, 204, 314)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 664)
[M::mem_pestat] mean and std.dev: (236.57, 126.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 839)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (99, 500, 1137)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3213)
[M::mem_pestat] mean and std.dev: (564.64, 515.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4251)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 356, 537)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1171)
[M::mem_pestat] mean and std.dev: (329.46, 178.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1488)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 719714 reads in 331.805 CPU sec, 10.650 real sec
[M::process] read 716950 sequences (100000119 bp) in 2.686 CPU sec, 2.719 real sec...
[M::mem_process_seqs] Processed 716576 reads in 162.434 CPU sec, 5.186 real sec
sorting block 47, #reads = 1090845 mem = 536880470 peak = 840273920
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 290141, 16, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (142, 174, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 736)
[M::mem_pestat] mean and std.dev: (193.26, 125.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 934)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 199, 305)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 641)
[M::mem_pestat] mean and std.dev: (230.39, 122.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 809)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (696, 866, 3443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8937)
[M::mem_pestat] mean and std.dev: (1724.00, 1733.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11684)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (241, 716, 1690)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4588)
[M::mem_pestat] mean and std.dev: (826.74, 660.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6037)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 717748 sequences (100000190 bp) in 3.465 CPU sec, 3.657 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 289456, 17, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 319, 606)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1474)
[M::mem_pestat] mean and std.dev: (346.05, 279.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1908)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (139, 203, 312)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 658)
[M::mem_pestat] mean and std.dev: (235.68, 126.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 831)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (675, 944, 5424)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 14922)
[M::mem_pestat] mean and std.dev: (2467.88, 2250.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 19671)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (248, 299, 757)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1775)
[M::mem_pestat] mean and std.dev: (426.51, 293.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2284)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 717944 sequences (100000096 bp) in 2.197 CPU sec, 2.199 real sec...
[M::mem_process_seqs] Processed 718864 reads in 221.232 CPU sec, 7.061 real sec
[M::mem_process_seqs] Processed 716950 reads in 142.028 CPU sec, 4.504 real sec
sorting block 48, #reads = 1090954 mem = 536876970 peak = 840273920
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 289619, 29, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 284, 408)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 916)
[M::mem_pestat] mean and std.dev: (239.83, 118.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1170)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 201, 307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 645)
[M::mem_pestat] mean and std.dev: (232.09, 122.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 814)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 783, 2081)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5863)
[M::mem_pestat] mean and std.dev: (1092.24, 1182.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7754)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (264, 342, 1933)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5271)
[M::mem_pestat] mean and std.dev: (860.39, 817.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6940)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 718202 sequences (100000074 bp) in 3.644 CPU sec, 3.896 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 290000, 25, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 291, 1084)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2874)
[M::mem_pestat] mean and std.dev: (598.87, 657.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3769)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 199, 303)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 633)
[M::mem_pestat] mean and std.dev: (229.67, 120.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 798)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (134, 544, 2709)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7859)
[M::mem_pestat] mean and std.dev: (1356.48, 1856.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10434)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 335, 1055)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2745)
[M::mem_pestat] mean and std.dev: (544.12, 501.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3590)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 718292 sequences (100000203 bp) in 2.339 CPU sec, 2.344 real sec...
[M::mem_process_seqs] Processed 717748 reads in 226.725 CPU sec, 7.279 real sec
sorting block 49, #reads = 1090166 mem = 536878834 peak = 840273920
[M::mem_process_seqs] Processed 717944 reads in 148.305 CPU sec, 4.799 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 289908, 22, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 457, 1574)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4398)
[M::mem_pestat] mean and std.dev: (1049.67, 1451.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6855)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 198, 302)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 630)
[M::mem_pestat] mean and std.dev: (228.96, 120.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 794)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (362, 678, 1005)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2291)
[M::mem_pestat] mean and std.dev: (676.62, 459.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2934)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 459, 954)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2456)
[M::mem_pestat] mean and std.dev: (559.84, 495.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3207)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 718040 sequences (100000028 bp) in 2.996 CPU sec, 3.209 real sec...
sorting block 50, #reads = 1089072 mem = 536882039 peak = 840273920
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 289861, 27, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 621, 1007)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2579)
[M::mem_pestat] mean and std.dev: (554.27, 374.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3365)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 198, 301)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 629)
[M::mem_pestat] mean and std.dev: (228.39, 119.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 793)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (608, 1115, 2897)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7475)
[M::mem_pestat] mean and std.dev: (1592.54, 1485.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9764)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 250, 615)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1461)
[M::mem_pestat] mean and std.dev: (370.26, 308.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1884)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 717872 sequences (100000006 bp) in 2.393 CPU sec, 2.394 real sec...
[M::mem_process_seqs] Processed 718202 reads in 227.028 CPU sec, 7.341 real sec
[M::mem_process_seqs] Processed 718292 reads in 145.186 CPU sec, 4.713 real sec
sorting block 51, #reads = 1088740 mem = 536879300 peak = 840273920
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 289689, 18, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 231, 408)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 870)
[M::mem_pestat] mean and std.dev: (266.21, 133.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1101)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 199, 303)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 633)
[M::mem_pestat] mean and std.dev: (229.61, 120.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 798)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (532, 682, 2050)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5086)
[M::mem_pestat] mean and std.dev: (971.75, 988.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6604)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (280, 646, 1293)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3319)
[M::mem_pestat] mean and std.dev: (740.81, 547.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4332)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 719210 sequences (100000009 bp) in 3.383 CPU sec, 3.593 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 289759, 27, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (120, 194, 528)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1344)
[M::mem_pestat] mean and std.dev: (271.61, 201.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1752)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 199, 304)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 636)
[M::mem_pestat] mean and std.dev: (230.14, 121.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 802)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (456, 679, 1388)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3252)
[M::mem_pestat] mean and std.dev: (1052.22, 1072.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5341)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 352, 662)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1580)
[M::mem_pestat] mean and std.dev: (469.84, 375.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2039)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724474 sequences (100000139 bp) in 2.429 CPU sec, 2.435 real sec...
[M::mem_process_seqs] Processed 718040 reads in 224.409 CPU sec, 7.249 real sec
[M::mem_process_seqs] Processed 717872 reads in 144.216 CPU sec, 4.585 real sec
sorting block 52, #reads = 1089822 mem = 536880687 peak = 840273920
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 290160, 17, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (136, 207, 704)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1840)
[M::mem_pestat] mean and std.dev: (318.29, 281.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2408)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 197, 299)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 625)
[M::mem_pestat] mean and std.dev: (226.84, 119.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 788)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (51, 760, 1147)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3339)
[M::mem_pestat] mean and std.dev: (780.44, 772.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4435)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 246, 557)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1337)
[M::mem_pestat] mean and std.dev: (330.54, 244.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1727)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720228 sequences (100000300 bp) in 3.019 CPU sec, 3.175 real sec...
[M::process] read 723260 sequences (100000082 bp) in 2.169 CPU sec, 2.173 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 291988, 19, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 397, 1533)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4241)
[M::mem_pestat] mean and std.dev: (570.51, 617.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5595)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 188, 286)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 594)
[M::mem_pestat] mean and std.dev: (217.65, 114.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 748)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 395, 687)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1737)
[M::mem_pestat] mean and std.dev: (536.00, 560.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2777)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 412, 1018)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2614)
[M::mem_pestat] mean and std.dev: (511.73, 367.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3412)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 719210 reads in 236.493 CPU sec, 7.557 real sec
sorting block 53, #reads = 1088954 mem = 536878836 peak = 840273920
[M::mem_process_seqs] Processed 724474 reads in 156.568 CPU sec, 4.980 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 291226, 26, 10)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (239, 603, 1547)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4163)
[M::mem_pestat] mean and std.dev: (799.31, 797.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5471)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 195, 303)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 639)
[M::mem_pestat] mean and std.dev: (229.16, 124.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 807)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (409, 732, 2435)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6487)
[M::mem_pestat] mean and std.dev: (1485.19, 1464.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8513)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 260, 1707)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4749)
[M::mem_pestat] mean and std.dev: (872.00, 1061.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6270)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 54, #reads = 1089730 mem = 536876658 peak = 840273920
[M::process] read 723610 sequences (100000117 bp) in 2.791 CPU sec, 2.986 real sec...
[M::process] read 723014 sequences (100000188 bp) in 1.936 CPU sec, 1.942 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 292198, 23, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 220, 1084)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2950)
[M::mem_pestat] mean and std.dev: (561.17, 570.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3883)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 190, 291)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 607)
[M::mem_pestat] mean and std.dev: (221.22, 117.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 765)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 400, 839)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2123)
[M::mem_pestat] mean and std.dev: (434.29, 305.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2765)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (233, 357, 1393)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3713)
[M::mem_pestat] mean and std.dev: (687.96, 792.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4873)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 720228 reads in 232.902 CPU sec, 7.479 real sec
[M::mem_process_seqs] Processed 723260 reads in 150.379 CPU sec, 4.858 real sec
sorting block 55, #reads = 1089946 mem = 536880410 peak = 840273920
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 292473, 16, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (145, 241, 803)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2119)
[M::mem_pestat] mean and std.dev: (382.61, 389.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2777)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 190, 291)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 607)
[M::mem_pestat] mean and std.dev: (220.70, 117.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 765)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (470, 653, 2669)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7067)
[M::mem_pestat] mean and std.dev: (1370.62, 1464.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9266)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 252, 659)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1591)
[M::mem_pestat] mean and std.dev: (384.92, 291.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2057)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 719922 sequences (100000263 bp) in 3.429 CPU sec, 3.576 real sec...
[M::process] read 724694 sequences (100000110 bp) in 2.397 CPU sec, 2.399 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 292171, 15, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 294, 1108)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2964)
[M::mem_pestat] mean and std.dev: (670.17, 744.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3892)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 191, 293)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 613)
[M::mem_pestat] mean and std.dev: (222.51, 118.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 773)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (282, 549, 742)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1662)
[M::mem_pestat] mean and std.dev: (393.25, 243.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2122)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 441, 901)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2251)
[M::mem_pestat] mean and std.dev: (534.33, 379.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2926)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 723610 reads in 232.131 CPU sec, 7.461 real sec
[M::mem_process_seqs] Processed 723014 reads in 148.649 CPU sec, 4.818 real sec
sorting block 56, #reads = 1091667 mem = 536880724 peak = 840273920
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 290742, 9, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 265, 317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 593)
[M::mem_pestat] mean and std.dev: (250.45, 115.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 731)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 197, 306)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 646)
[M::mem_pestat] mean and std.dev: (231.02, 124.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 816)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 399, 589)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1331)
[M::mem_pestat] mean and std.dev: (378.35, 215.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1702)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 723464 sequences (100000052 bp) in 3.237 CPU sec, 3.403 real sec...
[M::process] read 721834 sequences (100000065 bp) in 2.213 CPU sec, 2.216 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 292777, 15, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 521, 846)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2134)
[M::mem_pestat] mean and std.dev: (545.96, 437.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2778)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 188, 286)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 594)
[M::mem_pestat] mean and std.dev: (217.85, 114.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 748)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (111, 385, 883)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2427)
[M::mem_pestat] mean and std.dev: (388.46, 322.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3199)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 475, 1148)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3054)
[M::mem_pestat] mean and std.dev: (834.48, 858.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4268)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 719922 reads in 230.286 CPU sec, 7.420 real sec
sorting block 57, #reads = 1091889 mem = 536879835 peak = 840273920
[M::mem_process_seqs] Processed 724694 reads in 150.594 CPU sec, 4.784 real sec
sorting block 58, #reads = 1091577 mem = 536880109 peak = 840273920
[M::process] read 718808 sequences (100000089 bp) in 2.699 CPU sec, 2.808 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 292508, 16, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 288, 773)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1877)
[M::mem_pestat] mean and std.dev: (486.17, 401.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2429)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 190, 290)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 604)
[M::mem_pestat] mean and std.dev: (220.40, 116.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 761)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 1752, 5697)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 16781)
[M::mem_pestat] mean and std.dev: (2640.94, 2576.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 22323)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 266, 1031)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2687)
[M::mem_pestat] mean and std.dev: (493.41, 571.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3515)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 723464 reads in 130.466 CPU sec, 4.333 real sec
[M::process] read 721996 sequences (100000068 bp) in 2.959 CPU sec, 3.182 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 291063, 14, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 380, 1163)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3099)
[M::mem_pestat] mean and std.dev: (586.72, 596.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4067)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 193, 295)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 617)
[M::mem_pestat] mean and std.dev: (223.94, 118.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 778)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (386, 749, 3527)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9809)
[M::mem_pestat] mean and std.dev: (1742.85, 2017.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12950)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 287, 1139)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3039)
[M::mem_pestat] mean and std.dev: (578.66, 644.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3989)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 718324 sequences (100000080 bp) in 2.162 CPU sec, 2.164 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 289973, 16, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 370, 1554)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4354)
[M::mem_pestat] mean and std.dev: (747.56, 981.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5754)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 199, 308)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 650)
[M::mem_pestat] mean and std.dev: (232.95, 126.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 821)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 279, 858)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2112)
[M::mem_pestat] mean and std.dev: (349.00, 230.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2739)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (269, 506, 955)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2327)
[M::mem_pestat] mean and std.dev: (628.39, 516.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3013)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 721834 reads in 256.578 CPU sec, 8.207 real sec
sorting block 59, #reads = 1092147 mem = 536880299 peak = 840273920
[M::mem_process_seqs] Processed 718808 reads in 276.088 CPU sec, 8.976 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 290880, 12, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (230, 356, 630)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1430)
[M::mem_pestat] mean and std.dev: (404.12, 262.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1830)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 194, 296)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 620)
[M::mem_pestat] mean and std.dev: (224.56, 119.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 782)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (82, 356, 2305)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6751)
[M::mem_pestat] mean and std.dev: (1096.42, 1284.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8974)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (305, 377, 1054)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2552)
[M::mem_pestat] mean and std.dev: (586.06, 512.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3301)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 60, #reads = 1088631 mem = 536878146 peak = 840273920
[M::process] read 718826 sequences (100000082 bp) in 3.231 CPU sec, 3.446 real sec...
[M::process] read 717698 sequences (100000244 bp) in 2.357 CPU sec, 2.360 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 289817, 23, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 253, 374)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 782)
[M::mem_pestat] mean and std.dev: (235.35, 117.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 986)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 200, 307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 647)
[M::mem_pestat] mean and std.dev: (232.17, 124.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 817)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (80, 438, 1250)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3590)
[M::mem_pestat] mean and std.dev: (665.96, 672.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4760)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 376, 780)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1950)
[M::mem_pestat] mean and std.dev: (481.44, 361.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2535)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 721996 reads in 232.678 CPU sec, 7.526 real sec
[M::mem_process_seqs] Processed 718324 reads in 150.194 CPU sec, 4.809 real sec
sorting block 61, #reads = 1088276 mem = 536881880 peak = 840273920
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 289941, 23, 24)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 274, 371)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 769)
[M::mem_pestat] mean and std.dev: (264.18, 129.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 968)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 198, 302)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 632)
[M::mem_pestat] mean and std.dev: (229.18, 121.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 797)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (661, 1214, 2866)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7276)
[M::mem_pestat] mean and std.dev: (1428.43, 1102.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9481)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 311, 1100)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2858)
[M::mem_pestat] mean and std.dev: (409.10, 367.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3737)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 718378 sequences (100000060 bp) in 3.264 CPU sec, 3.471 real sec...
[M::process] read 719148 sequences (100000100 bp) in 2.370 CPU sec, 2.371 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 289531, 21, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 378, 930)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2370)
[M::mem_pestat] mean and std.dev: (596.55, 517.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3090)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 200, 307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 645)
[M::mem_pestat] mean and std.dev: (232.30, 124.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 814)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (244, 453, 646)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1450)
[M::mem_pestat] mean and std.dev: (348.67, 220.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1852)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 308, 943)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2419)
[M::mem_pestat] mean and std.dev: (507.46, 422.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3157)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 718826 reads in 231.386 CPU sec, 7.402 real sec
[M::mem_process_seqs] Processed 717698 reads in 148.965 CPU sec, 4.840 real sec
sorting block 62, #reads = 1087520 mem = 536879821 peak = 840273920
[M::process] read 717900 sequences (100000275 bp) in 3.187 CPU sec, 3.370 real sec...
[M::process] read 719256 sequences (100000153 bp) in 2.225 CPU sec, 2.232 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 290101, 22, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 262, 711)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1797)
[M::mem_pestat] mean and std.dev: (397.33, 367.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2340)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 196, 299)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 623)
[M::mem_pestat] mean and std.dev: (226.62, 118.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 785)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (233, 715, 1064)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2726)
[M::mem_pestat] mean and std.dev: (631.45, 400.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3557)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 709, 1810)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5044)
[M::mem_pestat] mean and std.dev: (926.86, 835.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6661)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 719148 reads in 124.382 CPU sec, 4.014 real sec
sorting block 63, #reads = 1086969 mem = 536881277 peak = 840273920
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 289882, 20, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 350, 1284)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3514)
[M::mem_pestat] mean and std.dev: (872.26, 1021.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4960)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 198, 304)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 638)
[M::mem_pestat] mean and std.dev: (230.64, 122.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 805)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 875, 1879)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5189)
[M::mem_pestat] mean and std.dev: (981.05, 834.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6844)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 338, 1156)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3128)
[M::mem_pestat] mean and std.dev: (714.61, 818.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4114)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 290137, 17, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 365, 1366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3742)
[M::mem_pestat] mean and std.dev: (692.73, 675.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4930)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 200, 306)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 642)
[M::mem_pestat] mean and std.dev: (231.56, 123.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 810)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (478, 1030, 2505)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6559)
[M::mem_pestat] mean and std.dev: (1337.94, 1249.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8586)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (230, 335, 518)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1094)
[M::mem_pestat] mean and std.dev: (331.62, 180.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1382)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 717516 sequences (100000026 bp) in 2.484 CPU sec, 2.494 real sec...
[M::mem_process_seqs] Processed 718378 reads in 357.868 CPU sec, 11.563 real sec
[M::mem_process_seqs] Processed 717900 reads in 172.793 CPU sec, 5.678 real sec
sorting block 64, #reads = 1087547 mem = 536882312 peak = 840273920
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 289775, 19, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 360, 906)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2336)
[M::mem_pestat] mean and std.dev: (520.91, 539.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3051)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 196, 301)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 631)
[M::mem_pestat] mean and std.dev: (227.89, 121.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 796)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (68, 748, 1733)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5063)
[M::mem_pestat] mean and std.dev: (894.76, 927.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6728)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 589, 885)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2319)
[M::mem_pestat] mean and std.dev: (530.90, 493.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3036)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 728168 sequences (100000152 bp) in 3.109 CPU sec, 3.305 real sec...
[M::process] read 725780 sequences (100000291 bp) in 2.139 CPU sec, 2.150 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 289843, 18, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 464, 738)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1860)
[M::mem_pestat] mean and std.dev: (481.48, 409.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2421)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 200, 307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 645)
[M::mem_pestat] mean and std.dev: (232.56, 124.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 814)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (70, 331, 809)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2287)
[M::mem_pestat] mean and std.dev: (506.44, 541.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3026)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 353, 817)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2187)
[M::mem_pestat] mean and std.dev: (424.06, 424.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2872)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 719256 reads in 232.623 CPU sec, 7.510 real sec
sorting block 65, #reads = 1088055 mem = 536876909 peak = 840273920
[M::mem_process_seqs] Processed 717516 reads in 151.635 CPU sec, 4.825 real sec
sorting block 66, #reads = 1086326 mem = 536879921 peak = 840273920
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 293439, 14, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (139, 254, 924)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2494)
[M::mem_pestat] mean and std.dev: (529.78, 624.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3279)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 183, 277)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 571)
[M::mem_pestat] mean and std.dev: (211.48, 109.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 718)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (674, 683, 2698)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6746)
[M::mem_pestat] mean and std.dev: (1674.71, 1487.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8770)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 313, 762)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1896)
[M::mem_pestat] mean and std.dev: (370.60, 348.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2463)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724988 sequences (100000067 bp) in 3.152 CPU sec, 3.344 real sec...
[M::process] read 724174 sequences (100000027 bp) in 2.340 CPU sec, 2.337 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 292703, 8, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (117, 280, 469)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1173)
[M::mem_pestat] mean and std.dev: (316.29, 247.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1525)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 187, 285)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 591)
[M::mem_pestat] mean and std.dev: (216.96, 113.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 744)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 249, 758)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2002)
[M::mem_pestat] mean and std.dev: (401.14, 352.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2624)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 728168 reads in 257.619 CPU sec, 8.197 real sec
[M::mem_process_seqs] Processed 725780 reads in 171.792 CPU sec, 5.481 real sec
sorting block 67, #reads = 1084351 mem = 536882824 peak = 840273920
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 292510, 12, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 507, 675)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1651)
[M::mem_pestat] mean and std.dev: (394.68, 256.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2139)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 188, 287)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 597)
[M::mem_pestat] mean and std.dev: (218.26, 114.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 752)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (473, 2559, 2655)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7019)
[M::mem_pestat] mean and std.dev: (1734.17, 1177.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9201)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 348, 1022)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2648)
[M::mem_pestat] mean and std.dev: (510.05, 454.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3461)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722922 sequences (100000187 bp) in 3.096 CPU sec, 3.245 real sec...
[M::process] read 722880 sequences (100000031 bp) in 2.084 CPU sec, 2.087 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (22, 291763, 25, 24)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 692, 2387)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6793)
[M::mem_pestat] mean and std.dev: (1475.59, 1790.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8996)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 189, 289)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 601)
[M::mem_pestat] mean and std.dev: (219.47, 115.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 757)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (44, 625, 1108)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3236)
[M::mem_pestat] mean and std.dev: (658.20, 613.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4300)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 258, 1155)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3131)
[M::mem_pestat] mean and std.dev: (460.95, 539.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4119)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 724988 reads in 244.753 CPU sec, 8.016 real sec
[M::mem_process_seqs] Processed 724174 reads in 159.396 CPU sec, 5.083 real sec
sorting block 68, #reads = 1084424 mem = 536877883 peak = 840273920
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 291783, 32, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 301, 849)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2171)
[M::mem_pestat] mean and std.dev: (399.50, 319.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2832)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 191, 293)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 611)
[M::mem_pestat] mean and std.dev: (221.84, 116.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 770)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (518, 1418, 2620)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6824)
[M::mem_pestat] mean and std.dev: (1687.88, 1339.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8926)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 533, 1247)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3321)
[M::mem_pestat] mean and std.dev: (777.36, 774.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4358)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724308 sequences (100000140 bp) in 2.921 CPU sec, 3.076 real sec...
[M::process] read 723584 sequences (100000250 bp) in 2.188 CPU sec, 2.189 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 291798, 23, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 254, 384)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 762)
[M::mem_pestat] mean and std.dev: (264.75, 133.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 951)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 192, 293)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 611)
[M::mem_pestat] mean and std.dev: (222.15, 116.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 770)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (456, 524, 789)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1455)
[M::mem_pestat] mean and std.dev: (553.24, 307.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1788)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 247, 411)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 943)
[M::mem_pestat] mean and std.dev: (286.10, 171.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1209)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 722922 reads in 234.208 CPU sec, 7.450 real sec
sorting block 69, #reads = 1085831 mem = 536882686 peak = 840273920
[M::mem_process_seqs] Processed 722880 reads in 151.430 CPU sec, 4.827 real sec
sorting block 70, #reads = 1088289 mem = 536879233 peak = 840273920
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 292268, 15, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 298, 1408)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3808)
[M::mem_pestat] mean and std.dev: (677.44, 628.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5008)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 190, 289)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 601)
[M::mem_pestat] mean and std.dev: (219.51, 115.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 757)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (472, 599, 1390)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3226)
[M::mem_pestat] mean and std.dev: (887.00, 742.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4144)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 242, 740)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1850)
[M::mem_pestat] mean and std.dev: (429.59, 349.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2405)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720908 sequences (100000258 bp) in 3.189 CPU sec, 3.333 real sec...
[M::process] read 720632 sequences (100000001 bp) in 2.301 CPU sec, 2.305 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 292253, 9, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 255, 794)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2054)
[M::mem_pestat] mean and std.dev: (427.23, 436.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2684)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 190, 290)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 604)
[M::mem_pestat] mean and std.dev: (220.25, 115.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 761)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 203, 518)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1254)
[M::mem_pestat] mean and std.dev: (373.67, 286.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1622)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 724308 reads in 242.572 CPU sec, 7.768 real sec
[M::mem_process_seqs] Processed 723584 reads in 156.185 CPU sec, 5.058 real sec
sorting block 71, #reads = 1089516 mem = 536879273 peak = 840273920
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 291609, 18, 23)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 470, 618)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1410)
[M::mem_pestat] mean and std.dev: (441.64, 241.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1806)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 195, 301)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 633)
[M::mem_pestat] mean and std.dev: (227.78, 121.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 799)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (561, 721, 1399)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3075)
[M::mem_pestat] mean and std.dev: (754.80, 530.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3913)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (245, 445, 941)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2333)
[M::mem_pestat] mean and std.dev: (472.95, 418.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3029)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720436 sequences (100000181 bp) in 3.198 CPU sec, 3.349 real sec...
[M::process] read 719844 sequences (100000247 bp) in 2.344 CPU sec, 2.352 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 291401, 13, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 445, 1620)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4476)
[M::mem_pestat] mean and std.dev: (941.65, 1060.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5904)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 196, 303)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 637)
[M::mem_pestat] mean and std.dev: (228.87, 123.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 804)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (283, 587, 2610)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7264)
[M::mem_pestat] mean and std.dev: (1221.62, 1611.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9591)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 252, 523)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1259)
[M::mem_pestat] mean and std.dev: (293.24, 183.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1627)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 720908 reads in 241.914 CPU sec, 7.806 real sec
[M::mem_process_seqs] Processed 720632 reads in 154.332 CPU sec, 4.915 real sec
sorting block 72, #reads = 1088203 mem = 536878668 peak = 840273920
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 291072, 16, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (245, 484, 772)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1826)
[M::mem_pestat] mean and std.dev: (428.53, 305.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2353)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 196, 301)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 633)
[M::mem_pestat] mean and std.dev: (227.65, 121.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 799)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (528, 1911, 3904)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10656)
[M::mem_pestat] mean and std.dev: (2450.50, 2278.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14032)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (267, 748, 1898)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5160)
[M::mem_pestat] mean and std.dev: (1568.47, 1789.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8728)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 719834 sequences (100000174 bp) in 3.108 CPU sec, 3.242 real sec...
[M::process] read 716826 sequences (100000118 bp) in 2.288 CPU sec, 2.290 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 290111, 12, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 218, 1414)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3932)
[M::mem_pestat] mean and std.dev: (452.11, 510.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5191)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 196, 300)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 628)
[M::mem_pestat] mean and std.dev: (227.40, 120.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 792)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (311, 666, 1442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3704)
[M::mem_pestat] mean and std.dev: (677.00, 470.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4835)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 292, 453)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 981)
[M::mem_pestat] mean and std.dev: (307.50, 176.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1245)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 720436 reads in 236.310 CPU sec, 7.548 real sec
sorting block 73, #reads = 1088008 mem = 536879559 peak = 840273920
[M::mem_process_seqs] Processed 719844 reads in 153.287 CPU sec, 4.870 real sec
sorting block 74, #reads = 1088177 mem = 536879181 peak = 840273920
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 290423, 11, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 357, 1229)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3289)
[M::mem_pestat] mean and std.dev: (662.05, 650.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4319)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::process] read 720078 sequences (100000077 bp) in 2.870 CPU sec, 3.031 real sec...
[M::mem_pestat] (25, 50, 75) percentile: (136, 196, 301)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 631)
[M::mem_pestat] mean and std.dev: (227.89, 121.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 796)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 235, 942)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2386)
[M::mem_pestat] mean and std.dev: (474.64, 401.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3108)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 264, 501)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1129)
[M::mem_pestat] mean and std.dev: (256.71, 113.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1443)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 719444 sequences (100000082 bp) in 1.922 CPU sec, 1.925 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 289456, 19, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (521, 669, 1923)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4727)
[M::mem_pestat] mean and std.dev: (987.31, 807.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6129)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (139, 202, 313)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 661)
[M::mem_pestat] mean and std.dev: (236.10, 128.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 835)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (233, 599, 698)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1628)
[M::mem_pestat] mean and std.dev: (459.00, 270.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2093)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 355, 770)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1890)
[M::mem_pestat] mean and std.dev: (475.31, 337.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2450)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 719834 reads in 234.672 CPU sec, 7.601 real sec
[M::mem_process_seqs] Processed 716826 reads in 149.850 CPU sec, 4.786 real sec
sorting block 75, #reads = 1086794 mem = 536880362 peak = 840273920
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 289893, 11, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 354, 565)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1233)
[M::mem_pestat] mean and std.dev: (329.71, 189.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1567)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 195, 298)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 622)
[M::mem_pestat] mean and std.dev: (225.92, 119.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 784)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (668, 995, 8109)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 22991)
[M::mem_pestat] mean and std.dev: (3010.36, 3281.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 30432)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (266, 471, 1944)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5300)
[M::mem_pestat] mean and std.dev: (961.46, 848.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6978)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 719800 sequences (100000141 bp) in 3.177 CPU sec, 3.304 real sec...
[M::process] read 720178 sequences (100000001 bp) in 2.305 CPU sec, 2.312 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 289910, 18, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (243, 292, 941)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2337)
[M::mem_pestat] mean and std.dev: (489.62, 379.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3035)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 197, 301)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 631)
[M::mem_pestat] mean and std.dev: (228.16, 121.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 796)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (115, 616, 3060)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8950)
[M::mem_pestat] mean and std.dev: (2058.72, 2782.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13189)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 301, 482)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1062)
[M::mem_pestat] mean and std.dev: (320.43, 199.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1352)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 720078 reads in 235.889 CPU sec, 7.502 real sec
[M::mem_process_seqs] Processed 719444 reads in 155.522 CPU sec, 5.260 real sec
sorting block 76, #reads = 1087583 mem = 536880893 peak = 840273920
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 290315, 9, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 425, 1168)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3138)
[M::mem_pestat] mean and std.dev: (510.03, 590.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4123)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 195, 299)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 625)
[M::mem_pestat] mean and std.dev: (226.20, 120.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 788)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 240, 413)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 921)
[M::mem_pestat] mean and std.dev: (224.07, 114.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1175)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 723760 sequences (100000099 bp) in 3.188 CPU sec, 3.323 real sec...
[M::process] read 722812 sequences (100000165 bp) in 2.220 CPU sec, 2.214 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 290308, 23, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (223, 465, 2376)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6682)
[M::mem_pestat] mean and std.dev: (1022.03, 1027.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8835)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 195, 298)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 622)
[M::mem_pestat] mean and std.dev: (225.92, 120.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 784)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (20, 382, 587)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1721)
[M::mem_pestat] mean and std.dev: (276.50, 273.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2288)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 399, 600)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1484)
[M::mem_pestat] mean and std.dev: (382.12, 303.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1926)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 719800 reads in 229.999 CPU sec, 7.622 real sec
sorting block 77, #reads = 1086491 mem = 536880341 peak = 840273920
[M::mem_process_seqs] Processed 720178 reads in 144.840 CPU sec, 4.706 real sec
sorting block 78, #reads = 1084980 mem = 536877510 peak = 840273920
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 291035, 14, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 438, 1060)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2814)
[M::mem_pestat] mean and std.dev: (659.41, 592.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3691)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 189, 289)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 601)
[M::mem_pestat] mean and std.dev: (219.72, 115.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 757)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (82, 1092, 1414)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4078)
[M::mem_pestat] mean and std.dev: (859.69, 1057.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5410)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 298, 479)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1025)
[M::mem_pestat] mean and std.dev: (333.19, 184.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1298)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722392 sequences (100000242 bp) in 2.975 CPU sec, 3.060 real sec...
[M::process] read 721896 sequences (100000075 bp) in 2.179 CPU sec, 2.180 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 291839, 26, 22)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 365, 4537)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13281)
[M::mem_pestat] mean and std.dev: (1662.44, 2166.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17653)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 191, 293)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 613)
[M::mem_pestat] mean and std.dev: (222.39, 118.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 773)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (393, 507, 983)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2163)
[M::mem_pestat] mean and std.dev: (567.13, 340.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2753)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 277, 558)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1330)
[M::mem_pestat] mean and std.dev: (302.00, 252.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1716)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 723760 reads in 224.070 CPU sec, 7.233 real sec
[M::mem_process_seqs] Processed 722812 reads in 134.952 CPU sec, 4.288 real sec
sorting block 79, #reads = 1082590 mem = 536879722 peak = 840273920
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20, 291688, 14, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (332, 559, 1171)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2849)
[M::mem_pestat] mean and std.dev: (652.50, 490.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3688)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 193, 295)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 617)
[M::mem_pestat] mean and std.dev: (224.10, 118.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 778)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 526, 985)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2627)
[M::mem_pestat] mean and std.dev: (384.09, 327.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3448)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 475, 634)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1488)
[M::mem_pestat] mean and std.dev: (447.44, 320.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1915)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 717504 sequences (100000288 bp) in 3.027 CPU sec, 3.157 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 291607, 25, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 325, 794)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1976)
[M::mem_pestat] mean and std.dev: (412.68, 367.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2567)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 194, 298)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 626)
[M::mem_pestat] mean and std.dev: (225.66, 120.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 790)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (85, 493, 1309)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3757)
[M::mem_pestat] mean and std.dev: (594.09, 882.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4981)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 281, 301)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 503)
[M::mem_pestat] mean and std.dev: (265.00, 103.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 678)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 721780 sequences (100000029 bp) in 2.170 CPU sec, 2.174 real sec...
[M::mem_process_seqs] Processed 722392 reads in 198.573 CPU sec, 6.418 real sec
[M::mem_process_seqs] Processed 721896 reads in 124.990 CPU sec, 3.991 real sec
sorting block 80, #reads = 1090413 mem = 536880119 peak = 840273920
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 290101, 10, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 296, 351)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 701)
[M::mem_pestat] mean and std.dev: (274.25, 125.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 876)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 203, 315)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 669)
[M::mem_pestat] mean and std.dev: (236.99, 128.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 846)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (71, 574, 1042)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2984)
[M::mem_pestat] mean and std.dev: (658.80, 601.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3955)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 356, 418)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 826)
[M::mem_pestat] mean and std.dev: (290.14, 123.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1030)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723500 sequences (100000188 bp) in 2.834 CPU sec, 2.954 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 291227, 14, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 468, 972)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2500)
[M::mem_pestat] mean and std.dev: (501.49, 345.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3264)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 194, 297)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 621)
[M::mem_pestat] mean and std.dev: (225.16, 119.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 783)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (328, 632, 857)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1915)
[M::mem_pestat] mean and std.dev: (577.08, 314.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2444)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 264, 537)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1287)
[M::mem_pestat] mean and std.dev: (318.93, 201.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1662)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723296 sequences (100000038 bp) in 2.270 CPU sec, 2.268 real sec...
[M::mem_process_seqs] Processed 717504 reads in 205.172 CPU sec, 6.556 real sec
sorting block 81, #reads = 1091778 mem = 536880485 peak = 840273920
[M::mem_process_seqs] Processed 721780 reads in 133.114 CPU sec, 4.309 real sec
sorting block 82, #reads = 1090331 mem = 536878122 peak = 840273920
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 292315, 22, 20)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 238, 473)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1097)
[M::mem_pestat] mean and std.dev: (288.31, 154.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1409)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 191, 291)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 607)
[M::mem_pestat] mean and std.dev: (220.86, 115.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 765)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (286, 785, 2087)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5689)
[M::mem_pestat] mean and std.dev: (949.45, 856.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7490)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (251, 286, 650)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1448)
[M::mem_pestat] mean and std.dev: (443.85, 314.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1847)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 721952 sequences (100000035 bp) in 2.869 CPU sec, 2.990 real sec...
[M::process] read 721926 sequences (100000121 bp) in 1.819 CPU sec, 1.820 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 291997, 14, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 318, 580)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1396)
[M::mem_pestat] mean and std.dev: (324.00, 189.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1804)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 190, 290)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 604)
[M::mem_pestat] mean and std.dev: (220.65, 115.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 761)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (79, 823, 1344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3874)
[M::mem_pestat] mean and std.dev: (757.38, 876.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5139)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 215, 384)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 856)
[M::mem_pestat] mean and std.dev: (270.82, 187.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1092)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 723500 reads in 222.541 CPU sec, 7.198 real sec
[M::mem_process_seqs] Processed 723296 reads in 142.114 CPU sec, 4.538 real sec
sorting block 83, #reads = 1091291 mem = 536877064 peak = 840273920
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 291880, 12, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 265, 444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 888)
[M::mem_pestat] mean and std.dev: (264.00, 145.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1110)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 193, 295)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 617)
[M::mem_pestat] mean and std.dev: (223.75, 118.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 778)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (242, 1135, 9989)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 29483)
[M::mem_pestat] mean and std.dev: (3110.83, 4053.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 39230)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 304, 534)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1154)
[M::mem_pestat] mean and std.dev: (294.31, 148.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1464)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 718464 sequences (100000039 bp) in 2.880 CPU sec, 3.017 real sec...
[M::process] read 721588 sequences (100000230 bp) in 2.128 CPU sec, 2.136 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 291613, 12, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (139, 197, 241)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 445)
[M::mem_pestat] mean and std.dev: (164.96, 47.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 547)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 193, 295)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 617)
[M::mem_pestat] mean and std.dev: (223.58, 118.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 778)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 975, 1394)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3816)
[M::mem_pestat] mean and std.dev: (730.27, 543.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5027)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (142, 213, 523)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1285)
[M::mem_pestat] mean and std.dev: (291.17, 272.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1666)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 721952 reads in 215.424 CPU sec, 6.862 real sec
[M::mem_process_seqs] Processed 721926 reads in 139.555 CPU sec, 4.539 real sec
sorting block 84, #reads = 1090726 mem = 536879446 peak = 840273920
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 290722, 22, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 279, 406)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 802)
[M::mem_pestat] mean and std.dev: (280.93, 141.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1000)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 200, 311)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 659)
[M::mem_pestat] mean and std.dev: (234.44, 126.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 833)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (601, 1647, 9018)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 25852)
[M::mem_pestat] mean and std.dev: (3838.41, 3960.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 34269)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 749, 994)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2570)
[M::mem_pestat] mean and std.dev: (530.25, 349.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3358)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 721260 sequences (100000176 bp) in 2.972 CPU sec, 3.089 real sec...
[M::process] read 720922 sequences (100000294 bp) in 2.060 CPU sec, 2.064 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 291358, 20, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 387, 996)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2594)
[M::mem_pestat] mean and std.dev: (507.08, 467.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3393)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 193, 296)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 618)
[M::mem_pestat] mean and std.dev: (224.19, 118.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 779)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (253, 546, 2708)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7618)
[M::mem_pestat] mean and std.dev: (1126.80, 1009.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10073)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 255, 699)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1671)
[M::mem_pestat] mean and std.dev: (356.25, 254.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2157)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 718464 reads in 214.941 CPU sec, 6.941 real sec
sorting block 85, #reads = 1091136 mem = 536880340 peak = 840273920
[M::mem_process_seqs] Processed 721588 reads in 134.600 CPU sec, 4.295 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 291336, 25, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 249, 347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 709)
[M::mem_pestat] mean and std.dev: (219.85, 80.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 890)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 194, 296)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 618)
[M::mem_pestat] mean and std.dev: (224.30, 118.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 779)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (737, 1420, 2074)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4748)
[M::mem_pestat] mean and std.dev: (1239.91, 735.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6085)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 446, 1102)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2934)
[M::mem_pestat] mean and std.dev: (529.50, 522.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3850)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 86, #reads = 1090070 mem = 536880396 peak = 840273920
[M::process] read 720904 sequences (100000285 bp) in 3.132 CPU sec, 3.280 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 291376, 23, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 332, 973)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2605)
[M::mem_pestat] mean and std.dev: (540.29, 492.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3421)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 195, 298)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 624)
[M::mem_pestat] mean and std.dev: (226.06, 119.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 787)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (235, 524, 1124)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2902)
[M::mem_pestat] mean and std.dev: (524.75, 462.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3791)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 192, 303)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 577)
[M::mem_pestat] mean and std.dev: (216.57, 74.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 714)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 721090 sequences (100000022 bp) in 2.099 CPU sec, 2.100 real sec...
[M::mem_process_seqs] Processed 721260 reads in 210.051 CPU sec, 6.717 real sec
[M::mem_process_seqs] Processed 720922 reads in 136.617 CPU sec, 4.360 real sec
sorting block 87, #reads = 1091098 mem = 536879092 peak = 840273920
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (17, 290897, 15, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (109, 354, 1016)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2830)
[M::mem_pestat] mean and std.dev: (451.20, 496.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3737)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 194, 298)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 624)
[M::mem_pestat] mean and std.dev: (225.89, 120.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 787)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (144, 307, 960)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2592)
[M::mem_pestat] mean and std.dev: (372.77, 357.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3408)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 351, 987)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2521)
[M::mem_pestat] mean and std.dev: (585.24, 617.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3288)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 721444 sequences (100000137 bp) in 3.003 CPU sec, 3.088 real sec...
[M::process] read 721148 sequences (100000204 bp) in 2.239 CPU sec, 2.235 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 290599, 30, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 256, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 739)
[M::mem_pestat] mean and std.dev: (238.90, 89.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 929)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 194, 295)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 615)
[M::mem_pestat] mean and std.dev: (224.19, 118.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 775)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (443, 646, 2790)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7484)
[M::mem_pestat] mean and std.dev: (1078.17, 1188.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9831)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (140, 372, 1575)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4445)
[M::mem_pestat] mean and std.dev: (778.64, 864.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5880)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 720904 reads in 205.559 CPU sec, 6.526 real sec
[M::mem_process_seqs] Processed 721090 reads in 131.858 CPU sec, 4.448 real sec
sorting block 88, #reads = 1089458 mem = 536878145 peak = 840273920
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 290688, 18, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 348, 993)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2611)
[M::mem_pestat] mean and std.dev: (611.12, 651.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3420)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 193, 296)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 618)
[M::mem_pestat] mean and std.dev: (224.28, 118.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 779)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (86, 917, 1201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3431)
[M::mem_pestat] mean and std.dev: (652.82, 590.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4546)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 303, 439)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 967)
[M::mem_pestat] mean and std.dev: (276.78, 138.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1231)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 721756 sequences (100000185 bp) in 3.090 CPU sec, 3.166 real sec...
[M::process] read 724776 sequences (100000141 bp) in 1.989 CPU sec, 1.988 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 290525, 14, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (144, 221, 1495)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4197)
[M::mem_pestat] mean and std.dev: (573.55, 701.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5548)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 193, 294)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 612)
[M::mem_pestat] mean and std.dev: (223.53, 118.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 771)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (403, 2013, 2295)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6079)
[M::mem_pestat] mean and std.dev: (1607.79, 1226.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7971)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 526, 625)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1509)
[M::mem_pestat] mean and std.dev: (461.00, 283.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1951)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 721444 reads in 217.077 CPU sec, 7.193 real sec
sorting block 89, #reads = 1088567 mem = 536876009 peak = 840273920
[M::mem_process_seqs] Processed 721148 reads in 142.881 CPU sec, 4.561 real sec
sorting block 90, #reads = 1086192 mem = 536879619 peak = 840273920
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 290655, 12, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 411, 778)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2012)
[M::mem_pestat] mean and std.dev: (407.12, 373.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2629)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 192, 291)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 605)
[M::mem_pestat] mean and std.dev: (221.40, 115.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 762)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (265, 948, 1383)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3619)
[M::mem_pestat] mean and std.dev: (671.40, 453.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4737)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 414, 1920)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5318)
[M::mem_pestat] mean and std.dev: (888.64, 870.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7017)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 727096 sequences (100000118 bp) in 2.964 CPU sec, 3.051 real sec...
[M::process] read 726388 sequences (100000028 bp) in 2.080 CPU sec, 2.082 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 291448, 13, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 227, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 752)
[M::mem_pestat] mean and std.dev: (250.97, 126.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 946)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 188, 284)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 588)
[M::mem_pestat] mean and std.dev: (216.33, 112.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 740)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (295, 944, 2093)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5689)
[M::mem_pestat] mean and std.dev: (1187.85, 1104.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7487)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 358, 901)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2291)
[M::mem_pestat] mean and std.dev: (474.15, 399.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2986)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 721756 reads in 237.122 CPU sec, 7.556 real sec
[M::mem_process_seqs] Processed 724776 reads in 166.221 CPU sec, 5.313 real sec
sorting block 91, #reads = 1082841 mem = 536880890 peak = 840273920
[M::process] read 726312 sequences (100000145 bp) in 3.022 CPU sec, 3.117 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 292958, 17, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 363, 1697)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4699)
[M::mem_pestat] mean and std.dev: (551.38, 838.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6200)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 185, 283)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 587)
[M::mem_pestat] mean and std.dev: (215.85, 113.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 739)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (61, 244, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 883)
[M::mem_pestat] mean and std.dev: (225.69, 182.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1157)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (253, 291, 1493)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3973)
[M::mem_pestat] mean and std.dev: (595.96, 726.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5213)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723046 sequences (100000104 bp) in 2.205 CPU sec, 2.215 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 293331, 15, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 274, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 676)
[M::mem_pestat] mean and std.dev: (250.14, 108.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 831)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 186, 283)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 587)
[M::mem_pestat] mean and std.dev: (215.78, 112.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 739)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (102, 1077, 1677)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4827)
[M::mem_pestat] mean and std.dev: (1064.73, 1170.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6402)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 281, 505)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1109)
[M::mem_pestat] mean and std.dev: (338.90, 189.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1411)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 293017, 19, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (136, 203, 318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 682)
[M::mem_pestat] mean and std.dev: (202.62, 103.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 864)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 186, 283)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 587)
[M::mem_pestat] mean and std.dev: (216.02, 113.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 739)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (733, 741, 993)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (213, 1513)
[M::mem_pestat] mean and std.dev: (729.47, 290.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1891)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 274, 1126)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3022)
[M::mem_pestat] mean and std.dev: (586.92, 644.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3970)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 727096 reads in 358.165 CPU sec, 11.497 real sec
[M::mem_process_seqs] Processed 726312 reads in 266.596 CPU sec, 8.563 real sec
sorting block 92, #reads = 1081752 mem = 536879013 peak = 840273920
[M::mem_process_seqs] Processed 726388 reads in 297.183 CPU sec, 9.594 real sec
[M::process] read 726362 sequences (100000134 bp) in 3.066 CPU sec, 3.256 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 292600, 16, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 250, 556)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1334)
[M::mem_pestat] mean and std.dev: (302.67, 238.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1723)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 192, 298)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 626)
[M::mem_pestat] mean and std.dev: (225.61, 121.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 790)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (50, 950, 1292)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3776)
[M::mem_pestat] mean and std.dev: (920.94, 1001.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5018)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 296, 1520)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4160)
[M::mem_pestat] mean and std.dev: (845.33, 994.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5480)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 93, #reads = 1085826 mem = 536885091 peak = 840273920
[M::process] read 726976 sequences (100000133 bp) in 3.029 CPU sec, 3.250 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 293280, 27, 21)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (146, 482, 1393)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3887)
[M::mem_pestat] mean and std.dev: (395.35, 360.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5134)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 186, 283)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 587)
[M::mem_pestat] mean and std.dev: (216.04, 113.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 739)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (105, 649, 1934)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5592)
[M::mem_pestat] mean and std.dev: (1199.00, 1462.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7421)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 388, 1017)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2647)
[M::mem_pestat] mean and std.dev: (573.75, 414.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3462)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 723046 reads in 247.622 CPU sec, 8.000 real sec
[M::mem_process_seqs] Processed 726362 reads in 163.604 CPU sec, 5.190 real sec
[M::process] read 725736 sequences (100000271 bp) in 2.607 CPU sec, 2.739 real sec...
sorting block 94, #reads = 1085291 mem = 536879577 peak = 840273920
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 293250, 12, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (141, 211, 418)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 972)
[M::mem_pestat] mean and std.dev: (232.88, 147.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1249)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 185, 280)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 578)
[M::mem_pestat] mean and std.dev: (213.44, 110.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 727)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (62, 1277, 1658)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4850)
[M::mem_pestat] mean and std.dev: (971.42, 764.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6446)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 257, 514)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1150)
[M::mem_pestat] mean and std.dev: (295.37, 168.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1468)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724354 sequences (100000102 bp) in 2.630 CPU sec, 2.796 real sec...
[M::process] read 720268 sequences (100000077 bp) in 2.424 CPU sec, 2.434 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 292717, 14, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 361, 839)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2191)
[M::mem_pestat] mean and std.dev: (408.03, 367.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2867)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 187, 283)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 587)
[M::mem_pestat] mean and std.dev: (215.78, 111.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 739)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (842, 1424, 4059)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10493)
[M::mem_pestat] mean and std.dev: (2041.21, 1864.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13710)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 264, 459)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1037)
[M::mem_pestat] mean and std.dev: (281.16, 148.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1326)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 726976 reads in 245.317 CPU sec, 7.848 real sec
sorting block 95, #reads = 1090747 mem = 536877912 peak = 840273920
[M::mem_process_seqs] Processed 725736 reads in 160.920 CPU sec, 5.125 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 291790, 23, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (233, 319, 736)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1742)
[M::mem_pestat] mean and std.dev: (375.68, 245.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2245)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 188, 286)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 592)
[M::mem_pestat] mean and std.dev: (217.85, 112.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 745)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1025, 2135, 2575)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5675)
[M::mem_pestat] mean and std.dev: (1797.05, 1009.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7225)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 334, 615)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1467)
[M::mem_pestat] mean and std.dev: (403.81, 321.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1893)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 96, #reads = 1088815 mem = 536879060 peak = 840273920
[M::process] read 723248 sequences (100000150 bp) in 3.175 CPU sec, 3.375 real sec...
[M::process] read 722436 sequences (100000049 bp) in 2.342 CPU sec, 2.346 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 290509, 26, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 223, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 674)
[M::mem_pestat] mean and std.dev: (223.44, 77.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 828)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 196, 301)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 631)
[M::mem_pestat] mean and std.dev: (227.95, 120.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 796)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 786, 1108)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2988)
[M::mem_pestat] mean and std.dev: (762.46, 582.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3928)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 279, 525)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1191)
[M::mem_pestat] mean and std.dev: (252.83, 112.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1524)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 724354 reads in 233.858 CPU sec, 7.463 real sec
[M::mem_process_seqs] Processed 720268 reads in 152.390 CPU sec, 4.834 real sec
sorting block 97, #reads = 1089742 mem = 536881538 peak = 840273920
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23, 291661, 15, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 283, 657)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1591)
[M::mem_pestat] mean and std.dev: (440.45, 392.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2058)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 191, 291)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 607)
[M::mem_pestat] mean and std.dev: (221.21, 116.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 765)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (500, 956, 2442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6326)
[M::mem_pestat] mean and std.dev: (1198.73, 903.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8268)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 227, 893)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2247)
[M::mem_pestat] mean and std.dev: (388.19, 347.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2924)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722132 sequences (100000116 bp) in 3.334 CPU sec, 3.477 real sec...
[M::process] read 722014 sequences (100000110 bp) in 1.864 CPU sec, 1.867 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (16, 291738, 19, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 229, 371)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 773)
[M::mem_pestat] mean and std.dev: (251.67, 116.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 974)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 192, 294)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 614)
[M::mem_pestat] mean and std.dev: (223.25, 117.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 774)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1112, 1219, 1817)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3227)
[M::mem_pestat] mean and std.dev: (1156.41, 596.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3932)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 297, 1324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3576)
[M::mem_pestat] mean and std.dev: (779.81, 847.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4702)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 723248 reads in 230.213 CPU sec, 7.330 real sec
[M::mem_process_seqs] Processed 722436 reads in 150.513 CPU sec, 4.797 real sec
sorting block 98, #reads = 1087879 mem = 536878644 peak = 840273920
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 291730, 18, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 283, 958)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2512)
[M::mem_pestat] mean and std.dev: (489.69, 520.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3289)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 193, 294)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 614)
[M::mem_pestat] mean and std.dev: (223.61, 117.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 774)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (394, 485, 3240)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8932)
[M::mem_pestat] mean and std.dev: (1295.89, 1472.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11778)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 533, 1468)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4066)
[M::mem_pestat] mean and std.dev: (955.39, 935.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5365)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 721522 sequences (100000006 bp) in 2.955 CPU sec, 3.117 real sec...
[M::process] read 720928 sequences (100000082 bp) in 2.131 CPU sec, 2.135 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 291107, 19, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 689, 689)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1709)
[M::mem_pestat] mean and std.dev: (572.27, 422.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2263)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 193, 295)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 617)
[M::mem_pestat] mean and std.dev: (223.65, 117.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 778)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (557, 773, 1702)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3992)
[M::mem_pestat] mean and std.dev: (959.61, 705.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5137)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (273, 447, 766)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1752)
[M::mem_pestat] mean and std.dev: (427.89, 235.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2245)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 722132 reads in 226.604 CPU sec, 7.224 real sec
sorting block 99, #reads = 1088597 mem = 536879229 peak = 840273920
[M::mem_process_seqs] Processed 722014 reads in 149.007 CPU sec, 4.731 real sec
sorting block 100, #reads = 1091098 mem = 536886464 peak = 840273920
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 291128, 17, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (104, 189, 492)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1268)
[M::mem_pestat] mean and std.dev: (229.19, 213.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1656)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 194, 295)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 615)
[M::mem_pestat] mean and std.dev: (223.84, 117.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 775)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (383, 741, 1417)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3485)
[M::mem_pestat] mean and std.dev: (928.71, 820.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4519)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 443, 1303)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3513)
[M::mem_pestat] mean and std.dev: (724.45, 699.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4618)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 721380 sequences (100000143 bp) in 2.832 CPU sec, 2.998 real sec...
[M::process] read 720474 sequences (100000211 bp) in 2.303 CPU sec, 2.306 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 290451, 19, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (144, 196, 834)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2214)
[M::mem_pestat] mean and std.dev: (439.24, 469.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2904)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 194, 295)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 615)
[M::mem_pestat] mean and std.dev: (223.97, 117.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 775)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (549, 1429, 3188)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8466)
[M::mem_pestat] mean and std.dev: (2016.74, 1751.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11105)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (339, 718, 1178)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2856)
[M::mem_pestat] mean and std.dev: (647.28, 434.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3695)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 721522 reads in 230.864 CPU sec, 7.358 real sec
[M::mem_process_seqs] Processed 720928 reads in 151.632 CPU sec, 4.826 real sec
sorting block 101, #reads = 1088998 mem = 536878658 peak = 840273920
[M::process] read 591976 sequences (81921555 bp) in 2.327 CPU sec, 2.419 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 290866, 19, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 272, 615)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1517)
[M::mem_pestat] mean and std.dev: (360.15, 325.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1968)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 193, 294)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 612)
[M::mem_pestat] mean and std.dev: (223.40, 117.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 771)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 639, 1171)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3103)
[M::mem_pestat] mean and std.dev: (775.95, 650.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4069)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 268, 497)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1053)
[M::mem_pestat] mean and std.dev: (292.77, 155.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1331)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 238803, 18, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (146, 267, 583)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1457)
[M::mem_pestat] mean and std.dev: (339.96, 278.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1894)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 191, 290)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 604)
[M::mem_pestat] mean and std.dev: (220.19, 115.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 761)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (55, 454, 1385)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4045)
[M::mem_pestat] mean and std.dev: (767.61, 797.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5375)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 444, 592)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1352)
[M::mem_pestat] mean and std.dev: (431.77, 318.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1732)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 290901, 11, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (258, 350, 781)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1827)
[M::mem_pestat] mean and std.dev: (523.32, 400.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2350)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 194, 297)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 621)
[M::mem_pestat] mean and std.dev: (225.45, 119.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 783)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (105, 301, 635)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1695)
[M::mem_pestat] mean and std.dev: (263.11, 193.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2225)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 259, 691)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1729)
[M::mem_pestat] mean and std.dev: (427.39, 434.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2248)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 721380 reads in 307.819 CPU sec, 9.934 real sec
[M::mem_process_seqs] Processed 591976 reads in 224.685 CPU sec, 7.263 real sec
sorting block 102, #reads = 1088419 mem = 536879243 peak = 840273920
[M::mem_process_seqs] Processed 720474 reads in 249.520 CPU sec, 8.093 real sec
sorting block 103, #reads = 1087753 mem = 536882477 peak = 840273920
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000a06d1
  features: 1f8bfbff fffab20b
  extended: f1bf27eb 1b407f7e
  amd bits: 2c100800 00000121
     brand: Intel(R) Xeon(R) 6975P-C
threads: 31
algo: bwa-mem
license: sentieon:klib=31
reads: 112873218
overall: 70174064640 mem 21225.726 user 951.427 sys 751.965 real
[main] Version: 0.7.17-r1188
[main] CMD: /opt/conda/share/sentieon-202308.03-3/libexec/bwa mem -K 100000000 -Y -R @RG\tID:A23MHWWLT4.1136_8DV-T1-TDNA-1_A23MHWWLT4_1.L008\tPU:L008\tSM:1136_8DV-T1-TDNA-1_A23MHWWLT4_1\tLB:1136_8DV-T1-TDNA-1_A23MHWWLT4_1\tDS:s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta\tPL:ILLUMINA -t 31 ./BWAIndex/Homo_sapiens_assembly38.fasta.64 1136_8DV-T1-TDNA-1_A23MHWWLT4_1_R1.fastq.gz 1136_8DV-T1-TDNA-1_A23MHWWLT4_1_R2.fastq.gz
[main] Real time: 751.997 sec; CPU: 22177.157 sec
sorting block 104, #reads = 425769 mem = 210119750 peak = 840273920
uniq header count 1
merging 105 blocks
sw version: sentieon-genomics-202308.03
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000a06d1
  features: 1f8bfbff fffab20b
  extended: f1bf27eb 1b407f7e
  amd bits: 2c100800 00000121
     brand: Intel(R) Xeon(R) 6975P-C
threads: 31 max 384
algo: util-sort
license: sentieon:util=1
output file size: 6190194445
output reads: 113705017
bam_mem_sort: 105 calls 85.972 user 1.785 sys 87.919 real
bam_write: 105 calls 48.536 user 4.102 sys 58.415 real
execute: 1 calls 46.144 user 3.869 sys 807.850 real
merge_files: 1 calls 46.132 user 3.821 sys 55.324 real
parse_chunk: 1671 calls 81.217 user 22.010 sys 105.698 real
read_chunk: 4528 calls 58.366 user 32.981 sys 648.253 real
sort_block: 1 calls 39.597 user 31.589 sys 621.622 real
write_chunk: 2855 calls 45.532 user 3.392 sys 53.916 real
overall: 2962411520 mem 1871.592 user 96.562 sys 807.867 real
ls: cannot access '*.cram': No such file or directory