File Info

Filename
.command.err
Full Path
s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/41/abfdfa22a1b1b18e3e0e0dcb0af07e/.command.err
Size
429.1 KB
Attempt
This software is licensed to bgold@natera.com by Sentieon Inc.
cmdline: /opt/conda/share/sentieon-202308.03-3/libexec/util sort -r Homo_sapiens_assembly38.fasta -t 31 -o 1029_HTI-T1-TDNA-1_A23MHWWLT4_1.bam --sam2bam -
This software is licensed to bgold@natera.com by Sentieon Inc.
version: sentieon-genomics-202308.03
[M::bwa_idx_load_from_disk] read 3171 ALT contigs
[M::main_mem] bwa index loaded in 1811.733 CPU sec, 65.007 real sec
[M::process] read 704916 sequences (100000265 bp) in 1.649 CPU sec, 1.652 real sec...
[M::process] read 701794 sequences (100000149 bp) in 1.889 CPU sec, 1.890 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 283844, 23, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 323, 547)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1237)
[M::mem_pestat] mean and std.dev: (329.10, 206.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1582)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 214, 307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 623)
[M::mem_pestat] mean and std.dev: (237.07, 114.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 781)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (344, 1008, 2149)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5759)
[M::mem_pestat] mean and std.dev: (1030.26, 808.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7564)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (241, 328, 717)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1669)
[M::mem_pestat] mean and std.dev: (485.70, 371.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2145)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701180 sequences (100000204 bp) in 1.806 CPU sec, 1.844 real sec...
[M::process] read 701080 sequences (100000263 bp) in 1.747 CPU sec, 1.832 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 283400, 30, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 281, 1114)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3046)
[M::mem_pestat] mean and std.dev: (443.65, 500.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4012)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 223, 320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 654)
[M::mem_pestat] mean and std.dev: (246.20, 119.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 821)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (415, 661, 1675)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4195)
[M::mem_pestat] mean and std.dev: (1107.19, 1292.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6277)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (236, 363, 997)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2519)
[M::mem_pestat] mean and std.dev: (552.50, 517.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3280)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704916 reads in 228.295 CPU sec, 7.399 real sec
[M::mem_process_seqs] Processed 701794 reads in 146.136 CPU sec, 4.867 real sec
sorting block 0, #reads = 1074663 mem = 536879914 peak = 593682432
[M::process] read 700490 sequences (100000247 bp) in 2.240 CPU sec, 2.453 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 282385, 23, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (299, 352, 1091)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2675)
[M::mem_pestat] mean and std.dev: (543.00, 476.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3467)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 224, 323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 661)
[M::mem_pestat] mean and std.dev: (248.00, 120.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 830)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (251, 738, 2175)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6023)
[M::mem_pestat] mean and std.dev: (1209.61, 1378.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7947)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 395, 759)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1833)
[M::mem_pestat] mean and std.dev: (494.21, 377.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2370)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699872 sequences (100000148 bp) in 1.913 CPU sec, 1.917 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 282731, 26, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 276, 561)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1383)
[M::mem_pestat] mean and std.dev: (358.55, 310.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1794)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 225, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 667)
[M::mem_pestat] mean and std.dev: (249.35, 121.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 838)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 621, 1042)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2802)
[M::mem_pestat] mean and std.dev: (541.57, 473.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3682)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 265, 888)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2274)
[M::mem_pestat] mean and std.dev: (473.02, 421.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2967)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 282273, 26, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (246, 780, 1526)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4086)
[M::mem_pestat] mean and std.dev: (885.66, 794.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5366)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 226, 327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 671)
[M::mem_pestat] mean and std.dev: (250.68, 121.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 843)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 969, 2023)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5765)
[M::mem_pestat] mean and std.dev: (1429.12, 1701.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8236)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (232, 391, 991)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2509)
[M::mem_pestat] mean and std.dev: (601.62, 534.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3268)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701180 reads in 293.648 CPU sec, 9.625 real sec
[M::mem_process_seqs] Processed 701080 reads in 231.188 CPU sec, 7.639 real sec
sorting block 1, #reads = 1074442 mem = 536878949 peak = 757260288
[M::mem_process_seqs] Processed 700490 reads in 260.037 CPU sec, 8.584 real sec
[M::process] read 699528 sequences (100000143 bp) in 2.487 CPU sec, 2.719 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 282262, 29, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (270, 615, 1019)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2517)
[M::mem_pestat] mean and std.dev: (668.27, 494.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3266)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 228, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 678)
[M::mem_pestat] mean and std.dev: (252.49, 122.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 852)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (259, 842, 2310)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6412)
[M::mem_pestat] mean and std.dev: (1298.31, 1205.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8463)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 482, 1046)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2774)
[M::mem_pestat] mean and std.dev: (558.14, 437.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3638)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 2, #reads = 1073691 mem = 536878623 peak = 903491584
[M::process] read 699100 sequences (100000166 bp) in 2.576 CPU sec, 2.663 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 282423, 30, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (238, 563, 1050)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2674)
[M::mem_pestat] mean and std.dev: (680.56, 516.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3486)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 230, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 679)
[M::mem_pestat] mean and std.dev: (253.88, 123.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 853)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (229, 777, 1642)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4468)
[M::mem_pestat] mean and std.dev: (1026.96, 937.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5881)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 339, 687)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1659)
[M::mem_pestat] mean and std.dev: (425.40, 295.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2145)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698628 sequences (100000261 bp) in 1.871 CPU sec, 1.918 real sec...
[M::mem_process_seqs] Processed 699872 reads in 215.090 CPU sec, 6.927 real sec
[M::mem_process_seqs] Processed 699528 reads in 150.309 CPU sec, 4.821 real sec
sorting block 3, #reads = 1072365 mem = 536882829 peak = 903491584
[M::process] read 698462 sequences (100000022 bp) in 2.421 CPU sec, 2.576 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 282314, 20, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 328, 838)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2126)
[M::mem_pestat] mean and std.dev: (493.44, 518.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2770)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 230, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 682)
[M::mem_pestat] mean and std.dev: (254.46, 123.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 857)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (557, 1036, 1834)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4388)
[M::mem_pestat] mean and std.dev: (1127.58, 1010.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5665)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 352, 720)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1742)
[M::mem_pestat] mean and std.dev: (422.97, 346.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2253)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698212 sequences (100000077 bp) in 2.056 CPU sec, 2.064 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 282604, 33, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 478, 1105)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2911)
[M::mem_pestat] mean and std.dev: (672.13, 566.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3814)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 232, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 689)
[M::mem_pestat] mean and std.dev: (256.23, 124.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 866)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (360, 904, 2028)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5364)
[M::mem_pestat] mean and std.dev: (1247.06, 1249.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7032)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 372, 1305)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3519)
[M::mem_pestat] mean and std.dev: (732.38, 806.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4626)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 283024, 33, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 304, 877)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2233)
[M::mem_pestat] mean and std.dev: (454.77, 411.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2911)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 232, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 689)
[M::mem_pestat] mean and std.dev: (256.41, 124.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 866)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (83, 355, 938)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2648)
[M::mem_pestat] mean and std.dev: (482.19, 481.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3503)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 343, 491)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1095)
[M::mem_pestat] mean and std.dev: (303.11, 181.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1397)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699100 reads in 294.452 CPU sec, 9.585 real sec
sorting block 4, #reads = 1073305 mem = 536880275 peak = 903491584
[M::mem_process_seqs] Processed 698628 reads in 231.859 CPU sec, 7.508 real sec
[M::mem_process_seqs] Processed 698462 reads in 258.629 CPU sec, 8.425 real sec
[M::process] read 697838 sequences (100000116 bp) in 2.470 CPU sec, 2.776 real sec...
sorting block 5, #reads = 1074648 mem = 536878485 peak = 920133632
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 281969, 37, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 559, 681)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1675)
[M::mem_pestat] mean and std.dev: (400.42, 242.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2172)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 232, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 683)
[M::mem_pestat] mean and std.dev: (255.96, 124.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 858)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 651, 1108)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2908)
[M::mem_pestat] mean and std.dev: (703.12, 656.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3808)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 229, 977)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2585)
[M::mem_pestat] mean and std.dev: (496.32, 602.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3389)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698062 sequences (100000126 bp) in 2.541 CPU sec, 2.895 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 281791, 20, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (142, 247, 642)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1642)
[M::mem_pestat] mean and std.dev: (338.21, 281.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2142)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 234, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 694)
[M::mem_pestat] mean and std.dev: (258.92, 126.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 872)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (429, 576, 1053)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2301)
[M::mem_pestat] mean and std.dev: (722.60, 512.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2925)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (310, 477, 1189)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2947)
[M::mem_pestat] mean and std.dev: (751.98, 733.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3826)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698212 reads in 205.386 CPU sec, 6.726 real sec
[M::process] read 697384 sequences (100000065 bp) in 2.239 CPU sec, 2.300 real sec...
[M::mem_process_seqs] Processed 697838 reads in 143.109 CPU sec, 4.614 real sec
sorting block 6, #reads = 1073167 mem = 536882027 peak = 920133632
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 282404, 25, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 241, 741)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1865)
[M::mem_pestat] mean and std.dev: (348.98, 324.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2427)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 234, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 699)
[M::mem_pestat] mean and std.dev: (259.01, 126.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 879)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (455, 717, 2304)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6002)
[M::mem_pestat] mean and std.dev: (833.68, 786.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7851)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 468, 861)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2169)
[M::mem_pestat] mean and std.dev: (545.49, 498.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2823)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696632 sequences (100000226 bp) in 2.423 CPU sec, 2.754 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 282399, 26, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (258, 646, 1188)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3048)
[M::mem_pestat] mean and std.dev: (757.68, 506.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3978)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 235, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 700)
[M::mem_pestat] mean and std.dev: (259.86, 126.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 880)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (819, 1402, 1677)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3393)
[M::mem_pestat] mean and std.dev: (1028.55, 494.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4251)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 295, 1024)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2672)
[M::mem_pestat] mean and std.dev: (620.98, 632.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3496)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697104 sequences (100000098 bp) in 1.953 CPU sec, 1.967 real sec...
[M::mem_process_seqs] Processed 698062 reads in 199.094 CPU sec, 6.543 real sec
sorting block 7, #reads = 1072196 mem = 536880730 peak = 920133632
[M::mem_process_seqs] Processed 697384 reads in 144.551 CPU sec, 4.638 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 281746, 39, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 308, 696)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1684)
[M::mem_pestat] mean and std.dev: (442.32, 352.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2178)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 237, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 701)
[M::mem_pestat] mean and std.dev: (261.15, 127.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 881)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 336, 1172)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3178)
[M::mem_pestat] mean and std.dev: (713.61, 739.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4181)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 293, 1134)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2980)
[M::mem_pestat] mean and std.dev: (559.14, 574.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3903)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 8, #reads = 1073680 mem = 536879501 peak = 920592384
[M::process] read 697150 sequences (100000235 bp) in 2.484 CPU sec, 2.990 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 282234, 35, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 443, 888)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2314)
[M::mem_pestat] mean and std.dev: (459.47, 410.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3027)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 235, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 697)
[M::mem_pestat] mean and std.dev: (259.70, 126.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 876)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 490, 1606)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4432)
[M::mem_pestat] mean and std.dev: (853.88, 933.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5845)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 313, 772)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1924)
[M::mem_pestat] mean and std.dev: (431.48, 327.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2500)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697058 sequences (100000234 bp) in 2.112 CPU sec, 2.147 real sec...
[M::mem_process_seqs] Processed 696632 reads in 195.099 CPU sec, 6.306 real sec
[M::mem_process_seqs] Processed 697104 reads in 140.908 CPU sec, 4.684 real sec
sorting block 9, #reads = 1073343 mem = 536884468 peak = 920592384
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 282271, 21, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 345, 760)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1918)
[M::mem_pestat] mean and std.dev: (446.53, 450.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2497)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 235, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 700)
[M::mem_pestat] mean and std.dev: (260.11, 126.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 880)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 521, 971)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2539)
[M::mem_pestat] mean and std.dev: (577.38, 430.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3323)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (354, 599, 1608)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4116)
[M::mem_pestat] mean and std.dev: (860.17, 761.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5370)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696406 sequences (100000269 bp) in 2.666 CPU sec, 2.951 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 281864, 20, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 305, 923)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2335)
[M::mem_pestat] mean and std.dev: (604.21, 518.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3041)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 236, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 698)
[M::mem_pestat] mean and std.dev: (260.11, 126.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 877)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (445, 792, 2647)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7051)
[M::mem_pestat] mean and std.dev: (1249.70, 1151.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9253)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (280, 395, 666)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1438)
[M::mem_pestat] mean and std.dev: (427.04, 254.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1824)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696092 sequences (100000224 bp) in 2.154 CPU sec, 2.159 real sec...
[M::mem_process_seqs] Processed 697150 reads in 201.474 CPU sec, 6.746 real sec
[M::mem_process_seqs] Processed 697058 reads in 142.434 CPU sec, 4.690 real sec
sorting block 10, #reads = 1072187 mem = 536878343 peak = 920592384
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 280855, 20, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (243, 601, 922)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2280)
[M::mem_pestat] mean and std.dev: (585.38, 413.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2959)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 236, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 698)
[M::mem_pestat] mean and std.dev: (260.55, 126.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 877)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (236, 617, 1369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3635)
[M::mem_pestat] mean and std.dev: (763.89, 702.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4768)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 331, 926)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2334)
[M::mem_pestat] mean and std.dev: (534.47, 489.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3038)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695906 sequences (100000109 bp) in 2.606 CPU sec, 2.983 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 281517, 23, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (143, 263, 1100)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3014)
[M::mem_pestat] mean and std.dev: (601.10, 677.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3971)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 237, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 693)
[M::mem_pestat] mean and std.dev: (259.93, 124.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 870)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (105, 621, 975)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2715)
[M::mem_pestat] mean and std.dev: (629.45, 508.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3585)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (254, 545, 2061)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5675)
[M::mem_pestat] mean and std.dev: (901.03, 813.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7482)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695884 sequences (100000161 bp) in 2.184 CPU sec, 2.211 real sec...
[M::mem_process_seqs] Processed 696406 reads in 201.376 CPU sec, 6.569 real sec
sorting block 11, #reads = 1072139 mem = 536878999 peak = 920592384
[M::mem_process_seqs] Processed 696092 reads in 140.776 CPU sec, 4.601 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 281025, 29, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 408, 809)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2061)
[M::mem_pestat] mean and std.dev: (533.35, 430.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2687)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 238, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 696)
[M::mem_pestat] mean and std.dev: (260.80, 125.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 874)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (384, 922, 1322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3198)
[M::mem_pestat] mean and std.dev: (850.04, 554.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4136)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (311, 593, 1067)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2579)
[M::mem_pestat] mean and std.dev: (763.56, 604.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3335)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 12, #reads = 1071971 mem = 536878683 peak = 927707136
[M::process] read 696082 sequences (100000151 bp) in 2.547 CPU sec, 3.129 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 281175, 32, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 251, 680)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1708)
[M::mem_pestat] mean and std.dev: (413.45, 399.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2222)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 237, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 693)
[M::mem_pestat] mean and std.dev: (259.92, 124.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 870)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (97, 816, 2556)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7474)
[M::mem_pestat] mean and std.dev: (1078.14, 1429.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9933)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 766, 1821)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5107)
[M::mem_pestat] mean and std.dev: (908.48, 893.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6750)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696378 sequences (100000213 bp) in 2.169 CPU sec, 2.173 real sec...
[M::mem_process_seqs] Processed 695906 reads in 201.618 CPU sec, 6.644 real sec
[M::mem_process_seqs] Processed 695884 reads in 142.193 CPU sec, 4.618 real sec
sorting block 13, #reads = 1070567 mem = 536881057 peak = 927707136
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 281185, 20, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 266, 522)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1214)
[M::mem_pestat] mean and std.dev: (323.25, 223.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1560)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 236, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 684)
[M::mem_pestat] mean and std.dev: (258.21, 122.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 858)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (294, 633, 1312)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3348)
[M::mem_pestat] mean and std.dev: (587.06, 435.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4366)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 268, 924)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2344)
[M::mem_pestat] mean and std.dev: (454.11, 445.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3054)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696402 sequences (100000039 bp) in 2.655 CPU sec, 2.989 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 281030, 13, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 332, 587)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1317)
[M::mem_pestat] mean and std.dev: (449.12, 315.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1712)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 236, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 686)
[M::mem_pestat] mean and std.dev: (257.96, 123.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 861)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (560, 928, 1989)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4847)
[M::mem_pestat] mean and std.dev: (1167.31, 799.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6276)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (241, 449, 1285)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3373)
[M::mem_pestat] mean and std.dev: (774.12, 749.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4417)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696264 sequences (100000037 bp) in 2.153 CPU sec, 2.162 real sec...
[M::mem_process_seqs] Processed 696082 reads in 200.545 CPU sec, 6.505 real sec
[M::mem_process_seqs] Processed 696378 reads in 141.873 CPU sec, 4.624 real sec
sorting block 14, #reads = 1071890 mem = 536880484 peak = 927707136
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 280988, 34, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 282, 520)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1226)
[M::mem_pestat] mean and std.dev: (283.70, 174.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1579)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 236, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 683)
[M::mem_pestat] mean and std.dev: (257.50, 122.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 857)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (105, 511, 1031)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2883)
[M::mem_pestat] mean and std.dev: (657.82, 628.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3809)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 284, 683)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1717)
[M::mem_pestat] mean and std.dev: (434.06, 395.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2234)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696306 sequences (100000160 bp) in 2.707 CPU sec, 2.938 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 281135, 36, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 272, 643)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1625)
[M::mem_pestat] mean and std.dev: (345.71, 281.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2116)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 236, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 684)
[M::mem_pestat] mean and std.dev: (257.97, 122.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 858)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (570, 635, 1653)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3819)
[M::mem_pestat] mean and std.dev: (818.81, 676.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4902)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 270, 714)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1814)
[M::mem_pestat] mean and std.dev: (379.43, 333.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2364)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696402 sequences (100000077 bp) in 2.525 CPU sec, 2.555 real sec...
[M::mem_process_seqs] Processed 696402 reads in 205.270 CPU sec, 6.575 real sec
sorting block 15, #reads = 1070206 mem = 536877410 peak = 939819008
[M::mem_process_seqs] Processed 696264 reads in 145.226 CPU sec, 4.630 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 281501, 22, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 354, 938)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2406)
[M::mem_pestat] mean and std.dev: (644.91, 649.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3242)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 236, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 683)
[M::mem_pestat] mean and std.dev: (257.52, 122.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 857)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 481, 1254)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3450)
[M::mem_pestat] mean and std.dev: (581.55, 505.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4548)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (140, 234, 598)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1514)
[M::mem_pestat] mean and std.dev: (375.98, 338.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1972)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 16, #reads = 1070485 mem = 536881995 peak = 939819008
[M::process] read 696122 sequences (100000250 bp) in 2.690 CPU sec, 3.245 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 281620, 33, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 528, 2101)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5903)
[M::mem_pestat] mean and std.dev: (1216.65, 1378.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7804)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 236, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 687)
[M::mem_pestat] mean and std.dev: (258.68, 123.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 862)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (505, 702, 1396)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3178)
[M::mem_pestat] mean and std.dev: (1011.22, 885.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4555)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 450, 1339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3643)
[M::mem_pestat] mean and std.dev: (803.59, 803.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4795)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696122 sequences (100000217 bp) in 2.190 CPU sec, 2.205 real sec...
[M::mem_process_seqs] Processed 696306 reads in 204.471 CPU sec, 6.639 real sec
[M::mem_process_seqs] Processed 696402 reads in 142.049 CPU sec, 4.665 real sec
sorting block 17, #reads = 1071319 mem = 536883630 peak = 939819008
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 281488, 20, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 418, 766)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1920)
[M::mem_pestat] mean and std.dev: (472.22, 377.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2497)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 237, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 690)
[M::mem_pestat] mean and std.dev: (259.59, 123.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 866)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 643, 1078)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2918)
[M::mem_pestat] mean and std.dev: (567.41, 671.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3838)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 320, 3682)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10618)
[M::mem_pestat] mean and std.dev: (1586.41, 2025.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14086)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695584 sequences (100000235 bp) in 2.581 CPU sec, 2.924 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 281979, 27, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 602, 1420)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3898)
[M::mem_pestat] mean and std.dev: (676.36, 650.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5137)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 238, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 696)
[M::mem_pestat] mean and std.dev: (260.40, 124.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 874)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (244, 600, 1189)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3079)
[M::mem_pestat] mean and std.dev: (809.81, 655.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4024)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 360, 1471)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3965)
[M::mem_pestat] mean and std.dev: (648.55, 598.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5212)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695452 sequences (100000289 bp) in 2.184 CPU sec, 2.197 real sec...
[M::mem_process_seqs] Processed 696122 reads in 205.716 CPU sec, 6.696 real sec
[M::mem_process_seqs] Processed 696122 reads in 146.316 CPU sec, 4.687 real sec
sorting block 18, #reads = 1070137 mem = 536881623 peak = 939819008
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 280240, 29, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 253, 510)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1146)
[M::mem_pestat] mean and std.dev: (307.45, 207.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1464)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 239, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 697)
[M::mem_pestat] mean and std.dev: (261.49, 124.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 875)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (400, 868, 1421)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3463)
[M::mem_pestat] mean and std.dev: (894.96, 697.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4484)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (272, 427, 1166)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2954)
[M::mem_pestat] mean and std.dev: (729.39, 684.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3848)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697456 sequences (100000055 bp) in 2.898 CPU sec, 3.236 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 281523, 31, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (261, 477, 885)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2133)
[M::mem_pestat] mean and std.dev: (558.69, 452.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2757)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 240, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 700)
[M::mem_pestat] mean and std.dev: (262.51, 125.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 879)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (29, 319, 696)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2030)
[M::mem_pestat] mean and std.dev: (387.25, 400.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2697)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 413, 1531)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4203)
[M::mem_pestat] mean and std.dev: (709.23, 710.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5539)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702016 sequences (100000034 bp) in 2.194 CPU sec, 2.197 real sec...
[M::mem_process_seqs] Processed 695584 reads in 203.850 CPU sec, 6.572 real sec
sorting block 19, #reads = 1069071 mem = 536876990 peak = 939819008
[M::mem_process_seqs] Processed 695452 reads in 147.293 CPU sec, 4.756 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 281389, 35, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (266, 356, 1134)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2870)
[M::mem_pestat] mean and std.dev: (638.45, 609.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3738)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 234, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 688)
[M::mem_pestat] mean and std.dev: (257.56, 124.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 864)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (229, 933, 1636)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4450)
[M::mem_pestat] mean and std.dev: (920.62, 789.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5857)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 269, 370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 706)
[M::mem_pestat] mean and std.dev: (269.24, 103.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 874)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701590 sequences (100000235 bp) in 2.577 CPU sec, 3.157 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 282862, 28, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (277, 392, 1025)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2521)
[M::mem_pestat] mean and std.dev: (567.93, 554.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3269)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 223, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 660)
[M::mem_pestat] mean and std.dev: (246.98, 120.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 829)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 570, 1698)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4800)
[M::mem_pestat] mean and std.dev: (746.48, 679.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6351)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 523, 795)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1927)
[M::mem_pestat] mean and std.dev: (508.95, 355.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2493)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700864 sequences (100000054 bp) in 2.216 CPU sec, 2.221 real sec...
[M::mem_process_seqs] Processed 697456 reads in 206.260 CPU sec, 6.728 real sec
sorting block 20, #reads = 1069305 mem = 536880917 peak = 944099328
[M::mem_process_seqs] Processed 702016 reads in 146.356 CPU sec, 4.700 real sec
sorting block 21, #reads = 1070494 mem = 536881448 peak = 961630208
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 283130, 17, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 494, 1293)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3461)
[M::mem_pestat] mean and std.dev: (687.64, 559.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4545)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 224, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 664)
[M::mem_pestat] mean and std.dev: (248.41, 121.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 834)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (270, 420, 2221)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6123)
[M::mem_pestat] mean and std.dev: (945.29, 975.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8074)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 612, 1203)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3163)
[M::mem_pestat] mean and std.dev: (592.12, 466.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4143)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700342 sequences (100000178 bp) in 2.611 CPU sec, 2.943 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 283125, 28, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (138, 361, 850)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2274)
[M::mem_pestat] mean and std.dev: (500.87, 493.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2986)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 225, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 668)
[M::mem_pestat] mean and std.dev: (249.97, 121.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 839)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (233, 696, 2148)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5978)
[M::mem_pestat] mean and std.dev: (1234.18, 1514.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7893)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 285, 501)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1205)
[M::mem_pestat] mean and std.dev: (311.40, 205.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1557)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700550 sequences (100000016 bp) in 2.124 CPU sec, 2.147 real sec...
[M::mem_process_seqs] Processed 701590 reads in 194.020 CPU sec, 6.243 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 283104, 24, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 374, 822)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2146)
[M::mem_pestat] mean and std.dev: (511.43, 534.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2808)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 227, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 677)
[M::mem_pestat] mean and std.dev: (251.52, 122.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 851)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (33, 1215, 1950)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5784)
[M::mem_pestat] mean and std.dev: (1269.52, 1217.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7701)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 302, 1007)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2689)
[M::mem_pestat] mean and std.dev: (452.24, 374.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3530)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699680 sequences (100000244 bp) in 2.344 CPU sec, 2.350 real sec...
[M::mem_process_seqs] Processed 700342 reads in 115.995 CPU sec, 3.761 real sec
sorting block 22, #reads = 1075601 mem = 536877460 peak = 961630208
[M::mem_process_seqs] Processed 700864 reads in 312.280 CPU sec, 10.146 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 282819, 24, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 310, 578)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1406)
[M::mem_pestat] mean and std.dev: (376.21, 231.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1820)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 227, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 680)
[M::mem_pestat] mean and std.dev: (251.84, 123.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 855)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (229, 339, 1061)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2725)
[M::mem_pestat] mean and std.dev: (536.00, 520.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3557)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (251, 528, 1010)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2528)
[M::mem_pestat] mean and std.dev: (626.08, 560.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3287)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 23, #reads = 1075154 mem = 536876175 peak = 961630208
[M::process] read 699544 sequences (100000054 bp) in 2.720 CPU sec, 3.122 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 282921, 21, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (257, 464, 912)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2222)
[M::mem_pestat] mean and std.dev: (554.29, 396.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2877)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 229, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 684)
[M::mem_pestat] mean and std.dev: (254.19, 124.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 860)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (124, 297, 1404)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3964)
[M::mem_pestat] mean and std.dev: (573.89, 575.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5244)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 242, 395)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 817)
[M::mem_pestat] mean and std.dev: (254.32, 118.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1028)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700550 reads in 220.948 CPU sec, 7.133 real sec
[M::mem_process_seqs] Processed 699680 reads in 141.564 CPU sec, 4.519 real sec
[M::process] read 699250 sequences (100000162 bp) in 2.418 CPU sec, 2.510 real sec...
sorting block 24, #reads = 1075567 mem = 536885360 peak = 961630208
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 283180, 33, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (320, 585, 1344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3392)
[M::mem_pestat] mean and std.dev: (594.37, 478.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4416)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 230, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 685)
[M::mem_pestat] mean and std.dev: (254.65, 124.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 861)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 859, 1549)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4295)
[M::mem_pestat] mean and std.dev: (973.88, 781.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5668)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 329, 1156)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3072)
[M::mem_pestat] mean and std.dev: (651.71, 708.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4030)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699032 sequences (100000080 bp) in 2.499 CPU sec, 2.720 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 282478, 27, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 390, 534)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1176)
[M::mem_pestat] mean and std.dev: (362.92, 198.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1497)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 231, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 691)
[M::mem_pestat] mean and std.dev: (255.81, 125.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 869)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 911, 2952)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8484)
[M::mem_pestat] mean and std.dev: (1225.96, 1215.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11250)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (140, 207, 452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1076)
[M::mem_pestat] mean and std.dev: (273.61, 168.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1388)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698618 sequences (100000032 bp) in 2.100 CPU sec, 2.111 real sec...
[M::mem_process_seqs] Processed 699544 reads in 193.665 CPU sec, 6.226 real sec
[M::mem_process_seqs] Processed 699250 reads in 139.117 CPU sec, 4.520 real sec
sorting block 25, #reads = 1075295 mem = 536877489 peak = 961630208
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 282615, 34, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 205, 352)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 716)
[M::mem_pestat] mean and std.dev: (199.52, 64.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 898)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 232, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 692)
[M::mem_pestat] mean and std.dev: (256.40, 125.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 870)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (255, 1314, 2237)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6201)
[M::mem_pestat] mean and std.dev: (1246.91, 1086.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8183)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 311, 1137)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3079)
[M::mem_pestat] mean and std.dev: (671.33, 810.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4050)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698260 sequences (100000025 bp) in 2.689 CPU sec, 2.985 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 282302, 20, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 324, 1442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3990)
[M::mem_pestat] mean and std.dev: (790.61, 857.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5264)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 233, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 695)
[M::mem_pestat] mean and std.dev: (257.76, 126.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 874)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (245, 475, 1238)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3224)
[M::mem_pestat] mean and std.dev: (595.79, 579.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4217)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 373, 733)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1789)
[M::mem_pestat] mean and std.dev: (411.69, 307.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2317)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697600 sequences (100000221 bp) in 2.163 CPU sec, 2.166 real sec...
[M::mem_process_seqs] Processed 699032 reads in 194.295 CPU sec, 6.313 real sec
sorting block 26, #reads = 1073385 mem = 536880840 peak = 961630208
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 282206, 25, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 389, 809)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2015)
[M::mem_pestat] mean and std.dev: (490.63, 374.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2618)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 234, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 696)
[M::mem_pestat] mean and std.dev: (258.22, 125.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 875)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (95, 443, 1120)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3170)
[M::mem_pestat] mean and std.dev: (573.58, 591.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4195)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 368, 678)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1582)
[M::mem_pestat] mean and std.dev: (387.88, 312.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2034)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697694 sequences (100000295 bp) in 2.399 CPU sec, 2.404 real sec...
[M::mem_process_seqs] Processed 698260 reads in 113.684 CPU sec, 3.713 real sec
sorting block 27, #reads = 1074363 mem = 536884398 peak = 961630208
[M::mem_process_seqs] Processed 698618 reads in 292.658 CPU sec, 9.482 real sec
[M::process] read 697504 sequences (100000272 bp) in 2.609 CPU sec, 3.149 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 281975, 35, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (240, 417, 946)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2358)
[M::mem_pestat] mean and std.dev: (548.85, 423.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3064)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 235, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 697)
[M::mem_pestat] mean and std.dev: (259.44, 126.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 876)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (229, 863, 2522)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7108)
[M::mem_pestat] mean and std.dev: (1177.00, 1647.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9401)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 417, 2210)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6210)
[M::mem_pestat] mean and std.dev: (970.20, 1055.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8210)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697694 reads in 113.070 CPU sec, 3.601 real sec
sorting block 28, #reads = 1074402 mem = 536886645 peak = 961630208
[M::process] read 697268 sequences (100000052 bp) in 2.308 CPU sec, 2.349 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 281964, 24, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 413, 1163)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3089)
[M::mem_pestat] mean and std.dev: (681.96, 632.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4052)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 235, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 696)
[M::mem_pestat] mean and std.dev: (258.63, 125.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 875)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 545, 1039)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2779)
[M::mem_pestat] mean and std.dev: (590.57, 469.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3649)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (256, 392, 1257)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3259)
[M::mem_pestat] mean and std.dev: (695.50, 707.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4260)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 282238, 22, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 393, 868)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2292)
[M::mem_pestat] mean and std.dev: (477.71, 445.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3004)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 236, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 706)
[M::mem_pestat] mean and std.dev: (260.82, 127.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 888)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (262, 792, 1322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3442)
[M::mem_pestat] mean and std.dev: (815.95, 674.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4502)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 366, 1728)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4736)
[M::mem_pestat] mean and std.dev: (836.98, 952.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6240)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697600 reads in 330.167 CPU sec, 10.679 real sec
[M::process] read 697204 sequences (100000207 bp) in 2.504 CPU sec, 2.576 real sec...
[M::mem_process_seqs] Processed 697504 reads in 168.573 CPU sec, 5.582 real sec
sorting block 29, #reads = 1072949 mem = 536876246 peak = 961630208
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 281835, 24, 24)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 354, 797)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2083)
[M::mem_pestat] mean and std.dev: (360.66, 295.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2726)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 236, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 706)
[M::mem_pestat] mean and std.dev: (260.80, 127.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 888)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (480, 906, 1727)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4221)
[M::mem_pestat] mean and std.dev: (1071.08, 836.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5468)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (238, 360, 1363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3613)
[M::mem_pestat] mean and std.dev: (661.78, 667.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4738)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696614 sequences (100000056 bp) in 2.631 CPU sec, 2.788 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 281850, 41, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 526, 792)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1962)
[M::mem_pestat] mean and std.dev: (541.69, 475.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2547)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 236, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 706)
[M::mem_pestat] mean and std.dev: (260.85, 127.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 888)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (240, 855, 1377)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3651)
[M::mem_pestat] mean and std.dev: (953.64, 922.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4788)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 229, 1111)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2931)
[M::mem_pestat] mean and std.dev: (613.91, 684.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3841)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696628 sequences (100000116 bp) in 2.109 CPU sec, 2.129 real sec...
[M::mem_process_seqs] Processed 697268 reads in 196.253 CPU sec, 6.439 real sec
sorting block 30, #reads = 1074085 mem = 536885080 peak = 961630208
[M::mem_process_seqs] Processed 697204 reads in 142.086 CPU sec, 4.570 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 281849, 14, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (273, 545, 1394)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3636)
[M::mem_pestat] mean and std.dev: (908.07, 813.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4757)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 238, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 705)
[M::mem_pestat] mean and std.dev: (262.28, 127.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 886)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 646, 1231)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3363)
[M::mem_pestat] mean and std.dev: (649.83, 496.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4429)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (243, 404, 557)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1185)
[M::mem_pestat] mean and std.dev: (406.77, 271.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1499)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 31, #reads = 1072751 mem = 536882352 peak = 961630208
[M::process] read 696094 sequences (100000136 bp) in 2.638 CPU sec, 3.021 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 281612, 19, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 285, 838)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2084)
[M::mem_pestat] mean and std.dev: (413.69, 319.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2707)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 238, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 707)
[M::mem_pestat] mean and std.dev: (262.60, 128.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 889)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (267, 543, 2266)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6264)
[M::mem_pestat] mean and std.dev: (1247.11, 1269.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8263)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (245, 454, 1763)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4799)
[M::mem_pestat] mean and std.dev: (785.16, 744.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6317)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696098 sequences (100000244 bp) in 2.173 CPU sec, 2.178 real sec...
[M::mem_process_seqs] Processed 696614 reads in 192.047 CPU sec, 6.180 real sec
[M::mem_process_seqs] Processed 696628 reads in 143.980 CPU sec, 4.619 real sec
sorting block 32, #reads = 1074014 mem = 536879682 peak = 961630208
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 281296, 20, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (372, 714, 1902)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4962)
[M::mem_pestat] mean and std.dev: (855.61, 711.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6492)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 238, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 702)
[M::mem_pestat] mean and std.dev: (261.59, 126.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 882)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (540, 861, 1884)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4572)
[M::mem_pestat] mean and std.dev: (1114.47, 1063.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5916)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 556, 1855)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5167)
[M::mem_pestat] mean and std.dev: (862.89, 957.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6823)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696012 sequences (100000019 bp) in 2.599 CPU sec, 2.928 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 281329, 24, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (250, 342, 1088)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2764)
[M::mem_pestat] mean and std.dev: (656.28, 603.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3602)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 238, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 687)
[M::mem_pestat] mean and std.dev: (259.07, 122.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 862)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 565, 1447)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3971)
[M::mem_pestat] mean and std.dev: (762.13, 669.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5233)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 406, 820)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2104)
[M::mem_pestat] mean and std.dev: (456.94, 360.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2746)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696158 sequences (100000053 bp) in 2.162 CPU sec, 2.182 real sec...
[M::mem_process_seqs] Processed 696094 reads in 196.121 CPU sec, 6.312 real sec
[M::mem_process_seqs] Processed 696098 reads in 141.267 CPU sec, 4.575 real sec
sorting block 33, #reads = 1073230 mem = 536880340 peak = 961630208
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 281461, 21, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 269, 828)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2116)
[M::mem_pestat] mean and std.dev: (369.74, 285.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2760)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 238, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 696)
[M::mem_pestat] mean and std.dev: (261.01, 125.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 874)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (275, 913, 1441)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3773)
[M::mem_pestat] mean and std.dev: (875.75, 738.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4939)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (264, 401, 1071)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2685)
[M::mem_pestat] mean and std.dev: (746.92, 790.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3910)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695708 sequences (100000178 bp) in 2.773 CPU sec, 3.295 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 280914, 35, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 305, 1372)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3716)
[M::mem_pestat] mean and std.dev: (639.35, 691.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4888)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 238, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 690)
[M::mem_pestat] mean and std.dev: (259.57, 123.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 866)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 426, 621)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1521)
[M::mem_pestat] mean and std.dev: (455.74, 366.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1971)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 367, 2059)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5735)
[M::mem_pestat] mean and std.dev: (925.09, 998.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7573)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696160 sequences (100000096 bp) in 2.166 CPU sec, 2.170 real sec...
[M::mem_process_seqs] Processed 696012 reads in 199.801 CPU sec, 6.489 real sec
sorting block 34, #reads = 1071449 mem = 536880244 peak = 961630208
[M::mem_process_seqs] Processed 696158 reads in 142.258 CPU sec, 4.652 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 280850, 25, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 364, 960)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2498)
[M::mem_pestat] mean and std.dev: (525.25, 482.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3267)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 237, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 690)
[M::mem_pestat] mean and std.dev: (259.56, 123.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 866)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (69, 884, 2669)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7869)
[M::mem_pestat] mean and std.dev: (1489.40, 1706.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10469)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 336, 693)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1667)
[M::mem_pestat] mean and std.dev: (387.20, 237.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2154)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 35, #reads = 1070594 mem = 536883721 peak = 961630208
[M::process] read 696130 sequences (100000227 bp) in 2.715 CPU sec, 2.971 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 281113, 25, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 375, 1226)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3316)
[M::mem_pestat] mean and std.dev: (650.29, 678.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4361)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 237, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 690)
[M::mem_pestat] mean and std.dev: (259.13, 123.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 866)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (288, 769, 2627)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7305)
[M::mem_pestat] mean and std.dev: (1401.92, 1435.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9644)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 278, 813)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2123)
[M::mem_pestat] mean and std.dev: (448.85, 448.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2778)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696308 sequences (100000074 bp) in 2.165 CPU sec, 2.168 real sec...
[M::mem_process_seqs] Processed 695708 reads in 200.396 CPU sec, 6.578 real sec
[M::mem_process_seqs] Processed 696160 reads in 146.796 CPU sec, 4.727 real sec
sorting block 36, #reads = 1069358 mem = 536884882 peak = 961630208
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 281652, 26, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (223, 325, 490)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1024)
[M::mem_pestat] mean and std.dev: (356.02, 195.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1291)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 237, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 687)
[M::mem_pestat] mean and std.dev: (259.06, 123.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 862)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (262, 683, 1614)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4318)
[M::mem_pestat] mean and std.dev: (1047.77, 956.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5670)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 340, 1335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3581)
[M::mem_pestat] mean and std.dev: (778.75, 839.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4704)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696198 sequences (100000047 bp) in 2.682 CPU sec, 2.995 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 281062, 30, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 475, 978)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2504)
[M::mem_pestat] mean and std.dev: (672.37, 585.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3267)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 237, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 690)
[M::mem_pestat] mean and std.dev: (259.81, 124.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 866)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (345, 761, 1172)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2826)
[M::mem_pestat] mean and std.dev: (825.21, 709.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3663)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 309, 1118)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2950)
[M::mem_pestat] mean and std.dev: (585.94, 555.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3866)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696242 sequences (100000014 bp) in 2.156 CPU sec, 2.162 real sec...
[M::mem_process_seqs] Processed 696130 reads in 197.312 CPU sec, 6.354 real sec
[M::mem_process_seqs] Processed 696308 reads in 141.751 CPU sec, 4.582 real sec
sorting block 37, #reads = 1071816 mem = 536882315 peak = 961630208
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 281213, 23, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 372, 594)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1352)
[M::mem_pestat] mean and std.dev: (325.81, 166.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1731)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 237, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 693)
[M::mem_pestat] mean and std.dev: (259.95, 124.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 870)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (420, 1025, 1635)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4065)
[M::mem_pestat] mean and std.dev: (971.14, 792.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5280)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 363, 812)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2002)
[M::mem_pestat] mean and std.dev: (444.38, 368.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2597)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696836 sequences (100000037 bp) in 2.829 CPU sec, 3.124 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 280811, 28, 24)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 273, 794)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1956)
[M::mem_pestat] mean and std.dev: (421.72, 344.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2537)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 237, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 690)
[M::mem_pestat] mean and std.dev: (259.47, 124.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 866)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (548, 586, 1273)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2723)
[M::mem_pestat] mean and std.dev: (759.62, 621.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3448)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 392, 1038)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2712)
[M::mem_pestat] mean and std.dev: (538.52, 422.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3549)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696352 sequences (100000224 bp) in 2.198 CPU sec, 2.205 real sec...
[M::mem_process_seqs] Processed 696198 reads in 202.417 CPU sec, 6.549 real sec
[M::mem_process_seqs] Processed 696242 reads in 144.057 CPU sec, 4.667 real sec
sorting block 38, #reads = 1071658 mem = 536879871 peak = 961630208
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 281612, 20, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (236, 448, 1506)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4046)
[M::mem_pestat] mean and std.dev: (954.63, 1098.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5350)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 236, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 689)
[M::mem_pestat] mean and std.dev: (258.32, 123.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 865)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (134, 356, 1838)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5246)
[M::mem_pestat] mean and std.dev: (927.32, 1151.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6950)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 257, 813)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2047)
[M::mem_pestat] mean and std.dev: (417.68, 439.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2664)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696506 sequences (100000142 bp) in 2.640 CPU sec, 2.898 real sec...
sorting block 39, #reads = 1070149 mem = 536881057 peak = 961630208
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 281590, 17, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 342, 1111)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2955)
[M::mem_pestat] mean and std.dev: (611.90, 604.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3877)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 237, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 693)
[M::mem_pestat] mean and std.dev: (259.97, 124.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 870)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (259, 463, 839)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1999)
[M::mem_pestat] mean and std.dev: (537.12, 411.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2579)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 399, 873)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2305)
[M::mem_pestat] mean and std.dev: (480.86, 513.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3021)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696434 sequences (100000238 bp) in 2.232 CPU sec, 2.313 real sec...
[M::mem_process_seqs] Processed 696836 reads in 205.051 CPU sec, 6.702 real sec
[M::mem_process_seqs] Processed 696352 reads in 148.093 CPU sec, 4.787 real sec
sorting block 40, #reads = 1070792 mem = 536880607 peak = 961630208
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 281548, 34, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 490, 1251)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3357)
[M::mem_pestat] mean and std.dev: (798.45, 903.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4411)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 237, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 701)
[M::mem_pestat] mean and std.dev: (260.93, 126.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 881)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 916, 2415)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6891)
[M::mem_pestat] mean and std.dev: (1684.88, 1996.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9671)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 475, 1130)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2972)
[M::mem_pestat] mean and std.dev: (610.02, 503.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3893)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698198 sequences (100000091 bp) in 2.632 CPU sec, 3.038 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 280604, 29, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 232, 1137)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3089)
[M::mem_pestat] mean and std.dev: (488.34, 601.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4065)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 237, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 701)
[M::mem_pestat] mean and std.dev: (261.00, 126.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 881)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 485, 1159)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3087)
[M::mem_pestat] mean and std.dev: (759.52, 760.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4051)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (245, 389, 1599)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4307)
[M::mem_pestat] mean and std.dev: (972.55, 1045.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5661)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702954 sequences (100000052 bp) in 2.186 CPU sec, 2.193 real sec...
[M::mem_process_seqs] Processed 696506 reads in 201.949 CPU sec, 6.487 real sec
[M::mem_process_seqs] Processed 696434 reads in 146.881 CPU sec, 4.906 real sec
sorting block 41, #reads = 1069544 mem = 536880062 peak = 961630208
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 281755, 23, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 666, 931)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2391)
[M::mem_pestat] mean and std.dev: (602.97, 496.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3121)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 233, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 690)
[M::mem_pestat] mean and std.dev: (257.02, 124.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 867)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (131, 870, 1858)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5312)
[M::mem_pestat] mean and std.dev: (1002.96, 1013.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7039)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (251, 432, 1187)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3059)
[M::mem_pestat] mean and std.dev: (610.51, 459.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3995)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702562 sequences (100000059 bp) in 2.563 CPU sec, 3.297 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 283306, 48, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 273, 1029)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2721)
[M::mem_pestat] mean and std.dev: (498.69, 467.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3567)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 220, 318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 650)
[M::mem_pestat] mean and std.dev: (244.69, 119.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 816)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (483, 723, 2321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5997)
[M::mem_pestat] mean and std.dev: (1170.49, 939.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7835)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 275, 443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 951)
[M::mem_pestat] mean and std.dev: (281.61, 140.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1205)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702418 sequences (100000036 bp) in 2.215 CPU sec, 2.222 real sec...
[M::mem_process_seqs] Processed 698198 reads in 207.349 CPU sec, 6.946 real sec
sorting block 42, #reads = 1065790 mem = 536884292 peak = 961630208
[M::mem_process_seqs] Processed 702954 reads in 143.460 CPU sec, 4.615 real sec
[M::process] read 701866 sequences (100000019 bp) in 2.964 CPU sec, 3.338 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 283168, 13, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (269, 389, 695)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1547)
[M::mem_pestat] mean and std.dev: (353.40, 146.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1973)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 221, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 657)
[M::mem_pestat] mean and std.dev: (246.06, 119.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 825)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 1121, 2314)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6586)
[M::mem_pestat] mean and std.dev: (1115.23, 1009.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8722)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 475, 782)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1968)
[M::mem_pestat] mean and std.dev: (412.88, 250.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2561)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701522 sequences (100000100 bp) in 2.229 CPU sec, 2.237 real sec...
[M::mem_process_seqs] Processed 702418 reads in 117.758 CPU sec, 3.763 real sec
sorting block 43, #reads = 1075438 mem = 536887999 peak = 961630208
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 283703, 26, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 369, 1065)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2841)
[M::mem_pestat] mean and std.dev: (591.60, 535.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3729)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 221, 320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 656)
[M::mem_pestat] mean and std.dev: (245.47, 119.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 824)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (435, 1246, 3484)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9582)
[M::mem_pestat] mean and std.dev: (2318.88, 2607.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12750)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (282, 437, 1027)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2517)
[M::mem_pestat] mean and std.dev: (757.92, 658.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3390)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 283650, 18, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 365, 938)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2432)
[M::mem_pestat] mean and std.dev: (549.53, 565.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3179)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 222, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 657)
[M::mem_pestat] mean and std.dev: (246.55, 119.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 825)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (73, 212, 1231)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3547)
[M::mem_pestat] mean and std.dev: (517.88, 520.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4705)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 261, 735)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1929)
[M::mem_pestat] mean and std.dev: (459.29, 447.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2526)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702562 reads in 306.710 CPU sec, 9.949 real sec
[M::process] read 701718 sequences (100000215 bp) in 2.366 CPU sec, 2.577 real sec...
[M::mem_process_seqs] Processed 701866 reads in 168.403 CPU sec, 5.651 real sec
sorting block 44, #reads = 1075889 mem = 536878130 peak = 976424960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 283473, 36, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 252, 537)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1193)
[M::mem_pestat] mean and std.dev: (231.67, 94.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1521)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 223, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 666)
[M::mem_pestat] mean and std.dev: (248.31, 121.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 837)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (516, 926, 2519)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6525)
[M::mem_pestat] mean and std.dev: (1509.83, 1420.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8528)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 395, 649)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1535)
[M::mem_pestat] mean and std.dev: (396.71, 264.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1978)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701384 sequences (100000258 bp) in 2.840 CPU sec, 3.194 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 283526, 16, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 406, 1321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3587)
[M::mem_pestat] mean and std.dev: (708.74, 724.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4720)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 224, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 667)
[M::mem_pestat] mean and std.dev: (248.70, 121.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 838)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 767, 1308)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3630)
[M::mem_pestat] mean and std.dev: (613.36, 483.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4791)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 343, 854)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2156)
[M::mem_pestat] mean and std.dev: (383.86, 301.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2807)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700624 sequences (100000041 bp) in 2.160 CPU sec, 2.168 real sec...
[M::mem_process_seqs] Processed 701522 reads in 197.845 CPU sec, 6.515 real sec
sorting block 45, #reads = 1075286 mem = 536878778 peak = 976424960
[M::mem_process_seqs] Processed 701718 reads in 143.199 CPU sec, 4.586 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 283245, 29, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 234, 808)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2048)
[M::mem_pestat] mean and std.dev: (367.00, 374.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2668)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 224, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 664)
[M::mem_pestat] mean and std.dev: (248.73, 121.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 834)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (371, 702, 1041)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2381)
[M::mem_pestat] mean and std.dev: (795.89, 621.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3284)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 228, 409)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 899)
[M::mem_pestat] mean and std.dev: (251.45, 118.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1144)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 46, #reads = 1075557 mem = 536879249 peak = 1000259584
[M::process] read 699834 sequences (100000206 bp) in 2.678 CPU sec, 3.254 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 283601, 23, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 379, 913)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2405)
[M::mem_pestat] mean and std.dev: (489.45, 464.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3151)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 226, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 674)
[M::mem_pestat] mean and std.dev: (251.28, 123.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 847)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (406, 713, 3053)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8347)
[M::mem_pestat] mean and std.dev: (1709.13, 1915.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10994)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (238, 394, 1065)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2719)
[M::mem_pestat] mean and std.dev: (617.39, 485.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3546)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700066 sequences (100000004 bp) in 2.185 CPU sec, 2.219 real sec...
[M::mem_process_seqs] Processed 701384 reads in 194.580 CPU sec, 6.257 real sec
[M::mem_process_seqs] Processed 700624 reads in 140.087 CPU sec, 4.502 real sec
sorting block 47, #reads = 1073951 mem = 536876542 peak = 1000259584
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 283077, 42, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 464, 693)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1737)
[M::mem_pestat] mean and std.dev: (436.07, 314.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2259)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 229, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 684)
[M::mem_pestat] mean and std.dev: (253.93, 124.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 860)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (503, 705, 1652)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3950)
[M::mem_pestat] mean and std.dev: (907.77, 754.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5099)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (374, 522, 1470)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3662)
[M::mem_pestat] mean and std.dev: (592.38, 430.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4758)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698868 sequences (100000039 bp) in 2.692 CPU sec, 2.992 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 283160, 24, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 296, 437)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 963)
[M::mem_pestat] mean and std.dev: (269.00, 121.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1226)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 227, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 675)
[M::mem_pestat] mean and std.dev: (251.92, 122.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 848)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (467, 818, 2195)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5651)
[M::mem_pestat] mean and std.dev: (1283.50, 1198.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7379)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 253, 1596)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4396)
[M::mem_pestat] mean and std.dev: (779.90, 844.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5796)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699084 sequences (100000236 bp) in 2.121 CPU sec, 2.167 real sec...
[M::mem_process_seqs] Processed 699834 reads in 199.219 CPU sec, 6.505 real sec
[M::mem_process_seqs] Processed 700066 reads in 139.097 CPU sec, 4.557 real sec
sorting block 48, #reads = 1074984 mem = 536879421 peak = 1000259584
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 282686, 12, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 724, 1420)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3920)
[M::mem_pestat] mean and std.dev: (996.56, 1064.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5254)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 230, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 691)
[M::mem_pestat] mean and std.dev: (255.77, 125.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 869)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 846, 2401)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6863)
[M::mem_pestat] mean and std.dev: (972.45, 992.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9094)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 599, 1146)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3068)
[M::mem_pestat] mean and std.dev: (623.42, 502.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4029)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698676 sequences (100000097 bp) in 2.761 CPU sec, 3.061 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 282725, 19, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 447, 963)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2453)
[M::mem_pestat] mean and std.dev: (516.00, 546.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3198)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 230, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 688)
[M::mem_pestat] mean and std.dev: (255.52, 125.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 865)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (495, 1084, 1369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3117)
[M::mem_pestat] mean and std.dev: (1026.58, 742.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3995)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 412, 1158)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3044)
[M::mem_pestat] mean and std.dev: (650.50, 619.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3987)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698530 sequences (100000018 bp) in 2.183 CPU sec, 2.188 real sec...
[M::mem_process_seqs] Processed 698868 reads in 195.397 CPU sec, 6.397 real sec
sorting block 49, #reads = 1074711 mem = 536878804 peak = 1026023424
[M::mem_process_seqs] Processed 699084 reads in 139.005 CPU sec, 4.583 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 282568, 30, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 401, 2400)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6828)
[M::mem_pestat] mean and std.dev: (1016.78, 1422.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9042)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 233, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 695)
[M::mem_pestat] mean and std.dev: (257.42, 125.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 874)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (228, 540, 1128)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2928)
[M::mem_pestat] mean and std.dev: (605.89, 549.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3828)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 279, 845)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2123)
[M::mem_pestat] mean and std.dev: (510.21, 518.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2762)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 50, #reads = 1074327 mem = 536878936 peak = 1026023424
[M::process] read 698562 sequences (100000226 bp) in 2.734 CPU sec, 2.898 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 282192, 28, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 459, 1457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4009)
[M::mem_pestat] mean and std.dev: (783.16, 684.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5285)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 233, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 698)
[M::mem_pestat] mean and std.dev: (258.39, 127.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 878)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (587, 854, 2138)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5240)
[M::mem_pestat] mean and std.dev: (1153.58, 916.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6791)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 306, 697)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1655)
[M::mem_pestat] mean and std.dev: (362.47, 305.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2134)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698112 sequences (100000048 bp) in 2.183 CPU sec, 2.187 real sec...
[M::mem_process_seqs] Processed 698676 reads in 196.115 CPU sec, 6.519 real sec
[M::mem_process_seqs] Processed 698530 reads in 139.494 CPU sec, 4.683 real sec
sorting block 51, #reads = 1074240 mem = 536886193 peak = 1026023424
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 282360, 11, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 311, 596)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1400)
[M::mem_pestat] mean and std.dev: (359.29, 278.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1802)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 232, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 695)
[M::mem_pestat] mean and std.dev: (257.78, 126.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 874)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (456, 678, 861)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1671)
[M::mem_pestat] mean and std.dev: (622.30, 383.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2156)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 279, 720)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1850)
[M::mem_pestat] mean and std.dev: (353.17, 307.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2415)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697986 sequences (100000060 bp) in 2.726 CPU sec, 3.148 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 282470, 19, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 243, 480)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1134)
[M::mem_pestat] mean and std.dev: (251.88, 156.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1461)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 233, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 696)
[M::mem_pestat] mean and std.dev: (258.21, 126.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 875)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (493, 576, 3317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8965)
[M::mem_pestat] mean and std.dev: (1605.84, 1916.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11789)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 221, 302)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 612)
[M::mem_pestat] mean and std.dev: (211.53, 81.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 767)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697718 sequences (100000202 bp) in 2.151 CPU sec, 2.175 real sec...
[M::mem_process_seqs] Processed 698562 reads in 198.859 CPU sec, 6.573 real sec
[M::mem_process_seqs] Processed 698112 reads in 140.615 CPU sec, 4.676 real sec
sorting block 52, #reads = 1074296 mem = 536877192 peak = 1026023424
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 282024, 29, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 359, 1459)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4011)
[M::mem_pestat] mean and std.dev: (673.33, 761.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5287)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 234, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 696)
[M::mem_pestat] mean and std.dev: (258.53, 126.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 875)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (308, 751, 6058)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 17558)
[M::mem_pestat] mean and std.dev: (2502.45, 2814.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 23308)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 318, 597)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1385)
[M::mem_pestat] mean and std.dev: (395.00, 236.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1779)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697892 sequences (100000093 bp) in 2.698 CPU sec, 2.976 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 281878, 33, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 317, 1637)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4615)
[M::mem_pestat] mean and std.dev: (847.90, 968.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6104)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 234, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 699)
[M::mem_pestat] mean and std.dev: (259.36, 127.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 879)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (131, 529, 1447)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4079)
[M::mem_pestat] mean and std.dev: (846.76, 790.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5395)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 252, 654)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1670)
[M::mem_pestat] mean and std.dev: (359.52, 289.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2178)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697670 sequences (100000024 bp) in 2.195 CPU sec, 2.239 real sec...
[M::mem_process_seqs] Processed 697986 reads in 197.396 CPU sec, 6.483 real sec
sorting block 53, #reads = 1074974 mem = 536881081 peak = 1026023424
[M::mem_process_seqs] Processed 697718 reads in 139.413 CPU sec, 4.560 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 282073, 29, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 316, 664)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1640)
[M::mem_pestat] mean and std.dev: (394.98, 387.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2128)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 232, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 681)
[M::mem_pestat] mean and std.dev: (255.90, 123.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 855)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (451, 819, 1466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3496)
[M::mem_pestat] mean and std.dev: (999.24, 814.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4511)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 283, 757)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1869)
[M::mem_pestat] mean and std.dev: (433.38, 417.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2425)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 54, #reads = 1073691 mem = 536890330 peak = 1046577152
[M::process] read 698128 sequences (100000045 bp) in 2.702 CPU sec, 3.049 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 282410, 30, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 245, 905)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2391)
[M::mem_pestat] mean and std.dev: (514.51, 584.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3134)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 232, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 672)
[M::mem_pestat] mean and std.dev: (254.29, 121.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 843)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (566, 1100, 1470)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3278)
[M::mem_pestat] mean and std.dev: (1214.97, 851.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4620)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (285, 628, 1663)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4419)
[M::mem_pestat] mean and std.dev: (952.91, 930.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5797)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697478 sequences (100000085 bp) in 2.339 CPU sec, 2.405 real sec...
[M::mem_process_seqs] Processed 697892 reads in 198.487 CPU sec, 6.476 real sec
[M::mem_process_seqs] Processed 697670 reads in 138.864 CPU sec, 4.528 real sec
sorting block 55, #reads = 1073546 mem = 536877096 peak = 1046577152
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 282138, 19, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (225, 367, 1716)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4698)
[M::mem_pestat] mean and std.dev: (874.63, 887.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6189)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 231, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 677)
[M::mem_pestat] mean and std.dev: (254.85, 123.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 850)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (89, 479, 1707)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4943)
[M::mem_pestat] mean and std.dev: (788.78, 1045.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6561)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (236, 493, 984)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2480)
[M::mem_pestat] mean and std.dev: (583.55, 472.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3228)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696400 sequences (100000090 bp) in 2.628 CPU sec, 2.803 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 281878, 30, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 300, 744)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1816)
[M::mem_pestat] mean and std.dev: (387.81, 337.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2352)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 234, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 691)
[M::mem_pestat] mean and std.dev: (258.20, 125.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 868)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 528, 1071)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2865)
[M::mem_pestat] mean and std.dev: (595.68, 537.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3762)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (287, 481, 813)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1865)
[M::mem_pestat] mean and std.dev: (505.91, 339.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2391)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696316 sequences (100000237 bp) in 2.178 CPU sec, 2.189 real sec...
[M::mem_process_seqs] Processed 698128 reads in 199.686 CPU sec, 6.504 real sec
[M::mem_process_seqs] Processed 697478 reads in 141.086 CPU sec, 4.580 real sec
sorting block 56, #reads = 1072853 mem = 536887051 peak = 1046577152
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 281740, 25, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 370, 866)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2210)
[M::mem_pestat] mean and std.dev: (507.36, 427.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2882)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 238, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 699)
[M::mem_pestat] mean and std.dev: (261.18, 126.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 878)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (313, 462, 1995)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5359)
[M::mem_pestat] mean and std.dev: (878.68, 857.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7041)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 445, 2453)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6903)
[M::mem_pestat] mean and std.dev: (611.84, 909.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9128)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696930 sequences (100000138 bp) in 2.726 CPU sec, 2.999 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 281559, 19, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (259, 398, 1298)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3376)
[M::mem_pestat] mean and std.dev: (776.32, 839.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4415)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 238, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 699)
[M::mem_pestat] mean and std.dev: (260.98, 126.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 878)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 828, 1028)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2772)
[M::mem_pestat] mean and std.dev: (525.88, 387.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3644)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (231, 512, 856)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2106)
[M::mem_pestat] mean and std.dev: (534.00, 461.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2731)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696542 sequences (100000196 bp) in 2.196 CPU sec, 2.312 real sec...
[M::mem_process_seqs] Processed 696400 reads in 201.892 CPU sec, 6.609 real sec
sorting block 57, #reads = 1072467 mem = 536882317 peak = 1046577152
[M::mem_process_seqs] Processed 696316 reads in 141.444 CPU sec, 4.590 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 281698, 22, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 446, 951)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2459)
[M::mem_pestat] mean and std.dev: (585.14, 487.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3213)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 237, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 701)
[M::mem_pestat] mean and std.dev: (260.41, 126.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 881)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (429, 635, 1307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3063)
[M::mem_pestat] mean and std.dev: (880.32, 684.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3941)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 427, 835)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2143)
[M::mem_pestat] mean and std.dev: (514.23, 434.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2797)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 58, #reads = 1071286 mem = 536879562 peak = 1046577152
[M::process] read 696348 sequences (100000056 bp) in 2.684 CPU sec, 2.887 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 281375, 16, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (141, 357, 573)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1437)
[M::mem_pestat] mean and std.dev: (371.22, 298.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1869)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 237, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 699)
[M::mem_pestat] mean and std.dev: (261.07, 126.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 878)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (69, 572, 1578)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4596)
[M::mem_pestat] mean and std.dev: (921.56, 973.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6105)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (289, 406, 809)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1849)
[M::mem_pestat] mean and std.dev: (526.47, 357.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2369)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696320 sequences (100000198 bp) in 2.196 CPU sec, 2.212 real sec...
[M::mem_process_seqs] Processed 696930 reads in 202.905 CPU sec, 6.561 real sec
[M::mem_process_seqs] Processed 696542 reads in 144.484 CPU sec, 4.639 real sec
sorting block 59, #reads = 1072086 mem = 536881513 peak = 1046577152
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 281412, 28, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (276, 443, 1003)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2457)
[M::mem_pestat] mean and std.dev: (486.85, 480.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3184)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 237, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 698)
[M::mem_pestat] mean and std.dev: (260.61, 126.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 877)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (349, 588, 1735)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4507)
[M::mem_pestat] mean and std.dev: (759.85, 615.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5893)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (249, 440, 1447)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3843)
[M::mem_pestat] mean and std.dev: (644.03, 714.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5041)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696296 sequences (100000180 bp) in 2.692 CPU sec, 2.895 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 281826, 25, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 362, 1758)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4910)
[M::mem_pestat] mean and std.dev: (1111.95, 1339.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6486)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 237, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 696)
[M::mem_pestat] mean and std.dev: (260.82, 126.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 874)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (100, 492, 901)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2503)
[M::mem_pestat] mean and std.dev: (396.81, 325.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3304)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 922, 1116)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2958)
[M::mem_pestat] mean and std.dev: (714.77, 546.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3879)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697168 sequences (100000190 bp) in 2.333 CPU sec, 2.334 real sec...
[M::mem_process_seqs] Processed 696348 reads in 204.302 CPU sec, 6.673 real sec
[M::mem_process_seqs] Processed 696320 reads in 143.812 CPU sec, 4.614 real sec
sorting block 60, #reads = 1069952 mem = 536877980 peak = 1046577152
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 281513, 27, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (282, 659, 1333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3435)
[M::mem_pestat] mean and std.dev: (804.56, 734.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4486)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 237, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 698)
[M::mem_pestat] mean and std.dev: (260.51, 125.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 877)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (422, 640, 2269)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5963)
[M::mem_pestat] mean and std.dev: (1224.89, 1152.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7810)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 258, 406)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 898)
[M::mem_pestat] mean and std.dev: (282.26, 140.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1144)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696128 sequences (100000169 bp) in 2.549 CPU sec, 3.023 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 282221, 30, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 378, 790)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1968)
[M::mem_pestat] mean and std.dev: (443.22, 294.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2557)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 234, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 691)
[M::mem_pestat] mean and std.dev: (257.99, 124.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 868)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (464, 1108, 2182)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5618)
[M::mem_pestat] mean and std.dev: (1423.23, 1238.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7336)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 334, 1013)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2729)
[M::mem_pestat] mean and std.dev: (497.14, 505.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3587)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695880 sequences (100000049 bp) in 2.216 CPU sec, 2.224 real sec...
[M::mem_process_seqs] Processed 696296 reads in 202.791 CPU sec, 6.618 real sec
sorting block 61, #reads = 1070352 mem = 536879834 peak = 1046577152
[M::mem_process_seqs] Processed 697168 reads in 148.247 CPU sec, 4.822 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 281535, 35, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 373, 1658)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4598)
[M::mem_pestat] mean and std.dev: (842.08, 1030.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6068)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 239, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 708)
[M::mem_pestat] mean and std.dev: (263.20, 128.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 890)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (259, 484, 1024)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2554)
[M::mem_pestat] mean and std.dev: (679.47, 623.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3319)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (297, 635, 1899)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5103)
[M::mem_pestat] mean and std.dev: (1062.00, 995.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6705)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700814 sequences (100000256 bp) in 2.676 CPU sec, 3.084 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 280861, 34, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (251, 404, 1124)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2870)
[M::mem_pestat] mean and std.dev: (678.58, 521.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3743)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 241, 347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 715)
[M::mem_pestat] mean and std.dev: (264.79, 129.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 899)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (112, 424, 1089)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3043)
[M::mem_pestat] mean and std.dev: (553.45, 487.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4020)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 415, 1668)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4698)
[M::mem_pestat] mean and std.dev: (752.98, 941.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6213)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702058 sequences (100000027 bp) in 2.180 CPU sec, 2.189 real sec...
[M::mem_process_seqs] Processed 696128 reads in 204.181 CPU sec, 6.639 real sec
sorting block 62, #reads = 1070039 mem = 536877267 peak = 1046577152
[M::mem_process_seqs] Processed 695880 reads in 144.905 CPU sec, 4.706 real sec
sorting block 63, #reads = 1070515 mem = 536879876 peak = 1066745856
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 283163, 22, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 396, 1265)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3421)
[M::mem_pestat] mean and std.dev: (794.45, 877.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4499)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 226, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 668)
[M::mem_pestat] mean and std.dev: (249.90, 121.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 839)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (124, 610, 946)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2590)
[M::mem_pestat] mean and std.dev: (527.80, 387.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3412)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 347, 1513)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4185)
[M::mem_pestat] mean and std.dev: (713.78, 619.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5521)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701948 sequences (100000067 bp) in 2.636 CPU sec, 3.023 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 282903, 32, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 616, 861)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2185)
[M::mem_pestat] mean and std.dev: (580.48, 462.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2847)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 221, 320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 654)
[M::mem_pestat] mean and std.dev: (245.79, 119.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 821)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 258, 2710)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7796)
[M::mem_pestat] mean and std.dev: (1161.69, 1823.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10339)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 394, 940)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2404)
[M::mem_pestat] mean and std.dev: (545.03, 440.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3136)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701666 sequences (100000078 bp) in 2.162 CPU sec, 2.197 real sec...
[M::mem_process_seqs] Processed 700814 reads in 204.021 CPU sec, 6.624 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 283507, 23, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (241, 471, 864)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2110)
[M::mem_pestat] mean and std.dev: (522.72, 313.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2733)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 222, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 657)
[M::mem_pestat] mean and std.dev: (246.83, 120.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 825)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (254, 491, 1110)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2822)
[M::mem_pestat] mean and std.dev: (693.95, 537.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3678)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (283, 448, 2099)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5731)
[M::mem_pestat] mean and std.dev: (1023.55, 1004.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7547)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701358 sequences (100000019 bp) in 2.298 CPU sec, 2.345 real sec...
[M::mem_process_seqs] Processed 701948 reads in 114.869 CPU sec, 3.779 real sec
sorting block 64, #reads = 1070385 mem = 536876919 peak = 1066745856
[M::mem_process_seqs] Processed 702058 reads in 300.222 CPU sec, 9.758 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 283107, 15, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 416, 695)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1773)
[M::mem_pestat] mean and std.dev: (415.63, 303.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2312)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 222, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 660)
[M::mem_pestat] mean and std.dev: (247.27, 120.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 829)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (622, 887, 3186)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8314)
[M::mem_pestat] mean and std.dev: (1552.14, 1457.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10878)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (245, 327, 819)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1967)
[M::mem_pestat] mean and std.dev: (503.50, 402.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2541)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 65, #reads = 1075872 mem = 536881007 peak = 1068630016
[M::process] read 701288 sequences (100000168 bp) in 2.494 CPU sec, 3.037 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 283352, 28, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 421, 2326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6644)
[M::mem_pestat] mean and std.dev: (1216.03, 1654.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8803)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 225, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 664)
[M::mem_pestat] mean and std.dev: (248.49, 120.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 834)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 446, 1036)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2802)
[M::mem_pestat] mean and std.dev: (597.12, 611.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3685)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 207, 446)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1016)
[M::mem_pestat] mean and std.dev: (244.88, 123.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1301)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701666 reads in 220.440 CPU sec, 7.231 real sec
[M::mem_process_seqs] Processed 701358 reads in 138.776 CPU sec, 4.578 real sec
[M::process] read 701356 sequences (100000109 bp) in 2.536 CPU sec, 2.709 real sec...
sorting block 66, #reads = 1078459 mem = 536881255 peak = 1068630016
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 283376, 17, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 421, 771)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1957)
[M::mem_pestat] mean and std.dev: (544.30, 430.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2550)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 224, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 664)
[M::mem_pestat] mean and std.dev: (248.64, 121.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 834)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (984, 1179, 1312)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (328, 1968)
[M::mem_pestat] mean and std.dev: (1207.31, 130.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2296)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 290, 697)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1719)
[M::mem_pestat] mean and std.dev: (412.59, 321.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2230)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701272 sequences (100000040 bp) in 3.026 CPU sec, 3.508 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 282803, 38, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 442, 1152)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3038)
[M::mem_pestat] mean and std.dev: (634.26, 554.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3981)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 224, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 667)
[M::mem_pestat] mean and std.dev: (248.90, 121.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 838)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 493, 954)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2490)
[M::mem_pestat] mean and std.dev: (512.97, 460.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3258)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 412, 702)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1698)
[M::mem_pestat] mean and std.dev: (471.87, 321.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2196)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701288 reads in 191.664 CPU sec, 6.227 real sec
[M::process] read 700648 sequences (100000179 bp) in 2.098 CPU sec, 2.138 real sec...
[M::mem_process_seqs] Processed 701356 reads in 138.769 CPU sec, 4.600 real sec
sorting block 67, #reads = 1076151 mem = 536878833 peak = 1068630016
[M::process] read 700286 sequences (100000100 bp) in 2.803 CPU sec, 3.140 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 283350, 19, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 348, 663)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1683)
[M::mem_pestat] mean and std.dev: (345.56, 296.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2193)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 225, 327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 671)
[M::mem_pestat] mean and std.dev: (250.72, 122.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 843)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (393, 767, 2676)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7242)
[M::mem_pestat] mean and std.dev: (1365.21, 1358.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9525)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 309, 512)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1098)
[M::mem_pestat] mean and std.dev: (322.50, 167.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1391)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700564 sequences (100000125 bp) in 2.158 CPU sec, 2.163 real sec...
[M::mem_process_seqs] Processed 700648 reads in 116.382 CPU sec, 3.708 real sec
sorting block 68, #reads = 1076735 mem = 536877685 peak = 1068630016
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 283895, 18, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (233, 386, 1211)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3167)
[M::mem_pestat] mean and std.dev: (691.19, 756.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4145)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 223, 323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 663)
[M::mem_pestat] mean and std.dev: (248.02, 121.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 833)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (268, 947, 2783)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7813)
[M::mem_pestat] mean and std.dev: (1461.94, 1547.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10328)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (377, 866, 3157)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8717)
[M::mem_pestat] mean and std.dev: (1173.79, 1332.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11497)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 282595, 27, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 204, 544)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1330)
[M::mem_pestat] mean and std.dev: (307.79, 218.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1723)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 227, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 672)
[M::mem_pestat] mean and std.dev: (251.84, 123.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 844)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 762, 1573)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4301)
[M::mem_pestat] mean and std.dev: (957.26, 799.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5665)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 281, 442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 926)
[M::mem_pestat] mean and std.dev: (254.07, 117.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1168)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701272 reads in 303.206 CPU sec, 9.932 real sec
[M::process] read 699852 sequences (100000193 bp) in 2.394 CPU sec, 2.479 real sec...
[M::mem_process_seqs] Processed 700286 reads in 167.816 CPU sec, 5.485 real sec
sorting block 69, #reads = 1076502 mem = 536880731 peak = 1068630016
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 283160, 19, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 318, 1051)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2723)
[M::mem_pestat] mean and std.dev: (527.68, 470.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3559)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 227, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 674)
[M::mem_pestat] mean and std.dev: (251.02, 122.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 847)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 521, 1273)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3509)
[M::mem_pestat] mean and std.dev: (861.21, 933.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4627)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (291, 581, 1872)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5034)
[M::mem_pestat] mean and std.dev: (941.71, 1028.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6615)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699524 sequences (100000177 bp) in 2.705 CPU sec, 2.927 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 283345, 9, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 452, 1342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3594)
[M::mem_pestat] mean and std.dev: (734.57, 677.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4720)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 228, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 681)
[M::mem_pestat] mean and std.dev: (253.08, 123.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 856)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (251, 463, 1412)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3734)
[M::mem_pestat] mean and std.dev: (883.49, 896.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4895)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 699080 sequences (100000041 bp) in 2.232 CPU sec, 2.314 real sec...
[M::mem_process_seqs] Processed 700564 reads in 197.462 CPU sec, 6.579 real sec
sorting block 70, #reads = 1073760 mem = 536890382 peak = 1068630016
[M::mem_process_seqs] Processed 699852 reads in 139.437 CPU sec, 4.528 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 282554, 29, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 339, 965)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2465)
[M::mem_pestat] mean and std.dev: (566.34, 471.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3215)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 228, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 681)
[M::mem_pestat] mean and std.dev: (253.46, 124.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 856)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 497, 1374)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3826)
[M::mem_pestat] mean and std.dev: (715.44, 727.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5052)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 322, 681)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1603)
[M::mem_pestat] mean and std.dev: (477.02, 399.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2073)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 71, #reads = 1076182 mem = 536879236 peak = 1068630016
[M::process] read 698918 sequences (100000019 bp) in 2.628 CPU sec, 3.058 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (22, 282482, 21, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 536, 2542)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7276)
[M::mem_pestat] mean and std.dev: (1614.52, 2313.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10869)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 230, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 685)
[M::mem_pestat] mean and std.dev: (255.03, 124.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 861)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 354, 864)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2192)
[M::mem_pestat] mean and std.dev: (453.79, 426.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2856)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (273, 451, 510)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 984)
[M::mem_pestat] mean and std.dev: (364.84, 179.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1221)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698878 sequences (100000197 bp) in 2.197 CPU sec, 2.228 real sec...
[M::mem_process_seqs] Processed 699524 reads in 192.877 CPU sec, 6.244 real sec
[M::mem_process_seqs] Processed 699080 reads in 138.150 CPU sec, 4.500 real sec
sorting block 72, #reads = 1074028 mem = 536879583 peak = 1068630016
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (21, 282773, 24, 73)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 272, 348)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 652)
[M::mem_pestat] mean and std.dev: (277.47, 131.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 805)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 232, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 692)
[M::mem_pestat] mean and std.dev: (256.48, 125.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 870)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (126, 390, 703)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1857)
[M::mem_pestat] mean and std.dev: (432.05, 455.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2434)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (237, 448, 974)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2448)
[M::mem_pestat] mean and std.dev: (699.68, 612.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3185)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698868 sequences (100000067 bp) in 2.641 CPU sec, 3.204 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 282717, 26, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 433, 1133)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3037)
[M::mem_pestat] mean and std.dev: (579.88, 535.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3989)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 231, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 689)
[M::mem_pestat] mean and std.dev: (256.35, 126.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 866)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 426, 1726)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4736)
[M::mem_pestat] mean and std.dev: (1194.54, 1348.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6588)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 463, 589)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1339)
[M::mem_pestat] mean and std.dev: (391.66, 205.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1714)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698458 sequences (100000249 bp) in 2.040 CPU sec, 2.065 real sec...
[M::mem_process_seqs] Processed 698918 reads in 196.209 CPU sec, 6.453 real sec
[M::mem_process_seqs] Processed 698878 reads in 138.868 CPU sec, 4.475 real sec
sorting block 73, #reads = 1074539 mem = 536879740 peak = 1068630016
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 282348, 29, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 281, 599)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1447)
[M::mem_pestat] mean and std.dev: (361.30, 330.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1871)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 232, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 692)
[M::mem_pestat] mean and std.dev: (256.88, 126.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 870)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (504, 861, 2179)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5529)
[M::mem_pestat] mean and std.dev: (1287.14, 1208.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7204)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 363, 1645)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4573)
[M::mem_pestat] mean and std.dev: (746.47, 677.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6037)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698372 sequences (100000262 bp) in 2.655 CPU sec, 3.079 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 282553, 31, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 294, 636)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1460)
[M::mem_pestat] mean and std.dev: (388.26, 275.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1872)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 232, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 695)
[M::mem_pestat] mean and std.dev: (257.38, 126.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 874)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 293, 795)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1999)
[M::mem_pestat] mean and std.dev: (481.90, 443.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2601)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 416, 712)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1730)
[M::mem_pestat] mean and std.dev: (418.33, 262.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2239)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697896 sequences (100000108 bp) in 2.231 CPU sec, 2.239 real sec...
[M::mem_process_seqs] Processed 698868 reads in 197.418 CPU sec, 6.450 real sec
sorting block 74, #reads = 1075230 mem = 536882931 peak = 1068630016
[M::mem_process_seqs] Processed 698458 reads in 137.658 CPU sec, 4.521 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 282321, 22, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 407, 1317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3527)
[M::mem_pestat] mean and std.dev: (751.84, 662.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4632)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 233, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 693)
[M::mem_pestat] mean and std.dev: (257.68, 126.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 871)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 1191, 3243)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9285)
[M::mem_pestat] mean and std.dev: (1970.86, 2532.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12306)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 306, 717)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1791)
[M::mem_pestat] mean and std.dev: (400.50, 337.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2328)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 75, #reads = 1074519 mem = 536880300 peak = 1068769280
[M::process] read 697740 sequences (100000122 bp) in 2.631 CPU sec, 3.020 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 281752, 26, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (412, 834, 963)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2065)
[M::mem_pestat] mean and std.dev: (806.84, 496.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2794)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 234, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 696)
[M::mem_pestat] mean and std.dev: (258.97, 126.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 875)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (516, 1242, 1661)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3951)
[M::mem_pestat] mean and std.dev: (1121.75, 691.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5096)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (245, 350, 835)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2015)
[M::mem_pestat] mean and std.dev: (562.08, 500.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2605)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697342 sequences (100000240 bp) in 2.191 CPU sec, 2.194 real sec...
[M::mem_process_seqs] Processed 698372 reads in 196.312 CPU sec, 6.454 real sec
[M::mem_process_seqs] Processed 697896 reads in 140.006 CPU sec, 4.516 real sec
sorting block 76, #reads = 1073944 mem = 536880017 peak = 1068769280
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 282445, 23, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (146, 313, 731)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1901)
[M::mem_pestat] mean and std.dev: (367.53, 251.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2486)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 234, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 694)
[M::mem_pestat] mean and std.dev: (258.78, 126.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 872)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (67, 340, 1292)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3742)
[M::mem_pestat] mean and std.dev: (579.19, 779.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4967)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 393, 766)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1968)
[M::mem_pestat] mean and std.dev: (488.00, 405.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2569)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696812 sequences (100000286 bp) in 2.718 CPU sec, 3.077 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 282274, 22, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 238, 599)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1451)
[M::mem_pestat] mean and std.dev: (326.95, 313.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1877)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 236, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 700)
[M::mem_pestat] mean and std.dev: (259.62, 126.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 880)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (276, 486, 614)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1290)
[M::mem_pestat] mean and std.dev: (384.39, 196.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1628)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (240, 359, 936)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2328)
[M::mem_pestat] mean and std.dev: (601.68, 442.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3024)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696178 sequences (100000123 bp) in 2.203 CPU sec, 2.213 real sec...
[M::mem_process_seqs] Processed 697740 reads in 200.209 CPU sec, 6.538 real sec
[M::mem_process_seqs] Processed 697342 reads in 141.338 CPU sec, 4.543 real sec
sorting block 77, #reads = 1072498 mem = 536879260 peak = 1068769280
[M::process] read 696302 sequences (100000072 bp) in 2.554 CPU sec, 3.042 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 281683, 38, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 406, 1878)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5270)
[M::mem_pestat] mean and std.dev: (828.95, 932.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6966)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 239, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 705)
[M::mem_pestat] mean and std.dev: (262.23, 127.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 886)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (44, 611, 957)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2783)
[M::mem_pestat] mean and std.dev: (617.50, 559.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3696)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (319, 810, 2731)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7555)
[M::mem_pestat] mean and std.dev: (1294.72, 1432.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9967)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695756 sequences (100000173 bp) in 2.188 CPU sec, 2.190 real sec...
[M::mem_process_seqs] Processed 696178 reads in 115.068 CPU sec, 3.703 real sec
sorting block 78, #reads = 1072213 mem = 536883736 peak = 1068769280
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 282055, 23, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 569, 1606)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4390)
[M::mem_pestat] mean and std.dev: (852.93, 944.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5782)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 237, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 701)
[M::mem_pestat] mean and std.dev: (260.84, 126.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 881)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (77, 425, 1679)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4883)
[M::mem_pestat] mean and std.dev: (482.78, 563.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6485)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 328, 730)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1848)
[M::mem_pestat] mean and std.dev: (389.71, 311.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2407)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 281702, 33, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 621, 2101)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5955)
[M::mem_pestat] mean and std.dev: (1043.29, 1159.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7882)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 239, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 705)
[M::mem_pestat] mean and std.dev: (262.58, 127.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 886)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (355, 1046, 1793)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4669)
[M::mem_pestat] mean and std.dev: (1085.79, 845.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6107)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (262, 507, 986)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2434)
[M::mem_pestat] mean and std.dev: (634.53, 580.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3158)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696812 reads in 306.414 CPU sec, 9.965 real sec
[M::process] read 695580 sequences (100000169 bp) in 2.327 CPU sec, 2.443 real sec...
[M::mem_process_seqs] Processed 696302 reads in 170.777 CPU sec, 5.782 real sec
sorting block 79, #reads = 1072559 mem = 536877278 peak = 1068769280
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 281705, 33, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 310, 576)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1330)
[M::mem_pestat] mean and std.dev: (408.18, 331.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1736)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 239, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 703)
[M::mem_pestat] mean and std.dev: (262.79, 126.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 883)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (120, 592, 1776)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5088)
[M::mem_pestat] mean and std.dev: (860.52, 860.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6744)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 309, 512)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1126)
[M::mem_pestat] mean and std.dev: (339.77, 174.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1433)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695592 sequences (100000209 bp) in 2.815 CPU sec, 3.155 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 281628, 25, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 379, 1323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3627)
[M::mem_pestat] mean and std.dev: (753.85, 755.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4779)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 241, 345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 709)
[M::mem_pestat] mean and std.dev: (263.60, 126.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 891)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 577, 2222)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6240)
[M::mem_pestat] mean and std.dev: (1265.40, 1271.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8249)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (322, 756, 1471)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3769)
[M::mem_pestat] mean and std.dev: (958.95, 722.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4918)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695506 sequences (100000234 bp) in 2.137 CPU sec, 2.160 real sec...
[M::mem_process_seqs] Processed 695756 reads in 199.340 CPU sec, 6.639 real sec
sorting block 80, #reads = 1071519 mem = 536879835 peak = 1068769280
[M::mem_process_seqs] Processed 695580 reads in 142.858 CPU sec, 4.618 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 281117, 13, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 685, 1082)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2828)
[M::mem_pestat] mean and std.dev: (626.81, 517.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3701)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 240, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 706)
[M::mem_pestat] mean and std.dev: (263.27, 127.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 887)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (134, 702, 1184)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3284)
[M::mem_pestat] mean and std.dev: (942.23, 1044.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5119)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 293, 628)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1432)
[M::mem_pestat] mean and std.dev: (474.17, 393.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2049)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695610 sequences (100000127 bp) in 2.745 CPU sec, 3.099 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 280899, 39, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (292, 753, 2302)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6322)
[M::mem_pestat] mean and std.dev: (1141.28, 1060.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8332)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 241, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 703)
[M::mem_pestat] mean and std.dev: (263.25, 126.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 883)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (365, 963, 2978)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8204)
[M::mem_pestat] mean and std.dev: (1298.15, 1616.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10817)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (253, 445, 957)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2365)
[M::mem_pestat] mean and std.dev: (624.94, 541.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3069)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695628 sequences (100000159 bp) in 2.239 CPU sec, 2.240 real sec...
[M::mem_process_seqs] Processed 695592 reads in 199.380 CPU sec, 6.410 real sec
sorting block 81, #reads = 1072008 mem = 536876710 peak = 1079791616
[M::mem_process_seqs] Processed 695506 reads in 144.905 CPU sec, 4.655 real sec
sorting block 82, #reads = 1070429 mem = 536880931 peak = 1083273216
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 281049, 35, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (247, 477, 1047)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2647)
[M::mem_pestat] mean and std.dev: (531.06, 483.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3447)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 239, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 700)
[M::mem_pestat] mean and std.dev: (262.22, 125.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 879)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (114, 469, 3640)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10692)
[M::mem_pestat] mean and std.dev: (1722.34, 2028.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14218)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 490, 1121)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2975)
[M::mem_pestat] mean and std.dev: (772.32, 709.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3902)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695618 sequences (100000183 bp) in 2.614 CPU sec, 3.143 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 281717, 30, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 326, 1419)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3841)
[M::mem_pestat] mean and std.dev: (810.96, 944.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5052)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 240, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 703)
[M::mem_pestat] mean and std.dev: (262.66, 125.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 883)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (465, 700, 1798)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4464)
[M::mem_pestat] mean and std.dev: (958.17, 798.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5797)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 272, 548)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1240)
[M::mem_pestat] mean and std.dev: (404.20, 266.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1586)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695558 sequences (100000068 bp) in 2.213 CPU sec, 2.218 real sec...
[M::mem_process_seqs] Processed 695610 reads in 203.690 CPU sec, 6.676 real sec
[M::mem_process_seqs] Processed 695628 reads in 144.754 CPU sec, 4.792 real sec
sorting block 83, #reads = 1068871 mem = 536879543 peak = 1083273216
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 281290, 41, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 280, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 723)
[M::mem_pestat] mean and std.dev: (249.91, 112.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 901)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 239, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 697)
[M::mem_pestat] mean and std.dev: (261.36, 124.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 875)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (311, 522, 1527)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3959)
[M::mem_pestat] mean and std.dev: (781.97, 718.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5175)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (313, 437, 589)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1141)
[M::mem_pestat] mean and std.dev: (400.98, 185.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1417)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701494 sequences (100000134 bp) in 2.759 CPU sec, 3.142 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 280916, 36, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 418, 711)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1793)
[M::mem_pestat] mean and std.dev: (483.60, 403.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2334)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 240, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 703)
[M::mem_pestat] mean and std.dev: (262.76, 125.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 883)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 373, 879)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2335)
[M::mem_pestat] mean and std.dev: (547.76, 494.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3063)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (239, 382, 1145)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2957)
[M::mem_pestat] mean and std.dev: (644.31, 644.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3863)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706884 sequences (100000201 bp) in 2.330 CPU sec, 2.331 real sec...
[M::mem_process_seqs] Processed 695618 reads in 207.185 CPU sec, 6.746 real sec
[M::mem_process_seqs] Processed 695558 reads in 148.015 CPU sec, 4.741 real sec
sorting block 84, #reads = 1069582 mem = 536878659 peak = 1083273216
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 283203, 14, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 255, 507)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1179)
[M::mem_pestat] mean and std.dev: (294.79, 218.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1515)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 223, 323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 661)
[M::mem_pestat] mean and std.dev: (247.96, 120.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 830)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (92, 1089, 1591)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4589)
[M::mem_pestat] mean and std.dev: (772.25, 679.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6088)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 280, 1044)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2830)
[M::mem_pestat] mean and std.dev: (315.86, 261.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3723)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705244 sequences (100000262 bp) in 2.700 CPU sec, 3.109 real sec...
[M::process] read 704788 sequences (100000043 bp) in 2.242 CPU sec, 2.251 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 285162, 23, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (225, 523, 2075)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5775)
[M::mem_pestat] mean and std.dev: (1091.56, 1199.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7625)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 209, 300)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 606)
[M::mem_pestat] mean and std.dev: (232.51, 111.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 759)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (403, 836, 2124)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5566)
[M::mem_pestat] mean and std.dev: (1155.41, 1184.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7287)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 309, 591)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1443)
[M::mem_pestat] mean and std.dev: (398.71, 313.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1869)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701494 reads in 230.256 CPU sec, 7.540 real sec
sorting block 85, #reads = 1067610 mem = 536878856 peak = 1083273216
[M::mem_process_seqs] Processed 706884 reads in 157.912 CPU sec, 5.077 real sec
sorting block 86, #reads = 1069070 mem = 536880450 peak = 1118621696
[M::process] read 704802 sequences (100000114 bp) in 2.706 CPU sec, 3.154 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 284279, 14, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (140, 245, 435)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1025)
[M::mem_pestat] mean and std.dev: (272.00, 196.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1320)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 213, 308)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 626)
[M::mem_pestat] mean and std.dev: (237.86, 115.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 785)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (697, 929, 1507)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3127)
[M::mem_pestat] mean and std.dev: (1008.57, 661.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3937)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 211, 932)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2488)
[M::mem_pestat] mean and std.dev: (540.18, 578.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3266)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703164 sequences (100000015 bp) in 2.221 CPU sec, 2.241 real sec...
[M::mem_process_seqs] Processed 704788 reads in 127.464 CPU sec, 4.065 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 284885, 21, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 374, 944)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2512)
[M::mem_pestat] mean and std.dev: (447.74, 425.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3296)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 212, 307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 623)
[M::mem_pestat] mean and std.dev: (236.92, 115.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 781)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 306, 1012)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2666)
[M::mem_pestat] mean and std.dev: (476.14, 425.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3493)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (254, 352, 750)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1742)
[M::mem_pestat] mean and std.dev: (454.42, 311.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2238)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 285429, 13, 24)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (238, 493, 2081)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5767)
[M::mem_pestat] mean and std.dev: (957.13, 1001.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7610)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 213, 308)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 626)
[M::mem_pestat] mean and std.dev: (237.93, 115.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 785)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (419, 1597, 3352)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9218)
[M::mem_pestat] mean and std.dev: (1990.00, 2343.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12151)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 310, 513)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1181)
[M::mem_pestat] mean and std.dev: (353.22, 217.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1515)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702082 sequences (100000035 bp) in 2.429 CPU sec, 2.551 real sec...
[M::mem_process_seqs] Processed 705244 reads in 338.337 CPU sec, 10.893 real sec
sorting block 87, #reads = 1073752 mem = 536879648 peak = 1118621696
[M::mem_process_seqs] Processed 704802 reads in 183.055 CPU sec, 6.080 real sec
sorting block 88, #reads = 1073222 mem = 536879102 peak = 1118621696
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 284183, 21, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (358, 589, 2245)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6019)
[M::mem_pestat] mean and std.dev: (1385.88, 1676.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8092)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 218, 316)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 646)
[M::mem_pestat] mean and std.dev: (243.27, 118.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 811)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 547, 1376)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3718)
[M::mem_pestat] mean and std.dev: (679.67, 576.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4889)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 293, 805)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2043)
[M::mem_pestat] mean and std.dev: (530.62, 491.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2662)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701638 sequences (100000216 bp) in 2.712 CPU sec, 2.972 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 284264, 23, 23)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (230, 380, 724)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1712)
[M::mem_pestat] mean and std.dev: (444.12, 367.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2206)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 221, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 660)
[M::mem_pestat] mean and std.dev: (247.05, 121.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 829)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (140, 745, 1888)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5384)
[M::mem_pestat] mean and std.dev: (1150.26, 1115.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7132)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 335, 1064)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2824)
[M::mem_pestat] mean and std.dev: (400.15, 323.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3704)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701290 sequences (100000130 bp) in 2.228 CPU sec, 2.239 real sec...
[M::mem_process_seqs] Processed 703164 reads in 209.956 CPU sec, 6.948 real sec
[M::mem_process_seqs] Processed 702082 reads in 145.564 CPU sec, 4.677 real sec
sorting block 89, #reads = 1073789 mem = 536886051 peak = 1118621696
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 284196, 23, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (228, 347, 1257)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3315)
[M::mem_pestat] mean and std.dev: (724.70, 722.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4344)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 222, 323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 663)
[M::mem_pestat] mean and std.dev: (247.90, 121.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 833)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (553, 636, 1390)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3064)
[M::mem_pestat] mean and std.dev: (719.60, 552.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3901)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 275, 872)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2218)
[M::mem_pestat] mean and std.dev: (544.03, 603.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2959)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700752 sequences (100000220 bp) in 2.811 CPU sec, 3.149 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 283920, 14, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 432, 1333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3615)
[M::mem_pestat] mean and std.dev: (739.44, 651.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4756)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 223, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 670)
[M::mem_pestat] mean and std.dev: (250.12, 123.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 842)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 765, 1733)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4805)
[M::mem_pestat] mean and std.dev: (1066.69, 1323.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6362)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 440, 809)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2107)
[M::mem_pestat] mean and std.dev: (550.04, 445.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2756)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700388 sequences (100000184 bp) in 2.285 CPU sec, 2.303 real sec...
[M::mem_process_seqs] Processed 701638 reads in 205.808 CPU sec, 6.765 real sec
[M::mem_process_seqs] Processed 701290 reads in 146.392 CPU sec, 4.769 real sec
sorting block 90, #reads = 1073952 mem = 536891184 peak = 1118621696
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 283309, 17, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (537, 1264, 2331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5919)
[M::mem_pestat] mean and std.dev: (1096.25, 692.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7713)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 225, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 674)
[M::mem_pestat] mean and std.dev: (251.07, 124.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 847)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (420, 1398, 3963)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 11049)
[M::mem_pestat] mean and std.dev: (1814.59, 1869.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14592)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 402, 1321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3585)
[M::mem_pestat] mean and std.dev: (606.81, 646.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4717)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700238 sequences (100000025 bp) in 2.604 CPU sec, 3.019 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 283905, 22, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 281, 1621)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4553)
[M::mem_pestat] mean and std.dev: (627.71, 793.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6019)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 226, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 680)
[M::mem_pestat] mean and std.dev: (252.58, 125.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 855)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 420, 2693)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7685)
[M::mem_pestat] mean and std.dev: (1927.23, 2582.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12258)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 336, 1224)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3214)
[M::mem_pestat] mean and std.dev: (505.05, 470.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4209)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699826 sequences (100000019 bp) in 2.308 CPU sec, 2.323 real sec...
[M::mem_process_seqs] Processed 700752 reads in 203.708 CPU sec, 6.591 real sec
sorting block 91, #reads = 1074661 mem = 536881802 peak = 1118621696
[M::mem_process_seqs] Processed 700388 reads in 151.051 CPU sec, 4.875 real sec
sorting block 92, #reads = 1073887 mem = 536883532 peak = 1118621696
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 282676, 29, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (235, 448, 868)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2134)
[M::mem_pestat] mean and std.dev: (544.10, 429.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2767)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 226, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 680)
[M::mem_pestat] mean and std.dev: (252.77, 124.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 855)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (452, 798, 1505)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3611)
[M::mem_pestat] mean and std.dev: (982.39, 864.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4664)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 378, 815)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2029)
[M::mem_pestat] mean and std.dev: (554.06, 489.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2636)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699700 sequences (100000215 bp) in 2.596 CPU sec, 2.642 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 283240, 39, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 304, 1979)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5557)
[M::mem_pestat] mean and std.dev: (1186.33, 1678.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7900)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 227, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 681)
[M::mem_pestat] mean and std.dev: (253.36, 125.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 856)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (284, 1161, 2094)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5714)
[M::mem_pestat] mean and std.dev: (904.64, 808.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7524)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 331, 647)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1547)
[M::mem_pestat] mean and std.dev: (405.74, 334.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1997)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699540 sequences (100000215 bp) in 2.240 CPU sec, 2.243 real sec...
[M::mem_process_seqs] Processed 700238 reads in 193.877 CPU sec, 6.149 real sec
[M::mem_process_seqs] Processed 699826 reads in 136.680 CPU sec, 4.438 real sec
sorting block 93, #reads = 1071916 mem = 536881449 peak = 1118621696
[M::process] read 699824 sequences (100000221 bp) in 2.615 CPU sec, 2.683 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 282752, 18, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 437, 1184)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3240)
[M::mem_pestat] mean and std.dev: (593.76, 600.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4268)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 229, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 693)
[M::mem_pestat] mean and std.dev: (255.91, 127.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 872)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 605, 1868)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5200)
[M::mem_pestat] mean and std.dev: (994.06, 978.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6866)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (352, 847, 1136)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2704)
[M::mem_pestat] mean and std.dev: (822.66, 604.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3488)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699700 reads in 119.255 CPU sec, 3.949 real sec
sorting block 94, #reads = 1071198 mem = 536883440 peak = 1118621696
[M::process] read 698724 sequences (100000210 bp) in 2.525 CPU sec, 2.713 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 283005, 16, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (138, 369, 1014)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2766)
[M::mem_pestat] mean and std.dev: (496.02, 596.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3642)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 229, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 688)
[M::mem_pestat] mean and std.dev: (255.92, 127.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 865)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (366, 1375, 1698)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4362)
[M::mem_pestat] mean and std.dev: (1030.25, 668.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5694)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (269, 399, 732)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1658)
[M::mem_pestat] mean and std.dev: (468.63, 340.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2121)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698446 sequences (100000236 bp) in 2.613 CPU sec, 2.625 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 282957, 38, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 267, 638)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1576)
[M::mem_pestat] mean and std.dev: (443.22, 398.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2045)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 228, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 687)
[M::mem_pestat] mean and std.dev: (254.67, 126.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 864)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (507, 636, 896)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1674)
[M::mem_pestat] mean and std.dev: (718.22, 370.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2199)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 542, 923)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2315)
[M::mem_pestat] mean and std.dev: (568.00, 489.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3011)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699540 reads in 231.024 CPU sec, 7.390 real sec
[M::mem_process_seqs] Processed 699824 reads in 256.092 CPU sec, 8.408 real sec
sorting block 95, #reads = 1071056 mem = 536879745 peak = 1118621696
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 281920, 17, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 329, 938)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2444)
[M::mem_pestat] mean and std.dev: (498.79, 506.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3197)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 230, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 688)
[M::mem_pestat] mean and std.dev: (256.12, 126.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 865)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (95, 793, 1396)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3998)
[M::mem_pestat] mean and std.dev: (740.44, 680.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5299)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (144, 373, 791)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2085)
[M::mem_pestat] mean and std.dev: (504.06, 431.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2732)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697978 sequences (100000240 bp) in 3.542 CPU sec, 3.774 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 282007, 30, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (250, 377, 1304)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3412)
[M::mem_pestat] mean and std.dev: (536.69, 430.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4466)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 230, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 683)
[M::mem_pestat] mean and std.dev: (255.56, 124.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 858)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (459, 864, 1408)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3306)
[M::mem_pestat] mean and std.dev: (938.10, 681.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4255)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (246, 441, 1165)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3003)
[M::mem_pestat] mean and std.dev: (659.33, 604.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3922)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697656 sequences (100000169 bp) in 2.614 CPU sec, 2.619 real sec...
[M::mem_process_seqs] Processed 698724 reads in 223.843 CPU sec, 7.314 real sec
[M::mem_process_seqs] Processed 698446 reads in 157.852 CPU sec, 5.124 real sec
sorting block 96, #reads = 1069654 mem = 536878969 peak = 1118621696
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 281969, 36, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 364, 971)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2563)
[M::mem_pestat] mean and std.dev: (533.35, 426.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3359)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 231, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 687)
[M::mem_pestat] mean and std.dev: (257.08, 126.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 863)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (356, 794, 1612)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4124)
[M::mem_pestat] mean and std.dev: (815.29, 606.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5380)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 263, 621)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1503)
[M::mem_pestat] mean and std.dev: (352.53, 280.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1944)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697038 sequences (100000267 bp) in 2.970 CPU sec, 3.226 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 281674, 40, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 381, 749)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1869)
[M::mem_pestat] mean and std.dev: (423.40, 359.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2429)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 232, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 693)
[M::mem_pestat] mean and std.dev: (257.86, 126.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 871)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (307, 522, 1118)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2740)
[M::mem_pestat] mean and std.dev: (601.36, 442.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3551)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (243, 454, 1383)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3663)
[M::mem_pestat] mean and std.dev: (810.85, 816.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4803)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697034 sequences (100000167 bp) in 2.187 CPU sec, 2.197 real sec...
[M::mem_process_seqs] Processed 697978 reads in 213.340 CPU sec, 6.911 real sec
sorting block 97, #reads = 1067834 mem = 536887179 peak = 1118621696
[M::mem_process_seqs] Processed 697656 reads in 146.743 CPU sec, 4.664 real sec
sorting block 98, #reads = 1066939 mem = 536882647 peak = 1118621696
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 281332, 30, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 269, 914)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2374)
[M::mem_pestat] mean and std.dev: (509.23, 514.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3104)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 234, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 691)
[M::mem_pestat] mean and std.dev: (258.67, 126.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 868)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (417, 1075, 1731)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4359)
[M::mem_pestat] mean and std.dev: (1210.27, 1067.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5673)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (237, 573, 1211)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3159)
[M::mem_pestat] mean and std.dev: (774.08, 725.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4133)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697428 sequences (100000038 bp) in 2.624 CPU sec, 2.699 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 281427, 33, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (226, 525, 1343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3577)
[M::mem_pestat] mean and std.dev: (799.17, 691.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4694)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 233, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 691)
[M::mem_pestat] mean and std.dev: (258.20, 125.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 868)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (137, 666, 1182)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3272)
[M::mem_pestat] mean and std.dev: (816.91, 891.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4384)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 271, 667)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1661)
[M::mem_pestat] mean and std.dev: (350.91, 268.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2158)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697886 sequences (100000020 bp) in 2.260 CPU sec, 2.258 real sec...
[M::mem_process_seqs] Processed 697038 reads in 200.737 CPU sec, 6.391 real sec
[M::mem_process_seqs] Processed 697034 reads in 146.458 CPU sec, 4.724 real sec
sorting block 99, #reads = 1069168 mem = 536881500 peak = 1118621696
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 281633, 23, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 436, 1701)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4735)
[M::mem_pestat] mean and std.dev: (740.80, 674.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6252)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 232, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 690)
[M::mem_pestat] mean and std.dev: (257.52, 125.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 867)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (448, 998, 1400)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3304)
[M::mem_pestat] mean and std.dev: (778.95, 481.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4256)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 326, 551)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1229)
[M::mem_pestat] mean and std.dev: (333.78, 175.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1568)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697618 sequences (100000044 bp) in 2.729 CPU sec, 3.140 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 281712, 27, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 340, 639)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1577)
[M::mem_pestat] mean and std.dev: (375.59, 267.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2046)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 231, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 684)
[M::mem_pestat] mean and std.dev: (256.28, 124.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 859)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 435, 757)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1853)
[M::mem_pestat] mean and std.dev: (446.54, 341.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2401)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 309, 1406)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3860)
[M::mem_pestat] mean and std.dev: (647.59, 719.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5087)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698048 sequences (100000197 bp) in 2.327 CPU sec, 2.374 real sec...
[M::mem_process_seqs] Processed 697428 reads in 214.880 CPU sec, 6.957 real sec
[M::mem_process_seqs] Processed 697886 reads in 152.010 CPU sec, 4.847 real sec
sorting block 100, #reads = 1068904 mem = 536880059 peak = 1118621696
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 281406, 24, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 547, 1340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3572)
[M::mem_pestat] mean and std.dev: (741.66, 575.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4688)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 232, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 684)
[M::mem_pestat] mean and std.dev: (256.75, 124.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 859)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 711, 2143)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5967)
[M::mem_pestat] mean and std.dev: (1098.88, 1229.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7879)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (247, 843, 1715)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4651)
[M::mem_pestat] mean and std.dev: (1102.71, 1114.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6119)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697378 sequences (100000031 bp) in 2.650 CPU sec, 2.793 real sec...
[M::process] read 696964 sequences (100000085 bp) in 2.210 CPU sec, 2.219 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 281620, 33, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (240, 536, 1658)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4494)
[M::mem_pestat] mean and std.dev: (895.16, 1017.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5912)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 230, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 683)
[M::mem_pestat] mean and std.dev: (255.71, 124.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 858)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (856, 1884, 3755)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9553)
[M::mem_pestat] mean and std.dev: (2360.24, 2050.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12452)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (255, 750, 2538)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7104)
[M::mem_pestat] mean and std.dev: (1000.94, 1197.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9387)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697618 reads in 208.004 CPU sec, 6.725 real sec
sorting block 101, #reads = 1068528 mem = 536884524 peak = 1118621696
[M::mem_process_seqs] Processed 698048 reads in 140.763 CPU sec, 4.629 real sec
sorting block 102, #reads = 1067876 mem = 536884204 peak = 1118621696
[M::process] read 697026 sequences (100000145 bp) in 2.773 CPU sec, 2.817 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 281322, 24, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 337, 935)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2499)
[M::mem_pestat] mean and std.dev: (482.93, 535.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3281)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 231, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 681)
[M::mem_pestat] mean and std.dev: (255.94, 124.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 855)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (340, 516, 1565)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4015)
[M::mem_pestat] mean and std.dev: (840.87, 688.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5240)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 375, 709)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1715)
[M::mem_pestat] mean and std.dev: (399.26, 279.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2218)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696822 sequences (100000131 bp) in 2.231 CPU sec, 2.236 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 281722, 17, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 452, 618)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1494)
[M::mem_pestat] mean and std.dev: (465.98, 350.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1932)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 233, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 688)
[M::mem_pestat] mean and std.dev: (257.83, 125.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 864)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (97, 834, 1805)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5221)
[M::mem_pestat] mean and std.dev: (1042.06, 1080.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6929)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 302, 688)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1702)
[M::mem_pestat] mean and std.dev: (475.89, 395.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2209)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697378 reads in 198.533 CPU sec, 6.429 real sec
[M::mem_process_seqs] Processed 696964 reads in 223.083 CPU sec, 7.370 real sec
sorting block 103, #reads = 1066999 mem = 536880413 peak = 1118621696
[M::process] read 697472 sequences (100000145 bp) in 2.278 CPU sec, 2.337 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 281430, 31, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 415, 1074)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2886)
[M::mem_pestat] mean and std.dev: (593.32, 568.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3792)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 234, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 688)
[M::mem_pestat] mean and std.dev: (257.95, 124.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 864)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (367, 835, 2544)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6898)
[M::mem_pestat] mean and std.dev: (1312.33, 1317.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9075)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (289, 596, 1111)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2755)
[M::mem_pestat] mean and std.dev: (738.08, 615.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3577)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702586 sequences (100000054 bp) in 1.760 CPU sec, 1.756 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 281177, 23, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (287, 526, 1315)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3371)
[M::mem_pestat] mean and std.dev: (605.27, 498.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4399)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 233, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 688)
[M::mem_pestat] mean and std.dev: (258.07, 125.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 864)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (272, 868, 1512)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3992)
[M::mem_pestat] mean and std.dev: (935.00, 782.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5232)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 317, 684)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1648)
[M::mem_pestat] mean and std.dev: (377.78, 265.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2130)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696822 reads in 188.609 CPU sec, 6.127 real sec
sorting block 104, #reads = 1068503 mem = 536880473 peak = 1118621696
[M::mem_process_seqs] Processed 697026 reads in 216.367 CPU sec, 7.028 real sec
[M::process] read 707954 sequences (100000085 bp) in 2.354 CPU sec, 2.407 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 282992, 22, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (305, 456, 1043)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2519)
[M::mem_pestat] mean and std.dev: (530.15, 368.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3257)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 219, 317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 647)
[M::mem_pestat] mean and std.dev: (244.27, 118.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 812)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (226, 630, 1301)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3451)
[M::mem_pestat] mean and std.dev: (796.32, 644.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4526)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (249, 319, 787)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1863)
[M::mem_pestat] mean and std.dev: (492.44, 424.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2401)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 707218 sequences (100000024 bp) in 1.740 CPU sec, 1.738 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 281772, 19, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 419, 2090)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5894)
[M::mem_pestat] mean and std.dev: (1209.89, 1364.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7796)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 233, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 691)
[M::mem_pestat] mean and std.dev: (257.91, 125.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 868)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (308, 676, 1183)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2933)
[M::mem_pestat] mean and std.dev: (713.18, 599.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3808)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (276, 694, 1392)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3624)
[M::mem_pestat] mean and std.dev: (915.98, 836.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4740)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702586 reads in 203.814 CPU sec, 6.470 real sec
sorting block 105, #reads = 1065277 mem = 536881932 peak = 1118621696
[M::mem_process_seqs] Processed 697472 reads in 231.912 CPU sec, 7.381 real sec
sorting block 106, #reads = 1064639 mem = 536878063 peak = 1118621696
[M::process] read 706304 sequences (100000116 bp) in 2.776 CPU sec, 2.820 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 285447, 26, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (226, 327, 808)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1972)
[M::mem_pestat] mean and std.dev: (431.60, 353.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2554)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 209, 300)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 608)
[M::mem_pestat] mean and std.dev: (232.00, 111.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 762)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (87, 652, 1067)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3027)
[M::mem_pestat] mean and std.dev: (606.50, 670.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4007)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 349, 1329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3535)
[M::mem_pestat] mean and std.dev: (631.67, 654.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4638)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706346 sequences (100000241 bp) in 2.680 CPU sec, 2.690 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (21, 285342, 23, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 245, 530)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1266)
[M::mem_pestat] mean and std.dev: (297.32, 233.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1634)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 206, 296)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 598)
[M::mem_pestat] mean and std.dev: (229.71, 109.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 749)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (411, 1080, 2055)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5343)
[M::mem_pestat] mean and std.dev: (1085.38, 872.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6987)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 356, 1457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3977)
[M::mem_pestat] mean and std.dev: (701.78, 762.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5237)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 707218 reads in 217.054 CPU sec, 6.853 real sec
[M::mem_process_seqs] Processed 707954 reads in 243.833 CPU sec, 7.717 real sec
sorting block 107, #reads = 1067666 mem = 536879807 peak = 1118621696
[M::process] read 705604 sequences (100000150 bp) in 2.899 CPU sec, 2.938 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 284707, 24, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (134, 266, 382)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 878)
[M::mem_pestat] mean and std.dev: (243.41, 154.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1126)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 210, 302)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 612)
[M::mem_pestat] mean and std.dev: (233.65, 112.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 767)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 1318, 1797)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4961)
[M::mem_pestat] mean and std.dev: (1085.96, 963.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6543)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 322, 674)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1680)
[M::mem_pestat] mean and std.dev: (312.96, 222.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2183)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704280 sequences (100000107 bp) in 2.329 CPU sec, 2.327 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 285387, 24, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 491, 1243)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3343)
[M::mem_pestat] mean and std.dev: (804.07, 922.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4494)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 210, 303)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 615)
[M::mem_pestat] mean and std.dev: (234.15, 112.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 771)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 712, 2217)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6343)
[M::mem_pestat] mean and std.dev: (1180.79, 1151.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8406)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 240, 622)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1514)
[M::mem_pestat] mean and std.dev: (374.69, 308.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1960)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 706346 reads in 224.564 CPU sec, 7.118 real sec
sorting block 108, #reads = 1065555 mem = 536878144 peak = 1118621696
[M::mem_process_seqs] Processed 706304 reads in 257.317 CPU sec, 8.191 real sec
[M::process] read 704016 sequences (100000074 bp) in 2.834 CPU sec, 2.877 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 284460, 36, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 335, 783)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1959)
[M::mem_pestat] mean and std.dev: (557.84, 495.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2547)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 216, 312)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 636)
[M::mem_pestat] mean and std.dev: (240.13, 115.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 798)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (265, 372, 1470)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3880)
[M::mem_pestat] mean and std.dev: (834.72, 894.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5085)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 438, 1914)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5304)
[M::mem_pestat] mean and std.dev: (704.31, 713.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6999)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703174 sequences (100000085 bp) in 2.370 CPU sec, 2.369 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 285161, 26, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 235, 970)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2594)
[M::mem_pestat] mean and std.dev: (532.11, 515.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3406)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 213, 307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 625)
[M::mem_pestat] mean and std.dev: (236.91, 114.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 784)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (369, 985, 1836)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4770)
[M::mem_pestat] mean and std.dev: (1229.73, 957.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6237)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (231, 351, 1333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3537)
[M::mem_pestat] mean and std.dev: (672.88, 641.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4639)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704280 reads in 229.310 CPU sec, 7.269 real sec
sorting block 109, #reads = 1067990 mem = 536886165 peak = 1118621696
[M::mem_process_seqs] Processed 705604 reads in 261.692 CPU sec, 8.566 real sec
sorting block 110, #reads = 1066234 mem = 536881627 peak = 1118621696
[M::process] read 702470 sequences (100000301 bp) in 2.565 CPU sec, 2.667 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 284710, 26, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 273, 643)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1591)
[M::mem_pestat] mean and std.dev: (282.00, 171.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2065)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 216, 312)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 636)
[M::mem_pestat] mean and std.dev: (240.50, 116.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 798)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (336, 917, 1790)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4698)
[M::mem_pestat] mean and std.dev: (697.70, 471.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6152)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 335, 586)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1310)
[M::mem_pestat] mean and std.dev: (365.42, 226.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1672)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701816 sequences (100000255 bp) in 2.329 CPU sec, 2.339 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 283768, 15, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (227, 330, 594)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1328)
[M::mem_pestat] mean and std.dev: (385.25, 294.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1695)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 217, 315)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 643)
[M::mem_pestat] mean and std.dev: (242.72, 118.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 807)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (548, 803, 2086)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5162)
[M::mem_pestat] mean and std.dev: (1040.14, 808.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6700)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 355, 1049)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2703)
[M::mem_pestat] mean and std.dev: (724.65, 692.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3530)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 284401, 23, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 374, 716)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1734)
[M::mem_pestat] mean and std.dev: (499.94, 408.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2243)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 220, 319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 653)
[M::mem_pestat] mean and std.dev: (245.10, 119.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 820)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (247, 499, 2547)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7147)
[M::mem_pestat] mean and std.dev: (1046.90, 1090.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9447)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 351, 1341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3637)
[M::mem_pestat] mean and std.dev: (712.21, 938.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4785)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704016 reads in 327.610 CPU sec, 10.751 real sec
[M::mem_process_seqs] Processed 703174 reads in 259.018 CPU sec, 8.365 real sec
[M::mem_process_seqs] Processed 702470 reads in 287.421 CPU sec, 9.304 real sec
sorting block 111, #reads = 1066754 mem = 536877564 peak = 1118621696
[M::process] read 701392 sequences (100000058 bp) in 2.762 CPU sec, 3.030 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 284453, 25, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 336, 757)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1843)
[M::mem_pestat] mean and std.dev: (460.23, 431.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2386)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 222, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 657)
[M::mem_pestat] mean and std.dev: (246.87, 120.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 825)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (359, 544, 1037)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2393)
[M::mem_pestat] mean and std.dev: (527.33, 325.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3071)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (235, 365, 631)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1423)
[M::mem_pestat] mean and std.dev: (434.12, 280.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1819)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700872 sequences (100000231 bp) in 2.779 CPU sec, 3.333 real sec...
sorting block 112, #reads = 1068529 mem = 536880664 peak = 1123512320
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 283214, 31, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 464, 1179)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3097)
[M::mem_pestat] mean and std.dev: (595.36, 507.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4056)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 223, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 664)
[M::mem_pestat] mean and std.dev: (248.29, 121.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 834)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (322, 649, 1334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3358)
[M::mem_pestat] mean and std.dev: (861.03, 788.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4370)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 353, 629)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1451)
[M::mem_pestat] mean and std.dev: (405.23, 252.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1862)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701816 reads in 224.842 CPU sec, 7.453 real sec
[M::mem_process_seqs] Processed 701392 reads in 161.492 CPU sec, 5.402 real sec
[M::process] read 700762 sequences (100000270 bp) in 2.581 CPU sec, 2.748 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 283724, 21, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 297, 581)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1345)
[M::mem_pestat] mean and std.dev: (339.51, 213.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1727)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 224, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 667)
[M::mem_pestat] mean and std.dev: (249.86, 122.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 838)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (274, 1107, 1208)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3076)
[M::mem_pestat] mean and std.dev: (815.60, 651.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4010)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 829, 1424)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3850)
[M::mem_pestat] mean and std.dev: (825.95, 733.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5063)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 113, #reads = 1068883 mem = 536878348 peak = 1123512320
[M::process] read 700278 sequences (100000028 bp) in 2.843 CPU sec, 3.141 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 283175, 38, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (300, 537, 1186)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2958)
[M::mem_pestat] mean and std.dev: (731.91, 664.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3844)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 224, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 667)
[M::mem_pestat] mean and std.dev: (249.76, 122.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 838)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (311, 434, 1469)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3785)
[M::mem_pestat] mean and std.dev: (984.34, 948.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4943)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 322, 578)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1300)
[M::mem_pestat] mean and std.dev: (339.57, 210.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1661)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700288 sequences (100000162 bp) in 2.314 CPU sec, 2.417 real sec...
[M::mem_process_seqs] Processed 700872 reads in 220.349 CPU sec, 7.449 real sec
[M::mem_process_seqs] Processed 700762 reads in 156.681 CPU sec, 5.483 real sec
sorting block 114, #reads = 1070406 mem = 536880613 peak = 1123512320
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 283226, 27, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 232, 525)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1267)
[M::mem_pestat] mean and std.dev: (297.59, 249.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1638)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 225, 327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 671)
[M::mem_pestat] mean and std.dev: (250.88, 122.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 843)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (279, 398, 666)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1440)
[M::mem_pestat] mean and std.dev: (345.96, 208.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1827)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 328, 1038)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2670)
[M::mem_pestat] mean and std.dev: (622.08, 604.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3486)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699790 sequences (100000103 bp) in 2.823 CPU sec, 3.155 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 282919, 17, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 284, 553)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1343)
[M::mem_pestat] mean and std.dev: (368.71, 303.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1738)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 224, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 668)
[M::mem_pestat] mean and std.dev: (250.10, 122.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 839)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (113, 404, 1110)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3104)
[M::mem_pestat] mean and std.dev: (528.07, 717.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4101)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 329, 1094)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2852)
[M::mem_pestat] mean and std.dev: (627.96, 640.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3731)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699814 sequences (100000081 bp) in 2.367 CPU sec, 2.490 real sec...
[M::mem_process_seqs] Processed 700278 reads in 217.080 CPU sec, 7.574 real sec
[M::mem_process_seqs] Processed 700288 reads in 152.834 CPU sec, 5.295 real sec
sorting block 115, #reads = 1071012 mem = 536885275 peak = 1123512320
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 282543, 31, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 794, 798)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2092)
[M::mem_pestat] mean and std.dev: (616.89, 525.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2739)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 226, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 672)
[M::mem_pestat] mean and std.dev: (252.06, 123.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 844)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (386, 516, 1384)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3380)
[M::mem_pestat] mean and std.dev: (813.66, 804.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4378)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 247, 515)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1175)
[M::mem_pestat] mean and std.dev: (342.25, 245.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1505)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698916 sequences (100000205 bp) in 2.722 CPU sec, 3.400 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 282249, 21, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 330, 477)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1125)
[M::mem_pestat] mean and std.dev: (316.44, 213.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1449)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 227, 327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 669)
[M::mem_pestat] mean and std.dev: (250.93, 121.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 840)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (411, 605, 3051)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8331)
[M::mem_pestat] mean and std.dev: (1783.67, 2295.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10971)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 303, 563)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1371)
[M::mem_pestat] mean and std.dev: (367.20, 280.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1775)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698750 sequences (100000146 bp) in 2.267 CPU sec, 2.319 real sec...
[M::mem_process_seqs] Processed 699790 reads in 216.850 CPU sec, 7.452 real sec
sorting block 116, #reads = 1069919 mem = 536881385 peak = 1132175360
[M::mem_process_seqs] Processed 699814 reads in 155.310 CPU sec, 5.315 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 282185, 20, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 326, 894)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2248)
[M::mem_pestat] mean and std.dev: (617.85, 543.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2925)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 229, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 682)
[M::mem_pestat] mean and std.dev: (254.82, 124.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 857)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (93, 1466, 1959)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5691)
[M::mem_pestat] mean and std.dev: (1353.20, 1359.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7557)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 270, 1256)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3362)
[M::mem_pestat] mean and std.dev: (812.70, 991.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4777)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 117, #reads = 1068745 mem = 536878402 peak = 1132175360
[M::process] read 698210 sequences (100000163 bp) in 2.812 CPU sec, 3.615 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 281999, 25, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 352, 923)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2333)
[M::mem_pestat] mean and std.dev: (388.60, 277.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3038)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 229, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 682)
[M::mem_pestat] mean and std.dev: (254.88, 125.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 857)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (295, 888, 1376)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3538)
[M::mem_pestat] mean and std.dev: (930.48, 817.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4619)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 449, 1866)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5172)
[M::mem_pestat] mean and std.dev: (1046.11, 1069.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6825)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698046 sequences (100000153 bp) in 2.384 CPU sec, 2.448 real sec...
[M::mem_process_seqs] Processed 698916 reads in 221.623 CPU sec, 7.848 real sec
[M::mem_process_seqs] Processed 698750 reads in 154.911 CPU sec, 5.421 real sec
sorting block 118, #reads = 1068389 mem = 536878741 peak = 1132175360
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 282076, 27, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 408, 909)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2415)
[M::mem_pestat] mean and std.dev: (528.85, 560.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3168)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 230, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 683)
[M::mem_pestat] mean and std.dev: (255.85, 125.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 858)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (253, 466, 1432)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3790)
[M::mem_pestat] mean and std.dev: (769.46, 763.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4969)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (284, 473, 1151)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2885)
[M::mem_pestat] mean and std.dev: (778.11, 706.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3752)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697848 sequences (100000043 bp) in 2.633 CPU sec, 3.123 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 281933, 30, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (308, 617, 1748)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4628)
[M::mem_pestat] mean and std.dev: (891.91, 901.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6068)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 231, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 683)
[M::mem_pestat] mean and std.dev: (255.90, 124.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 858)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (247, 789, 1661)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4489)
[M::mem_pestat] mean and std.dev: (1096.28, 1087.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5903)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 347, 1035)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2715)
[M::mem_pestat] mean and std.dev: (552.50, 555.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3555)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698128 sequences (100000215 bp) in 2.353 CPU sec, 2.411 real sec...
[M::mem_process_seqs] Processed 698210 reads in 219.114 CPU sec, 7.775 real sec
[M::mem_process_seqs] Processed 698046 reads in 154.098 CPU sec, 5.348 real sec
sorting block 119, #reads = 1069425 mem = 536876990 peak = 1132175360
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 281450, 19, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (292, 414, 2414)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6658)
[M::mem_pestat] mean and std.dev: (1463.38, 1981.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9391)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 231, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 687)
[M::mem_pestat] mean and std.dev: (256.92, 126.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 863)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (562, 1153, 1585)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3631)
[M::mem_pestat] mean and std.dev: (1057.79, 674.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4654)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 306, 738)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1798)
[M::mem_pestat] mean and std.dev: (509.54, 494.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2489)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697822 sequences (100000044 bp) in 2.675 CPU sec, 3.183 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 281716, 39, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 376, 1188)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3134)
[M::mem_pestat] mean and std.dev: (642.60, 624.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4107)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 230, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 683)
[M::mem_pestat] mean and std.dev: (256.04, 125.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 858)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (88, 520, 916)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2572)
[M::mem_pestat] mean and std.dev: (498.38, 505.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3400)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 366, 1491)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4101)
[M::mem_pestat] mean and std.dev: (783.35, 744.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5406)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697838 sequences (100000135 bp) in 2.351 CPU sec, 2.581 real sec...
[M::mem_process_seqs] Processed 697848 reads in 216.443 CPU sec, 7.503 real sec
sorting block 120, #reads = 1068345 mem = 536880577 peak = 1132175360
[M::mem_process_seqs] Processed 698128 reads in 154.258 CPU sec, 5.263 real sec
sorting block 121, #reads = 1068876 mem = 536877728 peak = 1132175360
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 281153, 34, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 378, 998)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2668)
[M::mem_pestat] mean and std.dev: (458.07, 433.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3503)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 231, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 684)
[M::mem_pestat] mean and std.dev: (256.44, 125.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 859)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (386, 693, 1071)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2441)
[M::mem_pestat] mean and std.dev: (634.17, 434.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3126)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (265, 682, 1018)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2524)
[M::mem_pestat] mean and std.dev: (666.03, 485.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3277)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698180 sequences (100000172 bp) in 2.616 CPU sec, 2.664 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 281964, 36, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 226, 455)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1059)
[M::mem_pestat] mean and std.dev: (322.52, 280.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1444)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 231, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 684)
[M::mem_pestat] mean and std.dev: (256.50, 126.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 859)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (266, 946, 1549)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4115)
[M::mem_pestat] mean and std.dev: (986.74, 982.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5398)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 304, 977)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2543)
[M::mem_pestat] mean and std.dev: (483.51, 495.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3326)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697912 sequences (100000151 bp) in 2.190 CPU sec, 2.194 real sec...
[M::mem_process_seqs] Processed 697822 reads in 198.845 CPU sec, 6.335 real sec
[M::mem_process_seqs] Processed 697838 reads in 142.751 CPU sec, 4.536 real sec
sorting block 122, #reads = 1068248 mem = 536880836 peak = 1132175360
[M::process] read 697700 sequences (100000115 bp) in 2.509 CPU sec, 2.555 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 282074, 45, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (252, 340, 1332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3492)
[M::mem_pestat] mean and std.dev: (557.10, 494.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4572)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 230, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 686)
[M::mem_pestat] mean and std.dev: (256.34, 126.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 862)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (375, 728, 1399)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3447)
[M::mem_pestat] mean and std.dev: (781.90, 571.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4471)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 252, 878)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2284)
[M::mem_pestat] mean and std.dev: (533.79, 523.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2987)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697910 sequences (100000046 bp) in 2.391 CPU sec, 2.400 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 281611, 18, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 340, 1016)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2620)
[M::mem_pestat] mean and std.dev: (618.89, 653.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3422)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 230, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 689)
[M::mem_pestat] mean and std.dev: (256.57, 126.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 866)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (747, 1064, 1705)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3621)
[M::mem_pestat] mean and std.dev: (1085.60, 587.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4579)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (258, 365, 601)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1287)
[M::mem_pestat] mean and std.dev: (365.15, 162.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1630)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 282059, 18, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 359, 564)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1386)
[M::mem_pestat] mean and std.dev: (362.69, 272.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1797)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 231, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 687)
[M::mem_pestat] mean and std.dev: (257.27, 126.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 863)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (746, 1115, 2356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5576)
[M::mem_pestat] mean and std.dev: (1616.18, 1512.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7666)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (231, 358, 935)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2343)
[M::mem_pestat] mean and std.dev: (575.55, 546.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3047)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698180 reads in 297.826 CPU sec, 9.525 real sec
[M::mem_process_seqs] Processed 697912 reads in 239.764 CPU sec, 7.729 real sec
sorting block 123, #reads = 1067208 mem = 536880091 peak = 1132175360
[M::mem_process_seqs] Processed 697700 reads in 270.735 CPU sec, 8.784 real sec
[M::process] read 705408 sequences (100000077 bp) in 3.061 CPU sec, 3.452 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 281218, 28, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (241, 491, 2378)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6652)
[M::mem_pestat] mean and std.dev: (1103.50, 1216.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8789)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 231, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 687)
[M::mem_pestat] mean and std.dev: (256.94, 126.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 863)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (71, 430, 1032)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2954)
[M::mem_pestat] mean and std.dev: (513.50, 558.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3915)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 280, 1113)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2961)
[M::mem_pestat] mean and std.dev: (508.59, 497.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3885)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 124, #reads = 1066646 mem = 536878550 peak = 1132175360
[M::process] read 705474 sequences (100000192 bp) in 2.484 CPU sec, 2.729 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 284271, 38, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 333, 1113)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2947)
[M::mem_pestat] mean and std.dev: (561.63, 591.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3864)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 213, 307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 625)
[M::mem_pestat] mean and std.dev: (237.06, 114.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 784)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (230, 835, 1481)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3983)
[M::mem_pestat] mean and std.dev: (849.71, 774.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5234)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (248, 435, 1749)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4751)
[M::mem_pestat] mean and std.dev: (750.96, 939.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6252)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697910 reads in 248.532 CPU sec, 8.052 real sec
[M::process] read 705586 sequences (100000284 bp) in 2.347 CPU sec, 2.422 real sec...
sorting block 125, #reads = 1063137 mem = 536880441 peak = 1132175360
[M::mem_process_seqs] Processed 705408 reads in 181.896 CPU sec, 5.836 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 284695, 16, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (228, 532, 914)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2286)
[M::mem_pestat] mean and std.dev: (615.40, 501.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2972)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 212, 307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 625)
[M::mem_pestat] mean and std.dev: (236.92, 114.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 784)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 729, 2958)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8580)
[M::mem_pestat] mean and std.dev: (1306.69, 1372.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11391)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 283, 873)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2185)
[M::mem_pestat] mean and std.dev: (386.37, 312.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2841)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704584 sequences (100000259 bp) in 2.434 CPU sec, 2.624 real sec...
[M::process] read 703558 sequences (100000051 bp) in 2.294 CPU sec, 2.298 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 284783, 31, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 310, 1458)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3956)
[M::mem_pestat] mean and std.dev: (748.13, 776.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5205)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 212, 305)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 619)
[M::mem_pestat] mean and std.dev: (235.52, 113.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 776)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (353, 790, 1482)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3740)
[M::mem_pestat] mean and std.dev: (940.73, 783.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4869)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 377, 1656)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4518)
[M::mem_pestat] mean and std.dev: (931.70, 989.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5949)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 705474 reads in 211.047 CPU sec, 6.806 real sec
sorting block 126, #reads = 1061861 mem = 536878218 peak = 1132175360
[M::mem_process_seqs] Processed 705586 reads in 151.934 CPU sec, 4.933 real sec
sorting block 127, #reads = 1072672 mem = 536883418 peak = 1133228032
[M::process] read 703154 sequences (100000073 bp) in 2.940 CPU sec, 3.456 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 284348, 17, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 265, 681)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1719)
[M::mem_pestat] mean and std.dev: (382.19, 331.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2238)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 217, 313)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 637)
[M::mem_pestat] mean and std.dev: (241.25, 117.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 799)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 827, 1649)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4569)
[M::mem_pestat] mean and std.dev: (947.50, 867.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6029)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 271, 1149)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3033)
[M::mem_pestat] mean and std.dev: (658.16, 654.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3975)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703558 reads in 119.504 CPU sec, 4.047 real sec
[M::process] read 702614 sequences (100000140 bp) in 2.424 CPU sec, 2.703 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 285051, 16, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 669, 1859)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5251)
[M::mem_pestat] mean and std.dev: (1115.37, 1211.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6947)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 214, 309)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 629)
[M::mem_pestat] mean and std.dev: (238.64, 115.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 789)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (543, 681, 1730)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4104)
[M::mem_pestat] mean and std.dev: (929.31, 670.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5291)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (235, 385, 803)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1939)
[M::mem_pestat] mean and std.dev: (513.03, 462.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2507)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 284310, 30, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 482, 1397)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3767)
[M::mem_pestat] mean and std.dev: (745.68, 641.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4952)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 218, 316)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 646)
[M::mem_pestat] mean and std.dev: (243.54, 119.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 811)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (455, 691, 1202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2696)
[M::mem_pestat] mean and std.dev: (748.54, 489.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3443)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (262, 354, 496)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 964)
[M::mem_pestat] mean and std.dev: (331.00, 156.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1198)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704584 reads in 325.206 CPU sec, 10.870 real sec
sorting block 128, #reads = 1072586 mem = 536883293 peak = 1133228032
[M::process] read 701886 sequences (100000146 bp) in 2.336 CPU sec, 2.494 real sec...
[M::mem_process_seqs] Processed 703154 reads in 179.195 CPU sec, 6.037 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23, 284304, 25, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 291, 950)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2502)
[M::mem_pestat] mean and std.dev: (552.23, 591.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3278)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 219, 317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 647)
[M::mem_pestat] mean and std.dev: (244.02, 119.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 812)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (308, 834, 2229)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6071)
[M::mem_pestat] mean and std.dev: (1023.22, 869.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7992)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 358, 1357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3711)
[M::mem_pestat] mean and std.dev: (837.39, 963.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4888)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 129, #reads = 1074116 mem = 536883044 peak = 1134120960
[M::process] read 700686 sequences (100000101 bp) in 2.546 CPU sec, 2.780 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 283943, 32, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 213, 669)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1661)
[M::mem_pestat] mean and std.dev: (267.67, 174.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2157)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 221, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 657)
[M::mem_pestat] mean and std.dev: (246.42, 120.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 825)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (146, 881, 1949)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5555)
[M::mem_pestat] mean and std.dev: (1056.77, 1077.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7358)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 392, 930)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2386)
[M::mem_pestat] mean and std.dev: (584.57, 481.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3114)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701242 sequences (100000083 bp) in 2.245 CPU sec, 2.276 real sec...
[M::mem_process_seqs] Processed 702614 reads in 202.355 CPU sec, 6.555 real sec
[M::mem_process_seqs] Processed 701886 reads in 143.442 CPU sec, 4.695 real sec
sorting block 130, #reads = 1074469 mem = 536878781 peak = 1134120960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 283573, 25, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 349, 1071)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2909)
[M::mem_pestat] mean and std.dev: (446.64, 424.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3828)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 224, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 667)
[M::mem_pestat] mean and std.dev: (249.57, 121.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 838)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (484, 1213, 2175)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5557)
[M::mem_pestat] mean and std.dev: (1376.44, 1121.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7248)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 336, 1168)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3132)
[M::mem_pestat] mean and std.dev: (665.33, 693.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4114)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700130 sequences (100000140 bp) in 2.596 CPU sec, 3.046 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 283921, 28, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 256, 562)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1318)
[M::mem_pestat] mean and std.dev: (340.32, 245.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1696)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 223, 323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 661)
[M::mem_pestat] mean and std.dev: (247.97, 120.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 830)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (322, 876, 1255)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3121)
[M::mem_pestat] mean and std.dev: (681.50, 472.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4054)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (265, 456, 959)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2347)
[M::mem_pestat] mean and std.dev: (570.69, 486.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3041)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700552 sequences (100000090 bp) in 2.248 CPU sec, 2.254 real sec...
[M::mem_process_seqs] Processed 700686 reads in 198.271 CPU sec, 6.755 real sec
[M::mem_process_seqs] Processed 701242 reads in 138.076 CPU sec, 4.448 real sec
sorting block 131, #reads = 1073609 mem = 536880192 peak = 1134120960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 283875, 27, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 576, 1165)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3191)
[M::mem_pestat] mean and std.dev: (613.50, 535.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4204)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 226, 327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 671)
[M::mem_pestat] mean and std.dev: (250.72, 122.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 843)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (40, 160, 1040)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3040)
[M::mem_pestat] mean and std.dev: (483.25, 730.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4040)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 355, 471)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1051)
[M::mem_pestat] mean and std.dev: (350.19, 197.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1341)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700036 sequences (100000212 bp) in 2.418 CPU sec, 2.548 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 283080, 37, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (265, 334, 1249)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3217)
[M::mem_pestat] mean and std.dev: (621.32, 651.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4201)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 224, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 662)
[M::mem_pestat] mean and std.dev: (249.18, 121.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 831)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 358, 1846)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5226)
[M::mem_pestat] mean and std.dev: (1057.78, 1247.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6916)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (257, 536, 1647)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4427)
[M::mem_pestat] mean and std.dev: (870.82, 774.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5817)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700134 sequences (100000118 bp) in 2.230 CPU sec, 2.254 real sec...
[M::mem_process_seqs] Processed 700130 reads in 197.820 CPU sec, 6.395 real sec
sorting block 132, #reads = 1075523 mem = 536878932 peak = 1134120960
[M::mem_process_seqs] Processed 700552 reads in 137.888 CPU sec, 4.412 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 284078, 33, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 293, 810)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2076)
[M::mem_pestat] mean and std.dev: (468.46, 472.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2709)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 227, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 672)
[M::mem_pestat] mean and std.dev: (251.35, 122.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 844)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (561, 1078, 3280)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8718)
[M::mem_pestat] mean and std.dev: (1593.59, 1535.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11437)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (242, 295, 892)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2192)
[M::mem_pestat] mean and std.dev: (485.35, 496.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2842)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 133, #reads = 1073349 mem = 536881436 peak = 1134120960
[M::process] read 699868 sequences (100000027 bp) in 2.774 CPU sec, 2.923 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 283453, 39, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 270, 546)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1256)
[M::mem_pestat] mean and std.dev: (369.11, 280.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1611)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 226, 327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 669)
[M::mem_pestat] mean and std.dev: (250.95, 121.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 840)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (314, 645, 1490)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3842)
[M::mem_pestat] mean and std.dev: (943.78, 996.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5018)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 484, 1037)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2689)
[M::mem_pestat] mean and std.dev: (636.10, 489.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3515)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699700 sequences (100000213 bp) in 2.317 CPU sec, 2.317 real sec...
[M::mem_process_seqs] Processed 700036 reads in 200.805 CPU sec, 6.427 real sec
[M::mem_process_seqs] Processed 700134 reads in 140.472 CPU sec, 4.483 real sec
sorting block 134, #reads = 1073018 mem = 536882410 peak = 1134120960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 283202, 29, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 358, 680)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1612)
[M::mem_pestat] mean and std.dev: (415.84, 322.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2078)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 227, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 672)
[M::mem_pestat] mean and std.dev: (251.56, 122.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 844)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (490, 1266, 3098)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8314)
[M::mem_pestat] mean and std.dev: (1670.69, 1511.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10922)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (267, 478, 1788)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4830)
[M::mem_pestat] mean and std.dev: (804.23, 787.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6351)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700262 sequences (100000064 bp) in 2.741 CPU sec, 3.076 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 283080, 37, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 497, 898)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2332)
[M::mem_pestat] mean and std.dev: (370.95, 278.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3049)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 227, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 672)
[M::mem_pestat] mean and std.dev: (251.63, 122.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 844)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 483, 1731)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4849)
[M::mem_pestat] mean and std.dev: (796.12, 866.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6408)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (266, 448, 997)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2459)
[M::mem_pestat] mean and std.dev: (600.74, 475.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3190)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700098 sequences (100000147 bp) in 2.348 CPU sec, 2.378 real sec...
[M::mem_process_seqs] Processed 699868 reads in 199.077 CPU sec, 6.584 real sec
[M::mem_process_seqs] Processed 699700 reads in 139.212 CPU sec, 4.657 real sec
sorting block 135, #reads = 1072106 mem = 536879573 peak = 1134120960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 283094, 28, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 431, 558)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1310)
[M::mem_pestat] mean and std.dev: (424.52, 278.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1686)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 226, 327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 671)
[M::mem_pestat] mean and std.dev: (251.09, 122.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 843)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 926, 1318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3536)
[M::mem_pestat] mean and std.dev: (733.00, 633.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4645)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (232, 492, 750)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1786)
[M::mem_pestat] mean and std.dev: (490.88, 323.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2304)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700718 sequences (100000113 bp) in 2.533 CPU sec, 2.723 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 283146, 28, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (235, 389, 626)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1408)
[M::mem_pestat] mean and std.dev: (392.83, 236.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1799)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 225, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 665)
[M::mem_pestat] mean and std.dev: (249.61, 121.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 835)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (128, 446, 1076)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2972)
[M::mem_pestat] mean and std.dev: (605.27, 682.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3920)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (139, 291, 589)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1489)
[M::mem_pestat] mean and std.dev: (360.69, 284.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1939)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700176 sequences (100000099 bp) in 2.223 CPU sec, 2.455 real sec...
[M::mem_process_seqs] Processed 700262 reads in 211.076 CPU sec, 7.095 real sec
sorting block 136, #reads = 1072818 mem = 536880311 peak = 1134120960
[M::mem_process_seqs] Processed 700098 reads in 145.696 CPU sec, 4.935 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 283586, 27, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (144, 246, 1211)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3345)
[M::mem_pestat] mean and std.dev: (666.08, 824.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4412)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 223, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 655)
[M::mem_pestat] mean and std.dev: (246.84, 119.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 822)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (429, 906, 2135)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5547)
[M::mem_pestat] mean and std.dev: (1171.15, 1063.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7253)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (241, 545, 1261)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3301)
[M::mem_pestat] mean and std.dev: (813.46, 746.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4321)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 137, #reads = 1072830 mem = 536879211 peak = 1134120960
[M::process] read 700668 sequences (100000003 bp) in 2.816 CPU sec, 3.440 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 283258, 21, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 385, 1447)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3931)
[M::mem_pestat] mean and std.dev: (676.18, 700.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5173)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 224, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 665)
[M::mem_pestat] mean and std.dev: (249.22, 120.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 835)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (466, 1532, 7857)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 22639)
[M::mem_pestat] mean and std.dev: (3619.00, 3392.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 30030)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 437, 1814)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4994)
[M::mem_pestat] mean and std.dev: (955.82, 1027.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6584)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700718 reads in 206.319 CPU sec, 6.818 real sec
[M::process] read 700986 sequences (100000261 bp) in 2.405 CPU sec, 2.501 real sec...
[M::mem_process_seqs] Processed 700176 reads in 147.125 CPU sec, 4.816 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 283417, 37, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (273, 469, 1115)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2799)
[M::mem_pestat] mean and std.dev: (577.97, 559.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3641)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 223, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 658)
[M::mem_pestat] mean and std.dev: (247.87, 120.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 826)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (248, 536, 1402)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3710)
[M::mem_pestat] mean and std.dev: (846.92, 892.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4864)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (330, 589, 1441)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3663)
[M::mem_pestat] mean and std.dev: (772.50, 659.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4774)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 138, #reads = 1073377 mem = 536881189 peak = 1134120960
[M::process] read 699844 sequences (100000289 bp) in 2.847 CPU sec, 3.554 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 283842, 34, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (244, 309, 619)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1369)
[M::mem_pestat] mean and std.dev: (416.67, 245.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1744)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 223, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 658)
[M::mem_pestat] mean and std.dev: (247.80, 121.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 826)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (82, 452, 1084)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3088)
[M::mem_pestat] mean and std.dev: (479.70, 475.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4090)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 337, 781)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1959)
[M::mem_pestat] mean and std.dev: (420.47, 324.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2548)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700668 reads in 210.490 CPU sec, 7.271 real sec
[M::process] read 699478 sequences (100000110 bp) in 2.599 CPU sec, 2.874 real sec...
[M::mem_process_seqs] Processed 700986 reads in 150.259 CPU sec, 5.516 real sec
sorting block 139, #reads = 1071474 mem = 536880198 peak = 1134120960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 283113, 30, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 354, 497)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1159)
[M::mem_pestat] mean and std.dev: (306.69, 165.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1490)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 227, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 672)
[M::mem_pestat] mean and std.dev: (252.20, 123.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 844)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (139, 850, 1688)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4786)
[M::mem_pestat] mean and std.dev: (1070.21, 1084.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6335)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 399, 1256)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3404)
[M::mem_pestat] mean and std.dev: (578.64, 503.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4478)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699016 sequences (100000153 bp) in 2.677 CPU sec, 2.933 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 283155, 27, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (277, 352, 439)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 763)
[M::mem_pestat] mean and std.dev: (343.80, 133.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 925)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 228, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 681)
[M::mem_pestat] mean and std.dev: (253.86, 125.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 856)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 693, 2281)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6455)
[M::mem_pestat] mean and std.dev: (1118.64, 1156.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8542)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 531, 869)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2193)
[M::mem_pestat] mean and std.dev: (512.57, 395.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2855)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698722 sequences (100000084 bp) in 2.209 CPU sec, 2.212 real sec...
[M::mem_process_seqs] Processed 699844 reads in 211.086 CPU sec, 6.997 real sec
sorting block 140, #reads = 1071072 mem = 536883116 peak = 1134120960
[M::mem_process_seqs] Processed 699478 reads in 147.069 CPU sec, 4.709 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 282393, 31, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 466, 568)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1268)
[M::mem_pestat] mean and std.dev: (366.13, 207.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1618)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 228, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 679)
[M::mem_pestat] mean and std.dev: (253.82, 124.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 853)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (138, 524, 1125)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3099)
[M::mem_pestat] mean and std.dev: (713.07, 643.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4086)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (238, 317, 573)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1243)
[M::mem_pestat] mean and std.dev: (379.26, 242.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1578)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 141, #reads = 1070790 mem = 536879586 peak = 1134120960
[M::process] read 698716 sequences (100000073 bp) in 2.822 CPU sec, 2.931 real sec...
[M::process] read 697990 sequences (100000060 bp) in 2.033 CPU sec, 2.034 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 282289, 37, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 242, 902)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2398)
[M::mem_pestat] mean and std.dev: (470.02, 502.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3146)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 229, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 682)
[M::mem_pestat] mean and std.dev: (254.47, 124.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 857)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (375, 631, 1558)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3924)
[M::mem_pestat] mean and std.dev: (797.03, 696.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5107)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 299, 725)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1795)
[M::mem_pestat] mean and std.dev: (467.19, 380.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2330)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699016 reads in 204.062 CPU sec, 6.535 real sec
[M::mem_process_seqs] Processed 698722 reads in 138.692 CPU sec, 4.431 real sec
sorting block 142, #reads = 1070179 mem = 536876912 peak = 1134120960
[M::process] read 698982 sequences (100000120 bp) in 2.312 CPU sec, 2.364 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 282333, 25, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (225, 728, 1538)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4164)
[M::mem_pestat] mean and std.dev: (867.09, 687.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5477)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 230, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 683)
[M::mem_pestat] mean and std.dev: (255.40, 125.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 858)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (250, 584, 1560)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4180)
[M::mem_pestat] mean and std.dev: (524.45, 432.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5490)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 389, 1463)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3983)
[M::mem_pestat] mean and std.dev: (789.72, 808.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5243)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699464 sequences (100000144 bp) in 1.767 CPU sec, 1.771 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 282405, 21, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 341, 660)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1562)
[M::mem_pestat] mean and std.dev: (414.29, 307.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2013)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 231, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 684)
[M::mem_pestat] mean and std.dev: (256.24, 125.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 859)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 638, 1875)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5281)
[M::mem_pestat] mean and std.dev: (878.71, 781.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6984)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 318, 974)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2496)
[M::mem_pestat] mean and std.dev: (498.97, 435.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3257)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 282191, 32, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (139, 284, 1097)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3013)
[M::mem_pestat] mean and std.dev: (491.05, 489.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3971)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 227, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 673)
[M::mem_pestat] mean and std.dev: (253.16, 124.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 845)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (270, 388, 1601)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4263)
[M::mem_pestat] mean and std.dev: (776.59, 959.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5594)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 397, 1842)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5128)
[M::mem_pestat] mean and std.dev: (808.05, 954.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6771)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698716 reads in 267.695 CPU sec, 8.571 real sec
[M::mem_process_seqs] Processed 697990 reads in 211.817 CPU sec, 6.791 real sec
sorting block 143, #reads = 1069325 mem = 536881224 peak = 1134120960
[M::mem_process_seqs] Processed 698982 reads in 237.818 CPU sec, 7.629 real sec
sorting block 144, #reads = 1070494 mem = 536878764 peak = 1134120960
[M::process] read 698790 sequences (100000285 bp) in 2.832 CPU sec, 2.952 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 282675, 23, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 332, 914)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2342)
[M::mem_pestat] mean and std.dev: (533.92, 517.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3056)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 226, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 666)
[M::mem_pestat] mean and std.dev: (250.88, 122.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 836)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (513, 860, 1034)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2076)
[M::mem_pestat] mean and std.dev: (605.28, 362.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2597)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 285, 915)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2399)
[M::mem_pestat] mean and std.dev: (490.44, 462.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3141)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705420 sequences (100000042 bp) in 2.438 CPU sec, 2.453 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 282378, 32, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 293, 995)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2541)
[M::mem_pestat] mean and std.dev: (498.98, 524.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3314)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 229, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 679)
[M::mem_pestat] mean and std.dev: (254.29, 125.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 853)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (226, 517, 913)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2287)
[M::mem_pestat] mean and std.dev: (557.00, 430.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2974)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 394, 1341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3605)
[M::mem_pestat] mean and std.dev: (626.29, 553.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4737)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699464 reads in 203.154 CPU sec, 6.428 real sec
[M::process] read 708678 sequences (100000053 bp) in 2.258 CPU sec, 2.269 real sec...
[M::mem_process_seqs] Processed 698790 reads in 152.849 CPU sec, 4.820 real sec
sorting block 145, #reads = 1066483 mem = 536880390 peak = 1134120960
[M::process] read 708386 sequences (100000148 bp) in 2.708 CPU sec, 2.757 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 284929, 30, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 332, 532)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1202)
[M::mem_pestat] mean and std.dev: (304.40, 171.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1537)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 206, 297)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 601)
[M::mem_pestat] mean and std.dev: (229.63, 110.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 753)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (666, 1099, 1858)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4242)
[M::mem_pestat] mean and std.dev: (1260.36, 871.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5434)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 216, 659)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1619)
[M::mem_pestat] mean and std.dev: (363.73, 315.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2099)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 708588 sequences (100000269 bp) in 2.180 CPU sec, 2.183 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 283852, 13, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 463, 1278)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3432)
[M::mem_pestat] mean and std.dev: (668.54, 581.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4509)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 212, 306)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 622)
[M::mem_pestat] mean and std.dev: (236.43, 114.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 780)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (412, 593, 2352)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6232)
[M::mem_pestat] mean and std.dev: (964.31, 938.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8172)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 347, 1157)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3039)
[M::mem_pestat] mean and std.dev: (538.84, 595.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3980)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 708678 reads in 206.809 CPU sec, 6.549 real sec
sorting block 146, #reads = 1061488 mem = 536890566 peak = 1134120960
[M::mem_process_seqs] Processed 705420 reads in 239.120 CPU sec, 7.585 real sec
[M::process] read 707988 sequences (100000102 bp) in 2.584 CPU sec, 2.662 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 286080, 19, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (129, 396, 862)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2328)
[M::mem_pestat] mean and std.dev: (497.29, 516.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3061)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 207, 297)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 601)
[M::mem_pestat] mean and std.dev: (230.09, 110.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 753)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (641, 1797, 2919)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7475)
[M::mem_pestat] mean and std.dev: (2009.32, 1623.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9753)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 242, 726)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1862)
[M::mem_pestat] mean and std.dev: (421.73, 397.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2430)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706998 sequences (100000055 bp) in 1.770 CPU sec, 1.771 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 285253, 26, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 211, 717)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1773)
[M::mem_pestat] mean and std.dev: (345.92, 333.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2301)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 205, 295)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 595)
[M::mem_pestat] mean and std.dev: (229.08, 109.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 745)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (304, 433, 2296)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6280)
[M::mem_pestat] mean and std.dev: (994.24, 1155.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8272)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (269, 746, 1371)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3575)
[M::mem_pestat] mean and std.dev: (1033.73, 913.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4689)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 708386 reads in 206.029 CPU sec, 6.539 real sec
sorting block 147, #reads = 1061216 mem = 536884650 peak = 1134120960
[M::mem_process_seqs] Processed 708588 reads in 235.223 CPU sec, 7.491 real sec
sorting block 148, #reads = 1069011 mem = 536881564 peak = 1134120960
[M::process] read 706570 sequences (100000270 bp) in 2.302 CPU sec, 2.345 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 286008, 22, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 293, 505)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1169)
[M::mem_pestat] mean and std.dev: (362.71, 298.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1555)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 207, 298)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 602)
[M::mem_pestat] mean and std.dev: (231.01, 110.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 754)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (88, 397, 1036)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2932)
[M::mem_pestat] mean and std.dev: (528.95, 562.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3880)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 345, 620)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1486)
[M::mem_pestat] mean and std.dev: (390.08, 307.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1919)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706396 sequences (100000000 bp) in 1.710 CPU sec, 1.717 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23, 285657, 23, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 333, 2154)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6048)
[M::mem_pestat] mean and std.dev: (968.86, 1308.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7995)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 209, 300)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 606)
[M::mem_pestat] mean and std.dev: (232.38, 111.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 759)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (138, 699, 1019)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2781)
[M::mem_pestat] mean and std.dev: (627.83, 427.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3662)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 494, 862)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2150)
[M::mem_pestat] mean and std.dev: (530.38, 393.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2794)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 284879, 42, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (263, 689, 1063)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2663)
[M::mem_pestat] mean and std.dev: (655.71, 477.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3463)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 210, 302)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 612)
[M::mem_pestat] mean and std.dev: (233.77, 112.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 767)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (294, 609, 2199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6009)
[M::mem_pestat] mean and std.dev: (1170.86, 1189.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7914)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 289, 638)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1514)
[M::mem_pestat] mean and std.dev: (343.53, 256.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1952)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 707988 reads in 292.616 CPU sec, 9.401 real sec
[M::mem_process_seqs] Processed 706998 reads in 222.332 CPU sec, 7.140 real sec
sorting block 149, #reads = 1065310 mem = 536882712 peak = 1134120960
[M::mem_process_seqs] Processed 706570 reads in 249.058 CPU sec, 7.999 real sec
sorting block 150, #reads = 1068157 mem = 536877272 peak = 1134120960
[M::process] read 704262 sequences (100000005 bp) in 2.510 CPU sec, 2.623 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 285093, 31, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 272, 510)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1192)
[M::mem_pestat] mean and std.dev: (362.65, 284.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1533)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 210, 302)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 612)
[M::mem_pestat] mean and std.dev: (233.74, 112.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 767)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 383, 1020)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2742)
[M::mem_pestat] mean and std.dev: (571.07, 518.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3603)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (328, 591, 1027)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2425)
[M::mem_pestat] mean and std.dev: (750.79, 624.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3249)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703522 sequences (100000230 bp) in 1.871 CPU sec, 1.909 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 285008, 19, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 250, 735)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1805)
[M::mem_pestat] mean and std.dev: (344.95, 362.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2340)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 215, 310)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 630)
[M::mem_pestat] mean and std.dev: (238.89, 115.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 790)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 253, 2434)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6868)
[M::mem_pestat] mean and std.dev: (1058.42, 1214.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9085)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 284, 1583)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4357)
[M::mem_pestat] mean and std.dev: (803.85, 984.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5744)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702874 sequences (100000219 bp) in 1.620 CPU sec, 1.615 real sec...
[M::mem_process_seqs] Processed 706396 reads in 188.143 CPU sec, 5.959 real sec
[M::mem_process_seqs] Processed 704262 reads in 123.748 CPU sec, 3.926 real sec
sorting block 151, #reads = 1064600 mem = 536878314 peak = 1134120960
[M::process] read 702420 sequences (100000193 bp) in 2.173 CPU sec, 2.283 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 284462, 20, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (126, 219, 782)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2094)
[M::mem_pestat] mean and std.dev: (368.80, 348.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2750)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 218, 315)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 643)
[M::mem_pestat] mean and std.dev: (242.61, 117.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 807)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (504, 980, 1998)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4986)
[M::mem_pestat] mean and std.dev: (1156.05, 978.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6480)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 419, 1464)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3988)
[M::mem_pestat] mean and std.dev: (819.31, 950.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5250)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702288 sequences (100000026 bp) in 1.650 CPU sec, 1.647 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 284301, 25, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 388, 1050)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2716)
[M::mem_pestat] mean and std.dev: (640.78, 684.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3549)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 220, 319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 653)
[M::mem_pestat] mean and std.dev: (245.47, 119.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 820)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (301, 1698, 3439)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9715)
[M::mem_pestat] mean and std.dev: (2078.40, 2189.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12853)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 328, 729)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1863)
[M::mem_pestat] mean and std.dev: (446.61, 374.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2430)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 284511, 23, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (229, 699, 795)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1927)
[M::mem_pestat] mean and std.dev: (530.06, 317.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2493)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 219, 316)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 644)
[M::mem_pestat] mean and std.dev: (243.75, 118.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 808)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (460, 1189, 1738)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4294)
[M::mem_pestat] mean and std.dev: (1087.73, 834.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5572)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 353, 1216)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3282)
[M::mem_pestat] mean and std.dev: (673.26, 610.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4315)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703522 reads in 244.428 CPU sec, 7.789 real sec
[M::mem_process_seqs] Processed 702420 reads in 187.676 CPU sec, 6.014 real sec
sorting block 152, #reads = 1069208 mem = 536879647 peak = 1134120960
[M::mem_process_seqs] Processed 702874 reads in 210.061 CPU sec, 6.763 real sec
sorting block 153, #reads = 1070954 mem = 536880362 peak = 1134120960
[M::process] read 701738 sequences (100000228 bp) in 2.359 CPU sec, 2.483 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 283839, 37, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 481, 704)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1748)
[M::mem_pestat] mean and std.dev: (407.21, 271.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2270)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 220, 320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 656)
[M::mem_pestat] mean and std.dev: (246.39, 121.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 824)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (524, 911, 2432)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6248)
[M::mem_pestat] mean and std.dev: (1394.32, 1282.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8156)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (289, 525, 1535)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4027)
[M::mem_pestat] mean and std.dev: (855.60, 819.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5273)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701736 sequences (100000119 bp) in 1.786 CPU sec, 1.830 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 284279, 24, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 413, 885)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2283)
[M::mem_pestat] mean and std.dev: (506.85, 449.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2982)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 221, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 657)
[M::mem_pestat] mean and std.dev: (247.03, 121.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 825)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (279, 884, 1729)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4629)
[M::mem_pestat] mean and std.dev: (888.04, 740.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6079)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (273, 384, 914)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2196)
[M::mem_pestat] mean and std.dev: (463.48, 327.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2837)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702288 reads in 178.878 CPU sec, 5.681 real sec
[M::process] read 701488 sequences (100000123 bp) in 1.610 CPU sec, 1.603 real sec...
sorting block 154, #reads = 1070773 mem = 536878922 peak = 1134120960
[M::mem_process_seqs] Processed 701738 reads in 120.153 CPU sec, 3.789 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 283670, 33, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (254, 451, 888)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2156)
[M::mem_pestat] mean and std.dev: (660.56, 569.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2940)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 221, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 659)
[M::mem_pestat] mean and std.dev: (246.43, 120.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 828)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (401, 972, 2607)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7019)
[M::mem_pestat] mean and std.dev: (1255.47, 1177.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9225)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 352, 1415)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3799)
[M::mem_pestat] mean and std.dev: (688.52, 802.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4991)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701656 sequences (100000079 bp) in 2.237 CPU sec, 2.322 real sec...
[M::process] read 700774 sequences (100000186 bp) in 1.639 CPU sec, 1.639 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 283715, 29, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 257, 893)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2311)
[M::mem_pestat] mean and std.dev: (424.18, 385.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3020)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 222, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 660)
[M::mem_pestat] mean and std.dev: (247.95, 121.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 829)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (431, 952, 2331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6131)
[M::mem_pestat] mean and std.dev: (1276.24, 1017.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8031)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 261, 588)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1426)
[M::mem_pestat] mean and std.dev: (331.12, 264.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1845)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701736 reads in 162.276 CPU sec, 5.141 real sec
sorting block 155, #reads = 1071225 mem = 536878864 peak = 1134120960
[M::mem_process_seqs] Processed 701488 reads in 108.490 CPU sec, 3.451 real sec
sorting block 156, #reads = 1071015 mem = 536877138 peak = 1134555136
[M::process] read 700568 sequences (100000151 bp) in 1.971 CPU sec, 2.025 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 283257, 25, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 333, 773)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1917)
[M::mem_pestat] mean and std.dev: (457.62, 377.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2489)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 222, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 660)
[M::mem_pestat] mean and std.dev: (247.73, 121.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 829)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (566, 2149, 2730)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7058)
[M::mem_pestat] mean and std.dev: (1899.96, 1423.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9222)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 319, 899)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2375)
[M::mem_pestat] mean and std.dev: (491.16, 420.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3113)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699612 sequences (100000232 bp) in 1.610 CPU sec, 1.604 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 283293, 16, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (223, 453, 1291)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3427)
[M::mem_pestat] mean and std.dev: (740.34, 723.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4495)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 224, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 667)
[M::mem_pestat] mean and std.dev: (250.00, 123.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 838)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (547, 960, 1459)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3283)
[M::mem_pestat] mean and std.dev: (1025.44, 811.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4270)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 358, 714)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1734)
[M::mem_pestat] mean and std.dev: (492.11, 373.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2244)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 283216, 30, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 212, 451)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1051)
[M::mem_pestat] mean and std.dev: (276.33, 205.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1351)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 224, 327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 671)
[M::mem_pestat] mean and std.dev: (250.88, 123.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 843)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (376, 513, 1496)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3736)
[M::mem_pestat] mean and std.dev: (844.83, 641.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4856)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 268, 582)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1346)
[M::mem_pestat] mean and std.dev: (331.40, 250.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1728)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701656 reads in 219.680 CPU sec, 6.996 real sec
[M::mem_process_seqs] Processed 700774 reads in 169.770 CPU sec, 5.427 real sec
sorting block 157, #reads = 1070676 mem = 536878841 peak = 1134555136
[M::mem_process_seqs] Processed 700568 reads in 189.492 CPU sec, 6.062 real sec
sorting block 158, #reads = 1071160 mem = 536880064 peak = 1134555136
[M::process] read 699644 sequences (100000072 bp) in 2.437 CPU sec, 2.531 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 282865, 34, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 268, 491)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1047)
[M::mem_pestat] mean and std.dev: (286.30, 171.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1325)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 226, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 675)
[M::mem_pestat] mean and std.dev: (252.30, 123.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 848)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (658, 1320, 1465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3079)
[M::mem_pestat] mean and std.dev: (1161.34, 593.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3886)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 445, 1199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3153)
[M::mem_pestat] mean and std.dev: (658.70, 647.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4130)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699642 sequences (100000073 bp) in 1.755 CPU sec, 1.772 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 283117, 11, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 239, 820)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2154)
[M::mem_pestat] mean and std.dev: (408.36, 449.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2821)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 227, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 675)
[M::mem_pestat] mean and std.dev: (252.43, 123.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 848)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (605, 785, 2553)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6449)
[M::mem_pestat] mean and std.dev: (1460.18, 1326.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8397)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (245, 480, 1076)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2738)
[M::mem_pestat] mean and std.dev: (531.12, 374.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3569)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699612 reads in 156.465 CPU sec, 4.951 real sec
[M::process] read 698886 sequences (100000082 bp) in 1.690 CPU sec, 1.691 real sec...
[M::mem_process_seqs] Processed 699644 reads in 106.757 CPU sec, 3.358 real sec
sorting block 159, #reads = 1070990 mem = 536881375 peak = 1134555136
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 283150, 14, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 332, 1176)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3196)
[M::mem_pestat] mean and std.dev: (624.49, 602.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4206)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 227, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 681)
[M::mem_pestat] mean and std.dev: (253.21, 124.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 856)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (344, 1050, 1054)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2474)
[M::mem_pestat] mean and std.dev: (764.85, 590.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3184)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 276, 742)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1846)
[M::mem_pestat] mean and std.dev: (310.04, 195.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2398)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698332 sequences (100000094 bp) in 2.082 CPU sec, 2.138 real sec...
[M::process] read 698140 sequences (100000131 bp) in 1.610 CPU sec, 1.618 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 282785, 20, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (278, 417, 870)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2054)
[M::mem_pestat] mean and std.dev: (556.84, 451.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2646)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 229, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 685)
[M::mem_pestat] mean and std.dev: (255.33, 125.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 861)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 705, 1633)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4561)
[M::mem_pestat] mean and std.dev: (1073.55, 1243.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6046)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 344, 1235)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3321)
[M::mem_pestat] mean and std.dev: (668.31, 807.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4364)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699642 reads in 159.298 CPU sec, 5.057 real sec
sorting block 160, #reads = 1070682 mem = 536878465 peak = 1134555136
[M::mem_process_seqs] Processed 698886 reads in 109.470 CPU sec, 3.485 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 282582, 31, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 329, 1115)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2995)
[M::mem_pestat] mean and std.dev: (640.84, 773.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3935)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 231, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 692)
[M::mem_pestat] mean and std.dev: (257.17, 126.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 870)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (293, 707, 1206)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3032)
[M::mem_pestat] mean and std.dev: (862.57, 712.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3945)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 370, 591)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1355)
[M::mem_pestat] mean and std.dev: (411.36, 278.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1737)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698238 sequences (100000033 bp) in 2.236 CPU sec, 2.302 real sec...
[M::process] read 698306 sequences (100000232 bp) in 1.650 CPU sec, 1.652 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 282360, 30, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (390, 478, 713)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1359)
[M::mem_pestat] mean and std.dev: (507.65, 243.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1682)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 233, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 696)
[M::mem_pestat] mean and std.dev: (258.43, 126.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 875)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (291, 708, 2129)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5805)
[M::mem_pestat] mean and std.dev: (1180.81, 1249.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7643)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 252, 454)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1034)
[M::mem_pestat] mean and std.dev: (295.08, 191.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1324)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698332 reads in 162.237 CPU sec, 5.134 real sec
sorting block 161, #reads = 1073021 mem = 536879029 peak = 1134555136
[M::mem_process_seqs] Processed 698140 reads in 111.212 CPU sec, 3.542 real sec
sorting block 162, #reads = 1071714 mem = 536886794 peak = 1134555136
[M::process] read 697602 sequences (100000263 bp) in 2.134 CPU sec, 2.168 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (19, 281995, 21, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 303, 760)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1898)
[M::mem_pestat] mean and std.dev: (398.82, 313.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2467)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 232, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 692)
[M::mem_pestat] mean and std.dev: (257.25, 125.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 870)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (356, 1611, 2640)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7208)
[M::mem_pestat] mean and std.dev: (1470.48, 1118.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9492)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (236, 322, 952)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2384)
[M::mem_pestat] mean and std.dev: (555.27, 566.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3100)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696786 sequences (100000145 bp) in 1.628 CPU sec, 1.634 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 282407, 22, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 326, 1229)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3293)
[M::mem_pestat] mean and std.dev: (757.03, 812.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4325)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 232, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 689)
[M::mem_pestat] mean and std.dev: (256.69, 125.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 866)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (378, 1165, 1431)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3537)
[M::mem_pestat] mean and std.dev: (941.60, 732.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4590)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 514, 1059)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2803)
[M::mem_pestat] mean and std.dev: (587.48, 525.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3675)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698238 reads in 164.737 CPU sec, 5.226 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 282146, 24, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 283, 758)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1874)
[M::mem_pestat] mean and std.dev: (391.57, 331.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2432)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 233, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 693)
[M::mem_pestat] mean and std.dev: (257.96, 125.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 871)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (367, 2071, 2644)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7198)
[M::mem_pestat] mean and std.dev: (1846.09, 1636.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9475)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 394, 1770)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4866)
[M::mem_pestat] mean and std.dev: (1040.09, 1170.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6414)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 617640 sequences (88516366 bp) in 1.632 CPU sec, 1.642 real sec...
[M::mem_process_seqs] Processed 698306 reads in 182.077 CPU sec, 5.776 real sec
sorting block 163, #reads = 1071190 mem = 536878526 peak = 1134555136
[M::mem_process_seqs] Processed 697602 reads in 204.777 CPU sec, 6.522 real sec
sorting block 164, #reads = 1069698 mem = 536877737 peak = 1177120768
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 281810, 40, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 484, 1031)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2731)
[M::mem_pestat] mean and std.dev: (599.18, 538.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3581)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 235, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 695)
[M::mem_pestat] mean and std.dev: (259.53, 125.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 873)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (97, 192, 1027)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2887)
[M::mem_pestat] mean and std.dev: (469.30, 613.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3817)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (254, 535, 1431)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3785)
[M::mem_pestat] mean and std.dev: (841.88, 761.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4962)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 249812, 27, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (236, 344, 1291)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3401)
[M::mem_pestat] mean and std.dev: (803.31, 885.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4456)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 231, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 681)
[M::mem_pestat] mean and std.dev: (255.52, 123.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 855)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (243, 637, 1206)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3132)
[M::mem_pestat] mean and std.dev: (650.16, 562.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4095)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 539, 1219)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3327)
[M::mem_pestat] mean and std.dev: (604.89, 540.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4381)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696786 reads in 149.989 CPU sec, 4.853 real sec
[M::mem_process_seqs] Processed 617640 reads in 103.430 CPU sec, 3.339 real sec
sorting block 165, #reads = 1069621 mem = 536878875 peak = 1177120768
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000c06f2
  features: bfebfbff 7ffefbff
  extended: f3bfb7ef fb417ffe
  amd bits: 2c100800 00000121
     brand: INTEL(R) XEON(R) PLATINUM 8559C
threads: 31
algo: bwa-mem
license: sentieon:klib=31
reads: 176904442
overall: 70579650560 mem 29988.480 user 553.332 sys 1011.240 real
[main] Version: 0.7.17-r1188
[main] CMD: /opt/conda/share/sentieon-202308.03-3/libexec/bwa mem -K 100000000 -Y -R @RG\tID:A23MHWWLT4.1029_HTI-T1-TDNA-1_A23MHWWLT4_1.L006\tPU:L006\tSM:1029_HTI-T1-TDNA-1_A23MHWWLT4_1\tLB:1029_HTI-T1-TDNA-1_A23MHWWLT4_1\tDS:s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta\tPL:ILLUMINA -t 31 ./BWAIndex/Homo_sapiens_assembly38.fasta.64 1029_HTI-T1-TDNA-1_A23MHWWLT4_1_R1.fastq.gz 1029_HTI-T1-TDNA-1_A23MHWWLT4_1_R2.fastq.gz
[main] Real time: 1011.286 sec; CPU: 30541.815 sec
sorting block 166, #reads = 461642 mem = 232849578 peak = 1177120768
uniq header count 1
merging 167 blocks
sw version: sentieon-genomics-202308.03
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000c06f2
  features: bfebfbff 7ffefbff
  extended: f3bfb7ef fb417ffe
  amd bits: 2c100800 00000121
     brand: INTEL(R) XEON(R) PLATINUM 8559C
threads: 31 max 192
algo: util-sort
license: sentieon:util=1
output file size: 10158368007
output reads: 178299545
bam_mem_sort: 167 calls 102.199 user 2.986 sys 108.264 real
bam_write: 167 calls 113.532 user 7.343 sys 228.110 real
execute: 1 calls 52.997 user 1.918 sys 1079.428 real
merge_files: 1 calls 52.968 user 1.881 sys 67.686 real
parse_chunk: 2663 calls 157.805 user 36.604 sys 242.718 real
read_chunk: 7207 calls 81.442 user 42.237 sys 963.975 real
sort_block: 1 calls 64.014 user 41.847 sys 937.655 real
write_chunk: 4542 calls 52.634 user 1.474 sys 66.636 real
overall: 3760021504 mem 2749.738 user 112.461 sys 1079.456 real
ls: cannot access '*.cram': No such file or directory