cmdline: /opt/conda/share/sentieon-202308.03-3/libexec/util sort -r Homo_sapiens_assembly38.fasta -t 31 -o 1029_FZX-T1-TDNA-1_A23MHWWLT4_1.bam --sam2bam -
This software is licensed to bgold@natera.com by Sentieon Inc.
This software is licensed to bgold@natera.com by Sentieon Inc.
version: sentieon-genomics-202308.03
[M::bwa_idx_load_from_disk] read 3171 ALT contigs
[M::main_mem] bwa index loaded in 8461.101 CPU sec, 284.131 real sec
[M::process] read 684428 sequences (100000296 bp) in 1.427 CPU sec, 1.426 real sec...
[M::process] read 684208 sequences (100000158 bp) in 3.090 CPU sec, 3.363 real sec...
[M::process] read 683970 sequences (100000279 bp) in 2.653 CPU sec, 2.661 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 278279, 9, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 271, 408)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 896)
[M::mem_pestat] mean and std.dev: (300.18, 167.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1140)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 316, 443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 919)
[M::mem_pestat] mean and std.dev: (335.15, 162.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1157)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (369, 419, 566)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 960)
[M::mem_pestat] mean and std.dev: (398.49, 140.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1157)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 683880 sequences (100000035 bp) in 2.851 CPU sec, 2.855 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 278200, 6, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (241, 304, 448)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 862)
[M::mem_pestat] mean and std.dev: (328.64, 141.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1069)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 318, 444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 918)
[M::mem_pestat] mean and std.dev: (336.08, 161.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1155)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 296, 698)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1696)
[M::mem_pestat] mean and std.dev: (353.73, 221.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2195)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (21, 278407, 9, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (142, 151, 475)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1141)
[M::mem_pestat] mean and std.dev: (277.71, 239.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1474)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 319, 445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 921)
[M::mem_pestat] mean and std.dev: (336.91, 162.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1159)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 223, 407)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 807)
[M::mem_pestat] mean and std.dev: (280.54, 125.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1007)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 684428 reads in 627.572 CPU sec, 21.186 real sec
[M::mem_process_seqs] Processed 683970 reads in 383.941 CPU sec, 13.379 real sec
[M::mem_process_seqs] Processed 684208 reads in 406.561 CPU sec, 14.144 real sec
sorting block 0, #reads = 1070255 mem = 536877685 peak = 595451904
[M::process] read 683658 sequences (100000278 bp) in 3.719 CPU sec, 4.601 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 278989, 12, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 357, 450)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1048)
[M::mem_pestat] mean and std.dev: (284.22, 154.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1347)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 320, 445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 919)
[M::mem_pestat] mean and std.dev: (336.96, 161.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1156)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (555, 1078, 1078)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2124)
[M::mem_pestat] mean and std.dev: (742.33, 463.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2647)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 238, 345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 727)
[M::mem_pestat] mean and std.dev: (235.49, 117.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 918)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 683506 sequences (100000024 bp) in 4.331 CPU sec, 4.556 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 278099, 3, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 327, 537)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1225)
[M::mem_pestat] mean and std.dev: (338.60, 159.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1569)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 324, 452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 936)
[M::mem_pestat] mean and std.dev: (341.38, 163.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1178)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 264, 479)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1119)
[M::mem_pestat] mean and std.dev: (296.00, 196.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1439)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682930 sequences (100000117 bp) in 2.095 CPU sec, 2.102 real sec...
[M::mem_process_seqs] Processed 683880 reads in 369.947 CPU sec, 11.913 real sec
sorting block 1, #reads = 1071110 mem = 536880254 peak = 862838784
[M::mem_process_seqs] Processed 683658 reads in 193.702 CPU sec, 6.156 real sec
sorting block 2, #reads = 1070385 mem = 536877968 peak = 950333440
[M::process] read 684204 sequences (100000033 bp) in 2.771 CPU sec, 2.941 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 278329, 8, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 231, 455)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1031)
[M::mem_pestat] mean and std.dev: (295.72, 185.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1319)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 325, 452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 936)
[M::mem_pestat] mean and std.dev: (341.49, 163.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1178)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 297, 395)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 767)
[M::mem_pestat] mean and std.dev: (294.10, 154.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 953)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681920 sequences (100000003 bp) in 1.908 CPU sec, 1.972 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 277764, 12, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 276, 581)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1363)
[M::mem_pestat] mean and std.dev: (319.66, 204.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1754)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 329, 459)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 953)
[M::mem_pestat] mean and std.dev: (345.84, 165.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1200)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (117, 280, 543)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1395)
[M::mem_pestat] mean and std.dev: (370.17, 355.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1821)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (243, 295, 465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 909)
[M::mem_pestat] mean and std.dev: (308.29, 109.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1131)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683506 reads in 248.686 CPU sec, 7.965 real sec
[M::mem_process_seqs] Processed 682930 reads in 152.060 CPU sec, 4.871 real sec
sorting block 3, #reads = 1069782 mem = 536879892 peak = 950333440
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 279188, 9, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 244, 369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 777)
[M::mem_pestat] mean and std.dev: (279.72, 133.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 981)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 317, 449)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 937)
[M::mem_pestat] mean and std.dev: (337.56, 164.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1181)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 255, 501)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1163)
[M::mem_pestat] mean and std.dev: (330.93, 220.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1494)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681496 sequences (100000146 bp) in 2.937 CPU sec, 3.111 real sec...
[M::process] read 681204 sequences (100000281 bp) in 2.592 CPU sec, 2.607 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 277678, 11, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 317, 721)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1861)
[M::mem_pestat] mean and std.dev: (454.46, 423.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2431)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 335, 465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 961)
[M::mem_pestat] mean and std.dev: (351.03, 167.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1209)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (83, 133, 749)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2081)
[M::mem_pestat] mean and std.dev: (298.70, 283.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2747)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 310, 1913)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5345)
[M::mem_pestat] mean and std.dev: (1315.41, 1827.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8626)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 684204 reads in 253.337 CPU sec, 8.075 real sec
[M::mem_process_seqs] Processed 681920 reads in 171.635 CPU sec, 5.462 real sec
sorting block 4, #reads = 1069103 mem = 536877926 peak = 950333440
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 277309, 5, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 246, 1227)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3257)
[M::mem_pestat] mean and std.dev: (687.18, 783.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4272)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 338, 468)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 966)
[M::mem_pestat] mean and std.dev: (353.81, 167.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1215)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (275, 315, 543)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1079)
[M::mem_pestat] mean and std.dev: (401.04, 190.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1347)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680902 sequences (100000161 bp) in 3.135 CPU sec, 3.391 real sec...
[M::process] read 680960 sequences (100000250 bp) in 2.172 CPU sec, 2.182 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 277181, 9, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 304, 661)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1663)
[M::mem_pestat] mean and std.dev: (379.55, 256.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2164)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 339, 468)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 964)
[M::mem_pestat] mean and std.dev: (354.40, 167.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1212)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (231, 280, 432)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 834)
[M::mem_pestat] mean and std.dev: (309.02, 124.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1035)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681496 reads in 248.044 CPU sec, 7.917 real sec
sorting block 5, #reads = 1068852 mem = 536878596 peak = 950333440
[M::mem_process_seqs] Processed 681204 reads in 155.839 CPU sec, 4.956 real sec
sorting block 6, #reads = 1069086 mem = 536880188 peak = 950333440
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (16, 277060, 18, 21)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 268, 648)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1626)
[M::mem_pestat] mean and std.dev: (317.43, 238.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2115)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 344, 474)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 974)
[M::mem_pestat] mean and std.dev: (358.43, 169.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1224)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (68, 549, 549)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1511)
[M::mem_pestat] mean and std.dev: (289.67, 242.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1992)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 208, 441)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 965)
[M::mem_pestat] mean and std.dev: (291.43, 149.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1227)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 680962 sequences (100000172 bp) in 3.247 CPU sec, 3.456 real sec...
[M::process] read 681394 sequences (100000007 bp) in 2.722 CPU sec, 2.723 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 277342, 15, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (258, 436, 496)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 972)
[M::mem_pestat] mean and std.dev: (355.82, 145.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1210)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 342, 472)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 972)
[M::mem_pestat] mean and std.dev: (356.67, 168.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1222)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (574, 861, 4037)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10963)
[M::mem_pestat] mean and std.dev: (1754.27, 1867.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14426)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (265, 280, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (121, 481)
[M::mem_pestat] mean and std.dev: (278.91, 57.93)
[M::mem_pestat] low and high boundaries for proper pairs: (47, 553)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680902 reads in 244.855 CPU sec, 7.788 real sec
[M::mem_process_seqs] Processed 680960 reads in 155.053 CPU sec, 4.920 real sec
sorting block 7, #reads = 1069021 mem = 536881398 peak = 950333440
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 277263, 16, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 253, 423)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 909)
[M::mem_pestat] mean and std.dev: (269.75, 119.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1152)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 341, 470)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 966)
[M::mem_pestat] mean and std.dev: (356.12, 167.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1214)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (275, 678, 2009)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5477)
[M::mem_pestat] mean and std.dev: (1042.50, 835.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7211)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 222, 320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 610)
[M::mem_pestat] mean and std.dev: (208.90, 81.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 755)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 681526 sequences (100000263 bp) in 3.065 CPU sec, 3.304 real sec...
[M::process] read 679920 sequences (100000212 bp) in 1.909 CPU sec, 1.924 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 276722, 16, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 459, 487)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1039)
[M::mem_pestat] mean and std.dev: (359.97, 234.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1315)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 337, 463)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 949)
[M::mem_pestat] mean and std.dev: (351.84, 165.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1192)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (386, 1974, 2651)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7181)
[M::mem_pestat] mean and std.dev: (1765.69, 1156.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9446)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 288, 505)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1085)
[M::mem_pestat] mean and std.dev: (338.29, 227.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1375)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680962 reads in 245.750 CPU sec, 7.879 real sec
[M::mem_process_seqs] Processed 681394 reads in 156.712 CPU sec, 5.005 real sec
sorting block 8, #reads = 1069504 mem = 536880120 peak = 950333440
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 277337, 7, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 279, 469)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1023)
[M::mem_pestat] mean and std.dev: (307.16, 184.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1300)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 334, 463)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 953)
[M::mem_pestat] mean and std.dev: (350.53, 166.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1198)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (258, 313, 606)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1302)
[M::mem_pestat] mean and std.dev: (343.34, 246.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1650)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 679748 sequences (100000281 bp) in 3.444 CPU sec, 4.010 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 276833, 15, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (335, 430, 787)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1691)
[M::mem_pestat] mean and std.dev: (433.91, 242.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2143)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 340, 468)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 954)
[M::mem_pestat] mean and std.dev: (355.79, 165.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1197)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (543, 594, 2001)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4917)
[M::mem_pestat] mean and std.dev: (965.13, 940.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6375)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (143, 225, 515)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1259)
[M::mem_pestat] mean and std.dev: (235.80, 154.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1631)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 680260 sequences (100000204 bp) in 2.250 CPU sec, 2.250 real sec...
[M::mem_process_seqs] Processed 681526 reads in 246.664 CPU sec, 7.915 real sec
[M::mem_process_seqs] Processed 679920 reads in 155.795 CPU sec, 4.967 real sec
sorting block 9, #reads = 1068291 mem = 536880383 peak = 950333440
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 276660, 13, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 307, 385)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 781)
[M::mem_pestat] mean and std.dev: (303.02, 153.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 979)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 345, 473)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 965)
[M::mem_pestat] mean and std.dev: (359.36, 167.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1211)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (50, 451, 3714)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 11042)
[M::mem_pestat] mean and std.dev: (1781.77, 1792.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14706)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 218, 320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 642)
[M::mem_pestat] mean and std.dev: (220.40, 78.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 803)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 679586 sequences (100000113 bp) in 2.969 CPU sec, 3.333 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 276718, 7, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (139, 207, 377)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 853)
[M::mem_pestat] mean and std.dev: (224.92, 121.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1091)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 345, 473)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 967)
[M::mem_pestat] mean and std.dev: (359.27, 167.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1214)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 385, 446)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 898)
[M::mem_pestat] mean and std.dev: (353.86, 167.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1124)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 679400 sequences (100000254 bp) in 2.547 CPU sec, 2.551 real sec...
[M::mem_process_seqs] Processed 679748 reads in 240.412 CPU sec, 7.711 real sec
sorting block 10, #reads = 1067694 mem = 536879219 peak = 950333440
[M::mem_process_seqs] Processed 680260 reads in 153.972 CPU sec, 4.896 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 276482, 7, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 227, 349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 699)
[M::mem_pestat] mean and std.dev: (245.81, 109.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 874)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 345, 472)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 960)
[M::mem_pestat] mean and std.dev: (359.03, 165.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1204)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 331, 1038)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2664)
[M::mem_pestat] mean and std.dev: (560.02, 471.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3477)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 11, #reads = 1068265 mem = 536882385 peak = 950333440
[M::process] read 679888 sequences (100000221 bp) in 3.728 CPU sec, 4.024 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 276723, 12, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 299, 1691)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4635)
[M::mem_pestat] mean and std.dev: (881.65, 1122.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6107)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 344, 468)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 948)
[M::mem_pestat] mean and std.dev: (357.42, 164.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1188)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (109, 901, 5417)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 16033)
[M::mem_pestat] mean and std.dev: (1724.17, 2165.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 21341)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (247, 307, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (25, 580)
[M::mem_pestat] mean and std.dev: (283.46, 88.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 691)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 679844 sequences (100000254 bp) in 2.490 CPU sec, 2.499 real sec...
[M::mem_process_seqs] Processed 679586 reads in 238.645 CPU sec, 7.626 real sec
[M::mem_process_seqs] Processed 679400 reads in 158.161 CPU sec, 5.011 real sec
sorting block 12, #reads = 1068989 mem = 536879959 peak = 950333440
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 276993, 11, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 219, 647)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1591)
[M::mem_pestat] mean and std.dev: (373.33, 290.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2063)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 343, 469)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 955)
[M::mem_pestat] mean and std.dev: (357.24, 165.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1198)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1420, 1907, 3182)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6706)
[M::mem_pestat] mean and std.dev: (1768.55, 1158.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8468)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 286, 451)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 937)
[M::mem_pestat] mean and std.dev: (286.68, 134.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1180)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 679956 sequences (100000200 bp) in 3.100 CPU sec, 3.511 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 276944, 8, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 217, 454)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1024)
[M::mem_pestat] mean and std.dev: (320.74, 182.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1309)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 342, 468)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 952)
[M::mem_pestat] mean and std.dev: (356.75, 165.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1194)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 202, 440)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 992)
[M::mem_pestat] mean and std.dev: (279.94, 172.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1268)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680080 sequences (100000183 bp) in 2.400 CPU sec, 2.403 real sec...
[M::mem_process_seqs] Processed 679888 reads in 246.410 CPU sec, 7.920 real sec
[M::mem_process_seqs] Processed 679844 reads in 159.958 CPU sec, 5.105 real sec
sorting block 13, #reads = 1067832 mem = 536886041 peak = 950333440
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 276515, 8, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 271, 633)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1597)
[M::mem_pestat] mean and std.dev: (332.89, 241.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2079)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 340, 467)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 951)
[M::mem_pestat] mean and std.dev: (355.65, 165.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1193)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (263, 356, 694)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1556)
[M::mem_pestat] mean and std.dev: (340.67, 219.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1987)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680058 sequences (100000045 bp) in 4.006 CPU sec, 4.329 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 276740, 9, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 213, 432)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 962)
[M::mem_pestat] mean and std.dev: (269.84, 132.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1227)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 340, 464)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 942)
[M::mem_pestat] mean and std.dev: (354.07, 164.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1181)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (236, 311, 486)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 986)
[M::mem_pestat] mean and std.dev: (309.30, 132.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1236)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 679956 reads in 237.314 CPU sec, 7.591 real sec
[M::process] read 679568 sequences (100000069 bp) in 2.174 CPU sec, 2.216 real sec...
sorting block 14, #reads = 1066978 mem = 536878875 peak = 950333440
[M::mem_process_seqs] Processed 680080 reads in 154.485 CPU sec, 4.922 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 276692, 8, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (127, 204, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 775)
[M::mem_pestat] mean and std.dev: (233.39, 125.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 991)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 339, 464)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 942)
[M::mem_pestat] mean and std.dev: (353.83, 164.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1181)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 260, 397)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 843)
[M::mem_pestat] mean and std.dev: (266.82, 121.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1066)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 679342 sequences (100000071 bp) in 2.936 CPU sec, 3.629 real sec...
sorting block 15, #reads = 1067975 mem = 536881723 peak = 950333440
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 276877, 4, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (241, 430, 1111)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2851)
[M::mem_pestat] mean and std.dev: (504.03, 381.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3721)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 344, 471)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 957)
[M::mem_pestat] mean and std.dev: (358.54, 166.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1200)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (241, 326, 587)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1279)
[M::mem_pestat] mean and std.dev: (401.14, 202.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1625)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680058 reads in 231.457 CPU sec, 7.507 real sec
[M::process] read 679274 sequences (100000128 bp) in 2.816 CPU sec, 2.915 real sec...
[M::mem_process_seqs] Processed 679568 reads in 150.148 CPU sec, 4.822 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 276962, 8, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 259, 271)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (31, 431)
[M::mem_pestat] mean and std.dev: (236.56, 72.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 527)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 344, 470)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 952)
[M::mem_pestat] mean and std.dev: (359.16, 166.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1193)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 327, 499)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1081)
[M::mem_pestat] mean and std.dev: (268.42, 105.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1372)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 16, #reads = 1067560 mem = 536880341 peak = 950333440
[M::process] read 678896 sequences (100000074 bp) in 3.538 CPU sec, 3.838 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 276540, 3, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 296, 489)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1113)
[M::mem_pestat] mean and std.dev: (301.48, 202.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1425)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 345, 471)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 955)
[M::mem_pestat] mean and std.dev: (359.58, 166.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1197)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 363, 419)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 887)
[M::mem_pestat] mean and std.dev: (316.60, 159.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1121)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 679342 reads in 227.491 CPU sec, 7.288 real sec
[M::process] read 679862 sequences (100000197 bp) in 2.465 CPU sec, 2.489 real sec...
[M::mem_process_seqs] Processed 679274 reads in 147.942 CPU sec, 4.684 real sec
sorting block 17, #reads = 1067268 mem = 536876889 peak = 950333440
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 276890, 7, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (127, 288, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 841)
[M::mem_pestat] mean and std.dev: (268.30, 146.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1079)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (231, 348, 474)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 960)
[M::mem_pestat] mean and std.dev: (362.55, 168.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1203)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 243, 276)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 462)
[M::mem_pestat] mean and std.dev: (237.93, 80.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 558)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 684414 sequences (100000000 bp) in 2.839 CPU sec, 3.102 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 277145, 19, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 254, 423)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 953)
[M::mem_pestat] mean and std.dev: (257.90, 124.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1218)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 346, 472)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 962)
[M::mem_pestat] mean and std.dev: (360.00, 168.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1207)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1023, 1023, 3223)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7623)
[M::mem_pestat] mean and std.dev: (1695.32, 1030.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9823)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (297, 438, 782)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1752)
[M::mem_pestat] mean and std.dev: (498.02, 286.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2237)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 683630 sequences (100000183 bp) in 2.409 CPU sec, 2.448 real sec...
[M::mem_process_seqs] Processed 678896 reads in 232.629 CPU sec, 7.455 real sec
[M::mem_process_seqs] Processed 679862 reads in 154.505 CPU sec, 4.908 real sec
sorting block 18, #reads = 1069007 mem = 536879890 peak = 950333440
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 277915, 8, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (299, 420, 695)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1487)
[M::mem_pestat] mean and std.dev: (394.03, 168.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1883)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 318, 449)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 937)
[M::mem_pestat] mean and std.dev: (337.64, 164.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1181)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 281, 398)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 904)
[M::mem_pestat] mean and std.dev: (276.44, 148.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1157)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 683508 sequences (100000247 bp) in 3.885 CPU sec, 4.377 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 278267, 7, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 224, 257)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (101, 361)
[M::mem_pestat] mean and std.dev: (208.29, 49.46)
[M::mem_pestat] low and high boundaries for proper pairs: (10, 413)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 322, 450)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 934)
[M::mem_pestat] mean and std.dev: (340.05, 164.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1176)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 290, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 587)
[M::mem_pestat] mean and std.dev: (262.55, 84.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 710)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 683602 sequences (100000296 bp) in 2.356 CPU sec, 2.358 real sec...
[M::mem_process_seqs] Processed 684414 reads in 237.973 CPU sec, 7.609 real sec
sorting block 19, #reads = 1067303 mem = 536878742 peak = 950333440
[M::mem_process_seqs] Processed 683630 reads in 148.864 CPU sec, 4.731 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 278098, 7, 24)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 279, 569)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1325)
[M::mem_pestat] mean and std.dev: (342.97, 288.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1703)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 325, 455)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 947)
[M::mem_pestat] mean and std.dev: (342.68, 165.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1193)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 449, 455)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 953)
[M::mem_pestat] mean and std.dev: (349.86, 166.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1202)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 20, #reads = 1071133 mem = 536879370 peak = 950333440
[M::process] read 683092 sequences (100000063 bp) in 3.307 CPU sec, 3.697 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 278070, 10, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 276, 280)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 472)
[M::mem_pestat] mean and std.dev: (242.27, 75.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 568)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 324, 453)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 941)
[M::mem_pestat] mean and std.dev: (341.77, 164.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1185)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 428, 1071)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2883)
[M::mem_pestat] mean and std.dev: (510.33, 480.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3789)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (231, 289, 350)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 588)
[M::mem_pestat] mean and std.dev: (265.81, 66.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 707)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682846 sequences (100000050 bp) in 2.349 CPU sec, 2.355 real sec...
[M::mem_process_seqs] Processed 683508 reads in 237.536 CPU sec, 7.597 real sec
[M::mem_process_seqs] Processed 683602 reads in 155.208 CPU sec, 4.919 real sec
sorting block 21, #reads = 1070673 mem = 536881714 peak = 950333440
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (14, 277498, 18, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (141, 189, 267)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 519)
[M::mem_pestat] mean and std.dev: (187.79, 65.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 645)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 328, 456)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 946)
[M::mem_pestat] mean and std.dev: (344.14, 165.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1191)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (441, 877, 1232)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2814)
[M::mem_pestat] mean and std.dev: (729.19, 353.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3605)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 353, 596)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1370)
[M::mem_pestat] mean and std.dev: (378.11, 214.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1757)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682572 sequences (100000022 bp) in 3.726 CPU sec, 4.191 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 277944, 4, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 206, 481)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1127)
[M::mem_pestat] mean and std.dev: (322.23, 231.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1450)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 330, 459)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 951)
[M::mem_pestat] mean and std.dev: (345.89, 165.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1197)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 349, 446)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 960)
[M::mem_pestat] mean and std.dev: (287.31, 130.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1217)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683092 reads in 240.240 CPU sec, 7.695 real sec
[M::process] read 682486 sequences (100000162 bp) in 2.857 CPU sec, 2.909 real sec...
[M::mem_process_seqs] Processed 682846 reads in 158.900 CPU sec, 5.050 real sec
sorting block 22, #reads = 1070392 mem = 536884429 peak = 950333440
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 277441, 8, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 304, 459)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 939)
[M::mem_pestat] mean and std.dev: (284.04, 141.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1179)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 332, 461)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 955)
[M::mem_pestat] mean and std.dev: (347.57, 165.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1202)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (241, 259, 371)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 631)
[M::mem_pestat] mean and std.dev: (259.06, 65.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 761)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681848 sequences (100000189 bp) in 3.171 CPU sec, 3.683 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 278031, 8, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (142, 258, 448)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1060)
[M::mem_pestat] mean and std.dev: (242.56, 130.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1366)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 334, 465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 965)
[M::mem_pestat] mean and std.dev: (350.23, 168.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1215)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 248, 403)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 841)
[M::mem_pestat] mean and std.dev: (275.90, 124.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1060)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682572 reads in 232.449 CPU sec, 7.498 real sec
[M::mem_process_seqs] Processed 682486 reads in 153.209 CPU sec, 4.886 real sec
[M::process] read 681410 sequences (100000015 bp) in 2.415 CPU sec, 2.506 real sec...
sorting block 23, #reads = 1070965 mem = 536878504 peak = 950333440
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 276842, 4, 24)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 332, 424)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 828)
[M::mem_pestat] mean and std.dev: (328.49, 157.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1030)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 339, 471)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 977)
[M::mem_pestat] mean and std.dev: (354.36, 169.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1230)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 365, 507)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1165)
[M::mem_pestat] mean and std.dev: (374.17, 248.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1494)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680962 sequences (100000300 bp) in 3.668 CPU sec, 4.071 real sec...
sorting block 24, #reads = 1069774 mem = 536878187 peak = 950333440
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 276899, 9, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 299, 412)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 792)
[M::mem_pestat] mean and std.dev: (274.03, 117.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 982)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 343, 474)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 980)
[M::mem_pestat] mean and std.dev: (357.08, 169.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1233)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (264, 413, 547)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1113)
[M::mem_pestat] mean and std.dev: (388.28, 187.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1396)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681848 reads in 238.021 CPU sec, 7.626 real sec
[M::process] read 680594 sequences (100000241 bp) in 2.304 CPU sec, 2.312 real sec...
[M::mem_process_seqs] Processed 681410 reads in 152.588 CPU sec, 4.840 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 277445, 8, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (258, 366, 619)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1341)
[M::mem_pestat] mean and std.dev: (392.38, 235.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1702)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 346, 478)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 986)
[M::mem_pestat] mean and std.dev: (360.60, 170.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1240)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 280, 356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 802)
[M::mem_pestat] mean and std.dev: (288.19, 150.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1025)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 25, #reads = 1069467 mem = 536877357 peak = 950333440
[M::process] read 680816 sequences (100000251 bp) in 3.362 CPU sec, 3.688 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 276513, 7, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 280, 898)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2342)
[M::mem_pestat] mean and std.dev: (358.63, 279.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3064)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 347, 478)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 984)
[M::mem_pestat] mean and std.dev: (361.29, 170.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1237)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 244, 457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 929)
[M::mem_pestat] mean and std.dev: (313.77, 180.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1165)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680962 reads in 237.901 CPU sec, 7.602 real sec
[M::process] read 680650 sequences (100000232 bp) in 2.469 CPU sec, 2.504 real sec...
[M::mem_process_seqs] Processed 680594 reads in 156.794 CPU sec, 4.974 real sec
sorting block 26, #reads = 1068865 mem = 536879423 peak = 950333440
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (22, 276897, 7, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 190, 353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 763)
[M::mem_pestat] mean and std.dev: (257.18, 140.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 968)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 345, 475)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 977)
[M::mem_pestat] mean and std.dev: (359.45, 169.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1228)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 222, 349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 719)
[M::mem_pestat] mean and std.dev: (268.33, 128.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 904)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680438 sequences (100000006 bp) in 3.701 CPU sec, 4.148 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 277098, 11, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (131, 167, 221)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 401)
[M::mem_pestat] mean and std.dev: (177.10, 72.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 491)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 347, 476)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 976)
[M::mem_pestat] mean and std.dev: (360.26, 168.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1226)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (42, 361, 3710)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 11046)
[M::mem_pestat] mean and std.dev: (1132.64, 1583.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14714)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 324, 377)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 693)
[M::mem_pestat] mean and std.dev: (341.73, 164.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1001)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 680402 sequences (100000115 bp) in 2.414 CPU sec, 2.423 real sec...
[M::mem_process_seqs] Processed 680816 reads in 236.761 CPU sec, 7.570 real sec
[M::mem_process_seqs] Processed 680650 reads in 154.812 CPU sec, 4.924 real sec
sorting block 27, #reads = 1068284 mem = 536880326 peak = 950333440
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 276845, 15, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 272, 393)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 787)
[M::mem_pestat] mean and std.dev: (255.03, 125.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 984)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 347, 474)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 970)
[M::mem_pestat] mean and std.dev: (360.08, 167.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1218)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (115, 115, 2543)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7399)
[M::mem_pestat] mean and std.dev: (916.87, 1068.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9827)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 367, 578)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1292)
[M::mem_pestat] mean and std.dev: (373.97, 210.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1649)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 680042 sequences (100000298 bp) in 3.131 CPU sec, 3.683 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 277237, 12, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 257, 1200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3276)
[M::mem_pestat] mean and std.dev: (486.22, 463.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4314)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 343, 470)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 962)
[M::mem_pestat] mean and std.dev: (356.70, 166.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1208)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (328, 576, 737)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1555)
[M::mem_pestat] mean and std.dev: (581.08, 363.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2036)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 337, 416)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 806)
[M::mem_pestat] mean and std.dev: (297.68, 146.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1001)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 679848 sequences (100000270 bp) in 2.095 CPU sec, 2.106 real sec...
[M::mem_process_seqs] Processed 680438 reads in 234.608 CPU sec, 7.595 real sec
sorting block 28, #reads = 1069281 mem = 536878435 peak = 950333440
[M::mem_process_seqs] Processed 680402 reads in 152.149 CPU sec, 4.919 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 276240, 8, 20)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 197, 374)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 786)
[M::mem_pestat] mean and std.dev: (211.30, 91.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 992)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 346, 474)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 966)
[M::mem_pestat] mean and std.dev: (359.84, 167.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1212)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (278, 355, 509)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 971)
[M::mem_pestat] mean and std.dev: (346.06, 131.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1202)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 679942 sequences (100000236 bp) in 3.564 CPU sec, 4.161 real sec...
sorting block 29, #reads = 1069170 mem = 536879423 peak = 983416832
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 276907, 6, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 291, 478)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1128)
[M::mem_pestat] mean and std.dev: (281.25, 150.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1453)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 349, 475)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 967)
[M::mem_pestat] mean and std.dev: (361.80, 167.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1213)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 185, 264)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 486)
[M::mem_pestat] mean and std.dev: (198.48, 70.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 597)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680042 reads in 233.721 CPU sec, 7.564 real sec
[M::process] read 679704 sequences (100000181 bp) in 2.260 CPU sec, 2.354 real sec...
[M::mem_process_seqs] Processed 679848 reads in 151.932 CPU sec, 4.878 real sec
sorting block 30, #reads = 1068305 mem = 536877144 peak = 983416832
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 276714, 18, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 263, 301)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (13, 493)
[M::mem_pestat] mean and std.dev: (240.79, 61.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 589)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 345, 471)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 959)
[M::mem_pestat] mean and std.dev: (358.25, 165.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1203)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (117, 221, 538)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1380)
[M::mem_pestat] mean and std.dev: (291.83, 227.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1801)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 222, 458)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 960)
[M::mem_pestat] mean and std.dev: (297.32, 145.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1211)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 679606 sequences (100000124 bp) in 3.192 CPU sec, 3.562 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 277238, 11, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (223, 351, 895)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2239)
[M::mem_pestat] mean and std.dev: (603.57, 610.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3045)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 348, 476)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 970)
[M::mem_pestat] mean and std.dev: (361.95, 167.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1217)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (241, 663, 1740)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4738)
[M::mem_pestat] mean and std.dev: (852.73, 663.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6237)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 220, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 631)
[M::mem_pestat] mean and std.dev: (241.87, 119.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 786)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 679942 reads in 229.907 CPU sec, 7.417 real sec
[M::process] read 679386 sequences (100000124 bp) in 2.149 CPU sec, 2.342 real sec...
[M::mem_process_seqs] Processed 679704 reads in 159.898 CPU sec, 5.118 real sec
sorting block 31, #reads = 1068345 mem = 536877927 peak = 983416832
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 276553, 10, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 269, 301)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (7, 497)
[M::mem_pestat] mean and std.dev: (245.21, 71.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 595)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 346, 471)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 955)
[M::mem_pestat] mean and std.dev: (359.16, 165.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1197)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (23, 351, 858)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2528)
[M::mem_pestat] mean and std.dev: (301.00, 304.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3363)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 230, 384)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 814)
[M::mem_pestat] mean and std.dev: (270.37, 140.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1029)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 680000 sequences (100000122 bp) in 3.416 CPU sec, 3.903 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 276171, 5, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (139, 180, 450)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1072)
[M::mem_pestat] mean and std.dev: (269.57, 198.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1383)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 345, 469)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 951)
[M::mem_pestat] mean and std.dev: (358.11, 164.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1192)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (277, 383, 527)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1027)
[M::mem_pestat] mean and std.dev: (356.07, 111.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1277)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 679606 reads in 238.743 CPU sec, 7.735 real sec
[M::mem_process_seqs] Processed 679386 reads in 156.831 CPU sec, 5.004 real sec
sorting block 32, #reads = 1067627 mem = 536879036 peak = 983416832
[M::process] read 680186 sequences (100000155 bp) in 2.832 CPU sec, 2.981 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 276517, 6, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 204, 251)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 455)
[M::mem_pestat] mean and std.dev: (179.12, 66.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 557)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 342, 466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 946)
[M::mem_pestat] mean and std.dev: (355.59, 164.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1186)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 309, 508)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1084)
[M::mem_pestat] mean and std.dev: (332.84, 157.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1372)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 679994 sequences (100000262 bp) in 3.402 CPU sec, 3.933 real sec...
sorting block 33, #reads = 1067068 mem = 536879488 peak = 983416832
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 277017, 6, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 391, 1259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3337)
[M::mem_pestat] mean and std.dev: (600.00, 500.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4376)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 341, 467)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 951)
[M::mem_pestat] mean and std.dev: (355.35, 164.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1193)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 217, 405)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 845)
[M::mem_pestat] mean and std.dev: (258.23, 99.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1065)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680000 reads in 229.988 CPU sec, 7.405 real sec
[M::mem_process_seqs] Processed 680186 reads in 151.564 CPU sec, 4.816 real sec
[M::process] read 680184 sequences (100000121 bp) in 3.012 CPU sec, 3.186 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 276917, 8, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 239, 507)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1203)
[M::mem_pestat] mean and std.dev: (294.23, 167.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1551)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 342, 466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 946)
[M::mem_pestat] mean and std.dev: (356.06, 165.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1186)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 207, 426)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 948)
[M::mem_pestat] mean and std.dev: (315.11, 214.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1209)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 34, #reads = 1066231 mem = 536878712 peak = 983416832
[M::process] read 680024 sequences (100000078 bp) in 3.308 CPU sec, 3.806 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 276798, 12, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (234, 391, 1474)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3954)
[M::mem_pestat] mean and std.dev: (626.31, 533.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5194)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 341, 466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 948)
[M::mem_pestat] mean and std.dev: (355.21, 165.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1189)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (390, 1157, 1473)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3639)
[M::mem_pestat] mean and std.dev: (923.08, 508.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4722)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 269, 426)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 900)
[M::mem_pestat] mean and std.dev: (294.07, 138.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1137)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 679994 reads in 239.789 CPU sec, 7.723 real sec
[M::mem_process_seqs] Processed 680184 reads in 160.767 CPU sec, 5.125 real sec
[M::process] read 679824 sequences (100000119 bp) in 2.790 CPU sec, 2.982 real sec...
sorting block 35, #reads = 1068213 mem = 536879331 peak = 983416832
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 277321, 13, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 199, 507)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1201)
[M::mem_pestat] mean and std.dev: (336.33, 271.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1548)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 341, 465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 943)
[M::mem_pestat] mean and std.dev: (355.06, 164.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1182)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 559, 1515)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4217)
[M::mem_pestat] mean and std.dev: (652.33, 563.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5568)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 244, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 665)
[M::mem_pestat] mean and std.dev: (266.16, 113.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 829)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 680022 sequences (100000264 bp) in 3.326 CPU sec, 3.688 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 276604, 9, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 248, 422)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 876)
[M::mem_pestat] mean and std.dev: (307.72, 182.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1103)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 343, 468)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 950)
[M::mem_pestat] mean and std.dev: (357.41, 166.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1191)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (231, 309, 1259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3315)
[M::mem_pestat] mean and std.dev: (504.05, 474.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4343)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680024 reads in 236.863 CPU sec, 7.604 real sec
[M::process] read 679458 sequences (100000020 bp) in 2.983 CPU sec, 3.117 real sec...
[M::mem_process_seqs] Processed 679824 reads in 156.715 CPU sec, 4.981 real sec
sorting block 36, #reads = 1067336 mem = 536877298 peak = 983416832
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 277085, 7, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 297, 444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 954)
[M::mem_pestat] mean and std.dev: (327.10, 199.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1209)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 340, 466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 948)
[M::mem_pestat] mean and std.dev: (355.77, 166.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1189)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 251, 374)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 750)
[M::mem_pestat] mean and std.dev: (235.81, 103.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 938)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 679602 sequences (100000134 bp) in 3.099 CPU sec, 3.694 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 277231, 12, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (134, 207, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 740)
[M::mem_pestat] mean and std.dev: (232.03, 118.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 942)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 348, 476)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 970)
[M::mem_pestat] mean and std.dev: (362.72, 169.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1217)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (971, 1358, 1914)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3800)
[M::mem_pestat] mean and std.dev: (1415.83, 840.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4779)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 312, 400)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 784)
[M::mem_pestat] mean and std.dev: (296.80, 102.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 976)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680022 reads in 237.453 CPU sec, 7.642 real sec
[M::process] read 684870 sequences (100000164 bp) in 2.320 CPU sec, 2.331 real sec...
sorting block 37, #reads = 1066847 mem = 536879043 peak = 983416832
[M::mem_process_seqs] Processed 679458 reads in 162.179 CPU sec, 5.177 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 277518, 16, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 262, 452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 982)
[M::mem_pestat] mean and std.dev: (314.76, 144.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1247)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 348, 476)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 972)
[M::mem_pestat] mean and std.dev: (362.24, 169.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1220)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (11, 270, 3118)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9332)
[M::mem_pestat] mean and std.dev: (399.54, 839.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12439)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 259, 461)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 989)
[M::mem_pestat] mean and std.dev: (321.21, 182.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1253)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 38, #reads = 1066022 mem = 536878780 peak = 1005694976
[M::process] read 684138 sequences (100000211 bp) in 2.960 CPU sec, 3.397 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 279080, 4, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 267, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 591)
[M::mem_pestat] mean and std.dev: (275.37, 93.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 715)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 317, 447)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 933)
[M::mem_pestat] mean and std.dev: (336.33, 164.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1176)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 251, 347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 713)
[M::mem_pestat] mean and std.dev: (258.22, 114.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 896)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 683958 sequences (100000061 bp) in 2.574 CPU sec, 2.730 real sec...
[M::mem_process_seqs] Processed 679602 reads in 232.931 CPU sec, 7.466 real sec
[M::mem_process_seqs] Processed 684870 reads in 153.832 CPU sec, 4.891 real sec
sorting block 39, #reads = 1068983 mem = 536876325 peak = 1005694976
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 278645, 10, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (116, 249, 401)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 971)
[M::mem_pestat] mean and std.dev: (265.62, 153.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1256)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 320, 450)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 938)
[M::mem_pestat] mean and std.dev: (339.03, 164.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1182)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (497, 5840, 5840)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 16526)
[M::mem_pestat] mean and std.dev: (3356.50, 2742.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 21869)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 274, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 630)
[M::mem_pestat] mean and std.dev: (264.91, 75.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 764)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 683670 sequences (100000040 bp) in 3.217 CPU sec, 3.655 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (22, 279208, 9, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 215, 477)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1087)
[M::mem_pestat] mean and std.dev: (302.75, 212.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1392)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 324, 454)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 946)
[M::mem_pestat] mean and std.dev: (341.55, 165.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1192)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 287, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (10, 530)
[M::mem_pestat] mean and std.dev: (258.91, 77.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 634)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 684138 reads in 237.808 CPU sec, 7.634 real sec
[M::process] read 683300 sequences (100000256 bp) in 2.750 CPU sec, 2.777 real sec...
[M::mem_process_seqs] Processed 683958 reads in 151.553 CPU sec, 4.834 real sec
sorting block 40, #reads = 1069574 mem = 536885272 peak = 1005694976
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (22, 278162, 13, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (230, 250, 295)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (100, 425)
[M::mem_pestat] mean and std.dev: (244.37, 54.67)
[M::mem_pestat] low and high boundaries for proper pairs: (26, 490)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 324, 452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 936)
[M::mem_pestat] mean and std.dev: (341.52, 163.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1178)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 233, 1665)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4657)
[M::mem_pestat] mean and std.dev: (734.67, 782.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6153)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 302, 518)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1156)
[M::mem_pestat] mean and std.dev: (367.10, 246.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1475)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 683224 sequences (100000275 bp) in 3.498 CPU sec, 3.867 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 278691, 7, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (240, 298, 662)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1506)
[M::mem_pestat] mean and std.dev: (400.62, 247.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1928)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 326, 453)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 937)
[M::mem_pestat] mean and std.dev: (342.20, 163.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1179)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 285, 444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 984)
[M::mem_pestat] mean and std.dev: (300.34, 152.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1254)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682724 sequences (100000104 bp) in 2.333 CPU sec, 2.406 real sec...
[M::mem_process_seqs] Processed 683670 reads in 236.735 CPU sec, 7.588 real sec
[M::mem_process_seqs] Processed 683300 reads in 149.939 CPU sec, 4.773 real sec
sorting block 41, #reads = 1070179 mem = 536881095 peak = 1005694976
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 278292, 8, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 315, 818)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2026)
[M::mem_pestat] mean and std.dev: (403.64, 270.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2630)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 328, 455)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 941)
[M::mem_pestat] mean and std.dev: (343.80, 164.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1184)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 289, 471)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 975)
[M::mem_pestat] mean and std.dev: (287.47, 114.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1227)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682322 sequences (100000268 bp) in 3.328 CPU sec, 3.934 real sec...
sorting block 42, #reads = 1070159 mem = 536879003 peak = 1005694976
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 277729, 7, 23)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 215, 378)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 834)
[M::mem_pestat] mean and std.dev: (239.33, 129.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1062)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 331, 458)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 946)
[M::mem_pestat] mean and std.dev: (346.07, 164.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1190)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 262, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 654)
[M::mem_pestat] mean and std.dev: (239.61, 71.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 801)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683224 reads in 235.487 CPU sec, 7.600 real sec
[M::process] read 681984 sequences (100000153 bp) in 2.241 CPU sec, 2.332 real sec...
[M::mem_process_seqs] Processed 682724 reads in 155.281 CPU sec, 4.967 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 278579, 12, 24)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 296, 766)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1984)
[M::mem_pestat] mean and std.dev: (336.50, 255.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2593)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 336, 464)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 958)
[M::mem_pestat] mean and std.dev: (350.78, 166.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1205)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 663, 2160)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6098)
[M::mem_pestat] mean and std.dev: (936.83, 841.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8067)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 175, 287)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 551)
[M::mem_pestat] mean and std.dev: (192.29, 67.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 683)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 43, #reads = 1068591 mem = 536880268 peak = 1005694976
[M::process] read 681752 sequences (100000146 bp) in 3.434 CPU sec, 4.036 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 278122, 13, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 335, 472)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1034)
[M::mem_pestat] mean and std.dev: (311.59, 171.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1315)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 337, 467)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 965)
[M::mem_pestat] mean and std.dev: (352.82, 168.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1214)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (375, 392, 538)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (49, 864)
[M::mem_pestat] mean and std.dev: (469.33, 76.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1027)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 318, 425)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 863)
[M::mem_pestat] mean and std.dev: (291.44, 126.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1082)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682322 reads in 245.641 CPU sec, 7.922 real sec
[M::mem_process_seqs] Processed 681984 reads in 163.174 CPU sec, 5.203 real sec
[M::process] read 681220 sequences (100000188 bp) in 2.857 CPU sec, 2.952 real sec...
sorting block 44, #reads = 1069780 mem = 536884322 peak = 1005694976
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 277854, 11, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 275, 517)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1223)
[M::mem_pestat] mean and std.dev: (329.16, 259.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1576)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 341, 474)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 984)
[M::mem_pestat] mean and std.dev: (356.62, 170.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1239)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 481, 1630)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4568)
[M::mem_pestat] mean and std.dev: (736.91, 682.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6037)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (263, 389, 531)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1067)
[M::mem_pestat] mean and std.dev: (350.13, 171.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1335)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 681030 sequences (100000181 bp) in 3.707 CPU sec, 4.143 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 277645, 3, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (245, 324, 452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 866)
[M::mem_pestat] mean and std.dev: (314.13, 107.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1073)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 343, 476)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 984)
[M::mem_pestat] mean and std.dev: (358.60, 170.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1238)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 335, 498)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1108)
[M::mem_pestat] mean and std.dev: (323.81, 153.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1413)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681752 reads in 238.208 CPU sec, 7.706 real sec
[M::mem_process_seqs] Processed 681220 reads in 156.427 CPU sec, 5.022 real sec
[M::process] read 680982 sequences (100000084 bp) in 2.817 CPU sec, 3.251 real sec...
sorting block 45, #reads = 1069512 mem = 536880293 peak = 1005694976
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 277196, 15, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 252, 315)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 607)
[M::mem_pestat] mean and std.dev: (250.59, 106.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 753)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 343, 475)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 981)
[M::mem_pestat] mean and std.dev: (358.75, 170.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1234)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (440, 618, 1098)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2414)
[M::mem_pestat] mean and std.dev: (700.13, 512.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3072)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 280, 613)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1471)
[M::mem_pestat] mean and std.dev: (359.58, 283.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1900)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 680844 sequences (100000015 bp) in 3.498 CPU sec, 3.897 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 277426, 4, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (250, 354, 438)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 814)
[M::mem_pestat] mean and std.dev: (322.07, 138.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1002)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 344, 475)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 979)
[M::mem_pestat] mean and std.dev: (359.14, 170.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1231)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 290, 510)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1076)
[M::mem_pestat] mean and std.dev: (329.25, 169.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1359)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681030 reads in 242.930 CPU sec, 7.779 real sec
[M::process] read 680878 sequences (100000032 bp) in 2.618 CPU sec, 2.741 real sec...
sorting block 46, #reads = 1069191 mem = 536883736 peak = 1005694976
[M::mem_process_seqs] Processed 680982 reads in 159.732 CPU sec, 5.054 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 278224, 6, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 329, 510)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1224)
[M::mem_pestat] mean and std.dev: (347.84, 216.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1581)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 345, 476)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 980)
[M::mem_pestat] mean and std.dev: (359.84, 170.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1232)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 419, 749)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1863)
[M::mem_pestat] mean and std.dev: (509.06, 408.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2420)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 47, #reads = 1066910 mem = 536879335 peak = 1009852416
[M::process] read 680750 sequences (100000068 bp) in 3.624 CPU sec, 4.085 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 276919, 13, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 258, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 703)
[M::mem_pestat] mean and std.dev: (253.32, 117.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 883)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 345, 476)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 980)
[M::mem_pestat] mean and std.dev: (359.56, 170.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1232)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (496, 758, 1882)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4654)
[M::mem_pestat] mean and std.dev: (909.50, 729.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6040)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 265, 506)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1102)
[M::mem_pestat] mean and std.dev: (340.35, 200.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1400)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 680792 sequences (100000281 bp) in 2.369 CPU sec, 2.378 real sec...
[M::mem_process_seqs] Processed 680844 reads in 236.140 CPU sec, 7.583 real sec
[M::mem_process_seqs] Processed 680878 reads in 154.243 CPU sec, 4.926 real sec
sorting block 48, #reads = 1067778 mem = 536879079 peak = 1009852416
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 277627, 25, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (249, 317, 462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 888)
[M::mem_pestat] mean and std.dev: (299.73, 122.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1101)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 345, 476)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 978)
[M::mem_pestat] mean and std.dev: (359.90, 169.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1229)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (451, 903, 3215)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8743)
[M::mem_pestat] mean and std.dev: (1461.12, 1269.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11507)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 299, 590)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1364)
[M::mem_pestat] mean and std.dev: (330.94, 211.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1751)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 680556 sequences (100000196 bp) in 3.355 CPU sec, 3.865 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 276363, 3, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 285, 924)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2342)
[M::mem_pestat] mean and std.dev: (622.75, 663.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3277)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 342, 473)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 973)
[M::mem_pestat] mean and std.dev: (357.62, 169.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1223)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (288, 429, 956)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2292)
[M::mem_pestat] mean and std.dev: (476.91, 385.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2960)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680750 reads in 240.128 CPU sec, 7.708 real sec
[M::process] read 680842 sequences (100000117 bp) in 2.407 CPU sec, 2.429 real sec...
[M::mem_process_seqs] Processed 680792 reads in 156.248 CPU sec, 4.979 real sec
sorting block 49, #reads = 1069003 mem = 536880919 peak = 1009852416
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 277063, 12, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 295, 578)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1290)
[M::mem_pestat] mean and std.dev: (424.77, 336.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1771)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 343, 472)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 970)
[M::mem_pestat] mean and std.dev: (357.98, 168.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1219)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 1163, 2134)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6034)
[M::mem_pestat] mean and std.dev: (1087.92, 920.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7984)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (246, 303, 451)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 861)
[M::mem_pestat] mean and std.dev: (313.94, 112.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1066)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 680916 sequences (100000015 bp) in 3.460 CPU sec, 3.790 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 277543, 3, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 315, 431)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 851)
[M::mem_pestat] mean and std.dev: (329.22, 162.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1061)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 342, 473)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 975)
[M::mem_pestat] mean and std.dev: (357.30, 169.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1226)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 362, 543)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1263)
[M::mem_pestat] mean and std.dev: (353.56, 190.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1623)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680894 sequences (100000232 bp) in 2.452 CPU sec, 2.459 real sec...
[M::mem_process_seqs] Processed 680556 reads in 238.445 CPU sec, 7.614 real sec
[M::mem_process_seqs] Processed 680842 reads in 155.488 CPU sec, 4.939 real sec
sorting block 50, #reads = 1067505 mem = 536878933 peak = 1009852416
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 277271, 6, 22)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 403, 567)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1273)
[M::mem_pestat] mean and std.dev: (362.13, 203.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1626)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 339, 469)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 965)
[M::mem_pestat] mean and std.dev: (355.15, 168.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1213)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 283, 389)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 789)
[M::mem_pestat] mean and std.dev: (288.68, 142.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 989)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680710 sequences (100000286 bp) in 3.685 CPU sec, 4.117 real sec...
sorting block 51, #reads = 1068231 mem = 536876943 peak = 1009852416
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 277556, 5, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (227, 358, 604)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1358)
[M::mem_pestat] mean and std.dev: (369.04, 243.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1735)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 336, 464)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 950)
[M::mem_pestat] mean and std.dev: (352.67, 167.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1193)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 296, 398)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 758)
[M::mem_pestat] mean and std.dev: (289.88, 101.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 938)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680916 reads in 245.743 CPU sec, 7.912 real sec
[M::process] read 680592 sequences (100000146 bp) in 2.635 CPU sec, 2.726 real sec...
[M::mem_process_seqs] Processed 680894 reads in 160.609 CPU sec, 5.149 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 277128, 7, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 287, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 612)
[M::mem_pestat] mean and std.dev: (280.34, 127.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 789)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 336, 465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 955)
[M::mem_pestat] mean and std.dev: (352.83, 167.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1200)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 293, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 682)
[M::mem_pestat] mean and std.dev: (250.35, 131.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 857)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 52, #reads = 1067874 mem = 536877012 peak = 1009852416
[M::process] read 680852 sequences (100000033 bp) in 3.900 CPU sec, 4.241 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 277116, 10, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 227, 443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1031)
[M::mem_pestat] mean and std.dev: (307.64, 185.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1325)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 339, 468)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 958)
[M::mem_pestat] mean and std.dev: (355.54, 167.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1203)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (5, 270, 1865)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5585)
[M::mem_pestat] mean and std.dev: (746.00, 975.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7445)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (320, 358, 486)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 818)
[M::mem_pestat] mean and std.dev: (398.05, 193.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1174)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 680502 sequences (100000294 bp) in 2.098 CPU sec, 2.152 real sec...
[M::mem_process_seqs] Processed 680710 reads in 246.597 CPU sec, 7.889 real sec
[M::mem_process_seqs] Processed 680592 reads in 161.310 CPU sec, 5.127 real sec
sorting block 53, #reads = 1068257 mem = 536877544 peak = 1009852416
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 276996, 5, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 294, 420)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 832)
[M::mem_pestat] mean and std.dev: (272.29, 109.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1038)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 337, 463)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 947)
[M::mem_pestat] mean and std.dev: (352.13, 164.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1189)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 276, 412)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 836)
[M::mem_pestat] mean and std.dev: (322.73, 189.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1082)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680368 sequences (100000301 bp) in 3.857 CPU sec, 4.513 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 277148, 11, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 320, 515)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1101)
[M::mem_pestat] mean and std.dev: (334.97, 188.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1394)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 340, 466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 950)
[M::mem_pestat] mean and std.dev: (355.00, 166.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1192)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (426, 456, 3488)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9612)
[M::mem_pestat] mean and std.dev: (1623.18, 1581.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12674)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 352, 545)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1243)
[M::mem_pestat] mean and std.dev: (384.52, 232.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1592)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680852 reads in 248.034 CPU sec, 7.959 real sec
[M::process] read 679990 sequences (100000051 bp) in 2.676 CPU sec, 2.779 real sec...
[M::mem_process_seqs] Processed 680502 reads in 158.674 CPU sec, 5.046 real sec
sorting block 54, #reads = 1066811 mem = 536879984 peak = 1009852416
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 277432, 7, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 296, 685)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1695)
[M::mem_pestat] mean and std.dev: (339.07, 235.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2200)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 342, 468)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 954)
[M::mem_pestat] mean and std.dev: (356.28, 166.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1197)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (235, 428, 628)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1414)
[M::mem_pestat] mean and std.dev: (469.43, 311.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1807)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 679972 sequences (100000156 bp) in 3.854 CPU sec, 4.316 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 277269, 13, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (137, 224, 327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 707)
[M::mem_pestat] mean and std.dev: (209.07, 126.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 897)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 343, 470)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 958)
[M::mem_pestat] mean and std.dev: (358.36, 168.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1202)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (306, 360, 1176)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2916)
[M::mem_pestat] mean and std.dev: (515.17, 447.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3786)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 298, 628)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1494)
[M::mem_pestat] mean and std.dev: (356.49, 198.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1927)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680368 reads in 240.942 CPU sec, 7.729 real sec
[M::mem_process_seqs] Processed 679990 reads in 154.152 CPU sec, 4.884 real sec
sorting block 55, #reads = 1067543 mem = 536878575 peak = 1009852416
[M::process] read 679822 sequences (100000242 bp) in 3.129 CPU sec, 3.472 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 276761, 13, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 317, 576)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1308)
[M::mem_pestat] mean and std.dev: (435.72, 341.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1803)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 342, 470)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 958)
[M::mem_pestat] mean and std.dev: (358.37, 168.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1202)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (406, 511, 1398)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3382)
[M::mem_pestat] mean and std.dev: (888.69, 871.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4375)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (144, 280, 425)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 987)
[M::mem_pestat] mean and std.dev: (275.19, 165.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1268)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 679592 sequences (100000073 bp) in 3.570 CPU sec, 3.894 real sec...
sorting block 56, #reads = 1068385 mem = 536877392 peak = 1009852416
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 276922, 10, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (253, 354, 436)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 802)
[M::mem_pestat] mean and std.dev: (344.79, 132.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 985)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 341, 469)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 955)
[M::mem_pestat] mean and std.dev: (357.55, 167.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1198)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (58, 479, 823)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2353)
[M::mem_pestat] mean and std.dev: (343.38, 297.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3118)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 294, 470)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 956)
[M::mem_pestat] mean and std.dev: (328.71, 141.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1199)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 679972 reads in 238.000 CPU sec, 7.640 real sec
[M::mem_process_seqs] Processed 679822 reads in 157.171 CPU sec, 4.981 real sec
[M::process] read 681882 sequences (100000281 bp) in 2.808 CPU sec, 2.937 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (21, 276814, 5, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (258, 435, 880)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2124)
[M::mem_pestat] mean and std.dev: (502.17, 322.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2746)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 343, 469)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 953)
[M::mem_pestat] mean and std.dev: (358.57, 167.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1195)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 239, 577)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1359)
[M::mem_pestat] mean and std.dev: (361.55, 253.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1750)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 57, #reads = 1067202 mem = 536878006 peak = 1009852416
[M::process] read 684268 sequences (100000054 bp) in 3.022 CPU sec, 3.404 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 277436, 25, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (251, 370, 471)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 911)
[M::mem_pestat] mean and std.dev: (377.00, 187.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1131)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 335, 464)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 956)
[M::mem_pestat] mean and std.dev: (351.28, 167.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1202)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 523, 1102)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2972)
[M::mem_pestat] mean and std.dev: (459.73, 361.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3907)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 318, 480)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1064)
[M::mem_pestat] mean and std.dev: (311.97, 159.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1356)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 679592 reads in 236.754 CPU sec, 7.696 real sec
[M::mem_process_seqs] Processed 681882 reads in 154.495 CPU sec, 5.000 real sec
[M::process] read 683522 sequences (100000299 bp) in 2.566 CPU sec, 3.208 real sec...
sorting block 58, #reads = 1067914 mem = 536878546 peak = 1009852416
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 278572, 19, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 214, 286)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 552)
[M::mem_pestat] mean and std.dev: (224.02, 99.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 685)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 322, 454)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 948)
[M::mem_pestat] mean and std.dev: (341.92, 167.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1195)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (258, 347, 1013)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2523)
[M::mem_pestat] mean and std.dev: (558.53, 440.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3278)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (290, 372, 747)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1661)
[M::mem_pestat] mean and std.dev: (461.94, 331.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2118)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 683402 sequences (100000155 bp) in 3.203 CPU sec, 3.608 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 278789, 4, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 239, 447)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 973)
[M::mem_pestat] mean and std.dev: (299.70, 173.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1236)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 325, 458)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 956)
[M::mem_pestat] mean and std.dev: (345.48, 169.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1205)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 308, 806)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2016)
[M::mem_pestat] mean and std.dev: (285.41, 153.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2621)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 684268 reads in 230.839 CPU sec, 7.405 real sec
[M::process] read 682984 sequences (100000160 bp) in 2.334 CPU sec, 2.367 real sec...
[M::mem_process_seqs] Processed 683522 reads in 148.107 CPU sec, 4.694 real sec
sorting block 59, #reads = 1067820 mem = 536886356 peak = 1009852416
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 278018, 3, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 191, 281)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 513)
[M::mem_pestat] mean and std.dev: (207.75, 74.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 629)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 328, 461)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 961)
[M::mem_pestat] mean and std.dev: (346.93, 169.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1211)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 286, 371)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 729)
[M::mem_pestat] mean and std.dev: (280.89, 95.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 908)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682866 sequences (100000006 bp) in 3.118 CPU sec, 3.603 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 277578, 4, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (248, 286, 502)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1010)
[M::mem_pestat] mean and std.dev: (314.28, 181.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1264)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 330, 461)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 957)
[M::mem_pestat] mean and std.dev: (348.05, 169.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1205)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 257, 427)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 953)
[M::mem_pestat] mean and std.dev: (307.03, 201.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1216)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683402 reads in 226.336 CPU sec, 7.320 real sec
sorting block 60, #reads = 1072094 mem = 536878775 peak = 1009852416
[M::mem_process_seqs] Processed 682984 reads in 148.724 CPU sec, 4.779 real sec
[M::process] read 682382 sequences (100000200 bp) in 2.472 CPU sec, 2.718 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 277901, 12, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (296, 372, 495)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 893)
[M::mem_pestat] mean and std.dev: (364.29, 166.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1092)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 332, 463)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 961)
[M::mem_pestat] mean and std.dev: (349.08, 168.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1210)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (408, 433, 477)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (270, 615)
[M::mem_pestat] mean and std.dev: (408.70, 50.40)
[M::mem_pestat] low and high boundaries for proper pairs: (201, 684)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 328, 441)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 879)
[M::mem_pestat] mean and std.dev: (351.82, 184.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1098)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 61, #reads = 1071318 mem = 536878597 peak = 1093373952
[M::process] read 682242 sequences (100000053 bp) in 3.308 CPU sec, 3.908 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 278080, 17, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (138, 208, 413)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 963)
[M::mem_pestat] mean and std.dev: (228.55, 114.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1238)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 334, 466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 966)
[M::mem_pestat] mean and std.dev: (351.19, 169.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1216)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (58, 76, 2226)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6562)
[M::mem_pestat] mean and std.dev: (780.25, 935.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8730)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 379, 935)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2351)
[M::mem_pestat] mean and std.dev: (577.37, 539.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3059)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682866 reads in 224.414 CPU sec, 7.320 real sec
[M::mem_process_seqs] Processed 682382 reads in 148.970 CPU sec, 4.813 real sec
[M::process] read 681608 sequences (100000135 bp) in 2.588 CPU sec, 2.825 real sec...
sorting block 62, #reads = 1070515 mem = 536884096 peak = 1093373952
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 277552, 13, 18)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 310, 498)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1172)
[M::mem_pestat] mean and std.dev: (278.03, 154.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1509)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 335, 465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 961)
[M::mem_pestat] mean and std.dev: (351.52, 168.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1209)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (698, 1676, 1676)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3632)
[M::mem_pestat] mean and std.dev: (1334.92, 515.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4610)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 222, 920)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2456)
[M::mem_pestat] mean and std.dev: (494.56, 439.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3224)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 681624 sequences (100000153 bp) in 3.706 CPU sec, 4.571 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 278277, 14, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 266, 630)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1456)
[M::mem_pestat] mean and std.dev: (449.81, 398.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2043)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 339, 469)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 969)
[M::mem_pestat] mean and std.dev: (354.96, 169.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1219)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (503, 515, 1022)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2060)
[M::mem_pestat] mean and std.dev: (659.14, 326.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2579)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (252, 400, 803)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1905)
[M::mem_pestat] mean and std.dev: (470.54, 266.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2456)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682242 reads in 229.784 CPU sec, 7.466 real sec
[M::mem_process_seqs] Processed 681608 reads in 150.842 CPU sec, 4.868 real sec
[M::process] read 681572 sequences (100000121 bp) in 2.903 CPU sec, 3.109 real sec...
sorting block 63, #reads = 1069764 mem = 536877488 peak = 1093373952
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 277605, 15, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 304, 561)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1289)
[M::mem_pestat] mean and std.dev: (335.22, 199.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1653)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 340, 472)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 976)
[M::mem_pestat] mean and std.dev: (356.10, 170.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1228)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1878, 1878, 2092)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1450, 2520)
[M::mem_pestat] mean and std.dev: (1925.56, 88.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1236, 2734)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 300, 514)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1102)
[M::mem_pestat] mean and std.dev: (322.31, 161.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1396)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 681340 sequences (100000234 bp) in 3.282 CPU sec, 3.884 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 278028, 6, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 282, 421)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 957)
[M::mem_pestat] mean and std.dev: (286.18, 138.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1225)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 340, 472)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 976)
[M::mem_pestat] mean and std.dev: (356.57, 170.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1228)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (232, 311, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (8, 568)
[M::mem_pestat] mean and std.dev: (298.51, 107.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 730)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681624 reads in 227.171 CPU sec, 7.295 real sec
sorting block 64, #reads = 1069847 mem = 536879940 peak = 1093373952
[M::mem_process_seqs] Processed 681572 reads in 147.470 CPU sec, 4.691 real sec
[M::process] read 681024 sequences (100000234 bp) in 2.852 CPU sec, 3.034 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 277639, 13, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 275, 552)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1350)
[M::mem_pestat] mean and std.dev: (357.92, 255.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1749)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 343, 477)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 989)
[M::mem_pestat] mean and std.dev: (359.65, 172.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1245)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 191, 616)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1526)
[M::mem_pestat] mean and std.dev: (322.00, 288.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1981)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 333, 1565)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4293)
[M::mem_pestat] mean and std.dev: (706.97, 746.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5657)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 65, #reads = 1070926 mem = 536878430 peak = 1093373952
[M::process] read 680996 sequences (100000180 bp) in 3.328 CPU sec, 3.853 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 277692, 6, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (247, 409, 912)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2242)
[M::mem_pestat] mean and std.dev: (618.18, 475.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2907)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 344, 478)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 990)
[M::mem_pestat] mean and std.dev: (360.65, 172.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1246)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 277, 455)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 961)
[M::mem_pestat] mean and std.dev: (271.89, 130.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1214)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681340 reads in 233.164 CPU sec, 7.486 real sec
[M::process] read 681168 sequences (100000238 bp) in 2.400 CPU sec, 2.435 real sec...
[M::mem_process_seqs] Processed 681024 reads in 151.484 CPU sec, 4.807 real sec
sorting block 66, #reads = 1068800 mem = 536879606 peak = 1093373952
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 277915, 9, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (145, 236, 453)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1069)
[M::mem_pestat] mean and std.dev: (300.70, 191.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1377)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 344, 480)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 996)
[M::mem_pestat] mean and std.dev: (361.92, 174.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1254)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 269, 464)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 968)
[M::mem_pestat] mean and std.dev: (303.23, 117.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1220)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681054 sequences (100000011 bp) in 3.695 CPU sec, 4.056 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 278018, 14, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 312, 645)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1495)
[M::mem_pestat] mean and std.dev: (401.51, 294.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1920)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 344, 479)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 993)
[M::mem_pestat] mean and std.dev: (361.01, 173.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1250)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (574, 589, 779)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (164, 1189)
[M::mem_pestat] mean and std.dev: (645.42, 129.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1394)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 405, 561)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1289)
[M::mem_pestat] mean and std.dev: (393.23, 238.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1653)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680996 reads in 235.993 CPU sec, 7.555 real sec
[M::process] read 681130 sequences (100000205 bp) in 2.368 CPU sec, 2.370 real sec...
[M::mem_process_seqs] Processed 681168 reads in 152.947 CPU sec, 4.855 real sec
sorting block 67, #reads = 1069271 mem = 536879027 peak = 1093373952
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 277020, 20, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 187, 412)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 938)
[M::mem_pestat] mean and std.dev: (275.52, 182.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1201)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 342, 476)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 986)
[M::mem_pestat] mean and std.dev: (358.81, 171.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1241)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 470, 1936)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5486)
[M::mem_pestat] mean and std.dev: (1205.40, 1379.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7261)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 283, 426)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 850)
[M::mem_pestat] mean and std.dev: (285.03, 123.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1062)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 681284 sequences (100000033 bp) in 3.767 CPU sec, 4.168 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 277777, 12, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 280, 390)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 852)
[M::mem_pestat] mean and std.dev: (299.77, 164.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1083)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 341, 475)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 985)
[M::mem_pestat] mean and std.dev: (358.17, 172.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1240)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (52, 58, 2214)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6538)
[M::mem_pestat] mean and std.dev: (912.08, 1375.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8700)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 276, 409)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 865)
[M::mem_pestat] mean and std.dev: (286.61, 123.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1093)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681054 reads in 233.832 CPU sec, 7.478 real sec
[M::process] read 681518 sequences (100000264 bp) in 2.858 CPU sec, 2.932 real sec...
[M::mem_process_seqs] Processed 681130 reads in 154.716 CPU sec, 4.892 real sec
sorting block 68, #reads = 1069102 mem = 536877152 peak = 1093373952
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 277300, 19, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (138, 276, 642)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1650)
[M::mem_pestat] mean and std.dev: (338.08, 320.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2154)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 338, 472)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 980)
[M::mem_pestat] mean and std.dev: (356.24, 171.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1234)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (685, 699, 2097)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4921)
[M::mem_pestat] mean and std.dev: (1246.21, 1112.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6333)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 285, 555)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1211)
[M::mem_pestat] mean and std.dev: (340.40, 169.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1539)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 681856 sequences (100000216 bp) in 3.429 CPU sec, 3.859 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 277400, 8, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 213, 397)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 857)
[M::mem_pestat] mean and std.dev: (247.61, 136.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1087)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 337, 471)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 977)
[M::mem_pestat] mean and std.dev: (355.08, 170.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1230)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 288, 454)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 992)
[M::mem_pestat] mean and std.dev: (306.36, 139.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1261)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681284 reads in 227.686 CPU sec, 7.283 real sec
sorting block 69, #reads = 1069069 mem = 536877591 peak = 1093373952
[M::process] read 681644 sequences (100000207 bp) in 2.944 CPU sec, 3.004 real sec...
[M::mem_process_seqs] Processed 681518 reads in 156.137 CPU sec, 4.942 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 277756, 15, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (130, 237, 312)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 676)
[M::mem_pestat] mean and std.dev: (230.57, 111.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 858)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 335, 469)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 975)
[M::mem_pestat] mean and std.dev: (353.14, 170.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1228)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (37, 75, 248)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 670)
[M::mem_pestat] mean and std.dev: (121.50, 91.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 881)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 316, 642)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1522)
[M::mem_pestat] mean and std.dev: (386.97, 239.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1962)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 70, #reads = 1069711 mem = 536878241 peak = 1093373952
[M::process] read 681518 sequences (100000149 bp) in 3.674 CPU sec, 3.941 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 277535, 13, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 282, 388)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 812)
[M::mem_pestat] mean and std.dev: (271.27, 124.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1024)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 335, 467)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 967)
[M::mem_pestat] mean and std.dev: (352.65, 169.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1217)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (438, 871, 3546)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9762)
[M::mem_pestat] mean and std.dev: (1645.38, 1455.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12870)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 233, 353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 665)
[M::mem_pestat] mean and std.dev: (247.83, 99.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 821)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 681640 sequences (100000102 bp) in 2.597 CPU sec, 2.600 real sec...
[M::mem_process_seqs] Processed 681856 reads in 242.518 CPU sec, 7.734 real sec
[M::mem_process_seqs] Processed 681644 reads in 162.414 CPU sec, 5.152 real sec
sorting block 71, #reads = 1068870 mem = 536885465 peak = 1093373952
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 277557, 5, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (143, 237, 469)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1121)
[M::mem_pestat] mean and std.dev: (320.90, 249.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1447)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 333, 465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 961)
[M::mem_pestat] mean and std.dev: (351.48, 169.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1209)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 268, 433)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 899)
[M::mem_pestat] mean and std.dev: (332.71, 183.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1132)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681392 sequences (100000051 bp) in 3.989 CPU sec, 4.263 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 278271, 7, 22)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 298, 512)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1132)
[M::mem_pestat] mean and std.dev: (343.98, 195.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1442)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 335, 467)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 967)
[M::mem_pestat] mean and std.dev: (353.54, 170.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1217)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 206, 264)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 442)
[M::mem_pestat] mean and std.dev: (207.68, 55.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 531)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681388 sequences (100000251 bp) in 2.583 CPU sec, 2.589 real sec...
[M::mem_process_seqs] Processed 681518 reads in 244.950 CPU sec, 7.794 real sec
[M::mem_process_seqs] Processed 681640 reads in 160.549 CPU sec, 5.083 real sec
sorting block 72, #reads = 1069260 mem = 536878134 peak = 1093373952
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (19, 277665, 6, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 175, 307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 571)
[M::mem_pestat] mean and std.dev: (193.38, 71.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 703)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 332, 460)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 946)
[M::mem_pestat] mean and std.dev: (349.11, 166.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1189)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 250, 429)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 877)
[M::mem_pestat] mean and std.dev: (295.85, 141.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1101)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680970 sequences (100000121 bp) in 3.520 CPU sec, 3.806 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 277062, 4, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (236, 404, 471)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 941)
[M::mem_pestat] mean and std.dev: (330.83, 137.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1176)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 334, 462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 948)
[M::mem_pestat] mean and std.dev: (350.49, 166.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1191)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 267, 374)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 816)
[M::mem_pestat] mean and std.dev: (273.95, 155.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1037)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681392 reads in 241.883 CPU sec, 7.739 real sec
[M::process] read 680612 sequences (100000252 bp) in 2.520 CPU sec, 2.545 real sec...
sorting block 73, #reads = 1068698 mem = 536880584 peak = 1093373952
[M::mem_process_seqs] Processed 681388 reads in 158.133 CPU sec, 4.994 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 277099, 9, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 346, 588)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1380)
[M::mem_pestat] mean and std.dev: (376.10, 231.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1776)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 337, 466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 958)
[M::mem_pestat] mean and std.dev: (353.77, 168.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1204)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 296, 438)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1012)
[M::mem_pestat] mean and std.dev: (313.07, 164.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1299)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 74, #reads = 1068155 mem = 536878607 peak = 1093373952
[M::process] read 680648 sequences (100000280 bp) in 3.914 CPU sec, 4.270 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 277188, 7, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 235, 327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 667)
[M::mem_pestat] mean and std.dev: (245.67, 111.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 837)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 338, 466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 954)
[M::mem_pestat] mean and std.dev: (354.73, 167.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1198)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 270, 412)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 812)
[M::mem_pestat] mean and std.dev: (302.49, 147.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1012)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680970 reads in 237.963 CPU sec, 7.602 real sec
[M::mem_process_seqs] Processed 680612 reads in 154.671 CPU sec, 4.880 real sec
[M::process] read 680424 sequences (100000011 bp) in 2.961 CPU sec, 3.035 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 277466, 7, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 264, 492)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1130)
[M::mem_pestat] mean and std.dev: (279.66, 142.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1449)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 340, 469)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 963)
[M::mem_pestat] mean and std.dev: (356.26, 169.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1210)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 279, 433)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 917)
[M::mem_pestat] mean and std.dev: (318.03, 158.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1159)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 75, #reads = 1068926 mem = 536877805 peak = 1093373952
[M::process] read 680412 sequences (100000286 bp) in 3.624 CPU sec, 4.469 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 277823, 23, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 229, 270)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (39, 424)
[M::mem_pestat] mean and std.dev: (227.93, 83.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 560)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 340, 471)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 967)
[M::mem_pestat] mean and std.dev: (357.51, 169.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1215)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (142, 416, 2001)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5719)
[M::mem_pestat] mean and std.dev: (1094.74, 981.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7578)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 254, 477)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1093)
[M::mem_pestat] mean and std.dev: (349.12, 239.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1401)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680648 reads in 240.467 CPU sec, 7.681 real sec
[M::mem_process_seqs] Processed 680424 reads in 154.601 CPU sec, 4.876 real sec
[M::process] read 680322 sequences (100000132 bp) in 2.860 CPU sec, 2.947 real sec...
sorting block 76, #reads = 1067610 mem = 536879620 peak = 1093373952
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 277688, 9, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 300, 380)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 718)
[M::mem_pestat] mean and std.dev: (279.32, 112.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 887)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 340, 471)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 967)
[M::mem_pestat] mean and std.dev: (357.54, 170.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1215)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (248, 327, 587)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1265)
[M::mem_pestat] mean and std.dev: (365.07, 172.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1604)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 684094 sequences (100000096 bp) in 4.359 CPU sec, 4.737 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 277376, 11, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (225, 400, 439)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 867)
[M::mem_pestat] mean and std.dev: (326.52, 129.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1081)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 341, 471)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 965)
[M::mem_pestat] mean and std.dev: (358.25, 170.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1212)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (555, 692, 708)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (249, 1014)
[M::mem_pestat] mean and std.dev: (617.43, 148.44)
[M::mem_pestat] low and high boundaries for proper pairs: (24, 1211)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 300, 449)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 955)
[M::mem_pestat] mean and std.dev: (317.75, 145.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1208)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680412 reads in 243.386 CPU sec, 7.789 real sec
[M::mem_process_seqs] Processed 680322 reads in 153.848 CPU sec, 4.863 real sec
sorting block 77, #reads = 1067966 mem = 536878975 peak = 1093373952
[M::process] read 687016 sequences (100000265 bp) in 3.110 CPU sec, 3.276 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 278966, 6, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 211, 290)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 534)
[M::mem_pestat] mean and std.dev: (220.47, 91.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 656)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 321, 457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 957)
[M::mem_pestat] mean and std.dev: (343.82, 170.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1207)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 258, 505)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1121)
[M::mem_pestat] mean and std.dev: (301.46, 161.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1429)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 686936 sequences (100000026 bp) in 4.032 CPU sec, 4.355 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 280423, 5, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (124, 169, 609)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1579)
[M::mem_pestat] mean and std.dev: (301.26, 295.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2064)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 306, 446)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 948)
[M::mem_pestat] mean and std.dev: (332.70, 169.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1199)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 275, 490)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1118)
[M::mem_pestat] mean and std.dev: (355.70, 218.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1432)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 685530 sequences (100000002 bp) in 2.270 CPU sec, 2.273 real sec...
[M::mem_process_seqs] Processed 684094 reads in 263.848 CPU sec, 8.425 real sec
sorting block 78, #reads = 1067449 mem = 536882987 peak = 1093373952
[M::mem_process_seqs] Processed 687016 reads in 166.893 CPU sec, 5.292 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 280045, 5, 23)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 224, 466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1046)
[M::mem_pestat] mean and std.dev: (311.40, 191.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1336)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 306, 446)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 946)
[M::mem_pestat] mean and std.dev: (331.70, 168.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1196)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 277, 498)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1180)
[M::mem_pestat] mean and std.dev: (343.87, 191.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1521)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 79, #reads = 1066864 mem = 536879301 peak = 1093373952
[M::process] read 685350 sequences (100000108 bp) in 3.905 CPU sec, 4.296 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 279566, 9, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 338, 439)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 909)
[M::mem_pestat] mean and std.dev: (287.04, 117.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1144)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 315, 455)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 965)
[M::mem_pestat] mean and std.dev: (338.81, 170.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1220)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 232, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 703)
[M::mem_pestat] mean and std.dev: (218.03, 79.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 884)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 684944 sequences (100000089 bp) in 2.530 CPU sec, 2.564 real sec...
[M::mem_process_seqs] Processed 686936 reads in 265.102 CPU sec, 8.485 real sec
[M::mem_process_seqs] Processed 685530 reads in 163.489 CPU sec, 5.184 real sec
sorting block 80, #reads = 1067591 mem = 536877830 peak = 1093373952
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (19, 279355, 6, 14)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (142, 290, 470)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1126)
[M::mem_pestat] mean and std.dev: (316.67, 228.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1454)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 318, 457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 967)
[M::mem_pestat] mean and std.dev: (340.48, 169.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1222)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 224, 290)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 596)
[M::mem_pestat] mean and std.dev: (207.92, 76.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 749)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 685070 sequences (100000049 bp) in 3.357 CPU sec, 4.065 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 279113, 10, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 263, 387)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 727)
[M::mem_pestat] mean and std.dev: (272.19, 103.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 897)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 320, 459)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 969)
[M::mem_pestat] mean and std.dev: (342.48, 170.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1224)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (62, 116, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 974)
[M::mem_pestat] mean and std.dev: (170.33, 139.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1278)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (253, 467, 552)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1150)
[M::mem_pestat] mean and std.dev: (432.35, 235.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1449)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 685350 reads in 247.413 CPU sec, 7.998 real sec
[M::process] read 685904 sequences (100000273 bp) in 2.585 CPU sec, 2.618 real sec...
[M::mem_process_seqs] Processed 684944 reads in 161.615 CPU sec, 5.163 real sec
sorting block 81, #reads = 1069728 mem = 536876494 peak = 1093373952
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20, 279966, 9, 22)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 223, 441)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 985)
[M::mem_pestat] mean and std.dev: (274.39, 186.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1257)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 317, 458)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 970)
[M::mem_pestat] mean and std.dev: (340.47, 169.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1226)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 354, 444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 938)
[M::mem_pestat] mean and std.dev: (323.25, 172.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1185)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 683842 sequences (100000287 bp) in 3.233 CPU sec, 3.612 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 279804, 4, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (109, 172, 310)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 712)
[M::mem_pestat] mean and std.dev: (212.19, 126.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 913)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 310, 447)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 943)
[M::mem_pestat] mean and std.dev: (334.33, 167.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1191)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 410, 474)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1048)
[M::mem_pestat] mean and std.dev: (320.29, 163.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1335)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 683522 sequences (100000017 bp) in 2.545 CPU sec, 2.554 real sec...
[M::mem_process_seqs] Processed 685070 reads in 245.121 CPU sec, 7.882 real sec
sorting block 82, #reads = 1070335 mem = 536881152 peak = 1093373952
[M::mem_process_seqs] Processed 685904 reads in 161.814 CPU sec, 5.147 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 279334, 16, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 225, 282)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 536)
[M::mem_pestat] mean and std.dev: (214.28, 84.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 663)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 328, 467)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 985)
[M::mem_pestat] mean and std.dev: (347.73, 171.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1244)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (128, 378, 623)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1613)
[M::mem_pestat] mean and std.dev: (375.67, 199.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2108)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 279, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 767)
[M::mem_pestat] mean and std.dev: (275.85, 133.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 967)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 83, #reads = 1071083 mem = 536879486 peak = 1093373952
[M::process] read 683130 sequences (100000040 bp) in 3.624 CPU sec, 4.010 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 279247, 12, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 391, 2581)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7313)
[M::mem_pestat] mean and std.dev: (1517.96, 2228.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10431)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 331, 468)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 984)
[M::mem_pestat] mean and std.dev: (349.40, 171.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1242)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (628, 885, 1310)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2674)
[M::mem_pestat] mean and std.dev: (682.00, 356.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3356)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 284, 424)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 908)
[M::mem_pestat] mean and std.dev: (287.64, 130.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1150)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 683066 sequences (100000268 bp) in 2.610 CPU sec, 2.619 real sec...
[M::mem_process_seqs] Processed 683842 reads in 246.235 CPU sec, 7.857 real sec
[M::mem_process_seqs] Processed 683522 reads in 157.862 CPU sec, 5.015 real sec
sorting block 84, #reads = 1068205 mem = 536880155 peak = 1093373952
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23, 278217, 10, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (225, 291, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 636)
[M::mem_pestat] mean and std.dev: (277.57, 96.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 773)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 333, 471)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 989)
[M::mem_pestat] mean and std.dev: (350.80, 170.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1248)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (226, 878, 2967)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8449)
[M::mem_pestat] mean and std.dev: (1390.50, 1310.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11190)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 335, 501)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1137)
[M::mem_pestat] mean and std.dev: (319.91, 170.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1455)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 683052 sequences (100000197 bp) in 3.764 CPU sec, 4.370 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 278460, 5, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (132, 269, 424)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1008)
[M::mem_pestat] mean and std.dev: (330.28, 261.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1375)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 334, 472)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 992)
[M::mem_pestat] mean and std.dev: (352.10, 170.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1252)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 225, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 758)
[M::mem_pestat] mean and std.dev: (228.17, 114.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 965)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 684156 sequences (100000181 bp) in 2.487 CPU sec, 2.494 real sec...
[M::mem_process_seqs] Processed 683130 reads in 254.365 CPU sec, 8.148 real sec
[M::mem_process_seqs] Processed 683066 reads in 165.656 CPU sec, 5.262 real sec
sorting block 85, #reads = 1068390 mem = 536878955 peak = 1093373952
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 278589, 15, 14)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 368, 452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1006)
[M::mem_pestat] mean and std.dev: (308.66, 171.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1283)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 335, 472)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 990)
[M::mem_pestat] mean and std.dev: (352.39, 171.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1249)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (716, 872, 1704)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3680)
[M::mem_pestat] mean and std.dev: (1164.00, 1000.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5166)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 325, 467)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1081)
[M::mem_pestat] mean and std.dev: (309.75, 207.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1388)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 683758 sequences (100000273 bp) in 3.971 CPU sec, 4.383 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 278875, 6, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 289, 469)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1041)
[M::mem_pestat] mean and std.dev: (325.10, 155.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1327)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 324, 461)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 971)
[M::mem_pestat] mean and std.dev: (343.92, 168.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1226)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 221, 282)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (24, 454)
[M::mem_pestat] mean and std.dev: (213.00, 58.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 540)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682064 sequences (100000100 bp) in 2.550 CPU sec, 2.556 real sec...
[M::mem_process_seqs] Processed 683052 reads in 252.459 CPU sec, 8.053 real sec
sorting block 86, #reads = 1066719 mem = 536880147 peak = 1093373952
[M::mem_process_seqs] Processed 684156 reads in 164.278 CPU sec, 5.213 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 279260, 10, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (232, 349, 414)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 778)
[M::mem_pestat] mean and std.dev: (305.38, 124.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 960)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 324, 460)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 964)
[M::mem_pestat] mean and std.dev: (343.49, 167.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1216)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (256, 306, 521)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1051)
[M::mem_pestat] mean and std.dev: (278.50, 171.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1316)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 301, 373)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 703)
[M::mem_pestat] mean and std.dev: (288.65, 123.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 868)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 87, #reads = 1068458 mem = 536879907 peak = 1093373952
[M::process] read 682490 sequences (100000253 bp) in 3.441 CPU sec, 3.856 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 278189, 6, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 259, 2023)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5639)
[M::mem_pestat] mean and std.dev: (1101.65, 1525.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7447)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 340, 478)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1004)
[M::mem_pestat] mean and std.dev: (356.52, 171.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1267)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (265, 327, 656)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1438)
[M::mem_pestat] mean and std.dev: (357.91, 237.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1829)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681934 sequences (100000032 bp) in 2.485 CPU sec, 2.490 real sec...
[M::mem_process_seqs] Processed 683758 reads in 259.700 CPU sec, 8.340 real sec
[M::mem_process_seqs] Processed 682064 reads in 166.744 CPU sec, 5.349 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 278454, 4, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 253, 353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 743)
[M::mem_pestat] mean and std.dev: (254.81, 159.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 938)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 337, 472)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 986)
[M::mem_pestat] mean and std.dev: (353.34, 169.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1243)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (314, 336, 373)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (196, 491)
[M::mem_pestat] mean and std.dev: (340.08, 40.34)
[M::mem_pestat] low and high boundaries for proper pairs: (137, 550)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 88, #reads = 1065976 mem = 536882543 peak = 1093373952
[M::process] read 681242 sequences (100000027 bp) in 3.596 CPU sec, 4.111 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 278120, 9, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 317, 648)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1534)
[M::mem_pestat] mean and std.dev: (287.80, 169.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1977)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 342, 477)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 995)
[M::mem_pestat] mean and std.dev: (356.88, 170.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1254)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 299, 395)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 813)
[M::mem_pestat] mean and std.dev: (281.28, 115.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1022)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680790 sequences (100000024 bp) in 2.431 CPU sec, 2.536 real sec...
[M::mem_process_seqs] Processed 682490 reads in 256.608 CPU sec, 8.247 real sec
[M::mem_process_seqs] Processed 681934 reads in 165.289 CPU sec, 5.269 real sec
sorting block 89, #reads = 1067403 mem = 536886236 peak = 1093373952
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 278256, 15, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 253, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 707)
[M::mem_pestat] mean and std.dev: (242.48, 97.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 890)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 341, 471)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 973)
[M::mem_pestat] mean and std.dev: (354.83, 166.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1224)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (591, 591, 1103)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2127)
[M::mem_pestat] mean and std.dev: (645.31, 306.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2639)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 265, 433)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 919)
[M::mem_pestat] mean and std.dev: (274.27, 132.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1162)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 680890 sequences (100000008 bp) in 3.585 CPU sec, 4.149 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 278200, 8, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 380, 554)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1274)
[M::mem_pestat] mean and std.dev: (393.74, 226.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1634)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 344, 472)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 972)
[M::mem_pestat] mean and std.dev: (356.62, 166.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1222)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 265, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 623)
[M::mem_pestat] mean and std.dev: (259.91, 107.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 764)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680884 sequences (100000236 bp) in 2.472 CPU sec, 2.475 real sec...
[M::mem_process_seqs] Processed 681242 reads in 252.444 CPU sec, 8.091 real sec
[M::mem_process_seqs] Processed 680790 reads in 160.066 CPU sec, 5.095 real sec
sorting block 90, #reads = 1065844 mem = 536880110 peak = 1093373952
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 277806, 12, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 323, 510)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1152)
[M::mem_pestat] mean and std.dev: (348.23, 194.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1473)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 343, 475)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 979)
[M::mem_pestat] mean and std.dev: (357.34, 167.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1231)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (667, 1251, 4422)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 11932)
[M::mem_pestat] mean and std.dev: (2266.75, 1856.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 15687)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (237, 302, 435)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 831)
[M::mem_pestat] mean and std.dev: (345.52, 195.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1128)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 680336 sequences (100000222 bp) in 3.628 CPU sec, 4.050 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 278296, 5, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (135, 290, 402)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 936)
[M::mem_pestat] mean and std.dev: (253.16, 121.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1203)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 341, 470)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 966)
[M::mem_pestat] mean and std.dev: (355.13, 165.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1214)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 263, 429)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 929)
[M::mem_pestat] mean and std.dev: (316.06, 202.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1179)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680546 sequences (100000216 bp) in 2.571 CPU sec, 2.607 real sec...
[M::mem_process_seqs] Processed 680890 reads in 262.783 CPU sec, 8.446 real sec
sorting block 91, #reads = 1065043 mem = 536879630 peak = 1093373952
[M::mem_process_seqs] Processed 680884 reads in 172.092 CPU sec, 5.463 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 276871, 12, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 272, 394)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 762)
[M::mem_pestat] mean and std.dev: (301.43, 147.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 946)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 346, 476)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 978)
[M::mem_pestat] mean and std.dev: (359.90, 168.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1229)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (441, 904, 1439)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3435)
[M::mem_pestat] mean and std.dev: (869.58, 517.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4433)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 214, 352)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 734)
[M::mem_pestat] mean and std.dev: (252.27, 102.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 925)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 92, #reads = 1062934 mem = 536878927 peak = 1093373952
[M::process] read 680412 sequences (100000038 bp) in 3.373 CPU sec, 3.686 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 277186, 8, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (125, 167, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 716)
[M::mem_pestat] mean and std.dev: (226.25, 143.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 913)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 343, 474)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 974)
[M::mem_pestat] mean and std.dev: (357.85, 167.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1224)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 220, 457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 999)
[M::mem_pestat] mean and std.dev: (254.98, 120.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1270)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680254 sequences (100000294 bp) in 2.685 CPU sec, 2.689 real sec...
[M::mem_process_seqs] Processed 680336 reads in 266.069 CPU sec, 8.532 real sec
[M::mem_process_seqs] Processed 680546 reads in 176.198 CPU sec, 5.599 real sec
sorting block 93, #reads = 1063672 mem = 536881083 peak = 1093373952
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (17, 277149, 6, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 207, 412)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 936)
[M::mem_pestat] mean and std.dev: (222.20, 106.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1198)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 344, 474)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 974)
[M::mem_pestat] mean and std.dev: (358.41, 167.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1224)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (238, 509, 808)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1948)
[M::mem_pestat] mean and std.dev: (552.45, 420.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2518)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680178 sequences (100000251 bp) in 3.500 CPU sec, 4.031 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 277195, 11, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 316, 472)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1072)
[M::mem_pestat] mean and std.dev: (327.78, 162.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1372)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 346, 476)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 978)
[M::mem_pestat] mean and std.dev: (360.40, 168.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1229)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (236, 384, 871)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2141)
[M::mem_pestat] mean and std.dev: (366.67, 193.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2776)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 320, 521)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1193)
[M::mem_pestat] mean and std.dev: (335.87, 173.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1529)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 680156 sequences (100000185 bp) in 2.477 CPU sec, 2.495 real sec...
[M::mem_process_seqs] Processed 680412 reads in 260.822 CPU sec, 8.360 real sec
[M::mem_process_seqs] Processed 680254 reads in 172.199 CPU sec, 5.497 real sec
sorting block 94, #reads = 1062973 mem = 536882453 peak = 1093373952
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 277425, 16, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 283, 405)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 829)
[M::mem_pestat] mean and std.dev: (288.23, 134.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1041)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 347, 479)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 987)
[M::mem_pestat] mean and std.dev: (361.83, 171.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1241)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (930, 1365, 4371)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 11253)
[M::mem_pestat] mean and std.dev: (2415.69, 1746.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14694)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 332, 418)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 850)
[M::mem_pestat] mean and std.dev: (284.78, 133.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1066)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 687684 sequences (100000213 bp) in 4.151 CPU sec, 4.510 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (17, 277522, 15, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 206, 443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1035)
[M::mem_pestat] mean and std.dev: (251.29, 147.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1331)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 350, 483)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 995)
[M::mem_pestat] mean and std.dev: (364.83, 172.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1251)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (553, 1275, 5449)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 15241)
[M::mem_pestat] mean and std.dev: (2029.33, 2100.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 20137)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 314, 432)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 954)
[M::mem_pestat] mean and std.dev: (300.48, 164.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1215)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 689558 sequences (100000177 bp) in 2.487 CPU sec, 2.497 real sec...
[M::mem_process_seqs] Processed 680178 reads in 264.503 CPU sec, 8.507 real sec
[M::mem_process_seqs] Processed 680156 reads in 174.380 CPU sec, 5.636 real sec
sorting block 95, #reads = 1062807 mem = 536881842 peak = 1093373952
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 279676, 9, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 317, 445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 971)
[M::mem_pestat] mean and std.dev: (322.03, 160.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1234)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 302, 436)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 922)
[M::mem_pestat] mean and std.dev: (325.17, 162.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1165)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 310, 597)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1351)
[M::mem_pestat] mean and std.dev: (362.90, 209.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1728)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 690100 sequences (100000164 bp) in 3.701 CPU sec, 4.202 real sec...
sorting block 96, #reads = 1061925 mem = 536881786 peak = 1093373952
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 281175, 10, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 230, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 681)
[M::mem_pestat] mean and std.dev: (251.88, 118.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 857)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 290, 421)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 887)
[M::mem_pestat] mean and std.dev: (313.92, 155.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1120)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (414, 2723, 8747)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 25413)
[M::mem_pestat] mean and std.dev: (3419.60, 3588.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 33746)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 367, 515)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1125)
[M::mem_pestat] mean and std.dev: (355.21, 186.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1430)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 687730 sequences (100000031 bp) in 2.670 CPU sec, 2.927 real sec...
[M::mem_process_seqs] Processed 687684 reads in 280.216 CPU sec, 9.020 real sec
[M::mem_process_seqs] Processed 689558 reads in 179.992 CPU sec, 5.772 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 281551, 24, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 403, 580)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1336)
[M::mem_pestat] mean and std.dev: (368.13, 196.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1714)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 288, 415)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 873)
[M::mem_pestat] mean and std.dev: (309.61, 151.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1102)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (387, 662, 1121)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2589)
[M::mem_pestat] mean and std.dev: (668.43, 313.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3323)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (250, 359, 528)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1084)
[M::mem_pestat] mean and std.dev: (351.73, 162.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1362)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 97, #reads = 1062899 mem = 536879909 peak = 1093373952
[M::process] read 686984 sequences (100000136 bp) in 3.297 CPU sec, 3.957 real sec...
[M::process] read 686210 sequences (100000028 bp) in 2.591 CPU sec, 2.597 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 280720, 5, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 248, 294)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 518)
[M::mem_pestat] mean and std.dev: (221.38, 89.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 630)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 299, 429)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 901)
[M::mem_pestat] mean and std.dev: (319.66, 155.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1137)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 222, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 707)
[M::mem_pestat] mean and std.dev: (240.58, 103.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 879)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 690100 reads in 283.757 CPU sec, 9.135 real sec
[M::mem_process_seqs] Processed 687730 reads in 179.969 CPU sec, 5.743 real sec
sorting block 98, #reads = 1063068 mem = 536881047 peak = 1093373952
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 280647, 6, 24)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 319, 409)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 839)
[M::mem_pestat] mean and std.dev: (288.57, 115.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1054)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 305, 435)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 913)
[M::mem_pestat] mean and std.dev: (324.34, 157.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1152)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (241, 460, 766)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1816)
[M::mem_pestat] mean and std.dev: (504.27, 349.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2341)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 685202 sequences (100000014 bp) in 3.408 CPU sec, 4.037 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 280218, 5, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 283, 393)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 807)
[M::mem_pestat] mean and std.dev: (267.87, 105.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1014)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 310, 442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 928)
[M::mem_pestat] mean and std.dev: (329.72, 160.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1171)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 289, 390)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 780)
[M::mem_pestat] mean and std.dev: (294.17, 127.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 975)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 684490 sequences (100000189 bp) in 2.591 CPU sec, 2.610 real sec...
[M::mem_process_seqs] Processed 686984 reads in 268.963 CPU sec, 8.643 real sec
[M::mem_process_seqs] Processed 686210 reads in 174.808 CPU sec, 5.552 real sec
sorting block 99, #reads = 1063966 mem = 536884040 peak = 1093373952
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 279667, 11, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 253, 463)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1017)
[M::mem_pestat] mean and std.dev: (328.11, 186.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1294)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 317, 450)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 944)
[M::mem_pestat] mean and std.dev: (335.79, 162.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1191)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (371, 441, 441)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (231, 581)
[M::mem_pestat] mean and std.dev: (410.57, 51.92)
[M::mem_pestat] low and high boundaries for proper pairs: (161, 651)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 302, 1884)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5210)
[M::mem_pestat] mean and std.dev: (916.00, 1021.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6873)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 684168 sequences (100000188 bp) in 3.831 CPU sec, 4.219 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 279525, 7, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (112, 205, 426)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1054)
[M::mem_pestat] mean and std.dev: (262.71, 169.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1368)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 322, 454)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 950)
[M::mem_pestat] mean and std.dev: (339.36, 163.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1198)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 249, 425)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 861)
[M::mem_pestat] mean and std.dev: (298.71, 153.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1079)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 684040 sequences (100000207 bp) in 2.650 CPU sec, 2.653 real sec...
[M::mem_process_seqs] Processed 685202 reads in 261.000 CPU sec, 8.337 real sec
sorting block 100, #reads = 1063885 mem = 536877787 peak = 1093373952
[M::mem_process_seqs] Processed 684490 reads in 166.021 CPU sec, 5.271 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 279708, 9, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (229, 276, 312)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (63, 478)
[M::mem_pestat] mean and std.dev: (278.78, 100.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 679)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 325, 459)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 963)
[M::mem_pestat] mean and std.dev: (342.22, 165.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1215)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 248, 530)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1224)
[M::mem_pestat] mean and std.dev: (335.80, 230.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1571)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 101, #reads = 1063857 mem = 536879018 peak = 1093373952
[M::process] read 683964 sequences (100000119 bp) in 3.889 CPU sec, 4.194 real sec...
[M::process] read 683630 sequences (100000017 bp) in 2.479 CPU sec, 2.486 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 279675, 4, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 374, 456)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 946)
[M::mem_pestat] mean and std.dev: (305.83, 128.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1191)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 325, 457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 957)
[M::mem_pestat] mean and std.dev: (341.17, 163.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1207)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 344, 516)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1200)
[M::mem_pestat] mean and std.dev: (350.24, 240.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1542)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 684168 reads in 260.529 CPU sec, 8.319 real sec
[M::mem_process_seqs] Processed 684040 reads in 174.096 CPU sec, 5.537 real sec
sorting block 102, #reads = 1064908 mem = 536881351 peak = 1093373952
[M::process] read 683558 sequences (100000275 bp) in 4.085 CPU sec, 4.308 real sec...
[M::process] read 683156 sequences (100000114 bp) in 2.596 CPU sec, 2.604 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 279290, 6, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 212, 233)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (14, 379)
[M::mem_pestat] mean and std.dev: (194.67, 55.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 452)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 327, 458)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 954)
[M::mem_pestat] mean and std.dev: (342.80, 162.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1202)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 315, 766)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1854)
[M::mem_pestat] mean and std.dev: (341.52, 205.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2398)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683630 reads in 151.077 CPU sec, 4.787 real sec
sorting block 103, #reads = 1062166 mem = 536879286 peak = 1093373952
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 279731, 12, 23)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (126, 231, 323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 717)
[M::mem_pestat] mean and std.dev: (212.39, 97.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 914)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 327, 460)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 964)
[M::mem_pestat] mean and std.dev: (343.06, 164.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1216)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (439, 1200, 1200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2722)
[M::mem_pestat] mean and std.dev: (865.55, 562.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3483)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 251, 348)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 674)
[M::mem_pestat] mean and std.dev: (231.40, 102.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 837)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 279723, 17, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (127, 215, 498)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1240)
[M::mem_pestat] mean and std.dev: (303.03, 203.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1611)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 327, 459)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 959)
[M::mem_pestat] mean and std.dev: (343.37, 163.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1209)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (806, 806, 811)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (796, 821)
[M::mem_pestat] mean and std.dev: (808.50, 2.50)
[M::mem_pestat] low and high boundaries for proper pairs: (791, 826)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 305, 507)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1137)
[M::mem_pestat] mean and std.dev: (358.46, 253.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1452)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682600 sequences (100000130 bp) in 2.759 CPU sec, 2.767 real sec...
[M::mem_process_seqs] Processed 683964 reads in 408.268 CPU sec, 12.989 real sec
[M::mem_process_seqs] Processed 683558 reads in 194.342 CPU sec, 6.212 real sec
sorting block 104, #reads = 1065258 mem = 536878979 peak = 1093373952
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 278531, 7, 23)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 298, 407)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 875)
[M::mem_pestat] mean and std.dev: (284.56, 122.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1109)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 330, 463)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 967)
[M::mem_pestat] mean and std.dev: (345.64, 164.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1219)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (256, 354, 448)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 832)
[M::mem_pestat] mean and std.dev: (343.77, 159.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1024)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682678 sequences (100000060 bp) in 4.132 CPU sec, 4.403 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 278726, 11, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 282, 494)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1106)
[M::mem_pestat] mean and std.dev: (303.58, 170.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1412)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 335, 467)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 973)
[M::mem_pestat] mean and std.dev: (349.89, 166.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1226)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (427, 559, 1007)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2167)
[M::mem_pestat] mean and std.dev: (658.80, 275.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2747)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 280, 476)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 974)
[M::mem_pestat] mean and std.dev: (322.03, 156.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1223)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682630 sequences (100000009 bp) in 2.554 CPU sec, 2.555 real sec...
[M::mem_process_seqs] Processed 683156 reads in 264.175 CPU sec, 8.410 real sec
sorting block 105, #reads = 1064105 mem = 536880357 peak = 1093373952
[M::process] read 681802 sequences (100000110 bp) in 2.847 CPU sec, 2.869 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 278651, 8, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 255, 462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1020)
[M::mem_pestat] mean and std.dev: (263.43, 166.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1299)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 332, 466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 972)
[M::mem_pestat] mean and std.dev: (348.94, 166.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1225)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (240, 348, 680)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1560)
[M::mem_pestat] mean and std.dev: (421.79, 262.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2000)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682678 reads in 153.584 CPU sec, 4.902 real sec
[M::mem_process_seqs] Processed 682600 reads in 369.223 CPU sec, 11.773 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 278561, 9, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (260, 461, 638)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1394)
[M::mem_pestat] mean and std.dev: (395.81, 176.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1772)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 334, 466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 972)
[M::mem_pestat] mean and std.dev: (348.98, 166.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1225)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 269, 585)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1417)
[M::mem_pestat] mean and std.dev: (419.49, 290.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1833)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 106, #reads = 1064483 mem = 536880274 peak = 1093373952
[M::process] read 681304 sequences (100000078 bp) in 3.807 CPU sec, 4.100 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 278179, 6, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 278, 446)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 980)
[M::mem_pestat] mean and std.dev: (312.81, 159.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1247)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 341, 474)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 986)
[M::mem_pestat] mean and std.dev: (355.04, 168.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1242)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 336, 491)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1023)
[M::mem_pestat] mean and std.dev: (365.38, 175.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1289)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682630 reads in 283.509 CPU sec, 9.025 real sec
[M::process] read 680682 sequences (100000012 bp) in 2.601 CPU sec, 2.637 real sec...
[M::mem_process_seqs] Processed 681802 reads in 170.151 CPU sec, 5.383 real sec
sorting block 107, #reads = 1062493 mem = 536879322 peak = 1093373952
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 276635, 4, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 227, 635)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1513)
[M::mem_pestat] mean and std.dev: (340.57, 249.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1952)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 344, 478)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 994)
[M::mem_pestat] mean and std.dev: (358.57, 169.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1252)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (230, 389, 478)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 974)
[M::mem_pestat] mean and std.dev: (328.09, 126.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1222)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680970 sequences (100000129 bp) in 4.558 CPU sec, 4.911 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 277194, 15, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 212, 417)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 927)
[M::mem_pestat] mean and std.dev: (260.94, 150.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1182)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 346, 479)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 991)
[M::mem_pestat] mean and std.dev: (360.17, 169.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1247)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1178, 1178, 1566)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (402, 2342)
[M::mem_pestat] mean and std.dev: (1447.20, 343.09)
[M::mem_pestat] low and high boundaries for proper pairs: (14, 2820)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 268, 388)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 870)
[M::mem_pestat] mean and std.dev: (274.05, 148.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1111)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681304 reads in 255.619 CPU sec, 8.140 real sec
[M::mem_process_seqs] Processed 680682 reads in 171.399 CPU sec, 5.406 real sec
[M::process] read 681060 sequences (100000138 bp) in 3.342 CPU sec, 3.425 real sec...
sorting block 108, #reads = 1065305 mem = 536878552 peak = 1093373952
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 277494, 13, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 334, 371)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 675)
[M::mem_pestat] mean and std.dev: (290.30, 104.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 827)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 345, 479)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 993)
[M::mem_pestat] mean and std.dev: (360.25, 170.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1250)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (326, 454, 515)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 893)
[M::mem_pestat] mean and std.dev: (331.58, 183.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1082)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 303, 484)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1070)
[M::mem_pestat] mean and std.dev: (285.88, 132.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1363)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 681056 sequences (100000009 bp) in 3.905 CPU sec, 4.159 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 277966, 7, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 295, 421)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 881)
[M::mem_pestat] mean and std.dev: (288.03, 130.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1111)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 346, 484)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1010)
[M::mem_pestat] mean and std.dev: (362.54, 174.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1273)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 337, 406)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 882)
[M::mem_pestat] mean and std.dev: (256.25, 105.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1120)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680768 sequences (100000083 bp) in 2.454 CPU sec, 2.464 real sec...
[M::mem_process_seqs] Processed 680970 reads in 259.794 CPU sec, 8.281 real sec
sorting block 109, #reads = 1063911 mem = 536879783 peak = 1093373952
[M::mem_process_seqs] Processed 681060 reads in 169.736 CPU sec, 5.386 real sec
sorting block 110, #reads = 1064455 mem = 536878290 peak = 1104535552
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 277728, 22, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 346, 379)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 811)
[M::mem_pestat] mean and std.dev: (315.20, 172.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1027)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 344, 483)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1009)
[M::mem_pestat] mean and std.dev: (361.53, 174.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1272)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (83, 389, 841)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2357)
[M::mem_pestat] mean and std.dev: (436.95, 344.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3115)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 378, 595)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1443)
[M::mem_pestat] mean and std.dev: (426.37, 304.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1867)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 681800 sequences (100000227 bp) in 3.926 CPU sec, 4.209 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 277586, 17, 22)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 397, 1461)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3967)
[M::mem_pestat] mean and std.dev: (896.84, 992.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5220)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 345, 482)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1002)
[M::mem_pestat] mean and std.dev: (362.00, 173.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1262)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 388, 888)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2316)
[M::mem_pestat] mean and std.dev: (638.35, 752.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3648)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 260, 577)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1333)
[M::mem_pestat] mean and std.dev: (298.30, 155.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1711)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 681402 sequences (100000182 bp) in 2.645 CPU sec, 2.655 real sec...
[M::mem_process_seqs] Processed 681056 reads in 261.257 CPU sec, 8.314 real sec
[M::mem_process_seqs] Processed 680768 reads in 170.015 CPU sec, 5.391 real sec
sorting block 111, #reads = 1064390 mem = 536877356 peak = 1104535552
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 278199, 11, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (276, 370, 443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 777)
[M::mem_pestat] mean and std.dev: (339.90, 111.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 944)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 337, 477)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 999)
[M::mem_pestat] mean and std.dev: (357.45, 175.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1260)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (389, 1410, 1853)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4781)
[M::mem_pestat] mean and std.dev: (1052.64, 745.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6245)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 279, 478)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1042)
[M::mem_pestat] mean and std.dev: (291.95, 124.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1324)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 686278 sequences (100000244 bp) in 4.055 CPU sec, 4.308 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (17, 277694, 13, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 202, 282)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 520)
[M::mem_pestat] mean and std.dev: (198.73, 56.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 639)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 342, 483)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1011)
[M::mem_pestat] mean and std.dev: (361.50, 176.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1275)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 201, 1848)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5196)
[M::mem_pestat] mean and std.dev: (877.85, 1255.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6870)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 267, 597)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1413)
[M::mem_pestat] mean and std.dev: (341.14, 208.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1821)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 687306 sequences (100000033 bp) in 2.889 CPU sec, 2.895 real sec...
[M::mem_process_seqs] Processed 681800 reads in 273.932 CPU sec, 8.734 real sec
[M::mem_process_seqs] Processed 681402 reads in 178.057 CPU sec, 5.643 real sec
sorting block 112, #reads = 1063265 mem = 536886602 peak = 1104535552
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 279355, 6, 23)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (135, 203, 532)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1326)
[M::mem_pestat] mean and std.dev: (293.26, 232.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1723)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 310, 445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 937)
[M::mem_pestat] mean and std.dev: (332.58, 165.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1183)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 265, 483)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1025)
[M::mem_pestat] mean and std.dev: (283.89, 143.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1296)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 686636 sequences (100000045 bp) in 3.864 CPU sec, 4.132 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 280272, 10, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 242, 487)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1121)
[M::mem_pestat] mean and std.dev: (293.80, 177.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1438)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 303, 437)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 923)
[M::mem_pestat] mean and std.dev: (325.79, 161.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1166)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (347, 423, 1331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3299)
[M::mem_pestat] mean and std.dev: (799.20, 676.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4283)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 287, 681)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1723)
[M::mem_pestat] mean and std.dev: (394.06, 346.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2244)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 685482 sequences (100000062 bp) in 2.958 CPU sec, 2.965 real sec...
[M::mem_process_seqs] Processed 686278 reads in 279.775 CPU sec, 8.915 real sec
sorting block 113, #reads = 1056730 mem = 536879017 peak = 1104535552
[M::mem_process_seqs] Processed 687306 reads in 174.172 CPU sec, 5.522 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 279823, 10, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 224, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 632)
[M::mem_pestat] mean and std.dev: (223.55, 69.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 779)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 307, 441)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 929)
[M::mem_pestat] mean and std.dev: (328.76, 162.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1173)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (313, 1701, 6187)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 17935)
[M::mem_pestat] mean and std.dev: (2364.00, 2562.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 23809)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 267, 544)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1298)
[M::mem_pestat] mean and std.dev: (360.52, 301.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1675)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 114, #reads = 1062978 mem = 536878872 peak = 1104535552
[M::process] read 684872 sequences (100000157 bp) in 4.837 CPU sec, 5.142 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 279701, 4, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (239, 318, 514)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1064)
[M::mem_pestat] mean and std.dev: (329.45, 151.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1339)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 315, 447)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 937)
[M::mem_pestat] mean and std.dev: (334.89, 164.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1182)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 389, 525)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1175)
[M::mem_pestat] mean and std.dev: (373.72, 168.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1500)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 686636 reads in 263.690 CPU sec, 8.431 real sec
[M::mem_process_seqs] Processed 685482 reads in 171.293 CPU sec, 5.407 real sec
[M::process] read 684244 sequences (100000182 bp) in 3.284 CPU sec, 3.398 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 279305, 5, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 309, 391)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 753)
[M::mem_pestat] mean and std.dev: (290.42, 105.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 934)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 319, 451)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 945)
[M::mem_pestat] mean and std.dev: (337.97, 165.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1192)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 343, 474)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 986)
[M::mem_pestat] mean and std.dev: (326.27, 139.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1242)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 115, #reads = 1067805 mem = 536888416 peak = 1104535552
[M::process] read 684290 sequences (100000022 bp) in 4.970 CPU sec, 5.437 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 279078, 10, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 243, 413)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 823)
[M::mem_pestat] mean and std.dev: (289.57, 164.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1028)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 322, 455)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 953)
[M::mem_pestat] mean and std.dev: (341.08, 165.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1202)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 591, 591)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1353)
[M::mem_pestat] mean and std.dev: (403.70, 197.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1734)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 508, 1005)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2557)
[M::mem_pestat] mean and std.dev: (635.74, 467.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3333)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 684872 reads in 261.595 CPU sec, 8.388 real sec
[M::mem_process_seqs] Processed 684244 reads in 160.363 CPU sec, 5.096 real sec
[M::process] read 683584 sequences (100000286 bp) in 3.661 CPU sec, 3.934 real sec...
sorting block 116, #reads = 1068936 mem = 536880259 peak = 1104535552
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (22, 279190, 12, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (298, 562, 1237)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3115)
[M::mem_pestat] mean and std.dev: (681.05, 407.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4054)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 322, 456)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 956)
[M::mem_pestat] mean and std.dev: (341.31, 166.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1206)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (23, 84, 5984)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 17906)
[M::mem_pestat] mean and std.dev: (1592.17, 2544.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 23867)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 280, 394)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 732)
[M::mem_pestat] mean and std.dev: (272.30, 92.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 901)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 683340 sequences (100000211 bp) in 4.233 CPU sec, 4.612 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 278964, 11, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 276, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 707)
[M::mem_pestat] mean and std.dev: (261.07, 96.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 879)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 328, 462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 968)
[M::mem_pestat] mean and std.dev: (345.55, 167.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1221)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (145, 608, 703)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1819)
[M::mem_pestat] mean and std.dev: (381.70, 286.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2377)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 305, 437)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 823)
[M::mem_pestat] mean and std.dev: (304.51, 127.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1016)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 684290 reads in 244.348 CPU sec, 7.837 real sec
sorting block 117, #reads = 1069328 mem = 536883865 peak = 1104535552
[M::process] read 683010 sequences (100000204 bp) in 4.007 CPU sec, 4.314 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 279008, 8, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (392, 521, 1267)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3017)
[M::mem_pestat] mean and std.dev: (570.42, 358.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3892)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 331, 465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 973)
[M::mem_pestat] mean and std.dev: (348.26, 168.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1227)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 255, 347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 713)
[M::mem_pestat] mean and std.dev: (256.06, 102.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 896)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683340 reads in 140.110 CPU sec, 4.426 real sec
[M::process] read 682916 sequences (100000018 bp) in 3.520 CPU sec, 3.725 real sec...
sorting block 118, #reads = 1070010 mem = 536879451 peak = 1104535552
[M::mem_process_seqs] Processed 683584 reads in 387.546 CPU sec, 12.281 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 279426, 7, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (130, 318, 593)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1519)
[M::mem_pestat] mean and std.dev: (343.53, 209.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1982)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 333, 465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 969)
[M::mem_pestat] mean and std.dev: (348.80, 167.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1221)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 240, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 548)
[M::mem_pestat] mean and std.dev: (253.61, 74.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 660)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 278685, 12, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 283, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 700)
[M::mem_pestat] mean and std.dev: (285.49, 143.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 869)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 333, 466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 972)
[M::mem_pestat] mean and std.dev: (349.49, 167.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1225)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (122, 300, 2299)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6653)
[M::mem_pestat] mean and std.dev: (793.83, 951.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8830)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 246, 442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 946)
[M::mem_pestat] mean and std.dev: (284.09, 130.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1198)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682784 sequences (100000050 bp) in 4.208 CPU sec, 4.520 real sec...
[M::mem_process_seqs] Processed 683010 reads in 274.511 CPU sec, 8.721 real sec
[M::mem_process_seqs] Processed 682916 reads in 159.511 CPU sec, 5.068 real sec
sorting block 119, #reads = 1067977 mem = 536879018 peak = 1104535552
[M::process] read 682946 sequences (100000116 bp) in 3.578 CPU sec, 3.821 real sec...
[M::process] read 682386 sequences (100000267 bp) in 3.278 CPU sec, 3.566 real sec...
[M::process] read 682316 sequences (100000198 bp) in 2.317 CPU sec, 2.326 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 278736, 8, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 347, 604)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1374)
[M::mem_pestat] mean and std.dev: (338.35, 175.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1759)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 337, 471)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 981)
[M::mem_pestat] mean and std.dev: (353.00, 168.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1236)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (328, 328, 549)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 991)
[M::mem_pestat] mean and std.dev: (381.94, 150.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1212)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682386 reads in 128.399 CPU sec, 4.258 real sec
sorting block 120, #reads = 1067977 mem = 536881180 peak = 1104535552
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 279142, 9, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 284, 559)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1381)
[M::mem_pestat] mean and std.dev: (370.05, 286.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1792)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 335, 468)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 976)
[M::mem_pestat] mean and std.dev: (350.47, 167.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1230)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (238, 327, 474)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 946)
[M::mem_pestat] mean and std.dev: (349.82, 155.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1182)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682946 reads in 269.645 CPU sec, 9.302 real sec
sorting block 121, #reads = 1067060 mem = 536879564 peak = 1143758848
[M::process] read 682132 sequences (100000225 bp) in 3.482 CPU sec, 3.784 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 278308, 9, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (142, 183, 294)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 598)
[M::mem_pestat] mean and std.dev: (221.36, 118.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 750)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 335, 469)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 981)
[M::mem_pestat] mean and std.dev: (350.89, 168.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1237)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 222, 581)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1399)
[M::mem_pestat] mean and std.dev: (233.90, 119.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1808)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 278459, 14, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (259, 350, 442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 808)
[M::mem_pestat] mean and std.dev: (337.66, 133.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 991)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 338, 473)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 987)
[M::mem_pestat] mean and std.dev: (354.04, 170.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1244)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 591, 2174)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6180)
[M::mem_pestat] mean and std.dev: (899.36, 915.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8183)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 208, 232)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 388)
[M::mem_pestat] mean and std.dev: (189.81, 50.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 466)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682784 reads in 524.325 CPU sec, 17.476 real sec
[M::mem_process_seqs] Processed 682316 reads in 194.462 CPU sec, 6.254 real sec
[M::process] read 681820 sequences (100000262 bp) in 3.069 CPU sec, 3.287 real sec...
sorting block 122, #reads = 1066732 mem = 536877027 peak = 1143758848
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 278023, 6, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 315, 451)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 959)
[M::mem_pestat] mean and std.dev: (308.54, 158.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1213)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 339, 475)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 991)
[M::mem_pestat] mean and std.dev: (355.50, 170.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1249)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (239, 352, 402)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 728)
[M::mem_pestat] mean and std.dev: (328.12, 145.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 908)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681972 sequences (100000088 bp) in 3.546 CPU sec, 3.804 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 278750, 13, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 304, 440)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 892)
[M::mem_pestat] mean and std.dev: (284.66, 112.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1118)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 340, 474)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 986)
[M::mem_pestat] mean and std.dev: (355.33, 169.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1242)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (289, 1071, 1653)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4381)
[M::mem_pestat] mean and std.dev: (852.77, 638.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5745)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (277, 360, 556)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1114)
[M::mem_pestat] mean and std.dev: (376.57, 166.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1393)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 681602 sequences (100000232 bp) in 2.433 CPU sec, 2.435 real sec...
[M::mem_process_seqs] Processed 682132 reads in 264.113 CPU sec, 8.427 real sec
[M::mem_process_seqs] Processed 681820 reads in 164.606 CPU sec, 5.217 real sec
sorting block 123, #reads = 1065881 mem = 536879818 peak = 1143758848
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 278257, 9, 24)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 302, 436)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 992)
[M::mem_pestat] mean and std.dev: (337.71, 225.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1270)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 338, 470)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 976)
[M::mem_pestat] mean and std.dev: (353.23, 168.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1229)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 301, 398)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 736)
[M::mem_pestat] mean and std.dev: (282.68, 122.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 905)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682040 sequences (100000141 bp) in 3.513 CPU sec, 3.805 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 277539, 4, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 278, 438)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 910)
[M::mem_pestat] mean and std.dev: (306.81, 172.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1146)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 338, 469)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 971)
[M::mem_pestat] mean and std.dev: (353.50, 167.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1222)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 322, 428)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 842)
[M::mem_pestat] mean and std.dev: (360.98, 186.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1108)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681742 sequences (100000236 bp) in 2.768 CPU sec, 2.771 real sec...
[M::mem_process_seqs] Processed 681972 reads in 266.064 CPU sec, 8.538 real sec
sorting block 124, #reads = 1065728 mem = 536884079 peak = 1143758848
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 277930, 7, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (255, 408, 674)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1512)
[M::mem_pestat] mean and std.dev: (504.30, 363.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1956)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 335, 465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 963)
[M::mem_pestat] mean and std.dev: (350.00, 165.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1212)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 357, 484)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1042)
[M::mem_pestat] mean and std.dev: (355.69, 168.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1321)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681888 sequences (100000205 bp) in 3.167 CPU sec, 3.168 real sec...
[M::mem_process_seqs] Processed 682040 reads in 146.264 CPU sec, 4.649 real sec
sorting block 125, #reads = 1064092 mem = 536881524 peak = 1143758848
[M::mem_process_seqs] Processed 681602 reads in 362.071 CPU sec, 11.516 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 277199, 18, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 210, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 677)
[M::mem_pestat] mean and std.dev: (265.22, 156.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 893)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 337, 468)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 968)
[M::mem_pestat] mean and std.dev: (352.19, 166.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1218)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (113, 727, 984)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2726)
[M::mem_pestat] mean and std.dev: (509.25, 391.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3597)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 311, 383)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 793)
[M::mem_pestat] mean and std.dev: (263.44, 117.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 998)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682368 sequences (100000050 bp) in 4.205 CPU sec, 4.437 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23, 277919, 9, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (228, 283, 588)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1308)
[M::mem_pestat] mean and std.dev: (351.65, 297.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1668)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 335, 468)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 972)
[M::mem_pestat] mean and std.dev: (351.02, 166.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1224)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 344, 419)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 803)
[M::mem_pestat] mean and std.dev: (338.83, 147.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 995)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681978 sequences (100000049 bp) in 2.330 CPU sec, 2.333 real sec...
[M::mem_process_seqs] Processed 681742 reads in 304.736 CPU sec, 9.719 real sec
sorting block 126, #reads = 1064709 mem = 536879788 peak = 1143758848
[M::mem_process_seqs] Processed 681888 reads in 170.122 CPU sec, 5.385 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 277670, 9, 22)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 264, 606)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1470)
[M::mem_pestat] mean and std.dev: (396.24, 314.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1902)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 332, 467)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 971)
[M::mem_pestat] mean and std.dev: (349.88, 167.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1223)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 352, 572)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1320)
[M::mem_pestat] mean and std.dev: (406.30, 274.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1694)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681850 sequences (100000024 bp) in 4.041 CPU sec, 4.409 real sec...
sorting block 127, #reads = 1063051 mem = 536878355 peak = 1143758848
[M::process] read 681934 sequences (100000296 bp) in 2.784 CPU sec, 2.786 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 278482, 4, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 296, 433)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 903)
[M::mem_pestat] mean and std.dev: (329.70, 171.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1138)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 335, 469)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 975)
[M::mem_pestat] mean and std.dev: (352.14, 168.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1228)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 292, 571)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1283)
[M::mem_pestat] mean and std.dev: (356.58, 189.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1639)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682368 reads in 274.020 CPU sec, 8.713 real sec
[M::mem_process_seqs] Processed 681978 reads in 165.308 CPU sec, 5.241 real sec
sorting block 128, #reads = 1062998 mem = 536880361 peak = 1143758848
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 278149, 11, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 244, 445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 965)
[M::mem_pestat] mean and std.dev: (295.37, 162.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1225)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 335, 469)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 975)
[M::mem_pestat] mean and std.dev: (352.66, 168.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1228)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (326, 944, 2747)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7589)
[M::mem_pestat] mean and std.dev: (1217.55, 1148.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10010)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (264, 374, 512)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1008)
[M::mem_pestat] mean and std.dev: (357.55, 132.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1256)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 681898 sequences (100000277 bp) in 3.953 CPU sec, 4.249 real sec...
[M::process] read 681894 sequences (100000057 bp) in 2.640 CPU sec, 2.644 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 277898, 5, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 304, 474)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1076)
[M::mem_pestat] mean and std.dev: (326.44, 192.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1377)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 336, 470)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 978)
[M::mem_pestat] mean and std.dev: (353.28, 170.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1232)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 278, 431)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 939)
[M::mem_pestat] mean and std.dev: (284.37, 140.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1193)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681850 reads in 275.533 CPU sec, 8.782 real sec
[M::mem_process_seqs] Processed 681934 reads in 168.086 CPU sec, 5.335 real sec
sorting block 129, #reads = 1063947 mem = 536878894 peak = 1143758848
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 278523, 15, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 217, 393)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 817)
[M::mem_pestat] mean and std.dev: (277.57, 141.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1029)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 336, 471)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 981)
[M::mem_pestat] mean and std.dev: (354.33, 171.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1236)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (337, 787, 1024)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2398)
[M::mem_pestat] mean and std.dev: (657.33, 455.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3085)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 417, 477)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 999)
[M::mem_pestat] mean and std.dev: (359.07, 181.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1260)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 687696 sequences (100000200 bp) in 3.709 CPU sec, 3.945 real sec...
[M::process] read 691156 sequences (100000207 bp) in 2.722 CPU sec, 2.732 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 277413, 12, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 262, 500)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1146)
[M::mem_pestat] mean and std.dev: (326.11, 219.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1469)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 336, 472)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 984)
[M::mem_pestat] mean and std.dev: (354.50, 172.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1240)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (372, 659, 1295)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3141)
[M::mem_pestat] mean and std.dev: (686.45, 603.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4064)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 355, 618)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1486)
[M::mem_pestat] mean and std.dev: (345.24, 219.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1920)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681898 reads in 287.858 CPU sec, 9.165 real sec
sorting block 130, #reads = 1062533 mem = 536881730 peak = 1143758848
[M::mem_process_seqs] Processed 681894 reads in 202.370 CPU sec, 6.462 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 280257, 7, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 304, 420)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 924)
[M::mem_pestat] mean and std.dev: (293.89, 126.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1176)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 300, 436)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 922)
[M::mem_pestat] mean and std.dev: (325.20, 163.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1165)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 238, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 735)
[M::mem_pestat] mean and std.dev: (256.45, 102.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 921)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 690580 sequences (100000221 bp) in 3.655 CPU sec, 3.933 real sec...
[M::process] read 688648 sequences (100000279 bp) in 2.699 CPU sec, 2.705 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (19, 281706, 4, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 266, 485)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1025)
[M::mem_pestat] mean and std.dev: (303.83, 152.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1295)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 284, 414)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 876)
[M::mem_pestat] mean and std.dev: (308.90, 155.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1107)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 252, 571)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1293)
[M::mem_pestat] mean and std.dev: (345.56, 195.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1654)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 687696 reads in 292.684 CPU sec, 9.326 real sec
sorting block 131, #reads = 1055782 mem = 536878172 peak = 1143758848
[M::mem_process_seqs] Processed 691156 reads in 184.683 CPU sec, 5.867 real sec
sorting block 132, #reads = 1058188 mem = 536883489 peak = 1143758848
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 281370, 11, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 267, 992)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2592)
[M::mem_pestat] mean and std.dev: (464.73, 467.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3392)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 287, 417)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 881)
[M::mem_pestat] mean and std.dev: (310.85, 155.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1113)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (26, 348, 425)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1223)
[M::mem_pestat] mean and std.dev: (236.60, 178.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1622)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 296, 541)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1275)
[M::mem_pestat] mean and std.dev: (323.39, 176.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1642)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 687258 sequences (100000280 bp) in 4.249 CPU sec, 4.575 real sec...
[M::process] read 686276 sequences (100000282 bp) in 2.680 CPU sec, 2.683 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 280867, 12, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 357, 470)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1016)
[M::mem_pestat] mean and std.dev: (320.24, 156.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1289)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 297, 426)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 896)
[M::mem_pestat] mean and std.dev: (317.70, 155.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1131)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (488, 1022, 1895)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4709)
[M::mem_pestat] mean and std.dev: (1171.83, 754.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6116)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (257, 447, 2868)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8090)
[M::mem_pestat] mean and std.dev: (1603.13, 2246.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10701)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 690580 reads in 286.545 CPU sec, 9.111 real sec
[M::mem_process_seqs] Processed 688648 reads in 177.737 CPU sec, 5.643 real sec
sorting block 133, #reads = 1060974 mem = 536880088 peak = 1143758848
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 280474, 11, 19)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 213, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 679)
[M::mem_pestat] mean and std.dev: (240.08, 117.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 854)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 304, 435)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 915)
[M::mem_pestat] mean and std.dev: (324.42, 158.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1155)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (336, 432, 1021)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2391)
[M::mem_pestat] mean and std.dev: (587.27, 466.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3076)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (267, 311, 398)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (5, 660)
[M::mem_pestat] mean and std.dev: (333.74, 131.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 861)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 685486 sequences (100000011 bp) in 4.023 CPU sec, 4.290 real sec...
[M::process] read 684486 sequences (100000021 bp) in 2.650 CPU sec, 2.656 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (21, 279956, 7, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 270, 441)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 983)
[M::mem_pestat] mean and std.dev: (270.17, 127.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1254)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 308, 439)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 921)
[M::mem_pestat] mean and std.dev: (327.81, 159.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1162)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 208, 268)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 478)
[M::mem_pestat] mean and std.dev: (187.61, 56.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 583)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 687258 reads in 278.033 CPU sec, 8.860 real sec
[M::mem_process_seqs] Processed 686276 reads in 169.602 CPU sec, 5.390 real sec
sorting block 134, #reads = 1063118 mem = 536881340 peak = 1143758848
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 280100, 4, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 278, 465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1097)
[M::mem_pestat] mean and std.dev: (383.39, 302.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1593)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 316, 446)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 934)
[M::mem_pestat] mean and std.dev: (333.91, 161.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1178)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (306, 390, 491)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 861)
[M::mem_pestat] mean and std.dev: (361.71, 135.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1046)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 684446 sequences (100000064 bp) in 4.404 CPU sec, 4.698 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 279854, 14, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 244, 345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 723)
[M::mem_pestat] mean and std.dev: (247.38, 116.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 912)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 320, 450)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 940)
[M::mem_pestat] mean and std.dev: (336.93, 162.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1185)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (33, 240, 376)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1062)
[M::mem_pestat] mean and std.dev: (210.25, 245.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1405)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 255, 483)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1057)
[M::mem_pestat] mean and std.dev: (251.06, 115.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1344)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 683770 sequences (100000185 bp) in 2.724 CPU sec, 2.732 real sec...
[M::mem_process_seqs] Processed 685486 reads in 274.543 CPU sec, 8.733 real sec
sorting block 135, #reads = 1063233 mem = 536878947 peak = 1143758848
[M::mem_process_seqs] Processed 684486 reads in 168.167 CPU sec, 5.326 real sec
sorting block 136, #reads = 1064335 mem = 536886169 peak = 1143758848
[M::process] read 683566 sequences (100000242 bp) in 3.939 CPU sec, 4.249 real sec...
[M::process] read 683706 sequences (100000037 bp) in 2.928 CPU sec, 2.931 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 279204, 8, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 247, 431)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 889)
[M::mem_pestat] mean and std.dev: (284.03, 123.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1118)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 326, 457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 953)
[M::mem_pestat] mean and std.dev: (342.41, 164.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1201)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 290, 385)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 777)
[M::mem_pestat] mean and std.dev: (279.91, 117.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 973)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683770 reads in 156.991 CPU sec, 4.955 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 279772, 8, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 303, 680)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1660)
[M::mem_pestat] mean and std.dev: (399.97, 294.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2150)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 322, 453)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 947)
[M::mem_pestat] mean and std.dev: (339.11, 163.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1194)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (239, 274, 521)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1085)
[M::mem_pestat] mean and std.dev: (331.52, 160.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1367)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 278264, 11, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 295, 514)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1134)
[M::mem_pestat] mean and std.dev: (345.98, 222.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1444)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 329, 461)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 963)
[M::mem_pestat] mean and std.dev: (345.25, 165.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1214)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (129, 430, 1740)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4962)
[M::mem_pestat] mean and std.dev: (808.60, 1117.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6573)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (293, 352, 464)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 806)
[M::mem_pestat] mean and std.dev: (353.70, 124.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 977)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 683822 sequences (100000245 bp) in 3.406 CPU sec, 3.423 real sec...
[M::mem_process_seqs] Processed 684446 reads in 444.667 CPU sec, 14.161 real sec
sorting block 137, #reads = 1063931 mem = 536885697 peak = 1143758848
[M::mem_process_seqs] Processed 683566 reads in 209.214 CPU sec, 6.674 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 278363, 14, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 260, 288)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 514)
[M::mem_pestat] mean and std.dev: (227.50, 78.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 627)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 329, 464)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 972)
[M::mem_pestat] mean and std.dev: (346.58, 167.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1226)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (8, 788, 3842)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 11510)
[M::mem_pestat] mean and std.dev: (1572.36, 1843.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 15344)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 270, 407)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 845)
[M::mem_pestat] mean and std.dev: (302.48, 143.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1064)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 683314 sequences (100000212 bp) in 4.568 CPU sec, 4.911 real sec...
sorting block 138, #reads = 1062138 mem = 536878939 peak = 1143758848
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 278592, 6, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 324, 392)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 838)
[M::mem_pestat] mean and std.dev: (279.64, 126.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1061)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 329, 465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 977)
[M::mem_pestat] mean and std.dev: (346.50, 167.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1233)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 342, 529)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1099)
[M::mem_pestat] mean and std.dev: (406.38, 260.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1448)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683706 reads in 316.396 CPU sec, 10.104 real sec
[M::mem_process_seqs] Processed 683822 reads in 200.108 CPU sec, 6.329 real sec
[M::process] read 683060 sequences (100000043 bp) in 4.095 CPU sec, 4.228 real sec...
sorting block 139, #reads = 1061932 mem = 536883477 peak = 1143758848
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 278306, 6, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 277, 463)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1001)
[M::mem_pestat] mean and std.dev: (346.24, 199.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1270)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 328, 463)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 967)
[M::mem_pestat] mean and std.dev: (346.43, 166.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1219)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 272, 466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 962)
[M::mem_pestat] mean and std.dev: (267.23, 108.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1210)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682884 sequences (100000178 bp) in 4.584 CPU sec, 5.026 real sec...
[M::process] read 682976 sequences (100000100 bp) in 3.266 CPU sec, 3.266 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 278953, 10, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (233, 339, 448)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 878)
[M::mem_pestat] mean and std.dev: (322.38, 141.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1093)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 328, 462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 966)
[M::mem_pestat] mean and std.dev: (345.94, 166.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1218)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (29, 318, 1209)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3569)
[M::mem_pestat] mean and std.dev: (717.30, 845.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4749)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 230, 352)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 734)
[M::mem_pestat] mean and std.dev: (213.67, 85.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 925)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683314 reads in 323.536 CPU sec, 10.299 real sec
[M::mem_process_seqs] Processed 683060 reads in 196.515 CPU sec, 6.235 real sec
sorting block 140, #reads = 1062751 mem = 536878621 peak = 1143758848
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 278473, 13, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 253, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 622)
[M::mem_pestat] mean and std.dev: (241.59, 93.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 765)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 330, 465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 971)
[M::mem_pestat] mean and std.dev: (348.34, 168.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1224)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (323, 398, 885)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2009)
[M::mem_pestat] mean and std.dev: (556.54, 401.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2571)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (289, 336, 772)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1738)
[M::mem_pestat] mean and std.dev: (435.02, 267.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2221)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 683250 sequences (100000166 bp) in 5.796 CPU sec, 6.166 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 278984, 8, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 229, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 655)
[M::mem_pestat] mean and std.dev: (257.24, 143.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 830)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 329, 466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 976)
[M::mem_pestat] mean and std.dev: (348.32, 168.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1231)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (250, 360, 546)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1138)
[M::mem_pestat] mean and std.dev: (382.00, 195.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1434)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682884 reads in 309.641 CPU sec, 9.876 real sec
[M::mem_process_seqs] Processed 682976 reads in 189.929 CPU sec, 5.994 real sec
sorting block 141, #reads = 1064826 mem = 536879976 peak = 1143758848
[M::process] read 682206 sequences (100000123 bp) in 4.119 CPU sec, 4.321 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 278272, 18, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 249, 289)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 561)
[M::mem_pestat] mean and std.dev: (247.40, 109.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 697)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 328, 464)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 972)
[M::mem_pestat] mean and std.dev: (347.04, 169.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1226)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (106, 372, 591)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1561)
[M::mem_pestat] mean and std.dev: (379.67, 286.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2046)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 295, 388)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 750)
[M::mem_pestat] mean and std.dev: (290.08, 108.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 931)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682544 sequences (100000034 bp) in 4.143 CPU sec, 4.551 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 278011, 13, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 246, 292)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 556)
[M::mem_pestat] mean and std.dev: (215.32, 69.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 688)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 333, 471)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 985)
[M::mem_pestat] mean and std.dev: (352.25, 170.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1242)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (483, 795, 2806)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7452)
[M::mem_pestat] mean and std.dev: (1444.62, 1072.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9775)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 293, 401)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 827)
[M::mem_pestat] mean and std.dev: (323.00, 160.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1040)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682496 sequences (100000086 bp) in 3.106 CPU sec, 3.113 real sec...
[M::mem_process_seqs] Processed 683250 reads in 322.664 CPU sec, 10.284 real sec
sorting block 142, #reads = 1064570 mem = 536880788 peak = 1143758848
[M::mem_process_seqs] Processed 682206 reads in 190.816 CPU sec, 6.024 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 278533, 9, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 223, 458)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 994)
[M::mem_pestat] mean and std.dev: (305.48, 194.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1262)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 333, 467)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 973)
[M::mem_pestat] mean and std.dev: (350.55, 169.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1226)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 280, 407)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 771)
[M::mem_pestat] mean and std.dev: (292.19, 98.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 953)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 143, #reads = 1064756 mem = 536876942 peak = 1143758848
[M::process] read 682026 sequences (100000079 bp) in 5.477 CPU sec, 5.832 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 278080, 8, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 303, 444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 956)
[M::mem_pestat] mean and std.dev: (289.35, 135.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1212)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 331, 465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 969)
[M::mem_pestat] mean and std.dev: (349.24, 168.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1221)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 345, 533)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1167)
[M::mem_pestat] mean and std.dev: (326.90, 149.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1484)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682544 reads in 310.476 CPU sec, 9.936 real sec
[M::mem_process_seqs] Processed 682496 reads in 181.639 CPU sec, 5.751 real sec
[M::process] read 681944 sequences (100000233 bp) in 3.747 CPU sec, 3.980 real sec...
sorting block 144, #reads = 1065140 mem = 536877641 peak = 1143758848
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 278127, 10, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 350, 794)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1986)
[M::mem_pestat] mean and std.dev: (501.43, 486.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2582)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 335, 471)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 981)
[M::mem_pestat] mean and std.dev: (353.60, 170.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1236)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (29, 641, 8190)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 24512)
[M::mem_pestat] mean and std.dev: (2967.90, 3982.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 32673)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (299, 426, 642)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1328)
[M::mem_pestat] mean and std.dev: (464.07, 259.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1671)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 681554 sequences (100000066 bp) in 4.643 CPU sec, 4.979 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 277676, 18, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 345, 426)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 856)
[M::mem_pestat] mean and std.dev: (314.30, 142.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1071)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 335, 471)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 981)
[M::mem_pestat] mean and std.dev: (354.22, 171.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1236)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (444, 774, 807)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1533)
[M::mem_pestat] mean and std.dev: (587.38, 411.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2233)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 335, 426)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 892)
[M::mem_pestat] mean and std.dev: (326.07, 133.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1125)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682026 reads in 315.249 CPU sec, 10.035 real sec
[M::process] read 681234 sequences (100000077 bp) in 3.555 CPU sec, 3.591 real sec...
[M::mem_process_seqs] Processed 681944 reads in 186.446 CPU sec, 5.871 real sec
sorting block 145, #reads = 1065892 mem = 536877884 peak = 1143758848
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 278161, 8, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 344, 669)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1573)
[M::mem_pestat] mean and std.dev: (412.87, 248.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2025)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 339, 475)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 989)
[M::mem_pestat] mean and std.dev: (357.04, 172.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1246)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 406, 1126)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2970)
[M::mem_pestat] mean and std.dev: (481.65, 469.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3892)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681354 sequences (100000282 bp) in 5.933 CPU sec, 6.382 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 277672, 2, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (223, 365, 857)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2125)
[M::mem_pestat] mean and std.dev: (427.05, 372.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2759)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 341, 478)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 994)
[M::mem_pestat] mean and std.dev: (359.75, 174.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1252)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 298, 417)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 797)
[M::mem_pestat] mean and std.dev: (283.29, 110.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 987)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681554 reads in 314.450 CPU sec, 10.053 real sec
[M::mem_process_seqs] Processed 681234 reads in 187.496 CPU sec, 5.929 real sec
sorting block 146, #reads = 1066167 mem = 536876683 peak = 1143758848
[M::process] read 445540 sequences (65325861 bp) in 2.728 CPU sec, 2.810 real sec...
sorting block 147, #reads = 1066677 mem = 536877356 peak = 1143758848
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 277386, 9, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 259, 1260)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3412)
[M::mem_pestat] mean and std.dev: (662.18, 611.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4488)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 342, 481)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1003)
[M::mem_pestat] mean and std.dev: (361.24, 175.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1264)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 324, 483)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1053)
[M::mem_pestat] mean and std.dev: (305.39, 145.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1338)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681354 reads in 174.565 CPU sec, 5.756 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (21, 181944, 4, 19)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 208, 268)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (19, 434)
[M::mem_pestat] mean and std.dev: (211.78, 63.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 517)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 338, 477)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 997)
[M::mem_pestat] mean and std.dev: (357.74, 175.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1257)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 227, 410)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 928)
[M::mem_pestat] mean and std.dev: (229.69, 115.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1187)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 445540 reads in 142.896 CPU sec, 5.021 real sec
sorting block 148, #reads = 1066363 mem = 536884587 peak = 1143758848
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000a06d1
  features: 1f8bfbff fffab20b
  extended: f1bf27eb 1b407f7e
  amd bits: 2c100800 00000121
     brand: Intel(R) Xeon(R) 6975P-C
threads: 31
algo: bwa-mem
license: sentieon:klib=31
reads: 158068218
overall: 70176976896 mem 39881.109 user 1239.704 sys 1343.359 real
[main] Version: 0.7.17-r1188
[main] CMD: /opt/conda/share/sentieon-202308.03-3/libexec/bwa mem -K 100000000 -Y -R @RG\tID:A23MHWWLT4.1029_FZX-T1-TDNA-1_A23MHWWLT4_1.L003\tPU:L003\tSM:1029_FZX-T1-TDNA-1_A23MHWWLT4_1\tLB:1029_FZX-T1-TDNA-1_A23MHWWLT4_1\tDS:s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta\tPL:ILLUMINA -t 31 ./BWAIndex/Homo_sapiens_assembly38.fasta.64 1029_FZX-T1-TDNA-1_A23MHWWLT4_1_R1.fastq.gz 1029_FZX-T1-TDNA-1_A23MHWWLT4_1_R2.fastq.gz
[main] Real time: 1343.398 sec; CPU: 41120.815 sec
sorting block 149, #reads = 228090 mem = 115499947 peak = 1143758848
uniq header count 1
merging 150 blocks
sw version: sentieon-genomics-202308.03
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000a06d1
  features: 1f8bfbff fffab20b
  extended: f1bf27eb 1b407f7e
  amd bits: 2c100800 00000121
     brand: Intel(R) Xeon(R) 6975P-C
threads: 31 max 192
algo: util-sort
license: sentieon:util=1
output file size: 8958047773
output reads: 159198510
bam_mem_sort: 150 calls 132.431 user 3.064 sys 136.435 real
bam_write: 150 calls 99.716 user 5.305 sys 144.240 real
execute: 1 calls 52.712 user 2.676 sys 1405.769 real
merge_files: 1 calls 52.690 user 2.583 sys 62.146 real
parse_chunk: 2388 calls 120.190 user 35.141 sys 169.375 real
read_chunk: 6447 calls 63.933 user 36.879 sys 1065.870 real
sort_block: 1 calls 43.117 user 36.122 sys 1036.846 real
write_chunk: 4057 calls 52.271 user 2.176 sys 61.041 real
overall: 3440386048 mem 2228.330 user 114.152 sys 1405.794 real
ls: cannot access '*.cram': No such file or directory