This software is licensed to bgold@natera.com by Sentieon Inc.
cmdline: /opt/conda/share/sentieon-202308.03-3/libexec/util sort -r Homo_sapiens_assembly38.fasta -t 31 -o 1136_27F-T1-TDNA-1_A23MHWWLT4_1.bam --sam2bam -
This software is licensed to bgold@natera.com by Sentieon Inc.
version: sentieon-genomics-202308.03
[M::bwa_idx_load_from_disk] read 3171 ALT contigs
[M::main_mem] bwa index loaded in 2161.370 CPU sec, 98.539 real sec
[M::process] read 701470 sequences (100000191 bp) in 1.236 CPU sec, 1.248 real sec...
[M::process] read 699304 sequences (100000009 bp) in 1.529 CPU sec, 1.563 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 292305, 31, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 289, 604)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1406)
[M::mem_pestat] mean and std.dev: (308.47, 220.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1807)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 234, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 704)
[M::mem_pestat] mean and std.dev: (258.58, 128.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 886)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (319, 533, 1217)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3013)
[M::mem_pestat] mean and std.dev: (758.63, 643.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3911)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 258, 457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1003)
[M::mem_pestat] mean and std.dev: (286.56, 158.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1276)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698438 sequences (100000144 bp) in 1.585 CPU sec, 1.636 real sec...
[M::process] read 697948 sequences (100000262 bp) in 1.629 CPU sec, 1.654 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 291566, 18, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 255, 779)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1995)
[M::mem_pestat] mean and std.dev: (455.75, 498.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2603)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 240, 349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 725)
[M::mem_pestat] mean and std.dev: (264.89, 132.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 913)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 923, 1234)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3334)
[M::mem_pestat] mean and std.dev: (611.93, 542.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4384)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 234, 530)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1246)
[M::mem_pestat] mean and std.dev: (288.34, 175.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1604)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701470 reads in 178.971 CPU sec, 6.002 real sec
[M::mem_process_seqs] Processed 699304 reads in 115.233 CPU sec, 4.132 real sec
sorting block 0, #reads = 1090874 mem = 536878534 peak = 560324608
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 291486, 27, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (257, 357, 801)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1889)
[M::mem_pestat] mean and std.dev: (444.86, 313.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2433)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 244, 354)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 738)
[M::mem_pestat] mean and std.dev: (268.62, 134.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 930)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (104, 459, 637)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1703)
[M::mem_pestat] mean and std.dev: (360.22, 249.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2236)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 350, 875)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2239)
[M::mem_pestat] mean and std.dev: (509.37, 433.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2921)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696712 sequences (100000095 bp) in 2.317 CPU sec, 2.588 real sec...
[M::process] read 696344 sequences (100000179 bp) in 1.732 CPU sec, 1.819 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 291012, 30, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 259, 523)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1253)
[M::mem_pestat] mean and std.dev: (335.06, 275.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1618)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 246, 357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 745)
[M::mem_pestat] mean and std.dev: (271.01, 136.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 939)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 690, 1389)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3845)
[M::mem_pestat] mean and std.dev: (733.54, 601.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5073)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 295, 997)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2665)
[M::mem_pestat] mean and std.dev: (483.54, 596.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3499)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698438 reads in 183.019 CPU sec, 6.632 real sec
[M::mem_process_seqs] Processed 697948 reads in 118.896 CPU sec, 4.346 real sec
sorting block 1, #reads = 1090986 mem = 536879442 peak = 686153728
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 290682, 18, 84)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 300, 478)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1006)
[M::mem_pestat] mean and std.dev: (296.63, 156.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1270)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 248, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 750)
[M::mem_pestat] mean and std.dev: (272.98, 136.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 945)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 506, 1271)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3427)
[M::mem_pestat] mean and std.dev: (977.78, 940.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4741)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 300, 410)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 856)
[M::mem_pestat] mean and std.dev: (299.25, 142.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1079)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696934 sequences (100000002 bp) in 2.076 CPU sec, 2.392 real sec...
[M::process] read 696350 sequences (100000237 bp) in 1.860 CPU sec, 1.946 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 290617, 33, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 262, 652)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1534)
[M::mem_pestat] mean and std.dev: (393.30, 311.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1975)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 248, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 745)
[M::mem_pestat] mean and std.dev: (273.00, 136.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 938)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (312, 387, 710)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1506)
[M::mem_pestat] mean and std.dev: (391.54, 212.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1904)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 301, 582)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1380)
[M::mem_pestat] mean and std.dev: (353.71, 253.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1779)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696712 reads in 186.603 CPU sec, 6.641 real sec
[M::mem_process_seqs] Processed 696344 reads in 119.035 CPU sec, 4.216 real sec
sorting block 2, #reads = 1089026 mem = 536878755 peak = 788430848
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (83, 290434, 27, 73)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 353, 817)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2029)
[M::mem_pestat] mean and std.dev: (513.48, 491.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2635)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 246, 357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 743)
[M::mem_pestat] mean and std.dev: (270.99, 135.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 936)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 547, 1128)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2976)
[M::mem_pestat] mean and std.dev: (602.96, 474.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3900)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 317, 537)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1209)
[M::mem_pestat] mean and std.dev: (348.23, 215.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1545)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695668 sequences (100000027 bp) in 2.526 CPU sec, 2.928 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 290387, 24, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 249, 423)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 965)
[M::mem_pestat] mean and std.dev: (274.62, 160.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1236)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 247, 357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 741)
[M::mem_pestat] mean and std.dev: (271.96, 135.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 933)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (271, 815, 1947)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5299)
[M::mem_pestat] mean and std.dev: (1109.39, 1039.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6975)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 316, 788)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2028)
[M::mem_pestat] mean and std.dev: (546.94, 520.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2648)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694640 sequences (100000281 bp) in 1.760 CPU sec, 1.790 real sec...
[M::mem_process_seqs] Processed 696934 reads in 192.279 CPU sec, 7.038 real sec
sorting block 3, #reads = 1088167 mem = 536878580 peak = 788430848
[M::mem_process_seqs] Processed 696350 reads in 123.285 CPU sec, 4.506 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (91, 289842, 29, 80)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 287, 827)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2125)
[M::mem_pestat] mean and std.dev: (463.72, 456.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2774)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 249, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 746)
[M::mem_pestat] mean and std.dev: (273.59, 135.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 939)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (343, 1029, 1597)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4105)
[M::mem_pestat] mean and std.dev: (1073.32, 840.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5359)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 413, 732)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1806)
[M::mem_pestat] mean and std.dev: (469.13, 340.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2343)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694314 sequences (100000055 bp) in 2.124 CPU sec, 2.535 real sec...
sorting block 4, #reads = 1087975 mem = 536880019 peak = 822947840
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (87, 289396, 21, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 295, 1050)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2814)
[M::mem_pestat] mean and std.dev: (584.19, 690.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3696)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 254, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 754)
[M::mem_pestat] mean and std.dev: (276.56, 136.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 949)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 430, 1344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3622)
[M::mem_pestat] mean and std.dev: (855.71, 826.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4761)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 230, 447)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1009)
[M::mem_pestat] mean and std.dev: (293.57, 196.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1290)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 693788 sequences (100000285 bp) in 1.862 CPU sec, 1.983 real sec...
[M::mem_process_seqs] Processed 695668 reads in 193.248 CPU sec, 7.133 real sec
[M::process] read 698166 sequences (100000248 bp) in 2.181 CPU sec, 2.199 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 289898, 26, 76)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 518, 1284)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3536)
[M::mem_pestat] mean and std.dev: (729.88, 719.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4662)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 257, 369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 765)
[M::mem_pestat] mean and std.dev: (280.36, 138.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 963)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (607, 740, 1447)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3127)
[M::mem_pestat] mean and std.dev: (913.21, 615.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3967)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 242, 597)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1441)
[M::mem_pestat] mean and std.dev: (367.59, 292.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1863)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 693788 reads in 110.350 CPU sec, 4.216 real sec
sorting block 5, #reads = 1087463 mem = 536878099 peak = 822947840
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 290058, 26, 90)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 292, 530)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1282)
[M::mem_pestat] mean and std.dev: (302.77, 176.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1658)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 254, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 748)
[M::mem_pestat] mean and std.dev: (275.81, 134.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 941)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (262, 761, 1601)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4279)
[M::mem_pestat] mean and std.dev: (866.50, 751.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5618)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 247, 398)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 854)
[M::mem_pestat] mean and std.dev: (260.75, 148.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1082)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 694314 reads in 216.347 CPU sec, 8.808 real sec
[M::process] read 700034 sequences (100000045 bp) in 2.045 CPU sec, 2.205 real sec...
sorting block 6, #reads = 1087962 mem = 536879064 peak = 858640384
[M::mem_process_seqs] Processed 694640 reads in 406.922 CPU sec, 15.658 real sec
[M::process] read 698424 sequences (100000166 bp) in 2.462 CPU sec, 2.696 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 291895, 20, 75)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 367, 584)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1344)
[M::mem_pestat] mean and std.dev: (416.63, 321.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1724)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 239, 350)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 732)
[M::mem_pestat] mean and std.dev: (265.20, 133.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 923)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (307, 513, 702)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1492)
[M::mem_pestat] mean and std.dev: (478.11, 302.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1887)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 317, 813)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2007)
[M::mem_pestat] mean and std.dev: (456.69, 410.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2604)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700034 reads in 100.262 CPU sec, 3.240 real sec
sorting block 7, #reads = 1087975 mem = 536877917 peak = 858640384
[M::process] read 697682 sequences (100000234 bp) in 2.103 CPU sec, 2.180 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 291391, 33, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 256, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 586)
[M::mem_pestat] mean and std.dev: (261.80, 117.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 734)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 244, 352)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 732)
[M::mem_pestat] mean and std.dev: (267.71, 133.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 922)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (268, 427, 1635)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4369)
[M::mem_pestat] mean and std.dev: (1057.42, 1172.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5746)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 228, 431)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 949)
[M::mem_pestat] mean and std.dev: (277.06, 168.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1208)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (74, 291583, 28, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 300, 507)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1175)
[M::mem_pestat] mean and std.dev: (347.99, 250.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1509)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 244, 355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 741)
[M::mem_pestat] mean and std.dev: (269.11, 135.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 934)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 417, 900)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2390)
[M::mem_pestat] mean and std.dev: (577.48, 459.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3135)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 343, 489)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1013)
[M::mem_pestat] mean and std.dev: (335.37, 169.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1275)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698166 reads in 301.459 CPU sec, 10.053 real sec
[M::mem_process_seqs] Processed 698424 reads in 133.654 CPU sec, 4.372 real sec
[M::process] read 697012 sequences (100000168 bp) in 2.289 CPU sec, 2.428 real sec...
sorting block 8, #reads = 1091252 mem = 536880738 peak = 858640384
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (76, 291060, 17, 75)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 268, 735)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1863)
[M::mem_pestat] mean and std.dev: (412.60, 389.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2427)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 246, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 751)
[M::mem_pestat] mean and std.dev: (271.86, 137.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 947)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (296, 417, 1493)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3887)
[M::mem_pestat] mean and std.dev: (897.82, 887.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5084)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 289, 483)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1107)
[M::mem_pestat] mean and std.dev: (279.20, 148.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1419)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696572 sequences (100000278 bp) in 2.667 CPU sec, 2.833 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (77, 290648, 23, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 299, 437)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 961)
[M::mem_pestat] mean and std.dev: (285.16, 150.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1223)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 248, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 756)
[M::mem_pestat] mean and std.dev: (273.74, 137.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 953)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (134, 917, 2557)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7403)
[M::mem_pestat] mean and std.dev: (1715.48, 2139.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10273)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 297, 374)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 766)
[M::mem_pestat] mean and std.dev: (271.33, 128.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 962)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697682 reads in 181.413 CPU sec, 6.021 real sec
[M::process] read 696778 sequences (100000275 bp) in 1.932 CPU sec, 2.022 real sec...
sorting block 9, #reads = 1090533 mem = 536876502 peak = 858640384
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (78, 290746, 15, 72)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 272, 699)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1763)
[M::mem_pestat] mean and std.dev: (373.78, 382.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2295)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 248, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 756)
[M::mem_pestat] mean and std.dev: (274.29, 138.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 953)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (310, 715, 1251)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3133)
[M::mem_pestat] mean and std.dev: (782.73, 517.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4074)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 303, 667)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1597)
[M::mem_pestat] mean and std.dev: (411.29, 327.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2062)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697250 sequences (100000104 bp) in 2.152 CPU sec, 2.217 real sec...
[M::mem_process_seqs] Processed 696572 reads in 104.889 CPU sec, 3.579 real sec
[M::mem_process_seqs] Processed 697012 reads in 264.815 CPU sec, 8.881 real sec
sorting block 10, #reads = 1089469 mem = 536881025 peak = 858640384
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 290669, 26, 94)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 232, 653)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1653)
[M::mem_pestat] mean and std.dev: (296.68, 250.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2153)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 247, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 746)
[M::mem_pestat] mean and std.dev: (272.03, 136.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 940)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 482, 818)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2116)
[M::mem_pestat] mean and std.dev: (486.71, 410.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2765)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 316, 482)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1086)
[M::mem_pestat] mean and std.dev: (310.41, 168.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1388)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696296 sequences (100000275 bp) in 2.509 CPU sec, 2.952 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 290508, 25, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 265, 1055)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2817)
[M::mem_pestat] mean and std.dev: (610.47, 586.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3698)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 246, 356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 740)
[M::mem_pestat] mean and std.dev: (271.01, 136.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 932)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (71, 433, 687)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1919)
[M::mem_pestat] mean and std.dev: (391.26, 330.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2535)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 297, 481)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1067)
[M::mem_pestat] mean and std.dev: (331.33, 218.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1360)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696778 reads in 199.032 CPU sec, 6.611 real sec
[M::mem_process_seqs] Processed 697250 reads in 118.983 CPU sec, 3.954 real sec
sorting block 11, #reads = 1088894 mem = 536884373 peak = 858640384
[M::process] read 696156 sequences (100000218 bp) in 2.387 CPU sec, 2.532 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 290147, 21, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 309, 1129)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3017)
[M::mem_pestat] mean and std.dev: (570.51, 584.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3961)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 247, 357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 741)
[M::mem_pestat] mean and std.dev: (271.63, 135.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 933)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 277, 630)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1468)
[M::mem_pestat] mean and std.dev: (342.70, 205.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1887)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 313, 504)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1060)
[M::mem_pestat] mean and std.dev: (339.12, 166.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1338)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695362 sequences (100000299 bp) in 2.087 CPU sec, 2.412 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 290371, 26, 72)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 371, 797)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1969)
[M::mem_pestat] mean and std.dev: (465.26, 322.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2555)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 248, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 745)
[M::mem_pestat] mean and std.dev: (272.85, 135.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 938)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (99, 601, 1036)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2910)
[M::mem_pestat] mean and std.dev: (605.88, 648.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3847)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (253, 379, 592)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1270)
[M::mem_pestat] mean and std.dev: (413.32, 263.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1609)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696296 reads in 191.599 CPU sec, 6.314 real sec
[M::process] read 694580 sequences (100000172 bp) in 1.861 CPU sec, 1.907 real sec...
sorting block 12, #reads = 1088065 mem = 536878143 peak = 858640384
[M::mem_process_seqs] Processed 696156 reads in 123.609 CPU sec, 3.995 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (80, 290325, 28, 74)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 357, 1045)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2795)
[M::mem_pestat] mean and std.dev: (501.78, 540.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3670)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 251, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 755)
[M::mem_pestat] mean and std.dev: (275.46, 137.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 951)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 394, 1142)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3088)
[M::mem_pestat] mean and std.dev: (539.63, 455.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4061)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 330, 841)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2121)
[M::mem_pestat] mean and std.dev: (465.37, 406.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2761)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 13, #reads = 1087951 mem = 536879197 peak = 883621888
[M::process] read 695840 sequences (100000020 bp) in 2.739 CPU sec, 3.031 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 290094, 34, 75)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 275, 416)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 910)
[M::mem_pestat] mean and std.dev: (269.82, 164.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1157)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 254, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 754)
[M::mem_pestat] mean and std.dev: (276.82, 136.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 949)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (241, 457, 744)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1750)
[M::mem_pestat] mean and std.dev: (390.60, 259.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2253)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 290, 690)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1706)
[M::mem_pestat] mean and std.dev: (448.51, 421.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2214)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695362 reads in 183.948 CPU sec, 6.096 real sec
[M::process] read 700918 sequences (100000050 bp) in 2.064 CPU sec, 2.176 real sec...
[M::mem_process_seqs] Processed 694580 reads in 118.352 CPU sec, 3.919 real sec
sorting block 14, #reads = 1087257 mem = 536879523 peak = 883621888
[M::process] read 698942 sequences (100000142 bp) in 2.544 CPU sec, 2.860 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 292264, 27, 79)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (133, 300, 630)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1624)
[M::mem_pestat] mean and std.dev: (346.26, 278.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2121)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 236, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 710)
[M::mem_pestat] mean and std.dev: (260.55, 130.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 894)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (117, 608, 1497)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4257)
[M::mem_pestat] mean and std.dev: (834.62, 940.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5637)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 280, 683)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1677)
[M::mem_pestat] mean and std.dev: (364.18, 260.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2174)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700918 reads in 106.470 CPU sec, 3.507 real sec
[M::process] read 697934 sequences (100000220 bp) in 2.282 CPU sec, 2.362 real sec...
sorting block 15, #reads = 1089205 mem = 536880624 peak = 883621888
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 289812, 20, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 401, 1747)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4853)
[M::mem_pestat] mean and std.dev: (848.23, 996.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6406)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 250, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 754)
[M::mem_pestat] mean and std.dev: (274.98, 137.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 950)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 336, 1062)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2780)
[M::mem_pestat] mean and std.dev: (513.16, 451.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3639)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 237, 401)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 849)
[M::mem_pestat] mean and std.dev: (255.39, 127.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1073)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 291591, 19, 79)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 275, 483)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1109)
[M::mem_pestat] mean and std.dev: (313.06, 210.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1422)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 242, 351)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 731)
[M::mem_pestat] mean and std.dev: (266.70, 133.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 921)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 537, 1201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3263)
[M::mem_pestat] mean and std.dev: (714.37, 646.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4294)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 280, 610)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1454)
[M::mem_pestat] mean and std.dev: (365.92, 248.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1876)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695840 reads in 289.334 CPU sec, 9.612 real sec
[M::mem_process_seqs] Processed 698942 reads in 138.740 CPU sec, 4.619 real sec
[M::process] read 697150 sequences (100000256 bp) in 2.695 CPU sec, 2.886 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 291361, 18, 78)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 304, 581)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1367)
[M::mem_pestat] mean and std.dev: (331.09, 234.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1760)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 245, 354)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 736)
[M::mem_pestat] mean and std.dev: (268.96, 133.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 927)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 459, 1029)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2643)
[M::mem_pestat] mean and std.dev: (481.80, 463.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3450)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 264, 815)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2083)
[M::mem_pestat] mean and std.dev: (418.47, 387.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2717)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 16, #reads = 1087109 mem = 536881098 peak = 883621888
[M::process] read 696338 sequences (100000022 bp) in 2.732 CPU sec, 3.239 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 291041, 31, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 215, 701)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1785)
[M::mem_pestat] mean and std.dev: (391.00, 344.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2327)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 248, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 749)
[M::mem_pestat] mean and std.dev: (272.23, 135.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 944)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (443, 899, 1808)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4538)
[M::mem_pestat] mean and std.dev: (1079.30, 790.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5903)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 392, 1164)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3132)
[M::mem_pestat] mean and std.dev: (641.45, 762.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4116)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697934 reads in 185.532 CPU sec, 6.118 real sec
[M::mem_process_seqs] Processed 697150 reads in 120.564 CPU sec, 3.999 real sec
[M::process] read 696184 sequences (100000219 bp) in 2.459 CPU sec, 2.721 real sec...
sorting block 17, #reads = 1091029 mem = 536876719 peak = 883621888
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 290634, 19, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 292, 672)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1600)
[M::mem_pestat] mean and std.dev: (343.43, 240.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2064)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 250, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 757)
[M::mem_pestat] mean and std.dev: (275.06, 137.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 954)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (311, 805, 3348)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9422)
[M::mem_pestat] mean and std.dev: (2344.21, 2867.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13816)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 295, 550)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1258)
[M::mem_pestat] mean and std.dev: (320.60, 198.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1612)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696360 sequences (100000284 bp) in 2.284 CPU sec, 2.563 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 290248, 42, 76)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 230, 477)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1109)
[M::mem_pestat] mean and std.dev: (279.70, 200.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1425)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 249, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 754)
[M::mem_pestat] mean and std.dev: (274.77, 137.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 950)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (240, 579, 1091)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2793)
[M::mem_pestat] mean and std.dev: (728.33, 622.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3644)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 331, 560)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1320)
[M::mem_pestat] mean and std.dev: (371.42, 249.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1700)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696338 reads in 183.627 CPU sec, 6.062 real sec
[M::mem_process_seqs] Processed 696184 reads in 120.006 CPU sec, 3.929 real sec
sorting block 18, #reads = 1088610 mem = 536883491 peak = 883621888
[M::process] read 696164 sequences (100000119 bp) in 2.577 CPU sec, 2.774 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 290430, 27, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 267, 824)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2136)
[M::mem_pestat] mean and std.dev: (412.16, 415.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2792)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 248, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 747)
[M::mem_pestat] mean and std.dev: (272.74, 136.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 941)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (535, 832, 3165)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8425)
[M::mem_pestat] mean and std.dev: (1500.20, 1607.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11055)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 285, 399)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 819)
[M::mem_pestat] mean and std.dev: (298.02, 175.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1029)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695754 sequences (100000220 bp) in 2.645 CPU sec, 2.944 real sec...
sorting block 19, #reads = 1087763 mem = 536878685 peak = 883621888
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 289952, 50, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 323, 545)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1291)
[M::mem_pestat] mean and std.dev: (381.59, 283.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1664)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 248, 357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 739)
[M::mem_pestat] mean and std.dev: (271.91, 135.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 930)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (252, 653, 1541)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4119)
[M::mem_pestat] mean and std.dev: (647.31, 660.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5408)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 301, 766)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1876)
[M::mem_pestat] mean and std.dev: (384.59, 269.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2431)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696360 reads in 186.888 CPU sec, 6.137 real sec
[M::mem_process_seqs] Processed 696164 reads in 120.089 CPU sec, 3.934 real sec
[M::process] read 695620 sequences (100000085 bp) in 2.290 CPU sec, 2.440 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (73, 290610, 25, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 271, 753)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1917)
[M::mem_pestat] mean and std.dev: (394.06, 406.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2499)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 249, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 749)
[M::mem_pestat] mean and std.dev: (274.00, 136.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 943)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (243, 469, 980)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2454)
[M::mem_pestat] mean and std.dev: (623.08, 493.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3191)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 322, 599)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1357)
[M::mem_pestat] mean and std.dev: (391.48, 250.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1736)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 20, #reads = 1087422 mem = 536878801 peak = 883621888
[M::process] read 694524 sequences (100000281 bp) in 2.270 CPU sec, 2.676 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 290095, 21, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 241, 368)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 810)
[M::mem_pestat] mean and std.dev: (222.66, 98.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1031)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 249, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 752)
[M::mem_pestat] mean and std.dev: (274.65, 137.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 947)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (250, 1092, 5685)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 16555)
[M::mem_pestat] mean and std.dev: (2017.43, 2397.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 21990)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 274, 488)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1112)
[M::mem_pestat] mean and std.dev: (327.48, 212.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1424)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695754 reads in 182.446 CPU sec, 6.024 real sec
[M::mem_process_seqs] Processed 695620 reads in 118.479 CPU sec, 3.855 real sec
[M::process] read 693920 sequences (100000013 bp) in 2.507 CPU sec, 2.800 real sec...
sorting block 21, #reads = 1088855 mem = 536878739 peak = 883621888
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 289244, 28, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 328, 819)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2085)
[M::mem_pestat] mean and std.dev: (428.77, 410.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2718)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 254, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 760)
[M::mem_pestat] mean and std.dev: (278.26, 138.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 957)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 649, 1684)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4652)
[M::mem_pestat] mean and std.dev: (1035.86, 1154.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6136)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 248, 577)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1407)
[M::mem_pestat] mean and std.dev: (337.67, 292.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1822)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700694 sequences (100000071 bp) in 2.596 CPU sec, 3.055 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 289680, 34, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 299, 683)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1709)
[M::mem_pestat] mean and std.dev: (399.55, 338.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2222)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 256, 368)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 764)
[M::mem_pestat] mean and std.dev: (279.99, 138.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 962)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 404, 983)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2515)
[M::mem_pestat] mean and std.dev: (472.90, 449.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3281)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 282, 512)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1166)
[M::mem_pestat] mean and std.dev: (295.11, 159.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1493)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 694524 reads in 185.848 CPU sec, 6.073 real sec
[M::mem_process_seqs] Processed 693920 reads in 119.086 CPU sec, 3.894 real sec
[M::process] read 699998 sequences (100000028 bp) in 2.325 CPU sec, 2.499 real sec...
sorting block 22, #reads = 1086979 mem = 536878382 peak = 883621888
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 292141, 26, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 267, 654)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1576)
[M::mem_pestat] mean and std.dev: (308.15, 244.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2037)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 236, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 716)
[M::mem_pestat] mean and std.dev: (261.80, 132.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 902)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (265, 484, 1072)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2686)
[M::mem_pestat] mean and std.dev: (618.68, 528.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3493)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 252, 581)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1409)
[M::mem_pestat] mean and std.dev: (363.60, 312.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1823)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698686 sequences (100000002 bp) in 2.366 CPU sec, 3.061 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (76, 292515, 30, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 345, 864)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2188)
[M::mem_pestat] mean and std.dev: (518.84, 490.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2850)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 239, 349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 729)
[M::mem_pestat] mean and std.dev: (265.13, 134.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 919)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (324, 809, 1063)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2541)
[M::mem_pestat] mean and std.dev: (817.14, 651.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3421)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (231, 276, 424)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 810)
[M::mem_pestat] mean and std.dev: (284.15, 110.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1003)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700694 reads in 188.082 CPU sec, 6.316 real sec
[M::mem_process_seqs] Processed 699998 reads in 119.886 CPU sec, 4.061 real sec
sorting block 23, #reads = 1086517 mem = 536880328 peak = 883621888
[M::process] read 698040 sequences (100000035 bp) in 2.288 CPU sec, 2.542 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 291060, 28, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 350, 718)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1734)
[M::mem_pestat] mean and std.dev: (438.37, 338.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2242)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 242, 353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 737)
[M::mem_pestat] mean and std.dev: (267.93, 135.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 929)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (474, 1132, 3247)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8793)
[M::mem_pestat] mean and std.dev: (1947.07, 1947.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11566)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 272, 676)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1696)
[M::mem_pestat] mean and std.dev: (423.36, 370.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2206)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698216 sequences (100000038 bp) in 2.705 CPU sec, 3.113 real sec...
sorting block 24, #reads = 1091880 mem = 536881689 peak = 893943808
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 291027, 20, 77)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 445, 884)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2190)
[M::mem_pestat] mean and std.dev: (585.25, 570.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2868)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 245, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 748)
[M::mem_pestat] mean and std.dev: (271.18, 137.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 943)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (144, 318, 516)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1260)
[M::mem_pestat] mean and std.dev: (295.17, 208.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1632)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 332, 503)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1117)
[M::mem_pestat] mean and std.dev: (333.97, 173.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1424)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698686 reads in 186.879 CPU sec, 6.131 real sec
[M::mem_process_seqs] Processed 698040 reads in 119.525 CPU sec, 3.891 real sec
[M::process] read 696714 sequences (100000135 bp) in 2.479 CPU sec, 2.701 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (74, 291026, 34, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 266, 759)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1977)
[M::mem_pestat] mean and std.dev: (376.43, 404.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2586)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 245, 356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 742)
[M::mem_pestat] mean and std.dev: (270.13, 136.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 935)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (41, 668, 1273)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3737)
[M::mem_pestat] mean and std.dev: (999.26, 1171.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5685)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 405, 1249)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3367)
[M::mem_pestat] mean and std.dev: (569.93, 616.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4426)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 25, #reads = 1090345 mem = 536880934 peak = 893943808
[M::process] read 696718 sequences (100000154 bp) in 2.386 CPU sec, 2.881 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 290898, 22, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 347, 913)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2411)
[M::mem_pestat] mean and std.dev: (531.70, 536.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3160)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 248, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 753)
[M::mem_pestat] mean and std.dev: (273.65, 137.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 949)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (106, 476, 675)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1813)
[M::mem_pestat] mean and std.dev: (419.70, 329.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2382)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 354, 549)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1259)
[M::mem_pestat] mean and std.dev: (378.36, 282.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1614)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698216 reads in 185.027 CPU sec, 6.115 real sec
[M::mem_process_seqs] Processed 696714 reads in 119.266 CPU sec, 3.903 real sec
[M::process] read 696444 sequences (100000044 bp) in 2.545 CPU sec, 2.784 real sec...
sorting block 26, #reads = 1090338 mem = 536878334 peak = 893943808
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 290291, 22, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 278, 484)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1078)
[M::mem_pestat] mean and std.dev: (329.27, 218.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1375)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 247, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 744)
[M::mem_pestat] mean and std.dev: (271.87, 135.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 937)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 822, 1723)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4847)
[M::mem_pestat] mean and std.dev: (1138.73, 1231.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6409)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 304, 542)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1230)
[M::mem_pestat] mean and std.dev: (377.57, 283.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1574)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696088 sequences (100000239 bp) in 2.518 CPU sec, 3.027 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 290067, 39, 85)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 222, 388)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 836)
[M::mem_pestat] mean and std.dev: (279.95, 175.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1060)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 247, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 744)
[M::mem_pestat] mean and std.dev: (272.31, 136.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 937)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 314, 663)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1665)
[M::mem_pestat] mean and std.dev: (364.53, 312.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2166)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 320, 538)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1170)
[M::mem_pestat] mean and std.dev: (332.67, 201.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1486)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696718 reads in 184.638 CPU sec, 6.128 real sec
[M::mem_process_seqs] Processed 696444 reads in 118.713 CPU sec, 3.924 real sec
sorting block 27, #reads = 1089460 mem = 536877748 peak = 893943808
[M::process] read 695262 sequences (100000288 bp) in 2.489 CPU sec, 2.741 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 290180, 38, 76)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 293, 479)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1119)
[M::mem_pestat] mean and std.dev: (330.64, 255.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1439)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 247, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 747)
[M::mem_pestat] mean and std.dev: (272.65, 136.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 941)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (145, 781, 1669)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4717)
[M::mem_pestat] mean and std.dev: (979.39, 925.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6241)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 367, 1107)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2901)
[M::mem_pestat] mean and std.dev: (669.20, 645.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3798)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694768 sequences (100000150 bp) in 2.332 CPU sec, 2.590 real sec...
sorting block 28, #reads = 1087784 mem = 536878223 peak = 893943808
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 290317, 25, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 303, 467)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1019)
[M::mem_pestat] mean and std.dev: (324.13, 200.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1295)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 250, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 749)
[M::mem_pestat] mean and std.dev: (274.60, 135.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 943)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (73, 867, 1865)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5449)
[M::mem_pestat] mean and std.dev: (1314.44, 1493.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7287)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 340, 723)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1725)
[M::mem_pestat] mean and std.dev: (464.83, 357.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2226)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696088 reads in 185.548 CPU sec, 6.082 real sec
[M::mem_process_seqs] Processed 695262 reads in 121.385 CPU sec, 3.941 real sec
[M::process] read 694350 sequences (100000291 bp) in 2.568 CPU sec, 2.780 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 289888, 13, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 243, 978)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2566)
[M::mem_pestat] mean and std.dev: (512.65, 513.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3360)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 252, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 745)
[M::mem_pestat] mean and std.dev: (274.73, 134.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 937)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (52, 216, 1362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3982)
[M::mem_pestat] mean and std.dev: (411.82, 473.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5292)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 356, 604)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1376)
[M::mem_pestat] mean and std.dev: (415.54, 301.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1762)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 29, #reads = 1087561 mem = 536878035 peak = 893943808
[M::process] read 702342 sequences (100000179 bp) in 2.665 CPU sec, 3.115 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (99, 289984, 32, 77)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 241, 496)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1086)
[M::mem_pestat] mean and std.dev: (344.16, 239.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1381)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 255, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 761)
[M::mem_pestat] mean and std.dev: (278.54, 137.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 958)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (52, 174, 1078)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3130)
[M::mem_pestat] mean and std.dev: (516.78, 616.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4156)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 352, 604)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1414)
[M::mem_pestat] mean and std.dev: (405.12, 292.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1819)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 694768 reads in 180.369 CPU sec, 5.915 real sec
[M::mem_process_seqs] Processed 694350 reads in 116.893 CPU sec, 3.798 real sec
[M::process] read 703408 sequences (100000080 bp) in 2.477 CPU sec, 2.789 real sec...
sorting block 30, #reads = 1086301 mem = 536881510 peak = 893943808
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 293201, 27, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 350, 563)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1275)
[M::mem_pestat] mean and std.dev: (416.86, 302.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1631)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 230, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 707)
[M::mem_pestat] mean and std.dev: (257.93, 131.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 891)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 508, 1203)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3211)
[M::mem_pestat] mean and std.dev: (754.56, 690.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4215)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 303, 513)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1157)
[M::mem_pestat] mean and std.dev: (347.31, 223.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1479)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701690 sequences (100000042 bp) in 2.406 CPU sec, 2.875 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 293606, 32, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 288, 529)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1253)
[M::mem_pestat] mean and std.dev: (321.00, 217.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1615)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 227, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 700)
[M::mem_pestat] mean and std.dev: (255.63, 131.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 882)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 582, 1594)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4488)
[M::mem_pestat] mean and std.dev: (738.68, 921.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5935)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (142, 235, 385)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 871)
[M::mem_pestat] mean and std.dev: (253.19, 147.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1114)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702342 reads in 191.963 CPU sec, 6.294 real sec
[M::mem_process_seqs] Processed 703408 reads in 123.057 CPU sec, 4.005 real sec
[M::process] read 700494 sequences (100000123 bp) in 2.534 CPU sec, 2.768 real sec...
sorting block 31, #reads = 1088023 mem = 536878192 peak = 893943808
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 292824, 23, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 273, 648)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1626)
[M::mem_pestat] mean and std.dev: (402.10, 357.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2115)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 233, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 715)
[M::mem_pestat] mean and std.dev: (260.72, 133.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 901)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (421, 582, 1256)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2926)
[M::mem_pestat] mean and std.dev: (775.81, 518.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3761)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 331, 719)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1723)
[M::mem_pestat] mean and std.dev: (401.47, 300.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2225)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699374 sequences (100000118 bp) in 2.546 CPU sec, 3.004 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 292288, 31, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 298, 860)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2228)
[M::mem_pestat] mean and std.dev: (407.64, 353.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2912)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 236, 349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 731)
[M::mem_pestat] mean and std.dev: (264.67, 135.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 922)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (232, 420, 746)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1774)
[M::mem_pestat] mean and std.dev: (463.83, 362.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2288)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 299, 512)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1112)
[M::mem_pestat] mean and std.dev: (348.24, 211.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1412)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701690 reads in 198.432 CPU sec, 6.518 real sec
sorting block 32, #reads = 1093038 mem = 536880937 peak = 919928832
[M::process] read 698414 sequences (100000085 bp) in 2.398 CPU sec, 2.711 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 292187, 26, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 293, 488)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1112)
[M::mem_pestat] mean and std.dev: (301.83, 167.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1424)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 240, 355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 745)
[M::mem_pestat] mean and std.dev: (268.79, 138.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 940)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 764, 1448)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3960)
[M::mem_pestat] mean and std.dev: (985.77, 944.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5216)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 342, 605)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1471)
[M::mem_pestat] mean and std.dev: (400.89, 345.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1904)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699374 reads in 105.782 CPU sec, 3.605 real sec
[M::process] read 697840 sequences (100000244 bp) in 2.256 CPU sec, 2.758 real sec...
sorting block 33, #reads = 1090313 mem = 536881212 peak = 919928832
[M::mem_process_seqs] Processed 700494 reads in 301.754 CPU sec, 10.011 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 290956, 37, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 257, 479)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1095)
[M::mem_pestat] mean and std.dev: (312.66, 224.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1403)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 243, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 750)
[M::mem_pestat] mean and std.dev: (270.95, 138.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 946)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 662, 1130)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3030)
[M::mem_pestat] mean and std.dev: (657.50, 547.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3980)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 286, 472)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1038)
[M::mem_pestat] mean and std.dev: (315.17, 169.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1321)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (82, 291396, 32, 73)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 247, 416)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 902)
[M::mem_pestat] mean and std.dev: (284.37, 164.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1145)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 244, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 748)
[M::mem_pestat] mean and std.dev: (271.23, 137.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 943)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 644, 1505)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4177)
[M::mem_pestat] mean and std.dev: (848.70, 906.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5513)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 312, 946)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2390)
[M::mem_pestat] mean and std.dev: (541.16, 537.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3112)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697360 sequences (100000273 bp) in 2.729 CPU sec, 3.588 real sec...
[M::mem_process_seqs] Processed 698414 reads in 215.726 CPU sec, 7.171 real sec
[M::mem_process_seqs] Processed 697840 reads in 125.488 CPU sec, 4.237 real sec
sorting block 34, #reads = 1088333 mem = 536878575 peak = 919928832
[M::process] read 696910 sequences (100000123 bp) in 2.406 CPU sec, 2.811 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (76, 291217, 31, 73)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 240, 496)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1190)
[M::mem_pestat] mean and std.dev: (272.36, 218.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1537)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 245, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 751)
[M::mem_pestat] mean and std.dev: (272.16, 138.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 947)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 588, 959)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2445)
[M::mem_pestat] mean and std.dev: (641.28, 523.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3188)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 281, 500)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1146)
[M::mem_pestat] mean and std.dev: (309.39, 216.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1469)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 35, #reads = 1087172 mem = 536879594 peak = 923906048
[M::process] read 696512 sequences (100000247 bp) in 2.400 CPU sec, 2.901 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 290302, 27, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 229, 533)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1303)
[M::mem_pestat] mean and std.dev: (296.33, 251.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1688)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 246, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 752)
[M::mem_pestat] mean and std.dev: (272.96, 137.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 948)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (490, 650, 1353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3079)
[M::mem_pestat] mean and std.dev: (774.40, 614.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3942)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 308, 949)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2425)
[M::mem_pestat] mean and std.dev: (515.59, 431.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3163)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697360 reads in 196.749 CPU sec, 6.482 real sec
[M::mem_process_seqs] Processed 696910 reads in 128.330 CPU sec, 4.364 real sec
[M::process] read 696376 sequences (100000058 bp) in 1.878 CPU sec, 2.081 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 290805, 29, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 278, 532)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1284)
[M::mem_pestat] mean and std.dev: (317.83, 277.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1660)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 247, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 747)
[M::mem_pestat] mean and std.dev: (272.49, 136.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 941)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (269, 646, 1680)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4502)
[M::mem_pestat] mean and std.dev: (827.15, 780.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5913)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 309, 1073)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2811)
[M::mem_pestat] mean and std.dev: (550.52, 546.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3680)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 36, #reads = 1086721 mem = 536878463 peak = 923906048
[M::process] read 697486 sequences (100000082 bp) in 2.871 CPU sec, 3.233 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (74, 290396, 19, 85)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 264, 798)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2058)
[M::mem_pestat] mean and std.dev: (446.10, 428.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2688)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 247, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 744)
[M::mem_pestat] mean and std.dev: (272.18, 135.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 937)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 371, 957)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2523)
[M::mem_pestat] mean and std.dev: (569.37, 521.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3306)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 339, 681)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1633)
[M::mem_pestat] mean and std.dev: (398.90, 286.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2109)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696512 reads in 194.973 CPU sec, 6.437 real sec
[M::mem_process_seqs] Processed 696376 reads in 123.938 CPU sec, 4.006 real sec
[M::process] read 706488 sequences (100000175 bp) in 2.179 CPU sec, 2.375 real sec...
sorting block 37, #reads = 1085292 mem = 536879171 peak = 923906048
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 290837, 16, 78)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 286, 540)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1224)
[M::mem_pestat] mean and std.dev: (352.57, 222.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1566)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 244, 356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 742)
[M::mem_pestat] mean and std.dev: (270.08, 136.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 935)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 746, 1184)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3258)
[M::mem_pestat] mean and std.dev: (684.87, 669.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4295)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 335, 603)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1405)
[M::mem_pestat] mean and std.dev: (396.07, 286.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1806)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703346 sequences (100000009 bp) in 2.588 CPU sec, 3.003 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 294378, 14, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 292, 642)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1606)
[M::mem_pestat] mean and std.dev: (427.39, 371.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2088)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 219, 320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 660)
[M::mem_pestat] mean and std.dev: (244.96, 123.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 830)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (529, 1017, 1482)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3388)
[M::mem_pestat] mean and std.dev: (908.25, 476.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4341)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 319, 569)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1319)
[M::mem_pestat] mean and std.dev: (373.35, 270.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1694)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697486 reads in 201.987 CPU sec, 6.673 real sec
[M::mem_process_seqs] Processed 706488 reads in 129.381 CPU sec, 4.228 real sec
[M::process] read 703386 sequences (100000204 bp) in 2.019 CPU sec, 2.179 real sec...
sorting block 38, #reads = 1085501 mem = 536878291 peak = 923906048
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 293396, 27, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 319, 816)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2060)
[M::mem_pestat] mean and std.dev: (336.63, 238.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2682)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 227, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 696)
[M::mem_pestat] mean and std.dev: (254.30, 129.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 877)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (322, 773, 1854)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4918)
[M::mem_pestat] mean and std.dev: (1012.72, 1005.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6450)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 352, 574)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1328)
[M::mem_pestat] mean and std.dev: (409.43, 307.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1705)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 39, #reads = 1088183 mem = 536880161 peak = 923906048
[M::process] read 701682 sequences (100000246 bp) in 3.384 CPU sec, 3.831 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 293813, 21, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 296, 884)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2332)
[M::mem_pestat] mean and std.dev: (538.79, 577.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3056)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 227, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 694)
[M::mem_pestat] mean and std.dev: (254.70, 129.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 874)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (347, 575, 951)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2159)
[M::mem_pestat] mean and std.dev: (565.16, 405.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2763)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 500, 987)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2557)
[M::mem_pestat] mean and std.dev: (647.53, 608.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3342)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703346 reads in 202.635 CPU sec, 6.633 real sec
[M::process] read 700670 sequences (100000297 bp) in 2.139 CPU sec, 2.181 real sec...
[M::mem_process_seqs] Processed 703386 reads in 128.847 CPU sec, 4.192 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 293149, 26, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 289, 671)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1577)
[M::mem_pestat] mean and std.dev: (393.41, 295.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2030)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 233, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 717)
[M::mem_pestat] mean and std.dev: (260.48, 132.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 904)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 525, 1071)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2801)
[M::mem_pestat] mean and std.dev: (547.42, 431.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3666)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (139, 269, 998)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2716)
[M::mem_pestat] mean and std.dev: (519.34, 567.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3575)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 40, #reads = 1088754 mem = 536879687 peak = 923906048
[M::process] read 699304 sequences (100000285 bp) in 2.878 CPU sec, 3.221 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 292518, 20, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 346, 1141)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3015)
[M::mem_pestat] mean and std.dev: (715.94, 729.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3952)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 236, 348)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 728)
[M::mem_pestat] mean and std.dev: (263.52, 134.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 918)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (135, 429, 994)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2712)
[M::mem_pestat] mean and std.dev: (601.25, 575.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3571)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 350, 637)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1461)
[M::mem_pestat] mean and std.dev: (428.94, 319.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1873)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701682 reads in 198.571 CPU sec, 6.483 real sec
[M::process] read 698428 sequences (100000234 bp) in 1.816 CPU sec, 1.926 real sec...
sorting block 41, #reads = 1088427 mem = 536877094 peak = 923906048
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (78, 291943, 36, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 298, 841)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2171)
[M::mem_pestat] mean and std.dev: (507.57, 534.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2836)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 240, 353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 739)
[M::mem_pestat] mean and std.dev: (267.68, 136.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 932)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (311, 451, 1131)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2771)
[M::mem_pestat] mean and std.dev: (568.18, 421.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3591)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 282, 472)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1030)
[M::mem_pestat] mean and std.dev: (306.32, 203.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1309)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699304 reads in 109.373 CPU sec, 3.797 real sec
[M::process] read 697718 sequences (100000024 bp) in 2.329 CPU sec, 2.452 real sec...
[M::mem_process_seqs] Processed 700670 reads in 284.033 CPU sec, 9.470 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 291975, 29, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 377, 565)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1287)
[M::mem_pestat] mean and std.dev: (404.73, 247.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1648)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 241, 356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 744)
[M::mem_pestat] mean and std.dev: (269.78, 137.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 938)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 361, 1233)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3237)
[M::mem_pestat] mean and std.dev: (506.40, 459.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4239)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 319, 577)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1275)
[M::mem_pestat] mean and std.dev: (359.50, 218.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1624)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 42, #reads = 1087335 mem = 536878855 peak = 923906048
[M::process] read 697020 sequences (100000197 bp) in 2.392 CPU sec, 2.833 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (85, 291082, 25, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 351, 604)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1420)
[M::mem_pestat] mean and std.dev: (367.71, 252.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1828)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 244, 357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 745)
[M::mem_pestat] mean and std.dev: (271.27, 137.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 939)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (133, 269, 1307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3655)
[M::mem_pestat] mean and std.dev: (492.45, 691.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4829)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 251, 428)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 946)
[M::mem_pestat] mean and std.dev: (248.65, 130.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1205)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698428 reads in 215.233 CPU sec, 7.010 real sec
[M::mem_process_seqs] Processed 697718 reads in 127.057 CPU sec, 4.145 real sec
[M::process] read 696644 sequences (100000090 bp) in 2.616 CPU sec, 2.830 real sec...
sorting block 43, #reads = 1086076 mem = 536879631 peak = 923906048
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 290609, 21, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 290, 544)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1316)
[M::mem_pestat] mean and std.dev: (278.49, 170.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1702)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 245, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 749)
[M::mem_pestat] mean and std.dev: (272.38, 138.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 944)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (365, 857, 1304)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3182)
[M::mem_pestat] mean and std.dev: (760.11, 511.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4121)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (230, 325, 700)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1640)
[M::mem_pestat] mean and std.dev: (450.87, 331.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2110)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697610 sequences (100000256 bp) in 2.239 CPU sec, 2.701 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (76, 290996, 16, 82)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 393, 1211)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3199)
[M::mem_pestat] mean and std.dev: (704.07, 687.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4193)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 246, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 756)
[M::mem_pestat] mean and std.dev: (274.33, 139.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 953)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (284, 811, 1356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3500)
[M::mem_pestat] mean and std.dev: (706.43, 637.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4572)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (235, 329, 618)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1384)
[M::mem_pestat] mean and std.dev: (393.11, 238.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1767)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697020 reads in 190.836 CPU sec, 6.245 real sec
[M::mem_process_seqs] Processed 696644 reads in 125.770 CPU sec, 4.096 real sec
[M::process] read 704100 sequences (100000006 bp) in 2.685 CPU sec, 2.880 real sec...
sorting block 44, #reads = 1086313 mem = 536880237 peak = 923906048
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (87, 291017, 30, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 270, 508)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1174)
[M::mem_pestat] mean and std.dev: (318.21, 218.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1507)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 242, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 751)
[M::mem_pestat] mean and std.dev: (272.12, 140.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 947)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (405, 958, 1228)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2874)
[M::mem_pestat] mean and std.dev: (843.59, 527.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3697)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 282, 578)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1386)
[M::mem_pestat] mean and std.dev: (368.90, 315.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1790)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701772 sequences (100000202 bp) in 2.430 CPU sec, 3.121 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 293371, 21, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 312, 587)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1405)
[M::mem_pestat] mean and std.dev: (361.59, 279.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1814)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 225, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 684)
[M::mem_pestat] mean and std.dev: (252.04, 128.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 861)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (144, 320, 1090)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2982)
[M::mem_pestat] mean and std.dev: (494.85, 473.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3928)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 276, 454)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1002)
[M::mem_pestat] mean and std.dev: (287.29, 165.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1276)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697610 reads in 202.546 CPU sec, 6.635 real sec
sorting block 45, #reads = 1086257 mem = 536880022 peak = 944160768
[M::mem_process_seqs] Processed 704100 reads in 126.390 CPU sec, 4.136 real sec
[M::process] read 701010 sequences (100000281 bp) in 2.160 CPU sec, 2.258 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 293053, 23, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 258, 784)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1986)
[M::mem_pestat] mean and std.dev: (457.06, 427.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2587)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 232, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 708)
[M::mem_pestat] mean and std.dev: (258.73, 130.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 892)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (419, 584, 1239)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2879)
[M::mem_pestat] mean and std.dev: (854.91, 739.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3812)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 294, 610)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1406)
[M::mem_pestat] mean and std.dev: (337.12, 222.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1804)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 46, #reads = 1086060 mem = 536879042 peak = 988905472
[M::process] read 700046 sequences (100000091 bp) in 2.441 CPU sec, 2.900 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 292348, 14, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 246, 410)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 934)
[M::mem_pestat] mean and std.dev: (276.06, 177.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1196)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 234, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 715)
[M::mem_pestat] mean and std.dev: (260.72, 132.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 901)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (271, 544, 1655)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4423)
[M::mem_pestat] mean and std.dev: (448.27, 449.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5807)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 313, 683)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1627)
[M::mem_pestat] mean and std.dev: (423.55, 324.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2099)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701772 reads in 183.585 CPU sec, 6.082 real sec
[M::mem_process_seqs] Processed 701010 reads in 119.936 CPU sec, 3.936 real sec
[M::process] read 699838 sequences (100000151 bp) in 2.135 CPU sec, 2.304 real sec...
sorting block 47, #reads = 1091526 mem = 536881582 peak = 988905472
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 292496, 14, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (255, 366, 455)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 855)
[M::mem_pestat] mean and std.dev: (341.23, 142.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1055)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 237, 349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 729)
[M::mem_pestat] mean and std.dev: (264.82, 135.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 919)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (278, 908, 958)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2318)
[M::mem_pestat] mean and std.dev: (594.00, 413.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2998)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 285, 555)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1275)
[M::mem_pestat] mean and std.dev: (344.81, 222.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1635)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699154 sequences (100000144 bp) in 2.675 CPU sec, 3.057 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 292162, 21, 72)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 303, 503)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1127)
[M::mem_pestat] mean and std.dev: (357.29, 221.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1439)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 238, 351)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 735)
[M::mem_pestat] mean and std.dev: (265.95, 135.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 927)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (446, 667, 1655)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4073)
[M::mem_pestat] mean and std.dev: (970.33, 906.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5282)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (232, 327, 924)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2308)
[M::mem_pestat] mean and std.dev: (550.52, 466.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3000)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700046 reads in 189.091 CPU sec, 6.217 real sec
[M::mem_process_seqs] Processed 699838 reads in 125.117 CPU sec, 4.068 real sec
[M::process] read 697702 sequences (100000055 bp) in 2.258 CPU sec, 2.498 real sec...
sorting block 48, #reads = 1089338 mem = 536879950 peak = 988905472
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 291911, 24, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 228, 494)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1146)
[M::mem_pestat] mean and std.dev: (346.75, 254.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1472)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 240, 354)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 742)
[M::mem_pestat] mean and std.dev: (267.84, 136.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 936)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 493, 3247)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9415)
[M::mem_pestat] mean and std.dev: (1511.04, 1910.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12499)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 338, 704)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1720)
[M::mem_pestat] mean and std.dev: (407.74, 319.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2228)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697434 sequences (100000198 bp) in 2.569 CPU sec, 2.813 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 290905, 34, 80)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 267, 458)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1032)
[M::mem_pestat] mean and std.dev: (285.93, 154.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1319)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 244, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 748)
[M::mem_pestat] mean and std.dev: (271.21, 137.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 943)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 663, 1342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3658)
[M::mem_pestat] mean and std.dev: (744.97, 710.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4816)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 405, 702)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1744)
[M::mem_pestat] mean and std.dev: (433.23, 329.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2265)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699154 reads in 188.610 CPU sec, 6.111 real sec
[M::process] read 697356 sequences (100000255 bp) in 1.865 CPU sec, 1.886 real sec...
sorting block 49, #reads = 1088520 mem = 536878523 peak = 988905472
[M::mem_process_seqs] Processed 697702 reads in 122.995 CPU sec, 3.935 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 290924, 27, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 257, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 769)
[M::mem_pestat] mean and std.dev: (258.22, 154.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 974)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 244, 357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 745)
[M::mem_pestat] mean and std.dev: (270.99, 137.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 939)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (317, 721, 1438)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3680)
[M::mem_pestat] mean and std.dev: (589.77, 466.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4801)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 342, 958)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2518)
[M::mem_pestat] mean and std.dev: (540.55, 541.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3298)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 50, #reads = 1087095 mem = 536880011 peak = 988905472
[M::process] read 696978 sequences (100000107 bp) in 2.968 CPU sec, 3.191 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 290632, 27, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 344, 537)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1197)
[M::mem_pestat] mean and std.dev: (330.08, 189.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1527)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 243, 355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 739)
[M::mem_pestat] mean and std.dev: (269.89, 136.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 931)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (114, 409, 1413)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4011)
[M::mem_pestat] mean and std.dev: (487.82, 570.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5310)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 263, 485)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1107)
[M::mem_pestat] mean and std.dev: (309.00, 186.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1418)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696914 sequences (100000054 bp) in 1.914 CPU sec, 1.928 real sec...
[M::mem_process_seqs] Processed 697434 reads in 189.455 CPU sec, 6.082 real sec
[M::mem_process_seqs] Processed 697356 reads in 123.448 CPU sec, 3.942 real sec
sorting block 51, #reads = 1086091 mem = 536882650 peak = 988905472
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (73, 290830, 32, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 288, 670)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1678)
[M::mem_pestat] mean and std.dev: (359.21, 316.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2182)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 244, 357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 743)
[M::mem_pestat] mean and std.dev: (271.35, 137.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 936)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (132, 607, 979)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2673)
[M::mem_pestat] mean and std.dev: (595.90, 571.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3520)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 274, 564)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1338)
[M::mem_pestat] mean and std.dev: (330.74, 262.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1725)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705006 sequences (100000127 bp) in 2.624 CPU sec, 2.764 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (77, 290383, 25, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 290, 811)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1995)
[M::mem_pestat] mean and std.dev: (497.44, 449.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2587)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 244, 357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 743)
[M::mem_pestat] mean and std.dev: (271.66, 138.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 936)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (277, 547, 1353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3505)
[M::mem_pestat] mean and std.dev: (764.88, 657.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4581)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 242, 516)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1178)
[M::mem_pestat] mean and std.dev: (318.55, 225.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1509)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705338 sequences (100000122 bp) in 1.904 CPU sec, 1.912 real sec...
[M::mem_process_seqs] Processed 696978 reads in 192.125 CPU sec, 6.150 real sec
[M::mem_process_seqs] Processed 696914 reads in 122.956 CPU sec, 3.908 real sec
sorting block 52, #reads = 1083671 mem = 536878815 peak = 988905472
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 293232, 34, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (137, 230, 500)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1226)
[M::mem_pestat] mean and std.dev: (269.71, 220.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1589)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 222, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 670)
[M::mem_pestat] mean and std.dev: (248.55, 125.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 843)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (72, 544, 1373)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3975)
[M::mem_pestat] mean and std.dev: (780.66, 873.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5276)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 385, 1115)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2939)
[M::mem_pestat] mean and std.dev: (533.37, 589.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3851)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704820 sequences (100000035 bp) in 2.963 CPU sec, 3.122 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 294005, 27, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 217, 382)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 820)
[M::mem_pestat] mean and std.dev: (240.92, 146.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1039)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 222, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 670)
[M::mem_pestat] mean and std.dev: (248.39, 125.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 843)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (310, 459, 990)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2350)
[M::mem_pestat] mean and std.dev: (516.08, 378.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3030)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (259, 330, 741)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1705)
[M::mem_pestat] mean and std.dev: (453.46, 298.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2187)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703772 sequences (100000242 bp) in 1.650 CPU sec, 1.656 real sec...
[M::mem_process_seqs] Processed 705006 reads in 178.121 CPU sec, 5.657 real sec
[M::mem_process_seqs] Processed 705338 reads in 104.281 CPU sec, 3.297 real sec
sorting block 53, #reads = 1079915 mem = 536879012 peak = 988905472
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 293978, 21, 76)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 306, 662)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1632)
[M::mem_pestat] mean and std.dev: (398.29, 309.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2117)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 222, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 676)
[M::mem_pestat] mean and std.dev: (249.17, 126.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 851)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 646, 2229)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6239)
[M::mem_pestat] mean and std.dev: (1282.05, 1649.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8244)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 289, 978)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2504)
[M::mem_pestat] mean and std.dev: (544.24, 536.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3267)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702432 sequences (100000001 bp) in 2.574 CPU sec, 2.682 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 293644, 29, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 361, 837)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2133)
[M::mem_pestat] mean and std.dev: (395.20, 311.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2781)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 224, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 681)
[M::mem_pestat] mean and std.dev: (251.46, 127.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 857)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (271, 760, 2221)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6121)
[M::mem_pestat] mean and std.dev: (1302.07, 1523.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8071)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 213, 525)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1259)
[M::mem_pestat] mean and std.dev: (299.76, 228.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1626)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700230 sequences (100000036 bp) in 1.900 CPU sec, 1.898 real sec...
[M::mem_process_seqs] Processed 704820 reads in 169.901 CPU sec, 5.394 real sec
sorting block 54, #reads = 1088797 mem = 536880098 peak = 988905472
[M::process] read 698726 sequences (100000237 bp) in 1.790 CPU sec, 1.795 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 293378, 22, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 230, 455)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1039)
[M::mem_pestat] mean and std.dev: (287.17, 167.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1331)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 230, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 704)
[M::mem_pestat] mean and std.dev: (257.73, 131.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 887)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 851, 1785)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4989)
[M::mem_pestat] mean and std.dev: (1038.59, 870.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6591)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 294, 461)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1037)
[M::mem_pestat] mean and std.dev: (303.08, 193.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1325)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702432 reads in 105.575 CPU sec, 3.584 real sec
sorting block 55, #reads = 1088072 mem = 536879936 peak = 1044783104
[M::mem_process_seqs] Processed 703772 reads in 251.541 CPU sec, 8.215 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 292182, 24, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 311, 633)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1521)
[M::mem_pestat] mean and std.dev: (408.78, 329.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1965)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 235, 348)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 728)
[M::mem_pestat] mean and std.dev: (264.48, 135.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 918)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (450, 1292, 2190)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5670)
[M::mem_pestat] mean and std.dev: (1244.64, 1061.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7410)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 322, 663)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1573)
[M::mem_pestat] mean and std.dev: (423.28, 318.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2028)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697810 sequences (100000105 bp) in 2.715 CPU sec, 2.889 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 290817, 33, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 255, 485)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1153)
[M::mem_pestat] mean and std.dev: (331.93, 255.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1487)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 240, 353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 737)
[M::mem_pestat] mean and std.dev: (268.16, 136.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 929)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (122, 367, 672)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1772)
[M::mem_pestat] mean and std.dev: (346.97, 286.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2322)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 340, 560)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1256)
[M::mem_pestat] mean and std.dev: (341.70, 196.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1604)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700230 reads in 212.495 CPU sec, 6.761 real sec
[M::process] read 696900 sequences (100000128 bp) in 1.910 CPU sec, 1.918 real sec...
sorting block 56, #reads = 1087442 mem = 536878289 peak = 1044783104
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 290967, 25, 80)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 243, 349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 689)
[M::mem_pestat] mean and std.dev: (252.26, 119.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 859)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 242, 355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 741)
[M::mem_pestat] mean and std.dev: (269.64, 136.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 934)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 801, 1707)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4703)
[M::mem_pestat] mean and std.dev: (1077.72, 1085.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6201)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 337, 497)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1083)
[M::mem_pestat] mean and std.dev: (321.35, 194.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1376)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696008 sequences (100000046 bp) in 1.966 CPU sec, 1.978 real sec...
[M::mem_process_seqs] Processed 697810 reads in 102.679 CPU sec, 3.302 real sec
sorting block 57, #reads = 1086490 mem = 536877797 peak = 1044783104
[M::mem_process_seqs] Processed 698726 reads in 267.045 CPU sec, 8.530 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 290373, 33, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 316, 478)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1098)
[M::mem_pestat] mean and std.dev: (305.21, 190.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1408)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 245, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 744)
[M::mem_pestat] mean and std.dev: (272.12, 137.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 937)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (277, 508, 1115)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2791)
[M::mem_pestat] mean and std.dev: (719.72, 547.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3629)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 314, 584)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1358)
[M::mem_pestat] mean and std.dev: (349.70, 225.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1745)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696038 sequences (100000071 bp) in 2.538 CPU sec, 2.724 real sec...
[M::process] read 55032 sequences (7870959 bp) in 0.371 CPU sec, 0.371 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (88, 290524, 33, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 324, 1217)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3253)
[M::mem_pestat] mean and std.dev: (593.93, 614.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4271)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 247, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 748)
[M::mem_pestat] mean and std.dev: (273.73, 137.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 942)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (137, 412, 1241)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3449)
[M::mem_pestat] mean and std.dev: (481.75, 595.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4553)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 316, 471)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1019)
[M::mem_pestat] mean and std.dev: (291.64, 155.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1293)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696900 reads in 180.948 CPU sec, 5.777 real sec
sorting block 58, #reads = 1085001 mem = 536880425 peak = 1044783104
[M::mem_process_seqs] Processed 696008 reads in 102.513 CPU sec, 3.274 real sec
sorting block 59, #reads = 1086233 mem = 536879781 peak = 1044783104
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 290726, 21, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 306, 513)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1175)
[M::mem_pestat] mean and std.dev: (319.15, 226.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1506)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 249, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 760)
[M::mem_pestat] mean and std.dev: (276.18, 139.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 958)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (379, 981, 3184)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8794)
[M::mem_pestat] mean and std.dev: (1248.95, 1446.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11599)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 296, 555)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1249)
[M::mem_pestat] mean and std.dev: (352.76, 237.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1596)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (7, 22947, 0, 5)
[M::mem_pestat] skip orientation FF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 240, 347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 721)
[M::mem_pestat] mean and std.dev: (264.64, 132.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 908)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] skip orientation RR as there are not enough pairs
[M::mem_process_seqs] Processed 696038 reads in 94.469 CPU sec, 3.070 real sec
[M::mem_process_seqs] Processed 55032 reads in 23.847 CPU sec, 0.784 real sec
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000a06d1
  features: 1f8bfbff fffab20b
  extended: f1bf27eb 1b407f7e
  amd bits: 2c100800 00000121
     brand: Intel(R) Xeon(R) 6975P-C
threads: 31
algo: bwa-mem
license: sentieon:klib=31
reads: 65692766
overall: 69860057088 mem 11303.132 user 549.732 sys 430.767 real
[main] Version: 0.7.17-r1188
[main] CMD: /opt/conda/share/sentieon-202308.03-3/libexec/bwa mem -K 100000000 -Y -R @RG\tID:A23MHWWLT4.1136_27F-T1-TDNA-1_A23MHWWLT4_1.L002\tPU:L002\tSM:1136_27F-T1-TDNA-1_A23MHWWLT4_1\tLB:1136_27F-T1-TDNA-1_A23MHWWLT4_1\tDS:s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta\tPL:ILLUMINA -t 31 ./BWAIndex/Homo_sapiens_assembly38.fasta.64 0001.1136_27F-T1-TDNA-1_A23MHWWLT4_1_R1.fastq.gz 0001.1136_27F-T1-TDNA-1_A23MHWWLT4_1_R2.fastq.gz
[main] Real time: 430.804 sec; CPU: 11852.867 sec
sorting block 60, #reads = 968388 mem = 479239296 peak = 1044783104
uniq header count 1
merging 61 blocks
sw version: sentieon-genomics-202308.03
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000a06d1
  features: 1f8bfbff fffab20b
  extended: f1bf27eb 1b407f7e
  amd bits: 2c100800 00000121
     brand: Intel(R) Xeon(R) 6975P-C
threads: 31 max 192
algo: util-sort
license: sentieon:util=1
output file size: 3663193864
output reads: 66249384
bam_mem_sort: 61 calls 42.538 user 1.102 sys 44.768 real
bam_write: 61 calls 37.518 user 3.046 sys 72.585 real
execute: 1 calls 16.339 user 0.878 sys 451.243 real
merge_files: 1 calls 16.311 user 0.842 sys 19.804 real
parse_chunk: 975 calls 45.043 user 12.259 sys 70.390 real
read_chunk: 2634 calls 22.735 user 17.390 sys 334.311 real
sort_block: 1 calls 16.998 user 16.775 sys 325.579 real
write_chunk: 1657 calls 15.916 user 0.683 sys 19.056 real
overall: 2790223872 mem 805.616 user 50.583 sys 451.264 real
ls: cannot access '*.cram': No such file or directory