This software is licensed to bgold@natera.com by Sentieon Inc.
cmdline: /opt/conda/share/sentieon-202308.03-3/libexec/util sort -r Homo_sapiens_assembly38.fasta -t 31 -o 659_dm4-T1-TDNA-1_A23MHWWLT4_1.bam --sam2bam -
This software is licensed to bgold@natera.com by Sentieon Inc.
version: sentieon-genomics-202308.03
[M::bwa_idx_load_from_disk] read 3171 ALT contigs
[M::main_mem] bwa index loaded in 1919.712 CPU sec, 74.945 real sec
[M::process] read 755484 sequences (100000024 bp) in 1.216 CPU sec, 1.225 real sec...
[M::process] read 753938 sequences (100000009 bp) in 1.920 CPU sec, 1.919 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 304067, 13, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 241, 375)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 813)
[M::mem_pestat] mean and std.dev: (220.10, 100.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1032)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (115, 156, 213)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 409)
[M::mem_pestat] mean and std.dev: (169.40, 71.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 507)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 285, 1597)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4457)
[M::mem_pestat] mean and std.dev: (928.85, 1145.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5887)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 271, 792)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2024)
[M::mem_pestat] mean and std.dev: (324.57, 271.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2640)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 753050 sequences (100000258 bp) in 1.818 CPU sec, 1.812 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (19, 303631, 27, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (126, 266, 570)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1458)
[M::mem_pestat] mean and std.dev: (249.88, 177.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1902)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (116, 157, 215)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 413)
[M::mem_pestat] mean and std.dev: (170.68, 72.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 512)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (109, 483, 1669)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4789)
[M::mem_pestat] mean and std.dev: (815.65, 820.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6349)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 290, 665)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1653)
[M::mem_pestat] mean and std.dev: (398.29, 330.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2147)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 752074 sequences (100000024 bp) in 2.079 CPU sec, 2.088 real sec...
[M::mem_process_seqs] Processed 755484 reads in 206.570 CPU sec, 6.490 real sec
[M::mem_process_seqs] Processed 753938 reads in 143.321 CPU sec, 4.567 real sec
sorting block 0, #reads = 1118201 mem = 536878204 peak = 588173312
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 303025, 25, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (143, 189, 2107)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6035)
[M::mem_pestat] mean and std.dev: (599.19, 812.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7999)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (116, 158, 216)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 416)
[M::mem_pestat] mean and std.dev: (171.38, 72.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 516)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (305, 567, 2200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5990)
[M::mem_pestat] mean and std.dev: (1250.60, 1467.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7885)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 472, 1267)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3353)
[M::mem_pestat] mean and std.dev: (661.97, 588.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4396)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 752206 sequences (100000223 bp) in 2.665 CPU sec, 2.734 real sec...
[M::process] read 751540 sequences (100000136 bp) in 2.479 CPU sec, 2.481 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 303087, 31, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (146, 217, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 797)
[M::mem_pestat] mean and std.dev: (224.54, 126.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1014)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 158, 216)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 414)
[M::mem_pestat] mean and std.dev: (171.75, 72.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 513)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 779, 1738)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4780)
[M::mem_pestat] mean and std.dev: (989.68, 904.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6301)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (232, 325, 753)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1795)
[M::mem_pestat] mean and std.dev: (397.77, 291.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2316)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 753050 reads in 201.333 CPU sec, 6.407 real sec
[M::mem_process_seqs] Processed 752074 reads in 139.368 CPU sec, 4.450 real sec
sorting block 1, #reads = 1118449 mem = 536880831 peak = 745459712
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 303115, 29, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 357, 1924)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5432)
[M::mem_pestat] mean and std.dev: (805.83, 787.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7186)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (116, 159, 217)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 419)
[M::mem_pestat] mean and std.dev: (172.43, 73.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 520)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (59, 223, 1787)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5243)
[M::mem_pestat] mean and std.dev: (852.03, 1021.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6971)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 341, 900)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2390)
[M::mem_pestat] mean and std.dev: (464.25, 401.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3135)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 751102 sequences (100000116 bp) in 3.225 CPU sec, 3.483 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 302726, 31, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (242, 541, 667)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1517)
[M::mem_pestat] mean and std.dev: (464.34, 294.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1942)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 159, 218)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 420)
[M::mem_pestat] mean and std.dev: (173.18, 74.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 521)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (353, 395, 2092)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5570)
[M::mem_pestat] mean and std.dev: (952.37, 994.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7309)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 471, 1630)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4450)
[M::mem_pestat] mean and std.dev: (997.63, 1052.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5860)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 752206 reads in 202.044 CPU sec, 6.481 real sec
[M::process] read 751534 sequences (100000239 bp) in 2.501 CPU sec, 2.526 real sec...
sorting block 2, #reads = 1117145 mem = 536880326 peak = 772661248
[M::mem_process_seqs] Processed 751540 reads in 148.669 CPU sec, 4.735 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 302096, 21, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 358, 479)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1035)
[M::mem_pestat] mean and std.dev: (294.56, 134.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1313)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 160, 218)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 420)
[M::mem_pestat] mean and std.dev: (173.07, 73.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 521)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (121, 246, 679)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1795)
[M::mem_pestat] mean and std.dev: (382.67, 356.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2353)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 278, 1386)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3888)
[M::mem_pestat] mean and std.dev: (444.86, 514.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5139)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 3, #reads = 1117227 mem = 536883829 peak = 809607168
[M::process] read 751942 sequences (100000280 bp) in 3.181 CPU sec, 3.359 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 303033, 22, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (145, 242, 755)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1975)
[M::mem_pestat] mean and std.dev: (474.08, 407.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2585)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 159, 218)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 420)
[M::mem_pestat] mean and std.dev: (172.75, 73.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 521)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (125, 728, 1588)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4514)
[M::mem_pestat] mean and std.dev: (804.67, 866.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5977)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 374, 1362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3758)
[M::mem_pestat] mean and std.dev: (804.35, 838.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4956)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 751172 sequences (100000268 bp) in 2.282 CPU sec, 2.312 real sec...
[M::mem_process_seqs] Processed 751102 reads in 203.356 CPU sec, 6.637 real sec
[M::mem_process_seqs] Processed 751534 reads in 141.770 CPU sec, 4.631 real sec
sorting block 4, #reads = 1116613 mem = 536882612 peak = 809607168
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 302749, 28, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 550, 1375)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3805)
[M::mem_pestat] mean and std.dev: (753.44, 885.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5020)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 159, 216)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 414)
[M::mem_pestat] mean and std.dev: (171.77, 72.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 513)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (120, 257, 1405)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3975)
[M::mem_pestat] mean and std.dev: (653.21, 752.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5260)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 486, 1634)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4486)
[M::mem_pestat] mean and std.dev: (840.62, 789.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5912)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 750822 sequences (100000056 bp) in 2.727 CPU sec, 3.043 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 302377, 21, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 455, 1355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3639)
[M::mem_pestat] mean and std.dev: (859.16, 801.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4781)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 159, 218)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 420)
[M::mem_pestat] mean and std.dev: (172.85, 73.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 521)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (140, 232, 1192)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3296)
[M::mem_pestat] mean and std.dev: (533.62, 547.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4348)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 608, 1041)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2747)
[M::mem_pestat] mean and std.dev: (603.71, 518.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3600)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 749842 sequences (100000142 bp) in 2.210 CPU sec, 2.224 real sec...
[M::mem_process_seqs] Processed 751942 reads in 205.991 CPU sec, 6.850 real sec
[M::mem_process_seqs] Processed 751172 reads in 139.866 CPU sec, 4.639 real sec
sorting block 5, #reads = 1115220 mem = 536877426 peak = 809607168
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 302582, 37, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 272, 1251)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3417)
[M::mem_pestat] mean and std.dev: (582.50, 568.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4500)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 160, 218)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 420)
[M::mem_pestat] mean and std.dev: (173.04, 73.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 521)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (99, 431, 1156)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3270)
[M::mem_pestat] mean and std.dev: (593.64, 592.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4327)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (143, 250, 504)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1226)
[M::mem_pestat] mean and std.dev: (249.07, 136.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1587)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 748936 sequences (100000281 bp) in 2.906 CPU sec, 3.212 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 302371, 25, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 291, 728)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1874)
[M::mem_pestat] mean and std.dev: (360.03, 294.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2447)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 160, 219)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 421)
[M::mem_pestat] mean and std.dev: (173.45, 73.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 522)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 420, 1121)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3069)
[M::mem_pestat] mean and std.dev: (701.33, 659.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4043)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 323, 1680)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4732)
[M::mem_pestat] mean and std.dev: (1103.91, 1384.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6643)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 748156 sequences (100000135 bp) in 2.482 CPU sec, 2.491 real sec...
[M::mem_process_seqs] Processed 750822 reads in 208.511 CPU sec, 6.908 real sec
sorting block 6, #reads = 1118042 mem = 536884144 peak = 812371968
[M::mem_process_seqs] Processed 749842 reads in 141.466 CPU sec, 4.717 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 302128, 20, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 467, 1517)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4205)
[M::mem_pestat] mean and std.dev: (717.08, 739.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5549)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 161, 220)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 424)
[M::mem_pestat] mean and std.dev: (174.27, 74.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 526)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (493, 1105, 1170)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2524)
[M::mem_pestat] mean and std.dev: (841.26, 476.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3201)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 301, 696)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1720)
[M::mem_pestat] mean and std.dev: (367.97, 281.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2232)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 7, #reads = 1115959 mem = 536878327 peak = 910876672
[M::process] read 748192 sequences (100000116 bp) in 2.842 CPU sec, 3.093 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 301524, 30, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 417, 1060)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2836)
[M::mem_pestat] mean and std.dev: (590.72, 573.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3724)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (119, 161, 220)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 422)
[M::mem_pestat] mean and std.dev: (174.72, 73.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 523)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 454, 1294)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3448)
[M::mem_pestat] mean and std.dev: (686.14, 593.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4525)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 256, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 652)
[M::mem_pestat] mean and std.dev: (247.47, 114.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 814)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 748936 reads in 205.425 CPU sec, 6.768 real sec
[M::process] read 749490 sequences (100000090 bp) in 2.600 CPU sec, 2.657 real sec...
[M::mem_process_seqs] Processed 748156 reads in 143.054 CPU sec, 4.844 real sec
sorting block 8, #reads = 1116664 mem = 536879143 peak = 910876672
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 301333, 30, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 377, 1222)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3316)
[M::mem_pestat] mean and std.dev: (636.85, 655.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4363)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 161, 219)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 421)
[M::mem_pestat] mean and std.dev: (174.29, 73.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 522)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (428, 520, 1885)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4799)
[M::mem_pestat] mean and std.dev: (984.96, 1129.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6256)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 244, 848)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2192)
[M::mem_pestat] mean and std.dev: (476.19, 445.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2864)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 747358 sequences (100000050 bp) in 3.169 CPU sec, 3.427 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 301619, 30, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (439, 926, 1764)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4414)
[M::mem_pestat] mean and std.dev: (944.34, 706.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5739)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 160, 218)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 418)
[M::mem_pestat] mean and std.dev: (173.47, 73.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 518)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (132, 636, 1406)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3954)
[M::mem_pestat] mean and std.dev: (840.07, 901.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5228)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 281, 1180)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3144)
[M::mem_pestat] mean and std.dev: (646.52, 701.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4126)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 747280 sequences (100000060 bp) in 2.250 CPU sec, 2.271 real sec...
[M::mem_process_seqs] Processed 748192 reads in 220.183 CPU sec, 7.391 real sec
[M::mem_process_seqs] Processed 749490 reads in 153.317 CPU sec, 5.103 real sec
sorting block 9, #reads = 1113703 mem = 536887993 peak = 910876672
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 301154, 13, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 326, 452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1024)
[M::mem_pestat] mean and std.dev: (293.09, 173.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1310)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (119, 161, 220)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 422)
[M::mem_pestat] mean and std.dev: (174.52, 73.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 523)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 420, 3883)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 11293)
[M::mem_pestat] mean and std.dev: (1656.00, 2062.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14998)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 279, 839)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2261)
[M::mem_pestat] mean and std.dev: (461.53, 479.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2972)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 746748 sequences (100000041 bp) in 2.762 CPU sec, 3.060 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 300555, 31, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 226, 506)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1202)
[M::mem_pestat] mean and std.dev: (262.79, 175.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1550)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (119, 162, 220)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 422)
[M::mem_pestat] mean and std.dev: (174.78, 73.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 523)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (135, 606, 1418)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3984)
[M::mem_pestat] mean and std.dev: (743.14, 704.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5267)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 401, 1027)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2705)
[M::mem_pestat] mean and std.dev: (514.00, 398.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3544)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 746284 sequences (100000157 bp) in 2.286 CPU sec, 2.295 real sec...
[M::mem_process_seqs] Processed 747358 reads in 212.506 CPU sec, 7.145 real sec
sorting block 10, #reads = 1109247 mem = 536880493 peak = 910876672
[M::mem_process_seqs] Processed 747280 reads in 144.518 CPU sec, 4.774 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 300969, 26, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (138, 272, 893)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2403)
[M::mem_pestat] mean and std.dev: (518.88, 550.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3158)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (119, 162, 220)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 422)
[M::mem_pestat] mean and std.dev: (174.85, 73.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 523)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (56, 312, 1562)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4574)
[M::mem_pestat] mean and std.dev: (868.12, 1110.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6080)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 256, 491)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1131)
[M::mem_pestat] mean and std.dev: (291.44, 168.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1451)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 11, #reads = 1112759 mem = 536878967 peak = 922275840
[M::process] read 745402 sequences (100000183 bp) in 3.229 CPU sec, 3.493 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 300294, 27, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (256, 353, 2577)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7219)
[M::mem_pestat] mean and std.dev: (1300.61, 1903.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9540)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (119, 162, 221)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 425)
[M::mem_pestat] mean and std.dev: (175.81, 74.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 527)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (78, 467, 983)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2793)
[M::mem_pestat] mean and std.dev: (453.12, 412.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3698)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 235, 828)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2118)
[M::mem_pestat] mean and std.dev: (442.62, 413.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2763)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 746748 reads in 208.964 CPU sec, 6.931 real sec
[M::process] read 745506 sequences (100000090 bp) in 2.489 CPU sec, 2.637 real sec...
[M::mem_process_seqs] Processed 746284 reads in 146.741 CPU sec, 4.991 real sec
sorting block 12, #reads = 1114258 mem = 536879511 peak = 922275840
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 299743, 27, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 329, 1159)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3147)
[M::mem_pestat] mean and std.dev: (608.09, 648.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4141)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (120, 163, 222)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 426)
[M::mem_pestat] mean and std.dev: (176.28, 74.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 528)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 481, 1547)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4209)
[M::mem_pestat] mean and std.dev: (681.96, 854.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5540)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 345, 609)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1479)
[M::mem_pestat] mean and std.dev: (362.86, 278.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1914)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 745302 sequences (100000034 bp) in 2.866 CPU sec, 3.315 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 300693, 29, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (145, 237, 513)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1249)
[M::mem_pestat] mean and std.dev: (281.20, 211.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1617)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (119, 163, 222)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 428)
[M::mem_pestat] mean and std.dev: (176.28, 74.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 531)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (140, 226, 639)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1637)
[M::mem_pestat] mean and std.dev: (330.00, 346.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2136)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 414, 1737)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4825)
[M::mem_pestat] mean and std.dev: (1165.34, 1295.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6369)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 751822 sequences (100000034 bp) in 2.263 CPU sec, 2.271 real sec...
[M::mem_process_seqs] Processed 745402 reads in 213.431 CPU sec, 7.278 real sec
[M::mem_process_seqs] Processed 745506 reads in 144.200 CPU sec, 4.791 real sec
sorting block 13, #reads = 1111284 mem = 536878325 peak = 922275840
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 300300, 19, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 258, 851)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2231)
[M::mem_pestat] mean and std.dev: (428.59, 353.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2921)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (119, 163, 222)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 428)
[M::mem_pestat] mean and std.dev: (176.37, 74.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 531)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 471, 1521)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4261)
[M::mem_pestat] mean and std.dev: (793.79, 761.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5631)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 277, 921)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2397)
[M::mem_pestat] mean and std.dev: (473.80, 515.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3135)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 753030 sequences (100000019 bp) in 3.066 CPU sec, 3.301 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 302629, 20, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 287, 956)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2558)
[M::mem_pestat] mean and std.dev: (531.06, 492.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3359)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 159, 216)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 414)
[M::mem_pestat] mean and std.dev: (172.02, 72.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 513)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 893, 1430)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3914)
[M::mem_pestat] mean and std.dev: (774.79, 596.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5156)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (259, 731, 1163)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2971)
[M::mem_pestat] mean and std.dev: (769.62, 685.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3875)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 745302 reads in 211.246 CPU sec, 7.022 real sec
[M::process] read 752578 sequences (100000124 bp) in 2.544 CPU sec, 2.572 real sec...
sorting block 14, #reads = 1111354 mem = 536879170 peak = 922275840
[M::mem_process_seqs] Processed 751822 reads in 146.276 CPU sec, 4.755 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 303213, 22, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 410, 962)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2590)
[M::mem_pestat] mean and std.dev: (650.72, 647.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3404)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (116, 158, 216)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 416)
[M::mem_pestat] mean and std.dev: (171.54, 72.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 516)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (89, 422, 780)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2162)
[M::mem_pestat] mean and std.dev: (385.50, 407.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2853)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 286, 731)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1739)
[M::mem_pestat] mean and std.dev: (464.55, 373.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2243)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 15, #reads = 1112805 mem = 536883792 peak = 931741696
[M::process] read 752208 sequences (100000226 bp) in 3.024 CPU sec, 3.362 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 302984, 20, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 240, 507)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1223)
[M::mem_pestat] mean and std.dev: (297.22, 221.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1581)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (116, 158, 216)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 416)
[M::mem_pestat] mean and std.dev: (171.60, 72.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 516)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 508, 1412)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3824)
[M::mem_pestat] mean and std.dev: (490.12, 575.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5030)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 258, 394)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 874)
[M::mem_pestat] mean and std.dev: (252.90, 146.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1114)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 753030 reads in 208.797 CPU sec, 6.865 real sec
[M::process] read 751906 sequences (100000085 bp) in 2.510 CPU sec, 2.520 real sec...
[M::mem_process_seqs] Processed 752578 reads in 144.693 CPU sec, 4.991 real sec
sorting block 16, #reads = 1117971 mem = 536880426 peak = 931741696
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 303672, 18, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 456, 1207)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3285)
[M::mem_pestat] mean and std.dev: (539.83, 487.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4324)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 158, 217)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 417)
[M::mem_pestat] mean and std.dev: (172.14, 73.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 517)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (85, 898, 1701)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4933)
[M::mem_pestat] mean and std.dev: (1052.47, 1217.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6549)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 306, 787)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1931)
[M::mem_pestat] mean and std.dev: (436.91, 365.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2503)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 750776 sequences (100000196 bp) in 2.985 CPU sec, 3.353 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 303274, 18, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 380, 1603)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4471)
[M::mem_pestat] mean and std.dev: (504.45, 586.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5905)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 159, 216)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 414)
[M::mem_pestat] mean and std.dev: (171.92, 72.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 513)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (395, 694, 1555)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3875)
[M::mem_pestat] mean and std.dev: (843.44, 801.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5035)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 325, 1080)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2950)
[M::mem_pestat] mean and std.dev: (516.09, 574.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3885)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 750350 sequences (100000031 bp) in 2.464 CPU sec, 2.469 real sec...
[M::mem_process_seqs] Processed 752208 reads in 209.398 CPU sec, 7.199 real sec
[M::mem_process_seqs] Processed 751906 reads in 142.593 CPU sec, 4.784 real sec
sorting block 17, #reads = 1118337 mem = 536879944 peak = 931741696
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 302524, 22, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (143, 255, 908)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2438)
[M::mem_pestat] mean and std.dev: (430.69, 493.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3203)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 159, 218)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 420)
[M::mem_pestat] mean and std.dev: (172.93, 73.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 521)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 571, 1786)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4960)
[M::mem_pestat] mean and std.dev: (668.32, 642.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6547)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 332, 905)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2353)
[M::mem_pestat] mean and std.dev: (379.28, 337.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3077)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 750208 sequences (100000279 bp) in 3.359 CPU sec, 3.681 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 302454, 9, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 255, 748)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1908)
[M::mem_pestat] mean and std.dev: (521.41, 582.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2850)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 160, 219)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 423)
[M::mem_pestat] mean and std.dev: (173.90, 74.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 525)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 298, 694)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1736)
[M::mem_pestat] mean and std.dev: (395.67, 290.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2257)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 750776 reads in 207.044 CPU sec, 7.147 real sec
sorting block 18, #reads = 1119474 mem = 536881250 peak = 931741696
[M::process] read 751630 sequences (100000123 bp) in 2.602 CPU sec, 2.783 real sec...
[M::mem_process_seqs] Processed 750350 reads in 147.874 CPU sec, 4.877 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 302715, 21, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (138, 251, 514)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1266)
[M::mem_pestat] mean and std.dev: (260.61, 176.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1642)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 160, 220)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 426)
[M::mem_pestat] mean and std.dev: (174.05, 74.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 529)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 573, 2380)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6678)
[M::mem_pestat] mean and std.dev: (1178.57, 1326.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8827)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 290, 1411)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3863)
[M::mem_pestat] mean and std.dev: (719.41, 724.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5089)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 19, #reads = 1118818 mem = 536878346 peak = 931741696
[M::process] read 750686 sequences (100000041 bp) in 3.191 CPU sec, 3.445 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 303273, 36, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 298, 551)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1281)
[M::mem_pestat] mean and std.dev: (320.76, 255.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1646)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 159, 217)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 417)
[M::mem_pestat] mean and std.dev: (172.16, 72.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 517)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (54, 204, 1163)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3381)
[M::mem_pestat] mean and std.dev: (639.03, 701.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4490)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 441, 1263)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3411)
[M::mem_pestat] mean and std.dev: (585.07, 499.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4485)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 750208 reads in 211.709 CPU sec, 7.155 real sec
[M::mem_process_seqs] Processed 751630 reads in 145.973 CPU sec, 4.867 real sec
[M::process] read 750008 sequences (100000042 bp) in 2.731 CPU sec, 2.886 real sec...
sorting block 20, #reads = 1115915 mem = 536881689 peak = 931741696
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 302874, 20, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 243, 541)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1295)
[M::mem_pestat] mean and std.dev: (324.16, 240.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1672)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 159, 218)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 420)
[M::mem_pestat] mean and std.dev: (172.70, 73.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 521)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 508, 717)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1731)
[M::mem_pestat] mean and std.dev: (469.20, 296.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2238)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 223, 629)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1571)
[M::mem_pestat] mean and std.dev: (336.46, 318.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2042)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 749110 sequences (100000046 bp) in 3.127 CPU sec, 3.455 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 302453, 31, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (298, 552, 1178)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2938)
[M::mem_pestat] mean and std.dev: (778.86, 675.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3818)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 160, 218)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 420)
[M::mem_pestat] mean and std.dev: (173.34, 73.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 521)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (128, 353, 1521)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4307)
[M::mem_pestat] mean and std.dev: (592.67, 653.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5700)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 244, 933)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2473)
[M::mem_pestat] mean and std.dev: (510.56, 565.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3243)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 750686 reads in 200.590 CPU sec, 6.565 real sec
[M::mem_process_seqs] Processed 750008 reads in 140.297 CPU sec, 4.540 real sec
[M::process] read 748508 sequences (100000131 bp) in 2.546 CPU sec, 2.631 real sec...
sorting block 21, #reads = 1117449 mem = 536878935 peak = 931741696
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 302519, 19, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 295, 899)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2341)
[M::mem_pestat] mean and std.dev: (543.84, 559.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3062)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 161, 219)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 421)
[M::mem_pestat] mean and std.dev: (173.81, 73.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 522)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (232, 621, 3465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9931)
[M::mem_pestat] mean and std.dev: (1818.37, 2470.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13164)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 244, 422)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 932)
[M::mem_pestat] mean and std.dev: (259.44, 119.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1187)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 748356 sequences (100000038 bp) in 3.220 CPU sec, 3.749 real sec...
sorting block 22, #reads = 1117029 mem = 536880222 peak = 980791296
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 301703, 22, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (142, 180, 849)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2263)
[M::mem_pestat] mean and std.dev: (280.67, 274.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2970)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 161, 219)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 421)
[M::mem_pestat] mean and std.dev: (174.05, 73.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 522)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (340, 632, 983)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2269)
[M::mem_pestat] mean and std.dev: (642.19, 506.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2912)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 278, 1408)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3802)
[M::mem_pestat] mean and std.dev: (636.16, 615.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4999)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 749110 reads in 200.406 CPU sec, 6.541 real sec
[M::mem_process_seqs] Processed 748508 reads in 141.054 CPU sec, 4.580 real sec
[M::process] read 748578 sequences (100000044 bp) in 2.458 CPU sec, 2.580 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 301633, 24, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 320, 798)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2038)
[M::mem_pestat] mean and std.dev: (411.25, 317.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2658)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 160, 218)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 418)
[M::mem_pestat] mean and std.dev: (173.56, 72.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 518)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 712, 1082)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2908)
[M::mem_pestat] mean and std.dev: (673.45, 639.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3821)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 225, 499)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1189)
[M::mem_pestat] mean and std.dev: (287.67, 238.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1534)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 23, #reads = 1116339 mem = 536878075 peak = 980791296
[M::process] read 750894 sequences (100000004 bp) in 3.106 CPU sec, 3.436 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 301576, 18, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 296, 1509)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4209)
[M::mem_pestat] mean and std.dev: (599.90, 878.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5559)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 160, 218)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 418)
[M::mem_pestat] mean and std.dev: (173.19, 72.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 518)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (312, 880, 1403)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3585)
[M::mem_pestat] mean and std.dev: (854.56, 669.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4676)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 226, 462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1084)
[M::mem_pestat] mean and std.dev: (257.36, 178.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1395)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 748356 reads in 204.713 CPU sec, 6.704 real sec
[M::process] read 747744 sequences (100000218 bp) in 2.476 CPU sec, 2.623 real sec...
[M::mem_process_seqs] Processed 748578 reads in 143.024 CPU sec, 4.841 real sec
sorting block 24, #reads = 1114645 mem = 536887315 peak = 980791296
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 302015, 20, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 381, 562)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1338)
[M::mem_pestat] mean and std.dev: (338.07, 245.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1726)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 159, 216)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 414)
[M::mem_pestat] mean and std.dev: (171.93, 71.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 513)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 371, 1060)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2790)
[M::mem_pestat] mean and std.dev: (472.65, 444.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3655)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 230, 468)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1022)
[M::mem_pestat] mean and std.dev: (328.64, 256.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1356)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 747770 sequences (100000250 bp) in 3.283 CPU sec, 3.634 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 300859, 28, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 295, 767)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1973)
[M::mem_pestat] mean and std.dev: (421.79, 413.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2576)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 161, 219)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 421)
[M::mem_pestat] mean and std.dev: (174.05, 73.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 522)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (451, 1271, 4013)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 11137)
[M::mem_pestat] mean and std.dev: (1810.71, 1813.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14699)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 360, 660)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1546)
[M::mem_pestat] mean and std.dev: (351.00, 257.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1989)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 750894 reads in 217.150 CPU sec, 7.289 real sec
[M::process] read 747204 sequences (100000300 bp) in 2.680 CPU sec, 2.865 real sec...
[M::mem_process_seqs] Processed 747744 reads in 153.819 CPU sec, 5.014 real sec
sorting block 25, #reads = 1112835 mem = 536878860 peak = 980791296
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 301312, 26, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (145, 263, 495)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1195)
[M::mem_pestat] mean and std.dev: (327.22, 310.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1569)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 161, 219)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 421)
[M::mem_pestat] mean and std.dev: (173.95, 72.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 522)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (670, 1366, 3281)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8503)
[M::mem_pestat] mean and std.dev: (2063.46, 1715.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11114)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 200, 821)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2139)
[M::mem_pestat] mean and std.dev: (542.24, 559.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2798)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 26, #reads = 1111337 mem = 536875228 peak = 983142400
[M::process] read 746714 sequences (100000082 bp) in 3.054 CPU sec, 3.568 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 301343, 25, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 430, 781)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2041)
[M::mem_pestat] mean and std.dev: (493.14, 448.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2671)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (119, 162, 220)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 422)
[M::mem_pestat] mean and std.dev: (174.84, 73.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 523)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (140, 464, 1893)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5399)
[M::mem_pestat] mean and std.dev: (958.16, 1111.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7152)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 221, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 737)
[M::mem_pestat] mean and std.dev: (201.83, 70.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 934)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 747770 reads in 207.350 CPU sec, 6.798 real sec
[M::mem_process_seqs] Processed 747204 reads in 145.398 CPU sec, 4.737 real sec
[M::process] read 746520 sequences (100000161 bp) in 2.617 CPU sec, 2.739 real sec...
sorting block 27, #reads = 1112896 mem = 536878011 peak = 983142400
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 300978, 23, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 261, 1808)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5130)
[M::mem_pestat] mean and std.dev: (929.85, 1391.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6791)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (119, 162, 221)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 425)
[M::mem_pestat] mean and std.dev: (175.48, 74.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 527)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (294, 332, 1084)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2664)
[M::mem_pestat] mean and std.dev: (454.00, 338.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3454)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (144, 243, 597)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1503)
[M::mem_pestat] mean and std.dev: (376.56, 371.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1956)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 746202 sequences (100000249 bp) in 2.836 CPU sec, 3.762 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 300887, 28, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 312, 919)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2395)
[M::mem_pestat] mean and std.dev: (516.56, 504.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3133)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (119, 162, 221)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 425)
[M::mem_pestat] mean and std.dev: (175.37, 73.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 527)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (60, 277, 1740)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5100)
[M::mem_pestat] mean and std.dev: (750.86, 897.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6780)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 216, 305)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 603)
[M::mem_pestat] mean and std.dev: (214.69, 73.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 752)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 746714 reads in 204.922 CPU sec, 6.711 real sec
[M::mem_process_seqs] Processed 746520 reads in 143.505 CPU sec, 4.651 real sec
[M::process] read 746598 sequences (100000263 bp) in 2.528 CPU sec, 2.623 real sec...
sorting block 28, #reads = 1112900 mem = 536881101 peak = 983142400
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 300406, 23, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 335, 954)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2552)
[M::mem_pestat] mean and std.dev: (543.12, 502.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3351)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (119, 162, 221)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 425)
[M::mem_pestat] mean and std.dev: (175.69, 74.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 527)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 204, 844)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2212)
[M::mem_pestat] mean and std.dev: (455.86, 485.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2896)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 354, 1075)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2737)
[M::mem_pestat] mean and std.dev: (558.31, 521.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3568)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 753174 sequences (100000028 bp) in 2.968 CPU sec, 3.414 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 301248, 24, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 279, 1036)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2786)
[M::mem_pestat] mean and std.dev: (568.29, 571.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3661)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (119, 162, 222)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 428)
[M::mem_pestat] mean and std.dev: (176.13, 74.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 531)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 533, 1134)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3088)
[M::mem_pestat] mean and std.dev: (546.90, 612.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4065)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 316, 624)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1484)
[M::mem_pestat] mean and std.dev: (376.07, 281.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1914)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 746202 reads in 210.709 CPU sec, 6.866 real sec
[M::process] read 753392 sequences (100000214 bp) in 2.616 CPU sec, 2.668 real sec...
sorting block 29, #reads = 1113114 mem = 536887005 peak = 983142400
[M::mem_process_seqs] Processed 746598 reads in 147.126 CPU sec, 4.887 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 303299, 31, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 248, 1230)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3346)
[M::mem_pestat] mean and std.dev: (611.36, 756.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4404)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (116, 158, 215)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 413)
[M::mem_pestat] mean and std.dev: (171.20, 72.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 512)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (388, 528, 888)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1888)
[M::mem_pestat] mean and std.dev: (502.62, 259.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2388)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 374, 955)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2529)
[M::mem_pestat] mean and std.dev: (570.94, 617.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3316)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 30, #reads = 1112222 mem = 536880519 peak = 999378944
[M::process] read 752032 sequences (100000246 bp) in 2.852 CPU sec, 3.270 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 303178, 21, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (384, 997, 3636)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10140)
[M::mem_pestat] mean and std.dev: (2294.96, 2495.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13392)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (116, 158, 216)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 416)
[M::mem_pestat] mean and std.dev: (171.29, 72.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 516)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (330, 468, 794)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1722)
[M::mem_pestat] mean and std.dev: (431.00, 294.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2186)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 171, 865)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2327)
[M::mem_pestat] mean and std.dev: (442.04, 454.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3058)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 753174 reads in 205.798 CPU sec, 7.019 real sec
[M::process] read 751472 sequences (100000072 bp) in 2.546 CPU sec, 2.742 real sec...
[M::mem_process_seqs] Processed 753392 reads in 149.566 CPU sec, 4.945 real sec
sorting block 31, #reads = 1114260 mem = 536879321 peak = 999378944
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 302710, 27, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 264, 785)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2019)
[M::mem_pestat] mean and std.dev: (452.97, 449.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2636)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 159, 217)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 417)
[M::mem_pestat] mean and std.dev: (172.29, 73.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 517)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 468, 1403)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3857)
[M::mem_pestat] mean and std.dev: (654.48, 705.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5084)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 250, 614)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1486)
[M::mem_pestat] mean and std.dev: (355.78, 286.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1922)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 751174 sequences (100000269 bp) in 2.817 CPU sec, 3.213 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 303061, 21, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 394, 585)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1403)
[M::mem_pestat] mean and std.dev: (398.19, 284.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1812)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 159, 218)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 420)
[M::mem_pestat] mean and std.dev: (172.92, 73.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 521)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (106, 750, 1977)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5719)
[M::mem_pestat] mean and std.dev: (934.15, 1075.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7590)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (241, 496, 1847)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5059)
[M::mem_pestat] mean and std.dev: (1131.21, 1363.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6665)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 752032 reads in 201.578 CPU sec, 6.580 real sec
[M::process] read 749926 sequences (100000178 bp) in 2.432 CPU sec, 2.445 real sec...
[M::mem_process_seqs] Processed 751472 reads in 142.076 CPU sec, 4.811 real sec
sorting block 32, #reads = 1117037 mem = 536878147 peak = 999378944
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 302752, 19, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (138, 235, 776)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2052)
[M::mem_pestat] mean and std.dev: (492.71, 552.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2704)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 160, 218)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 420)
[M::mem_pestat] mean and std.dev: (173.23, 74.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 521)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 620, 1204)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3302)
[M::mem_pestat] mean and std.dev: (460.25, 400.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4351)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 333, 1479)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4113)
[M::mem_pestat] mean and std.dev: (904.54, 974.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5430)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 749804 sequences (100000273 bp) in 3.028 CPU sec, 3.782 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 302065, 20, 23)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 265, 650)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1650)
[M::mem_pestat] mean and std.dev: (319.02, 279.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2150)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 160, 219)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 421)
[M::mem_pestat] mean and std.dev: (173.83, 74.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 522)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 266, 844)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2134)
[M::mem_pestat] mean and std.dev: (436.26, 375.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2779)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 370, 1811)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5041)
[M::mem_pestat] mean and std.dev: (795.18, 931.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6656)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 751174 reads in 202.181 CPU sec, 6.801 real sec
sorting block 33, #reads = 1116478 mem = 536882624 peak = 1005473792
[M::process] read 749806 sequences (100000014 bp) in 2.478 CPU sec, 2.510 real sec...
[M::mem_process_seqs] Processed 749926 reads in 141.418 CPU sec, 4.708 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 302698, 12, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (228, 379, 948)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2388)
[M::mem_pestat] mean and std.dev: (541.95, 444.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3108)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 160, 219)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 421)
[M::mem_pestat] mean and std.dev: (173.73, 74.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 522)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 258, 903)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2415)
[M::mem_pestat] mean and std.dev: (415.45, 427.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3171)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (264, 347, 1265)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3267)
[M::mem_pestat] mean and std.dev: (483.74, 415.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4268)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 34, #reads = 1116218 mem = 536881213 peak = 1017323520
[M::process] read 750844 sequences (100000032 bp) in 2.887 CPU sec, 3.454 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 302206, 11, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 420, 808)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2056)
[M::mem_pestat] mean and std.dev: (469.00, 343.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2680)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 160, 219)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 421)
[M::mem_pestat] mean and std.dev: (173.93, 74.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 522)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 508, 2255)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6351)
[M::mem_pestat] mean and std.dev: (613.33, 667.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8399)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 307, 765)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1993)
[M::mem_pestat] mean and std.dev: (365.61, 361.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2607)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 749804 reads in 199.262 CPU sec, 6.701 real sec
[M::mem_process_seqs] Processed 749806 reads in 140.567 CPU sec, 4.517 real sec
[M::process] read 750176 sequences (100000200 bp) in 2.645 CPU sec, 2.712 real sec...
sorting block 35, #reads = 1115423 mem = 536883491 peak = 1017323520
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 303204, 21, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 437, 1190)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3176)
[M::mem_pestat] mean and std.dev: (793.42, 862.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4244)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 159, 217)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 417)
[M::mem_pestat] mean and std.dev: (172.37, 72.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 517)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (128, 518, 1635)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4649)
[M::mem_pestat] mean and std.dev: (781.81, 698.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6156)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 204, 966)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2590)
[M::mem_pestat] mean and std.dev: (533.69, 624.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3402)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 748742 sequences (100000290 bp) in 3.127 CPU sec, 3.763 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 302346, 22, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 339, 1106)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2974)
[M::mem_pestat] mean and std.dev: (768.77, 844.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4148)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 160, 218)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 420)
[M::mem_pestat] mean and std.dev: (173.15, 73.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 521)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (266, 453, 970)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2378)
[M::mem_pestat] mean and std.dev: (579.11, 545.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3082)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 294, 2052)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5778)
[M::mem_pestat] mean and std.dev: (1112.40, 1574.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7641)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 750844 reads in 202.113 CPU sec, 6.536 real sec
[M::process] read 748198 sequences (100000164 bp) in 2.428 CPU sec, 2.457 real sec...
[M::mem_process_seqs] Processed 750176 reads in 141.954 CPU sec, 4.690 real sec
sorting block 36, #reads = 1117224 mem = 536880554 peak = 1017323520
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 302080, 13, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 217, 478)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1076)
[M::mem_pestat] mean and std.dev: (280.91, 234.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1375)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 161, 219)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 421)
[M::mem_pestat] mean and std.dev: (174.05, 73.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 522)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (517, 598, 1079)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2203)
[M::mem_pestat] mean and std.dev: (648.75, 452.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2765)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 462, 857)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2125)
[M::mem_pestat] mean and std.dev: (516.58, 409.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2759)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 748210 sequences (100000235 bp) in 2.702 CPU sec, 3.251 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 302277, 19, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (124, 165, 639)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1669)
[M::mem_pestat] mean and std.dev: (310.97, 305.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2184)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 161, 219)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 421)
[M::mem_pestat] mean and std.dev: (174.21, 73.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 522)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (487, 744, 1197)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2617)
[M::mem_pestat] mean and std.dev: (769.22, 589.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3327)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 305, 499)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1139)
[M::mem_pestat] mean and std.dev: (306.70, 155.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1459)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 747950 sequences (100000183 bp) in 2.216 CPU sec, 2.220 real sec...
[M::mem_process_seqs] Processed 748742 reads in 204.009 CPU sec, 6.779 real sec
sorting block 37, #reads = 1115386 mem = 536878784 peak = 1017323520
[M::mem_process_seqs] Processed 748198 reads in 140.106 CPU sec, 4.584 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23, 301137, 29, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (311, 731, 2871)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7991)
[M::mem_pestat] mean and std.dev: (1731.43, 1889.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10551)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 161, 218)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 418)
[M::mem_pestat] mean and std.dev: (173.79, 72.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 518)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (142, 430, 1557)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4387)
[M::mem_pestat] mean and std.dev: (674.57, 662.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5802)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 393, 827)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2167)
[M::mem_pestat] mean and std.dev: (503.55, 416.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2837)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 38, #reads = 1115800 mem = 536878574 peak = 1040572416
[M::process] read 748710 sequences (100000112 bp) in 2.847 CPU sec, 3.437 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 301300, 22, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (145, 277, 990)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2680)
[M::mem_pestat] mean and std.dev: (557.09, 630.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3525)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 161, 219)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 421)
[M::mem_pestat] mean and std.dev: (173.85, 73.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 522)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 558, 941)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2423)
[M::mem_pestat] mean and std.dev: (573.05, 493.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3164)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 375, 1003)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2689)
[M::mem_pestat] mean and std.dev: (506.47, 515.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3532)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 748210 reads in 199.919 CPU sec, 6.609 real sec
[M::process] read 748478 sequences (100000268 bp) in 2.395 CPU sec, 2.491 real sec...
[M::mem_process_seqs] Processed 747950 reads in 140.924 CPU sec, 4.735 real sec
sorting block 39, #reads = 1114609 mem = 536877384 peak = 1040572416
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 301597, 23, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (235, 519, 774)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1852)
[M::mem_pestat] mean and std.dev: (443.36, 302.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2391)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 161, 219)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 421)
[M::mem_pestat] mean and std.dev: (173.85, 73.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 522)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (98, 914, 1435)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4109)
[M::mem_pestat] mean and std.dev: (906.64, 995.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5446)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 309, 666)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1660)
[M::mem_pestat] mean and std.dev: (381.09, 287.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2157)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 747826 sequences (100000183 bp) in 2.931 CPU sec, 3.432 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 301172, 30, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 295, 787)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1963)
[M::mem_pestat] mean and std.dev: (401.59, 339.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2551)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 160, 218)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 418)
[M::mem_pestat] mean and std.dev: (173.28, 72.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 518)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 428, 645)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1545)
[M::mem_pestat] mean and std.dev: (430.22, 293.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1995)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 294, 686)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1606)
[M::mem_pestat] mean and std.dev: (419.14, 345.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2066)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 747860 sequences (100000130 bp) in 2.324 CPU sec, 2.380 real sec...
[M::mem_process_seqs] Processed 748710 reads in 206.315 CPU sec, 6.920 real sec
sorting block 40, #reads = 1113600 mem = 536876893 peak = 1040572416
[M::mem_process_seqs] Processed 748478 reads in 144.323 CPU sec, 4.758 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 301131, 26, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 217, 986)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2636)
[M::mem_pestat] mean and std.dev: (525.27, 575.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3461)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (119, 161, 219)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 419)
[M::mem_pestat] mean and std.dev: (173.90, 72.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 519)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 450, 913)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2337)
[M::mem_pestat] mean and std.dev: (424.65, 319.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3049)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 392, 2342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6582)
[M::mem_pestat] mean and std.dev: (969.28, 1285.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8702)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 747158 sequences (100000038 bp) in 2.879 CPU sec, 3.279 real sec...
sorting block 41, #reads = 1112396 mem = 536879515 peak = 1040572416
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 301557, 26, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (127, 340, 620)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1606)
[M::mem_pestat] mean and std.dev: (315.24, 248.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2099)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (119, 161, 219)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 419)
[M::mem_pestat] mean and std.dev: (173.95, 72.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 519)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (137, 674, 1472)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4142)
[M::mem_pestat] mean and std.dev: (734.48, 718.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5477)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 417, 963)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2577)
[M::mem_pestat] mean and std.dev: (544.03, 547.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3384)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 747004 sequences (100000257 bp) in 2.318 CPU sec, 2.324 real sec...
[M::mem_process_seqs] Processed 747826 reads in 204.384 CPU sec, 6.771 real sec
[M::mem_process_seqs] Processed 747860 reads in 141.424 CPU sec, 4.638 real sec
sorting block 42, #reads = 1112953 mem = 536878482 peak = 1040572416
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 301242, 22, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (138, 314, 524)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1296)
[M::mem_pestat] mean and std.dev: (290.31, 244.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1682)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (119, 162, 220)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 422)
[M::mem_pestat] mean and std.dev: (174.73, 73.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 523)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (50, 465, 1338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3914)
[M::mem_pestat] mean and std.dev: (725.80, 931.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5202)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 294, 921)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2309)
[M::mem_pestat] mean and std.dev: (431.47, 387.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3003)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 746656 sequences (100000078 bp) in 2.922 CPU sec, 3.402 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 300681, 22, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 225, 840)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2218)
[M::mem_pestat] mean and std.dev: (453.16, 480.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2907)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (119, 162, 220)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 422)
[M::mem_pestat] mean and std.dev: (174.99, 73.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 523)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 942, 1491)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4031)
[M::mem_pestat] mean and std.dev: (797.32, 743.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5301)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 281, 524)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1136)
[M::mem_pestat] mean and std.dev: (305.38, 143.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1442)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 747158 reads in 200.602 CPU sec, 6.552 real sec
[M::process] read 747074 sequences (100000242 bp) in 2.361 CPU sec, 2.370 real sec...
sorting block 43, #reads = 1113622 mem = 536879599 peak = 1040572416
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 301038, 40, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (132, 217, 549)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1383)
[M::mem_pestat] mean and std.dev: (268.53, 214.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1800)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (119, 162, 221)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 425)
[M::mem_pestat] mean and std.dev: (175.40, 74.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 527)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (146, 473, 1750)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4958)
[M::mem_pestat] mean and std.dev: (886.34, 1082.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6562)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 311, 1209)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3235)
[M::mem_pestat] mean and std.dev: (680.04, 759.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4248)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 746522 sequences (100000074 bp) in 2.548 CPU sec, 2.674 real sec...
[M::mem_process_seqs] Processed 746656 reads in 116.728 CPU sec, 4.044 real sec
[M::mem_process_seqs] Processed 747004 reads in 308.553 CPU sec, 10.273 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 300903, 19, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 435, 1015)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2683)
[M::mem_pestat] mean and std.dev: (672.78, 653.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3517)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (119, 162, 220)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 422)
[M::mem_pestat] mean and std.dev: (174.96, 73.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 523)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (105, 125, 1149)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3237)
[M::mem_pestat] mean and std.dev: (465.39, 513.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4281)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 341, 741)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1807)
[M::mem_pestat] mean and std.dev: (448.37, 386.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2340)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 44, #reads = 1113540 mem = 536879690 peak = 1040572416
[M::process] read 750628 sequences (100000032 bp) in 2.802 CPU sec, 3.348 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 300787, 23, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (140, 222, 611)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1553)
[M::mem_pestat] mean and std.dev: (332.50, 311.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2024)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (119, 162, 221)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 425)
[M::mem_pestat] mean and std.dev: (175.40, 73.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 527)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 520, 1299)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3501)
[M::mem_pestat] mean and std.dev: (838.64, 938.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4602)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 299, 715)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1729)
[M::mem_pestat] mean and std.dev: (382.73, 282.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2236)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 747074 reads in 226.003 CPU sec, 7.344 real sec
[M::mem_process_seqs] Processed 746522 reads in 141.589 CPU sec, 4.583 real sec
[M::process] read 752018 sequences (100000072 bp) in 2.703 CPU sec, 2.858 real sec...
sorting block 45, #reads = 1111861 mem = 536878544 peak = 1040572416
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 302490, 33, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (131, 168, 816)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2186)
[M::mem_pestat] mean and std.dev: (448.71, 463.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2871)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 159, 217)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 417)
[M::mem_pestat] mean and std.dev: (172.77, 73.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 517)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (81, 232, 1367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3939)
[M::mem_pestat] mean and std.dev: (530.48, 686.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5225)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 216, 588)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1436)
[M::mem_pestat] mean and std.dev: (305.03, 247.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1860)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 751784 sequences (100000054 bp) in 2.943 CPU sec, 3.490 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 302664, 14, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 187, 558)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1378)
[M::mem_pestat] mean and std.dev: (274.49, 212.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1788)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 158, 216)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 414)
[M::mem_pestat] mean and std.dev: (171.57, 72.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 513)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (134, 639, 932)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2528)
[M::mem_pestat] mean and std.dev: (494.23, 358.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3326)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 284, 513)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1245)
[M::mem_pestat] mean and std.dev: (352.00, 297.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1611)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 750628 reads in 202.818 CPU sec, 6.646 real sec
[M::mem_process_seqs] Processed 752018 reads in 141.304 CPU sec, 4.612 real sec
sorting block 46, #reads = 1112103 mem = 536880314 peak = 1040572416
[M::process] read 751114 sequences (100000060 bp) in 2.531 CPU sec, 2.873 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 302779, 23, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 420, 763)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1967)
[M::mem_pestat] mean and std.dev: (488.32, 482.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2569)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 159, 216)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 414)
[M::mem_pestat] mean and std.dev: (171.87, 72.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 513)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (135, 501, 875)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2355)
[M::mem_pestat] mean and std.dev: (397.22, 279.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3095)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 396, 785)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1949)
[M::mem_pestat] mean and std.dev: (488.76, 409.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2531)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 47, #reads = 1117947 mem = 536878456 peak = 1040572416
[M::process] read 750268 sequences (100000080 bp) in 2.672 CPU sec, 3.425 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 302666, 27, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (146, 294, 798)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2102)
[M::mem_pestat] mean and std.dev: (428.35, 335.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2754)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 159, 217)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 417)
[M::mem_pestat] mean and std.dev: (172.58, 73.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 517)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (84, 307, 786)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2190)
[M::mem_pestat] mean and std.dev: (408.00, 401.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2892)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (144, 234, 458)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1086)
[M::mem_pestat] mean and std.dev: (276.59, 217.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1400)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 751784 reads in 198.620 CPU sec, 6.546 real sec
[M::mem_process_seqs] Processed 751114 reads in 140.439 CPU sec, 4.587 real sec
[M::process] read 749912 sequences (100000212 bp) in 2.440 CPU sec, 2.561 real sec...
sorting block 48, #reads = 1116870 mem = 536879953 peak = 1040572416
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 302659, 17, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (145, 205, 674)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1732)
[M::mem_pestat] mean and std.dev: (333.05, 276.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2261)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 160, 219)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 423)
[M::mem_pestat] mean and std.dev: (173.74, 74.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 525)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (39, 265, 1495)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4407)
[M::mem_pestat] mean and std.dev: (470.75, 635.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5863)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 296, 987)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2593)
[M::mem_pestat] mean and std.dev: (561.96, 594.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3396)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 747986 sequences (100000105 bp) in 2.900 CPU sec, 3.452 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 302269, 17, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 352, 1234)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3372)
[M::mem_pestat] mean and std.dev: (608.43, 649.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4441)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 160, 219)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 421)
[M::mem_pestat] mean and std.dev: (173.78, 74.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 522)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 314, 907)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2375)
[M::mem_pestat] mean and std.dev: (516.88, 542.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3109)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 336, 672)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1616)
[M::mem_pestat] mean and std.dev: (471.40, 419.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2148)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 750268 reads in 196.335 CPU sec, 6.401 real sec
[M::process] read 748436 sequences (100000090 bp) in 2.583 CPU sec, 2.646 real sec...
sorting block 49, #reads = 1116932 mem = 536880094 peak = 1040572416
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 301427, 15, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 324, 907)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2419)
[M::mem_pestat] mean and std.dev: (508.48, 447.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3175)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 162, 221)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 427)
[M::mem_pestat] mean and std.dev: (175.23, 74.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 530)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (142, 329, 1017)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2767)
[M::mem_pestat] mean and std.dev: (292.92, 267.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3642)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 395, 2157)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6113)
[M::mem_pestat] mean and std.dev: (994.06, 1331.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8091)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 750432 sequences (100000195 bp) in 2.390 CPU sec, 2.432 real sec...
[M::mem_process_seqs] Processed 747986 reads in 115.922 CPU sec, 3.762 real sec
[M::mem_process_seqs] Processed 749912 reads in 313.515 CPU sec, 10.185 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 301940, 25, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 337, 1063)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2847)
[M::mem_pestat] mean and std.dev: (508.52, 469.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3739)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 161, 221)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 427)
[M::mem_pestat] mean and std.dev: (175.18, 75.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 530)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 666, 1098)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2908)
[M::mem_pestat] mean and std.dev: (744.12, 660.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3813)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (302, 818, 1774)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4718)
[M::mem_pestat] mean and std.dev: (1137.71, 1072.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6190)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 50, #reads = 1116397 mem = 536889738 peak = 1040572416
[M::process] read 749674 sequences (100000269 bp) in 2.604 CPU sec, 3.386 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 302337, 15, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (140, 238, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 809)
[M::mem_pestat] mean and std.dev: (225.71, 127.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1032)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 159, 218)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 418)
[M::mem_pestat] mean and std.dev: (172.69, 73.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 518)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (504, 525, 1124)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2364)
[M::mem_pestat] mean and std.dev: (764.21, 613.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3216)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 398, 755)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1949)
[M::mem_pestat] mean and std.dev: (351.75, 247.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2546)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 748436 reads in 222.893 CPU sec, 7.290 real sec
[M::mem_process_seqs] Processed 750432 reads in 139.800 CPU sec, 4.566 real sec
sorting block 51, #reads = 1115535 mem = 536881783 peak = 1040572416
[M::process] read 749140 sequences (100000208 bp) in 2.644 CPU sec, 2.845 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 302263, 21, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (122, 187, 488)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1220)
[M::mem_pestat] mean and std.dev: (286.44, 262.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1586)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 160, 218)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 418)
[M::mem_pestat] mean and std.dev: (173.30, 73.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 518)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (232, 280, 2398)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6730)
[M::mem_pestat] mean and std.dev: (1033.81, 1297.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8896)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 581, 1591)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4471)
[M::mem_pestat] mean and std.dev: (1098.12, 1335.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6439)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 748356 sequences (100000065 bp) in 2.616 CPU sec, 3.180 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 302011, 28, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (226, 421, 1137)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2959)
[M::mem_pestat] mean and std.dev: (660.24, 671.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3870)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 160, 218)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 418)
[M::mem_pestat] mean and std.dev: (173.51, 73.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 518)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 360, 1244)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3432)
[M::mem_pestat] mean and std.dev: (645.77, 794.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4526)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 412, 906)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2334)
[M::mem_pestat] mean and std.dev: (524.16, 493.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3048)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 749674 reads in 199.532 CPU sec, 6.536 real sec
sorting block 52, #reads = 1116999 mem = 536878049 peak = 1040572416
[M::process] read 747982 sequences (100000089 bp) in 2.461 CPU sec, 2.492 real sec...
[M::mem_process_seqs] Processed 749140 reads in 140.947 CPU sec, 4.683 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 301118, 31, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 315, 586)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1368)
[M::mem_pestat] mean and std.dev: (346.05, 234.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1759)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 161, 218)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 418)
[M::mem_pestat] mean and std.dev: (173.64, 72.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 518)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 362, 768)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1874)
[M::mem_pestat] mean and std.dev: (451.41, 407.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2427)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 243, 1676)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4728)
[M::mem_pestat] mean and std.dev: (811.15, 881.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6254)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 53, #reads = 1115640 mem = 536876997 peak = 1075277824
[M::process] read 747950 sequences (100000086 bp) in 2.630 CPU sec, 3.320 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 301185, 35, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (132, 281, 1238)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3450)
[M::mem_pestat] mean and std.dev: (569.33, 638.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4556)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 161, 218)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 418)
[M::mem_pestat] mean and std.dev: (173.60, 72.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 518)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (269, 442, 1305)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3377)
[M::mem_pestat] mean and std.dev: (906.66, 794.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4413)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 291, 661)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1603)
[M::mem_pestat] mean and std.dev: (367.35, 323.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2074)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 748356 reads in 199.481 CPU sec, 6.685 real sec
[M::process] read 747228 sequences (100000265 bp) in 2.421 CPU sec, 2.487 real sec...
[M::mem_process_seqs] Processed 747982 reads in 142.043 CPU sec, 4.623 real sec
sorting block 54, #reads = 1115173 mem = 536884290 peak = 1075277824
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 301619, 20, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 362, 785)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1907)
[M::mem_pestat] mean and std.dev: (421.63, 322.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2468)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 161, 219)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 421)
[M::mem_pestat] mean and std.dev: (174.11, 73.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 522)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 418, 844)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2130)
[M::mem_pestat] mean and std.dev: (339.38, 241.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2773)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 309, 1024)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2736)
[M::mem_pestat] mean and std.dev: (520.57, 564.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3592)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 747592 sequences (100000076 bp) in 2.901 CPU sec, 3.541 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 301044, 22, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (125, 214, 427)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1031)
[M::mem_pestat] mean and std.dev: (255.73, 190.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1333)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (119, 161, 219)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 419)
[M::mem_pestat] mean and std.dev: (174.29, 73.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 519)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 616, 1587)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4383)
[M::mem_pestat] mean and std.dev: (917.55, 1109.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5781)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 410, 1093)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2979)
[M::mem_pestat] mean and std.dev: (560.60, 563.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3922)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 747950 reads in 199.628 CPU sec, 6.569 real sec
[M::process] read 747804 sequences (100000292 bp) in 2.431 CPU sec, 2.493 real sec...
[M::mem_process_seqs] Processed 747228 reads in 141.541 CPU sec, 4.655 real sec
sorting block 55, #reads = 1114226 mem = 536879622 peak = 1075277824
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 301164, 27, 24)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (134, 251, 674)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1754)
[M::mem_pestat] mean and std.dev: (420.48, 429.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2294)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (119, 161, 219)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 419)
[M::mem_pestat] mean and std.dev: (174.19, 73.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 519)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (133, 382, 716)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1882)
[M::mem_pestat] mean and std.dev: (428.92, 431.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2465)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 423, 1286)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3448)
[M::mem_pestat] mean and std.dev: (646.26, 604.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4529)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 747456 sequences (100000027 bp) in 2.732 CPU sec, 3.427 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 301712, 22, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 446, 1174)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3124)
[M::mem_pestat] mean and std.dev: (608.93, 485.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4099)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (119, 161, 219)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 419)
[M::mem_pestat] mean and std.dev: (174.00, 73.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 519)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (504, 725, 1301)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2895)
[M::mem_pestat] mean and std.dev: (830.55, 611.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3692)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 317, 736)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1850)
[M::mem_pestat] mean and std.dev: (386.34, 309.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2407)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 747592 reads in 199.306 CPU sec, 6.559 real sec
sorting block 56, #reads = 1115401 mem = 536890193 peak = 1075277824
[M::process] read 747406 sequences (100000236 bp) in 2.472 CPU sec, 2.570 real sec...
[M::mem_process_seqs] Processed 747804 reads in 140.841 CPU sec, 4.693 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 301103, 35, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 251, 526)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1220)
[M::mem_pestat] mean and std.dev: (345.50, 232.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1567)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (119, 161, 218)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 416)
[M::mem_pestat] mean and std.dev: (173.46, 72.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 515)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (364, 956, 1931)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5065)
[M::mem_pestat] mean and std.dev: (993.59, 889.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6632)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 293, 394)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 864)
[M::mem_pestat] mean and std.dev: (276.72, 185.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1099)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 57, #reads = 1114089 mem = 536882769 peak = 1075277824
[M::process] read 746804 sequences (100000045 bp) in 2.842 CPU sec, 3.475 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 301014, 22, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 411, 1464)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4016)
[M::mem_pestat] mean and std.dev: (834.85, 961.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5292)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (119, 161, 219)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 419)
[M::mem_pestat] mean and std.dev: (174.25, 73.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 519)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (243, 549, 1341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3537)
[M::mem_pestat] mean and std.dev: (644.70, 614.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4635)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 305, 905)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2399)
[M::mem_pestat] mean and std.dev: (439.86, 429.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3146)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 747456 reads in 199.400 CPU sec, 6.816 real sec
[M::mem_process_seqs] Processed 747406 reads in 141.404 CPU sec, 4.618 real sec
[M::process] read 746400 sequences (100000155 bp) in 2.980 CPU sec, 3.218 real sec...
sorting block 58, #reads = 1113759 mem = 536877228 peak = 1075277824
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 301200, 18, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 451, 724)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1744)
[M::mem_pestat] mean and std.dev: (383.00, 302.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2254)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (119, 162, 220)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 422)
[M::mem_pestat] mean and std.dev: (174.96, 73.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 523)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (98, 493, 1367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3905)
[M::mem_pestat] mean and std.dev: (530.60, 549.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5174)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 486, 2419)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6821)
[M::mem_pestat] mean and std.dev: (1286.69, 1456.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9022)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 745772 sequences (100000027 bp) in 2.576 CPU sec, 3.168 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 301121, 17, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 274, 814)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2072)
[M::mem_pestat] mean and std.dev: (455.09, 411.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2701)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (119, 162, 221)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 425)
[M::mem_pestat] mean and std.dev: (175.59, 74.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 527)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (136, 787, 1674)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4750)
[M::mem_pestat] mean and std.dev: (858.76, 745.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6288)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 298, 669)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1691)
[M::mem_pestat] mean and std.dev: (363.34, 299.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2202)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 746804 reads in 198.735 CPU sec, 6.544 real sec
[M::mem_process_seqs] Processed 746400 reads in 140.260 CPU sec, 4.590 real sec
[M::process] read 745916 sequences (100000234 bp) in 2.623 CPU sec, 2.835 real sec...
sorting block 59, #reads = 1113311 mem = 536879983 peak = 1075277824
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 301028, 31, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 312, 765)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1939)
[M::mem_pestat] mean and std.dev: (426.62, 404.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2526)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (119, 163, 221)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 425)
[M::mem_pestat] mean and std.dev: (175.85, 74.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 527)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (96, 268, 1496)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4296)
[M::mem_pestat] mean and std.dev: (525.07, 663.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5696)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 868, 1824)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5082)
[M::mem_pestat] mean and std.dev: (974.55, 808.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6711)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 60, #reads = 1112885 mem = 536881142 peak = 1075277824
[M::process] read 754114 sequences (100000209 bp) in 3.160 CPU sec, 3.635 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 300674, 32, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 265, 546)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1270)
[M::mem_pestat] mean and std.dev: (347.64, 250.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1632)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (119, 163, 221)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 425)
[M::mem_pestat] mean and std.dev: (175.81, 74.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 527)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (133, 579, 1151)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3187)
[M::mem_pestat] mean and std.dev: (555.00, 478.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4205)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 276, 1133)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3055)
[M::mem_pestat] mean and std.dev: (512.74, 528.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4016)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 745772 reads in 199.897 CPU sec, 6.576 real sec
[M::mem_process_seqs] Processed 745916 reads in 140.976 CPU sec, 4.731 real sec
[M::process] read 760030 sequences (100000166 bp) in 2.472 CPU sec, 2.742 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 302987, 31, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (130, 168, 246)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 478)
[M::mem_pestat] mean and std.dev: (171.63, 72.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 594)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (116, 156, 212)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 404)
[M::mem_pestat] mean and std.dev: (168.81, 70.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 500)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (223, 516, 1363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3643)
[M::mem_pestat] mean and std.dev: (798.53, 826.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4783)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 241, 402)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 848)
[M::mem_pestat] mean and std.dev: (265.27, 130.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1071)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 61, #reads = 1112649 mem = 536879722 peak = 1075277824
[M::process] read 758892 sequences (100000102 bp) in 3.357 CPU sec, 3.857 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 305678, 26, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 242, 863)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2255)
[M::mem_pestat] mean and std.dev: (494.11, 520.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2951)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (114, 152, 205)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 387)
[M::mem_pestat] mean and std.dev: (163.66, 66.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 478)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 422, 2010)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5690)
[M::mem_pestat] mean and std.dev: (929.38, 1220.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7530)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 272, 851)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2253)
[M::mem_pestat] mean and std.dev: (477.65, 518.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2954)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 754114 reads in 207.366 CPU sec, 6.904 real sec
[M::mem_process_seqs] Processed 760030 reads in 146.997 CPU sec, 4.830 real sec
[M::process] read 758552 sequences (100000178 bp) in 2.715 CPU sec, 2.784 real sec...
sorting block 62, #reads = 1113618 mem = 536881089 peak = 1075277824
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 305400, 17, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (136, 184, 634)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1630)
[M::mem_pestat] mean and std.dev: (323.83, 268.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2128)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (114, 153, 206)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 390)
[M::mem_pestat] mean and std.dev: (164.53, 66.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 482)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (226, 573, 1257)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3319)
[M::mem_pestat] mean and std.dev: (730.56, 772.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4350)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 256, 798)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2086)
[M::mem_pestat] mean and std.dev: (434.38, 428.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2730)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 757122 sequences (100000187 bp) in 2.744 CPU sec, 3.437 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 305135, 33, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (139, 356, 724)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1894)
[M::mem_pestat] mean and std.dev: (382.96, 344.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2479)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (114, 153, 207)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 393)
[M::mem_pestat] mean and std.dev: (165.20, 67.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 486)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 607, 1585)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4339)
[M::mem_pestat] mean and std.dev: (718.40, 805.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5716)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 388, 1181)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3167)
[M::mem_pestat] mean and std.dev: (566.74, 526.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4160)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 758892 reads in 208.557 CPU sec, 6.752 real sec
[M::process] read 755766 sequences (100000245 bp) in 2.400 CPU sec, 2.468 real sec...
sorting block 63, #reads = 1119943 mem = 536883613 peak = 1075277824
[M::mem_process_seqs] Processed 758552 reads in 149.046 CPU sec, 4.852 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 304714, 21, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 267, 626)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1516)
[M::mem_pestat] mean and std.dev: (390.06, 363.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1961)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (115, 154, 209)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 397)
[M::mem_pestat] mean and std.dev: (166.35, 68.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 491)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (39, 931, 3330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9912)
[M::mem_pestat] mean and std.dev: (1422.62, 1449.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13203)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 654, 2051)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5773)
[M::mem_pestat] mean and std.dev: (1195.70, 1490.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7634)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 64, #reads = 1118386 mem = 536878563 peak = 1075277824
[M::process] read 755626 sequences (100000084 bp) in 3.089 CPU sec, 3.514 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 304097, 16, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 394, 897)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2395)
[M::mem_pestat] mean and std.dev: (459.60, 524.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3144)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (115, 155, 211)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 403)
[M::mem_pestat] mean and std.dev: (168.03, 69.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 499)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 496, 1912)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5364)
[M::mem_pestat] mean and std.dev: (882.67, 1055.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7090)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 334, 1289)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3451)
[M::mem_pestat] mean and std.dev: (623.36, 680.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4532)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 757122 reads in 207.205 CPU sec, 6.997 real sec
[M::process] read 755584 sequences (100000290 bp) in 2.501 CPU sec, 2.882 real sec...
[M::mem_process_seqs] Processed 755766 reads in 145.330 CPU sec, 5.111 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 304124, 20, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 321, 963)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2521)
[M::mem_pestat] mean and std.dev: (606.50, 610.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3300)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (115, 156, 211)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 403)
[M::mem_pestat] mean and std.dev: (168.31, 70.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 499)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (140, 914, 2085)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5975)
[M::mem_pestat] mean and std.dev: (1014.53, 1165.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7920)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 243, 701)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1673)
[M::mem_pestat] mean and std.dev: (453.89, 464.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2311)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 65, #reads = 1117504 mem = 536881474 peak = 1075277824
[M::process] read 757660 sequences (100000170 bp) in 3.136 CPU sec, 3.662 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 303781, 16, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 383, 869)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2305)
[M::mem_pestat] mean and std.dev: (533.87, 501.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3023)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (115, 155, 211)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 403)
[M::mem_pestat] mean and std.dev: (168.15, 70.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 499)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (418, 735, 2085)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5419)
[M::mem_pestat] mean and std.dev: (1329.81, 1257.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7086)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (141, 247, 831)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2211)
[M::mem_pestat] mean and std.dev: (483.09, 516.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2901)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 755626 reads in 205.348 CPU sec, 6.995 real sec
[M::mem_process_seqs] Processed 755584 reads in 146.122 CPU sec, 4.873 real sec
[M::process] read 757472 sequences (100000113 bp) in 2.714 CPU sec, 2.875 real sec...
sorting block 66, #reads = 1117834 mem = 536879248 peak = 1075277824
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 304768, 23, 22)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 346, 1186)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3248)
[M::mem_pestat] mean and std.dev: (653.48, 700.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4279)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (115, 154, 208)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 394)
[M::mem_pestat] mean and std.dev: (165.95, 68.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 487)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 720, 1498)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4170)
[M::mem_pestat] mean and std.dev: (826.91, 778.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5506)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 457, 822)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2162)
[M::mem_pestat] mean and std.dev: (417.32, 352.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2832)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 756980 sequences (100000073 bp) in 3.267 CPU sec, 3.844 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 304622, 22, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 244, 673)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1719)
[M::mem_pestat] mean and std.dev: (357.31, 346.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2242)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (115, 154, 208)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 394)
[M::mem_pestat] mean and std.dev: (165.88, 67.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 487)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (140, 549, 572)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1436)
[M::mem_pestat] mean and std.dev: (405.90, 315.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1868)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 430, 807)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2049)
[M::mem_pestat] mean and std.dev: (451.50, 349.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2670)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 757660 reads in 212.450 CPU sec, 7.056 real sec
sorting block 67, #reads = 1118907 mem = 536880381 peak = 1075277824
[M::mem_process_seqs] Processed 757472 reads in 151.351 CPU sec, 4.953 real sec
[M::process] read 756916 sequences (100000101 bp) in 2.454 CPU sec, 2.540 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 304391, 25, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 292, 543)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1331)
[M::mem_pestat] mean and std.dev: (313.48, 220.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1725)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (115, 154, 208)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 394)
[M::mem_pestat] mean and std.dev: (166.06, 68.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 487)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (238, 356, 645)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1459)
[M::mem_pestat] mean and std.dev: (385.70, 264.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1866)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 274, 449)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1001)
[M::mem_pestat] mean and std.dev: (286.20, 164.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1277)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 68, #reads = 1116176 mem = 536878742 peak = 1075277824
[M::process] read 755090 sequences (100000030 bp) in 2.803 CPU sec, 3.446 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 304479, 21, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 224, 919)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2429)
[M::mem_pestat] mean and std.dev: (495.61, 473.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3184)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (115, 154, 209)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 397)
[M::mem_pestat] mean and std.dev: (166.72, 68.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 491)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (327, 580, 1608)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4170)
[M::mem_pestat] mean and std.dev: (752.60, 634.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5451)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (122, 186, 666)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1754)
[M::mem_pestat] mean and std.dev: (327.29, 304.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2298)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 756980 reads in 216.633 CPU sec, 7.142 real sec
[M::process] read 753502 sequences (100000097 bp) in 2.386 CPU sec, 2.416 real sec...
[M::mem_process_seqs] Processed 756916 reads in 154.504 CPU sec, 5.207 real sec
sorting block 69, #reads = 1115052 mem = 536887993 peak = 1075277824
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 303992, 17, 23)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 287, 1057)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2809)
[M::mem_pestat] mean and std.dev: (711.88, 752.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3723)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (115, 156, 211)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 403)
[M::mem_pestat] mean and std.dev: (168.20, 69.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 499)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 521, 976)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2526)
[M::mem_pestat] mean and std.dev: (526.50, 366.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3301)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 272, 1006)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2660)
[M::mem_pestat] mean and std.dev: (518.82, 613.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3487)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 757226 sequences (100000105 bp) in 2.930 CPU sec, 3.680 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 303017, 28, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 330, 1906)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5326)
[M::mem_pestat] mean and std.dev: (872.85, 1017.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7036)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (116, 157, 213)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 407)
[M::mem_pestat] mean and std.dev: (169.79, 70.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 504)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (102, 422, 782)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2142)
[M::mem_pestat] mean and std.dev: (389.36, 387.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2822)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 545, 1235)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3307)
[M::mem_pestat] mean and std.dev: (792.53, 736.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4343)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 755090 reads in 209.725 CPU sec, 6.997 real sec
[M::process] read 754072 sequences (100000199 bp) in 2.586 CPU sec, 2.685 real sec...
[M::mem_process_seqs] Processed 753502 reads in 147.490 CPU sec, 4.799 real sec
sorting block 70, #reads = 1115684 mem = 536880552 peak = 1075277824
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 303922, 31, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 309, 902)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2410)
[M::mem_pestat] mean and std.dev: (340.00, 280.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3164)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (115, 155, 210)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 400)
[M::mem_pestat] mean and std.dev: (166.99, 69.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 495)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (584, 1116, 1678)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3866)
[M::mem_pestat] mean and std.dev: (1177.03, 981.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5102)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 262, 871)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2263)
[M::mem_pestat] mean and std.dev: (439.39, 509.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2959)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 752338 sequences (100000168 bp) in 3.001 CPU sec, 3.386 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 303456, 22, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 231, 455)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1043)
[M::mem_pestat] mean and std.dev: (271.60, 163.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1337)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (116, 156, 212)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 404)
[M::mem_pestat] mean and std.dev: (168.91, 70.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 500)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (128, 677, 1319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3701)
[M::mem_pestat] mean and std.dev: (930.62, 1119.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5410)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (236, 437, 1660)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4508)
[M::mem_pestat] mean and std.dev: (865.56, 989.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5932)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 751406 sequences (100000149 bp) in 2.430 CPU sec, 2.537 real sec...
[M::mem_process_seqs] Processed 757226 reads in 239.674 CPU sec, 8.068 real sec
sorting block 71, #reads = 1116264 mem = 536879990 peak = 1075277824
[M::mem_process_seqs] Processed 754072 reads in 164.996 CPU sec, 5.474 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 302588, 22, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 383, 1516)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4240)
[M::mem_pestat] mean and std.dev: (941.20, 1152.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5602)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 157, 214)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 408)
[M::mem_pestat] mean and std.dev: (170.22, 70.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 505)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (245, 485, 1082)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2756)
[M::mem_pestat] mean and std.dev: (495.22, 389.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3593)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (243, 319, 778)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1848)
[M::mem_pestat] mean and std.dev: (396.53, 315.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2383)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 72, #reads = 1106956 mem = 536876648 peak = 1075277824
[M::process] read 751932 sequences (100000228 bp) in 3.017 CPU sec, 3.582 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 302315, 33, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 218, 1375)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3825)
[M::mem_pestat] mean and std.dev: (709.14, 810.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5050)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 158, 215)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 411)
[M::mem_pestat] mean and std.dev: (170.85, 71.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 509)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (237, 608, 1312)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3462)
[M::mem_pestat] mean and std.dev: (810.28, 817.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4537)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 227, 625)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1573)
[M::mem_pestat] mean and std.dev: (384.79, 336.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2047)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 752338 reads in 223.205 CPU sec, 7.524 real sec
[M::process] read 750990 sequences (100000045 bp) in 2.479 CPU sec, 2.500 real sec...
[M::mem_process_seqs] Processed 751406 reads in 155.162 CPU sec, 5.415 real sec
sorting block 73, #reads = 1108374 mem = 536885655 peak = 1075277824
[M::process] read 751516 sequences (100000165 bp) in 2.983 CPU sec, 3.574 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 301745, 18, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 242, 1396)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3850)
[M::mem_pestat] mean and std.dev: (476.57, 547.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5077)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 158, 215)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 411)
[M::mem_pestat] mean and std.dev: (171.14, 71.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 509)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 932, 2391)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6879)
[M::mem_pestat] mean and std.dev: (1119.06, 1009.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9123)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 394, 928)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2394)
[M::mem_pestat] mean and std.dev: (557.68, 481.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3127)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 750570 sequences (100000186 bp) in 2.459 CPU sec, 2.468 real sec...
[M::mem_process_seqs] Processed 750990 reads in 132.436 CPU sec, 4.259 real sec
sorting block 74, #reads = 1109812 mem = 536883208 peak = 1075277824
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 302420, 23, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 291, 786)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2058)
[M::mem_pestat] mean and std.dev: (490.47, 487.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2694)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 158, 214)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 408)
[M::mem_pestat] mean and std.dev: (170.48, 70.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 505)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 707, 1337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3611)
[M::mem_pestat] mean and std.dev: (906.90, 961.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4752)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 287, 732)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1836)
[M::mem_pestat] mean and std.dev: (447.81, 350.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2388)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 302700, 24, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 482, 1047)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2817)
[M::mem_pestat] mean and std.dev: (718.17, 694.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3702)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 158, 214)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 408)
[M::mem_pestat] mean and std.dev: (170.40, 70.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 505)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (30, 282, 1185)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3495)
[M::mem_pestat] mean and std.dev: (695.58, 862.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4650)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 256, 895)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2331)
[M::mem_pestat] mean and std.dev: (531.11, 529.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3049)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 751932 reads in 348.747 CPU sec, 11.604 real sec
[M::mem_process_seqs] Processed 751516 reads in 188.830 CPU sec, 6.135 real sec
[M::process] read 765658 sequences (100000054 bp) in 3.089 CPU sec, 3.382 real sec...
sorting block 75, #reads = 1110612 mem = 536876782 peak = 1075277824
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 301787, 26, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (133, 283, 627)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1615)
[M::mem_pestat] mean and std.dev: (392.22, 353.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2109)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 159, 214)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 408)
[M::mem_pestat] mean and std.dev: (170.84, 70.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 505)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (245, 892, 1461)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3893)
[M::mem_pestat] mean and std.dev: (824.29, 589.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5109)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 259, 708)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1772)
[M::mem_pestat] mean and std.dev: (438.72, 425.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2304)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 761098 sequences (100000014 bp) in 3.161 CPU sec, 3.954 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 306506, 18, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 259, 1312)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3604)
[M::mem_pestat] mean and std.dev: (627.40, 710.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4750)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (112, 149, 200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 376)
[M::mem_pestat] mean and std.dev: (160.12, 64.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 464)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (257, 646, 1639)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4403)
[M::mem_pestat] mean and std.dev: (678.44, 595.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5785)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 266, 509)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1163)
[M::mem_pestat] mean and std.dev: (300.52, 209.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1490)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 750570 reads in 234.076 CPU sec, 7.630 real sec
[M::process] read 758574 sequences (100000069 bp) in 2.663 CPU sec, 2.893 real sec...
sorting block 76, #reads = 1108747 mem = 536884662 peak = 1075277824
[M::mem_process_seqs] Processed 765658 reads in 174.791 CPU sec, 5.682 real sec
sorting block 77, #reads = 1109585 mem = 536882934 peak = 1075277824
[M::process] read 759292 sequences (100000245 bp) in 2.847 CPU sec, 3.765 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 304722, 13, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 241, 1024)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2708)
[M::mem_pestat] mean and std.dev: (487.93, 483.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3550)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (114, 153, 207)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 393)
[M::mem_pestat] mean and std.dev: (165.43, 67.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 486)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (234, 540, 1683)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4581)
[M::mem_pestat] mean and std.dev: (1034.38, 1033.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6030)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 413, 1113)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2985)
[M::mem_pestat] mean and std.dev: (650.49, 587.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3921)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 756846 sequences (100000067 bp) in 2.338 CPU sec, 2.426 real sec...
[M::mem_process_seqs] Processed 758574 reads in 132.961 CPU sec, 4.402 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 305657, 32, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (129, 339, 902)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2448)
[M::mem_pestat] mean and std.dev: (445.89, 511.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3221)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (113, 152, 204)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 386)
[M::mem_pestat] mean and std.dev: (163.31, 66.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 477)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (104, 636, 1180)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3332)
[M::mem_pestat] mean and std.dev: (698.97, 758.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4408)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 444, 1464)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4028)
[M::mem_pestat] mean and std.dev: (592.02, 591.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5310)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 305098, 24, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (249, 527, 1690)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4572)
[M::mem_pestat] mean and std.dev: (834.05, 731.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6013)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (114, 153, 206)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 390)
[M::mem_pestat] mean and std.dev: (164.84, 67.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 482)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (257, 522, 992)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2462)
[M::mem_pestat] mean and std.dev: (462.80, 356.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3197)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 297, 555)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1329)
[M::mem_pestat] mean and std.dev: (290.97, 174.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1716)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 761098 reads in 355.957 CPU sec, 11.749 real sec
[M::process] read 755938 sequences (100000025 bp) in 2.709 CPU sec, 2.954 real sec...
sorting block 78, #reads = 1113366 mem = 536881018 peak = 1075277824
[M::mem_process_seqs] Processed 759292 reads in 193.335 CPU sec, 6.693 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 304583, 19, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 370, 654)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1638)
[M::mem_pestat] mean and std.dev: (378.93, 285.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2130)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (115, 155, 209)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 397)
[M::mem_pestat] mean and std.dev: (166.95, 68.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 491)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (129, 180, 276)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 570)
[M::mem_pestat] mean and std.dev: (165.00, 70.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 717)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 240, 638)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1594)
[M::mem_pestat] mean and std.dev: (349.24, 240.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2072)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 79, #reads = 1113644 mem = 536880279 peak = 1089437696
[M::process] read 755068 sequences (100000255 bp) in 2.987 CPU sec, 3.660 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 304054, 26, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 232, 757)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1967)
[M::mem_pestat] mean and std.dev: (501.62, 557.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2730)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (115, 155, 210)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 400)
[M::mem_pestat] mean and std.dev: (167.56, 69.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 495)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 381, 756)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1830)
[M::mem_pestat] mean and std.dev: (495.88, 475.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2400)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 292, 897)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2363)
[M::mem_pestat] mean and std.dev: (486.57, 449.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3096)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 756846 reads in 219.528 CPU sec, 7.451 real sec
[M::process] read 756566 sequences (100000124 bp) in 2.515 CPU sec, 2.658 real sec...
[M::mem_process_seqs] Processed 755938 reads in 153.283 CPU sec, 5.004 real sec
sorting block 80, #reads = 1114049 mem = 536885670 peak = 1089437696
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 303992, 20, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (134, 251, 504)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1244)
[M::mem_pestat] mean and std.dev: (334.07, 271.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1614)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (116, 155, 210)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 398)
[M::mem_pestat] mean and std.dev: (167.73, 69.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 492)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (90, 649, 1498)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4314)
[M::mem_pestat] mean and std.dev: (750.42, 777.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5722)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 354, 981)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2521)
[M::mem_pestat] mean and std.dev: (501.85, 425.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3291)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 756288 sequences (100000019 bp) in 2.863 CPU sec, 3.551 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 304490, 14, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 185, 560)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1384)
[M::mem_pestat] mean and std.dev: (299.76, 254.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1796)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (115, 155, 209)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 397)
[M::mem_pestat] mean and std.dev: (166.61, 68.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 491)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (489, 608, 1476)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3450)
[M::mem_pestat] mean and std.dev: (811.75, 830.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4437)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 322, 1270)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3430)
[M::mem_pestat] mean and std.dev: (713.76, 822.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4510)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 755068 reads in 210.415 CPU sec, 7.098 real sec
[M::process] read 755870 sequences (100000067 bp) in 2.377 CPU sec, 2.555 real sec...
[M::mem_process_seqs] Processed 756566 reads in 149.897 CPU sec, 5.080 real sec
sorting block 81, #reads = 1114997 mem = 536878790 peak = 1089437696
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 304303, 27, 22)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (146, 571, 877)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2339)
[M::mem_pestat] mean and std.dev: (536.58, 502.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3070)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (115, 155, 209)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 397)
[M::mem_pestat] mean and std.dev: (166.97, 68.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 491)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 430, 1893)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5377)
[M::mem_pestat] mean and std.dev: (1069.89, 1248.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7119)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 370, 549)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1321)
[M::mem_pestat] mean and std.dev: (310.32, 186.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1707)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 754986 sequences (100000080 bp) in 2.918 CPU sec, 3.393 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23, 303812, 34, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 207, 529)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1263)
[M::mem_pestat] mean and std.dev: (266.21, 219.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1630)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (115, 155, 210)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 400)
[M::mem_pestat] mean and std.dev: (167.58, 69.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 495)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (530, 982, 1514)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3482)
[M::mem_pestat] mean and std.dev: (1062.15, 787.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4466)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 276, 1168)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3136)
[M::mem_pestat] mean and std.dev: (617.88, 620.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4120)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 754810 sequences (100000226 bp) in 2.414 CPU sec, 2.421 real sec...
[M::mem_process_seqs] Processed 756288 reads in 213.017 CPU sec, 7.162 real sec
sorting block 82, #reads = 1117528 mem = 536882907 peak = 1089437696
[M::mem_process_seqs] Processed 755870 reads in 146.169 CPU sec, 4.839 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 304132, 20, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 381, 781)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1901)
[M::mem_pestat] mean and std.dev: (494.13, 500.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2494)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (116, 156, 211)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 401)
[M::mem_pestat] mean and std.dev: (167.95, 69.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 496)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (30, 382, 1167)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3441)
[M::mem_pestat] mean and std.dev: (471.16, 538.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4578)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 280, 613)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1517)
[M::mem_pestat] mean and std.dev: (418.09, 357.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1969)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 83, #reads = 1115916 mem = 536877988 peak = 1089437696
[M::process] read 754008 sequences (100000174 bp) in 3.070 CPU sec, 3.475 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 303794, 16, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 224, 836)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2206)
[M::mem_pestat] mean and std.dev: (459.12, 491.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2891)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (116, 156, 211)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 401)
[M::mem_pestat] mean and std.dev: (167.96, 69.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 496)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 509, 660)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1578)
[M::mem_pestat] mean and std.dev: (388.71, 273.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2037)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 658, 1097)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2837)
[M::mem_pestat] mean and std.dev: (672.73, 492.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3707)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 754986 reads in 214.471 CPU sec, 7.236 real sec
[M::process] read 757614 sequences (100000090 bp) in 2.486 CPU sec, 2.535 real sec...
[M::mem_process_seqs] Processed 754810 reads in 153.878 CPU sec, 5.078 real sec
sorting block 84, #reads = 1115905 mem = 536879076 peak = 1089437696
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 303187, 22, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (142, 246, 801)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2119)
[M::mem_pestat] mean and std.dev: (392.53, 380.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2778)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (116, 156, 212)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 404)
[M::mem_pestat] mean and std.dev: (168.87, 70.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 500)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (129, 471, 1919)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5499)
[M::mem_pestat] mean and std.dev: (1046.09, 1220.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7289)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 385, 571)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1359)
[M::mem_pestat] mean and std.dev: (384.36, 264.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1753)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 751278 sequences (100000040 bp) in 2.893 CPU sec, 3.454 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 303868, 22, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 418, 1016)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2682)
[M::mem_pestat] mean and std.dev: (644.97, 674.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3515)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (115, 154, 208)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 394)
[M::mem_pestat] mean and std.dev: (165.93, 67.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 487)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (75, 244, 755)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2115)
[M::mem_pestat] mean and std.dev: (414.00, 414.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2795)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 283, 1087)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2883)
[M::mem_pestat] mean and std.dev: (630.36, 683.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3781)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 751424 sequences (100000047 bp) in 2.391 CPU sec, 2.503 real sec...
[M::mem_process_seqs] Processed 754008 reads in 234.858 CPU sec, 7.713 real sec
sorting block 85, #reads = 1113462 mem = 536879338 peak = 1089437696
[M::mem_process_seqs] Processed 757614 reads in 178.395 CPU sec, 5.971 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 302241, 22, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 241, 918)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2404)
[M::mem_pestat] mean and std.dev: (469.90, 415.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3147)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 158, 214)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 408)
[M::mem_pestat] mean and std.dev: (170.55, 70.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 505)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (265, 823, 1784)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4822)
[M::mem_pestat] mean and std.dev: (815.26, 799.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6341)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 255, 986)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2576)
[M::mem_pestat] mean and std.dev: (519.96, 478.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3371)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 750756 sequences (100000081 bp) in 2.834 CPU sec, 3.540 real sec...
sorting block 86, #reads = 1104422 mem = 536879550 peak = 1089437696
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 302248, 28, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (126, 201, 881)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2391)
[M::mem_pestat] mean and std.dev: (452.00, 445.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3146)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 158, 214)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 408)
[M::mem_pestat] mean and std.dev: (170.50, 70.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 505)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 360, 1074)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2918)
[M::mem_pestat] mean and std.dev: (562.58, 644.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3840)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 324, 852)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2184)
[M::mem_pestat] mean and std.dev: (352.40, 332.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2850)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 751278 reads in 209.788 CPU sec, 7.089 real sec
[M::process] read 751030 sequences (100000289 bp) in 2.443 CPU sec, 2.733 real sec...
[M::mem_process_seqs] Processed 751424 reads in 148.126 CPU sec, 5.057 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 302649, 26, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (137, 315, 703)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1835)
[M::mem_pestat] mean and std.dev: (368.00, 374.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2401)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 158, 214)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 408)
[M::mem_pestat] mean and std.dev: (170.64, 70.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 505)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (112, 724, 1219)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3433)
[M::mem_pestat] mean and std.dev: (566.14, 503.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4540)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 309, 944)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2458)
[M::mem_pestat] mean and std.dev: (675.00, 605.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3215)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 87, #reads = 1113142 mem = 536879289 peak = 1089437696
[M::process] read 751292 sequences (100000284 bp) in 2.934 CPU sec, 3.508 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 302437, 28, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (146, 263, 2090)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5978)
[M::mem_pestat] mean and std.dev: (877.40, 1155.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7922)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 158, 215)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 411)
[M::mem_pestat] mean and std.dev: (170.87, 71.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 509)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (82, 228, 723)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2005)
[M::mem_pestat] mean and std.dev: (280.30, 330.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2646)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 279, 801)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2089)
[M::mem_pestat] mean and std.dev: (418.62, 382.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2733)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 750756 reads in 209.415 CPU sec, 7.016 real sec
[M::process] read 750092 sequences (100000085 bp) in 2.545 CPU sec, 2.569 real sec...
[M::mem_process_seqs] Processed 751030 reads in 147.848 CPU sec, 4.965 real sec
sorting block 88, #reads = 1112980 mem = 536881826 peak = 1089437696
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 302335, 19, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 340, 848)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2214)
[M::mem_pestat] mean and std.dev: (472.77, 394.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2897)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 158, 215)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 411)
[M::mem_pestat] mean and std.dev: (170.93, 71.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 509)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (388, 574, 1098)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2518)
[M::mem_pestat] mean and std.dev: (498.93, 315.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3228)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 368, 918)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2356)
[M::mem_pestat] mean and std.dev: (473.77, 403.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3075)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 750124 sequences (100000182 bp) in 2.958 CPU sec, 3.644 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 301972, 26, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 840, 1626)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4554)
[M::mem_pestat] mean and std.dev: (933.86, 858.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6018)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 159, 215)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 409)
[M::mem_pestat] mean and std.dev: (171.13, 70.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 506)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (473, 1247, 4903)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13763)
[M::mem_pestat] mean and std.dev: (2616.31, 2834.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 18193)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 376, 1343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3721)
[M::mem_pestat] mean and std.dev: (852.47, 908.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4910)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 751292 reads in 211.413 CPU sec, 7.152 real sec
[M::process] read 759628 sequences (100000156 bp) in 2.437 CPU sec, 2.518 real sec...
sorting block 89, #reads = 1113073 mem = 536877888 peak = 1089437696
[M::mem_process_seqs] Processed 750092 reads in 149.306 CPU sec, 5.086 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 301456, 21, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 338, 962)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2574)
[M::mem_pestat] mean and std.dev: (557.38, 591.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3380)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 159, 214)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 408)
[M::mem_pestat] mean and std.dev: (170.88, 70.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 505)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 284, 1159)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3061)
[M::mem_pestat] mean and std.dev: (428.05, 395.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4012)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (143, 284, 896)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2402)
[M::mem_pestat] mean and std.dev: (424.03, 388.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3155)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 90, #reads = 1112973 mem = 536876501 peak = 1089437696
[M::process] read 757854 sequences (100000130 bp) in 2.866 CPU sec, 3.444 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 304649, 18, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (135, 224, 505)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1245)
[M::mem_pestat] mean and std.dev: (344.81, 305.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1615)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (114, 152, 205)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 387)
[M::mem_pestat] mean and std.dev: (163.93, 66.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 478)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 354, 1126)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3040)
[M::mem_pestat] mean and std.dev: (534.62, 614.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3997)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 248, 982)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2644)
[M::mem_pestat] mean and std.dev: (468.85, 493.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3475)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 756564 sequences (100000227 bp) in 2.433 CPU sec, 2.535 real sec...
[M::mem_process_seqs] Processed 750124 reads in 236.012 CPU sec, 7.964 real sec
[M::mem_process_seqs] Processed 759628 reads in 161.847 CPU sec, 5.342 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 304695, 26, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (144, 447, 777)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2043)
[M::mem_pestat] mean and std.dev: (492.56, 412.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2676)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (115, 154, 208)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 394)
sorting block 91, #reads = 1103393 mem = 536885742 peak = 1089437696
[M::mem_pestat] mean and std.dev: (165.59, 67.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 487)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 552, 1208)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3278)
[M::mem_pestat] mean and std.dev: (860.65, 817.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4313)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (141, 259, 690)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1788)
[M::mem_pestat] mean and std.dev: (391.68, 403.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2337)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 756036 sequences (100000113 bp) in 2.984 CPU sec, 3.588 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 304787, 16, 20)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (131, 198, 1079)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2975)
[M::mem_pestat] mean and std.dev: (376.30, 461.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3923)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (115, 155, 209)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 397)
[M::mem_pestat] mean and std.dev: (166.68, 68.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 491)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 303, 885)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2245)
[M::mem_pestat] mean and std.dev: (424.73, 341.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2925)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 303, 835)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2083)
[M::mem_pestat] mean and std.dev: (452.84, 371.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2707)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 757854 reads in 203.391 CPU sec, 6.838 real sec
[M::mem_process_seqs] Processed 756564 reads in 144.409 CPU sec, 4.809 real sec
[M::process] read 753076 sequences (100000300 bp) in 2.417 CPU sec, 2.882 real sec...
sorting block 92, #reads = 1120926 mem = 536877296 peak = 1089437696
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 304338, 19, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 291, 808)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2126)
[M::mem_pestat] mean and std.dev: (448.64, 462.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2785)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (115, 155, 210)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 400)
[M::mem_pestat] mean and std.dev: (167.26, 69.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 495)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (94, 260, 1565)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4507)
[M::mem_pestat] mean and std.dev: (484.00, 748.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5978)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 484, 1693)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4693)
[M::mem_pestat] mean and std.dev: (1067.74, 1322.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6356)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 753190 sequences (100000064 bp) in 3.110 CPU sec, 3.589 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 302967, 22, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 259, 770)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1928)
[M::mem_pestat] mean and std.dev: (311.30, 211.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2507)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (116, 157, 214)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 410)
[M::mem_pestat] mean and std.dev: (170.25, 71.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 508)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 319, 515)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1105)
[M::mem_pestat] mean and std.dev: (317.53, 233.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1400)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 597, 2347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6599)
[M::mem_pestat] mean and std.dev: (1102.50, 1438.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8725)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 756036 reads in 203.612 CPU sec, 6.687 real sec
[M::process] read 753424 sequences (100000079 bp) in 2.412 CPU sec, 2.499 real sec...
sorting block 93, #reads = 1119553 mem = 536878089 peak = 1089437696
[M::mem_process_seqs] Processed 753076 reads in 143.348 CPU sec, 4.823 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 303313, 14, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (115, 169, 787)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2131)
[M::mem_pestat] mean and std.dev: (376.65, 435.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2803)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (116, 157, 214)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 410)
[M::mem_pestat] mean and std.dev: (170.11, 71.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 508)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 698, 698)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1730)
[M::mem_pestat] mean and std.dev: (532.38, 478.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2446)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 281, 1027)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2729)
[M::mem_pestat] mean and std.dev: (559.64, 608.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3580)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 94, #reads = 1116978 mem = 536879381 peak = 1089437696
[M::process] read 754820 sequences (100000085 bp) in 2.870 CPU sec, 3.492 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 303285, 25, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 471, 1223)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3305)
[M::mem_pestat] mean and std.dev: (651.43, 752.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4346)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (116, 157, 213)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 407)
[M::mem_pestat] mean and std.dev: (169.89, 71.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 504)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 545, 1305)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3613)
[M::mem_pestat] mean and std.dev: (667.48, 636.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4767)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 298, 614)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1488)
[M::mem_pestat] mean and std.dev: (379.80, 268.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1925)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 753190 reads in 200.425 CPU sec, 6.835 real sec
[M::mem_process_seqs] Processed 753424 reads in 141.398 CPU sec, 4.773 real sec
[M::process] read 755772 sequences (100000049 bp) in 2.400 CPU sec, 2.667 real sec...
sorting block 95, #reads = 1117674 mem = 536879008 peak = 1089437696
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 303914, 17, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 277, 810)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2100)
[M::mem_pestat] mean and std.dev: (423.83, 391.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2745)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (116, 156, 211)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 401)
[M::mem_pestat] mean and std.dev: (168.10, 69.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 496)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (342, 558, 2128)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5700)
[M::mem_pestat] mean and std.dev: (1012.29, 905.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7486)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 366, 1303)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3545)
[M::mem_pestat] mean and std.dev: (653.45, 728.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4666)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 754730 sequences (100000205 bp) in 2.830 CPU sec, 3.364 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 304138, 24, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (126, 257, 604)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1560)
[M::mem_pestat] mean and std.dev: (352.33, 304.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2038)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (115, 155, 209)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 397)
[M::mem_pestat] mean and std.dev: (166.93, 68.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 491)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 1126, 2034)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5660)
[M::mem_pestat] mean and std.dev: (1068.86, 1057.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7473)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 224, 1613)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4537)
[M::mem_pestat] mean and std.dev: (764.20, 964.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5999)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 754820 reads in 202.490 CPU sec, 6.722 real sec
[M::process] read 754152 sequences (100000144 bp) in 2.333 CPU sec, 2.516 real sec...
[M::mem_process_seqs] Processed 755772 reads in 143.374 CPU sec, 4.871 real sec
sorting block 96, #reads = 1118459 mem = 536880097 peak = 1089437696
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 304011, 17, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (142, 303, 645)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1651)
[M::mem_pestat] mean and std.dev: (350.74, 298.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2154)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (116, 156, 211)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 401)
[M::mem_pestat] mean and std.dev: (168.01, 69.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 496)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (237, 985, 1830)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5016)
[M::mem_pestat] mean and std.dev: (973.56, 882.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6609)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 277, 1059)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2849)
[M::mem_pestat] mean and std.dev: (500.19, 514.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3744)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 752568 sequences (100000108 bp) in 2.766 CPU sec, 3.333 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 303796, 18, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (139, 422, 713)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1861)
[M::mem_pestat] mean and std.dev: (367.87, 235.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2435)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (116, 156, 212)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 404)
[M::mem_pestat] mean and std.dev: (168.70, 70.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 500)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (74, 213, 437)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1163)
[M::mem_pestat] mean and std.dev: (288.53, 273.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1526)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 286, 1705)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4773)
[M::mem_pestat] mean and std.dev: (752.37, 1043.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6307)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 754730 reads in 203.132 CPU sec, 6.797 real sec
sorting block 97, #reads = 1117840 mem = 536880680 peak = 1089437696
[M::mem_process_seqs] Processed 754152 reads in 144.152 CPU sec, 4.723 real sec
[M::process] read 751060 sequences (100000093 bp) in 2.445 CPU sec, 2.822 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 303102, 28, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (342, 584, 1634)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4218)
[M::mem_pestat] mean and std.dev: (841.95, 867.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5510)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (116, 157, 213)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 407)
[M::mem_pestat] mean and std.dev: (169.63, 70.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 504)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 451, 967)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2603)
[M::mem_pestat] mean and std.dev: (469.16, 447.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3421)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 551, 1760)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4952)
[M::mem_pestat] mean and std.dev: (1079.29, 1268.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6548)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 98, #reads = 1117571 mem = 536879750 peak = 1119760384
[M::process] read 750544 sequences (100000110 bp) in 2.642 CPU sec, 3.321 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 302156, 30, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 379, 1205)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3221)
[M::mem_pestat] mean and std.dev: (817.93, 818.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4229)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 158, 215)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 411)
[M::mem_pestat] mean and std.dev: (170.84, 71.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 509)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (276, 1175, 1781)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4791)
[M::mem_pestat] mean and std.dev: (1106.93, 966.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6296)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 350, 863)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2279)
[M::mem_pestat] mean and std.dev: (454.54, 400.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2987)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 752568 reads in 206.943 CPU sec, 6.810 real sec
[M::process] read 751486 sequences (100000078 bp) in 2.579 CPU sec, 2.731 real sec...
[M::mem_process_seqs] Processed 751060 reads in 147.311 CPU sec, 4.926 real sec
sorting block 99, #reads = 1115899 mem = 536878092 peak = 1119760384
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 301851, 27, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 324, 1177)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3201)
[M::mem_pestat] mean and std.dev: (733.46, 769.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4213)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 159, 215)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 411)
[M::mem_pestat] mean and std.dev: (171.05, 71.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 509)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 597, 1403)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3901)
[M::mem_pestat] mean and std.dev: (829.08, 811.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5150)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 328, 1344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3700)
[M::mem_pestat] mean and std.dev: (816.69, 1089.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5175)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 751392 sequences (100000206 bp) in 2.829 CPU sec, 3.497 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 302674, 27, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 237, 836)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2206)
[M::mem_pestat] mean and std.dev: (399.33, 396.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2891)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 158, 214)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 408)
[M::mem_pestat] mean and std.dev: (170.32, 70.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 505)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (441, 733, 2794)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7500)
[M::mem_pestat] mean and std.dev: (1789.33, 1906.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9853)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 307, 809)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2035)
[M::mem_pestat] mean and std.dev: (499.28, 395.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2648)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 750544 reads in 210.355 CPU sec, 7.022 real sec
[M::process] read 750758 sequences (100000150 bp) in 2.693 CPU sec, 2.754 real sec...
[M::mem_process_seqs] Processed 751486 reads in 154.373 CPU sec, 5.044 real sec
sorting block 100, #reads = 1114626 mem = 536880082 peak = 1119760384
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 302116, 24, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 319, 772)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1882)
[M::mem_pestat] mean and std.dev: (457.43, 372.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2437)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 158, 214)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 408)
[M::mem_pestat] mean and std.dev: (170.47, 70.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 505)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (226, 484, 2156)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6016)
[M::mem_pestat] mean and std.dev: (971.00, 1233.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7946)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 293, 655)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1603)
[M::mem_pestat] mean and std.dev: (410.35, 320.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2077)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 750886 sequences (100000212 bp) in 2.887 CPU sec, 3.635 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 302408, 22, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 877, 2168)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6118)
[M::mem_pestat] mean and std.dev: (924.00, 858.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8093)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 158, 214)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 408)
[M::mem_pestat] mean and std.dev: (170.39, 70.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 505)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (111, 382, 1562)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4464)
[M::mem_pestat] mean and std.dev: (984.86, 1152.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5915)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 206, 409)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 903)
[M::mem_pestat] mean and std.dev: (291.50, 196.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1150)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 751392 reads in 212.089 CPU sec, 7.053 real sec
[M::process] read 751076 sequences (100000153 bp) in 2.398 CPU sec, 2.398 real sec...
sorting block 101, #reads = 1111737 mem = 536880845 peak = 1119760384
[M::mem_process_seqs] Processed 750758 reads in 149.994 CPU sec, 5.108 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 302546, 27, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (143, 253, 869)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2321)
[M::mem_pestat] mean and std.dev: (396.36, 440.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3047)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 158, 214)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 408)
[M::mem_pestat] mean and std.dev: (170.39, 70.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 505)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (338, 674, 1341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3347)
[M::mem_pestat] mean and std.dev: (787.12, 824.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4350)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 240, 1202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3290)
[M::mem_pestat] mean and std.dev: (506.54, 573.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4334)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 102, #reads = 1112861 mem = 536878106 peak = 1119760384
[M::process] read 751070 sequences (100000192 bp) in 3.112 CPU sec, 3.443 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 301719, 35, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 219, 1158)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3172)
[M::mem_pestat] mean and std.dev: (552.28, 634.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4179)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 158, 213)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 405)
[M::mem_pestat] mean and std.dev: (169.76, 69.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 501)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 403, 1270)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3384)
[M::mem_pestat] mean and std.dev: (615.30, 627.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4441)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (142, 200, 699)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1813)
[M::mem_pestat] mean and std.dev: (370.84, 341.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2370)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 750886 reads in 200.890 CPU sec, 6.715 real sec
[M::process] read 750926 sequences (100000264 bp) in 2.429 CPU sec, 2.434 real sec...
[M::mem_process_seqs] Processed 751076 reads in 137.144 CPU sec, 4.379 real sec
sorting block 103, #reads = 1113723 mem = 536878312 peak = 1119760384
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 302147, 25, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (139, 203, 478)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1156)
[M::mem_pestat] mean and std.dev: (262.69, 227.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1495)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 158, 213)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 405)
[M::mem_pestat] mean and std.dev: (170.00, 69.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 501)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (394, 641, 1678)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4246)
[M::mem_pestat] mean and std.dev: (955.71, 823.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5530)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 342, 1893)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5303)
[M::mem_pestat] mean and std.dev: (700.06, 935.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7008)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 751464 sequences (100000218 bp) in 2.895 CPU sec, 2.947 real sec...
[M::process] read 762530 sequences (100000134 bp) in 2.020 CPU sec, 2.019 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 301961, 31, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 467, 1334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3700)
[M::mem_pestat] mean and std.dev: (694.82, 866.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4883)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 158, 213)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 405)
[M::mem_pestat] mean and std.dev: (169.93, 69.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 501)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (109, 268, 1383)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3931)
[M::mem_pestat] mean and std.dev: (585.21, 644.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5205)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 488, 1064)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2864)
[M::mem_pestat] mean and std.dev: (674.62, 634.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3764)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 751070 reads in 198.681 CPU sec, 6.318 real sec
sorting block 104, #reads = 1111673 mem = 536882320 peak = 1119760384
[M::mem_process_seqs] Processed 750926 reads in 139.301 CPU sec, 4.459 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 301662, 23, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 238, 773)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1997)
[M::mem_pestat] mean and std.dev: (377.81, 332.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2609)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 158, 213)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 405)
[M::mem_pestat] mean and std.dev: (169.91, 69.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 501)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (132, 688, 1730)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4926)
[M::mem_pestat] mean and std.dev: (1123.17, 1228.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6524)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 269, 857)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2261)
[M::mem_pestat] mean and std.dev: (477.38, 459.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2963)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 105, #reads = 1110113 mem = 536877252 peak = 1119760384
[M::process] read 758976 sequences (100000274 bp) in 2.752 CPU sec, 3.080 real sec...
[M::process] read 757234 sequences (100000166 bp) in 2.455 CPU sec, 2.461 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 306404, 19, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 288, 952)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2492)
[M::mem_pestat] mean and std.dev: (503.25, 416.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3262)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (113, 151, 202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 380)
[M::mem_pestat] mean and std.dev: (161.65, 64.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 469)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 410, 839)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2097)
[M::mem_pestat] mean and std.dev: (433.94, 333.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2726)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 298, 905)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2401)
[M::mem_pestat] mean and std.dev: (376.03, 306.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3149)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 751464 reads in 239.856 CPU sec, 7.809 real sec
[M::mem_process_seqs] Processed 762530 reads in 163.766 CPU sec, 5.402 real sec
sorting block 106, #reads = 1104215 mem = 536877735 peak = 1119760384
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 304988, 19, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 267, 438)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1014)
[M::mem_pestat] mean and std.dev: (267.58, 158.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1302)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (114, 153, 206)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 390)
[M::mem_pestat] mean and std.dev: (164.64, 67.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 482)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 483, 1918)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5336)
[M::mem_pestat] mean and std.dev: (985.16, 1068.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7045)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 174, 263)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 485)
[M::mem_pestat] mean and std.dev: (182.96, 80.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 596)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 754970 sequences (100000109 bp) in 2.889 CPU sec, 3.088 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 304064, 19, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (136, 186, 319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 685)
[M::mem_pestat] mean and std.dev: (190.53, 95.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 868)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (115, 154, 208)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 394)
[M::mem_pestat] mean and std.dev: (165.94, 67.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 487)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (338, 698, 2682)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7370)
[M::mem_pestat] mean and std.dev: (1388.74, 1513.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9714)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 334, 513)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1221)
[M::mem_pestat] mean and std.dev: (336.34, 223.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1575)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 754764 sequences (100000037 bp) in 2.050 CPU sec, 2.045 real sec...
[M::mem_process_seqs] Processed 758976 reads in 202.061 CPU sec, 6.582 real sec
[M::mem_process_seqs] Processed 757234 reads in 132.116 CPU sec, 4.247 real sec
sorting block 107, #reads = 1115570 mem = 536878831 peak = 1119760384
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 303215, 23, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (136, 342, 705)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1843)
[M::mem_pestat] mean and std.dev: (450.26, 413.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2412)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (116, 156, 211)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 401)
[M::mem_pestat] mean and std.dev: (167.77, 69.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 496)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (269, 494, 1665)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4457)
[M::mem_pestat] mean and std.dev: (1101.48, 1260.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6144)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 218, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 703)
[M::mem_pestat] mean and std.dev: (248.81, 127.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 883)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 753452 sequences (100000090 bp) in 2.710 CPU sec, 2.748 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 303746, 22, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 291, 696)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1734)
[M::mem_pestat] mean and std.dev: (423.93, 372.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2253)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (116, 156, 211)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 401)
[M::mem_pestat] mean and std.dev: (168.14, 69.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 496)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (146, 530, 1717)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4859)
[M::mem_pestat] mean and std.dev: (706.56, 790.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6430)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 336, 1076)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2878)
[M::mem_pestat] mean and std.dev: (616.44, 724.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3779)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 752920 sequences (100000036 bp) in 2.300 CPU sec, 2.301 real sec...
[M::mem_process_seqs] Processed 754970 reads in 189.863 CPU sec, 6.055 real sec
sorting block 108, #reads = 1114884 mem = 536881046 peak = 1119760384
[M::mem_process_seqs] Processed 754764 reads in 133.696 CPU sec, 4.362 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 303171, 11, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 227, 838)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2190)
[M::mem_pestat] mean and std.dev: (408.33, 410.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2866)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (116, 157, 213)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 407)
[M::mem_pestat] mean and std.dev: (169.59, 70.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 504)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 269, 633)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1501)
[M::mem_pestat] mean and std.dev: (233.67, 178.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1935)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 260, 1116)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3090)
[M::mem_pestat] mean and std.dev: (410.44, 446.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4077)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 109, #reads = 1113512 mem = 536880706 peak = 1120260096
[M::process] read 753742 sequences (100000184 bp) in 2.958 CPU sec, 3.202 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 302959, 30, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 276, 593)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1457)
[M::mem_pestat] mean and std.dev: (360.89, 275.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1889)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (116, 157, 214)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 410)
[M::mem_pestat] mean and std.dev: (170.09, 71.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 508)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 1216, 1502)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4178)
[M::mem_pestat] mean and std.dev: (890.25, 761.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5516)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 430, 966)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2556)
[M::mem_pestat] mean and std.dev: (549.87, 525.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3351)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 751710 sequences (100000040 bp) in 2.370 CPU sec, 2.377 real sec...
[M::mem_process_seqs] Processed 753452 reads in 207.712 CPU sec, 6.832 real sec
[M::mem_process_seqs] Processed 752920 reads in 142.876 CPU sec, 4.662 real sec
sorting block 110, #reads = 1114544 mem = 536880416 peak = 1120260096
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 303794, 16, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (133, 371, 829)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2221)
[M::mem_pestat] mean and std.dev: (581.84, 605.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3004)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (116, 157, 213)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 407)
[M::mem_pestat] mean and std.dev: (169.34, 70.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 504)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 285, 804)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2082)
[M::mem_pestat] mean and std.dev: (334.07, 282.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2721)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 349, 1127)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3039)
[M::mem_pestat] mean and std.dev: (660.07, 725.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3995)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 750728 sequences (100000091 bp) in 2.933 CPU sec, 3.165 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 302883, 19, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (117, 271, 1368)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3870)
[M::mem_pestat] mean and std.dev: (573.82, 695.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5121)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 158, 215)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 411)
[M::mem_pestat] mean and std.dev: (170.83, 71.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 509)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (564, 718, 1214)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2514)
[M::mem_pestat] mean and std.dev: (744.11, 461.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3164)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 373, 614)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1532)
[M::mem_pestat] mean and std.dev: (357.49, 242.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1991)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 753742 reads in 202.276 CPU sec, 6.570 real sec
[M::process] read 749324 sequences (100000184 bp) in 2.217 CPU sec, 2.228 real sec...
[M::mem_process_seqs] Processed 751710 reads in 143.167 CPU sec, 4.868 real sec
sorting block 111, #reads = 1116268 mem = 536878693 peak = 1120260096
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 301988, 27, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 560, 1234)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3360)
[M::mem_pestat] mean and std.dev: (640.56, 575.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4423)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 159, 216)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 414)
[M::mem_pestat] mean and std.dev: (171.94, 72.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 513)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 928, 1476)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3986)
[M::mem_pestat] mean and std.dev: (988.26, 740.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5241)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 837, 1614)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4446)
[M::mem_pestat] mean and std.dev: (890.76, 973.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5862)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 748476 sequences (100000176 bp) in 4.038 CPU sec, 4.170 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 301884, 20, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (138, 340, 1251)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3477)
[M::mem_pestat] mean and std.dev: (588.04, 624.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4590)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 160, 217)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 415)
[M::mem_pestat] mean and std.dev: (172.98, 72.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 514)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 350, 526)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1248)
[M::mem_pestat] mean and std.dev: (286.39, 202.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1609)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 412, 1015)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2621)
[M::mem_pestat] mean and std.dev: (681.29, 692.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3450)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 750728 reads in 195.917 CPU sec, 6.553 real sec
sorting block 112, #reads = 1114756 mem = 536878751 peak = 1120260096
[M::mem_process_seqs] Processed 749324 reads in 138.376 CPU sec, 4.386 real sec
[M::process] read 747052 sequences (100000033 bp) in 2.845 CPU sec, 2.926 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 301455, 27, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (126, 218, 538)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1362)
[M::mem_pestat] mean and std.dev: (393.16, 394.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1970)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 160, 218)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 418)
[M::mem_pestat] mean and std.dev: (173.28, 72.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 518)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 362, 1473)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4031)
[M::mem_pestat] mean and std.dev: (699.48, 678.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5310)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 330, 1332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3620)
[M::mem_pestat] mean and std.dev: (698.28, 725.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4764)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 113, #reads = 1113179 mem = 536879168 peak = 1120260096
[M::process] read 747384 sequences (100000185 bp) in 3.119 CPU sec, 3.326 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (22, 300783, 20, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (119, 235, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 854)
[M::mem_pestat] mean and std.dev: (228.84, 152.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1099)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (119, 161, 219)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 419)
[M::mem_pestat] mean and std.dev: (174.17, 72.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 519)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 461, 1390)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3866)
[M::mem_pestat] mean and std.dev: (553.18, 677.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5104)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 250, 838)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2210)
[M::mem_pestat] mean and std.dev: (333.16, 318.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2896)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 748476 reads in 202.958 CPU sec, 6.490 real sec
[M::process] read 746964 sequences (100000294 bp) in 2.299 CPU sec, 2.308 real sec...
[M::mem_process_seqs] Processed 747052 reads in 142.661 CPU sec, 4.563 real sec
sorting block 114, #reads = 1108591 mem = 536879266 peak = 1120260096
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 300455, 30, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 201, 834)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2170)
[M::mem_pestat] mean and std.dev: (393.47, 348.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2838)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (119, 161, 218)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 416)
[M::mem_pestat] mean and std.dev: (173.55, 72.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 515)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (103, 503, 1271)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3607)
[M::mem_pestat] mean and std.dev: (498.96, 539.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4775)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 371, 833)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2119)
[M::mem_pestat] mean and std.dev: (420.94, 294.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2762)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 747020 sequences (100000179 bp) in 2.843 CPU sec, 3.017 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 300230, 20, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 217, 1043)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2807)
[M::mem_pestat] mean and std.dev: (586.42, 663.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3689)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (119, 161, 219)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 419)
[M::mem_pestat] mean and std.dev: (174.23, 72.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 519)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 757, 1364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3790)
[M::mem_pestat] mean and std.dev: (939.00, 961.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5003)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 268, 765)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1939)
[M::mem_pestat] mean and std.dev: (405.17, 343.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2526)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 746704 sequences (100000105 bp) in 2.190 CPU sec, 2.193 real sec...
[M::mem_process_seqs] Processed 747384 reads in 193.132 CPU sec, 6.196 real sec
sorting block 115, #reads = 1111163 mem = 536879619 peak = 1120260096
[M::mem_process_seqs] Processed 746964 reads in 127.657 CPU sec, 4.030 real sec
sorting block 116, #reads = 1111411 mem = 536879237 peak = 1120260096
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 300838, 18, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (281, 486, 1103)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2747)
[M::mem_pestat] mean and std.dev: (559.38, 448.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3569)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (119, 162, 220)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 422)
[M::mem_pestat] mean and std.dev: (174.57, 73.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 523)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 486, 657)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1567)
[M::mem_pestat] mean and std.dev: (376.62, 273.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2022)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 257, 603)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1411)
[M::mem_pestat] mean and std.dev: (302.21, 218.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1815)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 746904 sequences (100000051 bp) in 2.439 CPU sec, 2.499 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 300684, 27, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 390, 915)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2337)
[M::mem_pestat] mean and std.dev: (533.90, 468.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3048)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (119, 162, 218)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 416)
[M::mem_pestat] mean and std.dev: (173.77, 71.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 515)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 232, 1115)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3043)
[M::mem_pestat] mean and std.dev: (439.70, 600.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4007)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 339, 994)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2584)
[M::mem_pestat] mean and std.dev: (603.03, 570.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3379)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 746460 sequences (100000257 bp) in 2.270 CPU sec, 2.278 real sec...
[M::mem_process_seqs] Processed 747020 reads in 184.431 CPU sec, 5.900 real sec
[M::mem_process_seqs] Processed 746704 reads in 123.921 CPU sec, 4.079 real sec
sorting block 117, #reads = 1111170 mem = 536883471 peak = 1120260096
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 300699, 21, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 311, 717)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1761)
[M::mem_pestat] mean and std.dev: (377.57, 331.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2283)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (119, 161, 219)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 419)
[M::mem_pestat] mean and std.dev: (174.22, 72.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 519)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (63, 188, 536)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1482)
[M::mem_pestat] mean and std.dev: (266.74, 344.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1955)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (275, 391, 919)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2207)
[M::mem_pestat] mean and std.dev: (487.95, 367.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2851)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 746514 sequences (100000142 bp) in 2.714 CPU sec, 2.771 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 300478, 33, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 253, 635)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1577)
[M::mem_pestat] mean and std.dev: (317.93, 198.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2048)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (119, 162, 219)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 419)
[M::mem_pestat] mean and std.dev: (174.53, 72.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 519)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (232, 627, 2031)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5629)
[M::mem_pestat] mean and std.dev: (1088.09, 1185.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7428)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 255, 642)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1512)
[M::mem_pestat] mean and std.dev: (334.56, 300.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1947)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 747320 sequences (100000056 bp) in 2.240 CPU sec, 2.239 real sec...
[M::mem_process_seqs] Processed 746904 reads in 180.706 CPU sec, 5.856 real sec
[M::mem_process_seqs] Processed 746460 reads in 124.906 CPU sec, 4.094 real sec
sorting block 118, #reads = 1111929 mem = 536878731 peak = 1120260096
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 301124, 35, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 399, 1985)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5633)
[M::mem_pestat] mean and std.dev: (1161.53, 1540.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7457)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (119, 162, 219)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 419)
[M::mem_pestat] mean and std.dev: (174.14, 72.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 519)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 571, 851)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2179)
[M::mem_pestat] mean and std.dev: (569.70, 440.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2843)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 207, 652)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1636)
[M::mem_pestat] mean and std.dev: (331.63, 254.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2128)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 747208 sequences (100000289 bp) in 2.767 CPU sec, 2.843 real sec...
[M::process] read 83018 sequences (11058661 bp) in 0.480 CPU sec, 0.475 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 301607, 31, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 277, 924)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2416)
[M::mem_pestat] mean and std.dev: (452.68, 496.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3162)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (119, 161, 219)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 419)
[M::mem_pestat] mean and std.dev: (174.10, 72.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 519)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (325, 969, 1814)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4792)
[M::mem_pestat] mean and std.dev: (1098.07, 1021.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6281)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 271, 659)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1575)
[M::mem_pestat] mean and std.dev: (397.45, 315.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2033)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 746514 reads in 177.826 CPU sec, 5.816 real sec
sorting block 119, #reads = 1111885 mem = 536878805 peak = 1120260096
[M::mem_process_seqs] Processed 747320 reads in 123.031 CPU sec, 4.110 real sec
sorting block 120, #reads = 1112316 mem = 536884401 peak = 1120260096
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 301224, 27, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (134, 253, 892)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2408)
[M::mem_pestat] mean and std.dev: (422.32, 537.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3166)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (119, 161, 219)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 419)
[M::mem_pestat] mean and std.dev: (173.86, 72.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 519)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 509, 921)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2449)
[M::mem_pestat] mean and std.dev: (586.24, 529.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3213)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 386, 1871)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5189)
[M::mem_pestat] mean and std.dev: (892.15, 1115.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6848)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (2, 33301, 8, 3)
[M::mem_pestat] skip orientation FF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 159, 214)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 408)
[M::mem_pestat] mean and std.dev: (170.45, 70.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 505)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] skip orientation RR as there are not enough pairs
[M::mem_process_seqs] Processed 83018 reads in 31.919 CPU sec, 1.029 real sec
[M::mem_process_seqs] Processed 747208 reads in 107.902 CPU sec, 3.763 real sec
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000c06f2
  features: 1f8bfbff fffab20b
  extended: f1bf07ab 1a407f7e
  amd bits: 2c100800 00000121
     brand: Intel(R) Xeon(R) Platinum 8559C
threads: 31
algo: bwa-mem
license: sentieon:klib=31
reads: 134578824
overall: 70095663104 mem 22434.327 user 416.680 sys 776.146 real
sorting block 121, #reads = 913017 mem = 441225777 peak = 1120260096
[main] Version: 0.7.17-r1188
[main] CMD: /opt/conda/share/sentieon-202308.03-3/libexec/bwa mem -K 100000000 -Y -R @RG\tID:A23MHWWLT4.659_dm4-T1-TDNA-1_A23MHWWLT4_1.L001\tPU:L001\tSM:659_dm4-T1-TDNA-1_A23MHWWLT4_1\tLB:659_dm4-T1-TDNA-1_A23MHWWLT4_1\tDS:s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta\tPL:ILLUMINA -t 31 ./BWAIndex/Homo_sapiens_assembly38.fasta.64 659_dm4-T1-TDNA-1_A23MHWWLT4_1_R1.fastq.gz 659_dm4-T1-TDNA-1_A23MHWWLT4_1_R2.fastq.gz
[main] Real time: 776.199 sec; CPU: 22851.027 sec
uniq header count 1
merging 122 blocks
sw version: sentieon-genomics-202308.03
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000c06f2
  features: 1f8bfbff fffab20b
  extended: f1bf07ab 1a407f7e
  amd bits: 2c100800 00000121
     brand: Intel(R) Xeon(R) Platinum 8559C
threads: 31 max 192
algo: util-sort
license: sentieon:util=1
output file size: 6970630365
output reads: 135750881
bam_mem_sort: 122 calls 79.385 user 1.376 sys 84.189 real
bam_write: 122 calls 83.368 user 6.065 sys 196.372 real
execute: 1 calls 29.995 user 1.319 sys 819.760 real
merge_files: 1 calls 29.988 user 1.272 sys 43.079 real
parse_chunk: 1950 calls 116.363 user 32.162 sys 201.856 real
read_chunk: 5295 calls 66.250 user 31.914 sys 712.691 real
sort_block: 1 calls 51.602 user 31.333 sys 693.989 real
write_chunk: 3343 calls 29.585 user 1.045 sys 42.174 real
overall: 3717046272 mem 1821.077 user 86.226 sys 819.782 real
ls: cannot access '*.cram': No such file or directory