cmdline: /opt/conda/share/sentieon-202308.03-3/libexec/util sort -r Homo_sapiens_assembly38.fasta -t 31 -o 1136_3WJ-T1-TDNA-1_A23MHWWLT4_1.bam --sam2bam -
This software is licensed to bgold@natera.com by Sentieon Inc.
This software is licensed to bgold@natera.com by Sentieon Inc.
version: sentieon-genomics-202308.03
[M::bwa_idx_load_from_disk] read 3171 ALT contigs
[M::main_mem] bwa index loaded in 1411.158 CPU sec, 50.810 real sec
[M::process] read 711848 sequences (100000104 bp) in 1.279 CPU sec, 1.287 real sec...
[M::process] read 710084 sequences (100000224 bp) in 1.565 CPU sec, 1.690 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 283096, 32, 79)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 611, 1300)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3490)
[M::mem_pestat] mean and std.dev: (903.06, 864.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4585)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (143, 209, 303)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 623)
[M::mem_pestat] mean and std.dev: (232.84, 114.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 783)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (548, 955, 2422)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6170)
[M::mem_pestat] mean and std.dev: (1304.17, 1270.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8044)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 377, 1077)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2873)
[M::mem_pestat] mean and std.dev: (571.19, 608.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3771)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 708564 sequences (100000056 bp) in 1.538 CPU sec, 1.536 real sec...
[M::process] read 707426 sequences (100000065 bp) in 1.599 CPU sec, 1.604 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 282396, 43, 77)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 530, 1569)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4357)
[M::mem_pestat] mean and std.dev: (772.00, 831.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5751)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 212, 308)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 634)
[M::mem_pestat] mean and std.dev: (236.03, 116.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 797)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 608, 2111)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5965)
[M::mem_pestat] mean and std.dev: (1059.20, 1309.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7892)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 370, 825)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1987)
[M::mem_pestat] mean and std.dev: (543.23, 412.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2568)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 711848 reads in 197.302 CPU sec, 6.388 real sec
[M::mem_process_seqs] Processed 710084 reads in 139.320 CPU sec, 4.477 real sec
sorting block 0, #reads = 1072355 mem = 536881225 peak = 593674240
[M::process] read 706472 sequences (100000174 bp) in 2.293 CPU sec, 2.416 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (94, 281996, 43, 84)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 272, 1010)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2732)
[M::mem_pestat] mean and std.dev: (525.95, 584.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3593)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 215, 313)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 645)
[M::mem_pestat] mean and std.dev: (239.05, 118.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 811)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 670, 1127)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2983)
[M::mem_pestat] mean and std.dev: (787.41, 713.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3911)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 543, 888)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2224)
[M::mem_pestat] mean and std.dev: (607.17, 494.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2892)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705728 sequences (100000280 bp) in 1.629 CPU sec, 1.628 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (103, 281358, 60, 99)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (264, 345, 838)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1986)
[M::mem_pestat] mean and std.dev: (428.35, 326.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2560)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 218, 315)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 649)
[M::mem_pestat] mean and std.dev: (241.70, 119.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 816)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (284, 584, 1142)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2858)
[M::mem_pestat] mean and std.dev: (661.96, 558.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3716)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (246, 498, 1673)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4527)
[M::mem_pestat] mean and std.dev: (1070.99, 1213.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5954)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 708564 reads in 183.637 CPU sec, 5.904 real sec
[M::mem_process_seqs] Processed 707426 reads in 126.942 CPU sec, 4.123 real sec
sorting block 1, #reads = 1071717 mem = 536879111 peak = 749387776
[M::process] read 705258 sequences (100000191 bp) in 2.259 CPU sec, 2.438 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (85, 281163, 44, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (229, 512, 1186)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3100)
[M::mem_pestat] mean and std.dev: (718.64, 645.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4057)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 219, 319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 659)
[M::mem_pestat] mean and std.dev: (243.79, 120.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 829)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 425, 685)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1737)
[M::mem_pestat] mean and std.dev: (430.50, 363.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2263)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 409, 1497)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4059)
[M::mem_pestat] mean and std.dev: (672.58, 598.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5340)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705524 sequences (100000214 bp) in 1.547 CPU sec, 1.563 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (79, 280372, 24, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (235, 348, 884)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2182)
[M::mem_pestat] mean and std.dev: (549.56, 484.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2831)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 222, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 666)
[M::mem_pestat] mean and std.dev: (245.74, 121.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 838)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 699, 2219)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6289)
[M::mem_pestat] mean and std.dev: (1172.39, 1520.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8324)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (236, 334, 981)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2471)
[M::mem_pestat] mean and std.dev: (460.65, 389.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3216)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 280916, 45, 84)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 338, 540)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1262)
[M::mem_pestat] mean and std.dev: (341.13, 220.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1623)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 222, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 664)
[M::mem_pestat] mean and std.dev: (245.90, 121.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 835)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (482, 1110, 2034)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5138)
[M::mem_pestat] mean and std.dev: (1327.00, 978.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6690)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (235, 510, 1199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3127)
[M::mem_pestat] mean and std.dev: (572.76, 571.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4091)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 706472 reads in 255.984 CPU sec, 8.278 real sec
sorting block 2, #reads = 1070747 mem = 536879047 peak = 749387776
[M::mem_process_seqs] Processed 705728 reads in 199.472 CPU sec, 6.505 real sec
[M::mem_process_seqs] Processed 705258 reads in 227.354 CPU sec, 7.430 real sec
sorting block 3, #reads = 1069568 mem = 536877120 peak = 763785216
[M::process] read 705180 sequences (100000187 bp) in 2.579 CPU sec, 2.719 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 280899, 56, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (249, 677, 1005)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2517)
[M::mem_pestat] mean and std.dev: (699.49, 609.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3273)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 222, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 664)
[M::mem_pestat] mean and std.dev: (245.90, 121.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 835)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (501, 1325, 2236)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5706)
[M::mem_pestat] mean and std.dev: (1545.37, 1442.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7441)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 377, 778)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1888)
[M::mem_pestat] mean and std.dev: (495.97, 441.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2443)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704478 sequences (100000038 bp) in 2.448 CPU sec, 2.600 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (79, 280597, 39, 75)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 423, 1081)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2837)
[M::mem_pestat] mean and std.dev: (548.26, 528.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3715)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 222, 320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 658)
[M::mem_pestat] mean and std.dev: (245.30, 120.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 827)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (382, 899, 1982)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5182)
[M::mem_pestat] mean and std.dev: (1309.62, 1281.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6782)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (267, 444, 979)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2403)
[M::mem_pestat] mean and std.dev: (494.52, 407.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3115)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 705524 reads in 188.347 CPU sec, 6.002 real sec
[M::mem_process_seqs] Processed 705180 reads in 130.273 CPU sec, 4.119 real sec
[M::process] read 704162 sequences (100000021 bp) in 1.888 CPU sec, 1.975 real sec...
sorting block 4, #reads = 1070117 mem = 536879710 peak = 763785216
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (77, 280459, 33, 76)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 309, 1219)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3273)
[M::mem_pestat] mean and std.dev: (562.66, 580.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4300)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 224, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 668)
[M::mem_pestat] mean and std.dev: (247.73, 121.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 840)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 312, 1986)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5620)
[M::mem_pestat] mean and std.dev: (962.23, 1132.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7437)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 338, 1005)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2569)
[M::mem_pestat] mean and std.dev: (605.76, 588.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3351)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 5, #reads = 1069835 mem = 536878980 peak = 787812352
[M::process] read 703944 sequences (100000138 bp) in 2.184 CPU sec, 2.428 real sec...
[M::process] read 703812 sequences (100000035 bp) in 1.635 CPU sec, 1.638 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 280014, 62, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 315, 977)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2555)
[M::mem_pestat] mean and std.dev: (505.68, 481.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3344)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 224, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 662)
[M::mem_pestat] mean and std.dev: (246.84, 120.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 832)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 388, 1149)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3097)
[M::mem_pestat] mean and std.dev: (597.98, 601.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4071)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (258, 429, 875)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2109)
[M::mem_pestat] mean and std.dev: (598.71, 431.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2726)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704478 reads in 184.673 CPU sec, 5.906 real sec
[M::mem_process_seqs] Processed 704162 reads in 133.372 CPU sec, 4.266 real sec
sorting block 6, #reads = 1068608 mem = 536880412 peak = 787812352
[M::process] read 704468 sequences (100000266 bp) in 2.473 CPU sec, 2.562 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 280143, 54, 85)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 377, 1273)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3459)
[M::mem_pestat] mean and std.dev: (625.73, 645.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4552)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 224, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 660)
[M::mem_pestat] mean and std.dev: (246.75, 120.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 829)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (514, 1189, 1989)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4939)
[M::mem_pestat] mean and std.dev: (1287.04, 992.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6414)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (269, 375, 1257)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3233)
[M::mem_pestat] mean and std.dev: (672.64, 602.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4221)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704344 sequences (100000291 bp) in 2.050 CPU sec, 2.057 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (82, 280549, 42, 100)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (262, 727, 1757)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4747)
[M::mem_pestat] mean and std.dev: (1110.37, 1194.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6242)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 224, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 659)
[M::mem_pestat] mean and std.dev: (246.28, 119.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 828)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (294, 805, 1620)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4272)
[M::mem_pestat] mean and std.dev: (869.33, 756.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5598)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 468, 1191)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3147)
[M::mem_pestat] mean and std.dev: (613.81, 547.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4125)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703812 reads in 189.131 CPU sec, 5.995 real sec
[M::mem_process_seqs] Processed 703944 reads in 211.508 CPU sec, 6.722 real sec
sorting block 7, #reads = 1067405 mem = 536879551 peak = 787812352
[M::process] read 704654 sequences (100000042 bp) in 2.405 CPU sec, 2.460 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (73, 280207, 43, 80)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (237, 440, 1045)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2661)
[M::mem_pestat] mean and std.dev: (570.02, 530.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3469)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 222, 319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 653)
[M::mem_pestat] mean and std.dev: (244.95, 119.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 820)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (238, 712, 1896)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5212)
[M::mem_pestat] mean and std.dev: (905.58, 952.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6870)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 330, 830)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2088)
[M::mem_pestat] mean and std.dev: (439.51, 374.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2717)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704482 sequences (100000256 bp) in 1.510 CPU sec, 1.510 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (98, 280407, 39, 82)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 342, 728)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1740)
[M::mem_pestat] mean and std.dev: (404.84, 301.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2246)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 222, 319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 655)
[M::mem_pestat] mean and std.dev: (244.65, 119.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 823)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (271, 745, 1307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3379)
[M::mem_pestat] mean and std.dev: (911.45, 857.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4415)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 489, 1017)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2601)
[M::mem_pestat] mean and std.dev: (621.99, 539.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3393)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704468 reads in 165.073 CPU sec, 5.229 real sec
sorting block 8, #reads = 1067293 mem = 536884173 peak = 787812352
[M::mem_process_seqs] Processed 704344 reads in 191.228 CPU sec, 6.077 real sec
[M::process] read 708976 sequences (100000058 bp) in 2.559 CPU sec, 2.630 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (91, 280628, 32, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 284, 873)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2251)
[M::mem_pestat] mean and std.dev: (459.10, 426.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2940)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 223, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 659)
[M::mem_pestat] mean and std.dev: (245.81, 120.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 828)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (264, 540, 1322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3438)
[M::mem_pestat] mean and std.dev: (680.87, 705.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4496)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (248, 354, 1210)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3134)
[M::mem_pestat] mean and std.dev: (477.53, 412.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4096)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 709978 sequences (100000072 bp) in 2.083 CPU sec, 2.086 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (79, 280311, 61, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 327, 1055)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2805)
[M::mem_pestat] mean and std.dev: (642.99, 670.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3680)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 223, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 668)
[M::mem_pestat] mean and std.dev: (247.40, 122.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 840)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (271, 647, 930)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2248)
[M::mem_pestat] mean and std.dev: (556.41, 373.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2907)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (238, 398, 654)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1486)
[M::mem_pestat] mean and std.dev: (436.96, 286.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1902)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704654 reads in 216.011 CPU sec, 6.933 real sec
sorting block 9, #reads = 1067098 mem = 536881206 peak = 836255744
[M::mem_process_seqs] Processed 704482 reads in 249.346 CPU sec, 8.121 real sec
sorting block 10, #reads = 1066497 mem = 536882435 peak = 995225600
[M::process] read 708474 sequences (100000080 bp) in 2.715 CPU sec, 2.813 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (76, 282118, 42, 78)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 378, 1082)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2848)
[M::mem_pestat] mean and std.dev: (587.03, 519.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3731)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 214, 310)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 638)
[M::mem_pestat] mean and std.dev: (237.65, 117.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 802)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 643, 1551)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4261)
[M::mem_pestat] mean and std.dev: (826.89, 773.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5616)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 404, 1040)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2730)
[M::mem_pestat] mean and std.dev: (622.43, 535.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3575)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 707536 sequences (100000216 bp) in 1.953 CPU sec, 1.958 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (79, 282220, 57, 79)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 278, 627)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1503)
[M::mem_pestat] mean and std.dev: (334.91, 261.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1941)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 216, 311)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 639)
[M::mem_pestat] mean and std.dev: (238.20, 116.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 803)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (387, 975, 2111)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5559)
[M::mem_pestat] mean and std.dev: (1492.54, 1553.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7707)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 458, 897)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2253)
[M::mem_pestat] mean and std.dev: (581.77, 441.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2931)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (73, 282910, 44, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 238, 1078)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2868)
[M::mem_pestat] mean and std.dev: (521.22, 566.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3763)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 213, 309)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 637)
[M::mem_pestat] mean and std.dev: (236.11, 116.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 801)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (741, 1251, 1855)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4083)
[M::mem_pestat] mean and std.dev: (1111.61, 743.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5197)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 449, 1003)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2571)
[M::mem_pestat] mean and std.dev: (528.25, 418.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3355)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 708976 reads in 309.675 CPU sec, 10.032 real sec
[M::mem_process_seqs] Processed 708474 reads in 235.073 CPU sec, 7.588 real sec
sorting block 11, #reads = 1069296 mem = 536877457 peak = 995225600
[M::mem_process_seqs] Processed 709978 reads in 265.994 CPU sec, 8.608 real sec
[M::process] read 707170 sequences (100000058 bp) in 2.881 CPU sec, 3.197 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (86, 281925, 51, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 436, 853)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2111)
[M::mem_pestat] mean and std.dev: (548.84, 427.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2740)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 217, 315)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 649)
[M::mem_pestat] mean and std.dev: (240.70, 118.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 816)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (337, 592, 1321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3289)
[M::mem_pestat] mean and std.dev: (787.98, 757.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4273)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 334, 616)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1450)
[M::mem_pestat] mean and std.dev: (431.38, 280.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1867)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 12, #reads = 1074238 mem = 536879726 peak = 995225600
[M::process] read 706496 sequences (100000099 bp) in 2.574 CPU sec, 2.678 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (74, 282094, 26, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 361, 1356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3686)
[M::mem_pestat] mean and std.dev: (704.43, 777.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4851)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 220, 318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 656)
[M::mem_pestat] mean and std.dev: (243.24, 119.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 825)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (262, 590, 1212)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3112)
[M::mem_pestat] mean and std.dev: (732.79, 777.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4062)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 307, 925)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2335)
[M::mem_pestat] mean and std.dev: (490.56, 407.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3040)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 707536 reads in 215.012 CPU sec, 6.905 real sec
[M::process] read 705676 sequences (100000079 bp) in 2.216 CPU sec, 2.261 real sec...
[M::mem_process_seqs] Processed 707170 reads in 155.979 CPU sec, 5.145 real sec
sorting block 13, #reads = 1074253 mem = 536878119 peak = 995225600
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 281237, 52, 85)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 294, 617)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1449)
[M::mem_pestat] mean and std.dev: (352.69, 270.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1865)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 220, 319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 659)
[M::mem_pestat] mean and std.dev: (243.87, 120.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 829)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 580, 1793)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4977)
[M::mem_pestat] mean and std.dev: (1000.26, 1119.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6569)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 333, 736)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1782)
[M::mem_pestat] mean and std.dev: (428.22, 321.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2305)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705394 sequences (100000131 bp) in 2.600 CPU sec, 2.875 real sec...
[M::process] read 705100 sequences (100000267 bp) in 2.190 CPU sec, 2.193 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (115, 281034, 44, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 295, 570)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1262)
[M::mem_pestat] mean and std.dev: (338.21, 193.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1608)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 222, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 661)
[M::mem_pestat] mean and std.dev: (245.25, 120.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 831)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 699, 1415)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3813)
[M::mem_pestat] mean and std.dev: (853.35, 882.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5012)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 338, 836)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2162)
[M::mem_pestat] mean and std.dev: (457.31, 441.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2825)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 706496 reads in 216.955 CPU sec, 7.141 real sec
sorting block 14, #reads = 1071886 mem = 536880982 peak = 995225600
[M::mem_process_seqs] Processed 705676 reads in 156.655 CPU sec, 5.009 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 281263, 38, 90)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 361, 822)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2070)
[M::mem_pestat] mean and std.dev: (471.40, 390.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2694)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 223, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 670)
[M::mem_pestat] mean and std.dev: (247.08, 122.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 843)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (248, 518, 985)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2459)
[M::mem_pestat] mean and std.dev: (571.39, 539.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3196)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (297, 646, 1012)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2442)
[M::mem_pestat] mean and std.dev: (698.86, 548.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3157)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704466 sequences (100000037 bp) in 2.744 CPU sec, 2.949 real sec...
[M::process] read 704882 sequences (100000186 bp) in 2.239 CPU sec, 2.248 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (74, 280720, 48, 83)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 338, 603)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1393)
[M::mem_pestat] mean and std.dev: (378.00, 249.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1788)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 224, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 670)
[M::mem_pestat] mean and std.dev: (247.43, 122.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 843)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (251, 622, 941)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2321)
[M::mem_pestat] mean and std.dev: (509.29, 433.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3011)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (231, 381, 1186)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3096)
[M::mem_pestat] mean and std.dev: (566.04, 601.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4051)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 705394 reads in 221.258 CPU sec, 7.217 real sec
sorting block 15, #reads = 1071324 mem = 536879756 peak = 995225600
[M::mem_process_seqs] Processed 705100 reads in 157.757 CPU sec, 5.185 real sec
sorting block 16, #reads = 1070206 mem = 536882760 peak = 1004163072
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (90, 280716, 49, 88)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (279, 644, 1093)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2721)
[M::mem_pestat] mean and std.dev: (671.47, 493.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3535)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 224, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 662)
[M::mem_pestat] mean and std.dev: (246.63, 120.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 832)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (398, 767, 1600)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4004)
[M::mem_pestat] mean and std.dev: (1031.24, 841.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5206)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 427, 961)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2479)
[M::mem_pestat] mean and std.dev: (512.34, 417.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3238)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703964 sequences (100000212 bp) in 2.870 CPU sec, 3.039 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (87, 281031, 65, 94)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 286, 984)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2550)
[M::mem_pestat] mean and std.dev: (519.63, 517.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3333)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 223, 323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 667)
[M::mem_pestat] mean and std.dev: (246.85, 121.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 839)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (135, 581, 1272)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3546)
[M::mem_pestat] mean and std.dev: (670.82, 654.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4683)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 388, 965)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2511)
[M::mem_pestat] mean and std.dev: (537.44, 502.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3284)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704662 sequences (100000223 bp) in 2.360 CPU sec, 2.367 real sec...
[M::mem_process_seqs] Processed 704466 reads in 219.065 CPU sec, 7.057 real sec
[M::mem_process_seqs] Processed 704882 reads in 166.127 CPU sec, 5.349 real sec
sorting block 17, #reads = 1070481 mem = 536877894 peak = 1004163072
[M::process] read 704774 sequences (100000106 bp) in 2.730 CPU sec, 2.923 real sec...
[M::process] read 704690 sequences (100000017 bp) in 2.326 CPU sec, 2.328 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (76, 280691, 47, 79)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 388, 1015)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2675)
[M::mem_pestat] mean and std.dev: (476.55, 456.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3505)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 222, 320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 658)
[M::mem_pestat] mean and std.dev: (245.25, 119.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 827)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 742, 1360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3642)
[M::mem_pestat] mean and std.dev: (648.95, 555.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4783)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (283, 707, 1472)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3850)
[M::mem_pestat] mean and std.dev: (896.80, 794.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5039)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704662 reads in 130.666 CPU sec, 4.144 real sec
sorting block 18, #reads = 1070098 mem = 536884959 peak = 1004163072
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (97, 280115, 43, 82)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (250, 660, 1375)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3625)
[M::mem_pestat] mean and std.dev: (843.30, 756.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4750)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 225, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 669)
[M::mem_pestat] mean and std.dev: (248.00, 121.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 841)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 651, 1046)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2756)
[M::mem_pestat] mean and std.dev: (714.17, 619.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3611)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (253, 459, 1121)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2857)
[M::mem_pestat] mean and std.dev: (606.17, 506.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3725)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 280596, 40, 99)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 402, 693)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1757)
[M::mem_pestat] mean and std.dev: (367.27, 252.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2289)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 222, 320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 658)
[M::mem_pestat] mean and std.dev: (245.26, 120.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 827)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (362, 715, 2305)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6191)
[M::mem_pestat] mean and std.dev: (1261.64, 1358.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8134)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (259, 449, 844)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2014)
[M::mem_pestat] mean and std.dev: (539.35, 391.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2599)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703964 reads in 352.488 CPU sec, 11.272 real sec
[M::process] read 704348 sequences (100000010 bp) in 2.293 CPU sec, 2.311 real sec...
[M::mem_process_seqs] Processed 704774 reads in 195.107 CPU sec, 6.295 real sec
sorting block 19, #reads = 1068145 mem = 536885453 peak = 1004163072
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 280594, 47, 72)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (240, 314, 919)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2277)
[M::mem_pestat] mean and std.dev: (456.46, 392.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2956)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 222, 320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 658)
[M::mem_pestat] mean and std.dev: (245.13, 119.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 827)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (539, 927, 2947)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7763)
[M::mem_pestat] mean and std.dev: (1731.68, 1630.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10171)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 258, 436)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 916)
[M::mem_pestat] mean and std.dev: (286.48, 170.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1156)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704988 sequences (100000192 bp) in 2.882 CPU sec, 3.015 real sec...
[M::process] read 704696 sequences (100000097 bp) in 1.860 CPU sec, 1.860 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (73, 280690, 52, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 381, 871)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2223)
[M::mem_pestat] mean and std.dev: (510.56, 452.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2899)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 223, 320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 656)
[M::mem_pestat] mean and std.dev: (245.66, 119.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 824)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (748, 1308, 2268)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5308)
[M::mem_pestat] mean and std.dev: (1317.74, 906.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6828)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (253, 523, 1406)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3712)
[M::mem_pestat] mean and std.dev: (790.92, 740.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4865)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704690 reads in 222.322 CPU sec, 7.415 real sec
sorting block 20, #reads = 1068147 mem = 536879288 peak = 1004163072
[M::mem_process_seqs] Processed 704348 reads in 155.274 CPU sec, 4.959 real sec
[M::process] read 710702 sequences (100000004 bp) in 2.735 CPU sec, 2.818 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 279947, 44, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 539, 1124)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2994)
[M::mem_pestat] mean and std.dev: (647.18, 556.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3929)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 222, 323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 667)
[M::mem_pestat] mean and std.dev: (246.77, 122.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 839)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (227, 491, 1146)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2984)
[M::mem_pestat] mean and std.dev: (727.30, 701.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3903)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 632, 1518)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4178)
[M::mem_pestat] mean and std.dev: (841.09, 839.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5508)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 708954 sequences (100000138 bp) in 1.940 CPU sec, 1.937 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 280043, 46, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (262, 500, 1288)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3340)
[M::mem_pestat] mean and std.dev: (836.69, 829.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4366)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 222, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 661)
[M::mem_pestat] mean and std.dev: (245.92, 121.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 831)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (403, 701, 1545)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3829)
[M::mem_pestat] mean and std.dev: (851.05, 688.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4971)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 381, 1040)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2690)
[M::mem_pestat] mean and std.dev: (610.88, 630.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3515)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704696 reads in 194.851 CPU sec, 6.161 real sec
sorting block 21, #reads = 1067513 mem = 536877429 peak = 1004163072
[M::mem_process_seqs] Processed 704988 reads in 229.160 CPU sec, 7.275 real sec
sorting block 22, #reads = 1065272 mem = 536877374 peak = 1023836160
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 282159, 37, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 409, 904)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2342)
[M::mem_pestat] mean and std.dev: (531.88, 467.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3061)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 215, 311)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 639)
[M::mem_pestat] mean and std.dev: (237.85, 116.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 803)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (392, 925, 1611)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4049)
[M::mem_pestat] mean and std.dev: (976.94, 779.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5268)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 313, 1185)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3119)
[M::mem_pestat] mean and std.dev: (808.56, 878.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4321)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 707782 sequences (100000169 bp) in 2.915 CPU sec, 3.078 real sec...
[M::process] read 707170 sequences (100000036 bp) in 2.086 CPU sec, 2.088 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 282574, 47, 90)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 292, 921)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2403)
[M::mem_pestat] mean and std.dev: (472.51, 471.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3144)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 211, 305)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 625)
[M::mem_pestat] mean and std.dev: (233.66, 114.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 785)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (335, 887, 1221)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2993)
[M::mem_pestat] mean and std.dev: (746.19, 594.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3879)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 426, 827)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2107)
[M::mem_pestat] mean and std.dev: (565.05, 524.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2747)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 708954 reads in 197.875 CPU sec, 6.269 real sec
[M::mem_process_seqs] Processed 710702 reads in 230.103 CPU sec, 7.317 real sec
sorting block 23, #reads = 1071198 mem = 536879483 peak = 1023836160
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 282102, 45, 76)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 478, 1041)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2683)
[M::mem_pestat] mean and std.dev: (603.27, 467.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3504)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 217, 313)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 643)
[M::mem_pestat] mean and std.dev: (239.85, 117.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 808)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (389, 700, 1347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3263)
[M::mem_pestat] mean and std.dev: (663.68, 451.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4221)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 374, 772)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2014)
[M::mem_pestat] mean and std.dev: (411.10, 346.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2635)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706582 sequences (100000007 bp) in 3.386 CPU sec, 3.570 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 281529, 39, 79)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 264, 612)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1468)
[M::mem_pestat] mean and std.dev: (424.96, 343.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1896)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 219, 317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 653)
[M::mem_pestat] mean and std.dev: (242.40, 119.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 821)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (567, 1032, 2087)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5127)
[M::mem_pestat] mean and std.dev: (1243.77, 949.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6647)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (257, 467, 1354)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3548)
[M::mem_pestat] mean and std.dev: (858.43, 840.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4645)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706134 sequences (100000241 bp) in 2.190 CPU sec, 2.188 real sec...
[M::mem_process_seqs] Processed 707782 reads in 197.315 CPU sec, 6.232 real sec
sorting block 24, #reads = 1072366 mem = 536879343 peak = 1023836160
[M::mem_process_seqs] Processed 707170 reads in 226.750 CPU sec, 7.189 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 281526, 41, 93)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 352, 725)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1827)
[M::mem_pestat] mean and std.dev: (435.77, 372.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2378)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 221, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 666)
[M::mem_pestat] mean and std.dev: (245.48, 121.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 838)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 628, 1703)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4699)
[M::mem_pestat] mean and std.dev: (872.59, 968.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6197)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 366, 1177)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3151)
[M::mem_pestat] mean and std.dev: (670.42, 782.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4138)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705150 sequences (100000235 bp) in 3.759 CPU sec, 3.926 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (82, 281345, 45, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (238, 322, 1277)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3355)
[M::mem_pestat] mean and std.dev: (762.72, 851.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4394)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 220, 319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 659)
[M::mem_pestat] mean and std.dev: (243.47, 119.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 829)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 610, 1148)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3134)
[M::mem_pestat] mean and std.dev: (668.32, 678.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4127)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (283, 576, 1268)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3238)
[M::mem_pestat] mean and std.dev: (800.53, 744.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4223)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 706134 reads in 199.268 CPU sec, 6.281 real sec
sorting block 25, #reads = 1072120 mem = 536879268 peak = 1023836160
[M::process] read 704824 sequences (100000053 bp) in 2.509 CPU sec, 2.510 real sec...
[M::mem_process_seqs] Processed 706582 reads in 230.898 CPU sec, 7.311 real sec
sorting block 26, #reads = 1071136 mem = 536882052 peak = 1023836160
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (114, 280892, 53, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (236, 290, 473)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 947)
[M::mem_pestat] mean and std.dev: (316.41, 178.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1184)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 223, 323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 667)
[M::mem_pestat] mean and std.dev: (246.95, 121.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 839)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (320, 866, 1784)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4712)
[M::mem_pestat] mean and std.dev: (1014.18, 873.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6176)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 364, 835)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2061)
[M::mem_pestat] mean and std.dev: (497.00, 465.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2674)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704116 sequences (100000244 bp) in 2.680 CPU sec, 2.759 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (86, 280917, 31, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 587, 1234)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3262)
[M::mem_pestat] mean and std.dev: (697.11, 534.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4276)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::process] read 703606 sequences (100000139 bp) in 2.380 CPU sec, 2.383 real sec...
[M::mem_pestat] (25, 50, 75) percentile: (152, 225, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 671)
[M::mem_pestat] mean and std.dev: (248.08, 122.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 844)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (243, 800, 3485)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9969)
[M::mem_pestat] mean and std.dev: (1712.83, 1834.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13211)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 430, 884)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2234)
[M::mem_pestat] mean and std.dev: (557.34, 473.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2909)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 705150 reads in 199.712 CPU sec, 6.561 real sec
[M::mem_process_seqs] Processed 704824 reads in 145.720 CPU sec, 4.620 real sec
sorting block 27, #reads = 1069806 mem = 536878213 peak = 1023836160
[M::process] read 703830 sequences (100000145 bp) in 2.629 CPU sec, 2.712 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (85, 280983, 62, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 264, 844)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2158)
[M::mem_pestat] mean and std.dev: (442.44, 429.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2815)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 225, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 669)
[M::mem_pestat] mean and std.dev: (248.42, 122.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 841)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (125, 427, 945)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2585)
[M::mem_pestat] mean and std.dev: (572.95, 647.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3405)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (262, 593, 1408)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3700)
[M::mem_pestat] mean and std.dev: (825.32, 843.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4846)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703842 sequences (100000032 bp) in 2.210 CPU sec, 2.217 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (87, 280594, 47, 88)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (242, 426, 970)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2426)
[M::mem_pestat] mean and std.dev: (596.76, 483.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3154)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 226, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 669)
[M::mem_pestat] mean and std.dev: (248.58, 121.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 841)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (465, 842, 1724)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4242)
[M::mem_pestat] mean and std.dev: (939.36, 786.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5501)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (280, 690, 1213)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3079)
[M::mem_pestat] mean and std.dev: (771.83, 635.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4012)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704116 reads in 196.160 CPU sec, 6.200 real sec
sorting block 28, #reads = 1070027 mem = 536887475 peak = 1023836160
[M::mem_process_seqs] Processed 703606 reads in 226.270 CPU sec, 7.417 real sec
[M::process] read 704410 sequences (100000156 bp) in 2.761 CPU sec, 2.836 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (115, 280289, 55, 84)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 419, 916)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2306)
[M::mem_pestat] mean and std.dev: (574.36, 519.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3001)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 224, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 662)
[M::mem_pestat] mean and std.dev: (246.64, 120.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 832)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 402, 1161)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3077)
[M::mem_pestat] mean and std.dev: (701.06, 754.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4035)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 554, 1353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3635)
[M::mem_pestat] mean and std.dev: (797.03, 815.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4776)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704242 sequences (100000086 bp) in 2.175 CPU sec, 2.184 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (85, 279908, 43, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (297, 532, 1359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3483)
[M::mem_pestat] mean and std.dev: (791.88, 731.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4545)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 223, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 659)
[M::mem_pestat] mean and std.dev: (245.53, 119.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 828)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (559, 1093, 2433)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6181)
[M::mem_pestat] mean and std.dev: (1489.43, 1205.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8055)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (242, 390, 1785)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4871)
[M::mem_pestat] mean and std.dev: (764.42, 815.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6414)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703830 reads in 201.724 CPU sec, 6.616 real sec
sorting block 29, #reads = 1069857 mem = 536880651 peak = 1023836160
[M::mem_process_seqs] Processed 703842 reads in 233.952 CPU sec, 7.437 real sec
sorting block 30, #reads = 1068511 mem = 536878776 peak = 1053925376
[M::process] read 704336 sequences (100000171 bp) in 2.481 CPU sec, 2.537 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 280917, 47, 81)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 283, 599)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1427)
[M::mem_pestat] mean and std.dev: (330.00, 226.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1841)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 222, 319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 653)
[M::mem_pestat] mean and std.dev: (244.70, 119.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 820)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (97, 939, 1726)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4984)
[M::mem_pestat] mean and std.dev: (1107.11, 1159.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6613)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (259, 486, 1191)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3055)
[M::mem_pestat] mean and std.dev: (694.72, 659.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3987)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704478 sequences (100000170 bp) in 1.690 CPU sec, 1.689 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (78, 279945, 28, 76)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 259, 541)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1263)
[M::mem_pestat] mean and std.dev: (368.44, 291.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1624)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 223, 319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 653)
[M::mem_pestat] mean and std.dev: (244.77, 118.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 820)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (451, 1010, 1230)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2788)
[M::mem_pestat] mean and std.dev: (898.73, 665.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3567)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 406, 772)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1890)
[M::mem_pestat] mean and std.dev: (516.15, 397.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2449)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704410 reads in 207.229 CPU sec, 6.588 real sec
[M::mem_process_seqs] Processed 704242 reads in 239.130 CPU sec, 7.692 real sec
sorting block 31, #reads = 1066826 mem = 536877929 peak = 1053925376
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (73, 280483, 43, 106)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 423, 855)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2251)
[M::mem_pestat] mean and std.dev: (498.45, 484.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2949)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 222, 317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 647)
[M::mem_pestat] mean and std.dev: (243.55, 117.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 812)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 549, 1506)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4104)
[M::mem_pestat] mean and std.dev: (759.08, 867.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5403)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 299, 889)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2231)
[M::mem_pestat] mean and std.dev: (516.46, 462.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2902)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704380 sequences (100000008 bp) in 2.857 CPU sec, 2.914 real sec...
[M::process] read 704642 sequences (100000061 bp) in 2.370 CPU sec, 2.378 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (77, 280950, 40, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 397, 966)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2560)
[M::mem_pestat] mean and std.dev: (552.05, 476.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3357)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 222, 320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 658)
[M::mem_pestat] mean and std.dev: (245.12, 119.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 827)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 499, 764)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1938)
[M::mem_pestat] mean and std.dev: (408.36, 388.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2525)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 409, 1429)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3845)
[M::mem_pestat] mean and std.dev: (838.37, 962.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5053)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704336 reads in 200.740 CPU sec, 6.407 real sec
sorting block 32, #reads = 1068189 mem = 536883326 peak = 1053925376
[M::process] read 710096 sequences (100000162 bp) in 1.992 CPU sec, 1.998 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 280699, 45, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 334, 1297)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3543)
[M::mem_pestat] mean and std.dev: (778.39, 961.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4666)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 223, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 670)
[M::mem_pestat] mean and std.dev: (247.63, 123.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 843)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (92, 578, 2028)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5900)
[M::mem_pestat] mean and std.dev: (1175.76, 1461.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7836)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 316, 853)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2129)
[M::mem_pestat] mean and std.dev: (496.42, 468.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2767)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704642 reads in 122.013 CPU sec, 4.002 real sec
[M::mem_process_seqs] Processed 704478 reads in 379.025 CPU sec, 12.167 real sec
sorting block 33, #reads = 1067360 mem = 536883461 peak = 1053925376
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (82, 280532, 45, 91)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (260, 581, 1268)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3284)
[M::mem_pestat] mean and std.dev: (828.59, 734.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4292)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 222, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 662)
[M::mem_pestat] mean and std.dev: (246.39, 120.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 832)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 487, 1297)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3463)
[M::mem_pestat] mean and std.dev: (685.59, 773.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4546)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (242, 444, 1339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3533)
[M::mem_pestat] mean and std.dev: (707.41, 621.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4630)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 708922 sequences (100000156 bp) in 2.190 CPU sec, 2.427 real sec...
[M::process] read 707680 sequences (100000238 bp) in 1.720 CPU sec, 1.722 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 282226, 40, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (223, 471, 1541)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4177)
[M::mem_pestat] mean and std.dev: (856.03, 835.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5495)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 212, 308)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 634)
[M::mem_pestat] mean and std.dev: (235.71, 116.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 797)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (97, 623, 1365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3901)
[M::mem_pestat] mean and std.dev: (711.58, 748.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5169)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 303, 793)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1943)
[M::mem_pestat] mean and std.dev: (440.04, 394.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2518)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704380 reads in 320.485 CPU sec, 10.307 real sec
sorting block 34, #reads = 1067755 mem = 536877570 peak = 1053925376
[M::mem_process_seqs] Processed 710096 reads in 146.780 CPU sec, 4.770 real sec
[M::process] read 706126 sequences (100000178 bp) in 2.599 CPU sec, 2.742 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 281634, 41, 85)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 362, 1114)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2918)
[M::mem_pestat] mean and std.dev: (667.27, 571.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3820)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 215, 312)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 644)
[M::mem_pestat] mean and std.dev: (238.41, 117.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 810)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 471, 1078)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2906)
[M::mem_pestat] mean and std.dev: (671.55, 778.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3820)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (296, 458, 1303)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3317)
[M::mem_pestat] mean and std.dev: (633.64, 588.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4324)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706140 sequences (100000122 bp) in 2.098 CPU sec, 2.099 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (92, 281372, 59, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 452, 1154)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3028)
[M::mem_pestat] mean and std.dev: (662.34, 648.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3965)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 218, 316)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 652)
[M::mem_pestat] mean and std.dev: (241.55, 119.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 820)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (380, 822, 1219)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2897)
[M::mem_pestat] mean and std.dev: (888.79, 677.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3736)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 351, 1451)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3945)
[M::mem_pestat] mean and std.dev: (684.60, 643.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5192)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 708922 reads in 198.575 CPU sec, 6.386 real sec
sorting block 35, #reads = 1071254 mem = 536879896 peak = 1053925376
[M::mem_process_seqs] Processed 707680 reads in 234.644 CPU sec, 7.474 real sec
sorting block 36, #reads = 1072140 mem = 536879889 peak = 1083502592
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 280834, 49, 77)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 494, 1151)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3071)
[M::mem_pestat] mean and std.dev: (634.38, 561.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4031)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 220, 317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 653)
[M::mem_pestat] mean and std.dev: (242.71, 119.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 821)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (336, 727, 2052)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5484)
[M::mem_pestat] mean and std.dev: (1110.50, 1184.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7200)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 323, 1088)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2840)
[M::mem_pestat] mean and std.dev: (607.36, 584.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3716)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705826 sequences (100000229 bp) in 2.927 CPU sec, 2.996 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (74, 281284, 48, 76)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 318, 984)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2584)
[M::mem_pestat] mean and std.dev: (554.33, 579.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3384)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 221, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 666)
[M::mem_pestat] mean and std.dev: (245.28, 121.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 838)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (712, 1036, 4662)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12562)
[M::mem_pestat] mean and std.dev: (2396.90, 2321.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 16512)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 423, 1041)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2749)
[M::mem_pestat] mean and std.dev: (594.73, 507.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3603)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705372 sequences (100000167 bp) in 2.290 CPU sec, 2.286 real sec...
[M::mem_process_seqs] Processed 706126 reads in 191.278 CPU sec, 6.043 real sec
[M::mem_process_seqs] Processed 706140 reads in 220.694 CPU sec, 7.060 real sec
sorting block 37, #reads = 1070918 mem = 536878998 peak = 1083502592
[M::process] read 704882 sequences (100000182 bp) in 2.276 CPU sec, 2.349 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 280861, 25, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (257, 396, 625)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1361)
[M::mem_pestat] mean and std.dev: (430.51, 280.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1729)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 222, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 666)
[M::mem_pestat] mean and std.dev: (246.10, 122.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 838)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (627, 1004, 1462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3132)
[M::mem_pestat] mean and std.dev: (1159.33, 798.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4352)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (281, 587, 1351)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3491)
[M::mem_pestat] mean and std.dev: (819.76, 731.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4561)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704690 sequences (100000139 bp) in 2.168 CPU sec, 2.168 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (99, 280552, 34, 87)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (243, 382, 999)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2511)
[M::mem_pestat] mean and std.dev: (487.40, 460.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3267)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 223, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 668)
[M::mem_pestat] mean and std.dev: (247.62, 122.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 840)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (603, 1296, 1590)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3564)
[M::mem_pestat] mean and std.dev: (1035.66, 617.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4551)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 406, 1127)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2951)
[M::mem_pestat] mean and std.dev: (638.71, 632.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3863)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 705826 reads in 197.744 CPU sec, 6.336 real sec
sorting block 38, #reads = 1071307 mem = 536881580 peak = 1083502592
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 280691, 33, 86)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (248, 452, 1140)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2924)
[M::mem_pestat] mean and std.dev: (619.60, 497.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3816)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 223, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 673)
[M::mem_pestat] mean and std.dev: (247.55, 122.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 847)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (106, 271, 1417)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4039)
[M::mem_pestat] mean and std.dev: (708.90, 858.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5350)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 267, 709)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1671)
[M::mem_pestat] mean and std.dev: (404.32, 301.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2152)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703316 sequences (100000110 bp) in 2.410 CPU sec, 2.412 real sec...
[M::mem_process_seqs] Processed 704882 reads in 224.041 CPU sec, 7.088 real sec
[M::mem_process_seqs] Processed 705372 reads in 254.893 CPU sec, 8.211 real sec
sorting block 39, #reads = 1070698 mem = 536879125 peak = 1083502592
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 279779, 48, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (226, 548, 972)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2464)
[M::mem_pestat] mean and std.dev: (574.27, 501.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3210)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 226, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 669)
[M::mem_pestat] mean and std.dev: (248.97, 122.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 841)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (504, 959, 2209)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5619)
[M::mem_pestat] mean and std.dev: (1141.07, 1149.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7324)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 420, 1403)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3879)
[M::mem_pestat] mean and std.dev: (678.84, 695.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5117)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704980 sequences (100000261 bp) in 3.166 CPU sec, 3.265 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 280764, 54, 93)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 315, 1015)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2601)
[M::mem_pestat] mean and std.dev: (642.32, 653.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3394)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 225, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 671)
[M::mem_pestat] mean and std.dev: (248.19, 122.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 844)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (381, 942, 2783)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7587)
[M::mem_pestat] mean and std.dev: (1517.85, 1556.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9989)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 370, 818)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2032)
[M::mem_pestat] mean and std.dev: (449.51, 384.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2639)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704678 sequences (100000235 bp) in 2.680 CPU sec, 2.682 real sec...
[M::mem_process_seqs] Processed 703316 reads in 204.295 CPU sec, 6.440 real sec
sorting block 40, #reads = 1069946 mem = 536877968 peak = 1083502592
[M::mem_process_seqs] Processed 704690 reads in 235.658 CPU sec, 7.669 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 280385, 51, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 268, 798)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1946)
[M::mem_pestat] mean and std.dev: (444.40, 413.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2520)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 221, 318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 652)
[M::mem_pestat] mean and std.dev: (243.51, 118.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 819)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (256, 450, 1095)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2773)
[M::mem_pestat] mean and std.dev: (631.89, 634.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3612)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 260, 1070)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2864)
[M::mem_pestat] mean and std.dev: (570.94, 626.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3761)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704592 sequences (100000120 bp) in 2.823 CPU sec, 2.930 real sec...
[M::process] read 704748 sequences (100000137 bp) in 2.270 CPU sec, 2.267 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (77, 280136, 51, 78)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 234, 647)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1589)
[M::mem_pestat] mean and std.dev: (395.07, 382.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2060)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 221, 317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 649)
[M::mem_pestat] mean and std.dev: (243.38, 118.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 815)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (386, 687, 1730)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4418)
[M::mem_pestat] mean and std.dev: (831.91, 762.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5762)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 408, 918)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2348)
[M::mem_pestat] mean and std.dev: (579.48, 572.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3063)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704980 reads in 200.416 CPU sec, 6.429 real sec
sorting block 41, #reads = 1070678 mem = 536878256 peak = 1083502592
[M::mem_process_seqs] Processed 704678 reads in 145.795 CPU sec, 4.635 real sec
sorting block 42, #reads = 1068319 mem = 536877612 peak = 1094766592
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (90, 280368, 43, 92)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (250, 530, 931)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2293)
[M::mem_pestat] mean and std.dev: (555.59, 385.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2974)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 221, 318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 652)
[M::mem_pestat] mean and std.dev: (244.16, 118.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 819)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (495, 756, 1963)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4899)
[M::mem_pestat] mean and std.dev: (1174.86, 922.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6367)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (234, 442, 1320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3492)
[M::mem_pestat] mean and std.dev: (703.93, 754.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4578)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704920 sequences (100000179 bp) in 2.662 CPU sec, 2.730 real sec...
[M::process] read 704762 sequences (100000094 bp) in 2.210 CPU sec, 2.211 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (79, 280716, 48, 77)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (230, 593, 1388)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3704)
[M::mem_pestat] mean and std.dev: (774.41, 766.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4862)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 221, 317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 649)
[M::mem_pestat] mean and std.dev: (243.29, 117.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 815)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 727, 2436)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6884)
[M::mem_pestat] mean and std.dev: (1283.23, 1569.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9108)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 289, 1188)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3134)
[M::mem_pestat] mean and std.dev: (611.51, 704.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4107)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704592 reads in 200.922 CPU sec, 6.366 real sec
[M::mem_process_seqs] Processed 704748 reads in 143.246 CPU sec, 4.642 real sec
sorting block 43, #reads = 1068808 mem = 536882788 peak = 1094766592
[M::process] read 703854 sequences (100000192 bp) in 2.723 CPU sec, 2.799 real sec...
[M::process] read 704932 sequences (100000093 bp) in 2.270 CPU sec, 2.266 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 280411, 55, 94)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 442, 1080)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2826)
[M::mem_pestat] mean and std.dev: (654.39, 567.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3699)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 221, 318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 652)
[M::mem_pestat] mean and std.dev: (244.03, 119.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 819)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (274, 848, 1761)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4735)
[M::mem_pestat] mean and std.dev: (1201.00, 1227.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6222)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 446, 1063)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2825)
[M::mem_pestat] mean and std.dev: (475.86, 401.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3706)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704762 reads in 116.647 CPU sec, 3.725 real sec
sorting block 44, #reads = 1067618 mem = 536882821 peak = 1094766592
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (84, 280611, 54, 82)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (302, 849, 1587)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4157)
[M::mem_pestat] mean and std.dev: (921.56, 793.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5442)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 222, 319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 655)
[M::mem_pestat] mean and std.dev: (244.48, 119.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 823)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (269, 747, 2120)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5822)
[M::mem_pestat] mean and std.dev: (1036.96, 1040.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7673)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (142, 279, 611)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1549)
[M::mem_pestat] mean and std.dev: (342.96, 301.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2018)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (87, 280200, 53, 77)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 336, 1074)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2788)
[M::mem_pestat] mean and std.dev: (530.48, 495.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3645)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 225, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 669)
[M::mem_pestat] mean and std.dev: (248.42, 122.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 841)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 800, 2800)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7980)
[M::mem_pestat] mean and std.dev: (1418.63, 1583.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10570)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 427, 930)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2360)
[M::mem_pestat] mean and std.dev: (561.20, 457.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3075)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 714124 sequences (100000080 bp) in 2.515 CPU sec, 2.521 real sec...
[M::mem_process_seqs] Processed 704920 reads in 324.360 CPU sec, 10.365 real sec
[M::mem_process_seqs] Processed 703854 reads in 183.906 CPU sec, 5.903 real sec
sorting block 45, #reads = 1070610 mem = 536882121 peak = 1094766592
[M::process] read 713602 sequences (100000026 bp) in 2.524 CPU sec, 2.622 real sec...
[M::process] read 711622 sequences (100000097 bp) in 2.250 CPU sec, 2.255 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 284217, 35, 76)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 388, 895)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2287)
[M::mem_pestat] mean and std.dev: (527.35, 551.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2983)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (141, 202, 292)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 594)
[M::mem_pestat] mean and std.dev: (225.53, 110.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 745)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (342, 489, 1077)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2547)
[M::mem_pestat] mean and std.dev: (607.55, 442.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3282)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (270, 684, 1327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3441)
[M::mem_pestat] mean and std.dev: (673.58, 581.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4498)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 714124 reads in 124.109 CPU sec, 3.944 real sec
sorting block 46, #reads = 1068049 mem = 536880587 peak = 1094766592
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (96, 280467, 41, 76)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (230, 352, 671)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1553)
[M::mem_pestat] mean and std.dev: (413.53, 292.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1994)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 220, 320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 658)
[M::mem_pestat] mean and std.dev: (244.48, 120.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 827)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (92, 720, 1761)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5099)
[M::mem_pestat] mean and std.dev: (847.95, 916.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6768)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 367, 751)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1849)
[M::mem_pestat] mean and std.dev: (447.29, 374.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2398)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 284476, 52, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 486, 910)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2360)
[M::mem_pestat] mean and std.dev: (581.78, 521.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3085)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (141, 204, 296)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 606)
[M::mem_pestat] mean and std.dev: (227.97, 112.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 761)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (407, 869, 1620)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4046)
[M::mem_pestat] mean and std.dev: (986.46, 728.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5259)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (257, 365, 1223)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3155)
[M::mem_pestat] mean and std.dev: (634.47, 676.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4121)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 709650 sequences (100000220 bp) in 1.945 CPU sec, 1.947 real sec...
[M::mem_process_seqs] Processed 704932 reads in 334.740 CPU sec, 10.624 real sec
[M::mem_process_seqs] Processed 713602 reads in 275.464 CPU sec, 8.769 real sec
sorting block 47, #reads = 1068973 mem = 536882770 peak = 1094766592
[M::process] read 708166 sequences (100000092 bp) in 2.716 CPU sec, 2.852 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (82, 283545, 52, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 401, 820)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2120)
[M::mem_pestat] mean and std.dev: (526.26, 478.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2770)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (143, 208, 302)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 620)
[M::mem_pestat] mean and std.dev: (232.50, 115.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 779)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (392, 546, 1462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3602)
[M::mem_pestat] mean and std.dev: (822.40, 692.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4672)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 362, 898)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2330)
[M::mem_pestat] mean and std.dev: (394.94, 297.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3046)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 708280 sequences (100000018 bp) in 1.950 CPU sec, 1.952 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 283587, 47, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 326, 1141)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3081)
[M::mem_pestat] mean and std.dev: (787.77, 799.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4051)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 213, 310)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 638)
[M::mem_pestat] mean and std.dev: (237.61, 118.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 802)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (130, 761, 1850)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5290)
[M::mem_pestat] mean and std.dev: (1066.11, 1126.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7010)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 391, 711)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1759)
[M::mem_pestat] mean and std.dev: (415.19, 340.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2283)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 711622 reads in 207.530 CPU sec, 6.584 real sec
sorting block 48, #reads = 1071038 mem = 536886229 peak = 1094766592
[M::mem_process_seqs] Processed 709650 reads in 237.816 CPU sec, 7.821 real sec
[M::process] read 707768 sequences (100000062 bp) in 2.830 CPU sec, 2.917 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 282439, 37, 82)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 339, 704)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1790)
[M::mem_pestat] mean and std.dev: (445.79, 386.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2333)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 215, 315)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 651)
[M::mem_pestat] mean and std.dev: (241.37, 121.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 819)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (396, 1477, 6438)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 18522)
[M::mem_pestat] mean and std.dev: (2960.30, 3014.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 24564)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 323, 822)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2094)
[M::mem_pestat] mean and std.dev: (510.70, 470.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2730)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 708166 reads in 122.738 CPU sec, 4.178 real sec
sorting block 49, #reads = 1072136 mem = 536880237 peak = 1094766592
[M::process] read 707600 sequences (100000038 bp) in 2.732 CPU sec, 2.855 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 282677, 40, 74)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 371, 959)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2433)
[M::mem_pestat] mean and std.dev: (526.50, 447.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3170)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 216, 316)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 654)
[M::mem_pestat] mean and std.dev: (241.84, 121.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 823)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (317, 890, 1765)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4661)
[M::mem_pestat] mean and std.dev: (1124.26, 990.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6109)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 361, 856)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2126)
[M::mem_pestat] mean and std.dev: (433.84, 313.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2761)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 707740 sequences (100000261 bp) in 2.310 CPU sec, 2.316 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 282412, 39, 100)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 279, 630)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1488)
[M::mem_pestat] mean and std.dev: (365.98, 293.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1917)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 216, 317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 655)
[M::mem_pestat] mean and std.dev: (242.14, 120.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 824)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 333, 930)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2476)
[M::mem_pestat] mean and std.dev: (379.36, 319.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3249)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 452, 1143)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3001)
[M::mem_pestat] mean and std.dev: (708.22, 656.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3930)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 708280 reads in 243.146 CPU sec, 7.763 real sec
sorting block 50, #reads = 1070020 mem = 536878254 peak = 1094766592
[M::mem_process_seqs] Processed 707768 reads in 272.796 CPU sec, 8.802 real sec
[M::process] read 706722 sequences (100000141 bp) in 2.644 CPU sec, 2.763 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (80, 281499, 43, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 310, 500)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1072)
[M::mem_pestat] mean and std.dev: (285.69, 146.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1358)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 216, 317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 655)
[M::mem_pestat] mean and std.dev: (242.13, 121.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 824)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (307, 912, 4574)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13108)
[M::mem_pestat] mean and std.dev: (2204.23, 2487.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17375)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 362, 1233)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3315)
[M::mem_pestat] mean and std.dev: (712.05, 701.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4356)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705852 sequences (100000052 bp) in 2.210 CPU sec, 2.216 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (83, 282162, 41, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (251, 376, 1362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3584)
[M::mem_pestat] mean and std.dev: (775.91, 830.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4695)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 216, 314)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 646)
[M::mem_pestat] mean and std.dev: (240.66, 119.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 812)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (428, 1183, 1977)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5075)
[M::mem_pestat] mean and std.dev: (1187.40, 928.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6624)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 427, 1515)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4153)
[M::mem_pestat] mean and std.dev: (778.46, 794.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5472)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 707600 reads in 213.047 CPU sec, 6.838 real sec
sorting block 51, #reads = 1067145 mem = 536890912 peak = 1094766592
[M::mem_process_seqs] Processed 707740 reads in 244.879 CPU sec, 7.801 real sec
sorting block 52, #reads = 1068357 mem = 536880109 peak = 1094766592
[M::process] read 705710 sequences (100000021 bp) in 2.928 CPU sec, 2.997 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (94, 280808, 30, 101)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (322, 645, 926)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2134)
[M::mem_pestat] mean and std.dev: (633.91, 461.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2738)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 219, 320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 660)
[M::mem_pestat] mean and std.dev: (245.10, 122.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 830)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 576, 1118)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2946)
[M::mem_pestat] mean and std.dev: (638.63, 532.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3860)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (230, 364, 663)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1529)
[M::mem_pestat] mean and std.dev: (444.13, 349.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1962)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704816 sequences (100000101 bp) in 2.300 CPU sec, 2.299 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 281464, 47, 85)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 409, 1341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3681)
[M::mem_pestat] mean and std.dev: (686.32, 744.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4851)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 218, 317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 653)
[M::mem_pestat] mean and std.dev: (243.22, 121.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 821)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (122, 382, 1292)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3632)
[M::mem_pestat] mean and std.dev: (723.52, 773.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4802)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (335, 542, 1351)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3383)
[M::mem_pestat] mean and std.dev: (761.94, 671.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4399)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 705852 reads in 216.883 CPU sec, 6.884 real sec
[M::mem_process_seqs] Processed 706722 reads in 248.209 CPU sec, 7.908 real sec
sorting block 53, #reads = 1066916 mem = 536877491 peak = 1094766592
[M::process] read 704778 sequences (100000177 bp) in 2.745 CPU sec, 2.820 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 280986, 52, 79)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 379, 1033)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2717)
[M::mem_pestat] mean and std.dev: (593.94, 571.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3559)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 219, 318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 654)
[M::mem_pestat] mean and std.dev: (244.07, 121.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 822)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (370, 669, 2570)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6970)
[M::mem_pestat] mean and std.dev: (1232.33, 1474.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9170)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (260, 801, 1437)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3791)
[M::mem_pestat] mean and std.dev: (846.42, 752.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4968)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704206 sequences (100000069 bp) in 1.798 CPU sec, 1.801 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 280256, 39, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 268, 627)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1563)
[M::mem_pestat] mean and std.dev: (317.59, 246.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2031)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 221, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 661)
[M::mem_pestat] mean and std.dev: (245.73, 121.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 831)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (391, 774, 2258)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5992)
[M::mem_pestat] mean and std.dev: (1262.49, 1161.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7859)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 368, 1100)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2882)
[M::mem_pestat] mean and std.dev: (605.15, 622.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3773)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (95, 280769, 58, 83)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (230, 356, 776)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1868)
[M::mem_pestat] mean and std.dev: (510.14, 438.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2414)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 221, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 664)
[M::mem_pestat] mean and std.dev: (246.42, 122.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 835)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 451, 1070)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2778)
[M::mem_pestat] mean and std.dev: (658.09, 573.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3632)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 340, 552)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1218)
[M::mem_pestat] mean and std.dev: (369.73, 216.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1551)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 705710 reads in 303.772 CPU sec, 9.686 real sec
sorting block 54, #reads = 1065873 mem = 536885020 peak = 1094766592
[M::mem_process_seqs] Processed 704816 reads in 240.282 CPU sec, 7.707 real sec
[M::mem_process_seqs] Processed 704778 reads in 274.328 CPU sec, 8.803 real sec
sorting block 55, #reads = 1064482 mem = 536877025 peak = 1094766592
[M::process] read 714132 sequences (100000301 bp) in 3.324 CPU sec, 3.448 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (89, 280303, 43, 100)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (239, 355, 1112)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2858)
[M::mem_pestat] mean and std.dev: (557.37, 466.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3731)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 223, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 668)
[M::mem_pestat] mean and std.dev: (247.73, 123.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 840)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (379, 1110, 2661)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7225)
[M::mem_pestat] mean and std.dev: (1595.51, 1697.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9507)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 409, 1117)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2981)
[M::mem_pestat] mean and std.dev: (636.98, 613.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3913)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 715716 sequences (100000150 bp) in 2.583 CPU sec, 2.609 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 283378, 44, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 276, 1082)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2848)
[M::mem_pestat] mean and std.dev: (491.71, 436.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3731)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (141, 202, 293)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 597)
[M::mem_pestat] mean and std.dev: (225.89, 110.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 749)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (256, 484, 1415)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3733)
[M::mem_pestat] mean and std.dev: (579.24, 645.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4892)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (245, 373, 757)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1781)
[M::mem_pestat] mean and std.dev: (470.19, 358.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2293)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704206 reads in 224.558 CPU sec, 7.091 real sec
[M::process] read 714036 sequences (100000163 bp) in 2.237 CPU sec, 2.244 real sec...
sorting block 56, #reads = 1064664 mem = 536883593 peak = 1094766592
[M::mem_process_seqs] Processed 714132 reads in 169.579 CPU sec, 5.337 real sec
sorting block 57, #reads = 1063615 mem = 536878455 peak = 1094766592
[M::process] read 713138 sequences (100000254 bp) in 2.905 CPU sec, 2.984 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (73, 284119, 47, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 347, 791)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2033)
[M::mem_pestat] mean and std.dev: (448.45, 377.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2654)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (139, 201, 289)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 589)
[M::mem_pestat] mean and std.dev: (223.63, 109.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 739)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (413, 630, 1440)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3494)
[M::mem_pestat] mean and std.dev: (948.78, 837.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4521)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 403, 1430)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3862)
[M::mem_pestat] mean and std.dev: (751.44, 762.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5078)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 711412 sequences (100000147 bp) in 2.350 CPU sec, 2.350 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 283882, 53, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (244, 407, 1363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3601)
[M::mem_pestat] mean and std.dev: (637.94, 701.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4720)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (141, 204, 296)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 606)
[M::mem_pestat] mean and std.dev: (227.76, 111.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 761)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (482, 1057, 1807)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4457)
[M::mem_pestat] mean and std.dev: (970.71, 775.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5782)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 249, 658)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1580)
[M::mem_pestat] mean and std.dev: (397.44, 343.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2041)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 715716 reads in 240.198 CPU sec, 7.607 real sec
[M::mem_process_seqs] Processed 714036 reads in 275.195 CPU sec, 8.742 real sec
sorting block 58, #reads = 1065390 mem = 536880173 peak = 1094766592
[M::process] read 710606 sequences (100000030 bp) in 2.481 CPU sec, 2.570 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 283723, 32, 72)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 298, 760)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1888)
[M::mem_pestat] mean and std.dev: (455.39, 434.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2452)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (142, 206, 299)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 613)
[M::mem_pestat] mean and std.dev: (229.85, 112.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 770)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (260, 1013, 1837)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4991)
[M::mem_pestat] mean and std.dev: (1207.88, 1148.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6568)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (233, 359, 1026)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2612)
[M::mem_pestat] mean and std.dev: (541.83, 480.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3405)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 709508 sequences (100000128 bp) in 1.810 CPU sec, 1.808 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (73, 283727, 39, 82)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 418, 1538)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4182)
[M::mem_pestat] mean and std.dev: (878.08, 1018.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5504)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (144, 208, 302)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 618)
[M::mem_pestat] mean and std.dev: (232.30, 114.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 776)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (354, 757, 1354)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3354)
[M::mem_pestat] mean and std.dev: (870.30, 656.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4354)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 333, 951)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2455)
[M::mem_pestat] mean and std.dev: (532.18, 478.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3207)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 713138 reads in 235.550 CPU sec, 7.494 real sec
sorting block 59, #reads = 1061090 mem = 536881744 peak = 1094766592
[M::mem_process_seqs] Processed 711412 reads in 269.511 CPU sec, 8.598 real sec
[M::process] read 709516 sequences (100000270 bp) in 2.364 CPU sec, 2.437 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 283376, 51, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (237, 534, 2316)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6474)
[M::mem_pestat] mean and std.dev: (1296.65, 1646.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8553)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 210, 307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 631)
[M::mem_pestat] mean and std.dev: (235.16, 116.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 793)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (450, 753, 1296)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2988)
[M::mem_pestat] mean and std.dev: (797.07, 625.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3834)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 460, 952)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2406)
[M::mem_pestat] mean and std.dev: (527.96, 429.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3133)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 707900 sequences (100000068 bp) in 1.750 CPU sec, 1.746 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (86, 282583, 49, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 256, 823)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2171)
[M::mem_pestat] mean and std.dev: (487.82, 472.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2845)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 212, 309)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 635)
[M::mem_pestat] mean and std.dev: (237.33, 117.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 798)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (468, 1177, 3188)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8628)
[M::mem_pestat] mean and std.dev: (2030.90, 2135.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11348)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (239, 410, 834)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2024)
[M::mem_pestat] mean and std.dev: (504.74, 397.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2619)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 710606 reads in 229.830 CPU sec, 7.310 real sec
sorting block 60, #reads = 1065204 mem = 536882161 peak = 1094766592
[M::mem_process_seqs] Processed 709508 reads in 264.649 CPU sec, 8.438 real sec
sorting block 61, #reads = 1067231 mem = 536881719 peak = 1094766592
[M::process] read 708140 sequences (100000058 bp) in 2.803 CPU sec, 2.860 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 282783, 54, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 727, 1501)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4103)
[M::mem_pestat] mean and std.dev: (919.21, 823.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5404)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 212, 308)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 632)
[M::mem_pestat] mean and std.dev: (236.87, 117.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 794)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (388, 731, 1385)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3379)
[M::mem_pestat] mean and std.dev: (870.94, 728.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4376)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 368, 1015)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2619)
[M::mem_pestat] mean and std.dev: (602.36, 523.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3421)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706292 sequences (100000148 bp) in 2.420 CPU sec, 2.424 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (88, 281992, 46, 83)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 388, 979)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2563)
[M::mem_pestat] mean and std.dev: (570.99, 552.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3355)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 215, 312)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 642)
[M::mem_pestat] mean and std.dev: (239.56, 118.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 807)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (321, 727, 1609)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4185)
[M::mem_pestat] mean and std.dev: (928.61, 792.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5473)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (271, 531, 1017)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2509)
[M::mem_pestat] mean and std.dev: (684.89, 554.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3255)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 709516 reads in 232.227 CPU sec, 7.351 real sec
[M::mem_process_seqs] Processed 707900 reads in 268.311 CPU sec, 8.532 real sec
sorting block 62, #reads = 1064692 mem = 536882085 peak = 1094766592
[M::process] read 705954 sequences (100000105 bp) in 2.267 CPU sec, 2.337 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 281487, 45, 72)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 630, 1289)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3425)
[M::mem_pestat] mean and std.dev: (760.25, 695.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4493)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 214, 311)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 639)
[M::mem_pestat] mean and std.dev: (238.82, 118.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 803)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (300, 534, 1069)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2607)
[M::mem_pestat] mean and std.dev: (589.73, 518.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3376)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 440, 1227)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3279)
[M::mem_pestat] mean and std.dev: (804.64, 801.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4305)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705174 sequences (100000192 bp) in 1.900 CPU sec, 1.898 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 281088, 57, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 386, 615)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1439)
[M::mem_pestat] mean and std.dev: (379.49, 247.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1851)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 218, 319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 659)
[M::mem_pestat] mean and std.dev: (244.62, 123.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 829)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (326, 639, 2404)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6560)
[M::mem_pestat] mean and std.dev: (1347.91, 1476.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8638)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (252, 542, 1605)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4311)
[M::mem_pestat] mean and std.dev: (859.38, 859.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5664)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (92, 280860, 48, 85)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 381, 1697)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4701)
[M::mem_pestat] mean and std.dev: (963.27, 1135.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6203)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 219, 319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 659)
[M::mem_pestat] mean and std.dev: (244.32, 122.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 829)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (504, 966, 1927)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4773)
[M::mem_pestat] mean and std.dev: (1414.42, 1280.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6536)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (340, 644, 1449)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3667)
[M::mem_pestat] mean and std.dev: (656.29, 516.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4776)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 708140 reads in 304.620 CPU sec, 9.724 real sec
sorting block 63, #reads = 1065572 mem = 536885382 peak = 1094766592
[M::mem_process_seqs] Processed 705954 reads in 243.837 CPU sec, 7.836 real sec
[M::mem_process_seqs] Processed 706292 reads in 277.797 CPU sec, 8.922 real sec
sorting block 64, #reads = 1065760 mem = 536885921 peak = 1094766592
[M::process] read 705124 sequences (100000268 bp) in 3.142 CPU sec, 3.300 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (96, 280460, 38, 74)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 315, 918)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2388)
[M::mem_pestat] mean and std.dev: (562.36, 578.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3123)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 220, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 666)
[M::mem_pestat] mean and std.dev: (246.42, 123.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 838)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (119, 557, 1435)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4067)
[M::mem_pestat] mean and std.dev: (788.56, 818.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5383)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 436, 1060)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2760)
[M::mem_pestat] mean and std.dev: (632.38, 578.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3610)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 710712 sequences (100000052 bp) in 2.589 CPU sec, 2.614 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (88, 279847, 43, 91)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 382, 1395)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3775)
[M::mem_pestat] mean and std.dev: (890.63, 946.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4965)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 221, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 670)
[M::mem_pestat] mean and std.dev: (247.48, 124.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 843)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 584, 1046)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2726)
[M::mem_pestat] mean and std.dev: (602.80, 522.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3566)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (238, 423, 759)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1801)
[M::mem_pestat] mean and std.dev: (460.04, 325.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2322)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 712466 sequences (100000300 bp) in 1.780 CPU sec, 1.784 real sec...
[M::mem_process_seqs] Processed 705174 reads in 227.450 CPU sec, 7.212 real sec
sorting block 65, #reads = 1065045 mem = 536880238 peak = 1094766592
[M::mem_process_seqs] Processed 705124 reads in 165.683 CPU sec, 5.252 real sec
[M::process] read 710802 sequences (100000089 bp) in 2.745 CPU sec, 2.848 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (90, 282370, 54, 80)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 501, 1228)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3274)
[M::mem_pestat] mean and std.dev: (693.88, 636.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4297)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (144, 209, 303)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 621)
[M::mem_pestat] mean and std.dev: (233.25, 115.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 780)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (238, 712, 1296)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3412)
[M::mem_pestat] mean and std.dev: (794.46, 690.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4470)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (306, 694, 1645)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4323)
[M::mem_pestat] mean and std.dev: (1057.64, 1070.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5662)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 708880 sequences (100000096 bp) in 2.400 CPU sec, 2.398 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 283000, 55, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 314, 676)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1674)
[M::mem_pestat] mean and std.dev: (389.39, 326.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2173)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (143, 207, 299)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 611)
[M::mem_pestat] mean and std.dev: (230.25, 113.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 767)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (616, 933, 1636)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3676)
[M::mem_pestat] mean and std.dev: (1049.41, 802.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4696)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (239, 354, 1236)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3230)
[M::mem_pestat] mean and std.dev: (655.42, 671.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4227)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 710712 reads in 242.272 CPU sec, 7.685 real sec
sorting block 66, #reads = 1059494 mem = 536880781 peak = 1094766592
[M::mem_process_seqs] Processed 712466 reads in 277.275 CPU sec, 8.830 real sec
sorting block 67, #reads = 1066083 mem = 536886136 peak = 1094766592
[M::process] read 708666 sequences (100000087 bp) in 2.376 CPU sec, 2.444 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 283007, 44, 79)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 374, 638)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1576)
[M::mem_pestat] mean and std.dev: (345.09, 233.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2045)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (144, 210, 305)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 627)
[M::mem_pestat] mean and std.dev: (233.88, 115.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 788)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (286, 731, 1417)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3679)
[M::mem_pestat] mean and std.dev: (924.91, 790.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4810)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (239, 382, 879)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2159)
[M::mem_pestat] mean and std.dev: (548.83, 488.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2799)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 707368 sequences (100000188 bp) in 2.299 CPU sec, 2.297 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (77, 282495, 43, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (223, 410, 1007)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2575)
[M::mem_pestat] mean and std.dev: (617.88, 556.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3359)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 214, 311)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 641)
[M::mem_pestat] mean and std.dev: (238.05, 117.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 806)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (286, 639, 1354)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3490)
[M::mem_pestat] mean and std.dev: (908.66, 870.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4558)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (235, 415, 1481)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3973)
[M::mem_pestat] mean and std.dev: (918.15, 939.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5219)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 282327, 36, 76)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 282, 794)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2028)
[M::mem_pestat] mean and std.dev: (409.81, 391.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2645)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 214, 311)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 641)
[M::mem_pestat] mean and std.dev: (238.85, 119.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 806)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (339, 795, 1871)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4935)
[M::mem_pestat] mean and std.dev: (1111.85, 1161.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6467)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 429, 937)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2449)
[M::mem_pestat] mean and std.dev: (547.01, 430.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3205)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 710802 reads in 295.432 CPU sec, 9.416 real sec
[M::mem_process_seqs] Processed 708880 reads in 231.881 CPU sec, 7.433 real sec
sorting block 68, #reads = 1071552 mem = 536879581 peak = 1094766592
[M::process] read 707910 sequences (100000102 bp) in 3.173 CPU sec, 3.247 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (80, 282060, 40, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (223, 418, 1062)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2740)
[M::mem_pestat] mean and std.dev: (591.12, 518.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3579)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 216, 315)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 649)
[M::mem_pestat] mean and std.dev: (241.31, 119.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 816)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (330, 600, 1549)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3987)
[M::mem_pestat] mean and std.dev: (813.84, 629.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5206)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 470, 1208)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3136)
[M::mem_pestat] mean and std.dev: (670.23, 641.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4100)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 707368 reads in 124.150 CPU sec, 3.899 real sec
[M::process] read 707376 sequences (100000053 bp) in 2.632 CPU sec, 2.692 real sec...
sorting block 69, #reads = 1069859 mem = 536879152 peak = 1094766592
[M::mem_process_seqs] Processed 708666 reads in 437.624 CPU sec, 13.941 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (85, 282560, 43, 83)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 289, 716)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1754)
[M::mem_pestat] mean and std.dev: (456.71, 396.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2273)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 216, 314)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 648)
[M::mem_pestat] mean and std.dev: (240.46, 119.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 815)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (570, 1009, 1601)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3663)
[M::mem_pestat] mean and std.dev: (923.34, 569.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4694)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (246, 459, 1225)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3183)
[M::mem_pestat] mean and std.dev: (662.05, 607.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4162)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706310 sequences (100000193 bp) in 2.734 CPU sec, 2.821 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 282105, 44, 78)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 330, 714)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1794)
[M::mem_pestat] mean and std.dev: (358.96, 303.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2334)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 216, 315)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 649)
[M::mem_pestat] mean and std.dev: (241.37, 119.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 816)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (606, 1214, 2670)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6798)
[M::mem_pestat] mean and std.dev: (1578.02, 1697.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8862)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (257, 403, 1243)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3215)
[M::mem_pestat] mean and std.dev: (569.20, 549.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4201)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706200 sequences (100000154 bp) in 2.240 CPU sec, 2.240 real sec...
[M::mem_process_seqs] Processed 707910 reads in 257.050 CPU sec, 8.099 real sec
sorting block 70, #reads = 1070516 mem = 536882430 peak = 1094766592
[M::mem_process_seqs] Processed 707376 reads in 158.341 CPU sec, 5.012 real sec
sorting block 71, #reads = 1067351 mem = 536879864 peak = 1097932800
[M::process] read 705838 sequences (100000265 bp) in 2.415 CPU sec, 2.504 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 280914, 50, 78)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 290, 992)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2588)
[M::mem_pestat] mean and std.dev: (566.84, 557.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3386)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 219, 320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 660)
[M::mem_pestat] mean and std.dev: (244.58, 122.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 830)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (541, 849, 1206)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2536)
[M::mem_pestat] mean and std.dev: (871.89, 616.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3339)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 366, 1111)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2897)
[M::mem_pestat] mean and std.dev: (617.32, 610.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3790)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705246 sequences (100000148 bp) in 2.080 CPU sec, 2.075 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (74, 281152, 62, 79)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 465, 664)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1550)
[M::mem_pestat] mean and std.dev: (450.06, 328.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1993)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 219, 319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 659)
[M::mem_pestat] mean and std.dev: (244.14, 121.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 829)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 595, 1334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3640)
[M::mem_pestat] mean and std.dev: (815.45, 741.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4793)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 424, 956)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2452)
[M::mem_pestat] mean and std.dev: (510.11, 447.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3200)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 706200 reads in 214.930 CPU sec, 6.820 real sec
[M::mem_process_seqs] Processed 706310 reads in 247.206 CPU sec, 7.972 real sec
sorting block 72, #reads = 1066921 mem = 536879011 peak = 1097932800
[M::process] read 705144 sequences (100000250 bp) in 2.999 CPU sec, 3.087 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (87, 280640, 62, 91)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (227, 402, 1083)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2795)
[M::mem_pestat] mean and std.dev: (595.88, 533.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3651)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 220, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 663)
[M::mem_pestat] mean and std.dev: (245.89, 122.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 834)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (122, 416, 1624)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4628)
[M::mem_pestat] mean and std.dev: (859.23, 905.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6130)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (295, 584, 1279)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3247)
[M::mem_pestat] mean and std.dev: (820.74, 709.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4231)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705640 sequences (100000294 bp) in 2.270 CPU sec, 2.267 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (89, 280969, 48, 76)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 301, 995)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2573)
[M::mem_pestat] mean and std.dev: (506.56, 494.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3362)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 220, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 663)
[M::mem_pestat] mean and std.dev: (245.23, 122.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 834)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (237, 534, 1768)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4830)
[M::mem_pestat] mean and std.dev: (873.04, 916.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6361)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 464, 1014)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2668)
[M::mem_pestat] mean and std.dev: (659.96, 620.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3495)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 705246 reads in 217.546 CPU sec, 6.881 real sec
[M::mem_process_seqs] Processed 705838 reads in 249.576 CPU sec, 7.955 real sec
sorting block 73, #reads = 1066038 mem = 536878343 peak = 1097932800
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 279931, 38, 98)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 398, 1332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3638)
[M::mem_pestat] mean and std.dev: (655.75, 583.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4791)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 220, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 661)
[M::mem_pestat] mean and std.dev: (245.58, 122.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 831)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (291, 808, 1588)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4182)
[M::mem_pestat] mean and std.dev: (1034.67, 1013.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5479)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 306, 776)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1938)
[M::mem_pestat] mean and std.dev: (419.01, 357.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2519)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704846 sequences (100000122 bp) in 2.900 CPU sec, 2.969 real sec...
[M::process] read 709960 sequences (100000278 bp) in 2.480 CPU sec, 2.487 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (76, 280339, 36, 80)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (243, 438, 984)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2466)
[M::mem_pestat] mean and std.dev: (616.46, 512.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3207)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 219, 318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 654)
[M::mem_pestat] mean and std.dev: (243.77, 121.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 822)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (135, 378, 936)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2538)
[M::mem_pestat] mean and std.dev: (496.27, 490.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3339)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 410, 1066)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2774)
[M::mem_pestat] mean and std.dev: (667.75, 692.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3628)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 705144 reads in 218.101 CPU sec, 6.898 real sec
sorting block 74, #reads = 1065181 mem = 536886615 peak = 1097932800
[M::mem_process_seqs] Processed 705640 reads in 156.849 CPU sec, 4.993 real sec
sorting block 75, #reads = 1063360 mem = 536883537 peak = 1097932800
[M::process] read 718156 sequences (100000239 bp) in 2.867 CPU sec, 2.954 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 280280, 52, 99)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (278, 583, 1037)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2555)
[M::mem_pestat] mean and std.dev: (610.32, 474.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3314)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 221, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 661)
[M::mem_pestat] mean and std.dev: (245.90, 122.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 831)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (325, 634, 1231)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3043)
[M::mem_pestat] mean and std.dev: (872.02, 812.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4120)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (269, 451, 912)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2198)
[M::mem_pestat] mean and std.dev: (520.83, 385.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2841)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 714010 sequences (100000183 bp) in 2.698 CPU sec, 2.702 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (74, 284976, 34, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 430, 1144)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3020)
[M::mem_pestat] mean and std.dev: (662.15, 571.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3958)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 196, 282)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 572)
[M::mem_pestat] mean and std.dev: (218.84, 106.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 717)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (417, 923, 1911)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4899)
[M::mem_pestat] mean and std.dev: (1154.16, 1035.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6393)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 278, 949)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2501)
[M::mem_pestat] mean and std.dev: (569.20, 589.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3277)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 281161, 33, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 323, 1502)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4100)
[M::mem_pestat] mean and std.dev: (649.92, 695.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5399)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 210, 306)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 628)
[M::mem_pestat] mean and std.dev: (235.21, 116.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 789)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (445, 810, 1848)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4654)
[M::mem_pestat] mean and std.dev: (963.97, 824.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6057)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 308, 593)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1381)
[M::mem_pestat] mean and std.dev: (380.69, 286.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1775)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704846 reads in 351.101 CPU sec, 11.184 real sec
[M::mem_process_seqs] Processed 718156 reads in 287.346 CPU sec, 9.187 real sec
sorting block 76, #reads = 1061775 mem = 536890321 peak = 1097932800
[M::mem_process_seqs] Processed 709960 reads in 331.683 CPU sec, 10.593 real sec
[M::process] read 712068 sequences (100000035 bp) in 3.254 CPU sec, 3.382 real sec...
sorting block 77, #reads = 1056875 mem = 536881298 peak = 1097932800
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 283526, 52, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 276, 834)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2140)
[M::mem_pestat] mean and std.dev: (502.29, 518.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2793)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (141, 203, 295)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 603)
[M::mem_pestat] mean and std.dev: (227.15, 111.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 757)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (246, 483, 1348)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3552)
[M::mem_pestat] mean and std.dev: (778.06, 708.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4654)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 399, 1318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3526)
[M::mem_pestat] mean and std.dev: (788.27, 814.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4630)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 711236 sequences (100000097 bp) in 2.311 CPU sec, 2.338 real sec...
[M::process] read 709608 sequences (100000023 bp) in 1.760 CPU sec, 1.759 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (78, 283139, 45, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 321, 703)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1753)
[M::mem_pestat] mean and std.dev: (376.97, 289.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2278)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (143, 208, 302)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 620)
[M::mem_pestat] mean and std.dev: (232.08, 114.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 779)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 478, 1762)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4968)
[M::mem_pestat] mean and std.dev: (858.35, 906.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6571)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 318, 810)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2016)
[M::mem_pestat] mean and std.dev: (425.42, 321.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2619)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 714010 reads in 245.715 CPU sec, 7.800 real sec
[M::mem_process_seqs] Processed 712068 reads in 173.414 CPU sec, 5.528 real sec
sorting block 78, #reads = 1064443 mem = 536885579 peak = 1097932800
[M::process] read 709284 sequences (100000127 bp) in 3.292 CPU sec, 3.391 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 282984, 48, 88)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 521, 1014)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2598)
[M::mem_pestat] mean and std.dev: (593.84, 468.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3390)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (144, 208, 303)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 621)
[M::mem_pestat] mean and std.dev: (233.16, 115.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 780)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (338, 687, 1230)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3014)
[M::mem_pestat] mean and std.dev: (775.66, 542.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3906)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (254, 458, 1280)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3332)
[M::mem_pestat] mean and std.dev: (772.81, 784.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4358)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 707046 sequences (100000020 bp) in 2.300 CPU sec, 2.301 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (78, 282072, 38, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 279, 632)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1518)
[M::mem_pestat] mean and std.dev: (362.28, 309.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1961)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 211, 307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 631)
[M::mem_pestat] mean and std.dev: (236.24, 117.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 793)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 566, 1311)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3557)
[M::mem_pestat] mean and std.dev: (773.36, 879.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4680)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 467, 851)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2101)
[M::mem_pestat] mean and std.dev: (538.49, 421.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2726)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 711236 reads in 245.822 CPU sec, 7.793 real sec
sorting block 79, #reads = 1061030 mem = 536879867 peak = 1097932800
[M::process] read 706766 sequences (100000096 bp) in 2.420 CPU sec, 2.425 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (77, 282175, 54, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 397, 1188)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3124)
[M::mem_pestat] mean and std.dev: (569.37, 599.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4092)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 212, 307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 629)
[M::mem_pestat] mean and std.dev: (236.33, 116.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 790)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (474, 1025, 1809)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4479)
[M::mem_pestat] mean and std.dev: (947.77, 707.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5814)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 384, 890)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2286)
[M::mem_pestat] mean and std.dev: (534.66, 461.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2984)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 709284 reads in 137.684 CPU sec, 4.366 real sec
[M::mem_process_seqs] Processed 709608 reads in 449.119 CPU sec, 14.290 real sec
sorting block 80, #reads = 1063909 mem = 536879197 peak = 1097932800
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (85, 281263, 57, 75)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (256, 428, 1062)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2674)
[M::mem_pestat] mean and std.dev: (613.52, 483.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3480)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 217, 315)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 647)
[M::mem_pestat] mean and std.dev: (241.62, 119.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 813)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (86, 413, 787)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2189)
[M::mem_pestat] mean and std.dev: (493.39, 511.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2890)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 340, 1195)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3157)
[M::mem_pestat] mean and std.dev: (683.84, 665.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4138)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706548 sequences (100000291 bp) in 2.659 CPU sec, 2.713 real sec...
[M::process] read 705840 sequences (100000159 bp) in 1.720 CPU sec, 1.727 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 280545, 32, 80)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 291, 1509)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4181)
[M::mem_pestat] mean and std.dev: (814.86, 1051.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5517)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 217, 315)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 647)
[M::mem_pestat] mean and std.dev: (241.44, 119.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 813)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 620, 1927)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5431)
[M::mem_pestat] mean and std.dev: (887.19, 945.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7183)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 377, 1423)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3839)
[M::mem_pestat] mean and std.dev: (720.71, 747.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5047)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 707046 reads in 267.549 CPU sec, 8.529 real sec
sorting block 81, #reads = 1064317 mem = 536884403 peak = 1097932800
[M::mem_process_seqs] Processed 706766 reads in 168.658 CPU sec, 5.376 real sec
[M::process] read 705620 sequences (100000129 bp) in 2.969 CPU sec, 3.070 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (101, 280857, 53, 75)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 478, 1096)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2906)
[M::mem_pestat] mean and std.dev: (653.64, 567.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3811)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 217, 315)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 647)
[M::mem_pestat] mean and std.dev: (241.68, 119.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 813)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (308, 805, 1145)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2819)
[M::mem_pestat] mean and std.dev: (737.43, 498.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3656)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 428, 874)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2168)
[M::mem_pestat] mean and std.dev: (535.19, 429.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2815)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705896 sequences (100000222 bp) in 2.300 CPU sec, 2.300 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (88, 280620, 41, 84)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (245, 580, 1021)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2573)
[M::mem_pestat] mean and std.dev: (662.20, 598.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3349)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 218, 316)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 648)
[M::mem_pestat] mean and std.dev: (242.63, 119.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 814)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (292, 626, 1784)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4768)
[M::mem_pestat] mean and std.dev: (1063.22, 1116.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6260)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 439, 986)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2506)
[M::mem_pestat] mean and std.dev: (570.95, 485.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3266)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 706548 reads in 223.354 CPU sec, 7.068 real sec
sorting block 82, #reads = 1062645 mem = 536881056 peak = 1097932800
[M::mem_process_seqs] Processed 705840 reads in 254.702 CPU sec, 8.092 real sec
sorting block 83, #reads = 1064837 mem = 536879184 peak = 1121685504
[M::process] read 705252 sequences (100000006 bp) in 2.426 CPU sec, 2.479 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (88, 280718, 37, 79)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 416, 944)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2426)
[M::mem_pestat] mean and std.dev: (620.34, 594.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3167)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 218, 317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 651)
[M::mem_pestat] mean and std.dev: (243.06, 120.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 818)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (461, 997, 1369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3185)
[M::mem_pestat] mean and std.dev: (928.94, 601.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4093)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 404, 1299)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3483)
[M::mem_pestat] mean and std.dev: (776.64, 812.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4575)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704770 sequences (100000145 bp) in 2.180 CPU sec, 2.184 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (73, 280455, 60, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 504, 1462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3982)
[M::mem_pestat] mean and std.dev: (846.29, 884.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5242)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 220, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 661)
[M::mem_pestat] mean and std.dev: (246.32, 123.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 831)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (397, 653, 1313)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3145)
[M::mem_pestat] mean and std.dev: (770.74, 572.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4061)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 434, 979)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2487)
[M::mem_pestat] mean and std.dev: (587.80, 517.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3241)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 280921, 44, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 483, 1596)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4418)
[M::mem_pestat] mean and std.dev: (896.09, 972.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5829)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 218, 316)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 648)
[M::mem_pestat] mean and std.dev: (242.84, 120.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 814)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (458, 1096, 1672)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4100)
[M::mem_pestat] mean and std.dev: (1014.61, 737.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5314)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (242, 396, 1049)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2663)
[M::mem_pestat] mean and std.dev: (521.84, 497.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3470)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 705620 reads in 313.721 CPU sec, 10.006 real sec
[M::mem_process_seqs] Processed 705252 reads in 253.726 CPU sec, 8.138 real sec
sorting block 84, #reads = 1064542 mem = 536879568 peak = 1121685504
[M::process] read 182130 sequences (25805952 bp) in 0.974 CPU sec, 1.005 real sec...
[M::mem_process_seqs] Processed 705896 reads in 288.459 CPU sec, 9.249 real sec
sorting block 85, #reads = 1064756 mem = 536877398 peak = 1121685504
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 280335, 43, 82)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 371, 982)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2536)
[M::mem_pestat] mean and std.dev: (584.27, 583.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3313)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 221, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 661)
[M::mem_pestat] mean and std.dev: (246.21, 122.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 831)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (450, 1179, 2658)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7074)
[M::mem_pestat] mean and std.dev: (1772.28, 1800.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9282)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (251, 440, 1910)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5228)
[M::mem_pestat] mean and std.dev: (1128.90, 1204.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6887)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (15, 72466, 21, 24)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (260, 385, 628)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1364)
[M::mem_pestat] mean and std.dev: (384.07, 218.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1732)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 219, 318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 654)
[M::mem_pestat] mean and std.dev: (244.08, 121.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 822)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (466, 746, 1375)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3193)
[M::mem_pestat] mean and std.dev: (608.18, 353.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4102)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 509, 2080)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5796)
[M::mem_pestat] mean and std.dev: (870.17, 918.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7654)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704770 reads in 154.982 CPU sec, 5.029 real sec
[M::mem_process_seqs] Processed 182130 reads in 70.504 CPU sec, 2.287 real sec
sorting block 86, #reads = 1062341 mem = 536883073 peak = 1121685504
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000c06f2
  features: bfebfbff 7ffefbff
  extended: f3bfb7ef fb417ffe
  amd bits: 2c100800 00000121
     brand: INTEL(R) XEON(R) PLATINUM 8559C
threads: 31
algo: bwa-mem
license: sentieon:klib=31
reads: 92091272
overall: 71035342848 mem 16954.648 user 303.968 sys 566.886 real
[main] Version: 0.7.17-r1188
[main] CMD: /opt/conda/share/sentieon-202308.03-3/libexec/bwa mem -K 100000000 -Y -R @RG\tID:A23MHWWLT4.1136_3WJ-T1-TDNA-1_A23MHWWLT4_1.L007\tPU:L007\tSM:1136_3WJ-T1-TDNA-1_A23MHWWLT4_1\tLB:1136_3WJ-T1-TDNA-1_A23MHWWLT4_1\tDS:s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta\tPL:ILLUMINA -t 31 ./BWAIndex/Homo_sapiens_assembly38.fasta.64 1136_3WJ-T1-TDNA-1_A23MHWWLT4_1_R1.fastq.gz 1136_3WJ-T1-TDNA-1_A23MHWWLT4_1_R2.fastq.gz
[main] Real time: 566.927 sec; CPU: 17258.619 sec
sorting block 87, #reads = 74753 mem = 38380607 peak = 1121685504
uniq header count 1
merging 88 blocks
sw version: sentieon-genomics-202308.03
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000c06f2
  features: bfebfbff 7ffefbff
  extended: f3bfb7ef fb417ffe
  amd bits: 2c100800 00000121
     brand: INTEL(R) XEON(R) PLATINUM 8559C
threads: 31 max 192
algo: util-sort
license: sentieon:util=1
output file size: 5487391594
output reads: 92973376
bam_mem_sort: 88 calls 50.980 user 1.199 sys 52.404 real
bam_write: 88 calls 32.431 user 2.323 sys 40.798 real
execute: 1 calls 32.789 user 1.206 sys 608.697 real
merge_files: 1 calls 32.761 user 1.176 sys 41.707 real
parse_chunk: 1394 calls 78.621 user 18.060 sys 99.823 real
read_chunk: 3778 calls 42.626 user 27.760 sys 528.319 real
sort_block: 1 calls 27.146 user 27.244 sys 508.460 real
write_chunk: 2382 calls 32.399 user 0.870 sys 40.716 real
overall: 3328823296 mem 1621.752 user 66.617 sys 608.722 real
ls: cannot access '*.cram': No such file or directory