This software is licensed to bgold@natera.com by Sentieon Inc.
cmdline: /opt/conda/share/sentieon-202308.03-3/libexec/util sort -r Homo_sapiens_assembly38.fasta -t 31 -o 1136_8DV-T1-TDNA-1_A23MHWWLT4_1.bam --sam2bam -
This software is licensed to bgold@natera.com by Sentieon Inc.
version: sentieon-genomics-202308.03
[M::bwa_idx_load_from_disk] read 3171 ALT contigs
[M::main_mem] bwa index loaded in 2770.359 CPU sec, 113.006 real sec
[M::process] read 724816 sequences (100000047 bp) in 1.349 CPU sec, 1.356 real sec...
[M::process] read 723422 sequences (100000151 bp) in 1.954 CPU sec, 1.982 real sec...
[M::process] read 722384 sequences (100000083 bp) in 2.043 CPU sec, 2.064 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (19, 292064, 29, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 219, 261)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 479)
[M::mem_pestat] mean and std.dev: (215.22, 91.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 588)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 188, 285)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 591)
[M::mem_pestat] mean and std.dev: (217.01, 112.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 744)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (227, 553, 1292)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3422)
[M::mem_pestat] mean and std.dev: (738.69, 697.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4487)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 255, 709)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1743)
[M::mem_pestat] mean and std.dev: (389.42, 333.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2260)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720992 sequences (100000034 bp) in 1.781 CPU sec, 1.823 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (19, 291121, 12, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 269, 1417)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3893)
[M::mem_pestat] mean and std.dev: (943.83, 1236.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5890)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 191, 291)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 607)
[M::mem_pestat] mean and std.dev: (220.50, 115.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 765)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (440, 668, 2706)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7238)
[M::mem_pestat] mean and std.dev: (987.36, 998.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9504)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 330, 1524)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4196)
[M::mem_pestat] mean and std.dev: (1090.16, 1337.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6439)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 291124, 10, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 334, 467)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1023)
[M::mem_pestat] mean and std.dev: (287.05, 145.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1301)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 192, 292)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 608)
[M::mem_pestat] mean and std.dev: (221.70, 115.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 766)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (514, 1664, 1664)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3964)
[M::mem_pestat] mean and std.dev: (1308.30, 737.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5114)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (300, 550, 1054)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2562)
[M::mem_pestat] mean and std.dev: (760.20, 592.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3316)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 724816 reads in 378.656 CPU sec, 12.388 real sec
[M::mem_process_seqs] Processed 723422 reads in 240.807 CPU sec, 7.901 real sec
[M::mem_process_seqs] Processed 722384 reads in 263.324 CPU sec, 8.669 real sec
sorting block 0, #reads = 1093046 mem = 536878706 peak = 554971136
[M::process] read 720292 sequences (100000011 bp) in 2.278 CPU sec, 2.647 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 291013, 25, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (230, 346, 635)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1445)
[M::mem_pestat] mean and std.dev: (394.39, 250.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1850)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 195, 297)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 621)
[M::mem_pestat] mean and std.dev: (225.48, 118.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 783)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (694, 1784, 1964)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4504)
[M::mem_pestat] mean and std.dev: (1332.52, 772.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5774)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 404, 5799)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 17015)
[M::mem_pestat] mean and std.dev: (1855.21, 2339.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 22623)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 1, #reads = 1092194 mem = 536877767 peak = 844378112
[M::process] read 719768 sequences (100000087 bp) in 2.313 CPU sec, 2.481 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 290526, 9, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (124, 140, 686)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1810)
[M::mem_pestat] mean and std.dev: (280.30, 333.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2372)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 196, 298)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 622)
[M::mem_pestat] mean and std.dev: (225.87, 118.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 784)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 260, 619)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1479)
[M::mem_pestat] mean and std.dev: (334.78, 236.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1909)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 718750 sequences (100000254 bp) in 1.810 CPU sec, 1.822 real sec...
[M::mem_process_seqs] Processed 720992 reads in 230.118 CPU sec, 7.436 real sec
[M::mem_process_seqs] Processed 720292 reads in 147.259 CPU sec, 4.743 real sec
sorting block 2, #reads = 1090480 mem = 536882717 peak = 844378112
[M::process] read 718902 sequences (100000023 bp) in 2.170 CPU sec, 2.475 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 289824, 15, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (142, 264, 1190)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3286)
[M::mem_pestat] mean and std.dev: (579.84, 666.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4334)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 198, 302)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 634)
[M::mem_pestat] mean and std.dev: (228.40, 120.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 800)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (303, 919, 2022)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5460)
[M::mem_pestat] mean and std.dev: (735.67, 642.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7179)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 370, 1324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3626)
[M::mem_pestat] mean and std.dev: (603.52, 590.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4777)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 719768 reads in 126.399 CPU sec, 4.298 real sec
[M::process] read 718868 sequences (100000245 bp) in 2.369 CPU sec, 2.731 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 289914, 32, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 302, 559)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1273)
[M::mem_pestat] mean and std.dev: (299.00, 148.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1630)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 199, 304)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 638)
[M::mem_pestat] mean and std.dev: (230.06, 121.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 805)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (445, 1298, 4357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12181)
[M::mem_pestat] mean and std.dev: (2076.34, 1944.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 16093)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (232, 263, 355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 601)
[M::mem_pestat] mean and std.dev: (250.56, 69.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 724)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 719500 sequences (100000239 bp) in 2.053 CPU sec, 2.065 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 290288, 16, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 312, 1024)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2750)
[M::mem_pestat] mean and std.dev: (519.18, 526.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3613)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 199, 303)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 635)
[M::mem_pestat] mean and std.dev: (229.37, 120.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 801)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (233, 1632, 2878)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8168)
[M::mem_pestat] mean and std.dev: (1897.80, 2149.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10813)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 360, 412)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 910)
[M::mem_pestat] mean and std.dev: (309.41, 176.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1159)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 289744, 13, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 447, 1218)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3330)
[M::mem_pestat] mean and std.dev: (706.48, 798.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4386)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 199, 304)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 638)
[M::mem_pestat] mean and std.dev: (229.88, 121.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 805)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (304, 807, 1329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3379)
[M::mem_pestat] mean and std.dev: (861.58, 824.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4404)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 506, 1267)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3383)
[M::mem_pestat] mean and std.dev: (609.61, 503.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4441)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 718750 reads in 352.458 CPU sec, 11.491 real sec
sorting block 3, #reads = 1089429 mem = 536882767 peak = 844378112
[M::mem_process_seqs] Processed 718902 reads in 245.347 CPU sec, 7.973 real sec
[M::mem_process_seqs] Processed 718868 reads in 267.138 CPU sec, 8.791 real sec
sorting block 4, #reads = 1091390 mem = 536878934 peak = 844378112
[M::process] read 717904 sequences (100000136 bp) in 2.873 CPU sec, 3.199 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 290268, 10, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 411, 965)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2447)
[M::mem_pestat] mean and std.dev: (533.37, 508.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3188)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 197, 299)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 625)
[M::mem_pestat] mean and std.dev: (227.18, 119.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 788)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (371, 2380, 2655)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7223)
[M::mem_pestat] mean and std.dev: (1816.40, 1870.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9507)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 359, 467)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1067)
[M::mem_pestat] mean and std.dev: (342.53, 206.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1367)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 717650 sequences (100000225 bp) in 2.540 CPU sec, 2.853 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 289760, 26, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 367, 910)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2428)
[M::mem_pestat] mean and std.dev: (472.73, 470.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3187)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 201, 307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 645)
[M::mem_pestat] mean and std.dev: (232.02, 123.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 814)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (359, 511, 1777)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4613)
[M::mem_pestat] mean and std.dev: (876.64, 820.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6031)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (233, 285, 850)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2084)
[M::mem_pestat] mean and std.dev: (466.56, 439.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2701)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 719500 reads in 232.070 CPU sec, 7.731 real sec
sorting block 5, #reads = 1088417 mem = 536876253 peak = 844378112
[M::mem_process_seqs] Processed 717904 reads in 150.077 CPU sec, 4.890 real sec
[M::process] read 717540 sequences (100000297 bp) in 2.477 CPU sec, 2.700 real sec...
sorting block 6, #reads = 1090202 mem = 536877001 peak = 844378112
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 289185, 27, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (296, 412, 1875)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5033)
[M::mem_pestat] mean and std.dev: (1027.11, 1372.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6612)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 200, 305)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 639)
[M::mem_pestat] mean and std.dev: (230.91, 121.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 806)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (292, 398, 1470)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3826)
[M::mem_pestat] mean and std.dev: (726.79, 767.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5004)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 451, 1528)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4208)
[M::mem_pestat] mean and std.dev: (735.26, 768.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5548)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 717302 sequences (100000062 bp) in 2.873 CPU sec, 3.201 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 290054, 27, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 233, 413)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 883)
[M::mem_pestat] mean and std.dev: (237.87, 118.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1118)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 200, 303)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 633)
[M::mem_pestat] mean and std.dev: (229.78, 120.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 798)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (626, 916, 2084)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5000)
[M::mem_pestat] mean and std.dev: (1088.13, 896.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6458)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 362, 1574)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4402)
[M::mem_pestat] mean and std.dev: (977.77, 1239.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5935)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 717156 sequences (100000275 bp) in 1.845 CPU sec, 1.863 real sec...
[M::mem_process_seqs] Processed 717650 reads in 234.855 CPU sec, 7.537 real sec
[M::mem_process_seqs] Processed 717540 reads in 153.317 CPU sec, 4.895 real sec
sorting block 7, #reads = 1088556 mem = 536876947 peak = 844378112
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 289330, 20, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 252, 385)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 811)
[M::mem_pestat] mean and std.dev: (243.81, 121.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1024)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 200, 303)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 633)
[M::mem_pestat] mean and std.dev: (229.87, 119.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 798)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (341, 416, 571)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1031)
[M::mem_pestat] mean and std.dev: (369.41, 141.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1261)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 215, 510)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1194)
[M::mem_pestat] mean and std.dev: (313.14, 262.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1536)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 718122 sequences (100000214 bp) in 3.213 CPU sec, 3.694 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 289784, 23, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 255, 568)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1404)
[M::mem_pestat] mean and std.dev: (337.32, 303.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1822)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 201, 304)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 636)
[M::mem_pestat] mean and std.dev: (230.60, 120.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 802)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (652, 652, 916)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (124, 1444)
[M::mem_pestat] mean and std.dev: (630.42, 279.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1750)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (259, 356, 1344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3514)
[M::mem_pestat] mean and std.dev: (654.65, 587.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4599)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 717494 sequences (100000209 bp) in 2.007 CPU sec, 2.019 real sec...
[M::mem_process_seqs] Processed 717302 reads in 232.876 CPU sec, 7.489 real sec
[M::mem_process_seqs] Processed 717156 reads in 154.536 CPU sec, 5.226 real sec
sorting block 8, #reads = 1089305 mem = 536878136 peak = 844378112
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 290436, 12, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 300, 1683)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4689)
[M::mem_pestat] mean and std.dev: (879.55, 997.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6192)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 199, 301)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 629)
[M::mem_pestat] mean and std.dev: (228.14, 118.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 793)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (124, 456, 634)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1654)
[M::mem_pestat] mean and std.dev: (250.90, 215.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2164)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (310, 332, 699)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1477)
[M::mem_pestat] mean and std.dev: (390.93, 237.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1866)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 717546 sequences (100000010 bp) in 2.974 CPU sec, 3.374 real sec...
[M::process] read 718258 sequences (100000154 bp) in 2.082 CPU sec, 2.092 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 289069, 24, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 259, 577)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1383)
[M::mem_pestat] mean and std.dev: (386.57, 333.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1786)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 199, 302)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 630)
[M::mem_pestat] mean and std.dev: (229.02, 119.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 794)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (322, 1365, 1684)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4408)
[M::mem_pestat] mean and std.dev: (1300.74, 1155.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5923)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 384, 2015)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5727)
[M::mem_pestat] mean and std.dev: (1021.03, 1110.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7583)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 718122 reads in 233.293 CPU sec, 7.789 real sec
sorting block 9, #reads = 1089715 mem = 536881364 peak = 844378112
[M::mem_process_seqs] Processed 717494 reads in 155.312 CPU sec, 5.067 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 289496, 21, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (303, 460, 1462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3780)
[M::mem_pestat] mean and std.dev: (922.70, 875.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4939)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 200, 304)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 636)
[M::mem_pestat] mean and std.dev: (230.07, 120.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 802)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (112, 667, 1704)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4888)
[M::mem_pestat] mean and std.dev: (1062.76, 1198.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6480)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 238, 664)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1656)
[M::mem_pestat] mean and std.dev: (413.10, 397.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2152)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 10, #reads = 1087857 mem = 536880354 peak = 844378112
[M::process] read 717456 sequences (100000013 bp) in 2.980 CPU sec, 3.504 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 289353, 22, 17)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 273, 1287)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3495)
[M::mem_pestat] mean and std.dev: (722.81, 796.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4599)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 199, 303)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 635)
[M::mem_pestat] mean and std.dev: (229.72, 121.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 801)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (263, 632, 2514)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7016)
[M::mem_pestat] mean and std.dev: (1050.41, 1042.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9267)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 431, 1252)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3390)
[M::mem_pestat] mean and std.dev: (609.06, 549.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4459)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722640 sequences (100000065 bp) in 2.005 CPU sec, 2.017 real sec...
[M::mem_process_seqs] Processed 717546 reads in 240.884 CPU sec, 7.878 real sec
[M::mem_process_seqs] Processed 718258 reads in 156.015 CPU sec, 4.983 real sec
sorting block 11, #reads = 1088151 mem = 536888312 peak = 844378112
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 289285, 14, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 249, 1314)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3614)
[M::mem_pestat] mean and std.dev: (618.06, 634.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4764)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 200, 307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 645)
[M::mem_pestat] mean and std.dev: (231.70, 122.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 814)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 698, 2402)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6800)
[M::mem_pestat] mean and std.dev: (1278.36, 1190.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8999)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 386, 632)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1480)
[M::mem_pestat] mean and std.dev: (355.73, 206.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1904)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722792 sequences (100000170 bp) in 3.154 CPU sec, 3.486 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 291736, 21, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 453, 1565)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4263)
[M::mem_pestat] mean and std.dev: (699.93, 861.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5612)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 192, 290)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 602)
[M::mem_pestat] mean and std.dev: (220.55, 114.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 758)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 383, 1412)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3888)
[M::mem_pestat] mean and std.dev: (791.38, 931.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5126)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 356, 1193)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3259)
[M::mem_pestat] mean and std.dev: (557.15, 605.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4292)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 721616 sequences (100000075 bp) in 2.349 CPU sec, 2.365 real sec...
[M::mem_process_seqs] Processed 717456 reads in 238.694 CPU sec, 7.950 real sec
[M::mem_process_seqs] Processed 722640 reads in 151.156 CPU sec, 5.126 real sec
sorting block 12, #reads = 1087402 mem = 536877081 peak = 844378112
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 291521, 16, 19)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 332, 947)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2417)
[M::mem_pestat] mean and std.dev: (488.38, 536.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3152)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 192, 292)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 608)
[M::mem_pestat] mean and std.dev: (221.17, 115.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 766)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 570, 1555)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4243)
[M::mem_pestat] mean and std.dev: (1141.31, 1370.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6622)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (330, 712, 3397)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9531)
[M::mem_pestat] mean and std.dev: (1621.32, 1525.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12598)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720474 sequences (100000186 bp) in 3.091 CPU sec, 3.420 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 290990, 15, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (131, 261, 1545)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4373)
[M::mem_pestat] mean and std.dev: (859.85, 1138.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5787)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 194, 294)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 612)
[M::mem_pestat] mean and std.dev: (223.39, 116.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 771)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 420, 906)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2302)
[M::mem_pestat] mean and std.dev: (427.38, 416.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3000)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 293, 585)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1383)
[M::mem_pestat] mean and std.dev: (343.03, 263.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1782)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720146 sequences (100000223 bp) in 1.971 CPU sec, 1.980 real sec...
[M::mem_process_seqs] Processed 722792 reads in 227.840 CPU sec, 7.375 real sec
sorting block 13, #reads = 1090711 mem = 536876607 peak = 844378112
[M::mem_process_seqs] Processed 721616 reads in 141.939 CPU sec, 4.528 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 290506, 20, 21)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 464, 1617)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4483)
[M::mem_pestat] mean and std.dev: (762.34, 779.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5916)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 195, 298)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 622)
[M::mem_pestat] mean and std.dev: (225.39, 117.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 784)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (8, 128, 629)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1871)
[M::mem_pestat] mean and std.dev: (332.10, 460.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2492)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 234, 708)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1694)
[M::mem_pestat] mean and std.dev: (403.57, 328.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2187)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 14, #reads = 1093400 mem = 536880783 peak = 844378112
[M::process] read 719948 sequences (100000063 bp) in 3.341 CPU sec, 3.705 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 290641, 12, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 238, 409)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 927)
[M::mem_pestat] mean and std.dev: (222.75, 106.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1186)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 197, 300)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 628)
[M::mem_pestat] mean and std.dev: (226.88, 119.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 792)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (395, 806, 1760)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4490)
[M::mem_pestat] mean and std.dev: (911.91, 695.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5855)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (320, 355, 824)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1832)
[M::mem_pestat] mean and std.dev: (447.82, 303.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2336)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 719552 sequences (100000097 bp) in 2.155 CPU sec, 2.165 real sec...
[M::mem_process_seqs] Processed 720474 reads in 223.706 CPU sec, 7.190 real sec
[M::mem_process_seqs] Processed 720146 reads in 143.595 CPU sec, 4.659 real sec
sorting block 15, #reads = 1092472 mem = 536881509 peak = 844378112
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (22, 290453, 14, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 258, 554)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1332)
[M::mem_pestat] mean and std.dev: (350.71, 267.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1721)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 197, 301)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 631)
[M::mem_pestat] mean and std.dev: (227.58, 119.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 796)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (629, 1591, 1842)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4268)
[M::mem_pestat] mean and std.dev: (1026.36, 565.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5481)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 246, 724)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1876)
[M::mem_pestat] mean and std.dev: (302.88, 258.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2452)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 719434 sequences (100000105 bp) in 3.115 CPU sec, 3.509 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (21, 290806, 30, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 169, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 696)
[M::mem_pestat] mean and std.dev: (197.63, 82.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 878)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 197, 302)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 634)
[M::mem_pestat] mean and std.dev: (228.55, 120.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 800)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (115, 553, 1171)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3283)
[M::mem_pestat] mean and std.dev: (610.31, 595.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4339)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 267, 912)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2410)
[M::mem_pestat] mean and std.dev: (536.89, 563.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3159)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 718422 sequences (100000013 bp) in 1.868 CPU sec, 1.893 real sec...
[M::mem_process_seqs] Processed 719948 reads in 226.315 CPU sec, 7.328 real sec
[M::mem_process_seqs] Processed 719552 reads in 144.406 CPU sec, 4.630 real sec
sorting block 16, #reads = 1091862 mem = 536878136 peak = 844378112
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 290218, 30, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (242, 626, 864)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2108)
[M::mem_pestat] mean and std.dev: (512.48, 277.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2730)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 198, 304)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 640)
[M::mem_pestat] mean and std.dev: (229.60, 121.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 808)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 286, 1465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4017)
[M::mem_pestat] mean and std.dev: (916.93, 1085.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5293)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 305, 436)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 932)
[M::mem_pestat] mean and std.dev: (251.61, 107.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1180)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 718770 sequences (100000024 bp) in 3.277 CPU sec, 3.713 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 290276, 17, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 623, 2743)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7925)
[M::mem_pestat] mean and std.dev: (1512.52, 1807.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10516)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 199, 306)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 644)
[M::mem_pestat] mean and std.dev: (231.15, 122.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 813)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (82, 82, 456)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1204)
[M::mem_pestat] mean and std.dev: (210.12, 224.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1578)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 309, 501)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1183)
[M::mem_pestat] mean and std.dev: (263.58, 144.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1524)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 717778 sequences (100000114 bp) in 2.001 CPU sec, 2.057 real sec...
[M::mem_process_seqs] Processed 719434 reads in 228.873 CPU sec, 7.461 real sec
sorting block 17, #reads = 1091247 mem = 536879941 peak = 844378112
[M::mem_process_seqs] Processed 718422 reads in 145.167 CPU sec, 4.645 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 290800, 12, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 286, 4407)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12909)
[M::mem_pestat] mean and std.dev: (2310.05, 3254.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17160)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 199, 305)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 641)
[M::mem_pestat] mean and std.dev: (230.11, 121.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 809)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (35, 583, 1919)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5687)
[M::mem_pestat] mean and std.dev: (928.83, 924.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7571)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 294, 472)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 976)
[M::mem_pestat] mean and std.dev: (339.10, 191.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1228)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 18, #reads = 1090511 mem = 536878036 peak = 844378112
[M::process] read 718634 sequences (100000099 bp) in 2.877 CPU sec, 3.282 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 290358, 18, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 377, 1531)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4191)
[M::mem_pestat] mean and std.dev: (599.30, 546.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5521)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 201, 305)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 639)
[M::mem_pestat] mean and std.dev: (230.89, 121.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 806)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 345, 456)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1028)
[M::mem_pestat] mean and std.dev: (260.87, 137.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1314)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (265, 410, 938)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2284)
[M::mem_pestat] mean and std.dev: (576.37, 471.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2957)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 717454 sequences (100000294 bp) in 2.036 CPU sec, 2.054 real sec...
[M::mem_process_seqs] Processed 718770 reads in 228.827 CPU sec, 7.472 real sec
[M::mem_process_seqs] Processed 717778 reads in 145.815 CPU sec, 4.748 real sec
sorting block 19, #reads = 1090059 mem = 536881363 peak = 844378112
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 289493, 23, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 225, 559)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1343)
[M::mem_pestat] mean and std.dev: (329.46, 312.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1735)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 199, 305)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 641)
[M::mem_pestat] mean and std.dev: (230.58, 122.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 809)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (449, 838, 1274)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2924)
[M::mem_pestat] mean and std.dev: (568.50, 380.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3749)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 321, 375)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 679)
[M::mem_pestat] mean and std.dev: (275.88, 81.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 831)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 717852 sequences (100000219 bp) in 3.110 CPU sec, 3.495 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 289079, 21, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 377, 669)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1623)
[M::mem_pestat] mean and std.dev: (441.83, 338.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2100)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 201, 307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 645)
[M::mem_pestat] mean and std.dev: (231.93, 122.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 814)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 495, 644)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1526)
[M::mem_pestat] mean and std.dev: (435.38, 249.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1967)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 303, 576)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1350)
[M::mem_pestat] mean and std.dev: (312.44, 243.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1737)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 718244 sequences (100000116 bp) in 2.191 CPU sec, 2.208 real sec...
[M::mem_process_seqs] Processed 718634 reads in 227.872 CPU sec, 7.419 real sec
[M::mem_process_seqs] Processed 717454 reads in 146.101 CPU sec, 4.674 real sec
sorting block 20, #reads = 1090106 mem = 536879631 peak = 844378112
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 289678, 13, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (237, 379, 1276)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3354)
[M::mem_pestat] mean and std.dev: (532.72, 469.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4393)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 200, 304)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 636)
[M::mem_pestat] mean and std.dev: (230.41, 121.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 802)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 751, 2941)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8503)
[M::mem_pestat] mean and std.dev: (1256.31, 1414.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11284)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 290, 592)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1430)
[M::mem_pestat] mean and std.dev: (356.31, 248.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1849)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 717726 sequences (100000300 bp) in 3.086 CPU sec, 3.554 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 290055, 17, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 245, 404)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 874)
[M::mem_pestat] mean and std.dev: (262.86, 151.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1109)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 199, 301)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 629)
[M::mem_pestat] mean and std.dev: (228.70, 119.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 793)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 325, 925)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2385)
[M::mem_pestat] mean and std.dev: (414.44, 353.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3115)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 434, 687)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1657)
[M::mem_pestat] mean and std.dev: (439.98, 318.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2142)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 717664 sequences (100000181 bp) in 1.841 CPU sec, 1.962 real sec...
[M::mem_process_seqs] Processed 717852 reads in 226.621 CPU sec, 7.383 real sec
sorting block 21, #reads = 1089617 mem = 536877551 peak = 844378112
[M::mem_process_seqs] Processed 718244 reads in 147.731 CPU sec, 4.754 real sec
sorting block 22, #reads = 1089951 mem = 536881969 peak = 844378112
[M::process] read 717922 sequences (100000146 bp) in 3.221 CPU sec, 3.617 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 289108, 12, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (119, 295, 543)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1391)
[M::mem_pestat] mean and std.dev: (237.93, 174.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1815)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 199, 302)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 630)
[M::mem_pestat] mean and std.dev: (229.24, 120.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 794)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (440, 568, 2982)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8066)
[M::mem_pestat] mean and std.dev: (1168.82, 1430.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10608)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 297, 752)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1894)
[M::mem_pestat] mean and std.dev: (449.56, 413.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2465)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 717664 reads in 127.989 CPU sec, 4.071 real sec
[M::process] read 718052 sequences (100000156 bp) in 2.367 CPU sec, 2.446 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 289714, 15, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 199, 439)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 921)
[M::mem_pestat] mean and std.dev: (264.00, 154.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1162)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 200, 303)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 633)
[M::mem_pestat] mean and std.dev: (229.61, 119.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 798)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (123, 434, 780)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2094)
[M::mem_pestat] mean and std.dev: (381.00, 315.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2751)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 538, 1709)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4699)
[M::mem_pestat] mean and std.dev: (803.16, 861.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6194)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 289460, 10, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 251, 1160)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3158)
[M::mem_pestat] mean and std.dev: (494.19, 731.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4157)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 200, 301)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 627)
[M::mem_pestat] mean and std.dev: (228.93, 119.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 790)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (738, 1235, 3564)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9216)
[M::mem_pestat] mean and std.dev: (1854.00, 1646.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12042)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (367, 464, 1187)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2827)
[M::mem_pestat] mean and std.dev: (669.94, 542.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3647)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 717726 reads in 344.449 CPU sec, 11.123 real sec
[M::process] read 718214 sequences (100000294 bp) in 2.202 CPU sec, 2.223 real sec...
sorting block 23, #reads = 1088135 mem = 536880166 peak = 844378112
[M::mem_process_seqs] Processed 717922 reads in 169.480 CPU sec, 5.674 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 290104, 18, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 260, 674)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1658)
[M::mem_pestat] mean and std.dev: (349.50, 248.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2150)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 199, 303)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 633)
[M::mem_pestat] mean and std.dev: (229.73, 120.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 798)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (306, 688, 2911)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8121)
[M::mem_pestat] mean and std.dev: (1886.67, 2489.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11845)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 305, 1030)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2740)
[M::mem_pestat] mean and std.dev: (493.77, 459.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3595)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 24, #reads = 1087936 mem = 536880303 peak = 844378112
[M::process] read 719460 sequences (100000044 bp) in 3.183 CPU sec, 3.526 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23, 289282, 25, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 291, 1173)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3173)
[M::mem_pestat] mean and std.dev: (583.33, 666.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4173)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 199, 304)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 638)
[M::mem_pestat] mean and std.dev: (230.20, 122.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 805)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 424, 2175)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6221)
[M::mem_pestat] mean and std.dev: (993.67, 1122.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8244)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 394, 970)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2512)
[M::mem_pestat] mean and std.dev: (514.11, 444.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3283)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 718052 reads in 224.020 CPU sec, 7.529 real sec
[M::mem_process_seqs] Processed 718214 reads in 149.085 CPU sec, 4.789 real sec
[M::process] read 723262 sequences (100000142 bp) in 2.387 CPU sec, 2.562 real sec...
sorting block 25, #reads = 1089650 mem = 536876583 peak = 844378112
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 289902, 28, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 243, 1669)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4679)
[M::mem_pestat] mean and std.dev: (701.70, 813.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6184)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 197, 300)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 628)
[M::mem_pestat] mean and std.dev: (227.32, 119.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 792)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (526, 941, 1506)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3466)
[M::mem_pestat] mean and std.dev: (969.96, 680.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4446)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 240, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 781)
[M::mem_pestat] mean and std.dev: (248.84, 136.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 989)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 721784 sequences (100000297 bp) in 2.988 CPU sec, 3.410 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 291589, 28, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 545, 1290)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3472)
[M::mem_pestat] mean and std.dev: (546.57, 474.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4563)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 192, 290)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 604)
[M::mem_pestat] mean and std.dev: (220.24, 114.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 761)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 633, 1068)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2822)
[M::mem_pestat] mean and std.dev: (549.58, 581.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3699)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 331, 670)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1564)
[M::mem_pestat] mean and std.dev: (423.52, 351.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2011)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720438 sequences (100000077 bp) in 2.102 CPU sec, 2.106 real sec...
[M::mem_process_seqs] Processed 719460 reads in 230.930 CPU sec, 7.428 real sec
[M::mem_process_seqs] Processed 723262 reads in 147.464 CPU sec, 4.718 real sec
sorting block 26, #reads = 1087706 mem = 536885279 peak = 844378112
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 291119, 22, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 252, 794)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2068)
[M::mem_pestat] mean and std.dev: (408.65, 456.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2705)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 194, 295)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 615)
[M::mem_pestat] mean and std.dev: (223.61, 116.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 775)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 270, 842)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2224)
[M::mem_pestat] mean and std.dev: (466.25, 527.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2915)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 270, 885)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2351)
[M::mem_pestat] mean and std.dev: (471.77, 505.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3084)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720344 sequences (100000132 bp) in 3.125 CPU sec, 3.497 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 290852, 17, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 237, 642)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1620)
[M::mem_pestat] mean and std.dev: (404.74, 439.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2163)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 196, 298)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 622)
[M::mem_pestat] mean and std.dev: (225.51, 117.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 784)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (11, 60, 1092)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3254)
[M::mem_pestat] mean and std.dev: (293.67, 415.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4335)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 349, 536)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1220)
[M::mem_pestat] mean and std.dev: (357.37, 227.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1562)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 719386 sequences (100000049 bp) in 2.173 CPU sec, 2.209 real sec...
[M::mem_process_seqs] Processed 721784 reads in 222.879 CPU sec, 7.188 real sec
sorting block 27, #reads = 1094469 mem = 536882251 peak = 844378112
[M::mem_process_seqs] Processed 720438 reads in 146.085 CPU sec, 4.780 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 290269, 16, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 260, 427)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 941)
[M::mem_pestat] mean and std.dev: (278.00, 172.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1198)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 196, 299)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 625)
[M::mem_pestat] mean and std.dev: (226.27, 118.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 788)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (375, 1480, 4083)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 11499)
[M::mem_pestat] mean and std.dev: (2071.12, 2007.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 15207)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 256, 762)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1920)
[M::mem_pestat] mean and std.dev: (325.68, 223.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2499)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 28, #reads = 1092943 mem = 536882627 peak = 844378112
[M::process] read 719600 sequences (100000001 bp) in 2.771 CPU sec, 3.156 real sec...
[M::process] read 719198 sequences (100000144 bp) in 2.080 CPU sec, 2.107 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 290457, 15, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 243, 437)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 945)
[M::mem_pestat] mean and std.dev: (322.61, 180.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1199)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 198, 301)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 629)
[M::mem_pestat] mean and std.dev: (227.97, 119.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 793)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (462, 633, 1310)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3006)
[M::mem_pestat] mean and std.dev: (696.77, 490.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3854)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 269, 1008)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2686)
[M::mem_pestat] mean and std.dev: (681.32, 660.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3525)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 720344 reads in 231.943 CPU sec, 7.603 real sec
[M::mem_process_seqs] Processed 719386 reads in 150.308 CPU sec, 4.874 real sec
sorting block 29, #reads = 1090899 mem = 536879477 peak = 844378112
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 290359, 30, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (266, 395, 1037)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2579)
[M::mem_pestat] mean and std.dev: (624.40, 526.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3350)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 198, 303)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 637)
[M::mem_pestat] mean and std.dev: (229.03, 121.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 804)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 480, 1198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3294)
[M::mem_pestat] mean and std.dev: (730.00, 653.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4342)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 210, 994)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2628)
[M::mem_pestat] mean and std.dev: (495.36, 522.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3445)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 718258 sequences (100000032 bp) in 3.414 CPU sec, 3.981 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 290216, 15, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 268, 688)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1668)
[M::mem_pestat] mean and std.dev: (369.97, 309.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2158)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 199, 304)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 638)
[M::mem_pestat] mean and std.dev: (229.99, 122.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 805)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (688, 780, 956)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (152, 1492)
[M::mem_pestat] mean and std.dev: (803.91, 186.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1760)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 243, 772)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2022)
[M::mem_pestat] mean and std.dev: (382.26, 313.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2647)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 719600 reads in 221.730 CPU sec, 7.186 real sec
[M::process] read 718034 sequences (100000125 bp) in 2.278 CPU sec, 2.306 real sec...
[M::mem_process_seqs] Processed 719198 reads in 146.674 CPU sec, 4.682 real sec
sorting block 30, #reads = 1091387 mem = 536880809 peak = 844378112
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23, 289977, 16, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (288, 351, 724)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1596)
[M::mem_pestat] mean and std.dev: (486.95, 307.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2032)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 200, 307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 645)
[M::mem_pestat] mean and std.dev: (231.88, 122.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 814)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (244, 267, 941)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2335)
[M::mem_pestat] mean and std.dev: (478.87, 403.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3032)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (248, 351, 1014)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2546)
[M::mem_pestat] mean and std.dev: (488.44, 390.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3312)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 717106 sequences (100000201 bp) in 3.195 CPU sec, 3.497 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 290004, 31, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 260, 442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1006)
[M::mem_pestat] mean and std.dev: (276.16, 180.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1288)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 201, 307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 645)
[M::mem_pestat] mean and std.dev: (231.76, 122.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 814)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 1126, 1397)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3865)
[M::mem_pestat] mean and std.dev: (809.83, 778.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5099)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 229, 537)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1285)
[M::mem_pestat] mean and std.dev: (343.79, 274.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1659)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 716824 sequences (100000064 bp) in 1.858 CPU sec, 1.934 real sec...
[M::mem_process_seqs] Processed 718258 reads in 230.915 CPU sec, 7.451 real sec
sorting block 31, #reads = 1091151 mem = 536881725 peak = 844378112
[M::mem_process_seqs] Processed 718034 reads in 150.164 CPU sec, 4.860 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 289517, 10, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 295, 622)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1440)
[M::mem_pestat] mean and std.dev: (406.27, 247.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1849)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (139, 202, 309)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 649)
[M::mem_pestat] mean and std.dev: (233.16, 123.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 819)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (247, 579, 1159)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2983)
[M::mem_pestat] mean and std.dev: (600.10, 428.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3895)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (265, 431, 1417)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3721)
[M::mem_pestat] mean and std.dev: (736.53, 738.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4873)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 32, #reads = 1090089 mem = 536883786 peak = 844378112
[M::process] read 717308 sequences (100000165 bp) in 2.962 CPU sec, 3.193 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 289021, 17, 24)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 259, 771)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1947)
[M::mem_pestat] mean and std.dev: (351.63, 325.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2535)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 202, 306)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 642)
[M::mem_pestat] mean and std.dev: (231.85, 121.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 810)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (549, 689, 3399)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9099)
[M::mem_pestat] mean and std.dev: (1491.24, 1535.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11949)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (336, 461, 1072)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2544)
[M::mem_pestat] mean and std.dev: (581.58, 442.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3280)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 717422 sequences (100000171 bp) in 2.253 CPU sec, 2.259 real sec...
[M::mem_process_seqs] Processed 717106 reads in 227.158 CPU sec, 7.356 real sec
[M::mem_process_seqs] Processed 716824 reads in 148.037 CPU sec, 4.753 real sec
sorting block 33, #reads = 1091419 mem = 536879235 peak = 844378112
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 289334, 16, 21)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (138, 260, 406)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 942)
[M::mem_pestat] mean and std.dev: (231.94, 121.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1210)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 200, 305)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 639)
[M::mem_pestat] mean and std.dev: (230.75, 121.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 806)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (375, 1478, 1628)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4134)
[M::mem_pestat] mean and std.dev: (1227.62, 944.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5387)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (286, 764, 1340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3448)
[M::mem_pestat] mean and std.dev: (809.68, 711.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4502)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 717670 sequences (100000204 bp) in 3.122 CPU sec, 3.550 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 289656, 22, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 243, 406)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 872)
[M::mem_pestat] mean and std.dev: (311.62, 202.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1122)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 200, 303)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 633)
[M::mem_pestat] mean and std.dev: (229.42, 119.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 798)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (51, 495, 549)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1545)
[M::mem_pestat] mean and std.dev: (298.94, 226.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2043)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (272, 385, 941)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2279)
[M::mem_pestat] mean and std.dev: (468.83, 350.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2948)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 717498 sequences (100000034 bp) in 2.068 CPU sec, 2.072 real sec...
[M::mem_process_seqs] Processed 717308 reads in 228.286 CPU sec, 7.402 real sec
[M::mem_process_seqs] Processed 717422 reads in 148.099 CPU sec, 4.849 real sec
sorting block 34, #reads = 1088565 mem = 536882556 peak = 844378112
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 289591, 23, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (294, 721, 1905)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5127)
[M::mem_pestat] mean and std.dev: (1094.77, 1349.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6738)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 199, 301)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 627)
[M::mem_pestat] mean and std.dev: (228.47, 118.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 790)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (42, 616, 999)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2913)
[M::mem_pestat] mean and std.dev: (609.27, 628.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3870)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (122, 189, 451)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1109)
[M::mem_pestat] mean and std.dev: (248.75, 201.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1438)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 717998 sequences (100000072 bp) in 3.009 CPU sec, 3.352 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 289384, 14, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (239, 338, 972)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2438)
[M::mem_pestat] mean and std.dev: (542.61, 519.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3171)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 199, 301)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 627)
[M::mem_pestat] mean and std.dev: (228.40, 118.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 790)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 781, 1297)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3465)
[M::mem_pestat] mean and std.dev: (717.71, 592.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4549)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 261, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 721)
[M::mem_pestat] mean and std.dev: (247.95, 93.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 899)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 717560 sequences (100000273 bp) in 2.225 CPU sec, 2.231 real sec...
[M::mem_process_seqs] Processed 717670 reads in 228.598 CPU sec, 7.421 real sec
sorting block 35, #reads = 1089271 mem = 536879542 peak = 844378112
[M::mem_process_seqs] Processed 717498 reads in 149.881 CPU sec, 4.789 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 289987, 22, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 406, 579)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1313)
[M::mem_pestat] mean and std.dev: (402.87, 248.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1680)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 199, 301)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 629)
[M::mem_pestat] mean and std.dev: (227.93, 118.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 793)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (236, 443, 921)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2291)
[M::mem_pestat] mean and std.dev: (576.65, 588.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2976)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 564, 1064)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2740)
[M::mem_pestat] mean and std.dev: (564.52, 466.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3578)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 36, #reads = 1087848 mem = 536877439 peak = 844378112
[M::process] read 717474 sequences (100000189 bp) in 3.092 CPU sec, 3.511 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 289749, 15, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 365, 1852)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5138)
[M::mem_pestat] mean and std.dev: (859.96, 864.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6781)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 200, 301)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 627)
[M::mem_pestat] mean and std.dev: (228.39, 118.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 790)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 1334, 2327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6639)
[M::mem_pestat] mean and std.dev: (1272.08, 1412.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8795)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 308, 806)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2070)
[M::mem_pestat] mean and std.dev: (408.09, 324.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2702)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 717656 sequences (100000046 bp) in 2.048 CPU sec, 2.057 real sec...
[M::mem_process_seqs] Processed 717998 reads in 225.683 CPU sec, 7.240 real sec
[M::mem_process_seqs] Processed 717560 reads in 149.442 CPU sec, 4.768 real sec
sorting block 37, #reads = 1089372 mem = 536884401 peak = 844378112
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 290026, 24, 23)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 576, 1826)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5140)
[M::mem_pestat] mean and std.dev: (921.87, 857.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6797)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 200, 303)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 633)
[M::mem_pestat] mean and std.dev: (229.55, 120.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 798)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (508, 621, 1310)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2914)
[M::mem_pestat] mean and std.dev: (902.17, 679.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3716)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 543, 2316)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6558)
[M::mem_pestat] mean and std.dev: (1124.70, 1483.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8679)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 717476 sequences (100000105 bp) in 3.153 CPU sec, 3.523 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 289797, 20, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (138, 223, 626)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1602)
[M::mem_pestat] mean and std.dev: (305.61, 326.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2090)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 199, 304)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 636)
[M::mem_pestat] mean and std.dev: (230.28, 121.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 802)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 410, 1785)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4939)
[M::mem_pestat] mean and std.dev: (927.58, 992.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6516)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 278, 592)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1386)
[M::mem_pestat] mean and std.dev: (344.82, 252.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1783)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 721934 sequences (100000206 bp) in 2.382 CPU sec, 2.404 real sec...
[M::mem_process_seqs] Processed 717474 reads in 230.394 CPU sec, 7.670 real sec
[M::mem_process_seqs] Processed 717656 reads in 150.436 CPU sec, 4.816 real sec
sorting block 38, #reads = 1088565 mem = 536877725 peak = 844378112
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 289951, 21, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (110, 197, 524)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1352)
[M::mem_pestat] mean and std.dev: (355.28, 366.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1821)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 200, 308)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 648)
[M::mem_pestat] mean and std.dev: (232.42, 124.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 818)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (51, 441, 1554)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4560)
[M::mem_pestat] mean and std.dev: (723.52, 832.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6063)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 328, 937)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2361)
[M::mem_pestat] mean and std.dev: (609.22, 580.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3073)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722110 sequences (100000051 bp) in 3.166 CPU sec, 3.543 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 290558, 27, 15)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 235, 689)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1767)
[M::mem_pestat] mean and std.dev: (380.36, 322.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2306)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 193, 294)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 614)
[M::mem_pestat] mean and std.dev: (222.68, 116.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 774)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (336, 525, 1370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3438)
[M::mem_pestat] mean and std.dev: (854.73, 864.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4472)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 241, 769)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1893)
[M::mem_pestat] mean and std.dev: (394.14, 297.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2455)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 721536 sequences (100000030 bp) in 2.001 CPU sec, 2.029 real sec...
[M::mem_process_seqs] Processed 717476 reads in 228.092 CPU sec, 7.356 real sec
sorting block 39, #reads = 1089276 mem = 536879552 peak = 844378112
[M::mem_process_seqs] Processed 721934 reads in 151.403 CPU sec, 4.838 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 290456, 15, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 235, 865)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2251)
[M::mem_pestat] mean and std.dev: (423.43, 334.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2944)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 193, 293)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 611)
[M::mem_pestat] mean and std.dev: (222.27, 115.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 770)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (94, 178, 312)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 748)
[M::mem_pestat] mean and std.dev: (167.08, 148.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 966)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (238, 448, 598)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1318)
[M::mem_pestat] mean and std.dev: (381.61, 203.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1678)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 40, #reads = 1088523 mem = 536886615 peak = 844378112
[M::process] read 720158 sequences (100000121 bp) in 3.125 CPU sec, 3.495 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 290847, 18, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (300, 464, 538)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1014)
[M::mem_pestat] mean and std.dev: (404.19, 185.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1252)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 194, 297)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 621)
[M::mem_pestat] mean and std.dev: (224.51, 118.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 783)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 237, 1294)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3476)
[M::mem_pestat] mean and std.dev: (658.06, 866.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4567)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 366, 536)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1184)
[M::mem_pestat] mean and std.dev: (379.25, 229.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1508)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 722110 reads in 217.010 CPU sec, 7.005 real sec
[M::process] read 719482 sequences (100000208 bp) in 2.462 CPU sec, 2.556 real sec...
[M::mem_process_seqs] Processed 721536 reads in 144.052 CPU sec, 4.796 real sec
sorting block 41, #reads = 1092825 mem = 536879655 peak = 844378112
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (22, 290609, 18, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (144, 332, 965)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2607)
[M::mem_pestat] mean and std.dev: (456.89, 420.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3428)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 196, 299)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 625)
[M::mem_pestat] mean and std.dev: (226.43, 118.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 788)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 427, 732)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1812)
[M::mem_pestat] mean and std.dev: (383.00, 270.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2352)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 312, 1271)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3389)
[M::mem_pestat] mean and std.dev: (633.26, 641.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4448)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 719150 sequences (100000133 bp) in 3.088 CPU sec, 3.413 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 290931, 23, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 301, 573)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1387)
[M::mem_pestat] mean and std.dev: (307.53, 179.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1794)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 197, 300)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 628)
[M::mem_pestat] mean and std.dev: (227.53, 119.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 792)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (126, 274, 2541)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7371)
[M::mem_pestat] mean and std.dev: (964.05, 1212.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9786)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 393, 596)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1340)
[M::mem_pestat] mean and std.dev: (322.58, 143.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1712)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 719046 sequences (100000155 bp) in 1.939 CPU sec, 1.970 real sec...
[M::mem_process_seqs] Processed 720158 reads in 225.406 CPU sec, 7.460 real sec
sorting block 42, #reads = 1093898 mem = 536877449 peak = 844378112
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 290162, 19, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (139, 342, 711)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1855)
[M::mem_pestat] mean and std.dev: (442.89, 398.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2427)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 199, 306)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 644)
[M::mem_pestat] mean and std.dev: (230.99, 123.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 813)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (83, 171, 853)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2393)
[M::mem_pestat] mean and std.dev: (390.28, 534.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3163)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 288, 461)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 999)
[M::mem_pestat] mean and std.dev: (279.64, 131.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1268)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 718444 sequences (100000070 bp) in 2.277 CPU sec, 2.365 real sec...
[M::mem_process_seqs] Processed 719150 reads in 126.698 CPU sec, 4.074 real sec
[M::mem_process_seqs] Processed 719482 reads in 326.657 CPU sec, 10.503 real sec
sorting block 43, #reads = 1092001 mem = 536878370 peak = 844378112
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 290215, 18, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 273, 1046)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2694)
[M::mem_pestat] mean and std.dev: (553.37, 572.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3518)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 199, 305)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 641)
[M::mem_pestat] mean and std.dev: (230.47, 122.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 809)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 279, 904)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2326)
[M::mem_pestat] mean and std.dev: (515.24, 562.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3037)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (232, 481, 1271)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3349)
[M::mem_pestat] mean and std.dev: (810.02, 748.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4388)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 718356 sequences (100000158 bp) in 3.131 CPU sec, 3.556 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 290346, 19, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 328, 991)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2679)
[M::mem_pestat] mean and std.dev: (564.17, 518.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3523)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 199, 307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 647)
[M::mem_pestat] mean and std.dev: (231.56, 123.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 817)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (238, 789, 2281)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6367)
[M::mem_pestat] mean and std.dev: (1276.22, 1377.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8410)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (263, 656, 674)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1496)
[M::mem_pestat] mean and std.dev: (468.32, 267.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1907)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 719046 reads in 243.652 CPU sec, 7.799 real sec
[M::process] read 718464 sequences (100000114 bp) in 2.256 CPU sec, 2.336 real sec...
[M::mem_process_seqs] Processed 718444 reads in 148.465 CPU sec, 4.797 real sec
sorting block 44, #reads = 1091104 mem = 536879782 peak = 844378112
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 290158, 28, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 466, 2232)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6338)
[M::mem_pestat] mean and std.dev: (1593.92, 2101.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10002)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 200, 306)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 644)
[M::mem_pestat] mean and std.dev: (231.37, 122.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 813)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 766, 1490)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4122)
[M::mem_pestat] mean and std.dev: (807.00, 706.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5438)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 357, 1032)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2662)
[M::mem_pestat] mean and std.dev: (559.41, 507.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3477)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 717066 sequences (100000025 bp) in 2.943 CPU sec, 3.245 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 289698, 11, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (369, 602, 1491)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3735)
[M::mem_pestat] mean and std.dev: (891.04, 1014.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4949)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 200, 306)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 644)
[M::mem_pestat] mean and std.dev: (231.12, 122.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 813)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (273, 538, 1489)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3921)
[M::mem_pestat] mean and std.dev: (824.64, 769.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5137)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 262, 412)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 838)
[M::mem_pestat] mean and std.dev: (278.26, 154.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1051)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 716998 sequences (100000214 bp) in 2.127 CPU sec, 2.138 real sec...
[M::mem_process_seqs] Processed 718356 reads in 226.832 CPU sec, 7.346 real sec
sorting block 45, #reads = 1092662 mem = 536882309 peak = 844378112
[M::mem_process_seqs] Processed 718464 reads in 147.463 CPU sec, 4.713 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 288951, 10, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 288, 811)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2109)
[M::mem_pestat] mean and std.dev: (440.67, 476.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2758)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 201, 306)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 642)
[M::mem_pestat] mean and std.dev: (231.70, 122.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 810)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (80, 490, 629)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1727)
[M::mem_pestat] mean and std.dev: (408.90, 389.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2276)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 375, 1331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3647)
[M::mem_pestat] mean and std.dev: (458.78, 445.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4805)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 46, #reads = 1091402 mem = 536886737 peak = 844378112
[M::process] read 718322 sequences (100000277 bp) in 3.140 CPU sec, 3.513 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (22, 288819, 17, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (141, 369, 394)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 900)
[M::mem_pestat] mean and std.dev: (240.35, 110.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1153)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (139, 201, 307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 643)
[M::mem_pestat] mean and std.dev: (232.40, 122.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 811)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (366, 1195, 5697)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 16359)
[M::mem_pestat] mean and std.dev: (2662.53, 2661.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 21690)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 288, 765)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1955)
[M::mem_pestat] mean and std.dev: (442.72, 366.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2550)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 717066 reads in 223.315 CPU sec, 7.174 real sec
[M::process] read 718064 sequences (100000048 bp) in 2.411 CPU sec, 2.438 real sec...
[M::mem_process_seqs] Processed 716998 reads in 152.982 CPU sec, 4.879 real sec
sorting block 47, #reads = 1089320 mem = 536881132 peak = 844378112
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 289742, 12, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 251, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 592)
[M::mem_pestat] mean and std.dev: (254.42, 86.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 724)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 197, 298)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 620)
[M::mem_pestat] mean and std.dev: (226.32, 117.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 781)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (414, 878, 1356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3240)
[M::mem_pestat] mean and std.dev: (679.64, 472.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4182)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 307, 390)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 788)
[M::mem_pestat] mean and std.dev: (273.96, 108.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 987)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 717862 sequences (100000085 bp) in 3.363 CPU sec, 3.721 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 289386, 12, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 223, 540)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1270)
[M::mem_pestat] mean and std.dev: (334.94, 281.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1635)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 198, 299)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 623)
[M::mem_pestat] mean and std.dev: (227.01, 117.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 785)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (248, 1142, 2161)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5987)
[M::mem_pestat] mean and std.dev: (1156.00, 1118.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7900)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 541, 752)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1822)
[M::mem_pestat] mean and std.dev: (479.81, 309.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2357)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 717808 sequences (100000158 bp) in 2.154 CPU sec, 2.159 real sec...
[M::mem_process_seqs] Processed 718322 reads in 225.008 CPU sec, 7.217 real sec
[M::mem_process_seqs] Processed 718064 reads in 147.001 CPU sec, 4.674 real sec
sorting block 48, #reads = 1089304 mem = 536876978 peak = 844378112
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 289899, 23, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 534, 825)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2131)
[M::mem_pestat] mean and std.dev: (453.90, 423.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2784)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 199, 300)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 624)
[M::mem_pestat] mean and std.dev: (227.79, 118.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 786)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (109, 375, 907)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2503)
[M::mem_pestat] mean and std.dev: (463.20, 581.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3301)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (245, 1215, 1519)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4067)
[M::mem_pestat] mean and std.dev: (891.32, 653.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5341)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 718016 sequences (100000121 bp) in 2.910 CPU sec, 3.421 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 289158, 25, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 319, 1407)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3895)
[M::mem_pestat] mean and std.dev: (631.38, 628.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5139)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 199, 300)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 624)
[M::mem_pestat] mean and std.dev: (227.85, 118.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 786)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (83, 621, 1244)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3566)
[M::mem_pestat] mean and std.dev: (730.56, 554.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4727)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 256, 951)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2537)
[M::mem_pestat] mean and std.dev: (405.65, 448.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3330)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 717702 sequences (100000264 bp) in 2.259 CPU sec, 2.291 real sec...
[M::mem_process_seqs] Processed 717862 reads in 227.778 CPU sec, 7.336 real sec
sorting block 49, #reads = 1089085 mem = 536879057 peak = 844378112
[M::mem_process_seqs] Processed 717808 reads in 142.902 CPU sec, 4.560 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 289208, 16, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 270, 453)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 959)
[M::mem_pestat] mean and std.dev: (310.65, 222.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1212)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 199, 301)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 627)
[M::mem_pestat] mean and std.dev: (228.19, 118.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 790)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (400, 523, 1343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3229)
[M::mem_pestat] mean and std.dev: (558.85, 402.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4172)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 301, 1122)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2960)
[M::mem_pestat] mean and std.dev: (556.63, 587.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3879)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 50, #reads = 1088765 mem = 536884040 peak = 844378112
[M::process] read 717654 sequences (100000269 bp) in 2.740 CPU sec, 3.082 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 289207, 20, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 262, 940)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2414)
[M::mem_pestat] mean and std.dev: (428.65, 351.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3151)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 199, 302)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 630)
[M::mem_pestat] mean and std.dev: (229.12, 119.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 794)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (252, 1115, 2135)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5901)
[M::mem_pestat] mean and std.dev: (1186.32, 1019.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7784)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 298, 541)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1253)
[M::mem_pestat] mean and std.dev: (330.16, 258.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1609)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 715920 sequences (100000059 bp) in 2.150 CPU sec, 2.240 real sec...
[M::mem_process_seqs] Processed 718016 reads in 227.517 CPU sec, 7.349 real sec
[M::mem_process_seqs] Processed 717702 reads in 144.471 CPU sec, 4.649 real sec
sorting block 51, #reads = 1088929 mem = 536878229 peak = 844378112
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 289365, 13, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (146, 453, 1367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3809)
[M::mem_pestat] mean and std.dev: (565.20, 758.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5030)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 200, 302)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 630)
[M::mem_pestat] mean and std.dev: (229.21, 119.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 794)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 595, 1167)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3069)
[M::mem_pestat] mean and std.dev: (602.23, 422.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4020)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 713, 4577)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13293)
[M::mem_pestat] mean and std.dev: (2283.76, 2990.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17651)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 717992 sequences (100000280 bp) in 3.406 CPU sec, 3.744 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 289178, 17, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 421, 972)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2558)
[M::mem_pestat] mean and std.dev: (629.00, 527.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3351)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (139, 203, 310)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 652)
[M::mem_pestat] mean and std.dev: (234.41, 124.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 823)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (756, 1165, 1287)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2349)
[M::mem_pestat] mean and std.dev: (1055.94, 432.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2880)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (236, 398, 638)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1442)
[M::mem_pestat] mean and std.dev: (420.80, 264.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1844)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 717654 reads in 224.261 CPU sec, 7.238 real sec
[M::process] read 728634 sequences (100000149 bp) in 2.519 CPU sec, 2.582 real sec...
[M::mem_process_seqs] Processed 715920 reads in 151.732 CPU sec, 4.849 real sec
sorting block 52, #reads = 1089276 mem = 536879074 peak = 844378112
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 290106, 19, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 386, 944)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2474)
[M::mem_pestat] mean and std.dev: (564.57, 590.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3239)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 199, 304)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 636)
[M::mem_pestat] mean and std.dev: (229.96, 121.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 802)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (286, 375, 628)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1312)
[M::mem_pestat] mean and std.dev: (419.53, 257.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1654)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (231, 398, 913)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2277)
[M::mem_pestat] mean and std.dev: (601.13, 612.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3050)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 727638 sequences (100000214 bp) in 3.723 CPU sec, 4.215 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23, 293157, 16, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (144, 236, 2164)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6204)
[M::mem_pestat] mean and std.dev: (1095.14, 1536.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8224)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 182, 271)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 555)
[M::mem_pestat] mean and std.dev: (207.53, 105.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 697)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (139, 1141, 1638)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4636)
[M::mem_pestat] mean and std.dev: (1083.67, 1055.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6135)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 299, 1044)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2722)
[M::mem_pestat] mean and std.dev: (585.44, 675.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3561)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 717992 reads in 234.694 CPU sec, 7.549 real sec
[M::mem_process_seqs] Processed 728634 reads in 159.728 CPU sec, 5.067 real sec
[M::process] read 726192 sequences (100000227 bp) in 2.724 CPU sec, 2.837 real sec...
sorting block 53, #reads = 1088082 mem = 536892912 peak = 844378112
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23, 293383, 15, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 556, 4359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12687)
[M::mem_pestat] mean and std.dev: (2000.74, 2717.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 16851)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 184, 276)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 568)
[M::mem_pestat] mean and std.dev: (210.81, 108.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 714)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (38, 77, 970)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2834)
[M::mem_pestat] mean and std.dev: (324.92, 526.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3766)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 470, 827)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2023)
[M::mem_pestat] mean and std.dev: (494.59, 345.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2621)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 54, #reads = 1091165 mem = 536892468 peak = 844378112
[M::process] read 724620 sequences (100000180 bp) in 3.168 CPU sec, 3.707 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 293473, 12, 23)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 262, 785)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2001)
[M::mem_pestat] mean and std.dev: (475.52, 477.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2609)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 186, 280)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 578)
[M::mem_pestat] mean and std.dev: (213.88, 111.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 727)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (86, 379, 2239)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6545)
[M::mem_pestat] mean and std.dev: (792.00, 948.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8698)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 243, 840)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2098)
[M::mem_pestat] mean and std.dev: (485.39, 433.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2727)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723036 sequences (100000257 bp) in 2.007 CPU sec, 2.054 real sec...
[M::mem_process_seqs] Processed 727638 reads in 237.435 CPU sec, 7.667 real sec
[M::mem_process_seqs] Processed 726192 reads in 153.322 CPU sec, 4.969 real sec
sorting block 55, #reads = 1093813 mem = 536891278 peak = 844378112
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 292703, 13, 21)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 286, 639)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1609)
[M::mem_pestat] mean and std.dev: (350.63, 363.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2094)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 188, 287)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 597)
[M::mem_pestat] mean and std.dev: (218.25, 114.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 752)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (379, 919, 2705)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7357)
[M::mem_pestat] mean and std.dev: (1408.15, 1365.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9683)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 259, 569)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1389)
[M::mem_pestat] mean and std.dev: (281.39, 189.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1799)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 721862 sequences (100000203 bp) in 3.041 CPU sec, 3.486 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 292015, 18, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (227, 323, 635)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1451)
[M::mem_pestat] mean and std.dev: (389.41, 287.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1859)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 191, 292)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 608)
[M::mem_pestat] mean and std.dev: (221.75, 117.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 766)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (38, 538, 574)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1646)
[M::mem_pestat] mean and std.dev: (404.82, 432.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2182)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 265, 532)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1210)
[M::mem_pestat] mean and std.dev: (235.90, 89.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1549)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 724620 reads in 232.497 CPU sec, 7.578 real sec
[M::process] read 721810 sequences (100000116 bp) in 2.388 CPU sec, 2.413 real sec...
[M::mem_process_seqs] Processed 723036 reads in 151.115 CPU sec, 4.853 real sec
sorting block 56, #reads = 1092965 mem = 536879255 peak = 844378112
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 291971, 6, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 365, 427)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 903)
[M::mem_pestat] mean and std.dev: (285.03, 135.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1141)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 193, 296)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 620)
[M::mem_pestat] mean and std.dev: (224.70, 119.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 782)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (246, 358, 954)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2370)
[M::mem_pestat] mean and std.dev: (532.04, 488.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3078)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 721876 sequences (100000050 bp) in 3.262 CPU sec, 3.710 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 291636, 11, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 239, 713)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1809)
[M::mem_pestat] mean and std.dev: (363.22, 326.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2357)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 193, 297)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 621)
[M::mem_pestat] mean and std.dev: (225.08, 120.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 783)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (404, 674, 2078)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5426)
[M::mem_pestat] mean and std.dev: (773.33, 723.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7100)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (260, 1116, 3517)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10031)
[M::mem_pestat] mean and std.dev: (2813.63, 3445.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 16596)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 721892 sequences (100000017 bp) in 2.110 CPU sec, 2.141 real sec...
[M::mem_process_seqs] Processed 721862 reads in 233.454 CPU sec, 7.526 real sec
[M::mem_process_seqs] Processed 721810 reads in 148.964 CPU sec, 4.836 real sec
sorting block 57, #reads = 1092672 mem = 536880593 peak = 844378112
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 291538, 24, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (248, 376, 1321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3467)
[M::mem_pestat] mean and std.dev: (523.11, 504.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4540)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 193, 297)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 623)
[M::mem_pestat] mean and std.dev: (225.28, 120.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 786)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (533, 906, 1257)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2705)
[M::mem_pestat] mean and std.dev: (774.48, 377.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3429)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 507, 1499)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4121)
[M::mem_pestat] mean and std.dev: (899.89, 884.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5432)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 721752 sequences (100000090 bp) in 2.896 CPU sec, 3.377 real sec...
sorting block 58, #reads = 1092387 mem = 536879622 peak = 844378112
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 291447, 18, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (142, 260, 497)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1207)
[M::mem_pestat] mean and std.dev: (289.44, 214.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1562)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 193, 297)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 623)
[M::mem_pestat] mean and std.dev: (225.33, 120.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 786)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (398, 421, 1022)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2270)
[M::mem_pestat] mean and std.dev: (591.76, 417.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2894)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 315, 481)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1005)
[M::mem_pestat] mean and std.dev: (330.90, 217.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1267)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722048 sequences (100000147 bp) in 2.472 CPU sec, 2.709 real sec...
[M::mem_process_seqs] Processed 721876 reads in 248.328 CPU sec, 8.104 real sec
[M::mem_process_seqs] Processed 721892 reads in 162.481 CPU sec, 5.246 real sec
sorting block 59, #reads = 1088487 mem = 536882455 peak = 844378112
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 291193, 20, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (254, 595, 2588)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7256)
[M::mem_pestat] mean and std.dev: (1186.19, 1147.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9590)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 193, 297)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 621)
[M::mem_pestat] mean and std.dev: (225.07, 119.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 783)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (314, 950, 2618)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7226)
[M::mem_pestat] mean and std.dev: (1202.50, 1083.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9530)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 313, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 617)
[M::mem_pestat] mean and std.dev: (254.03, 92.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 755)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720524 sequences (100000170 bp) in 3.113 CPU sec, 3.673 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 291724, 20, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 306, 487)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1095)
[M::mem_pestat] mean and std.dev: (321.34, 230.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1399)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 192, 295)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 617)
[M::mem_pestat] mean and std.dev: (223.69, 118.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 778)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (449, 1160, 1665)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4097)
[M::mem_pestat] mean and std.dev: (1088.68, 895.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5313)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (237, 356, 1193)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3105)
[M::mem_pestat] mean and std.dev: (587.60, 572.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4061)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720312 sequences (100000041 bp) in 2.091 CPU sec, 2.156 real sec...
[M::mem_process_seqs] Processed 721752 reads in 241.725 CPU sec, 7.821 real sec
[M::mem_process_seqs] Processed 722048 reads in 157.598 CPU sec, 5.117 real sec
sorting block 60, #reads = 1089538 mem = 536878431 peak = 844378112
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 291108, 15, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 223, 463)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1029)
[M::mem_pestat] mean and std.dev: (303.23, 180.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1312)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 195, 298)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 624)
[M::mem_pestat] mean and std.dev: (226.16, 119.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 787)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (58, 312, 1005)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2899)
[M::mem_pestat] mean and std.dev: (528.57, 625.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3846)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 360, 648)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1582)
[M::mem_pestat] mean and std.dev: (411.32, 290.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2049)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 719866 sequences (100000215 bp) in 2.810 CPU sec, 3.425 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 290784, 9, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 301, 1141)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2989)
[M::mem_pestat] mean and std.dev: (767.93, 909.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4406)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 195, 298)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 622)
[M::mem_pestat] mean and std.dev: (226.43, 120.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 784)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (301, 335, 695)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1483)
[M::mem_pestat] mean and std.dev: (388.58, 254.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1877)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 720290 sequences (100000183 bp) in 2.269 CPU sec, 2.274 real sec...
[M::mem_process_seqs] Processed 720524 reads in 241.906 CPU sec, 7.890 real sec
sorting block 61, #reads = 1089677 mem = 536880617 peak = 844378112
[M::mem_process_seqs] Processed 720312 reads in 157.049 CPU sec, 5.097 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 290404, 18, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 336, 507)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1105)
[M::mem_pestat] mean and std.dev: (351.52, 199.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1404)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 196, 299)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 625)
[M::mem_pestat] mean and std.dev: (227.26, 120.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 788)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 371, 662)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1572)
[M::mem_pestat] mean and std.dev: (402.31, 333.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2027)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (260, 369, 790)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1850)
[M::mem_pestat] mean and std.dev: (527.76, 479.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2446)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 718986 sequences (100000027 bp) in 3.233 CPU sec, 3.638 real sec...
sorting block 62, #reads = 1088974 mem = 536879885 peak = 844378112
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 290567, 14, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (235, 326, 571)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1243)
[M::mem_pestat] mean and std.dev: (352.34, 214.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1579)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 195, 297)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 619)
[M::mem_pestat] mean and std.dev: (225.63, 119.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 780)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 505, 939)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2519)
[M::mem_pestat] mean and std.dev: (674.14, 717.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3545)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 342, 615)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1449)
[M::mem_pestat] mean and std.dev: (379.46, 248.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1866)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 719362 sequences (100000204 bp) in 2.074 CPU sec, 2.106 real sec...
[M::mem_process_seqs] Processed 719866 reads in 245.405 CPU sec, 8.002 real sec
[M::mem_process_seqs] Processed 720290 reads in 157.110 CPU sec, 5.021 real sec
sorting block 63, #reads = 1087376 mem = 536879882 peak = 844378112
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 290221, 18, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 247, 645)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1535)
[M::mem_pestat] mean and std.dev: (336.66, 280.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1980)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 197, 301)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 629)
[M::mem_pestat] mean and std.dev: (228.62, 121.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 793)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (237, 422, 960)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2406)
[M::mem_pestat] mean and std.dev: (546.18, 386.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3129)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 288, 515)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1209)
[M::mem_pestat] mean and std.dev: (272.64, 194.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1556)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 718926 sequences (100000236 bp) in 3.040 CPU sec, 3.537 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 289904, 18, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (140, 322, 860)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2300)
[M::mem_pestat] mean and std.dev: (514.89, 510.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3020)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 197, 301)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 629)
[M::mem_pestat] mean and std.dev: (228.40, 121.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 793)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (377, 667, 770)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1556)
[M::mem_pestat] mean and std.dev: (657.12, 406.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2283)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (275, 332, 925)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2225)
[M::mem_pestat] mean and std.dev: (408.13, 287.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2875)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 718408 sequences (100000202 bp) in 2.099 CPU sec, 2.120 real sec...
[M::mem_process_seqs] Processed 718986 reads in 241.883 CPU sec, 7.857 real sec
[M::mem_process_seqs] Processed 719362 reads in 157.316 CPU sec, 5.059 real sec
sorting block 64, #reads = 1088526 mem = 536886116 peak = 844378112
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (17, 289539, 16, 24)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (237, 657, 3581)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10269)
[M::mem_pestat] mean and std.dev: (1535.00, 1498.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13613)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 197, 303)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 635)
[M::mem_pestat] mean and std.dev: (229.59, 122.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 801)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (279, 800, 1664)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4434)
[M::mem_pestat] mean and std.dev: (1069.19, 1012.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5819)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 247, 434)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 962)
[M::mem_pestat] mean and std.dev: (297.96, 210.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1226)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 732882 sequences (100000221 bp) in 3.230 CPU sec, 3.622 real sec...
[M::process] read 729648 sequences (100000052 bp) in 2.079 CPU sec, 2.204 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 289804, 20, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 926, 2102)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6002)
[M::mem_pestat] mean and std.dev: (1110.00, 1239.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7952)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 198, 305)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 641)
[M::mem_pestat] mean and std.dev: (230.79, 123.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 809)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 525, 1435)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3971)
[M::mem_pestat] mean and std.dev: (863.74, 1065.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5239)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 277, 452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 956)
[M::mem_pestat] mean and std.dev: (278.77, 166.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1208)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 718926 reads in 240.622 CPU sec, 7.747 real sec
sorting block 65, #reads = 1085632 mem = 536878301 peak = 844378112
[M::mem_process_seqs] Processed 718408 reads in 157.670 CPU sec, 5.070 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 295136, 18, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 244, 1227)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3359)
[M::mem_pestat] mean and std.dev: (653.16, 825.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4425)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (127, 177, 260)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 526)
[M::mem_pestat] mean and std.dev: (200.13, 98.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 659)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (369, 1089, 1442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3588)
[M::mem_pestat] mean and std.dev: (980.12, 741.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4661)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 286, 673)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1649)
[M::mem_pestat] mean and std.dev: (328.19, 232.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2137)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 728528 sequences (100000206 bp) in 3.094 CPU sec, 3.582 real sec...
sorting block 66, #reads = 1086376 mem = 536880124 peak = 844378112
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 294009, 22, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 277, 443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 991)
[M::mem_pestat] mean and std.dev: (354.42, 248.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1348)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 181, 271)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 555)
[M::mem_pestat] mean and std.dev: (207.68, 105.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 697)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 590, 1305)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3525)
[M::mem_pestat] mean and std.dev: (603.35, 499.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4635)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 302, 623)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1445)
[M::mem_pestat] mean and std.dev: (334.24, 224.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1856)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 727502 sequences (100000013 bp) in 2.309 CPU sec, 2.335 real sec...
[M::mem_process_seqs] Processed 732882 reads in 263.510 CPU sec, 8.521 real sec
[M::mem_process_seqs] Processed 729648 reads in 172.185 CPU sec, 5.550 real sec
sorting block 67, #reads = 1086879 mem = 536878039 peak = 844378112
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 293903, 24, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 232, 874)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2312)
[M::mem_pestat] mean and std.dev: (422.47, 390.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3031)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 183, 274)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 564)
[M::mem_pestat] mean and std.dev: (210.15, 107.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 709)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 334, 1344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3700)
[M::mem_pestat] mean and std.dev: (569.13, 593.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4878)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 319, 528)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1200)
[M::mem_pestat] mean and std.dev: (303.29, 199.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1536)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726990 sequences (100000172 bp) in 2.924 CPU sec, 3.665 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (19, 293147, 23, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (144, 278, 420)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 972)
[M::mem_pestat] mean and std.dev: (270.81, 167.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1248)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 185, 277)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 571)
[M::mem_pestat] mean and std.dev: (212.19, 108.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 718)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 554, 3093)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8893)
[M::mem_pestat] mean and std.dev: (1539.91, 1743.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11793)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 341, 2017)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5697)
[M::mem_pestat] mean and std.dev: (984.88, 1200.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7537)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725542 sequences (100000145 bp) in 2.126 CPU sec, 2.305 real sec...
[M::mem_process_seqs] Processed 728528 reads in 255.384 CPU sec, 8.644 real sec
[M::mem_process_seqs] Processed 727502 reads in 165.577 CPU sec, 5.515 real sec
sorting block 68, #reads = 1089522 mem = 536879193 peak = 844378112
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 293506, 18, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (229, 452, 924)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2314)
[M::mem_pestat] mean and std.dev: (610.33, 548.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3009)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 185, 280)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 578)
[M::mem_pestat] mean and std.dev: (213.70, 110.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 727)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (57, 269, 807)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2307)
[M::mem_pestat] mean and std.dev: (480.00, 603.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3057)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 385, 1821)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5039)
[M::mem_pestat] mean and std.dev: (752.90, 921.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6648)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723892 sequences (100000123 bp) in 3.077 CPU sec, 3.535 real sec...
[M::process] read 724276 sequences (100000022 bp) in 2.252 CPU sec, 2.274 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 292412, 14, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 260, 423)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 959)
[M::mem_pestat] mean and std.dev: (239.04, 133.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1227)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 187, 283)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 585)
[M::mem_pestat] mean and std.dev: (215.93, 112.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 736)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (237, 546, 1194)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3108)
[M::mem_pestat] mean and std.dev: (795.38, 799.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4065)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 495, 1611)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4433)
[M::mem_pestat] mean and std.dev: (979.60, 956.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5844)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 726990 reads in 251.753 CPU sec, 8.265 real sec
sorting block 69, #reads = 1086712 mem = 536879213 peak = 844378112
[M::mem_process_seqs] Processed 725542 reads in 160.281 CPU sec, 5.194 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 292148, 19, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 340, 408)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 818)
[M::mem_pestat] mean and std.dev: (285.47, 114.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1023)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 189, 289)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 601)
[M::mem_pestat] mean and std.dev: (219.47, 114.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 757)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (467, 983, 1705)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4181)
[M::mem_pestat] mean and std.dev: (968.33, 718.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5419)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 264, 1100)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2874)
[M::mem_pestat] mean and std.dev: (524.35, 630.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3761)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 70, #reads = 1087410 mem = 536877342 peak = 844378112
[M::process] read 722708 sequences (100000143 bp) in 3.329 CPU sec, 3.889 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 292476, 18, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (142, 331, 1287)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3577)
[M::mem_pestat] mean and std.dev: (667.88, 895.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4722)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 189, 287)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 595)
[M::mem_pestat] mean and std.dev: (218.93, 114.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 749)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (233, 904, 1591)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4307)
[M::mem_pestat] mean and std.dev: (672.07, 532.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5665)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 305, 795)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2007)
[M::mem_pestat] mean and std.dev: (335.71, 339.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2613)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724036 sequences (100000170 bp) in 2.049 CPU sec, 2.059 real sec...
[M::mem_process_seqs] Processed 723892 reads in 254.000 CPU sec, 8.289 real sec
[M::mem_process_seqs] Processed 724276 reads in 168.545 CPU sec, 5.451 real sec
sorting block 71, #reads = 1087761 mem = 536879434 peak = 844378112
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (22, 292114, 20, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 236, 660)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1668)
[M::mem_pestat] mean and std.dev: (341.55, 304.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2172)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 191, 291)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 605)
[M::mem_pestat] mean and std.dev: (221.66, 116.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 762)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (374, 478, 4701)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13355)
[M::mem_pestat] mean and std.dev: (2117.10, 2534.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17682)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 216, 652)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1638)
[M::mem_pestat] mean and std.dev: (318.63, 272.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2131)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722300 sequences (100000028 bp) in 2.980 CPU sec, 3.388 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 291842, 20, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 345, 588)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1382)
[M::mem_pestat] mean and std.dev: (320.61, 199.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1779)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 189, 287)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 595)
[M::mem_pestat] mean and std.dev: (218.72, 114.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 749)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 611, 1687)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4647)
[M::mem_pestat] mean and std.dev: (894.32, 921.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6127)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 327, 2548)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7280)
[M::mem_pestat] mean and std.dev: (1200.81, 1501.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9646)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 721838 sequences (100000282 bp) in 2.397 CPU sec, 2.452 real sec...
[M::mem_process_seqs] Processed 722708 reads in 251.015 CPU sec, 8.153 real sec
[M::mem_process_seqs] Processed 724036 reads in 165.002 CPU sec, 5.393 real sec
sorting block 72, #reads = 1088115 mem = 536882612 peak = 844378112
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 291061, 20, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (266, 349, 1499)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3965)
[M::mem_pestat] mean and std.dev: (721.42, 735.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5198)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 192, 292)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 608)
[M::mem_pestat] mean and std.dev: (222.17, 116.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 766)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (76, 270, 2082)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6094)
[M::mem_pestat] mean and std.dev: (898.40, 1076.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8100)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 615, 914)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2358)
[M::mem_pestat] mean and std.dev: (697.76, 612.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3146)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722358 sequences (100000124 bp) in 3.321 CPU sec, 3.948 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 291243, 13, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 277, 699)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1769)
[M::mem_pestat] mean and std.dev: (518.70, 558.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2754)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 192, 293)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 611)
[M::mem_pestat] mean and std.dev: (222.70, 117.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 770)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (36, 465, 2931)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8721)
[M::mem_pestat] mean and std.dev: (1518.00, 2022.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11616)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 437, 633)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1441)
[M::mem_pestat] mean and std.dev: (383.68, 206.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1845)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 722300 reads in 233.573 CPU sec, 7.625 real sec
[M::process] read 720998 sequences (100000196 bp) in 2.092 CPU sec, 2.107 real sec...
sorting block 73, #reads = 1087799 mem = 536878479 peak = 844378112
[M::mem_process_seqs] Processed 721838 reads in 153.337 CPU sec, 4.893 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 291572, 13, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 297, 958)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2528)
[M::mem_pestat] mean and std.dev: (364.94, 375.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3313)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 191, 290)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 602)
[M::mem_pestat] mean and std.dev: (221.05, 116.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 758)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (449, 895, 1381)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3245)
[M::mem_pestat] mean and std.dev: (994.17, 707.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4177)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 285, 650)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1614)
[M::mem_pestat] mean and std.dev: (364.06, 268.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2096)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 74, #reads = 1088695 mem = 536879925 peak = 844378112
[M::process] read 720594 sequences (100000115 bp) in 3.758 CPU sec, 4.037 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 291001, 19, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (135, 196, 856)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2298)
[M::mem_pestat] mean and std.dev: (327.97, 333.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3019)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 194, 298)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 624)
[M::mem_pestat] mean and std.dev: (225.79, 120.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 787)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (587, 831, 1474)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3248)
[M::mem_pestat] mean and std.dev: (812.94, 479.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4135)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 259, 649)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1603)
[M::mem_pestat] mean and std.dev: (371.95, 323.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2080)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 719924 sequences (100000136 bp) in 2.274 CPU sec, 2.277 real sec...
[M::mem_process_seqs] Processed 722358 reads in 237.685 CPU sec, 7.600 real sec
[M::mem_process_seqs] Processed 720998 reads in 158.114 CPU sec, 5.309 real sec
sorting block 75, #reads = 1089411 mem = 536880372 peak = 844378112
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 290434, 14, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 286, 814)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2124)
[M::mem_pestat] mean and std.dev: (430.66, 406.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2779)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 194, 299)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 627)
[M::mem_pestat] mean and std.dev: (226.38, 121.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 791)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (279, 1574, 1574)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4164)
[M::mem_pestat] mean and std.dev: (1197.21, 988.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5459)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (261, 438, 1119)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2835)
[M::mem_pestat] mean and std.dev: (630.56, 527.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3693)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 719728 sequences (100000012 bp) in 3.470 CPU sec, 3.651 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 290590, 20, 23)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 256, 1278)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3538)
[M::mem_pestat] mean and std.dev: (786.71, 960.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4668)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 196, 300)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 628)
[M::mem_pestat] mean and std.dev: (227.14, 121.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 792)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (608, 1388, 5424)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 15056)
[M::mem_pestat] mean and std.dev: (2729.00, 2650.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 19872)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 281, 409)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 819)
[M::mem_pestat] mean and std.dev: (255.16, 105.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1024)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 719922 sequences (100000174 bp) in 2.154 CPU sec, 2.154 real sec...
[M::mem_process_seqs] Processed 720594 reads in 246.168 CPU sec, 8.183 real sec
[M::mem_process_seqs] Processed 719924 reads in 158.361 CPU sec, 5.063 real sec
sorting block 76, #reads = 1087615 mem = 536883110 peak = 844378112
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 289754, 21, 17)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 268, 390)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 762)
[M::mem_pestat] mean and std.dev: (246.96, 98.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 948)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 196, 301)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 631)
[M::mem_pestat] mean and std.dev: (228.28, 122.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 796)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 819, 2787)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7975)
[M::mem_pestat] mean and std.dev: (1225.57, 1164.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10569)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 166, 277)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 511)
[M::mem_pestat] mean and std.dev: (188.47, 60.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 628)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 727224 sequences (100000274 bp) in 4.224 CPU sec, 4.516 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 289814, 21, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 299, 1735)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4781)
[M::mem_pestat] mean and std.dev: (743.04, 880.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6304)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 196, 301)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 631)
[M::mem_pestat] mean and std.dev: (227.74, 121.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 796)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (270, 943, 2078)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5694)
[M::mem_pestat] mean and std.dev: (1168.85, 1270.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7502)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 276, 465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1039)
[M::mem_pestat] mean and std.dev: (296.79, 167.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1326)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 719728 reads in 245.668 CPU sec, 7.888 real sec
sorting block 77, #reads = 1086565 mem = 536880563 peak = 844378112
[M::process] read 726298 sequences (100000126 bp) in 2.320 CPU sec, 2.392 real sec...
[M::mem_process_seqs] Processed 719922 reads in 169.106 CPU sec, 5.556 real sec
sorting block 78, #reads = 1082783 mem = 536877425 peak = 844378112
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 292718, 18, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 280, 958)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2494)
[M::mem_pestat] mean and std.dev: (417.67, 475.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3262)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 184, 277)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 571)
[M::mem_pestat] mean and std.dev: (211.68, 109.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 718)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (628, 1441, 1444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3076)
[M::mem_pestat] mean and std.dev: (1076.82, 663.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3892)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 252, 712)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1800)
[M::mem_pestat] mean and std.dev: (400.89, 397.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2344)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725190 sequences (100000258 bp) in 2.639 CPU sec, 2.845 real sec...
[M::process] read 723372 sequences (100000086 bp) in 2.051 CPU sec, 2.072 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 292194, 11, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 265, 758)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1908)
[M::mem_pestat] mean and std.dev: (364.90, 387.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2483)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 186, 280)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 578)
[M::mem_pestat] mean and std.dev: (213.49, 110.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 727)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 950, 1055)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2845)
[M::mem_pestat] mean and std.dev: (805.55, 674.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3740)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 326, 706)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1716)
[M::mem_pestat] mean and std.dev: (410.53, 304.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2221)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 727224 reads in 256.207 CPU sec, 8.428 real sec
[M::mem_process_seqs] Processed 726298 reads in 160.331 CPU sec, 5.221 real sec
sorting block 79, #reads = 1083165 mem = 536877155 peak = 844378112
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 292620, 8, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (141, 264, 389)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 885)
[M::mem_pestat] mean and std.dev: (234.91, 103.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1133)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 188, 285)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 591)
[M::mem_pestat] mean and std.dev: (217.09, 113.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 744)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 268, 439)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 977)
[M::mem_pestat] mean and std.dev: (282.88, 190.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1246)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 723220 sequences (100000091 bp) in 4.602 CPU sec, 4.917 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 292226, 15, 22)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 322, 800)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2052)
[M::mem_pestat] mean and std.dev: (408.88, 385.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2678)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 190, 289)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 601)
[M::mem_pestat] mean and std.dev: (219.84, 115.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 757)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (450, 1493, 2623)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6969)
[M::mem_pestat] mean and std.dev: (1089.67, 852.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9142)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 278, 459)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1117)
[M::mem_pestat] mean and std.dev: (306.76, 198.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1446)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 725190 reads in 229.253 CPU sec, 7.450 real sec
[M::mem_process_seqs] Processed 723372 reads in 148.828 CPU sec, 4.745 real sec
sorting block 80, #reads = 1090616 mem = 536877094 peak = 844378112
[M::process] read 723248 sequences (100000241 bp) in 2.691 CPU sec, 2.859 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 292308, 30, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 295, 1179)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3221)
[M::mem_pestat] mean and std.dev: (515.67, 466.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4242)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 190, 291)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 607)
[M::mem_pestat] mean and std.dev: (220.85, 116.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 765)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 352, 644)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1558)
[M::mem_pestat] mean and std.dev: (353.12, 263.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2015)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 762, 2394)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6784)
[M::mem_pestat] mean and std.dev: (1374.24, 1259.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8979)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722256 sequences (100000297 bp) in 3.000 CPU sec, 3.160 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 291681, 18, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 302, 432)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 914)
[M::mem_pestat] mean and std.dev: (287.76, 162.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1155)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 191, 292)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 610)
[M::mem_pestat] mean and std.dev: (221.56, 117.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 769)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (46, 526, 666)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1906)
[M::mem_pestat] mean and std.dev: (480.00, 392.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2526)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (250, 601, 893)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2179)
[M::mem_pestat] mean and std.dev: (594.50, 425.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2822)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722082 sequences (100000268 bp) in 2.007 CPU sec, 2.014 real sec...
[M::mem_process_seqs] Processed 723220 reads in 217.628 CPU sec, 6.939 real sec
sorting block 81, #reads = 1091356 mem = 536881547 peak = 844378112
[M::mem_process_seqs] Processed 723248 reads in 140.933 CPU sec, 4.467 real sec
sorting block 82, #reads = 1092477 mem = 536878349 peak = 844378112
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 291538, 22, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (252, 360, 795)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1881)
[M::mem_pestat] mean and std.dev: (397.12, 278.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2424)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 193, 295)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 617)
[M::mem_pestat] mean and std.dev: (223.41, 118.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 778)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 1115, 1343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3587)
[M::mem_pestat] mean and std.dev: (972.19, 774.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4709)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 529, 969)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2575)
[M::mem_pestat] mean and std.dev: (529.73, 360.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3378)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722232 sequences (100000238 bp) in 3.260 CPU sec, 3.416 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 292171, 23, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 263, 916)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2404)
[M::mem_pestat] mean and std.dev: (499.46, 508.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3148)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 193, 295)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 617)
[M::mem_pestat] mean and std.dev: (223.52, 118.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 778)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (130, 578, 2665)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7735)
[M::mem_pestat] mean and std.dev: (1079.45, 1224.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10270)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (312, 576, 3512)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9912)
[M::mem_pestat] mean and std.dev: (2122.45, 2501.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13112)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720414 sequences (100000194 bp) in 2.140 CPU sec, 2.136 real sec...
[M::mem_process_seqs] Processed 722256 reads in 209.196 CPU sec, 6.662 real sec
[M::mem_process_seqs] Processed 722082 reads in 134.892 CPU sec, 4.284 real sec
sorting block 83, #reads = 1092098 mem = 536879853 peak = 844378112
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 291638, 21, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (234, 608, 691)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1605)
[M::mem_pestat] mean and std.dev: (548.92, 348.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2062)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 193, 294)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 614)
[M::mem_pestat] mean and std.dev: (223.22, 117.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 774)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (107, 257, 713)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1925)
[M::mem_pestat] mean and std.dev: (403.67, 354.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2531)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 351, 1249)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3371)
[M::mem_pestat] mean and std.dev: (527.07, 631.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4432)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720516 sequences (100000012 bp) in 3.089 CPU sec, 3.266 real sec...
[M::process] read 720864 sequences (100000105 bp) in 2.180 CPU sec, 2.172 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 291275, 15, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 316, 643)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1493)
[M::mem_pestat] mean and std.dev: (367.47, 263.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1918)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 195, 299)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 627)
[M::mem_pestat] mean and std.dev: (226.15, 119.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 791)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (448, 970, 1829)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4591)
[M::mem_pestat] mean and std.dev: (1269.14, 1097.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5972)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 256, 533)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1267)
[M::mem_pestat] mean and std.dev: (340.21, 242.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1634)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 722232 reads in 220.209 CPU sec, 7.060 real sec
[M::mem_process_seqs] Processed 720414 reads in 140.632 CPU sec, 4.478 real sec
sorting block 84, #reads = 1090347 mem = 536883047 peak = 844378112
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 291318, 20, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 308, 644)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1540)
[M::mem_pestat] mean and std.dev: (367.91, 249.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1988)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 195, 300)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 630)
[M::mem_pestat] mean and std.dev: (227.03, 120.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 795)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (293, 1904, 2755)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7679)
[M::mem_pestat] mean and std.dev: (1819.65, 1574.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10141)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 335, 4279)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12409)
[M::mem_pestat] mean and std.dev: (2314.93, 3478.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 16474)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 719982 sequences (100000177 bp) in 3.091 CPU sec, 3.260 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 291238, 19, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 264, 1461)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4007)
[M::mem_pestat] mean and std.dev: (712.17, 659.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5280)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 195, 299)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 627)
[M::mem_pestat] mean and std.dev: (226.25, 120.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 791)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (61, 982, 1348)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3922)
[M::mem_pestat] mean and std.dev: (883.11, 755.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5209)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 230, 304)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 590)
[M::mem_pestat] mean and std.dev: (211.19, 76.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 733)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720210 sequences (100000281 bp) in 2.139 CPU sec, 2.149 real sec...
[M::mem_process_seqs] Processed 720516 reads in 219.907 CPU sec, 7.041 real sec
sorting block 85, #reads = 1089440 mem = 536880032 peak = 844378112
[M::mem_process_seqs] Processed 720864 reads in 140.897 CPU sec, 4.587 real sec
sorting block 86, #reads = 1090913 mem = 536880470 peak = 844378112
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 290278, 12, 23)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (259, 357, 1103)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2791)
[M::mem_pestat] mean and std.dev: (606.06, 596.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3635)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 196, 300)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 628)
[M::mem_pestat] mean and std.dev: (227.33, 121.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 792)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 627, 1220)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3262)
[M::mem_pestat] mean and std.dev: (695.45, 709.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4283)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 303, 839)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2087)
[M::mem_pestat] mean and std.dev: (480.30, 333.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2711)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 719798 sequences (100000130 bp) in 3.056 CPU sec, 3.223 real sec...
[M::process] read 719952 sequences (100000222 bp) in 2.184 CPU sec, 2.185 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 290065, 15, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 262, 630)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1528)
[M::mem_pestat] mean and std.dev: (414.09, 371.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1977)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 196, 299)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 625)
[M::mem_pestat] mean and std.dev: (226.72, 120.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 788)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (95, 359, 660)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1790)
[M::mem_pestat] mean and std.dev: (463.07, 515.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2527)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 375, 662)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1528)
[M::mem_pestat] mean and std.dev: (419.52, 238.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1961)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 719982 reads in 228.280 CPU sec, 7.367 real sec
[M::mem_process_seqs] Processed 720210 reads in 146.818 CPU sec, 4.660 real sec
sorting block 87, #reads = 1088289 mem = 536882926 peak = 844378112
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 289844, 10, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 305, 791)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2011)
[M::mem_pestat] mean and std.dev: (405.34, 337.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2621)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 196, 299)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 625)
[M::mem_pestat] mean and std.dev: (227.00, 120.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 788)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (486, 689, 956)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1896)
[M::mem_pestat] mean and std.dev: (576.38, 176.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2366)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 326, 1059)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2783)
[M::mem_pestat] mean and std.dev: (590.83, 653.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3645)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720144 sequences (100000121 bp) in 3.058 CPU sec, 3.250 real sec...
[M::process] read 720530 sequences (100000157 bp) in 2.187 CPU sec, 2.190 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (17, 290357, 21, 21)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 241, 963)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2515)
[M::mem_pestat] mean and std.dev: (466.00, 595.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3291)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 195, 298)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 622)
[M::mem_pestat] mean and std.dev: (226.22, 119.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 784)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (378, 643, 1459)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3621)
[M::mem_pestat] mean and std.dev: (838.70, 632.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4702)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 199, 310)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 600)
[M::mem_pestat] mean and std.dev: (198.71, 64.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 745)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 719798 reads in 232.519 CPU sec, 7.519 real sec
[M::mem_process_seqs] Processed 719952 reads in 149.538 CPU sec, 4.774 real sec
sorting block 88, #reads = 1088420 mem = 536878471 peak = 844378112
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 290025, 14, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 288, 430)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 902)
[M::mem_pestat] mean and std.dev: (264.11, 106.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1138)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 195, 297)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 619)
[M::mem_pestat] mean and std.dev: (225.54, 119.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 780)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (239, 397, 426)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 800)
[M::mem_pestat] mean and std.dev: (282.09, 121.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 987)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 322, 1420)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3850)
[M::mem_pestat] mean and std.dev: (678.36, 565.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5065)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 719326 sequences (100000221 bp) in 3.433 CPU sec, 3.677 real sec...
[M::process] read 724918 sequences (100000009 bp) in 2.056 CPU sec, 2.066 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 290455, 19, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 348, 880)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2248)
[M::mem_pestat] mean and std.dev: (461.83, 447.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2932)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 195, 297)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 619)
[M::mem_pestat] mean and std.dev: (225.20, 119.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 780)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (130, 585, 1108)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3064)
[M::mem_pestat] mean and std.dev: (745.74, 751.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4042)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 408, 1148)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3048)
[M::mem_pestat] mean and std.dev: (607.08, 541.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3998)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 720144 reads in 239.529 CPU sec, 7.752 real sec
sorting block 89, #reads = 1086791 mem = 536878552 peak = 844378112
[M::mem_process_seqs] Processed 720530 reads in 152.983 CPU sec, 4.928 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 289380, 21, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 236, 689)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1711)
[M::mem_pestat] mean and std.dev: (333.65, 279.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2222)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 197, 301)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 631)
[M::mem_pestat] mean and std.dev: (227.84, 120.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 796)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (276, 512, 1454)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3810)
[M::mem_pestat] mean and std.dev: (689.47, 662.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4988)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 351, 573)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1313)
[M::mem_pestat] mean and std.dev: (367.97, 206.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1683)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 90, #reads = 1086789 mem = 536888817 peak = 844378112
[M::process] read 732696 sequences (100000071 bp) in 3.349 CPU sec, 3.517 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 291370, 19, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (223, 337, 924)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2326)
[M::mem_pestat] mean and std.dev: (497.88, 489.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3027)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 187, 283)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 585)
[M::mem_pestat] mean and std.dev: (215.65, 112.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 736)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (570, 1127, 2442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6186)
[M::mem_pestat] mean and std.dev: (1428.39, 1269.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8058)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 252, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 763)
[M::mem_pestat] mean and std.dev: (247.26, 133.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 961)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 729592 sequences (100000065 bp) in 2.237 CPU sec, 2.234 real sec...
[M::mem_process_seqs] Processed 719326 reads in 250.510 CPU sec, 8.071 real sec
[M::mem_process_seqs] Processed 724918 reads in 176.158 CPU sec, 5.610 real sec
sorting block 91, #reads = 1083962 mem = 536883493 peak = 844378112
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (22, 294607, 17, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (143, 229, 663)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1703)
[M::mem_pestat] mean and std.dev: (324.60, 261.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2223)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (127, 177, 261)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 529)
[M::mem_pestat] mean and std.dev: (200.82, 99.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 663)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (128, 526, 1065)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2939)
[M::mem_pestat] mean and std.dev: (494.00, 363.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3876)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (242, 373, 601)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1319)
[M::mem_pestat] mean and std.dev: (401.68, 260.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1678)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 727260 sequences (100000124 bp) in 3.855 CPU sec, 4.166 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 293519, 11, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 184, 802)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2110)
[M::mem_pestat] mean and std.dev: (354.36, 397.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2764)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 181, 270)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 552)
[M::mem_pestat] mean and std.dev: (206.99, 104.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 693)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (963, 1442, 1957)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3945)
[M::mem_pestat] mean and std.dev: (1038.89, 714.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4939)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (242, 414, 1211)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3149)
[M::mem_pestat] mean and std.dev: (526.31, 483.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4118)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726394 sequences (100000206 bp) in 2.350 CPU sec, 2.366 real sec...
[M::mem_process_seqs] Processed 732696 reads in 245.806 CPU sec, 7.836 real sec
[M::mem_process_seqs] Processed 729592 reads in 157.893 CPU sec, 5.045 real sec
sorting block 92, #reads = 1079859 mem = 536880675 peak = 844378112
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 293246, 15, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 277, 426)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 892)
[M::mem_pestat] mean and std.dev: (300.89, 199.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1125)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 185, 277)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 569)
[M::mem_pestat] mean and std.dev: (212.01, 108.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 715)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (555, 887, 2976)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7818)
[M::mem_pestat] mean and std.dev: (1782.27, 1957.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10239)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 280, 639)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1609)
[M::mem_pestat] mean and std.dev: (345.44, 269.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2094)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726010 sequences (100000062 bp) in 4.370 CPU sec, 4.685 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 293089, 6, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 266, 517)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1249)
[M::mem_pestat] mean and std.dev: (269.26, 184.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1615)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 186, 280)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 578)
[M::mem_pestat] mean and std.dev: (213.92, 110.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 727)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 382, 990)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2582)
[M::mem_pestat] mean and std.dev: (524.03, 398.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3378)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 727260 reads in 234.242 CPU sec, 7.499 real sec
sorting block 93, #reads = 1088046 mem = 536883994 peak = 844378112
[M::mem_process_seqs] Processed 726394 reads in 158.240 CPU sec, 5.018 real sec
[M::process] read 724154 sequences (100000254 bp) in 3.509 CPU sec, 3.743 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 292174, 15, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 245, 745)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1861)
[M::mem_pestat] mean and std.dev: (395.48, 367.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2419)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 186, 281)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 581)
[M::mem_pestat] mean and std.dev: (214.58, 111.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 731)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (577, 1010, 1601)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3649)
[M::mem_pestat] mean and std.dev: (772.75, 528.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4673)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 343, 1123)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3003)
[M::mem_pestat] mean and std.dev: (537.20, 457.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3943)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 94, #reads = 1088727 mem = 536880008 peak = 844378112
[M::process] read 723608 sequences (100000282 bp) in 4.130 CPU sec, 4.417 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 291891, 13, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 252, 1279)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3443)
[M::mem_pestat] mean and std.dev: (613.42, 699.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4525)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 188, 285)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 591)
[M::mem_pestat] mean and std.dev: (217.50, 113.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 744)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (45, 466, 1796)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5298)
[M::mem_pestat] mean and std.dev: (661.42, 854.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7049)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (233, 314, 1401)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3737)
[M::mem_pestat] mean and std.dev: (870.70, 937.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4905)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 726010 reads in 238.838 CPU sec, 7.647 real sec
[M::mem_process_seqs] Processed 724154 reads in 154.691 CPU sec, 4.895 real sec
[M::process] read 723784 sequences (100000188 bp) in 3.057 CPU sec, 3.200 real sec...
sorting block 95, #reads = 1086426 mem = 536882578 peak = 844378112
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 291714, 21, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 268, 1277)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3525)
[M::mem_pestat] mean and std.dev: (715.69, 856.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4649)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 189, 288)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 598)
[M::mem_pestat] mean and std.dev: (219.38, 114.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 753)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (463, 853, 6153)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 17533)
[M::mem_pestat] mean and std.dev: (2509.62, 3398.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 23223)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 347, 515)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1135)
[M::mem_pestat] mean and std.dev: (291.20, 130.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1445)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720840 sequences (100000142 bp) in 3.993 CPU sec, 4.340 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 291405, 16, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 265, 439)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 959)
[M::mem_pestat] mean and std.dev: (287.64, 173.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1219)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 189, 285)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 589)
[M::mem_pestat] mean and std.dev: (217.94, 112.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 741)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 1356, 2684)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7694)
[M::mem_pestat] mean and std.dev: (1773.19, 1931.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10199)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 277, 947)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2485)
[M::mem_pestat] mean and std.dev: (448.61, 429.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3254)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 723608 reads in 239.093 CPU sec, 7.652 real sec
[M::mem_process_seqs] Processed 723784 reads in 161.080 CPU sec, 5.110 real sec
sorting block 96, #reads = 1088441 mem = 536882062 peak = 844378112
[M::process] read 720990 sequences (100000191 bp) in 3.503 CPU sec, 3.691 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 290621, 25, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 274, 778)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1942)
[M::mem_pestat] mean and std.dev: (304.12, 212.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2524)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 194, 296)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 618)
[M::mem_pestat] mean and std.dev: (225.15, 118.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 779)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 668, 1852)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5224)
[M::mem_pestat] mean and std.dev: (950.08, 1163.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6910)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 468, 1590)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4418)
[M::mem_pestat] mean and std.dev: (1094.87, 1335.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6438)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 721270 sequences (100000119 bp) in 3.597 CPU sec, 3.827 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 290807, 17, 24)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (267, 383, 450)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 816)
[M::mem_pestat] mean and std.dev: (344.61, 151.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 999)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 194, 295)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 615)
[M::mem_pestat] mean and std.dev: (224.04, 117.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 775)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (601, 1099, 4103)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 11107)
[M::mem_pestat] mean and std.dev: (2304.00, 2997.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14609)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 404, 595)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1509)
[M::mem_pestat] mean and std.dev: (316.95, 190.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1966)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720710 sequences (100000029 bp) in 2.032 CPU sec, 2.036 real sec...
[M::mem_process_seqs] Processed 720840 reads in 240.005 CPU sec, 7.687 real sec
sorting block 97, #reads = 1086786 mem = 536880881 peak = 844378112
[M::mem_process_seqs] Processed 720990 reads in 157.552 CPU sec, 5.017 real sec
sorting block 98, #reads = 1085923 mem = 536879236 peak = 844378112
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 290677, 17, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (234, 294, 390)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 702)
[M::mem_pestat] mean and std.dev: (254.23, 99.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 858)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 192, 291)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 603)
[M::mem_pestat] mean and std.dev: (221.92, 115.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 759)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (138, 681, 3090)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8994)
[M::mem_pestat] mean and std.dev: (1584.00, 1842.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11946)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 332, 577)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1367)
[M::mem_pestat] mean and std.dev: (343.62, 197.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1762)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720646 sequences (100000202 bp) in 3.354 CPU sec, 3.634 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 290822, 15, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 439, 1204)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3290)
[M::mem_pestat] mean and std.dev: (681.03, 701.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4333)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 194, 294)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 612)
[M::mem_pestat] mean and std.dev: (223.64, 116.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 771)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (467, 864, 1570)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3776)
[M::mem_pestat] mean and std.dev: (616.75, 425.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4879)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 273, 432)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 952)
[M::mem_pestat] mean and std.dev: (278.52, 149.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1212)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720606 sequences (100000106 bp) in 2.662 CPU sec, 2.682 real sec...
[M::mem_process_seqs] Processed 721270 reads in 237.876 CPU sec, 7.689 real sec
[M::mem_process_seqs] Processed 720710 reads in 154.934 CPU sec, 5.001 real sec
sorting block 99, #reads = 1086274 mem = 536881344 peak = 844378112
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 290267, 27, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 517, 1289)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3461)
[M::mem_pestat] mean and std.dev: (569.91, 471.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4547)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 194, 295)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 615)
[M::mem_pestat] mean and std.dev: (224.16, 117.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 775)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 663, 2863)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8289)
[M::mem_pestat] mean and std.dev: (1647.41, 2186.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11002)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 305, 376)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 750)
[M::mem_pestat] mean and std.dev: (264.08, 122.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 937)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720620 sequences (100000032 bp) in 2.862 CPU sec, 3.056 real sec...
[M::process] read 720544 sequences (100000150 bp) in 2.105 CPU sec, 2.107 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 290925, 12, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 211, 636)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1548)
[M::mem_pestat] mean and std.dev: (368.04, 315.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2004)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 194, 295)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 613)
[M::mem_pestat] mean and std.dev: (224.44, 117.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 772)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (131, 358, 3849)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 11285)
[M::mem_pestat] mean and std.dev: (1399.17, 1647.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 15003)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 465, 752)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1922)
[M::mem_pestat] mean and std.dev: (443.39, 355.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2507)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 720646 reads in 232.531 CPU sec, 7.527 real sec
[M::mem_process_seqs] Processed 720606 reads in 150.298 CPU sec, 4.800 real sec
sorting block 100, #reads = 1086892 mem = 536878578 peak = 844378112
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 290646, 20, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 363, 1133)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2951)
[M::mem_pestat] mean and std.dev: (415.71, 329.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3860)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 194, 296)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 618)
[M::mem_pestat] mean and std.dev: (224.85, 119.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 779)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (322, 886, 1152)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2812)
[M::mem_pestat] mean and std.dev: (751.25, 434.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3642)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 288, 682)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1694)
[M::mem_pestat] mean and std.dev: (446.69, 381.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2200)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 718876 sequences (100000100 bp) in 3.291 CPU sec, 3.492 real sec...
[M::process] read 719304 sequences (100000294 bp) in 1.920 CPU sec, 1.925 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 290487, 15, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 302, 550)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1352)
[M::mem_pestat] mean and std.dev: (340.11, 291.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1753)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 194, 296)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 618)
[M::mem_pestat] mean and std.dev: (225.18, 119.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 779)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (227, 415, 984)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2498)
[M::mem_pestat] mean and std.dev: (617.80, 594.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3255)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 342, 1007)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2575)
[M::mem_pestat] mean and std.dev: (451.72, 409.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3359)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 720620 reads in 225.987 CPU sec, 7.225 real sec
sorting block 101, #reads = 1088061 mem = 536880935 peak = 844378112
[M::process] read 122408 sequences (16976242 bp) in 0.528 CPU sec, 0.536 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 290314, 12, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (138, 258, 703)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1833)
[M::mem_pestat] mean and std.dev: (439.09, 410.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2398)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 198, 305)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 641)
[M::mem_pestat] mean and std.dev: (230.27, 123.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 809)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (566, 976, 3621)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9731)
[M::mem_pestat] mean and std.dev: (1642.25, 1609.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12786)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 402, 1684)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4742)
[M::mem_pestat] mean and std.dev: (870.21, 878.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6271)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 718876 reads in 119.478 CPU sec, 3.910 real sec
sorting block 102, #reads = 1089279 mem = 536879080 peak = 844378112
[M::mem_process_seqs] Processed 720544 reads in 317.906 CPU sec, 10.255 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 290146, 15, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (267, 327, 601)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1269)
[M::mem_pestat] mean and std.dev: (395.54, 210.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1603)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 197, 300)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 628)
[M::mem_pestat] mean and std.dev: (227.54, 120.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 792)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (271, 508, 1464)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3850)
[M::mem_pestat] mean and std.dev: (892.21, 988.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5043)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 310, 634)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1414)
[M::mem_pestat] mean and std.dev: (337.62, 204.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1804)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (6, 49398, 8, 8)
[M::mem_pestat] skip orientation FF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 194, 296)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 618)
[M::mem_pestat] mean and std.dev: (224.81, 118.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 779)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] skip orientation RR as there are not enough pairs
[M::mem_process_seqs] Processed 719304 reads in 156.334 CPU sec, 5.094 real sec
sorting block 103, #reads = 1087012 mem = 536878090 peak = 844378112
[M::mem_process_seqs] Processed 122408 reads in 41.398 CPU sec, 1.339 real sec
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000a06d1
  features: 1f8bfbff fffab20b
  extended: f1bf27eb 1b407f7e
  amd bits: 2c100800 00000121
     brand: Intel(R) Xeon(R) 6975P-C
threads: 31
algo: bwa-mem
license: sentieon:klib=31
reads: 113285084
overall: 69796884480 mem 21980.909 user 807.683 sys 772.461 real
[main] Version: 0.7.17-r1188
[main] CMD: /opt/conda/share/sentieon-202308.03-3/libexec/bwa mem -K 100000000 -Y -R @RG\tID:A23MHWWLT4.1136_8DV-T1-TDNA-1_A23MHWWLT4_1.L007\tPU:L007\tSM:1136_8DV-T1-TDNA-1_A23MHWWLT4_1\tLB:1136_8DV-T1-TDNA-1_A23MHWWLT4_1\tDS:s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta\tPL:ILLUMINA -t 31 ./BWAIndex/Homo_sapiens_assembly38.fasta.64 1136_8DV-T1-TDNA-1_A23MHWWLT4_1_R1.fastq.gz 1136_8DV-T1-TDNA-1_A23MHWWLT4_1_R2.fastq.gz
[main] Real time: 772.496 sec; CPU: 22788.596 sec
sorting block 104, #reads = 836969 mem = 413974971 peak = 844378112
uniq header count 1
merging 105 blocks
sw version: sentieon-genomics-202308.03
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000a06d1
  features: 1f8bfbff fffab20b
  extended: f1bf27eb 1b407f7e
  amd bits: 2c100800 00000121
     brand: Intel(R) Xeon(R) 6975P-C
threads: 31 max 384
algo: util-sort
license: sentieon:util=1
output file size: 6302001014
output reads: 114120150
bam_mem_sort: 105 calls 85.561 user 1.523 sys 88.481 real
bam_write: 105 calls 64.628 user 6.148 sys 113.021 real
execute: 1 calls 42.809 user 2.177 sys 820.667 real
merge_files: 1 calls 42.773 user 2.159 sys 47.536 real
parse_chunk: 1677 calls 79.724 user 22.734 sys 119.327 real
read_chunk: 4545 calls 58.727 user 27.140 sys 666.665 real
sort_block: 1 calls 45.146 user 26.448 sys 646.345 real
write_chunk: 2866 calls 42.289 user 1.737 sys 46.378 real
overall: 3034587136 mem 1712.781 user 86.585 sys 820.685 real
ls: cannot access '*.cram': No such file or directory