Downloading: s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/ff/f45da014b5017879254dfb38b7af54/.command.sh
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/a5/120adef0223f5dc34b2c3c4aff82ee/659_dm4-T1-TDNA-1_A23MHWWLT4_1/659_dm4-T1-TDNA-1_A23MHWWLT4_1_R1.fastq.gz
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/a5/120adef0223f5dc34b2c3c4aff82ee/659_dm4-T1-TDNA-1_A23MHWWLT4_1/659_dm4-T1-TDNA-1_A23MHWWLT4_1_R2.fastq.gz
Downloading: s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta.fai
Downloading: s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/BWAIndex
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/ff/f45da014b5017879254dfb38b7af54/.command.run
==> STAGING COMPLETE (7 inputs)
cmdline: /opt/conda/share/sentieon-202308.03-3/libexec/util sort -r Homo_sapiens_assembly38.fasta -t 31 -o 659_dm4-T1-TDNA-1_A23MHWWLT4_1.bam --sam2bam -
This software is licensed to bgold@natera.com by Sentieon Inc.
This software is licensed to bgold@natera.com by Sentieon Inc.
version: sentieon-genomics-202308.03
[M::bwa_idx_load_from_disk] read 3171 ALT contigs
[M::main_mem] bwa index loaded in 2574.807 CPU sec, 89.726 real sec
[M::process] read 757748 sequences (100000067 bp) in 1.001 CPU sec, 1.004 real sec...
[M::process] read 756418 sequences (100000190 bp) in 1.711 CPU sec, 1.806 real sec...
[M::process] read 756404 sequences (100000133 bp) in 1.853 CPU sec, 1.911 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 304415, 27, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (146, 260, 1231)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3401)
[M::mem_pestat] mean and std.dev: (580.50, 700.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4486)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (114, 155, 210)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 402)
[M::mem_pestat] mean and std.dev: (167.27, 69.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 498)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (87, 526, 764)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2118)
[M::mem_pestat] mean and std.dev: (441.58, 429.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2795)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 314, 840)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2228)
[M::mem_pestat] mean and std.dev: (398.61, 345.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2922)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 755686 sequences (100000018 bp) in 1.673 CPU sec, 1.689 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 303667, 24, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 529, 1447)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3949)
[M::mem_pestat] mean and std.dev: (657.21, 709.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5200)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (115, 155, 211)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 403)
[M::mem_pestat] mean and std.dev: (168.11, 70.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 499)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (259, 478, 691)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1555)
[M::mem_pestat] mean and std.dev: (419.64, 261.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1987)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 451, 731)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1849)
[M::mem_pestat] mean and std.dev: (530.21, 508.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2562)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 303952, 22, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (129, 615, 1477)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4173)
[M::mem_pestat] mean and std.dev: (830.04, 910.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5521)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (115, 155, 212)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 406)
[M::mem_pestat] mean and std.dev: (168.17, 70.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 503)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 360, 719)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1853)
[M::mem_pestat] mean and std.dev: (371.75, 281.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2420)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 347, 1076)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2868)
[M::mem_pestat] mean and std.dev: (558.59, 491.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3764)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 757748 reads in 317.493 CPU sec, 10.208 real sec
[M::mem_process_seqs] Processed 756404 reads in 207.674 CPU sec, 6.683 real sec
[M::mem_process_seqs] Processed 756418 reads in 229.281 CPU sec, 7.390 real sec
sorting block 0, #reads = 1119384 mem = 536880509 peak = 590426112
[M::process] read 754102 sequences (100000115 bp) in 2.302 CPU sec, 2.413 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 304319, 10, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 291, 1112)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3018)
[M::mem_pestat] mean and std.dev: (679.11, 673.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3971)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (115, 156, 212)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 406)
[M::mem_pestat] mean and std.dev: (168.54, 70.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 503)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (459, 3433, 5863)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 16671)
[M::mem_pestat] mean and std.dev: (3314.00, 3008.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 22075)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (143, 244, 387)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 875)
[M::mem_pestat] mean and std.dev: (295.89, 212.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1148)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 1, #reads = 1119006 mem = 536882890 peak = 857812992
[M::process] read 753192 sequences (100000116 bp) in 2.130 CPU sec, 2.177 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 303351, 18, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 433, 1533)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4189)
[M::mem_pestat] mean and std.dev: (932.64, 977.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5517)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (116, 157, 213)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 407)
[M::mem_pestat] mean and std.dev: (169.43, 70.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 504)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (344, 777, 859)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1889)
[M::mem_pestat] mean and std.dev: (507.64, 289.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2404)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 374, 927)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2425)
[M::mem_pestat] mean and std.dev: (499.14, 461.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3174)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 752740 sequences (100000179 bp) in 1.730 CPU sec, 1.738 real sec...
[M::mem_process_seqs] Processed 755686 reads in 188.637 CPU sec, 5.995 real sec
[M::mem_process_seqs] Processed 754102 reads in 123.949 CPU sec, 3.933 real sec
sorting block 2, #reads = 1118745 mem = 536876928 peak = 857812992
[M::process] read 752356 sequences (100000292 bp) in 2.211 CPU sec, 2.357 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 303561, 17, 21)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 324, 926)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2468)
[M::mem_pestat] mean and std.dev: (454.21, 443.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3239)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (116, 158, 214)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 410)
[M::mem_pestat] mean and std.dev: (170.45, 71.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 508)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (479, 675, 1070)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2252)
[M::mem_pestat] mean and std.dev: (642.56, 416.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2843)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 325, 1430)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3908)
[M::mem_pestat] mean and std.dev: (721.37, 803.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5147)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 751880 sequences (100000198 bp) in 1.677 CPU sec, 1.699 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 303001, 16, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 264, 791)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2019)
[M::mem_pestat] mean and std.dev: (431.92, 396.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2633)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (116, 158, 214)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 410)
[M::mem_pestat] mean and std.dev: (170.52, 71.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 508)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 500, 602)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1404)
[M::mem_pestat] mean and std.dev: (394.43, 314.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1805)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 392, 903)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2375)
[M::mem_pestat] mean and std.dev: (505.28, 449.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3111)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 753192 reads in 180.096 CPU sec, 5.748 real sec
[M::mem_process_seqs] Processed 752740 reads in 121.324 CPU sec, 3.890 real sec
sorting block 3, #reads = 1116269 mem = 536878516 peak = 857812992
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 302807, 26, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (137, 229, 410)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 956)
[M::mem_pestat] mean and std.dev: (234.84, 177.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1229)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 158, 216)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 414)
[M::mem_pestat] mean and std.dev: (171.32, 72.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 513)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (140, 1182, 1876)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5348)
[M::mem_pestat] mean and std.dev: (1064.91, 1139.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7084)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 510, 1122)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2924)
[M::mem_pestat] mean and std.dev: (810.72, 817.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4079)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 750958 sequences (100000026 bp) in 2.628 CPU sec, 2.740 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 302930, 20, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 264, 1020)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2766)
[M::mem_pestat] mean and std.dev: (447.23, 529.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3639)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 158, 215)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 411)
[M::mem_pestat] mean and std.dev: (171.12, 71.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 509)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 788, 1326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3618)
[M::mem_pestat] mean and std.dev: (780.26, 708.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4764)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 246, 430)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 860)
[M::mem_pestat] mean and std.dev: (272.11, 144.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1075)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 750026 sequences (100000254 bp) in 1.988 CPU sec, 1.996 real sec...
[M::mem_process_seqs] Processed 752356 reads in 188.838 CPU sec, 6.035 real sec
sorting block 4, #reads = 1118660 mem = 536878052 peak = 857812992
[M::mem_process_seqs] Processed 751880 reads in 125.068 CPU sec, 3.988 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 302716, 20, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 292, 385)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 831)
[M::mem_pestat] mean and std.dev: (258.89, 158.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1054)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 159, 216)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 414)
[M::mem_pestat] mean and std.dev: (171.76, 72.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 513)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (233, 920, 2749)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7781)
[M::mem_pestat] mean and std.dev: (1238.26, 1481.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10297)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 333, 809)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2025)
[M::mem_pestat] mean and std.dev: (474.62, 403.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2633)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 5, #reads = 1117508 mem = 536879949 peak = 857812992
[M::process] read 749732 sequences (100000186 bp) in 2.595 CPU sec, 2.829 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (15, 302172, 18, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 210, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 632)
[M::mem_pestat] mean and std.dev: (215.93, 88.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 787)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 160, 217)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 415)
[M::mem_pestat] mean and std.dev: (172.33, 72.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 514)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (288, 704, 1326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3402)
[M::mem_pestat] mean and std.dev: (623.80, 540.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4440)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 341, 1098)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2892)
[M::mem_pestat] mean and std.dev: (761.97, 798.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3955)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 749304 sequences (100000044 bp) in 2.022 CPU sec, 2.029 real sec...
[M::mem_process_seqs] Processed 750958 reads in 192.985 CPU sec, 6.185 real sec
[M::mem_process_seqs] Processed 750026 reads in 129.982 CPU sec, 4.146 real sec
sorting block 6, #reads = 1115942 mem = 536877654 peak = 857812992
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 302393, 23, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 276, 1814)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5086)
[M::mem_pestat] mean and std.dev: (709.77, 747.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6722)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 159, 217)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 415)
[M::mem_pestat] mean and std.dev: (172.33, 72.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 514)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (86, 281, 1164)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3320)
[M::mem_pestat] mean and std.dev: (581.86, 690.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4398)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 282, 913)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2359)
[M::mem_pestat] mean and std.dev: (443.39, 342.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3082)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 749596 sequences (100000095 bp) in 3.023 CPU sec, 3.347 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 301959, 14, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 227, 611)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1539)
[M::mem_pestat] mean and std.dev: (263.76, 189.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2003)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 160, 216)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 412)
[M::mem_pestat] mean and std.dev: (172.22, 71.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 510)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (380, 745, 1525)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3815)
[M::mem_pestat] mean and std.dev: (851.00, 877.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4960)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 215, 301)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 561)
[M::mem_pestat] mean and std.dev: (236.92, 107.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 691)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 749772 sequences (100000188 bp) in 2.082 CPU sec, 2.089 real sec...
[M::mem_process_seqs] Processed 749732 reads in 192.954 CPU sec, 6.183 real sec
[M::mem_process_seqs] Processed 749304 reads in 129.180 CPU sec, 4.144 real sec
sorting block 7, #reads = 1116123 mem = 536882936 peak = 857812992
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 302008, 25, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 834, 1697)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4669)
[M::mem_pestat] mean and std.dev: (918.82, 795.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6155)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 160, 216)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 412)
[M::mem_pestat] mean and std.dev: (172.26, 71.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 510)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 504, 1012)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2640)
[M::mem_pestat] mean and std.dev: (676.54, 718.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3550)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 656, 1629)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4399)
[M::mem_pestat] mean and std.dev: (869.69, 770.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5784)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 749056 sequences (100000139 bp) in 2.328 CPU sec, 2.642 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 301567, 16, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (278, 431, 1736)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4652)
[M::mem_pestat] mean and std.dev: (1007.36, 1121.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6110)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 159, 216)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 412)
[M::mem_pestat] mean and std.dev: (171.97, 71.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 510)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (247, 584, 951)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2359)
[M::mem_pestat] mean and std.dev: (579.13, 372.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3063)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 244, 575)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1401)
[M::mem_pestat] mean and std.dev: (305.55, 200.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1814)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 748598 sequences (100000107 bp) in 2.124 CPU sec, 2.128 real sec...
[M::mem_process_seqs] Processed 749596 reads in 195.158 CPU sec, 6.288 real sec
sorting block 8, #reads = 1114506 mem = 536880420 peak = 857812992
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 301746, 19, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 293, 538)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1274)
[M::mem_pestat] mean and std.dev: (322.90, 241.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1642)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 160, 217)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 415)
[M::mem_pestat] mean and std.dev: (172.56, 71.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 514)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (229, 435, 1236)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3250)
[M::mem_pestat] mean and std.dev: (662.44, 696.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4257)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 201, 543)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1361)
[M::mem_pestat] mean and std.dev: (230.27, 160.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1770)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 749056 reads in 108.937 CPU sec, 3.467 real sec
[M::process] read 748432 sequences (100000285 bp) in 2.715 CPU sec, 2.737 real sec...
sorting block 9, #reads = 1114688 mem = 536877771 peak = 857812992
[M::mem_process_seqs] Processed 749772 reads in 300.640 CPU sec, 9.613 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 301869, 20, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (135, 290, 1143)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3159)
[M::mem_pestat] mean and std.dev: (581.68, 664.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4167)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 160, 217)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 415)
[M::mem_pestat] mean and std.dev: (172.83, 72.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 514)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (87, 1055, 3086)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9084)
[M::mem_pestat] mean and std.dev: (1591.90, 2077.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12083)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 404, 3050)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8744)
[M::mem_pestat] mean and std.dev: (1274.08, 1536.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11591)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 747774 sequences (100000001 bp) in 3.004 CPU sec, 3.261 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 301377, 27, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 279, 765)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1995)
[M::mem_pestat] mean and std.dev: (398.33, 392.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2610)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 160, 218)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 418)
[M::mem_pestat] mean and std.dev: (173.52, 72.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 518)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (243, 560, 1780)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4854)
[M::mem_pestat] mean and std.dev: (1048.78, 979.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6391)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 246, 953)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2537)
[M::mem_pestat] mean and std.dev: (416.90, 484.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3329)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 748598 reads in 218.153 CPU sec, 6.964 real sec
sorting block 10, #reads = 1113941 mem = 536884550 peak = 857812992
[M::mem_process_seqs] Processed 748432 reads in 133.081 CPU sec, 4.224 real sec
[M::process] read 747742 sequences (100000145 bp) in 2.443 CPU sec, 2.585 real sec...
sorting block 11, #reads = 1113760 mem = 536881636 peak = 857812992
[M::process] read 746860 sequences (100000119 bp) in 2.986 CPU sec, 3.295 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 301463, 20, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 389, 866)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2222)
[M::mem_pestat] mean and std.dev: (518.20, 443.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2900)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (119, 161, 220)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 422)
[M::mem_pestat] mean and std.dev: (174.64, 73.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 523)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 485, 2959)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8485)
[M::mem_pestat] mean and std.dev: (1323.20, 1951.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11248)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 312, 783)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2053)
[M::mem_pestat] mean and std.dev: (452.49, 413.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2688)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 747742 reads in 117.219 CPU sec, 3.743 real sec
[M::process] read 746948 sequences (100000162 bp) in 2.704 CPU sec, 2.878 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 301339, 28, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 199, 469)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1105)
[M::mem_pestat] mean and std.dev: (253.94, 184.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1423)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (119, 161, 219)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 419)
[M::mem_pestat] mean and std.dev: (174.21, 73.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 519)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (110, 327, 1109)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3107)
[M::mem_pestat] mean and std.dev: (603.93, 686.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4106)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 220, 765)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1971)
[M::mem_pestat] mean and std.dev: (416.20, 420.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2574)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 301594, 25, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 346, 1138)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3086)
[M::mem_pestat] mean and std.dev: (668.74, 635.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4060)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (119, 162, 220)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 422)
[M::mem_pestat] mean and std.dev: (174.97, 73.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 523)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (125, 286, 1534)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4352)
[M::mem_pestat] mean and std.dev: (710.58, 916.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5761)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 277, 808)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2108)
[M::mem_pestat] mean and std.dev: (496.58, 544.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2758)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 747774 reads in 310.247 CPU sec, 9.954 real sec
sorting block 12, #reads = 1114471 mem = 536878315 peak = 857812992
[M::mem_process_seqs] Processed 746860 reads in 154.521 CPU sec, 4.946 real sec
[M::process] read 746434 sequences (100000259 bp) in 2.583 CPU sec, 2.683 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 301194, 16, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (284, 555, 921)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2195)
[M::mem_pestat] mean and std.dev: (542.29, 387.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2832)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (119, 162, 220)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 422)
[M::mem_pestat] mean and std.dev: (174.99, 73.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 523)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 355, 742)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1806)
[M::mem_pestat] mean and std.dev: (405.73, 320.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2338)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 250, 430)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 876)
[M::mem_pestat] mean and std.dev: (275.77, 161.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1099)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 13, #reads = 1113565 mem = 536879005 peak = 857812992
[M::process] read 752216 sequences (100000099 bp) in 2.662 CPU sec, 2.921 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 300660, 25, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 216, 971)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2579)
[M::mem_pestat] mean and std.dev: (493.50, 552.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3383)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (119, 162, 221)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 425)
[M::mem_pestat] mean and std.dev: (175.59, 74.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 527)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 536, 837)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2171)
[M::mem_pestat] mean and std.dev: (473.30, 335.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2838)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 457, 852)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2166)
[M::mem_pestat] mean and std.dev: (505.60, 368.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2823)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 746948 reads in 200.541 CPU sec, 6.446 real sec
[M::process] read 758788 sequences (100000109 bp) in 2.129 CPU sec, 2.260 real sec...
[M::mem_process_seqs] Processed 746434 reads in 131.074 CPU sec, 4.164 real sec
sorting block 14, #reads = 1113307 mem = 536877950 peak = 857812992
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 302598, 16, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 358, 882)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2276)
[M::mem_pestat] mean and std.dev: (547.40, 544.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2973)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 158, 215)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 411)
[M::mem_pestat] mean and std.dev: (171.21, 71.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 509)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (93, 395, 1717)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4965)
[M::mem_pestat] mean and std.dev: (681.53, 894.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6589)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 299, 807)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2045)
[M::mem_pestat] mean and std.dev: (518.65, 477.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2664)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 758268 sequences (100000114 bp) in 3.252 CPU sec, 3.491 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 305365, 33, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 242, 1406)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3890)
[M::mem_pestat] mean and std.dev: (811.83, 1026.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5132)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (114, 154, 209)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 399)
[M::mem_pestat] mean and std.dev: (166.49, 69.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 494)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 260, 848)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2248)
[M::mem_pestat] mean and std.dev: (542.39, 636.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3087)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 280, 1177)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3139)
[M::mem_pestat] mean and std.dev: (665.00, 731.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4120)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 752216 reads in 197.737 CPU sec, 6.328 real sec
[M::process] read 757626 sequences (100000112 bp) in 2.288 CPU sec, 2.332 real sec...
[M::mem_process_seqs] Processed 758788 reads in 130.333 CPU sec, 4.150 real sec
sorting block 15, #reads = 1111677 mem = 536880919 peak = 857812992
[M::process] read 756746 sequences (100000270 bp) in 3.123 CPU sec, 3.360 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 305011, 8, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 442, 1306)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3622)
[M::mem_pestat] mean and std.dev: (695.64, 711.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4780)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (115, 155, 210)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 400)
[M::mem_pestat] mean and std.dev: (167.34, 69.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 495)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 326, 1023)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2709)
[M::mem_pestat] mean and std.dev: (590.93, 604.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3552)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 757626 reads in 109.410 CPU sec, 3.467 real sec
sorting block 16, #reads = 1120963 mem = 536877020 peak = 857812992
[M::process] read 755910 sequences (100000147 bp) in 2.486 CPU sec, 2.596 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 304959, 18, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 203, 580)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1372)
[M::mem_pestat] mean and std.dev: (266.27, 174.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1768)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (114, 154, 210)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 402)
[M::mem_pestat] mean and std.dev: (167.00, 69.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 498)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (89, 264, 521)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1385)
[M::mem_pestat] mean and std.dev: (261.06, 250.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1817)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (142, 335, 1024)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2788)
[M::mem_pestat] mean and std.dev: (635.64, 626.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3670)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 304543, 28, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 323, 513)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1243)
[M::mem_pestat] mean and std.dev: (280.97, 200.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1608)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (115, 155, 211)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 403)
[M::mem_pestat] mean and std.dev: (168.01, 70.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 499)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (412, 891, 2074)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5398)
[M::mem_pestat] mean and std.dev: (1084.92, 943.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7060)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 313, 569)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1349)
[M::mem_pestat] mean and std.dev: (338.76, 227.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1739)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 758268 reads in 301.642 CPU sec, 9.704 real sec
[M::mem_process_seqs] Processed 756746 reads in 151.332 CPU sec, 4.866 real sec
[M::process] read 754818 sequences (100000042 bp) in 2.526 CPU sec, 2.640 real sec...
sorting block 17, #reads = 1120998 mem = 536879356 peak = 857812992
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 304695, 9, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (122, 279, 499)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1253)
[M::mem_pestat] mean and std.dev: (233.41, 148.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1630)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (115, 156, 212)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 406)
[M::mem_pestat] mean and std.dev: (168.69, 70.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 503)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 417, 1286)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3498)
[M::mem_pestat] mean and std.dev: (689.07, 725.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4604)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 753682 sequences (100000099 bp) in 3.098 CPU sec, 3.355 real sec...
sorting block 18, #reads = 1122025 mem = 536877811 peak = 857812992
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 304169, 30, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 194, 523)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1269)
[M::mem_pestat] mean and std.dev: (331.81, 332.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1663)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (116, 156, 213)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 407)
[M::mem_pestat] mean and std.dev: (169.50, 71.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 504)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (106, 462, 1212)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3424)
[M::mem_pestat] mean and std.dev: (750.21, 935.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4530)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 336, 798)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2062)
[M::mem_pestat] mean and std.dev: (485.07, 461.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2694)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 755910 reads in 191.610 CPU sec, 6.219 real sec
[M::mem_process_seqs] Processed 754818 reads in 129.572 CPU sec, 4.210 real sec
[M::process] read 752936 sequences (100000073 bp) in 2.204 CPU sec, 2.350 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 303315, 23, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 262, 825)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2131)
[M::mem_pestat] mean and std.dev: (399.42, 408.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2784)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (116, 157, 214)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 410)
[M::mem_pestat] mean and std.dev: (170.15, 71.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 508)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (230, 1115, 2256)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6308)
[M::mem_pestat] mean and std.dev: (1426.09, 1305.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8334)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 283, 743)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1911)
[M::mem_pestat] mean and std.dev: (441.53, 393.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2495)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 19, #reads = 1120291 mem = 536887604 peak = 857812992
[M::process] read 752586 sequences (100000040 bp) in 3.184 CPU sec, 3.499 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (22, 303075, 18, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 538, 887)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2247)
[M::mem_pestat] mean and std.dev: (526.11, 483.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2927)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (116, 157, 215)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 413)
[M::mem_pestat] mean and std.dev: (170.75, 72.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 512)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (225, 345, 1306)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3468)
[M::mem_pestat] mean and std.dev: (739.89, 827.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4549)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 328, 578)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1284)
[M::mem_pestat] mean and std.dev: (332.83, 187.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1637)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 753682 reads in 190.717 CPU sec, 6.116 real sec
[M::mem_process_seqs] Processed 752936 reads in 128.371 CPU sec, 4.078 real sec
[M::process] read 752678 sequences (100000199 bp) in 2.454 CPU sec, 2.560 real sec...
sorting block 20, #reads = 1119528 mem = 536879168 peak = 857812992
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 302670, 30, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 280, 792)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2038)
[M::mem_pestat] mean and std.dev: (368.97, 383.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2661)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (116, 158, 215)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 413)
[M::mem_pestat] mean and std.dev: (170.86, 71.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 512)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (128, 267, 1470)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4154)
[M::mem_pestat] mean and std.dev: (607.63, 729.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5496)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 322, 805)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2045)
[M::mem_pestat] mean and std.dev: (376.21, 286.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2665)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 752180 sequences (100000155 bp) in 3.090 CPU sec, 3.439 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 302395, 36, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (234, 421, 918)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2286)
[M::mem_pestat] mean and std.dev: (536.12, 479.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2970)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (116, 158, 215)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 413)
[M::mem_pestat] mean and std.dev: (170.68, 71.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 512)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 561, 1142)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3132)
[M::mem_pestat] mean and std.dev: (496.16, 500.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4127)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 379, 1011)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2657)
[M::mem_pestat] mean and std.dev: (546.06, 557.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3480)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 752586 reads in 193.779 CPU sec, 6.258 real sec
[M::mem_process_seqs] Processed 752678 reads in 129.541 CPU sec, 4.125 real sec
sorting block 21, #reads = 1117411 mem = 536880084 peak = 857812992
[M::process] read 751120 sequences (100000089 bp) in 2.295 CPU sec, 2.464 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 302759, 18, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 409, 940)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2434)
[M::mem_pestat] mean and std.dev: (487.16, 431.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3181)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 158, 215)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 411)
[M::mem_pestat] mean and std.dev: (170.84, 71.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 509)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (82, 230, 291)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 709)
[M::mem_pestat] mean and std.dev: (175.36, 91.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 918)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 300, 571)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1359)
[M::mem_pestat] mean and std.dev: (381.67, 279.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1753)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 22, #reads = 1116871 mem = 536878252 peak = 857812992
[M::process] read 750778 sequences (100000272 bp) in 3.280 CPU sec, 3.519 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 302483, 19, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 189, 717)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1855)
[M::mem_pestat] mean and std.dev: (360.18, 386.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2424)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 159, 216)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 414)
[M::mem_pestat] mean and std.dev: (171.63, 72.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 513)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (520, 900, 1894)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4642)
[M::mem_pestat] mean and std.dev: (994.00, 666.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6016)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 517, 609)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1429)
[M::mem_pestat] mean and std.dev: (372.87, 221.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1839)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 752180 reads in 197.083 CPU sec, 6.330 real sec
[M::mem_process_seqs] Processed 751120 reads in 132.160 CPU sec, 4.227 real sec
[M::process] read 750100 sequences (100000172 bp) in 2.367 CPU sec, 2.568 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 302397, 19, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (146, 257, 877)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2339)
[M::mem_pestat] mean and std.dev: (460.25, 454.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3070)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 159, 216)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 414)
[M::mem_pestat] mean and std.dev: (171.72, 71.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 513)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (122, 551, 1050)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2906)
[M::mem_pestat] mean and std.dev: (556.50, 552.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3834)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 231, 908)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2374)
[M::mem_pestat] mean and std.dev: (430.14, 423.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3107)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 23, #reads = 1116126 mem = 536879083 peak = 857812992
[M::process] read 749834 sequences (100000147 bp) in 3.404 CPU sec, 3.813 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 301925, 26, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 387, 1358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3720)
[M::mem_pestat] mean and std.dev: (590.03, 711.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4901)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 159, 216)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 412)
[M::mem_pestat] mean and std.dev: (171.99, 71.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 510)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (94, 169, 471)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1225)
[M::mem_pestat] mean and std.dev: (159.10, 140.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1602)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 193, 650)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1634)
[M::mem_pestat] mean and std.dev: (270.93, 187.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2126)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 750778 reads in 197.850 CPU sec, 6.370 real sec
[M::mem_process_seqs] Processed 750100 reads in 134.830 CPU sec, 4.298 real sec
[M::process] read 749592 sequences (100000098 bp) in 2.460 CPU sec, 2.602 real sec...
sorting block 24, #reads = 1115411 mem = 536878561 peak = 857812992
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 301769, 18, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (129, 301, 778)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2076)
[M::mem_pestat] mean and std.dev: (431.00, 412.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2725)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 159, 216)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 412)
[M::mem_pestat] mean and std.dev: (172.12, 71.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 510)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (236, 303, 733)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1727)
[M::mem_pestat] mean and std.dev: (395.56, 289.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2224)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 313, 818)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2152)
[M::mem_pestat] mean and std.dev: (476.85, 452.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2819)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 749184 sequences (100000235 bp) in 2.934 CPU sec, 3.436 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 302085, 25, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 441, 1597)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4451)
[M::mem_pestat] mean and std.dev: (840.74, 825.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5878)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 160, 217)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 415)
[M::mem_pestat] mean and std.dev: (172.66, 72.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 514)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (104, 501, 1324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3764)
[M::mem_pestat] mean and std.dev: (650.78, 749.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4984)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (269, 623, 1442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3788)
[M::mem_pestat] mean and std.dev: (841.16, 784.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4961)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 749834 reads in 198.640 CPU sec, 6.424 real sec
[M::mem_process_seqs] Processed 749592 reads in 135.508 CPU sec, 4.336 real sec
sorting block 25, #reads = 1114908 mem = 536881412 peak = 857812992
[M::process] read 748944 sequences (100000063 bp) in 2.568 CPU sec, 2.689 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 301337, 25, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 298, 759)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1977)
[M::mem_pestat] mean and std.dev: (472.74, 497.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2586)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 160, 217)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 415)
[M::mem_pestat] mean and std.dev: (172.77, 72.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 514)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (276, 483, 1151)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2901)
[M::mem_pestat] mean and std.dev: (753.88, 736.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3776)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 182, 934)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2510)
[M::mem_pestat] mean and std.dev: (491.85, 600.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3298)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 26, #reads = 1115030 mem = 536884205 peak = 857812992
[M::process] read 748948 sequences (100000205 bp) in 3.293 CPU sec, 3.620 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 301437, 24, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 325, 733)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1859)
[M::mem_pestat] mean and std.dev: (497.78, 432.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2422)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 160, 217)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 415)
[M::mem_pestat] mean and std.dev: (172.79, 72.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 514)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (117, 204, 654)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1728)
[M::mem_pestat] mean and std.dev: (327.05, 305.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2265)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 244, 690)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1768)
[M::mem_pestat] mean and std.dev: (309.18, 232.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2307)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 749184 reads in 196.818 CPU sec, 6.427 real sec
[M::mem_process_seqs] Processed 748944 reads in 134.839 CPU sec, 4.402 real sec
[M::process] read 748692 sequences (100000071 bp) in 2.126 CPU sec, 2.305 real sec...
sorting block 27, #reads = 1113600 mem = 536877668 peak = 857812992
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 301758, 28, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 246, 965)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2597)
[M::mem_pestat] mean and std.dev: (530.82, 553.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3413)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 160, 217)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 415)
[M::mem_pestat] mean and std.dev: (172.92, 72.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 514)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (91, 340, 534)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1420)
[M::mem_pestat] mean and std.dev: (335.58, 281.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1863)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 221, 556)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1316)
[M::mem_pestat] mean and std.dev: (310.47, 232.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1696)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 748110 sequences (100000113 bp) in 3.225 CPU sec, 3.510 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 301736, 22, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 394, 807)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2095)
[M::mem_pestat] mean and std.dev: (479.25, 391.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2739)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 160, 218)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 418)
[M::mem_pestat] mean and std.dev: (173.30, 72.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 518)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 594, 931)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2353)
[M::mem_pestat] mean and std.dev: (551.65, 398.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3064)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 535, 1185)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3195)
[M::mem_pestat] mean and std.dev: (648.94, 598.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4200)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 748948 reads in 198.092 CPU sec, 6.348 real sec
[M::process] read 748446 sequences (100000209 bp) in 2.214 CPU sec, 2.329 real sec...
[M::mem_process_seqs] Processed 748692 reads in 133.989 CPU sec, 4.262 real sec
sorting block 28, #reads = 1114163 mem = 536884521 peak = 857812992
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 301620, 28, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 288, 639)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1601)
[M::mem_pestat] mean and std.dev: (327.41, 256.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2082)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 161, 218)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 418)
[M::mem_pestat] mean and std.dev: (173.65, 72.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 518)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (529, 1406, 2380)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6082)
[M::mem_pestat] mean and std.dev: (1417.19, 1139.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7933)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 491, 850)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2146)
[M::mem_pestat] mean and std.dev: (545.41, 430.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2794)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 748990 sequences (100000274 bp) in 3.458 CPU sec, 3.832 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 300888, 13, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 189, 860)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2286)
[M::mem_pestat] mean and std.dev: (421.50, 486.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2999)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 161, 218)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 418)
[M::mem_pestat] mean and std.dev: (173.49, 72.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 518)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (125, 486, 1074)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2972)
[M::mem_pestat] mean and std.dev: (454.27, 367.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3921)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 180, 452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1052)
[M::mem_pestat] mean and std.dev: (278.46, 222.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1352)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 748110 reads in 196.067 CPU sec, 6.338 real sec
sorting block 29, #reads = 1114233 mem = 536880759 peak = 857812992
[M::mem_process_seqs] Processed 748446 reads in 132.941 CPU sec, 4.251 real sec
[M::process] read 758814 sequences (100000001 bp) in 2.215 CPU sec, 2.305 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 301427, 17, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 293, 605)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1435)
[M::mem_pestat] mean and std.dev: (380.83, 289.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1850)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 160, 217)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 415)
[M::mem_pestat] mean and std.dev: (172.80, 72.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 514)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 574, 2586)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7354)
[M::mem_pestat] mean and std.dev: (1256.82, 1555.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9738)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 524, 1459)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4041)
[M::mem_pestat] mean and std.dev: (854.37, 1015.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5332)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 30, #reads = 1113509 mem = 536879775 peak = 857812992
[M::process] read 759630 sequences (100000105 bp) in 3.051 CPU sec, 3.390 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 304404, 14, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 614, 1716)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4800)
[M::mem_pestat] mean and std.dev: (843.14, 792.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6342)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (114, 154, 209)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 399)
[M::mem_pestat] mean and std.dev: (166.49, 69.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 494)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (135, 377, 881)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2373)
[M::mem_pestat] mean and std.dev: (459.08, 427.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3119)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 310, 606)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1370)
[M::mem_pestat] mean and std.dev: (401.26, 329.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1752)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 748990 reads in 201.143 CPU sec, 6.482 real sec
[M::process] read 759244 sequences (100000234 bp) in 2.183 CPU sec, 2.270 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 305409, 27, 24)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 437, 965)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2585)
[M::mem_pestat] mean and std.dev: (498.03, 400.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3395)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (114, 153, 209)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 399)
[M::mem_pestat] mean and std.dev: (166.16, 69.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 494)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 510, 791)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2035)
[M::mem_pestat] mean and std.dev: (519.84, 464.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2657)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 187, 935)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2491)
[M::mem_pestat] mean and std.dev: (451.18, 553.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3269)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 759630 reads in 112.687 CPU sec, 3.631 real sec
[M::process] read 757990 sequences (100000065 bp) in 2.578 CPU sec, 2.631 real sec...
sorting block 31, #reads = 1111628 mem = 536878883 peak = 857812992
[M::mem_process_seqs] Processed 758814 reads in 293.436 CPU sec, 9.434 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 305262, 21, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 314, 924)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2426)
[M::mem_pestat] mean and std.dev: (516.81, 465.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3177)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (114, 154, 208)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 396)
[M::mem_pestat] mean and std.dev: (166.03, 68.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 490)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (391, 604, 946)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2056)
[M::mem_pestat] mean and std.dev: (585.53, 378.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2611)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (232, 336, 1033)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2635)
[M::mem_pestat] mean and std.dev: (567.37, 639.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3436)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 32, #reads = 1119177 mem = 536881922 peak = 857812992
[M::process] read 757014 sequences (100000082 bp) in 3.263 CPU sec, 3.678 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 304722, 20, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (142, 290, 722)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1882)
[M::mem_pestat] mean and std.dev: (470.50, 425.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2462)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (114, 155, 210)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 402)
[M::mem_pestat] mean and std.dev: (167.27, 69.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 498)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 875, 2703)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7747)
[M::mem_pestat] mean and std.dev: (1246.80, 1057.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10269)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 305, 1306)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3580)
[M::mem_pestat] mean and std.dev: (602.84, 749.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4717)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 759244 reads in 221.833 CPU sec, 7.171 real sec
[M::mem_process_seqs] Processed 757990 reads in 134.275 CPU sec, 4.344 real sec
[M::process] read 755338 sequences (100000042 bp) in 2.299 CPU sec, 2.466 real sec...
sorting block 33, #reads = 1121348 mem = 536882284 peak = 857812992
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 304563, 28, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (431, 781, 2030)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5228)
[M::mem_pestat] mean and std.dev: (995.00, 873.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6827)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (115, 155, 211)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 403)
[M::mem_pestat] mean and std.dev: (167.98, 70.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 499)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (300, 953, 1287)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3261)
[M::mem_pestat] mean and std.dev: (907.04, 757.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4248)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 167, 443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1027)
[M::mem_pestat] mean and std.dev: (218.27, 140.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1319)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 754384 sequences (100000179 bp) in 2.997 CPU sec, 3.288 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 303857, 12, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 432, 1206)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3284)
[M::mem_pestat] mean and std.dev: (710.51, 763.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4323)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (115, 156, 214)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 412)
[M::mem_pestat] mean and std.dev: (169.78, 71.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 511)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 248, 1413)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3889)
[M::mem_pestat] mean and std.dev: (280.50, 390.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5127)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (124, 292, 506)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1270)
[M::mem_pestat] mean and std.dev: (290.40, 217.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1652)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 757014 reads in 194.988 CPU sec, 6.298 real sec
[M::mem_process_seqs] Processed 755338 reads in 130.628 CPU sec, 4.174 real sec
[M::process] read 753346 sequences (100000274 bp) in 2.642 CPU sec, 2.827 real sec...
sorting block 34, #reads = 1118992 mem = 536878235 peak = 857812992
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 303870, 25, 24)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (142, 210, 687)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1777)
[M::mem_pestat] mean and std.dev: (339.41, 276.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2322)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (116, 157, 214)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 410)
[M::mem_pestat] mean and std.dev: (170.20, 71.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 508)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 468, 2119)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5991)
[M::mem_pestat] mean and std.dev: (1509.32, 1982.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9438)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 303, 383)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 873)
[M::mem_pestat] mean and std.dev: (275.71, 162.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1118)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 752402 sequences (100000250 bp) in 3.093 CPU sec, 3.370 real sec...
sorting block 35, #reads = 1119465 mem = 536878741 peak = 857812992
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 303649, 32, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 301, 2131)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6083)
[M::mem_pestat] mean and std.dev: (930.80, 1131.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8059)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (116, 157, 215)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 413)
[M::mem_pestat] mean and std.dev: (170.67, 72.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 512)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (642, 1710, 3065)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7911)
[M::mem_pestat] mean and std.dev: (1896.41, 1691.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10334)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 390, 881)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2333)
[M::mem_pestat] mean and std.dev: (518.20, 506.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3059)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 754384 reads in 193.029 CPU sec, 6.228 real sec
[M::mem_process_seqs] Processed 753346 reads in 130.358 CPU sec, 4.186 real sec
[M::process] read 752818 sequences (100000149 bp) in 2.655 CPU sec, 2.846 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 302866, 24, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (143, 209, 555)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1379)
[M::mem_pestat] mean and std.dev: (303.14, 237.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1791)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 158, 216)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 414)
[M::mem_pestat] mean and std.dev: (171.49, 72.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 513)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 673, 1926)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5334)
[M::mem_pestat] mean and std.dev: (923.91, 1168.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7038)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 281, 514)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1132)
[M::mem_pestat] mean and std.dev: (350.25, 240.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1441)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 36, #reads = 1118718 mem = 536878368 peak = 857812992
[M::process] read 752024 sequences (100000088 bp) in 3.031 CPU sec, 3.422 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 303379, 27, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 335, 808)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2060)
[M::mem_pestat] mean and std.dev: (406.29, 354.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2686)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (116, 158, 216)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 416)
[M::mem_pestat] mean and std.dev: (171.42, 72.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 516)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (310, 645, 1074)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2602)
[M::mem_pestat] mean and std.dev: (696.04, 511.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3366)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 328, 449)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1015)
[M::mem_pestat] mean and std.dev: (302.79, 154.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1298)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 752402 reads in 194.807 CPU sec, 6.286 real sec
[M::mem_process_seqs] Processed 752818 reads in 133.466 CPU sec, 4.283 real sec
[M::process] read 751524 sequences (100000298 bp) in 2.664 CPU sec, 2.889 real sec...
sorting block 37, #reads = 1118173 mem = 536880982 peak = 857812992
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 303178, 13, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 408, 1133)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2991)
[M::mem_pestat] mean and std.dev: (655.23, 688.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3920)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 159, 216)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 414)
[M::mem_pestat] mean and std.dev: (171.64, 72.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 513)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (47, 156, 1002)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2912)
[M::mem_pestat] mean and std.dev: (371.92, 522.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3867)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 451, 818)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2074)
[M::mem_pestat] mean and std.dev: (558.22, 443.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2702)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 751584 sequences (100000031 bp) in 2.821 CPU sec, 3.188 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 303018, 19, 20)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (223, 522, 2079)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5791)
[M::mem_pestat] mean and std.dev: (1104.00, 1245.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7647)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 159, 217)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 417)
[M::mem_pestat] mean and std.dev: (172.13, 72.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 517)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 575, 7076)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 20866)
[M::mem_pestat] mean and std.dev: (2465.21, 3207.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 27761)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 204, 490)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1124)
[M::mem_pestat] mean and std.dev: (268.00, 210.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1441)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 752024 reads in 194.221 CPU sec, 6.283 real sec
[M::mem_process_seqs] Processed 751524 reads in 132.351 CPU sec, 4.249 real sec
sorting block 38, #reads = 1117212 mem = 536879379 peak = 857812992
[M::process] read 750566 sequences (100000161 bp) in 2.537 CPU sec, 2.734 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 302293, 16, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (136, 184, 738)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1942)
[M::mem_pestat] mean and std.dev: (474.94, 511.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2544)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 159, 215)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 411)
[M::mem_pestat] mean and std.dev: (171.35, 71.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 509)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (126, 525, 1790)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5118)
[M::mem_pestat] mean and std.dev: (678.86, 885.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6782)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 269, 615)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1533)
[M::mem_pestat] mean and std.dev: (300.45, 216.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1992)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 39, #reads = 1116775 mem = 536883807 peak = 857812992
[M::process] read 749780 sequences (100000093 bp) in 3.115 CPU sec, 3.501 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 302091, 22, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 331, 1399)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3903)
[M::mem_pestat] mean and std.dev: (656.45, 728.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5155)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 159, 216)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 414)
[M::mem_pestat] mean and std.dev: (172.17, 72.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 513)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (99, 703, 1166)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3300)
[M::mem_pestat] mean and std.dev: (824.59, 754.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4367)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 535, 1533)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4197)
[M::mem_pestat] mean and std.dev: (951.62, 1009.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5529)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 751584 reads in 196.207 CPU sec, 6.328 real sec
[M::mem_process_seqs] Processed 750566 reads in 133.867 CPU sec, 4.282 real sec
[M::process] read 749842 sequences (100000140 bp) in 2.514 CPU sec, 2.682 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 301928, 19, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (135, 379, 1029)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2817)
[M::mem_pestat] mean and std.dev: (571.34, 608.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3711)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 159, 216)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 412)
[M::mem_pestat] mean and std.dev: (172.13, 71.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 510)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 468, 1934)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5376)
[M::mem_pestat] mean and std.dev: (919.26, 896.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7097)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 321, 759)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1917)
[M::mem_pestat] mean and std.dev: (519.18, 483.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2496)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 40, #reads = 1116799 mem = 536877396 peak = 857812992
[M::process] read 749626 sequences (100000166 bp) in 3.171 CPU sec, 3.493 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 301639, 18, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 235, 384)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 858)
[M::mem_pestat] mean and std.dev: (278.89, 181.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1095)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 160, 217)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 415)
[M::mem_pestat] mean and std.dev: (172.61, 72.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 514)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 799, 1253)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3379)
[M::mem_pestat] mean and std.dev: (868.56, 729.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4442)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 215, 452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1010)
[M::mem_pestat] mean and std.dev: (273.44, 173.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1289)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 749780 reads in 197.945 CPU sec, 6.379 real sec
[M::mem_process_seqs] Processed 749842 reads in 133.769 CPU sec, 4.271 real sec
[M::process] read 748576 sequences (100000078 bp) in 2.461 CPU sec, 2.639 real sec...
sorting block 41, #reads = 1113933 mem = 536878084 peak = 857812992
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 301858, 23, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (143, 260, 589)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1481)
[M::mem_pestat] mean and std.dev: (339.65, 259.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1927)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 160, 217)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 415)
[M::mem_pestat] mean and std.dev: (172.76, 72.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 514)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (456, 987, 1878)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4722)
[M::mem_pestat] mean and std.dev: (1256.18, 1191.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6144)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 471, 1116)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2972)
[M::mem_pestat] mean and std.dev: (634.92, 651.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3900)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 748496 sequences (100000129 bp) in 3.146 CPU sec, 3.525 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 301482, 33, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (140, 184, 452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1076)
[M::mem_pestat] mean and std.dev: (187.71, 93.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1388)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 160, 218)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 418)
[M::mem_pestat] mean and std.dev: (173.34, 72.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 518)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 476, 1168)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3180)
[M::mem_pestat] mean and std.dev: (631.58, 657.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4186)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 226, 430)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1022)
[M::mem_pestat] mean and std.dev: (243.71, 140.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1318)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 749626 reads in 198.102 CPU sec, 6.386 real sec
[M::mem_process_seqs] Processed 748576 reads in 132.333 CPU sec, 4.226 real sec
sorting block 42, #reads = 1113721 mem = 536882068 peak = 857812992
[M::process] read 748934 sequences (100000033 bp) in 2.204 CPU sec, 2.268 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 301354, 14, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 259, 1129)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3023)
[M::mem_pestat] mean and std.dev: (589.75, 641.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3970)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 160, 218)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 418)
[M::mem_pestat] mean and std.dev: (173.33, 72.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 518)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 1496, 2066)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5790)
[M::mem_pestat] mean and std.dev: (1210.64, 1106.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7652)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (246, 522, 1168)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3012)
[M::mem_pestat] mean and std.dev: (647.19, 651.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3934)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 43, #reads = 1113364 mem = 536877612 peak = 857812992
[M::process] read 749470 sequences (100000235 bp) in 3.352 CPU sec, 3.877 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 301243, 31, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (134, 201, 1004)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2744)
[M::mem_pestat] mean and std.dev: (428.58, 520.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3614)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 160, 217)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 415)
[M::mem_pestat] mean and std.dev: (172.87, 72.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 514)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 751, 2331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6619)
[M::mem_pestat] mean and std.dev: (1132.97, 1213.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8763)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 267, 1272)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3540)
[M::mem_pestat] mean and std.dev: (626.41, 681.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4674)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 748496 reads in 200.135 CPU sec, 6.457 real sec
[M::mem_process_seqs] Processed 748934 reads in 136.658 CPU sec, 4.364 real sec
[M::process] read 748878 sequences (100000144 bp) in 2.547 CPU sec, 2.690 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 301381, 29, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 341, 1260)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3452)
[M::mem_pestat] mean and std.dev: (617.45, 695.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4548)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 160, 217)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 415)
[M::mem_pestat] mean and std.dev: (172.66, 72.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 514)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 345, 3509)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10181)
[M::mem_pestat] mean and std.dev: (1662.45, 2146.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13517)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 192, 265)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 501)
[M::mem_pestat] mean and std.dev: (199.61, 78.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 619)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 44, #reads = 1113454 mem = 536877634 peak = 857812992
[M::process] read 748566 sequences (100000095 bp) in 3.010 CPU sec, 3.363 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 301072, 33, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (144, 350, 1261)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3495)
[M::mem_pestat] mean and std.dev: (700.97, 807.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4612)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 160, 217)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 415)
[M::mem_pestat] mean and std.dev: (172.69, 72.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 514)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 618, 2835)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8071)
[M::mem_pestat] mean and std.dev: (1372.94, 1537.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10689)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 298, 731)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1757)
[M::mem_pestat] mean and std.dev: (332.95, 222.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2270)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 749470 reads in 198.872 CPU sec, 6.413 real sec
[M::mem_process_seqs] Processed 748878 reads in 134.188 CPU sec, 4.278 real sec
[M::process] read 753022 sequences (100000199 bp) in 2.538 CPU sec, 2.633 real sec...
sorting block 45, #reads = 1112794 mem = 536881351 peak = 857812992
[M::process] read 759056 sequences (100000084 bp) in 3.164 CPU sec, 3.621 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 303380, 19, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 491, 983)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2513)
[M::mem_pestat] mean and std.dev: (413.65, 256.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3278)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (116, 157, 214)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 410)
[M::mem_pestat] mean and std.dev: (170.16, 71.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 508)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (729, 1494, 2378)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5676)
[M::mem_pestat] mean and std.dev: (1709.22, 1462.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7558)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 235, 382)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 882)
[M::mem_pestat] mean and std.dev: (259.21, 153.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1132)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 753022 reads in 117.646 CPU sec, 3.757 real sec
sorting block 46, #reads = 1112765 mem = 536883016 peak = 857812992
[M::process] read 758388 sequences (100000297 bp) in 2.362 CPU sec, 2.479 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 301595, 11, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 226, 787)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2057)
[M::mem_pestat] mean and std.dev: (509.72, 546.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2695)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 160, 218)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 418)
[M::mem_pestat] mean and std.dev: (173.25, 72.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 518)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (490, 703, 936)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1828)
[M::mem_pestat] mean and std.dev: (726.55, 475.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2630)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 259, 1964)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5518)
[M::mem_pestat] mean and std.dev: (941.12, 1301.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7295)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 305309, 23, 24)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 329, 674)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1726)
[M::mem_pestat] mean and std.dev: (433.86, 369.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2252)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (114, 154, 210)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 402)
[M::mem_pestat] mean and std.dev: (166.73, 69.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 498)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (128, 634, 1546)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4382)
[M::mem_pestat] mean and std.dev: (915.48, 878.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5800)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (140, 217, 614)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1562)
[M::mem_pestat] mean and std.dev: (313.55, 326.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2036)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 748566 reads in 314.173 CPU sec, 10.101 real sec
[M::mem_process_seqs] Processed 759056 reads in 156.525 CPU sec, 4.989 real sec
[M::process] read 757454 sequences (100000038 bp) in 2.922 CPU sec, 3.077 real sec...
sorting block 47, #reads = 1113627 mem = 536888740 peak = 857812992
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 304701, 21, 22)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 329, 785)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2013)
[M::mem_pestat] mean and std.dev: (311.90, 270.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2627)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (114, 154, 210)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 402)
[M::mem_pestat] mean and std.dev: (167.25, 70.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 498)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (351, 859, 2593)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7077)
[M::mem_pestat] mean and std.dev: (1640.19, 1770.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9319)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 314, 670)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1640)
[M::mem_pestat] mean and std.dev: (414.00, 264.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2125)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 304772, 24, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 320, 1798)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5002)
[M::mem_pestat] mean and std.dev: (677.77, 730.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6604)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (114, 155, 211)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 405)
[M::mem_pestat] mean and std.dev: (167.90, 70.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 502)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (229, 302, 1095)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2827)
[M::mem_pestat] mean and std.dev: (491.55, 538.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3693)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 487, 1195)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3285)
[M::mem_pestat] mean and std.dev: (601.85, 592.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4330)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 756612 sequences (100000199 bp) in 3.759 CPU sec, 4.044 real sec...
[M::mem_process_seqs] Processed 758388 reads in 194.660 CPU sec, 6.286 real sec
sorting block 48, #reads = 1119668 mem = 536881180 peak = 857812992
[M::mem_process_seqs] Processed 757454 reads in 129.627 CPU sec, 4.152 real sec
[M::process] read 756140 sequences (100000116 bp) in 2.779 CPU sec, 3.001 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 304785, 20, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (138, 275, 1438)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4038)
[M::mem_pestat] mean and std.dev: (716.76, 876.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5338)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (115, 155, 212)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 406)
[M::mem_pestat] mean and std.dev: (168.31, 70.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 503)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 510, 973)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2481)
[M::mem_pestat] mean and std.dev: (545.16, 432.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3235)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 320, 839)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2137)
[M::mem_pestat] mean and std.dev: (437.10, 376.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2786)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 49, #reads = 1120185 mem = 536879039 peak = 857812992
[M::process] read 755552 sequences (100000051 bp) in 2.965 CPU sec, 3.305 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 303908, 19, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 339, 877)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2315)
[M::mem_pestat] mean and std.dev: (400.13, 344.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3034)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (115, 156, 212)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 406)
[M::mem_pestat] mean and std.dev: (168.70, 70.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 503)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (305, 481, 1134)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2792)
[M::mem_pestat] mean and std.dev: (762.42, 619.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3621)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 201, 594)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1464)
[M::mem_pestat] mean and std.dev: (298.66, 260.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1899)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 756612 reads in 197.115 CPU sec, 6.370 real sec
[M::mem_process_seqs] Processed 756140 reads in 133.505 CPU sec, 4.313 real sec
[M::process] read 754074 sequences (100000057 bp) in 3.167 CPU sec, 3.625 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 304417, 21, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (238, 560, 1328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3508)
[M::mem_pestat] mean and std.dev: (727.90, 657.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4598)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (115, 156, 213)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 409)
[M::mem_pestat] mean and std.dev: (169.22, 71.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 507)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (244, 688, 1879)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5149)
[M::mem_pestat] mean and std.dev: (836.32, 750.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6784)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 331, 826)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2142)
[M::mem_pestat] mean and std.dev: (456.10, 458.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2800)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 50, #reads = 1118966 mem = 536882242 peak = 857812992
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 303937, 11, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 210, 913)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2445)
[M::mem_pestat] mean and std.dev: (413.55, 478.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3211)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (116, 157, 214)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 410)
[M::mem_pestat] mean and std.dev: (170.12, 71.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 508)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (60, 183, 1494)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4362)
[M::mem_pestat] mean and std.dev: (536.64, 671.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5796)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 339, 837)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2097)
[M::mem_pestat] mean and std.dev: (499.00, 478.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2727)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 755552 reads in 196.321 CPU sec, 6.413 real sec
[M::process] read 753548 sequences (100000155 bp) in 3.183 CPU sec, 3.569 real sec...
[M::mem_process_seqs] Processed 754074 reads in 130.535 CPU sec, 4.220 real sec
sorting block 51, #reads = 1119144 mem = 536882647 peak = 857812992
[M::process] read 753558 sequences (100000154 bp) in 2.219 CPU sec, 2.372 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 303762, 13, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 269, 408)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 918)
[M::mem_pestat] mean and std.dev: (274.89, 158.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1173)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (116, 157, 215)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 413)
[M::mem_pestat] mean and std.dev: (170.66, 71.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 512)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (72, 261, 746)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2094)
[M::mem_pestat] mean and std.dev: (284.36, 247.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2768)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 414, 1214)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3320)
[M::mem_pestat] mean and std.dev: (685.00, 681.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4373)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 752862 sequences (100000257 bp) in 2.449 CPU sec, 2.761 real sec...
sorting block 52, #reads = 1119567 mem = 536879328 peak = 857812992
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 303358, 19, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (139, 271, 776)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2050)
[M::mem_pestat] mean and std.dev: (410.85, 366.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2687)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (116, 158, 215)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 413)
[M::mem_pestat] mean and std.dev: (170.86, 72.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 512)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (314, 576, 1608)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4196)
[M::mem_pestat] mean and std.dev: (585.81, 496.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5490)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 193, 491)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1161)
[M::mem_pestat] mean and std.dev: (225.92, 108.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1496)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 753548 reads in 195.992 CPU sec, 6.330 real sec
[M::mem_process_seqs] Processed 753558 reads in 132.098 CPU sec, 4.258 real sec
[M::process] read 753132 sequences (100000006 bp) in 2.383 CPU sec, 2.537 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 303076, 20, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 509, 996)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2602)
[M::mem_pestat] mean and std.dev: (511.14, 495.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3405)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (116, 158, 216)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 416)
[M::mem_pestat] mean and std.dev: (171.40, 72.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 516)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (57, 399, 1491)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4359)
[M::mem_pestat] mean and std.dev: (743.90, 772.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5793)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 222, 394)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 842)
[M::mem_pestat] mean and std.dev: (273.23, 165.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1066)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 53, #reads = 1119595 mem = 536879184 peak = 857812992
[M::process] read 753552 sequences (100000037 bp) in 3.003 CPU sec, 3.346 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 302739, 19, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 487, 835)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2201)
[M::mem_pestat] mean and std.dev: (432.18, 353.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2884)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (116, 158, 215)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 413)
[M::mem_pestat] mean and std.dev: (170.80, 71.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 512)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (444, 1363, 2377)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6243)
[M::mem_pestat] mean and std.dev: (1352.50, 1195.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8176)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 317, 466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1022)
[M::mem_pestat] mean and std.dev: (268.37, 140.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1300)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 752862 reads in 196.215 CPU sec, 6.344 real sec
[M::mem_process_seqs] Processed 753132 reads in 134.040 CPU sec, 4.294 real sec
[M::process] read 751852 sequences (100000139 bp) in 2.808 CPU sec, 2.925 real sec...
sorting block 54, #reads = 1119158 mem = 536879121 peak = 857812992
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 302802, 22, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 232, 1229)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3393)
[M::mem_pestat] mean and std.dev: (639.81, 761.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4475)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (116, 157, 213)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 407)
[M::mem_pestat] mean and std.dev: (169.74, 70.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 504)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (81, 335, 824)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2310)
[M::mem_pestat] mean and std.dev: (540.62, 607.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3053)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 392, 1325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3677)
[M::mem_pestat] mean and std.dev: (770.26, 838.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4853)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 750356 sequences (100000240 bp) in 2.863 CPU sec, 3.301 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 302759, 28, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 208, 940)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2480)
[M::mem_pestat] mean and std.dev: (408.00, 492.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3250)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 158, 214)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 408)
[M::mem_pestat] mean and std.dev: (170.59, 70.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 505)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (42, 176, 610)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1746)
[M::mem_pestat] mean and std.dev: (260.42, 351.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2314)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 288, 1847)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5191)
[M::mem_pestat] mean and std.dev: (745.84, 888.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6863)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 753552 reads in 199.177 CPU sec, 6.429 real sec
[M::mem_process_seqs] Processed 751852 reads in 134.969 CPU sec, 4.301 real sec
sorting block 55, #reads = 1116602 mem = 536882207 peak = 857812992
[M::process] read 750088 sequences (100000261 bp) in 2.656 CPU sec, 2.745 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 302669, 20, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 238, 940)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2442)
[M::mem_pestat] mean and std.dev: (551.39, 642.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3193)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 159, 216)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 414)
[M::mem_pestat] mean and std.dev: (171.73, 71.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 513)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (569, 798, 2718)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7016)
[M::mem_pestat] mean and std.dev: (1149.70, 1104.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9165)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 277, 1152)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3146)
[M::mem_pestat] mean and std.dev: (675.66, 726.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4143)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 56, #reads = 1115789 mem = 536882791 peak = 857812992
[M::process] read 749140 sequences (100000274 bp) in 3.165 CPU sec, 3.504 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 301923, 22, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (145, 247, 431)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1003)
[M::mem_pestat] mean and std.dev: (282.36, 204.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1289)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 159, 216)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 412)
[M::mem_pestat] mean and std.dev: (172.07, 71.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 510)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (246, 744, 1418)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3762)
[M::mem_pestat] mean and std.dev: (982.95, 893.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4934)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 541, 924)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2444)
[M::mem_pestat] mean and std.dev: (610.67, 591.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3204)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 750356 reads in 197.420 CPU sec, 6.358 real sec
[M::mem_process_seqs] Processed 750088 reads in 133.017 CPU sec, 4.243 real sec
[M::process] read 749370 sequences (100000143 bp) in 2.419 CPU sec, 2.519 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 301863, 19, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 311, 723)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1849)
[M::mem_pestat] mean and std.dev: (381.50, 315.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2412)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 160, 217)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 415)
[M::mem_pestat] mean and std.dev: (172.65, 71.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 514)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (139, 288, 551)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1375)
[M::mem_pestat] mean and std.dev: (300.50, 258.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1787)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 328, 1170)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3152)
[M::mem_pestat] mean and std.dev: (574.30, 495.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4143)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 57, #reads = 1114870 mem = 536879283 peak = 857812992
[M::process] read 748204 sequences (100000206 bp) in 2.913 CPU sec, 3.259 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 301499, 24, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 209, 999)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2695)
[M::mem_pestat] mean and std.dev: (591.81, 681.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3543)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 160, 217)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 415)
[M::mem_pestat] mean and std.dev: (172.71, 72.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 514)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (530, 904, 1308)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2864)
[M::mem_pestat] mean and std.dev: (697.75, 422.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3642)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 291, 626)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1542)
[M::mem_pestat] mean and std.dev: (346.47, 284.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2000)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 749140 reads in 194.188 CPU sec, 6.275 real sec
[M::mem_process_seqs] Processed 749370 reads in 132.600 CPU sec, 4.239 real sec
[M::process] read 748058 sequences (100000162 bp) in 2.754 CPU sec, 2.942 real sec...
sorting block 58, #reads = 1115479 mem = 536878008 peak = 857812992
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 301853, 23, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 266, 809)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2049)
[M::mem_pestat] mean and std.dev: (514.03, 465.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2669)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 161, 218)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 418)
[M::mem_pestat] mean and std.dev: (173.27, 72.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 518)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 471, 1073)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2905)
[M::mem_pestat] mean and std.dev: (654.65, 612.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3821)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 327, 692)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1718)
[M::mem_pestat] mean and std.dev: (425.72, 326.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2231)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 747876 sequences (100000160 bp) in 3.139 CPU sec, 3.506 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 301140, 28, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (227, 321, 626)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1424)
[M::mem_pestat] mean and std.dev: (323.20, 199.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1823)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 161, 218)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 418)
[M::mem_pestat] mean and std.dev: (173.67, 72.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 518)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 599, 1573)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4363)
[M::mem_pestat] mean and std.dev: (794.00, 775.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5758)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 199, 612)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1484)
[M::mem_pestat] mean and std.dev: (375.38, 352.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1920)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 748204 reads in 196.990 CPU sec, 6.339 real sec
[M::mem_process_seqs] Processed 748058 reads in 132.837 CPU sec, 4.224 real sec
sorting block 59, #reads = 1113220 mem = 536883863 peak = 857812992
[M::process] read 748618 sequences (100000237 bp) in 2.566 CPU sec, 2.671 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23, 301376, 35, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (247, 410, 762)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1792)
[M::mem_pestat] mean and std.dev: (406.25, 291.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2307)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (119, 161, 218)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 416)
[M::mem_pestat] mean and std.dev: (173.80, 72.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 515)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (86, 387, 984)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2780)
[M::mem_pestat] mean and std.dev: (625.38, 685.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3678)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 451, 1043)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2713)
[M::mem_pestat] mean and std.dev: (548.89, 432.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3548)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 60, #reads = 1113380 mem = 536881222 peak = 857812992
[M::process] read 748562 sequences (100000071 bp) in 3.002 CPU sec, 3.323 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 301495, 24, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 188, 1344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3738)
[M::mem_pestat] mean and std.dev: (412.33, 535.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4935)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 160, 218)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 418)
[M::mem_pestat] mean and std.dev: (173.39, 72.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 518)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (76, 221, 727)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2029)
[M::mem_pestat] mean and std.dev: (295.29, 353.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2680)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 300, 514)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1124)
[M::mem_pestat] mean and std.dev: (265.81, 142.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1429)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 747876 reads in 198.763 CPU sec, 6.389 real sec
[M::mem_process_seqs] Processed 748618 reads in 135.017 CPU sec, 4.295 real sec
[M::process] read 748448 sequences (100000032 bp) in 2.289 CPU sec, 2.380 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 301582, 26, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (277, 419, 884)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2098)
[M::mem_pestat] mean and std.dev: (513.84, 302.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2705)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 160, 218)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 418)
[M::mem_pestat] mean and std.dev: (173.28, 72.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 518)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (141, 389, 1599)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4515)
[M::mem_pestat] mean and std.dev: (711.92, 683.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5973)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 343, 921)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2443)
[M::mem_pestat] mean and std.dev: (462.26, 435.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3204)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 61, #reads = 1111961 mem = 536876082 peak = 857812992
[M::process] read 759642 sequences (100000118 bp) in 3.140 CPU sec, 3.592 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 301871, 19, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 304, 843)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2207)
[M::mem_pestat] mean and std.dev: (469.24, 441.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2889)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 161, 218)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 418)
[M::mem_pestat] mean and std.dev: (173.45, 72.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 518)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (450, 835, 2347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6141)
[M::mem_pestat] mean and std.dev: (1398.11, 1347.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8038)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 234, 623)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1545)
[M::mem_pestat] mean and std.dev: (338.31, 300.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2006)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 748562 reads in 197.000 CPU sec, 6.374 real sec
[M::mem_process_seqs] Processed 748448 reads in 136.295 CPU sec, 4.372 real sec
[M::process] read 762374 sequences (100000020 bp) in 2.810 CPU sec, 2.925 real sec...
sorting block 62, #reads = 1112706 mem = 536880572 peak = 857812992
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 304644, 33, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 479, 2472)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7028)
[M::mem_pestat] mean and std.dev: (1189.06, 1243.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9306)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (114, 153, 206)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 390)
[M::mem_pestat] mean and std.dev: (164.37, 66.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 482)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (225, 583, 1766)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4848)
[M::mem_pestat] mean and std.dev: (1007.25, 1089.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6389)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 373, 926)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2412)
[M::mem_pestat] mean and std.dev: (530.08, 455.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3155)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 760706 sequences (100000272 bp) in 2.824 CPU sec, 3.103 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 306393, 17, 24)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 381, 995)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2563)
[M::mem_pestat] mean and std.dev: (593.20, 587.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3347)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (113, 151, 202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 380)
[M::mem_pestat] mean and std.dev: (161.74, 64.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 469)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (281, 880, 2614)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7280)
[M::mem_pestat] mean and std.dev: (1251.24, 1150.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9613)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 334, 1128)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3052)
[M::mem_pestat] mean and std.dev: (651.78, 752.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4014)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 759642 reads in 212.576 CPU sec, 6.859 real sec
[M::process] read 758242 sequences (100000242 bp) in 2.256 CPU sec, 2.333 real sec...
sorting block 63, #reads = 1112326 mem = 536877822 peak = 857812992
[M::mem_process_seqs] Processed 762374 reads in 144.755 CPU sec, 4.651 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20, 305998, 25, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 420, 957)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2427)
[M::mem_pestat] mean and std.dev: (528.16, 490.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3162)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (113, 152, 204)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 386)
[M::mem_pestat] mean and std.dev: (163.35, 66.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 477)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (295, 729, 1875)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5035)
[M::mem_pestat] mean and std.dev: (1181.32, 1218.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6615)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 413, 2060)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5868)
[M::mem_pestat] mean and std.dev: (991.80, 1247.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7772)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 64, #reads = 1116946 mem = 536890288 peak = 857812992
[M::process] read 757266 sequences (100000010 bp) in 3.542 CPU sec, 3.838 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 305334, 33, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 325, 760)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1912)
[M::mem_pestat] mean and std.dev: (483.98, 437.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2488)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (114, 153, 206)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 390)
[M::mem_pestat] mean and std.dev: (164.96, 67.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 482)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 447, 1268)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3368)
[M::mem_pestat] mean and std.dev: (613.34, 640.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4418)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 440, 1344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3716)
[M::mem_pestat] mean and std.dev: (741.03, 760.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4902)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 760706 reads in 201.014 CPU sec, 6.454 real sec
[M::mem_process_seqs] Processed 758242 reads in 137.236 CPU sec, 4.373 real sec
[M::process] read 756554 sequences (100000048 bp) in 2.663 CPU sec, 2.814 real sec...
sorting block 65, #reads = 1119661 mem = 536879188 peak = 857812992
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 304758, 20, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 258, 798)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2096)
[M::mem_pestat] mean and std.dev: (408.68, 499.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2745)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (115, 154, 208)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 394)
[M::mem_pestat] mean and std.dev: (165.94, 67.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 487)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (371, 665, 3109)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8585)
[M::mem_pestat] mean and std.dev: (1428.60, 1546.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11323)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 366, 1027)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2685)
[M::mem_pestat] mean and std.dev: (523.34, 549.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3514)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 755834 sequences (100000208 bp) in 2.881 CPU sec, 3.193 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 303910, 21, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (123, 252, 389)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 921)
[M::mem_pestat] mean and std.dev: (244.50, 162.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1187)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (115, 155, 209)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 397)
[M::mem_pestat] mean and std.dev: (166.63, 68.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 491)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (111, 458, 2575)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7503)
[M::mem_pestat] mean and std.dev: (1116.10, 1426.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9967)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 391, 1579)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4337)
[M::mem_pestat] mean and std.dev: (845.71, 976.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5716)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 757266 reads in 200.752 CPU sec, 6.462 real sec
[M::mem_process_seqs] Processed 756554 reads in 138.977 CPU sec, 4.410 real sec
[M::process] read 754754 sequences (100000004 bp) in 2.551 CPU sec, 2.625 real sec...
sorting block 66, #reads = 1121383 mem = 536878024 peak = 857812992
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 304494, 32, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (135, 238, 856)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2298)
[M::mem_pestat] mean and std.dev: (375.69, 372.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3019)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (115, 155, 210)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 400)
[M::mem_pestat] mean and std.dev: (167.26, 68.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 495)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (84, 256, 966)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2730)
[M::mem_pestat] mean and std.dev: (446.18, 521.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3612)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 328, 448)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1050)
[M::mem_pestat] mean and std.dev: (312.15, 195.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1351)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 754556 sequences (100000124 bp) in 3.402 CPU sec, 3.777 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 303558, 19, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 224, 638)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1576)
[M::mem_pestat] mean and std.dev: (419.09, 392.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2045)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (116, 156, 211)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 401)
[M::mem_pestat] mean and std.dev: (168.00, 69.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 496)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (109, 237, 932)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2578)
[M::mem_pestat] mean and std.dev: (454.11, 450.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3401)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 356, 898)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2372)
[M::mem_pestat] mean and std.dev: (481.56, 481.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3109)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 755834 reads in 200.319 CPU sec, 6.452 real sec
sorting block 67, #reads = 1118470 mem = 536883765 peak = 857812992
[M::mem_process_seqs] Processed 754754 reads in 137.861 CPU sec, 4.415 real sec
[M::process] read 753538 sequences (100000214 bp) in 2.699 CPU sec, 2.955 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 303711, 25, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 223, 811)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2097)
[M::mem_pestat] mean and std.dev: (428.59, 425.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2740)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (116, 156, 212)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 404)
[M::mem_pestat] mean and std.dev: (168.53, 70.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 500)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (121, 548, 1336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3766)
[M::mem_pestat] mean and std.dev: (639.00, 694.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4981)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 351, 1030)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2674)
[M::mem_pestat] mean and std.dev: (664.72, 740.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3626)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 68, #reads = 1118906 mem = 536879123 peak = 866041856
[M::process] read 753144 sequences (100000095 bp) in 2.934 CPU sec, 3.341 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 302968, 25, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (135, 193, 414)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 972)
[M::mem_pestat] mean and std.dev: (257.38, 200.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1251)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (116, 157, 213)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 407)
[M::mem_pestat] mean and std.dev: (169.26, 70.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 504)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (269, 817, 2010)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5492)
[M::mem_pestat] mean and std.dev: (921.00, 980.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7233)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 455, 1182)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3128)
[M::mem_pestat] mean and std.dev: (717.05, 635.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4101)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 754556 reads in 200.142 CPU sec, 6.497 real sec
[M::mem_process_seqs] Processed 753538 reads in 136.580 CPU sec, 4.347 real sec
[M::process] read 752186 sequences (100000164 bp) in 2.571 CPU sec, 2.691 real sec...
sorting block 69, #reads = 1116673 mem = 536883964 peak = 866041856
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 302869, 13, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 245, 488)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1164)
[M::mem_pestat] mean and std.dev: (353.53, 296.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1541)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (116, 157, 214)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 410)
[M::mem_pestat] mean and std.dev: (169.95, 70.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 508)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (53, 944, 1638)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4808)
[M::mem_pestat] mean and std.dev: (888.92, 917.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6393)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 209, 553)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1297)
[M::mem_pestat] mean and std.dev: (300.27, 219.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1669)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 750884 sequences (100000039 bp) in 3.184 CPU sec, 3.507 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 303018, 31, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 349, 975)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2573)
[M::mem_pestat] mean and std.dev: (601.82, 558.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3372)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 158, 215)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 411)
[M::mem_pestat] mean and std.dev: (170.85, 71.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 509)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 381, 903)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2371)
[M::mem_pestat] mean and std.dev: (557.97, 525.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3105)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 261, 1043)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2745)
[M::mem_pestat] mean and std.dev: (545.04, 552.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3596)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 753144 reads in 205.944 CPU sec, 6.636 real sec
[M::mem_process_seqs] Processed 752186 reads in 141.053 CPU sec, 4.502 real sec
sorting block 70, #reads = 1116777 mem = 536886514 peak = 866041856
[M::process] read 750688 sequences (100000012 bp) in 2.890 CPU sec, 3.031 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 302405, 26, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 351, 879)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2269)
[M::mem_pestat] mean and std.dev: (450.97, 369.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2964)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 159, 215)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 411)
[M::mem_pestat] mean and std.dev: (171.19, 71.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 509)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 352, 415)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 885)
[M::mem_pestat] mean and std.dev: (298.23, 204.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1120)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 336, 1081)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2845)
[M::mem_pestat] mean and std.dev: (677.71, 671.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3727)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 750524 sequences (100000081 bp) in 2.864 CPU sec, 3.134 real sec...
sorting block 71, #reads = 1114687 mem = 536879480 peak = 866041856
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 302174, 17, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 290, 971)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2487)
[M::mem_pestat] mean and std.dev: (545.80, 522.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3245)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 158, 215)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 411)
[M::mem_pestat] mean and std.dev: (170.98, 70.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 509)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (79, 207, 3264)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9634)
[M::mem_pestat] mean and std.dev: (1503.82, 2308.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12819)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 317, 769)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1905)
[M::mem_pestat] mean and std.dev: (462.50, 454.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2473)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 750884 reads in 203.131 CPU sec, 6.555 real sec
[M::process] read 749486 sequences (100000213 bp) in 2.232 CPU sec, 2.304 real sec...
[M::mem_process_seqs] Processed 750688 reads in 138.801 CPU sec, 4.446 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 302308, 26, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (137, 263, 371)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 839)
[M::mem_pestat] mean and std.dev: (237.89, 134.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1073)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 159, 215)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 411)
[M::mem_pestat] mean and std.dev: (171.16, 71.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 509)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (136, 421, 3445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10063)
[M::mem_pestat] mean and std.dev: (1743.27, 2329.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13372)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 262, 576)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1350)
[M::mem_pestat] mean and std.dev: (322.43, 210.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1737)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 72, #reads = 1113318 mem = 536881018 peak = 866041856
[M::process] read 749994 sequences (100000160 bp) in 3.164 CPU sec, 3.514 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 301686, 26, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 354, 649)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1601)
[M::mem_pestat] mean and std.dev: (457.33, 377.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2077)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 159, 216)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 412)
[M::mem_pestat] mean and std.dev: (171.82, 71.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 510)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 492, 1170)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3084)
[M::mem_pestat] mean and std.dev: (599.32, 590.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4041)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (119, 202, 391)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 935)
[M::mem_pestat] mean and std.dev: (239.85, 168.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1207)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 750524 reads in 204.317 CPU sec, 6.588 real sec
[M::mem_process_seqs] Processed 749486 reads in 139.925 CPU sec, 4.485 real sec
[M::process] read 750008 sequences (100000199 bp) in 3.297 CPU sec, 3.502 real sec...
sorting block 73, #reads = 1112468 mem = 536886392 peak = 866041856
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 302194, 24, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 404, 696)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1700)
[M::mem_pestat] mean and std.dev: (438.72, 320.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2202)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 159, 215)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 409)
[M::mem_pestat] mean and std.dev: (171.47, 71.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 506)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 739, 1482)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4100)
[M::mem_pestat] mean and std.dev: (859.09, 946.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5409)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (235, 380, 980)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2470)
[M::mem_pestat] mean and std.dev: (574.65, 570.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3215)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 749578 sequences (100000050 bp) in 2.682 CPU sec, 3.041 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 301576, 15, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 194, 402)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 898)
[M::mem_pestat] mean and std.dev: (225.83, 123.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1146)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 159, 216)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 412)
[M::mem_pestat] mean and std.dev: (172.02, 71.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 510)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (127, 464, 1685)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4801)
[M::mem_pestat] mean and std.dev: (920.20, 1015.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6359)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 435, 1219)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3295)
[M::mem_pestat] mean and std.dev: (686.87, 696.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4333)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 749994 reads in 203.008 CPU sec, 6.614 real sec
[M::mem_process_seqs] Processed 750008 reads in 140.394 CPU sec, 4.548 real sec
sorting block 74, #reads = 1112095 mem = 536879538 peak = 866041856
[M::process] read 749122 sequences (100000125 bp) in 2.709 CPU sec, 2.991 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 301860, 15, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 587, 1528)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4170)
[M::mem_pestat] mean and std.dev: (700.41, 587.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5491)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 160, 217)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 415)
[M::mem_pestat] mean and std.dev: (172.30, 71.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 514)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (428, 675, 2667)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7145)
[M::mem_pestat] mean and std.dev: (1271.20, 1299.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9384)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (140, 228, 781)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2063)
[M::mem_pestat] mean and std.dev: (384.35, 415.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2704)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 75, #reads = 1112977 mem = 536880715 peak = 866041856
[M::process] read 749720 sequences (100000156 bp) in 3.120 CPU sec, 3.497 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 301810, 15, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 264, 1690)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4740)
[M::mem_pestat] mean and std.dev: (810.92, 1000.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6265)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 160, 217)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 415)
[M::mem_pestat] mean and std.dev: (172.60, 71.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 514)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (276, 629, 1367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3549)
[M::mem_pestat] mean and std.dev: (637.15, 514.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4640)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 320, 746)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1866)
[M::mem_pestat] mean and std.dev: (416.55, 329.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2426)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 749578 reads in 201.591 CPU sec, 6.529 real sec
[M::mem_process_seqs] Processed 749122 reads in 137.212 CPU sec, 4.499 real sec
[M::process] read 749202 sequences (100000143 bp) in 2.483 CPU sec, 2.739 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 301869, 17, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 336, 1055)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2845)
[M::mem_pestat] mean and std.dev: (573.55, 579.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3740)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 159, 216)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 412)
[M::mem_pestat] mean and std.dev: (171.94, 71.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 510)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (264, 478, 984)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2424)
[M::mem_pestat] mean and std.dev: (554.00, 523.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3144)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 273, 1618)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4514)
[M::mem_pestat] mean and std.dev: (812.91, 963.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5962)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 76, #reads = 1112440 mem = 536878281 peak = 866041856
[M::process] read 749592 sequences (100000161 bp) in 2.849 CPU sec, 3.205 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 301777, 34, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 220, 755)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1949)
[M::mem_pestat] mean and std.dev: (423.85, 382.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2546)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 160, 217)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 415)
[M::mem_pestat] mean and std.dev: (172.35, 71.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 514)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (123, 491, 1068)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2958)
[M::mem_pestat] mean and std.dev: (569.53, 658.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3903)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 680, 1283)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3453)
[M::mem_pestat] mean and std.dev: (769.21, 809.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4538)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 749720 reads in 206.755 CPU sec, 6.711 real sec
[M::mem_process_seqs] Processed 749202 reads in 140.606 CPU sec, 4.511 real sec
[M::process] read 763774 sequences (100000164 bp) in 2.859 CPU sec, 3.054 real sec...
sorting block 77, #reads = 1112470 mem = 536879961 peak = 866041856
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 301969, 30, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 250, 839)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2199)
[M::mem_pestat] mean and std.dev: (391.69, 420.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2879)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 159, 217)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 415)
[M::mem_pestat] mean and std.dev: (172.34, 72.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 514)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 740, 2128)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6002)
[M::mem_pestat] mean and std.dev: (1154.28, 1311.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7939)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 297, 535)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1211)
[M::mem_pestat] mean and std.dev: (359.86, 276.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1549)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 764700 sequences (100000048 bp) in 2.976 CPU sec, 3.427 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 306500, 24, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 223, 881)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2295)
[M::mem_pestat] mean and std.dev: (403.88, 430.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3002)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (112, 150, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 379)
[M::mem_pestat] mean and std.dev: (161.26, 64.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 468)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (96, 278, 1021)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2871)
[M::mem_pestat] mean and std.dev: (675.58, 842.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4045)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 206, 462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1068)
[M::mem_pestat] mean and std.dev: (276.45, 192.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1371)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 749592 reads in 212.128 CPU sec, 6.822 real sec
[M::process] read 764116 sequences (100000054 bp) in 2.366 CPU sec, 2.437 real sec...
sorting block 78, #reads = 1111979 mem = 536879471 peak = 866041856
[M::mem_process_seqs] Processed 763774 reads in 147.215 CPU sec, 4.696 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 306809, 16, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 219, 1502)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4206)
[M::mem_pestat] mean and std.dev: (722.43, 923.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5558)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (112, 149, 200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 376)
[M::mem_pestat] mean and std.dev: (160.36, 63.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 464)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 522, 2728)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7746)
[M::mem_pestat] mean and std.dev: (979.79, 1434.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10255)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 262, 469)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1077)
[M::mem_pestat] mean and std.dev: (285.67, 164.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1381)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 79, #reads = 1114161 mem = 536884354 peak = 866041856
[M::process] read 762370 sequences (100000080 bp) in 3.570 CPU sec, 3.919 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 306784, 22, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 245, 836)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2172)
[M::mem_pestat] mean and std.dev: (429.16, 446.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2840)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (112, 150, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 379)
[M::mem_pestat] mean and std.dev: (160.92, 64.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 468)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 1050, 2694)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7696)
[M::mem_pestat] mean and std.dev: (1307.57, 1291.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10197)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 218, 1092)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3004)
[M::mem_pestat] mean and std.dev: (541.72, 637.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3960)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 764700 reads in 219.943 CPU sec, 7.117 real sec
[M::mem_process_seqs] Processed 764116 reads in 151.198 CPU sec, 4.852 real sec
[M::process] read 760958 sequences (100000032 bp) in 2.503 CPU sec, 2.610 real sec...
sorting block 80, #reads = 1118570 mem = 536879017 peak = 866041856
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 306211, 22, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 266, 447)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1033)
[M::mem_pestat] mean and std.dev: (269.11, 165.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1326)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (113, 151, 203)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 383)
[M::mem_pestat] mean and std.dev: (162.21, 65.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 473)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 408, 1909)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5331)
[M::mem_pestat] mean and std.dev: (898.85, 1062.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7042)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 453, 1065)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2845)
[M::mem_pestat] mean and std.dev: (584.48, 539.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3735)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 759828 sequences (100000246 bp) in 3.312 CPU sec, 3.711 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 305429, 11, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (128, 217, 801)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2147)
[M::mem_pestat] mean and std.dev: (432.28, 430.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2820)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (113, 152, 204)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 386)
[M::mem_pestat] mean and std.dev: (163.34, 66.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 477)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 634, 1371)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3671)
[M::mem_pestat] mean and std.dev: (485.22, 414.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4821)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 361, 684)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1694)
[M::mem_pestat] mean and std.dev: (421.06, 350.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2199)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 762370 reads in 215.957 CPU sec, 6.950 real sec
[M::process] read 759214 sequences (100000268 bp) in 2.151 CPU sec, 2.184 real sec...
[M::mem_process_seqs] Processed 760958 reads in 145.790 CPU sec, 4.660 real sec
sorting block 81, #reads = 1114331 mem = 536879080 peak = 866041856
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 305953, 24, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 171, 258)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 468)
[M::mem_pestat] mean and std.dev: (186.36, 75.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 573)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (114, 152, 205)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 387)
[M::mem_pestat] mean and std.dev: (163.93, 66.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 478)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (143, 541, 2353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6773)
[M::mem_pestat] mean and std.dev: (1187.12, 1324.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8983)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 337, 674)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1670)
[M::mem_pestat] mean and std.dev: (413.40, 296.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2168)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 758364 sequences (100000141 bp) in 3.090 CPU sec, 3.815 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 305218, 15, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (145, 193, 643)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1639)
[M::mem_pestat] mean and std.dev: (330.61, 321.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2137)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (114, 153, 205)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 387)
[M::mem_pestat] mean and std.dev: (164.17, 66.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 478)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (267, 324, 609)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1293)
[M::mem_pestat] mean and std.dev: (411.00, 218.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1635)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (142, 291, 758)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1990)
[M::mem_pestat] mean and std.dev: (426.93, 422.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2606)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 759828 reads in 212.441 CPU sec, 6.909 real sec
sorting block 82, #reads = 1117616 mem = 536878344 peak = 866041856
[M::mem_process_seqs] Processed 759214 reads in 144.304 CPU sec, 4.619 real sec
[M::process] read 757908 sequences (100000205 bp) in 2.808 CPU sec, 2.955 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 304972, 21, 23)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 284, 1784)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5056)
[M::mem_pestat] mean and std.dev: (594.18, 734.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6692)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (114, 153, 207)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 393)
[M::mem_pestat] mean and std.dev: (165.41, 67.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 486)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (140, 263, 3445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10055)
[M::mem_pestat] mean and std.dev: (1502.48, 2462.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13360)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 411, 4015)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 11669)
[M::mem_pestat] mean and std.dev: (2268.91, 2896.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 15496)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 83, #reads = 1115326 mem = 536881521 peak = 873906176
[M::process] read 757834 sequences (100000171 bp) in 2.924 CPU sec, 3.323 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 304992, 19, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (116, 214, 651)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1721)
[M::mem_pestat] mean and std.dev: (294.96, 267.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2256)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (114, 153, 207)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 393)
[M::mem_pestat] mean and std.dev: (165.54, 67.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 486)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 320, 1192)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3170)
[M::mem_pestat] mean and std.dev: (758.63, 849.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4159)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 232, 562)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1344)
[M::mem_pestat] mean and std.dev: (324.90, 287.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1735)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 758364 reads in 204.806 CPU sec, 6.676 real sec
[M::mem_process_seqs] Processed 757908 reads in 140.163 CPU sec, 4.537 real sec
[M::process] read 756526 sequences (100000004 bp) in 2.546 CPU sec, 2.936 real sec...
sorting block 84, #reads = 1116159 mem = 536884481 peak = 873906176
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 304927, 23, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (130, 335, 569)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1447)
[M::mem_pestat] mean and std.dev: (401.96, 353.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1886)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (114, 154, 208)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 396)
[M::mem_pestat] mean and std.dev: (166.09, 68.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 490)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 429, 1102)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2960)
[M::mem_pestat] mean and std.dev: (669.32, 752.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3889)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 271, 641)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1559)
[M::mem_pestat] mean and std.dev: (317.35, 230.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2018)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 756218 sequences (100000192 bp) in 2.880 CPU sec, 3.257 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 304356, 20, 19)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (139, 199, 457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1093)
[M::mem_pestat] mean and std.dev: (227.81, 151.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1411)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (115, 155, 210)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 400)
[M::mem_pestat] mean and std.dev: (167.38, 69.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 495)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (402, 740, 1769)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4503)
[M::mem_pestat] mean and std.dev: (1136.68, 1191.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5901)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 246, 1312)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3624)
[M::mem_pestat] mean and std.dev: (765.89, 902.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4780)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 757834 reads in 200.974 CPU sec, 6.489 real sec
[M::mem_process_seqs] Processed 756526 reads in 138.562 CPU sec, 4.432 real sec
sorting block 85, #reads = 1117760 mem = 536878999 peak = 873906176
[M::process] read 753722 sequences (100000130 bp) in 2.725 CPU sec, 2.894 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 304062, 25, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 397, 1380)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3786)
[M::mem_pestat] mean and std.dev: (670.73, 773.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4989)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (115, 155, 210)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 400)
[M::mem_pestat] mean and std.dev: (167.56, 69.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 495)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (294, 599, 2581)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7155)
[M::mem_pestat] mean and std.dev: (1357.44, 1447.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9442)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 323, 999)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2605)
[M::mem_pestat] mean and std.dev: (494.93, 416.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3408)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 752328 sequences (100000066 bp) in 3.128 CPU sec, 3.469 real sec...
sorting block 86, #reads = 1116145 mem = 536878886 peak = 873906176
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 303430, 25, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 202, 459)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1067)
[M::mem_pestat] mean and std.dev: (252.52, 157.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1371)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (116, 157, 213)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 407)
[M::mem_pestat] mean and std.dev: (169.54, 70.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 504)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 585, 2835)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8179)
[M::mem_pestat] mean and std.dev: (1602.44, 2100.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10851)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 331, 848)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2208)
[M::mem_pestat] mean and std.dev: (392.79, 327.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2888)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 756218 reads in 204.395 CPU sec, 6.631 real sec
[M::mem_process_seqs] Processed 753722 reads in 137.631 CPU sec, 4.435 real sec
[M::process] read 751974 sequences (100000182 bp) in 2.836 CPU sec, 2.975 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 302445, 19, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 301, 993)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2663)
[M::mem_pestat] mean and std.dev: (535.94, 628.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3498)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 158, 214)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 408)
[M::mem_pestat] mean and std.dev: (170.22, 70.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 505)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (385, 716, 2066)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5428)
[M::mem_pestat] mean and std.dev: (882.53, 796.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7109)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 385, 1145)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3105)
[M::mem_pestat] mean and std.dev: (596.29, 577.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4085)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 87, #reads = 1115062 mem = 536879497 peak = 873906176
[M::process] read 751328 sequences (100000224 bp) in 2.939 CPU sec, 3.353 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 302586, 22, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 371, 1114)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3042)
[M::mem_pestat] mean and std.dev: (663.49, 632.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4006)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 158, 214)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 408)
[M::mem_pestat] mean and std.dev: (170.45, 70.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 505)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (141, 327, 724)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1890)
[M::mem_pestat] mean and std.dev: (417.00, 381.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2473)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 279, 581)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1423)
[M::mem_pestat] mean and std.dev: (391.17, 327.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1844)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 752328 reads in 207.276 CPU sec, 6.703 real sec
[M::mem_process_seqs] Processed 751974 reads in 140.326 CPU sec, 4.481 real sec
[M::process] read 750758 sequences (100000030 bp) in 2.369 CPU sec, 2.505 real sec...
sorting block 88, #reads = 1114159 mem = 536879259 peak = 873906176
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 301846, 21, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (251, 372, 1767)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4799)
[M::mem_pestat] mean and std.dev: (786.37, 717.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6315)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 158, 214)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 408)
[M::mem_pestat] mean and std.dev: (170.60, 70.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 505)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (304, 493, 1800)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4792)
[M::mem_pestat] mean and std.dev: (961.10, 991.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6288)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 298, 1293)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3493)
[M::mem_pestat] mean and std.dev: (893.98, 1057.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5122)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 751118 sequences (100000275 bp) in 3.227 CPU sec, 3.743 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 302235, 30, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (138, 254, 917)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2475)
[M::mem_pestat] mean and std.dev: (473.12, 521.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3254)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 159, 215)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 411)
[M::mem_pestat] mean and std.dev: (170.93, 70.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 509)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (140, 231, 685)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1775)
[M::mem_pestat] mean and std.dev: (222.26, 189.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2320)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 296, 985)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2595)
[M::mem_pestat] mean and std.dev: (544.52, 547.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3400)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 751328 reads in 201.091 CPU sec, 6.535 real sec
[M::mem_process_seqs] Processed 750758 reads in 136.448 CPU sec, 4.358 real sec
sorting block 89, #reads = 1112229 mem = 536877503 peak = 873906176
[M::process] read 750720 sequences (100000216 bp) in 2.524 CPU sec, 2.661 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 302173, 21, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (135, 249, 814)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2172)
[M::mem_pestat] mean and std.dev: (522.10, 529.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2851)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 158, 215)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 411)
[M::mem_pestat] mean and std.dev: (171.12, 71.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 509)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 304, 1230)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3326)
[M::mem_pestat] mean and std.dev: (514.21, 529.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4374)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 308, 1594)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4466)
[M::mem_pestat] mean and std.dev: (555.70, 832.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5902)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 90, #reads = 1112468 mem = 536880871 peak = 873906176
[M::process] read 749626 sequences (100000186 bp) in 3.606 CPU sec, 4.173 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 302379, 23, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 518, 1468)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4110)
[M::mem_pestat] mean and std.dev: (824.69, 928.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5431)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 159, 215)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 411)
[M::mem_pestat] mean and std.dev: (171.28, 71.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 509)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (312, 702, 1405)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3591)
[M::mem_pestat] mean and std.dev: (757.85, 729.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4684)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 662, 1614)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4540)
[M::mem_pestat] mean and std.dev: (785.63, 746.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6003)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 751118 reads in 202.955 CPU sec, 6.540 real sec
[M::process] read 749156 sequences (100000015 bp) in 2.554 CPU sec, 2.706 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 301526, 16, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 326, 1115)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2963)
[M::mem_pestat] mean and std.dev: (591.26, 632.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3887)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 160, 216)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 412)
[M::mem_pestat] mean and std.dev: (172.04, 71.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 510)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (72, 396, 549)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1503)
[M::mem_pestat] mean and std.dev: (362.93, 363.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1980)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 284, 684)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1654)
[M::mem_pestat] mean and std.dev: (468.56, 413.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2139)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 749626 reads in 110.786 CPU sec, 3.491 real sec
[M::process] read 749788 sequences (100000229 bp) in 2.171 CPU sec, 2.195 real sec...
sorting block 91, #reads = 1113363 mem = 536879042 peak = 873906176
[M::mem_process_seqs] Processed 750720 reads in 306.593 CPU sec, 9.754 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 301787, 15, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 264, 781)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2049)
[M::mem_pestat] mean and std.dev: (378.30, 295.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2683)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 160, 216)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 412)
[M::mem_pestat] mean and std.dev: (172.35, 71.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 510)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (272, 802, 3015)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8501)
[M::mem_pestat] mean and std.dev: (1670.53, 1769.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11244)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 280, 658)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1624)
[M::mem_pestat] mean and std.dev: (382.33, 344.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2107)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 92, #reads = 1112825 mem = 536877235 peak = 873906176
[M::process] read 755678 sequences (100000130 bp) in 3.189 CPU sec, 3.357 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 301609, 20, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (227, 498, 3008)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8570)
[M::mem_pestat] mean and std.dev: (1600.29, 2122.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11351)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 159, 216)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 412)
[M::mem_pestat] mean and std.dev: (171.63, 71.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 510)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 360, 1386)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3830)
[M::mem_pestat] mean and std.dev: (577.05, 583.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5052)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 366, 1313)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3533)
[M::mem_pestat] mean and std.dev: (809.31, 944.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4643)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 749156 reads in 221.560 CPU sec, 7.124 real sec
[M::mem_process_seqs] Processed 749788 reads in 134.716 CPU sec, 4.338 real sec
[M::process] read 764332 sequences (100000070 bp) in 2.277 CPU sec, 2.364 real sec...
sorting block 93, #reads = 1112472 mem = 536880348 peak = 873906176
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 303538, 14, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (125, 208, 776)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2078)
[M::mem_pestat] mean and std.dev: (396.32, 432.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2729)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (115, 155, 210)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 400)
[M::mem_pestat] mean and std.dev: (167.12, 68.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 495)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 566, 959)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2553)
[M::mem_pestat] mean and std.dev: (732.29, 739.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3690)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 293, 899)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2355)
[M::mem_pestat] mean and std.dev: (448.34, 417.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3083)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 762824 sequences (100000229 bp) in 3.519 CPU sec, 3.791 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 307433, 15, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (132, 266, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 816)
[M::mem_pestat] mean and std.dev: (211.50, 106.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1044)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (112, 150, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 379)
[M::mem_pestat] mean and std.dev: (161.04, 64.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 468)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (391, 590, 679)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1255)
[M::mem_pestat] mean and std.dev: (385.92, 244.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1543)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 214, 1690)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4748)
[M::mem_pestat] mean and std.dev: (669.04, 914.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6277)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 755678 reads in 218.329 CPU sec, 6.977 real sec
[M::process] read 761176 sequences (100000197 bp) in 2.076 CPU sec, 2.084 real sec...
[M::mem_process_seqs] Processed 764332 reads in 140.190 CPU sec, 4.450 real sec
sorting block 94, #reads = 1109200 mem = 536884154 peak = 873906176
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 306736, 18, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (226, 602, 940)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2368)
[M::mem_pestat] mean and std.dev: (634.09, 446.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3082)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (113, 151, 203)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 383)
[M::mem_pestat] mean and std.dev: (162.23, 65.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 473)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (10, 289, 779)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2317)
[M::mem_pestat] mean and std.dev: (383.41, 497.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3086)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 298, 701)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1719)
[M::mem_pestat] mean and std.dev: (409.76, 328.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2228)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 760080 sequences (100000141 bp) in 4.249 CPU sec, 4.588 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 305838, 25, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (134, 178, 633)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1631)
[M::mem_pestat] mean and std.dev: (353.19, 369.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2130)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (113, 152, 204)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 386)
[M::mem_pestat] mean and std.dev: (163.29, 66.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 477)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (243, 363, 1588)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4278)
[M::mem_pestat] mean and std.dev: (917.64, 1038.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5623)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (242, 376, 1150)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2966)
[M::mem_pestat] mean and std.dev: (672.87, 626.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3874)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 762824 reads in 201.508 CPU sec, 6.472 real sec
sorting block 95, #reads = 1120088 mem = 536882602 peak = 873906176
[M::mem_process_seqs] Processed 761176 reads in 134.462 CPU sec, 4.281 real sec
[M::process] read 758494 sequences (100000157 bp) in 2.902 CPU sec, 3.128 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 306148, 19, 24)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 358, 956)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2492)
[M::mem_pestat] mean and std.dev: (626.10, 572.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3260)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (114, 152, 206)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 390)
[M::mem_pestat] mean and std.dev: (164.39, 67.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 482)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 394, 645)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1519)
[M::mem_pestat] mean and std.dev: (419.94, 319.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1956)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 179, 1214)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3350)
[M::mem_pestat] mean and std.dev: (507.09, 643.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4418)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 96, #reads = 1122551 mem = 536879210 peak = 873906176
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 305347, 28, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 259, 1656)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4646)
[M::mem_pestat] mean and std.dev: (772.41, 1029.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6141)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (114, 154, 207)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 393)
[M::mem_pestat] mean and std.dev: (165.53, 67.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 486)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 904, 1127)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2955)
[M::mem_pestat] mean and std.dev: (729.25, 643.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3869)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 206, 851)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2225)
[M::mem_pestat] mean and std.dev: (343.74, 294.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2912)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 757540 sequences (100000024 bp) in 3.468 CPU sec, 3.789 real sec...
[M::mem_process_seqs] Processed 760080 reads in 197.825 CPU sec, 6.377 real sec
[M::mem_process_seqs] Processed 758494 reads in 133.181 CPU sec, 4.261 real sec
[M::process] read 757006 sequences (100000043 bp) in 3.121 CPU sec, 3.355 real sec...
sorting block 97, #reads = 1121700 mem = 536877071 peak = 873906176
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 304483, 19, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (136, 172, 423)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 997)
[M::mem_pestat] mean and std.dev: (258.41, 206.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1284)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (115, 154, 208)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 394)
[M::mem_pestat] mean and std.dev: (166.15, 68.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 487)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 510, 865)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2229)
[M::mem_pestat] mean and std.dev: (552.72, 552.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2911)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 269, 1210)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3232)
[M::mem_pestat] mean and std.dev: (571.23, 594.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4243)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 756582 sequences (100000127 bp) in 2.890 CPU sec, 3.172 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 304750, 26, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 563, 1725)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4793)
[M::mem_pestat] mean and std.dev: (914.68, 973.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6327)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (115, 154, 209)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 397)
[M::mem_pestat] mean and std.dev: (166.71, 68.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 491)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (119, 802, 1036)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2870)
[M::mem_pestat] mean and std.dev: (561.73, 549.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3787)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 313, 821)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2089)
[M::mem_pestat] mean and std.dev: (612.45, 573.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2905)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 757540 reads in 201.138 CPU sec, 6.461 real sec
[M::mem_process_seqs] Processed 757006 reads in 138.384 CPU sec, 4.389 real sec
sorting block 98, #reads = 1120466 mem = 536877791 peak = 873906176
[M::process] read 757382 sequences (100000186 bp) in 2.414 CPU sec, 2.552 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (22, 304359, 21, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 624, 1309)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3593)
[M::mem_pestat] mean and std.dev: (657.42, 540.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4735)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (115, 155, 210)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 400)
[M::mem_pestat] mean and std.dev: (167.33, 69.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 495)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 491, 1403)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3789)
[M::mem_pestat] mean and std.dev: (691.38, 649.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4982)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 247, 647)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1627)
[M::mem_pestat] mean and std.dev: (322.39, 288.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2117)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 99, #reads = 1119826 mem = 536877441 peak = 873906176
[M::process] read 756656 sequences (100000081 bp) in 3.207 CPU sec, 3.416 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 304499, 30, 23)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (133, 197, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 748)
[M::mem_pestat] mean and std.dev: (179.81, 80.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 953)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (115, 154, 209)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 397)
[M::mem_pestat] mean and std.dev: (166.63, 68.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 491)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (105, 696, 1513)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4329)
[M::mem_pestat] mean and std.dev: (836.66, 914.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5737)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 204, 318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 628)
[M::mem_pestat] mean and std.dev: (208.68, 90.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 783)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 756582 reads in 204.311 CPU sec, 6.514 real sec
[M::process] read 755154 sequences (100000183 bp) in 2.321 CPU sec, 2.365 real sec...
[M::mem_process_seqs] Processed 757382 reads in 130.698 CPU sec, 4.135 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 304077, 16, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (127, 239, 969)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2653)
[M::mem_pestat] mean and std.dev: (422.68, 451.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3495)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (115, 155, 210)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 400)
[M::mem_pestat] mean and std.dev: (167.41, 69.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 495)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (251, 728, 1651)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4451)
[M::mem_pestat] mean and std.dev: (828.00, 803.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5851)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 371, 1144)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3018)
[M::mem_pestat] mean and std.dev: (534.78, 555.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3955)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 100, #reads = 1116154 mem = 536879468 peak = 873906176
[M::process] read 755240 sequences (100000143 bp) in 2.856 CPU sec, 3.026 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 304002, 25, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 340, 1408)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3894)
[M::mem_pestat] mean and std.dev: (688.60, 652.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5137)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (115, 156, 211)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 403)
[M::mem_pestat] mean and std.dev: (168.32, 69.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 499)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (142, 552, 1739)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4933)
[M::mem_pestat] mean and std.dev: (966.80, 1104.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6530)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 304, 2882)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8254)
[M::mem_pestat] mean and std.dev: (1055.75, 1368.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10940)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 756656 reads in 188.539 CPU sec, 6.036 real sec
[M::mem_process_seqs] Processed 755154 reads in 129.487 CPU sec, 4.092 real sec
[M::process] read 755016 sequences (100000116 bp) in 2.489 CPU sec, 2.558 real sec...
sorting block 101, #reads = 1119023 mem = 536884392 peak = 873906176
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 304062, 29, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (137, 226, 1221)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3389)
[M::mem_pestat] mean and std.dev: (664.53, 820.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4473)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (115, 155, 211)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 403)
[M::mem_pestat] mean and std.dev: (168.17, 69.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 499)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (133, 470, 1464)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4126)
[M::mem_pestat] mean and std.dev: (791.69, 796.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5457)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 336, 860)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2194)
[M::mem_pestat] mean and std.dev: (470.30, 405.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2861)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 753662 sequences (100000046 bp) in 3.322 CPU sec, 3.587 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 303890, 21, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 238, 664)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1694)
[M::mem_pestat] mean and std.dev: (298.84, 232.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2209)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (116, 156, 211)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 401)
[M::mem_pestat] mean and std.dev: (168.05, 69.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 496)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (118, 391, 974)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2686)
[M::mem_pestat] mean and std.dev: (597.71, 628.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3542)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 371, 1927)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5389)
[M::mem_pestat] mean and std.dev: (880.93, 970.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7120)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 755240 reads in 189.832 CPU sec, 6.075 real sec
[M::mem_process_seqs] Processed 755016 reads in 129.069 CPU sec, 4.085 real sec
sorting block 102, #reads = 1119088 mem = 536890726 peak = 873906176
[M::process] read 752958 sequences (100000168 bp) in 2.634 CPU sec, 2.735 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 303596, 23, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 229, 1064)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2858)
[M::mem_pestat] mean and std.dev: (539.08, 626.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3755)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (116, 157, 214)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 410)
[M::mem_pestat] mean and std.dev: (170.01, 71.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 508)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 767, 2794)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7942)
[M::mem_pestat] mean and std.dev: (1194.64, 1329.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10516)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 340, 1476)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4084)
[M::mem_pestat] mean and std.dev: (766.90, 892.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5388)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 103, #reads = 1117851 mem = 536880630 peak = 873906176
[M::process] read 751968 sequences (100000012 bp) in 2.997 CPU sec, 3.212 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 303155, 28, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 252, 857)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2267)
[M::mem_pestat] mean and std.dev: (386.92, 309.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2972)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (116, 157, 214)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 410)
[M::mem_pestat] mean and std.dev: (170.18, 71.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 508)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (60, 232, 543)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1509)
[M::mem_pestat] mean and std.dev: (315.54, 338.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1992)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (242, 394, 1305)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3431)
[M::mem_pestat] mean and std.dev: (573.96, 571.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4494)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 753662 reads in 197.106 CPU sec, 6.287 real sec
[M::mem_process_seqs] Processed 752958 reads in 132.789 CPU sec, 4.190 real sec
[M::process] read 751840 sequences (100000205 bp) in 2.385 CPU sec, 2.440 real sec...
sorting block 104, #reads = 1116562 mem = 536889605 peak = 873906176
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23, 302734, 21, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (128, 159, 313)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 683)
[M::mem_pestat] mean and std.dev: (220.33, 152.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 868)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 158, 214)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 408)
[M::mem_pestat] mean and std.dev: (170.35, 70.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 505)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (363, 493, 1402)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3480)
[M::mem_pestat] mean and std.dev: (739.60, 727.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4519)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 336, 1330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3662)
[M::mem_pestat] mean and std.dev: (728.42, 821.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4828)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 751166 sequences (100000047 bp) in 3.225 CPU sec, 3.358 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 302143, 18, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 395, 617)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1505)
[M::mem_pestat] mean and std.dev: (385.37, 266.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1949)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 158, 214)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 408)
[M::mem_pestat] mean and std.dev: (170.39, 70.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 505)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (139, 899, 1307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3643)
[M::mem_pestat] mean and std.dev: (954.72, 761.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4811)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 247, 801)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2049)
[M::mem_pestat] mean and std.dev: (484.64, 485.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2673)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 750750 sequences (100000254 bp) in 1.906 CPU sec, 1.923 real sec...
[M::mem_process_seqs] Processed 751968 reads in 196.709 CPU sec, 6.277 real sec
[M::mem_process_seqs] Processed 751840 reads in 132.348 CPU sec, 4.211 real sec
sorting block 105, #reads = 1114377 mem = 536885405 peak = 873906176
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 302209, 30, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 518, 1021)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2713)
[M::mem_pestat] mean and std.dev: (669.92, 613.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3559)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 158, 215)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 411)
[M::mem_pestat] mean and std.dev: (171.00, 71.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 509)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (72, 280, 1573)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4575)
[M::mem_pestat] mean and std.dev: (951.13, 1218.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6076)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 529, 996)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2562)
[M::mem_pestat] mean and std.dev: (546.62, 443.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3345)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 750854 sequences (100000256 bp) in 3.141 CPU sec, 3.311 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 302492, 25, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (129, 186, 551)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1395)
[M::mem_pestat] mean and std.dev: (261.48, 259.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1817)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 159, 215)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 411)
[M::mem_pestat] mean and std.dev: (171.16, 71.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 509)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (403, 681, 2713)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7333)
[M::mem_pestat] mean and std.dev: (1638.04, 1867.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9643)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 322, 1587)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4367)
[M::mem_pestat] mean and std.dev: (878.82, 1114.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5757)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 751166 reads in 199.791 CPU sec, 6.383 real sec
[M::process] read 750536 sequences (100000090 bp) in 2.204 CPU sec, 2.227 real sec...
sorting block 106, #reads = 1113660 mem = 536887030 peak = 873906176
[M::mem_process_seqs] Processed 750750 reads in 133.729 CPU sec, 4.236 real sec
sorting block 107, #reads = 1112037 mem = 536879168 peak = 873906176
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 302395, 21, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (145, 664, 1431)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4003)
[M::mem_pestat] mean and std.dev: (725.20, 753.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5289)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 158, 215)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 411)
[M::mem_pestat] mean and std.dev: (170.99, 71.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 509)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (74, 501, 1701)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4955)
[M::mem_pestat] mean and std.dev: (799.10, 899.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6582)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 379, 1602)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4430)
[M::mem_pestat] mean and std.dev: (801.89, 971.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5844)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 750346 sequences (100000196 bp) in 2.929 CPU sec, 3.049 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 301861, 22, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (125, 187, 737)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1961)
[M::mem_pestat] mean and std.dev: (528.54, 618.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3004)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 159, 215)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 409)
[M::mem_pestat] mean and std.dev: (171.18, 71.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 506)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (252, 804, 1440)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3816)
[M::mem_pestat] mean and std.dev: (1019.33, 994.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5004)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 239, 871)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2267)
[M::mem_pestat] mean and std.dev: (470.07, 404.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2965)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 751852 sequences (100000198 bp) in 2.208 CPU sec, 2.212 real sec...
[M::mem_process_seqs] Processed 750854 reads in 208.596 CPU sec, 6.871 real sec
[M::mem_process_seqs] Processed 750536 reads in 140.421 CPU sec, 4.465 real sec
sorting block 108, #reads = 1111992 mem = 536878084 peak = 873906176
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 301713, 19, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 243, 867)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2307)
[M::mem_pestat] mean and std.dev: (417.95, 450.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3027)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 159, 215)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 411)
[M::mem_pestat] mean and std.dev: (171.47, 71.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 509)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (107, 896, 2000)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5786)
[M::mem_pestat] mean and std.dev: (1130.16, 1188.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7679)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 234, 607)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1547)
[M::mem_pestat] mean and std.dev: (342.62, 290.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2017)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 768536 sequences (100000284 bp) in 3.239 CPU sec, 3.467 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 301689, 29, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 252, 561)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1349)
[M::mem_pestat] mean and std.dev: (333.00, 284.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1743)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 158, 214)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 408)
[M::mem_pestat] mean and std.dev: (170.22, 70.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 505)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (243, 449, 1693)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4593)
[M::mem_pestat] mean and std.dev: (507.50, 498.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6043)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 446, 1117)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3009)
[M::mem_pestat] mean and std.dev: (699.42, 749.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3955)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 766252 sequences (100000064 bp) in 2.268 CPU sec, 2.271 real sec...
[M::mem_process_seqs] Processed 750346 reads in 225.192 CPU sec, 7.190 real sec
sorting block 109, #reads = 1109619 mem = 536878613 peak = 873906176
[M::mem_process_seqs] Processed 751852 reads in 160.637 CPU sec, 5.108 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 307887, 19, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 641, 1363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3795)
[M::mem_pestat] mean and std.dev: (953.86, 996.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5011)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 147, 196)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 366)
[M::mem_pestat] mean and std.dev: (157.60, 61.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 451)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 243, 1589)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4471)
[M::mem_pestat] mean and std.dev: (793.33, 1063.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5912)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 280, 1059)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2843)
[M::mem_pestat] mean and std.dev: (485.38, 547.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3735)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 764904 sequences (100000028 bp) in 3.808 CPU sec, 4.027 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 307294, 19, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (128, 197, 460)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1124)
[M::mem_pestat] mean and std.dev: (236.12, 151.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1456)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (112, 148, 199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 373)
[M::mem_pestat] mean and std.dev: (159.47, 63.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 460)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 608, 1652)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4634)
[M::mem_pestat] mean and std.dev: (896.06, 867.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6125)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 291, 794)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2030)
[M::mem_pestat] mean and std.dev: (441.97, 413.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2648)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 762984 sequences (100000100 bp) in 2.160 CPU sec, 2.160 real sec...
[M::mem_process_seqs] Processed 768536 reads in 214.260 CPU sec, 6.799 real sec
sorting block 110, #reads = 1102430 mem = 536883769 peak = 873906176
[M::mem_process_seqs] Processed 766252 reads in 141.660 CPU sec, 4.501 real sec
sorting block 111, #reads = 1118852 mem = 536878336 peak = 873906176
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 306729, 16, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 279, 1207)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3313)
[M::mem_pestat] mean and std.dev: (746.70, 889.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4366)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (112, 150, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 379)
[M::mem_pestat] mean and std.dev: (160.85, 64.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 468)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (119, 383, 952)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2618)
[M::mem_pestat] mean and std.dev: (453.27, 466.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3451)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 271, 515)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1197)
[M::mem_pestat] mean and std.dev: (358.00, 252.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1538)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 761400 sequences (100000110 bp) in 3.214 CPU sec, 3.431 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 306371, 26, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (144, 184, 274)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 534)
[M::mem_pestat] mean and std.dev: (184.59, 87.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 664)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (113, 150, 203)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 383)
[M::mem_pestat] mean and std.dev: (162.15, 65.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 473)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 470, 1158)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3108)
[M::mem_pestat] mean and std.dev: (638.09, 703.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4083)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 336, 1005)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2699)
[M::mem_pestat] mean and std.dev: (600.83, 520.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3546)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 760324 sequences (100000055 bp) in 2.178 CPU sec, 2.178 real sec...
[M::mem_process_seqs] Processed 764904 reads in 204.725 CPU sec, 6.519 real sec
[M::mem_process_seqs] Processed 762984 reads in 136.839 CPU sec, 4.346 real sec
sorting block 112, #reads = 1117156 mem = 536885956 peak = 873906176
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 305798, 12, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 226, 919)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2463)
[M::mem_pestat] mean and std.dev: (505.18, 631.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3235)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (113, 152, 204)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 386)
[M::mem_pestat] mean and std.dev: (163.29, 66.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 477)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 811, 2250)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6318)
[M::mem_pestat] mean and std.dev: (847.91, 772.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8352)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 332, 1406)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3766)
[M::mem_pestat] mean and std.dev: (650.58, 619.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4946)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 760224 sequences (100000196 bp) in 3.449 CPU sec, 3.667 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 305571, 28, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 225, 500)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1204)
[M::mem_pestat] mean and std.dev: (297.15, 253.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1556)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (114, 152, 205)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 387)
[M::mem_pestat] mean and std.dev: (163.98, 66.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 478)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 617, 1405)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3901)
[M::mem_pestat] mean and std.dev: (662.28, 627.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5149)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 625, 758)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1856)
[M::mem_pestat] mean and std.dev: (434.36, 283.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2405)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 758572 sequences (100000058 bp) in 2.180 CPU sec, 2.178 real sec...
[M::mem_process_seqs] Processed 761400 reads in 202.243 CPU sec, 6.433 real sec
sorting block 113, #reads = 1116962 mem = 536878391 peak = 873906176
[M::mem_process_seqs] Processed 760324 reads in 135.908 CPU sec, 4.322 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 305305, 27, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 359, 744)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1904)
[M::mem_pestat] mean and std.dev: (491.14, 426.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2484)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (113, 153, 207)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 395)
[M::mem_pestat] mean and std.dev: (165.01, 68.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 489)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 475, 4512)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13098)
[M::mem_pestat] mean and std.dev: (2562.48, 3115.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17391)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 186, 463)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1085)
[M::mem_pestat] mean and std.dev: (276.24, 205.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1396)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 114, #reads = 1115794 mem = 536879994 peak = 873906176
[M::process] read 758912 sequences (100000024 bp) in 3.286 CPU sec, 3.491 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 304707, 18, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (277, 524, 1985)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5401)
[M::mem_pestat] mean and std.dev: (1069.58, 1113.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7109)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (114, 154, 208)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 396)
[M::mem_pestat] mean and std.dev: (165.82, 68.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 490)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 540, 725)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1759)
[M::mem_pestat] mean and std.dev: (398.93, 275.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2276)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 320, 606)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1490)
[M::mem_pestat] mean and std.dev: (365.18, 262.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1932)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 760224 reads in 200.028 CPU sec, 6.364 real sec
[M::process] read 758088 sequences (100000108 bp) in 2.132 CPU sec, 2.138 real sec...
[M::mem_process_seqs] Processed 758572 reads in 135.159 CPU sec, 4.281 real sec
sorting block 115, #reads = 1116343 mem = 536878662 peak = 873906176
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 304573, 21, 19)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (135, 209, 809)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2157)
[M::mem_pestat] mean and std.dev: (402.10, 376.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2831)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (114, 153, 207)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 393)
[M::mem_pestat] mean and std.dev: (165.29, 67.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 486)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (265, 513, 1589)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4237)
[M::mem_pestat] mean and std.dev: (883.05, 799.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5561)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 211, 571)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1363)
[M::mem_pestat] mean and std.dev: (356.06, 280.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1759)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 757224 sequences (100000126 bp) in 3.426 CPU sec, 3.564 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 304667, 26, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (135, 252, 1074)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2952)
[M::mem_pestat] mean and std.dev: (586.84, 746.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3891)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (114, 154, 208)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 396)
[M::mem_pestat] mean and std.dev: (166.06, 68.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 490)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (142, 1234, 3836)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 11224)
[M::mem_pestat] mean and std.dev: (2047.77, 2079.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14918)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 342, 1357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3699)
[M::mem_pestat] mean and std.dev: (570.08, 667.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4870)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 757316 sequences (100000087 bp) in 2.163 CPU sec, 2.166 real sec...
[M::mem_process_seqs] Processed 758912 reads in 205.889 CPU sec, 6.537 real sec
[M::mem_process_seqs] Processed 758088 reads in 138.472 CPU sec, 4.412 real sec
sorting block 116, #reads = 1115448 mem = 536877613 peak = 873906176
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 304648, 22, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (131, 209, 471)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1151)
[M::mem_pestat] mean and std.dev: (260.36, 222.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1491)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (115, 154, 209)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 397)
[M::mem_pestat] mean and std.dev: (166.62, 68.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 491)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 517, 1256)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3456)
[M::mem_pestat] mean and std.dev: (723.95, 831.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4556)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 329, 905)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2369)
[M::mem_pestat] mean and std.dev: (491.76, 444.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3101)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 753938 sequences (100000156 bp) in 3.080 CPU sec, 3.226 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 303825, 25, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (253, 342, 850)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2044)
[M::mem_pestat] mean and std.dev: (463.49, 417.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2641)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (115, 154, 208)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 394)
[M::mem_pestat] mean and std.dev: (166.03, 67.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 487)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (72, 729, 2105)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6171)
[M::mem_pestat] mean and std.dev: (965.88, 1125.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8204)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 361, 1509)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4117)
[M::mem_pestat] mean and std.dev: (805.86, 962.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5421)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 752274 sequences (100000060 bp) in 2.114 CPU sec, 2.123 real sec...
[M::mem_process_seqs] Processed 757224 reads in 205.236 CPU sec, 6.544 real sec
sorting block 117, #reads = 1114685 mem = 536880187 peak = 873906176
[M::mem_process_seqs] Processed 757316 reads in 140.604 CPU sec, 4.464 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 303358, 22, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 399, 1254)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3466)
[M::mem_pestat] mean and std.dev: (673.41, 722.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4572)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (116, 157, 213)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 407)
[M::mem_pestat] mean and std.dev: (169.40, 70.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 504)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (425, 508, 1018)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2204)
[M::mem_pestat] mean and std.dev: (646.40, 472.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2797)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 381, 673)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1607)
[M::mem_pestat] mean and std.dev: (438.72, 332.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2074)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 118, #reads = 1116394 mem = 536879501 peak = 873906176
[M::process] read 751110 sequences (100000065 bp) in 3.332 CPU sec, 3.473 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 302749, 18, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (141, 236, 1164)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3210)
[M::mem_pestat] mean and std.dev: (554.82, 648.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4233)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 158, 214)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 408)
[M::mem_pestat] mean and std.dev: (170.44, 70.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 505)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (299, 765, 1423)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3671)
[M::mem_pestat] mean and std.dev: (753.20, 628.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4795)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 219, 1154)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3170)
[M::mem_pestat] mean and std.dev: (579.94, 763.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4178)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 750528 sequences (100000212 bp) in 2.236 CPU sec, 2.237 real sec...
[M::mem_process_seqs] Processed 753938 reads in 205.813 CPU sec, 6.556 real sec
[M::mem_process_seqs] Processed 752274 reads in 139.164 CPU sec, 4.422 real sec
sorting block 119, #reads = 1112694 mem = 536882380 peak = 873906176
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 302370, 18, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 278, 677)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1681)
[M::mem_pestat] mean and std.dev: (398.80, 359.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2183)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 159, 215)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 411)
[M::mem_pestat] mean and std.dev: (171.36, 71.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 509)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (243, 655, 719)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1671)
[M::mem_pestat] mean and std.dev: (463.73, 292.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2147)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 262, 488)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1100)
[M::mem_pestat] mean and std.dev: (262.40, 115.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1406)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 749986 sequences (100000172 bp) in 3.371 CPU sec, 3.514 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 302194, 19, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (136, 248, 379)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 865)
[M::mem_pestat] mean and std.dev: (241.34, 170.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1108)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (117, 159, 215)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 411)
[M::mem_pestat] mean and std.dev: (171.56, 71.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 509)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (60, 134, 1305)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3795)
[M::mem_pestat] mean and std.dev: (524.22, 624.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5040)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 378, 868)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2194)
[M::mem_pestat] mean and std.dev: (519.83, 444.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2857)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 749038 sequences (100000142 bp) in 2.189 CPU sec, 2.192 real sec...
[M::mem_process_seqs] Processed 751110 reads in 201.307 CPU sec, 6.407 real sec
[M::mem_process_seqs] Processed 750528 reads in 136.298 CPU sec, 4.329 real sec
sorting block 120, #reads = 1112110 mem = 536879410 peak = 873906176
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 301226, 20, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (135, 202, 844)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2262)
[M::mem_pestat] mean and std.dev: (359.91, 465.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2971)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 159, 216)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 412)
[M::mem_pestat] mean and std.dev: (171.71, 71.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 510)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (74, 322, 859)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2429)
[M::mem_pestat] mean and std.dev: (382.79, 350.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3214)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 453, 667)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1649)
[M::mem_pestat] mean and std.dev: (445.16, 313.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2140)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 748430 sequences (100000239 bp) in 3.154 CPU sec, 3.304 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 301563, 30, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 277, 870)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2298)
[M::mem_pestat] mean and std.dev: (419.42, 413.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3012)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 160, 217)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 415)
[M::mem_pestat] mean and std.dev: (172.87, 72.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 514)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 458, 990)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2656)
[M::mem_pestat] mean and std.dev: (418.92, 348.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3489)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (242, 359, 1174)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3038)
[M::mem_pestat] mean and std.dev: (663.10, 627.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3970)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 749986 reads in 201.890 CPU sec, 6.451 real sec
sorting block 121, #reads = 1112620 mem = 536888795 peak = 873906176
[M::process] read 749262 sequences (100000217 bp) in 2.334 CPU sec, 2.369 real sec...
[M::mem_process_seqs] Processed 749038 reads in 139.245 CPU sec, 4.426 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 301663, 28, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 558, 1112)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2918)
[M::mem_pestat] mean and std.dev: (717.68, 646.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3821)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 160, 217)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 415)
[M::mem_pestat] mean and std.dev: (173.03, 71.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 514)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (276, 553, 1411)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3681)
[M::mem_pestat] mean and std.dev: (750.85, 688.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4816)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 274, 1067)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2793)
[M::mem_pestat] mean and std.dev: (602.33, 575.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3656)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 122, #reads = 1111340 mem = 536879203 peak = 873906176
[M::process] read 748546 sequences (100000050 bp) in 3.658 CPU sec, 3.859 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 301380, 25, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (138, 289, 841)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2247)
[M::mem_pestat] mean and std.dev: (452.93, 473.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2950)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 160, 216)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 412)
[M::mem_pestat] mean and std.dev: (172.06, 71.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 510)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (250, 934, 1649)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4447)
[M::mem_pestat] mean and std.dev: (791.90, 594.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5846)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 274, 420)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 914)
[M::mem_pestat] mean and std.dev: (292.00, 181.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1161)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 748430 reads in 195.683 CPU sec, 6.261 real sec
[M::mem_process_seqs] Processed 749262 reads in 132.480 CPU sec, 4.193 real sec
[M::process] read 748292 sequences (100000297 bp) in 2.417 CPU sec, 2.518 real sec...
sorting block 123, #reads = 1110960 mem = 536881153 peak = 873906176
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 301440, 28, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 217, 457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1061)
[M::mem_pestat] mean and std.dev: (245.03, 174.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1363)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 160, 218)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 418)
[M::mem_pestat] mean and std.dev: (173.26, 72.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 518)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 299, 925)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2405)
[M::mem_pestat] mean and std.dev: (555.27, 595.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3145)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 397, 731)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1751)
[M::mem_pestat] mean and std.dev: (420.33, 305.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2261)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 598266 sequences (79791341 bp) in 3.157 CPU sec, 3.297 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 301468, 21, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (140, 161, 392)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 896)
[M::mem_pestat] mean and std.dev: (194.88, 139.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1148)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 160, 218)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 418)
[M::mem_pestat] mean and std.dev: (173.22, 72.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 518)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (131, 636, 1020)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2798)
[M::mem_pestat] mean and std.dev: (611.26, 542.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3687)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 656, 2488)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7096)
[M::mem_pestat] mean and std.dev: (1379.72, 1621.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9400)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 748546 reads in 184.912 CPU sec, 5.965 real sec
sorting block 124, #reads = 1113211 mem = 536885302 peak = 873906176
[M::mem_process_seqs] Processed 748292 reads in 123.307 CPU sec, 3.960 real sec
sorting block 125, #reads = 1112057 mem = 536879381 peak = 873906176
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 240627, 13, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 232, 274)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 490)
[M::mem_pestat] mean and std.dev: (198.88, 69.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 598)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (118, 159, 216)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 412)
[M::mem_pestat] mean and std.dev: (171.93, 71.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 510)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (146, 594, 1418)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3962)
[M::mem_pestat] mean and std.dev: (784.69, 629.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5234)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (122, 346, 1380)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3896)
[M::mem_pestat] mean and std.dev: (539.14, 548.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5154)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 598266 reads in 91.410 CPU sec, 3.038 real sec
os version: Linux 6.12.88
cpu vendor: GenuineIntel
signature: 000a06d1
features: 1f8bfbff fffab20b
extended: f1bf27eb 1b407f7e
amd bits: 2c100800 00000121
brand: Intel(R) Xeon(R) 6975P-C
threads: 31
algo: bwa-mem
license: sentieon:klib=31
reads: 140012718
overall: 70693937152 mem 22510.869 user 830.111 sys 767.077 real
[main] Version: 0.7.17-r1188
[main] CMD: /opt/conda/share/sentieon-202308.03-3/libexec/bwa mem -K 100000000 -Y -R @RG\tID:A23MHWWLT4.659_dm4-T1-TDNA-1_A23MHWWLT4_1.L004\tPU:L004\tSM:659_dm4-T1-TDNA-1_A23MHWWLT4_1\tLB:659_dm4-T1-TDNA-1_A23MHWWLT4_1\tDS:s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta\tPL:ILLUMINA -t 31 ./BWAIndex/Homo_sapiens_assembly38.fasta.64 659_dm4-T1-TDNA-1_A23MHWWLT4_1_R1.fastq.gz 659_dm4-T1-TDNA-1_A23MHWWLT4_1_R2.fastq.gz
[main] Real time: 767.118 sec; CPU: 23340.994 sec
sorting block 126, #reads = 651170 mem = 315202427 peak = 873906176
uniq header count 1
merging 127 blocks
sw version: sentieon-genomics-202308.03
os version: Linux 6.12.88
cpu vendor: GenuineIntel
signature: 000a06d1
features: 1f8bfbff fffab20b
extended: f1bf27eb 1b407f7e
amd bits: 2c100800 00000121
brand: Intel(R) Xeon(R) 6975P-C
threads: 31 max 384
algo: util-sort
license: sentieon:util=1
output file size: 7305258763
output reads: 141229496
bam_mem_sort: 127 calls 103.450 user 3.104 sys 107.732 real
bam_write: 127 calls 77.338 user 6.575 sys 135.284 real
execute: 1 calls 45.150 user 2.656 sys 817.510 real
merge_files: 1 calls 45.114 user 2.642 sys 49.955 real
parse_chunk: 2026 calls 96.650 user 27.012 sys 143.187 real
read_chunk: 5503 calls 64.684 user 30.770 sys 690.379 real
sort_block: 1 calls 48.122 user 29.744 sys 666.583 real
write_chunk: 3475 calls 44.679 user 2.244 sys 48.769 real
overall: 3362545664 mem 1932.243 user 101.030 sys 817.526 real
ls: cannot access '*.cram': No such file or directory