File Info

Filename
.command.log
Full Path
s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/ed/46c339da68ccad747be84c940d47c4/.command.log
Size
444.0 KB
Task
DAQ:SENTIEON_BWAMEM (1029_FRC-T1-TDNA-1_A23MHWWLT4_1;L002;0001)
Attempt

Content

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  Downloading: s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/af/7a7ff1945fb946f58194bf22a331eb/1029_FRC-T1-TDNA-1_A23MHWWLT4_1/1029_FRC-T1-TDNA-1_A23MHWWLT4_1_R2.fastq.gz
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/ed/46c339da68ccad747be84c940d47c4/.command.sh
  Downloading: s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta.fai
  Downloading: s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/BWAIndex
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/ed/46c339da68ccad747be84c940d47c4/.command.run
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/af/7a7ff1945fb946f58194bf22a331eb/1029_FRC-T1-TDNA-1_A23MHWWLT4_1/1029_FRC-T1-TDNA-1_A23MHWWLT4_1_R1.fastq.gz
==> STAGING COMPLETE (7 inputs)

cmdline: /opt/conda/share/sentieon-202308.03-3/libexec/util sort -r Homo_sapiens_assembly38.fasta -t 31 -o 1029_FRC-T1-TDNA-1_A23MHWWLT4_1.bam --sam2bam -
This software is licensed to bgold@natera.com by Sentieon Inc.
This software is licensed to bgold@natera.com by Sentieon Inc.
version: sentieon-genomics-202308.03
[M::bwa_idx_load_from_disk] read 3171 ALT contigs
[M::main_mem] bwa index loaded in 1931.228 CPU sec, 70.662 real sec
[M::process] read 696402 sequences (100000063 bp) in 1.026 CPU sec, 1.028 real sec...
[M::process] read 695054 sequences (100000078 bp) in 1.590 CPU sec, 1.600 real sec...
[M::process] read 694022 sequences (100000121 bp) in 1.787 CPU sec, 1.837 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 282705, 12, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (243, 323, 510)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1044)
[M::mem_pestat] mean and std.dev: (304.68, 129.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1311)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 262, 377)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 789)
[M::mem_pestat] mean and std.dev: (284.96, 142.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 995)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (418, 476, 4016)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 11212)
[M::mem_pestat] mean and std.dev: (2120.75, 2975.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14810)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (248, 316, 1248)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3248)
[M::mem_pestat] mean and std.dev: (697.05, 651.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4248)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 693352 sequences (100000226 bp) in 1.573 CPU sec, 1.626 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 283010, 17, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (132, 171, 293)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 615)
[M::mem_pestat] mean and std.dev: (181.64, 72.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 776)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 268, 386)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 810)
[M::mem_pestat] mean and std.dev: (290.94, 146.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1022)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (371, 589, 3449)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9605)
[M::mem_pestat] mean and std.dev: (1515.76, 1982.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12683)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 377, 1026)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2634)
[M::mem_pestat] mean and std.dev: (581.58, 542.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3438)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696402 reads in 213.911 CPU sec, 6.997 real sec
[M::mem_process_seqs] Processed 695054 reads in 130.282 CPU sec, 4.314 real sec
sorting block 0, #reads = 1076391 mem = 536877673 peak = 592023552
[M::process] read 692792 sequences (100000260 bp) in 1.996 CPU sec, 2.155 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 282319, 6, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 324, 575)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1419)
[M::mem_pestat] mean and std.dev: (367.05, 245.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1841)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 271, 388)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 812)
[M::mem_pestat] mean and std.dev: (293.03, 146.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1024)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (305, 502, 2128)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5774)
[M::mem_pestat] mean and std.dev: (1132.70, 1253.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7597)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 692354 sequences (100000078 bp) in 1.690 CPU sec, 1.731 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 282579, 24, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 268, 408)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 820)
[M::mem_pestat] mean and std.dev: (270.75, 120.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1026)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 274, 393)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 823)
[M::mem_pestat] mean and std.dev: (296.48, 148.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1038)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (621, 1387, 2332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5754)
[M::mem_pestat] mean and std.dev: (1338.83, 1065.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7465)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (235, 333, 1385)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3685)
[M::mem_pestat] mean and std.dev: (681.76, 868.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4835)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 282263, 16, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 249, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 698)
[M::mem_pestat] mean and std.dev: (260.96, 118.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 864)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 276, 395)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 827)
[M::mem_pestat] mean and std.dev: (297.85, 148.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1043)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 845, 3250)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9400)
[M::mem_pestat] mean and std.dev: (1665.94, 2119.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12475)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (236, 333, 775)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1853)
[M::mem_pestat] mean and std.dev: (447.73, 325.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2392)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 694022 reads in 273.356 CPU sec, 8.972 real sec
[M::mem_process_seqs] Processed 693352 reads in 211.905 CPU sec, 7.017 real sec
[M::mem_process_seqs] Processed 692792 reads in 234.866 CPU sec, 7.780 real sec
sorting block 1, #reads = 1076867 mem = 536876692 peak = 720998400
[M::process] read 691924 sequences (100000262 bp) in 2.221 CPU sec, 2.444 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 281714, 14, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 321, 1909)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5371)
[M::mem_pestat] mean and std.dev: (726.30, 807.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7102)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 278, 398)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 834)
[M::mem_pestat] mean and std.dev: (300.30, 150.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1052)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (658, 1128, 9941)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 28507)
[M::mem_pestat] mean and std.dev: (4144.79, 4231.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 37790)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 291, 400)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 778)
[M::mem_pestat] mean and std.dev: (314.50, 143.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 967)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 2, #reads = 1076362 mem = 536879535 peak = 887029760
[M::process] read 691778 sequences (100000090 bp) in 2.218 CPU sec, 2.423 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 281858, 26, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (329, 429, 1203)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2951)
[M::mem_pestat] mean and std.dev: (795.97, 818.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4070)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 280, 401)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 841)
[M::mem_pestat] mean and std.dev: (302.24, 151.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1061)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (393, 1572, 3271)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9027)
[M::mem_pestat] mean and std.dev: (2513.85, 2307.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11905)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 307, 472)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1072)
[M::mem_pestat] mean and std.dev: (319.54, 185.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1372)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 691636 sequences (100000153 bp) in 1.772 CPU sec, 1.842 real sec...
[M::mem_process_seqs] Processed 692354 reads in 198.426 CPU sec, 6.421 real sec
[M::mem_process_seqs] Processed 691924 reads in 133.131 CPU sec, 4.340 real sec
sorting block 3, #reads = 1077180 mem = 536880446 peak = 887029760
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 281844, 22, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 389, 2516)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7232)
[M::mem_pestat] mean and std.dev: (1181.09, 1428.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9590)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 282, 404)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 848)
[M::mem_pestat] mean and std.dev: (304.12, 151.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1070)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (411, 592, 947)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2019)
[M::mem_pestat] mean and std.dev: (644.29, 359.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2555)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 221, 1219)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3283)
[M::mem_pestat] mean and std.dev: (556.58, 582.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4315)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 691162 sequences (100000016 bp) in 2.216 CPU sec, 2.458 real sec...
[M::process] read 690540 sequences (100000137 bp) in 1.609 CPU sec, 1.620 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 282371, 16, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (240, 307, 1009)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2547)
[M::mem_pestat] mean and std.dev: (493.71, 396.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3316)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 283, 405)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 851)
[M::mem_pestat] mean and std.dev: (304.78, 152.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1074)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (475, 588, 1256)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2818)
[M::mem_pestat] mean and std.dev: (720.33, 501.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3599)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 278, 346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 668)
[M::mem_pestat] mean and std.dev: (263.27, 116.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 829)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 691778 reads in 197.344 CPU sec, 6.479 real sec
[M::mem_process_seqs] Processed 691636 reads in 131.855 CPU sec, 4.281 real sec
sorting block 4, #reads = 1076615 mem = 536879773 peak = 887029760
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 282303, 22, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 289, 620)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1552)
[M::mem_pestat] mean and std.dev: (400.73, 284.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2018)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 284, 407)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 855)
[M::mem_pestat] mean and std.dev: (306.27, 152.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1079)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (541, 1565, 2016)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4966)
[M::mem_pestat] mean and std.dev: (1269.45, 1068.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6441)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (253, 334, 989)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2461)
[M::mem_pestat] mean and std.dev: (509.20, 415.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3197)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 690430 sequences (100000068 bp) in 2.425 CPU sec, 2.633 real sec...
[M::process] read 690314 sequences (100000281 bp) in 1.786 CPU sec, 1.795 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 281600, 22, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 351, 506)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1144)
[M::mem_pestat] mean and std.dev: (360.48, 210.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1463)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 286, 410)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 860)
[M::mem_pestat] mean and std.dev: (308.23, 153.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1085)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (475, 805, 5519)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 15607)
[M::mem_pestat] mean and std.dev: (3127.09, 3967.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 20651)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 379, 927)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2343)
[M::mem_pestat] mean and std.dev: (562.00, 512.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3051)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 691162 reads in 195.172 CPU sec, 6.385 real sec
sorting block 5, #reads = 1076287 mem = 536880906 peak = 887029760
[M::mem_process_seqs] Processed 690540 reads in 128.763 CPU sec, 4.205 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 281424, 19, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 315, 769)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1965)
[M::mem_pestat] mean and std.dev: (393.24, 290.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2563)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 287, 410)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 858)
[M::mem_pestat] mean and std.dev: (309.00, 153.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1082)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (343, 524, 1232)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3010)
[M::mem_pestat] mean and std.dev: (607.89, 452.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3899)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 277, 574)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1354)
[M::mem_pestat] mean and std.dev: (314.90, 231.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1744)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 6, #reads = 1074937 mem = 536879888 peak = 887029760
[M::process] read 690270 sequences (100000173 bp) in 2.639 CPU sec, 2.879 real sec...
[M::process] read 690274 sequences (100000249 bp) in 1.772 CPU sec, 1.796 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 281235, 17, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 244, 595)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1459)
[M::mem_pestat] mean and std.dev: (321.36, 267.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1891)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 285, 409)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 857)
[M::mem_pestat] mean and std.dev: (307.95, 153.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1081)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (599, 1477, 5178)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 14336)
[M::mem_pestat] mean and std.dev: (2046.65, 1836.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 18915)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (248, 394, 561)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1187)
[M::mem_pestat] mean and std.dev: (399.76, 213.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1500)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 690430 reads in 199.433 CPU sec, 6.566 real sec
[M::mem_process_seqs] Processed 690314 reads in 128.340 CPU sec, 4.241 real sec
sorting block 7, #reads = 1074174 mem = 536885021 peak = 887029760
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 281043, 20, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 301, 510)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1068)
[M::mem_pestat] mean and std.dev: (318.87, 166.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1347)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 286, 408)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 854)
[M::mem_pestat] mean and std.dev: (307.95, 153.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1077)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (476, 1499, 2828)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7532)
[M::mem_pestat] mean and std.dev: (1523.68, 1278.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9884)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 259, 952)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2496)
[M::mem_pestat] mean and std.dev: (424.14, 364.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3268)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 690154 sequences (100000107 bp) in 2.838 CPU sec, 3.058 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 280742, 17, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (227, 322, 427)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 827)
[M::mem_pestat] mean and std.dev: (315.07, 137.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1027)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 286, 409)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 857)
[M::mem_pestat] mean and std.dev: (308.18, 153.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1081)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (105, 131, 420)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1050)
[M::mem_pestat] mean and std.dev: (191.20, 140.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1365)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (292, 409, 2152)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5872)
[M::mem_pestat] mean and std.dev: (997.66, 962.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7732)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 690476 sequences (100000191 bp) in 1.885 CPU sec, 1.910 real sec...
[M::mem_process_seqs] Processed 690270 reads in 195.490 CPU sec, 6.373 real sec
[M::mem_process_seqs] Processed 690274 reads in 128.425 CPU sec, 4.225 real sec
sorting block 8, #reads = 1075715 mem = 536879374 peak = 887029760
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 281213, 12, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 333, 552)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1342)
[M::mem_pestat] mean and std.dev: (353.69, 238.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1737)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 285, 408)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 854)
[M::mem_pestat] mean and std.dev: (307.72, 153.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1077)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (291, 863, 2650)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7368)
[M::mem_pestat] mean and std.dev: (1241.45, 1381.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9727)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 324, 498)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1134)
[M::mem_pestat] mean and std.dev: (355.39, 212.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1452)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 690456 sequences (100000135 bp) in 2.532 CPU sec, 2.840 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23, 281401, 29, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 200, 476)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1100)
[M::mem_pestat] mean and std.dev: (351.86, 279.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1470)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 282, 405)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 847)
[M::mem_pestat] mean and std.dev: (305.10, 152.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1068)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (572, 869, 1488)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3320)
[M::mem_pestat] mean and std.dev: (931.77, 557.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4236)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 265, 457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 955)
[M::mem_pestat] mean and std.dev: (305.22, 157.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1204)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 690422 sequences (100000285 bp) in 1.811 CPU sec, 1.837 real sec...
[M::mem_process_seqs] Processed 690154 reads in 197.390 CPU sec, 6.460 real sec
sorting block 9, #reads = 1073424 mem = 536889000 peak = 887029760
[M::mem_process_seqs] Processed 690476 reads in 128.125 CPU sec, 4.113 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 281274, 13, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 272, 511)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1221)
[M::mem_pestat] mean and std.dev: (303.62, 201.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1576)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 282, 403)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 841)
[M::mem_pestat] mean and std.dev: (304.63, 151.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1060)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (515, 631, 1066)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2168)
[M::mem_pestat] mean and std.dev: (668.31, 422.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2719)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (238, 331, 633)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1423)
[M::mem_pestat] mean and std.dev: (395.26, 216.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1818)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 10, #reads = 1074641 mem = 536883838 peak = 887029760
[M::process] read 690796 sequences (100000265 bp) in 2.790 CPU sec, 3.067 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 281178, 19, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 277, 614)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1414)
[M::mem_pestat] mean and std.dev: (403.79, 257.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1814)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 282, 404)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 844)
[M::mem_pestat] mean and std.dev: (304.61, 151.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1064)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (570, 1507, 1845)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4395)
[M::mem_pestat] mean and std.dev: (1043.88, 715.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5670)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (233, 501, 1399)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3731)
[M::mem_pestat] mean and std.dev: (668.34, 728.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4897)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 690518 sequences (100000103 bp) in 1.993 CPU sec, 2.005 real sec...
[M::mem_process_seqs] Processed 690456 reads in 201.801 CPU sec, 6.564 real sec
[M::mem_process_seqs] Processed 690422 reads in 132.581 CPU sec, 4.233 real sec
sorting block 11, #reads = 1074367 mem = 536878951 peak = 887029760
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 281308, 15, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 319, 845)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2169)
[M::mem_pestat] mean and std.dev: (401.91, 449.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2831)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 281, 402)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 840)
[M::mem_pestat] mean and std.dev: (303.65, 150.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1059)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (223, 402, 4210)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12184)
[M::mem_pestat] mean and std.dev: (1409.93, 1724.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 16171)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 277, 1007)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2623)
[M::mem_pestat] mean and std.dev: (702.98, 774.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3801)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 690370 sequences (100000093 bp) in 2.657 CPU sec, 2.879 real sec...
[M::process] read 690240 sequences (100000205 bp) in 1.779 CPU sec, 1.792 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 281543, 6, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 238, 382)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 834)
[M::mem_pestat] mean and std.dev: (284.60, 203.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1097)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 282, 403)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 843)
[M::mem_pestat] mean and std.dev: (304.78, 151.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1063)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 332, 551)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1315)
[M::mem_pestat] mean and std.dev: (404.96, 319.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1697)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 690796 reads in 194.307 CPU sec, 6.254 real sec
[M::mem_process_seqs] Processed 690518 reads in 129.522 CPU sec, 4.411 real sec
sorting block 12, #reads = 1073826 mem = 536878089 peak = 887029760
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 281435, 23, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 346, 597)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1457)
[M::mem_pestat] mean and std.dev: (349.80, 261.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1887)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 283, 405)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 847)
[M::mem_pestat] mean and std.dev: (305.62, 151.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1068)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (401, 818, 2469)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6605)
[M::mem_pestat] mean and std.dev: (1092.60, 1373.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8673)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 295, 456)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 936)
[M::mem_pestat] mean and std.dev: (341.21, 172.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1176)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 689916 sequences (100000034 bp) in 2.895 CPU sec, 3.232 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 280668, 7, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 405, 949)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2385)
[M::mem_pestat] mean and std.dev: (557.80, 460.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3103)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 284, 406)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 850)
[M::mem_pestat] mean and std.dev: (306.02, 151.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1072)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 478, 901)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2329)
[M::mem_pestat] mean and std.dev: (519.40, 501.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3043)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 689602 sequences (100000178 bp) in 1.978 CPU sec, 1.979 real sec...
[M::mem_process_seqs] Processed 690370 reads in 198.722 CPU sec, 6.672 real sec
[M::mem_process_seqs] Processed 690240 reads in 131.767 CPU sec, 4.283 real sec
sorting block 13, #reads = 1075366 mem = 536880748 peak = 887029760
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 280816, 8, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 289, 559)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1241)
[M::mem_pestat] mean and std.dev: (348.84, 231.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1582)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 284, 404)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 842)
[M::mem_pestat] mean and std.dev: (305.68, 151.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1061)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 360, 679)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1643)
[M::mem_pestat] mean and std.dev: (312.70, 176.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2125)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 688428 sequences (100000254 bp) in 2.632 CPU sec, 2.975 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 281090, 24, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 204, 997)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2681)
[M::mem_pestat] mean and std.dev: (569.42, 690.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3523)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 285, 405)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 843)
[M::mem_pestat] mean and std.dev: (306.36, 150.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1062)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (133, 1129, 1900)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5434)
[M::mem_pestat] mean and std.dev: (993.21, 852.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7201)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 271, 474)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 970)
[M::mem_pestat] mean and std.dev: (304.58, 173.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1218)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 689226 sequences (100000175 bp) in 1.742 CPU sec, 1.785 real sec...
[M::mem_process_seqs] Processed 689916 reads in 192.819 CPU sec, 6.245 real sec
sorting block 14, #reads = 1073720 mem = 536878742 peak = 887029760
[M::mem_process_seqs] Processed 689602 reads in 128.895 CPU sec, 4.156 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 281051, 37, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (238, 359, 676)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1552)
[M::mem_pestat] mean and std.dev: (357.26, 205.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1990)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 293, 414)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 860)
[M::mem_pestat] mean and std.dev: (313.17, 153.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1083)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (84, 402, 1323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3801)
[M::mem_pestat] mean and std.dev: (733.19, 817.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5040)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (255, 354, 564)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1182)
[M::mem_pestat] mean and std.dev: (371.90, 207.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1491)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 15, #reads = 1073249 mem = 536876696 peak = 887029760
[M::process] read 689214 sequences (100000241 bp) in 2.682 CPU sec, 2.913 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 280883, 32, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 375, 1074)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2828)
[M::mem_pestat] mean and std.dev: (594.17, 633.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3705)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::process] read 689098 sequences (100000285 bp) in 1.655 CPU sec, 1.694 real sec...
[M::mem_pestat] (25, 50, 75) percentile: (187, 286, 405)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 841)
[M::mem_pestat] mean and std.dev: (307.07, 150.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1059)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (356, 710, 2218)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5942)
[M::mem_pestat] mean and std.dev: (1094.00, 1055.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7804)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (230, 401, 472)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 956)
[M::mem_pestat] mean and std.dev: (324.28, 145.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1198)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 688428 reads in 194.304 CPU sec, 6.491 real sec
[M::mem_process_seqs] Processed 689226 reads in 127.845 CPU sec, 4.172 real sec
sorting block 16, #reads = 1075015 mem = 536875634 peak = 887029760
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 280309, 19, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 308, 406)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 872)
[M::mem_pestat] mean and std.dev: (299.80, 202.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1108)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 287, 406)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 842)
[M::mem_pestat] mean and std.dev: (307.30, 150.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1060)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 579, 869)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2209)
[M::mem_pestat] mean and std.dev: (600.74, 425.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2879)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (265, 381, 795)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1855)
[M::mem_pestat] mean and std.dev: (466.86, 324.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2385)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 689000 sequences (100000135 bp) in 2.809 CPU sec, 3.091 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 280977, 20, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 217, 630)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1530)
[M::mem_pestat] mean and std.dev: (357.34, 301.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1980)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 288, 404)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 836)
[M::mem_pestat] mean and std.dev: (307.23, 149.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1052)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (259, 471, 3222)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9148)
[M::mem_pestat] mean and std.dev: (2212.70, 2955.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14033)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 224, 485)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1075)
[M::mem_pestat] mean and std.dev: (290.19, 212.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1370)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 688644 sequences (100000211 bp) in 1.741 CPU sec, 1.749 real sec...
[M::mem_process_seqs] Processed 689214 reads in 194.851 CPU sec, 6.352 real sec
[M::mem_process_seqs] Processed 689098 reads in 129.114 CPU sec, 4.224 real sec
sorting block 17, #reads = 1073389 mem = 536880227 peak = 887029760
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 280329, 13, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 273, 1124)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2976)
[M::mem_pestat] mean and std.dev: (555.25, 530.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3902)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 287, 403)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 833)
[M::mem_pestat] mean and std.dev: (307.03, 149.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1048)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (64, 523, 1787)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5233)
[M::mem_pestat] mean and std.dev: (786.69, 933.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6956)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (257, 416, 690)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1556)
[M::mem_pestat] mean and std.dev: (461.00, 306.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1989)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 688556 sequences (100000170 bp) in 2.776 CPU sec, 3.176 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 280801, 16, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (244, 350, 784)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1864)
[M::mem_pestat] mean and std.dev: (485.24, 394.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2404)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 290, 407)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 841)
[M::mem_pestat] mean and std.dev: (309.10, 150.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1058)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 605, 1210)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3258)
[M::mem_pestat] mean and std.dev: (563.50, 470.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4282)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (270, 288, 825)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1935)
[M::mem_pestat] mean and std.dev: (414.22, 285.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2490)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 688138 sequences (100000075 bp) in 1.971 CPU sec, 1.981 real sec...
[M::mem_process_seqs] Processed 689000 reads in 194.561 CPU sec, 6.418 real sec
sorting block 18, #reads = 1074072 mem = 536880205 peak = 887029760
[M::mem_process_seqs] Processed 688644 reads in 127.937 CPU sec, 4.191 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 281162, 13, 82)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 266, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 590)
[M::mem_pestat] mean and std.dev: (243.76, 86.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 721)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 291, 409)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 847)
[M::mem_pestat] mean and std.dev: (310.80, 151.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1066)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (83, 297, 1725)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5009)
[M::mem_pestat] mean and std.dev: (505.45, 515.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6651)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (253, 360, 564)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1186)
[M::mem_pestat] mean and std.dev: (346.61, 151.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1497)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 19, #reads = 1073142 mem = 536880460 peak = 904036352
[M::process] read 687804 sequences (100000123 bp) in 2.902 CPU sec, 3.158 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 280624, 13, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 277, 355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 671)
[M::mem_pestat] mean and std.dev: (273.24, 118.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 829)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 294, 412)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 852)
[M::mem_pestat] mean and std.dev: (312.92, 152.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1072)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (550, 550, 4257)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 11671)
[M::mem_pestat] mean and std.dev: (1304.46, 1627.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 15378)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (263, 410, 1432)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3770)
[M::mem_pestat] mean and std.dev: (784.29, 637.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4939)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 688556 reads in 188.547 CPU sec, 6.192 real sec
[M::process] read 687988 sequences (100000125 bp) in 1.962 CPU sec, 1.995 real sec...
[M::mem_process_seqs] Processed 688138 reads in 125.376 CPU sec, 4.249 real sec
sorting block 20, #reads = 1074247 mem = 536878691 peak = 904036352
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 280306, 21, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 328, 453)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 975)
[M::mem_pestat] mean and std.dev: (292.95, 154.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1236)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 296, 416)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 864)
[M::mem_pestat] mean and std.dev: (315.21, 153.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1088)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (552, 879, 2583)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6645)
[M::mem_pestat] mean and std.dev: (1350.30, 1005.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8676)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (233, 357, 513)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1073)
[M::mem_pestat] mean and std.dev: (334.47, 184.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1353)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694270 sequences (100000032 bp) in 2.917 CPU sec, 3.411 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 280355, 23, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 299, 499)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1139)
[M::mem_pestat] mean and std.dev: (285.67, 181.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1459)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 293, 413)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 857)
[M::mem_pestat] mean and std.dev: (312.62, 152.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1079)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (380, 478, 1516)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3788)
[M::mem_pestat] mean and std.dev: (909.39, 787.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4924)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 417, 1028)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2698)
[M::mem_pestat] mean and std.dev: (558.87, 453.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3533)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694634 sequences (100000258 bp) in 1.968 CPU sec, 1.996 real sec...
[M::mem_process_seqs] Processed 687804 reads in 195.944 CPU sec, 6.540 real sec
[M::mem_process_seqs] Processed 687988 reads in 129.174 CPU sec, 4.184 real sec
sorting block 21, #reads = 1073818 mem = 536880423 peak = 904036352
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 282627, 21, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 286, 910)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2368)
[M::mem_pestat] mean and std.dev: (298.16, 211.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3097)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 271, 388)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 814)
[M::mem_pestat] mean and std.dev: (293.06, 147.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1027)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 504, 1695)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4667)
[M::mem_pestat] mean and std.dev: (554.78, 555.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6153)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 347, 490)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1040)
[M::mem_pestat] mean and std.dev: (345.40, 191.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1315)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 693912 sequences (100000075 bp) in 2.941 CPU sec, 3.237 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 282286, 15, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 327, 697)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1685)
[M::mem_pestat] mean and std.dev: (372.60, 249.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2179)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 270, 390)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 822)
[M::mem_pestat] mean and std.dev: (293.40, 148.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1038)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (387, 821, 927)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2007)
[M::mem_pestat] mean and std.dev: (537.42, 338.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2547)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 265, 431)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 923)
[M::mem_pestat] mean and std.dev: (304.10, 158.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1169)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 693222 sequences (100000223 bp) in 1.887 CPU sec, 2.078 real sec...
[M::mem_process_seqs] Processed 694270 reads in 194.239 CPU sec, 6.275 real sec
[M::mem_process_seqs] Processed 694634 reads in 131.839 CPU sec, 4.262 real sec
sorting block 22, #reads = 1072328 mem = 536878359 peak = 904036352
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 282850, 20, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 250, 624)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1528)
[M::mem_pestat] mean and std.dev: (362.02, 313.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1980)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 273, 395)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 833)
[M::mem_pestat] mean and std.dev: (297.01, 150.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1052)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (456, 745, 3030)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8178)
[M::mem_pestat] mean and std.dev: (1197.28, 1416.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10752)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 290, 447)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 901)
[M::mem_pestat] mean and std.dev: (300.76, 136.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1128)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 692862 sequences (100000002 bp) in 2.849 CPU sec, 3.353 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 282405, 22, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 422, 1166)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3068)
[M::mem_pestat] mean and std.dev: (603.92, 547.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4019)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 276, 399)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 841)
[M::mem_pestat] mean and std.dev: (299.75, 151.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1062)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (849, 1008, 1430)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2592)
[M::mem_pestat] mean and std.dev: (902.00, 356.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3173)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 329, 1003)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2651)
[M::mem_pestat] mean and std.dev: (488.16, 460.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3475)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 693912 reads in 189.184 CPU sec, 6.332 real sec
[M::process] read 692296 sequences (100000209 bp) in 2.015 CPU sec, 2.025 real sec...
sorting block 23, #reads = 1077177 mem = 536880034 peak = 904036352
[M::mem_process_seqs] Processed 693222 reads in 129.162 CPU sec, 4.358 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 282082, 21, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 250, 494)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1130)
[M::mem_pestat] mean and std.dev: (317.41, 201.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1448)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 278, 402)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 848)
[M::mem_pestat] mean and std.dev: (301.81, 152.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1071)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (254, 776, 961)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2375)
[M::mem_pestat] mean and std.dev: (706.81, 472.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3082)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (235, 333, 578)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1264)
[M::mem_pestat] mean and std.dev: (392.91, 282.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1607)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 24, #reads = 1078216 mem = 536878556 peak = 904036352
[M::process] read 691602 sequences (100000069 bp) in 2.901 CPU sec, 3.193 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 281670, 17, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 298, 639)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1581)
[M::mem_pestat] mean and std.dev: (315.83, 266.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2052)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 279, 401)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 843)
[M::mem_pestat] mean and std.dev: (302.07, 151.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1064)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (103, 304, 601)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1597)
[M::mem_pestat] mean and std.dev: (375.88, 388.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2095)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 314, 1102)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2882)
[M::mem_pestat] mean and std.dev: (436.02, 451.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3772)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 691386 sequences (100000106 bp) in 1.891 CPU sec, 1.999 real sec...
[M::mem_process_seqs] Processed 692862 reads in 197.744 CPU sec, 6.612 real sec
[M::mem_process_seqs] Processed 692296 reads in 134.947 CPU sec, 4.335 real sec
sorting block 25, #reads = 1076935 mem = 536878988 peak = 904036352
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 282004, 15, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 233, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 619)
[M::mem_pestat] mean and std.dev: (243.22, 84.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 764)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 283, 406)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 854)
[M::mem_pestat] mean and std.dev: (305.50, 153.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1078)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (379, 408, 641)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1165)
[M::mem_pestat] mean and std.dev: (440.86, 255.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1462)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (248, 355, 855)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2069)
[M::mem_pestat] mean and std.dev: (480.74, 355.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2676)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 691392 sequences (100000222 bp) in 2.837 CPU sec, 3.188 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 281796, 16, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 198, 1966)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5542)
[M::mem_pestat] mean and std.dev: (836.50, 1056.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7330)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 284, 407)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 855)
[M::mem_pestat] mean and std.dev: (306.12, 153.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1079)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (366, 541, 1095)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2553)
[M::mem_pestat] mean and std.dev: (652.81, 341.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3282)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 250, 573)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1355)
[M::mem_pestat] mean and std.dev: (388.89, 329.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1746)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 691602 reads in 192.772 CPU sec, 6.268 real sec
[M::process] read 690926 sequences (100000206 bp) in 1.972 CPU sec, 1.979 real sec...
[M::mem_process_seqs] Processed 691386 reads in 130.195 CPU sec, 4.219 real sec
sorting block 26, #reads = 1077106 mem = 536878172 peak = 904036352
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 281890, 15, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 276, 511)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1201)
[M::mem_pestat] mean and std.dev: (323.02, 210.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1546)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 285, 409)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 861)
[M::mem_pestat] mean and std.dev: (307.18, 154.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1087)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1261, 1413, 2727)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5659)
[M::mem_pestat] mean and std.dev: (1820.00, 1130.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7125)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 330, 462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 990)
[M::mem_pestat] mean and std.dev: (321.55, 128.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1254)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 690510 sequences (100000175 bp) in 3.060 CPU sec, 3.383 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 281340, 14, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 396, 1101)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2923)
[M::mem_pestat] mean and std.dev: (705.68, 727.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3834)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 286, 410)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 862)
[M::mem_pestat] mean and std.dev: (308.14, 154.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1088)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (434, 1147, 9722)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 28298)
[M::mem_pestat] mean and std.dev: (4086.43, 4287.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 37586)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 220, 452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1020)
[M::mem_pestat] mean and std.dev: (271.75, 154.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1304)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 691392 reads in 194.551 CPU sec, 6.426 real sec
[M::process] read 690590 sequences (100000279 bp) in 1.899 CPU sec, 1.996 real sec...
sorting block 27, #reads = 1077385 mem = 536881054 peak = 904036352
[M::mem_process_seqs] Processed 690926 reads in 130.366 CPU sec, 4.251 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 281591, 27, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 209, 487)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1143)
[M::mem_pestat] mean and std.dev: (295.98, 220.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1471)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 288, 412)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 866)
[M::mem_pestat] mean and std.dev: (309.80, 154.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1093)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (490, 746, 1532)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3616)
[M::mem_pestat] mean and std.dev: (942.23, 888.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4658)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 327, 583)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1333)
[M::mem_pestat] mean and std.dev: (364.12, 250.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1708)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 28, #reads = 1074966 mem = 536882484 peak = 951201792
[M::process] read 689928 sequences (100000165 bp) in 2.766 CPU sec, 3.173 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 281040, 13, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (141, 242, 316)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 666)
[M::mem_pestat] mean and std.dev: (216.18, 102.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 841)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 288, 412)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 866)
[M::mem_pestat] mean and std.dev: (310.20, 155.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1093)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (317, 471, 1623)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4235)
[M::mem_pestat] mean and std.dev: (902.62, 760.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5541)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 343, 415)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 851)
[M::mem_pestat] mean and std.dev: (307.30, 106.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1069)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 690510 reads in 191.131 CPU sec, 6.245 real sec
[M::process] read 690076 sequences (100000014 bp) in 2.059 CPU sec, 2.232 real sec...
[M::mem_process_seqs] Processed 690590 reads in 130.918 CPU sec, 4.521 real sec
sorting block 29, #reads = 1075524 mem = 536880371 peak = 951201792
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 280635, 16, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 265, 713)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1811)
[M::mem_pestat] mean and std.dev: (342.59, 319.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2360)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 289, 414)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 870)
[M::mem_pestat] mean and std.dev: (311.16, 155.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1098)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (604, 1302, 3577)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9523)
[M::mem_pestat] mean and std.dev: (2282.06, 2551.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12496)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 334, 572)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1290)
[M::mem_pestat] mean and std.dev: (317.62, 148.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1649)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 690188 sequences (100000180 bp) in 2.698 CPU sec, 3.157 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 281182, 18, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (250, 353, 683)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1549)
[M::mem_pestat] mean and std.dev: (504.96, 452.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2315)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 288, 414)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 870)
[M::mem_pestat] mean and std.dev: (311.21, 155.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1098)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 573, 1410)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3788)
[M::mem_pestat] mean and std.dev: (713.56, 690.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4977)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 283, 1006)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2660)
[M::mem_pestat] mean and std.dev: (563.07, 601.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3487)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 690178 sequences (100000210 bp) in 1.779 CPU sec, 1.824 real sec...
[M::mem_process_seqs] Processed 689928 reads in 199.913 CPU sec, 6.882 real sec
[M::mem_process_seqs] Processed 690076 reads in 134.451 CPU sec, 4.445 real sec
sorting block 30, #reads = 1075472 mem = 536879344 peak = 951201792
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 281811, 21, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 221, 385)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 799)
[M::mem_pestat] mean and std.dev: (235.43, 112.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1006)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 288, 413)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 869)
[M::mem_pestat] mean and std.dev: (310.77, 155.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1097)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (397, 631, 1058)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2380)
[M::mem_pestat] mean and std.dev: (716.75, 389.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3041)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 334, 652)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1506)
[M::mem_pestat] mean and std.dev: (371.56, 241.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1933)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 690554 sequences (100000140 bp) in 2.666 CPU sec, 3.006 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 281543, 24, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 350, 841)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2181)
[M::mem_pestat] mean and std.dev: (430.42, 411.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2851)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 286, 411)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 863)
[M::mem_pestat] mean and std.dev: (309.31, 154.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1089)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (455, 1360, 1360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3170)
[M::mem_pestat] mean and std.dev: (955.26, 598.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4075)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 379, 1013)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2639)
[M::mem_pestat] mean and std.dev: (627.56, 602.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3452)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 690188 reads in 193.837 CPU sec, 6.288 real sec
[M::process] read 690604 sequences (100000244 bp) in 2.082 CPU sec, 2.135 real sec...
[M::mem_process_seqs] Processed 690178 reads in 133.565 CPU sec, 4.292 real sec
sorting block 31, #reads = 1075018 mem = 536883031 peak = 951201792
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 281431, 13, 81)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (245, 303, 529)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1097)
[M::mem_pestat] mean and std.dev: (314.30, 173.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1381)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 283, 405)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 849)
[M::mem_pestat] mean and std.dev: (305.73, 152.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1071)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 529, 852)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2120)
[M::mem_pestat] mean and std.dev: (495.85, 276.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2754)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 414, 1392)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3738)
[M::mem_pestat] mean and std.dev: (766.88, 829.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4911)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 690762 sequences (100000195 bp) in 2.752 CPU sec, 3.140 real sec...
sorting block 32, #reads = 1073959 mem = 536877071 peak = 951201792
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 281428, 32, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 389, 993)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2569)
[M::mem_pestat] mean and std.dev: (553.84, 571.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3357)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 283, 407)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 853)
[M::mem_pestat] mean and std.dev: (306.47, 153.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1076)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (512, 736, 972)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1892)
[M::mem_pestat] mean and std.dev: (697.13, 455.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2519)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (259, 362, 856)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2050)
[M::mem_pestat] mean and std.dev: (409.44, 298.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2647)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 690740 sequences (100000067 bp) in 1.715 CPU sec, 1.726 real sec...
[M::mem_process_seqs] Processed 690554 reads in 189.845 CPU sec, 6.157 real sec
[M::mem_process_seqs] Processed 690604 reads in 130.503 CPU sec, 4.444 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 281377, 19, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 224, 283)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 521)
[M::mem_pestat] mean and std.dev: (206.71, 60.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 640)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 283, 406)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 852)
[M::mem_pestat] mean and std.dev: (306.44, 153.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1075)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (307, 551, 2212)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6022)
[M::mem_pestat] mean and std.dev: (1044.74, 960.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7927)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 297, 449)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1007)
[M::mem_pestat] mean and std.dev: (318.52, 185.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1286)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 33, #reads = 1075078 mem = 536879746 peak = 951201792
[M::process] read 690796 sequences (100000020 bp) in 2.735 CPU sec, 3.079 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 281543, 23, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 409, 1084)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2850)
[M::mem_pestat] mean and std.dev: (514.58, 501.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3733)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 282, 406)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 852)
[M::mem_pestat] mean and std.dev: (305.83, 153.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1075)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (563, 1441, 2689)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6941)
[M::mem_pestat] mean and std.dev: (1748.39, 1628.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9067)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 301, 615)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1435)
[M::mem_pestat] mean and std.dev: (387.15, 290.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1845)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 690642 sequences (100000087 bp) in 2.172 CPU sec, 2.241 real sec...
[M::mem_process_seqs] Processed 690762 reads in 202.813 CPU sec, 6.762 real sec
[M::mem_process_seqs] Processed 690740 reads in 135.821 CPU sec, 4.351 real sec
sorting block 34, #reads = 1074879 mem = 536877258 peak = 951201792
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 281141, 9, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 283, 987)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2553)
[M::mem_pestat] mean and std.dev: (515.78, 483.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3336)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 282, 405)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 849)
[M::mem_pestat] mean and std.dev: (305.40, 152.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1071)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 397, 746)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1780)
[M::mem_pestat] mean and std.dev: (476.17, 325.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2297)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 689996 sequences (100000128 bp) in 2.702 CPU sec, 3.145 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 281144, 10, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 262, 437)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 981)
[M::mem_pestat] mean and std.dev: (268.77, 170.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1253)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 283, 405)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 849)
[M::mem_pestat] mean and std.dev: (305.53, 152.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1071)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (446, 1411, 2118)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5462)
[M::mem_pestat] mean and std.dev: (938.50, 657.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7134)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 295, 676)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1618)
[M::mem_pestat] mean and std.dev: (438.98, 345.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2089)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 689904 sequences (100000004 bp) in 1.973 CPU sec, 2.078 real sec...
[M::mem_process_seqs] Processed 690796 reads in 202.006 CPU sec, 6.563 real sec
[M::mem_process_seqs] Processed 690642 reads in 136.321 CPU sec, 4.426 real sec
sorting block 35, #reads = 1075150 mem = 536879923 peak = 951201792
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 281050, 16, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 379, 961)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2499)
[M::mem_pestat] mean and std.dev: (480.02, 474.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3268)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 285, 407)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 851)
[M::mem_pestat] mean and std.dev: (307.07, 152.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1073)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (399, 838, 2836)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7710)
[M::mem_pestat] mean and std.dev: (1333.50, 1127.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10147)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 335, 405)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 763)
[M::mem_pestat] mean and std.dev: (295.87, 96.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 942)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 690038 sequences (100000015 bp) in 2.715 CPU sec, 3.126 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 280974, 6, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 240, 524)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1204)
[M::mem_pestat] mean and std.dev: (296.55, 182.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1544)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 285, 406)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 848)
[M::mem_pestat] mean and std.dev: (307.05, 152.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1069)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 260, 726)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1746)
[M::mem_pestat] mean and std.dev: (479.24, 513.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2535)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 689752 sequences (100000208 bp) in 2.029 CPU sec, 2.060 real sec...
[M::mem_process_seqs] Processed 689996 reads in 206.532 CPU sec, 6.742 real sec
sorting block 36, #reads = 1074959 mem = 536879193 peak = 951201792
[M::mem_process_seqs] Processed 689904 reads in 141.906 CPU sec, 4.551 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 281066, 19, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 391, 643)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1583)
[M::mem_pestat] mean and std.dev: (405.60, 312.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2053)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 283, 404)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 844)
[M::mem_pestat] mean and std.dev: (305.40, 151.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1064)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 643, 1290)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3486)
[M::mem_pestat] mean and std.dev: (884.67, 995.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4865)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 373, 514)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1118)
[M::mem_pestat] mean and std.dev: (331.87, 187.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1420)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 37, #reads = 1074056 mem = 536876683 peak = 976363520
[M::process] read 689856 sequences (100000231 bp) in 2.884 CPU sec, 3.331 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 281044, 21, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 235, 319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 645)
[M::mem_pestat] mean and std.dev: (227.30, 87.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 808)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 285, 407)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 849)
[M::mem_pestat] mean and std.dev: (307.23, 152.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1070)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (652, 1039, 1250)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2446)
[M::mem_pestat] mean and std.dev: (904.25, 482.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3044)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (239, 336, 559)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1199)
[M::mem_pestat] mean and std.dev: (309.53, 136.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1519)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 689524 sequences (100000051 bp) in 2.071 CPU sec, 2.086 real sec...
[M::mem_process_seqs] Processed 690038 reads in 197.536 CPU sec, 6.350 real sec
[M::mem_process_seqs] Processed 689752 reads in 135.652 CPU sec, 4.327 real sec
sorting block 38, #reads = 1073513 mem = 536878725 peak = 976363520
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 281288, 24, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 284, 463)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1055)
[M::mem_pestat] mean and std.dev: (307.07, 162.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1351)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 287, 411)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 863)
[M::mem_pestat] mean and std.dev: (309.59, 154.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1089)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (475, 611, 2139)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5467)
[M::mem_pestat] mean and std.dev: (1168.67, 1209.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7131)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (252, 412, 1016)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2544)
[M::mem_pestat] mean and std.dev: (485.67, 335.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3308)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 689490 sequences (100000207 bp) in 2.829 CPU sec, 3.152 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 281212, 17, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 291, 397)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 807)
[M::mem_pestat] mean and std.dev: (276.00, 121.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1012)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 287, 409)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 855)
[M::mem_pestat] mean and std.dev: (308.87, 153.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1078)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 921, 1629)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4453)
[M::mem_pestat] mean and std.dev: (880.56, 722.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5865)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (232, 368, 519)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1093)
[M::mem_pestat] mean and std.dev: (364.19, 163.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1380)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 689596 sequences (100000063 bp) in 2.179 CPU sec, 2.186 real sec...
[M::mem_process_seqs] Processed 689856 reads in 202.779 CPU sec, 6.752 real sec
[M::mem_process_seqs] Processed 689524 reads in 138.320 CPU sec, 4.487 real sec
sorting block 39, #reads = 1074498 mem = 536876782 peak = 976363520
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 280726, 12, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 322, 840)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2096)
[M::mem_pestat] mean and std.dev: (393.50, 318.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2724)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 287, 411)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 859)
[M::mem_pestat] mean and std.dev: (310.14, 154.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1083)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (343, 1085, 1513)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3853)
[M::mem_pestat] mean and std.dev: (1028.25, 853.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5023)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (274, 377, 757)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1723)
[M::mem_pestat] mean and std.dev: (476.23, 310.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2206)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 689116 sequences (100000224 bp) in 3.157 CPU sec, 3.613 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 280829, 28, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (146, 287, 576)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1436)
[M::mem_pestat] mean and std.dev: (272.28, 159.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1866)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 287, 406)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 844)
[M::mem_pestat] mean and std.dev: (307.68, 151.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1063)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (553, 1633, 2458)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6268)
[M::mem_pestat] mean and std.dev: (1525.56, 1143.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8173)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 398, 825)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2023)
[M::mem_pestat] mean and std.dev: (459.75, 380.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2622)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 689490 reads in 198.919 CPU sec, 6.553 real sec
[M::process] read 688682 sequences (100000204 bp) in 1.932 CPU sec, 2.017 real sec...
[M::mem_process_seqs] Processed 689596 reads in 140.541 CPU sec, 4.530 real sec
sorting block 40, #reads = 1074306 mem = 536876890 peak = 976363520
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 281235, 24, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 320, 1430)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3858)
[M::mem_pestat] mean and std.dev: (798.84, 917.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5072)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 289, 409)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 851)
[M::mem_pestat] mean and std.dev: (309.53, 152.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1072)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (749, 1458, 1507)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3023)
[M::mem_pestat] mean and std.dev: (1075.59, 702.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3887)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (271, 408, 1043)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2587)
[M::mem_pestat] mean and std.dev: (682.04, 714.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3542)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 41, #reads = 1074915 mem = 536877041 peak = 976363520
[M::process] read 688594 sequences (100000163 bp) in 3.111 CPU sec, 3.609 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 280576, 13, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 254, 422)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 944)
[M::mem_pestat] mean and std.dev: (290.94, 160.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1205)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 289, 410)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 852)
[M::mem_pestat] mean and std.dev: (310.26, 152.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1073)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (674, 1068, 4174)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 11174)
[M::mem_pestat] mean and std.dev: (1853.38, 1592.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14674)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 325, 999)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2641)
[M::mem_pestat] mean and std.dev: (644.19, 686.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3462)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 689116 reads in 197.055 CPU sec, 6.380 real sec
[M::process] read 688630 sequences (100000140 bp) in 2.131 CPU sec, 2.471 real sec...
[M::mem_process_seqs] Processed 688682 reads in 132.039 CPU sec, 4.377 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (77, 280825, 15, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 293, 561)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1321)
[M::mem_pestat] mean and std.dev: (398.84, 283.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1701)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 291, 411)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 855)
[M::mem_pestat] mean and std.dev: (311.46, 153.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1077)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (671, 893, 1174)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2180)
[M::mem_pestat] mean and std.dev: (973.27, 452.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2782)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (235, 353, 1136)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2938)
[M::mem_pestat] mean and std.dev: (731.49, 850.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4132)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 42, #reads = 1073286 mem = 536882519 peak = 976363520
[M::process] read 688346 sequences (100000080 bp) in 2.869 CPU sec, 3.354 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 281122, 16, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (137, 196, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 746)
[M::mem_pestat] mean and std.dev: (213.80, 122.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 949)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 293, 415)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 865)
[M::mem_pestat] mean and std.dev: (313.58, 154.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1090)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (739, 1162, 2229)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5209)
[M::mem_pestat] mean and std.dev: (1534.20, 1289.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6699)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 335, 532)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1174)
[M::mem_pestat] mean and std.dev: (358.79, 260.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1495)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 688594 reads in 192.470 CPU sec, 6.352 real sec
[M::process] read 694788 sequences (100000291 bp) in 1.852 CPU sec, 1.876 real sec...
[M::mem_process_seqs] Processed 688630 reads in 132.340 CPU sec, 4.286 real sec
sorting block 43, #reads = 1074710 mem = 536879796 peak = 976363520
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 281007, 31, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (236, 348, 995)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2513)
[M::mem_pestat] mean and std.dev: (524.10, 445.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3272)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 295, 418)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 874)
[M::mem_pestat] mean and std.dev: (315.45, 156.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1102)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (396, 703, 1290)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3078)
[M::mem_pestat] mean and std.dev: (752.07, 474.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3972)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (252, 407, 839)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2013)
[M::mem_pestat] mean and std.dev: (402.10, 328.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2600)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694804 sequences (100000223 bp) in 2.969 CPU sec, 3.466 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 282421, 22, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (236, 289, 936)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2336)
[M::mem_pestat] mean and std.dev: (466.85, 406.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3036)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 268, 388)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 816)
[M::mem_pestat] mean and std.dev: (292.24, 147.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1030)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (703, 1787, 4574)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12316)
[M::mem_pestat] mean and std.dev: (2867.50, 2705.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 16187)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 244, 512)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1204)
[M::mem_pestat] mean and std.dev: (342.27, 256.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1550)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 688346 reads in 199.160 CPU sec, 6.454 real sec
[M::process] read 693836 sequences (100000049 bp) in 2.075 CPU sec, 2.221 real sec...
[M::mem_process_seqs] Processed 694788 reads in 143.288 CPU sec, 4.615 real sec
sorting block 44, #reads = 1073536 mem = 536879226 peak = 976363520
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 282509, 21, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 242, 503)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1069)
[M::mem_pestat] mean and std.dev: (284.63, 131.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1352)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 269, 388)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 816)
[M::mem_pestat] mean and std.dev: (292.10, 147.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1030)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (619, 1507, 3810)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10192)
[M::mem_pestat] mean and std.dev: (2229.29, 1811.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13383)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 315, 1437)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3991)
[M::mem_pestat] mean and std.dev: (695.49, 782.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5268)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 693318 sequences (100000115 bp) in 2.899 CPU sec, 3.156 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 281958, 16, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (251, 375, 780)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1838)
[M::mem_pestat] mean and std.dev: (452.58, 342.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2367)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 272, 390)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 818)
[M::mem_pestat] mean and std.dev: (294.28, 147.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1032)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (267, 702, 982)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2412)
[M::mem_pestat] mean and std.dev: (583.21, 421.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3127)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 338, 556)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1302)
[M::mem_pestat] mean and std.dev: (375.79, 298.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1675)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 692638 sequences (100000183 bp) in 1.729 CPU sec, 1.771 real sec...
[M::mem_process_seqs] Processed 694804 reads in 197.692 CPU sec, 6.364 real sec
sorting block 45, #reads = 1074706 mem = 536879421 peak = 976363520
[M::mem_process_seqs] Processed 693836 reads in 142.032 CPU sec, 4.561 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 282550, 26, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (146, 206, 291)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 581)
[M::mem_pestat] mean and std.dev: (188.27, 58.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 726)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 274, 392)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 820)
[M::mem_pestat] mean and std.dev: (295.72, 147.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1034)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1366, 1799, 1918)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (262, 3022)
[M::mem_pestat] mean and std.dev: (1586.27, 487.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3574)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (231, 311, 527)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1119)
[M::mem_pestat] mean and std.dev: (320.44, 156.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1415)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 46, #reads = 1077057 mem = 536881146 peak = 996188160
[M::process] read 692192 sequences (100000036 bp) in 2.717 CPU sec, 3.197 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 282350, 16, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 260, 465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 985)
[M::mem_pestat] mean and std.dev: (326.44, 178.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1245)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 277, 397)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 833)
[M::mem_pestat] mean and std.dev: (299.09, 149.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1051)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (237, 970, 2245)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6261)
[M::mem_pestat] mean and std.dev: (1065.07, 847.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8269)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (278, 504, 1720)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4604)
[M::mem_pestat] mean and std.dev: (807.06, 871.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6046)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 691716 sequences (100000077 bp) in 2.085 CPU sec, 2.127 real sec...
[M::mem_process_seqs] Processed 693318 reads in 197.037 CPU sec, 6.345 real sec
[M::mem_process_seqs] Processed 692638 reads in 143.575 CPU sec, 4.609 real sec
sorting block 47, #reads = 1076196 mem = 536876949 peak = 996188160
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 282051, 30, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 268, 676)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1636)
[M::mem_pestat] mean and std.dev: (440.37, 383.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2116)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 279, 399)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 835)
[M::mem_pestat] mean and std.dev: (300.70, 149.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1053)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (665, 665, 1195)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2255)
[M::mem_pestat] mean and std.dev: (676.08, 412.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2785)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 249, 529)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1229)
[M::mem_pestat] mean and std.dev: (315.17, 201.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1579)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 691580 sequences (100000067 bp) in 2.987 CPU sec, 3.343 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 281594, 27, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 212, 426)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 928)
[M::mem_pestat] mean and std.dev: (243.21, 118.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1179)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 281, 400)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 836)
[M::mem_pestat] mean and std.dev: (301.61, 149.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1054)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (308, 1234, 1965)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5279)
[M::mem_pestat] mean and std.dev: (1211.46, 1092.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6936)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 269, 770)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1974)
[M::mem_pestat] mean and std.dev: (406.36, 339.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2576)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 690780 sequences (100000004 bp) in 1.920 CPU sec, 1.928 real sec...
[M::mem_process_seqs] Processed 692192 reads in 197.382 CPU sec, 6.423 real sec
[M::mem_process_seqs] Processed 691716 reads in 143.646 CPU sec, 4.684 real sec
sorting block 48, #reads = 1076685 mem = 536878309 peak = 996188160
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (77, 281711, 18, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 287, 426)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 952)
[M::mem_pestat] mean and std.dev: (278.37, 134.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1215)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 282, 401)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 837)
[M::mem_pestat] mean and std.dev: (302.49, 148.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1055)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 425, 820)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2050)
[M::mem_pestat] mean and std.dev: (503.39, 332.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2665)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 249, 573)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1265)
[M::mem_pestat] mean and std.dev: (336.69, 247.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1611)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 691002 sequences (100000243 bp) in 2.855 CPU sec, 3.286 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 281472, 24, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (234, 372, 821)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1995)
[M::mem_pestat] mean and std.dev: (517.05, 380.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2582)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 284, 403)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 841)
[M::mem_pestat] mean and std.dev: (304.07, 149.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1060)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (48, 1128, 1889)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5571)
[M::mem_pestat] mean and std.dev: (970.74, 850.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7412)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 262, 528)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1176)
[M::mem_pestat] mean and std.dev: (299.20, 164.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1500)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 690512 sequences (100000154 bp) in 1.950 CPU sec, 1.989 real sec...
[M::mem_process_seqs] Processed 691580 reads in 197.549 CPU sec, 6.360 real sec
sorting block 49, #reads = 1075514 mem = 536877942 peak = 996188160
[M::mem_process_seqs] Processed 690780 reads in 136.328 CPU sec, 4.598 real sec
sorting block 50, #reads = 1074973 mem = 536878115 peak = 996188160
[M::process] read 690142 sequences (100000243 bp) in 2.928 CPU sec, 3.452 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (73, 281480, 25, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 351, 1006)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2570)
[M::mem_pestat] mean and std.dev: (601.86, 608.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3352)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 287, 408)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 854)
[M::mem_pestat] mean and std.dev: (307.44, 151.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1077)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (422, 689, 1232)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2852)
[M::mem_pestat] mean and std.dev: (824.29, 584.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3662)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (237, 317, 950)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2376)
[M::mem_pestat] mean and std.dev: (478.76, 391.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3089)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 689922 sequences (100000123 bp) in 1.832 CPU sec, 1.912 real sec...
[M::mem_process_seqs] Processed 690512 reads in 120.032 CPU sec, 3.853 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 281575, 13, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 310, 471)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1083)
[M::mem_pestat] mean and std.dev: (323.59, 193.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1389)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 286, 405)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 845)
[M::mem_pestat] mean and std.dev: (305.67, 150.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1065)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (396, 1209, 6950)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 20058)
[M::mem_pestat] mean and std.dev: (2870.23, 3077.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 26612)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 352, 772)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1828)
[M::mem_pestat] mean and std.dev: (409.08, 313.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2356)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 281786, 15, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 267, 639)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1517)
[M::mem_pestat] mean and std.dev: (308.60, 205.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1956)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 288, 409)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 855)
[M::mem_pestat] mean and std.dev: (308.32, 152.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1078)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (449, 779, 1631)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3995)
[M::mem_pestat] mean and std.dev: (910.20, 619.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5177)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (271, 353, 552)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1114)
[M::mem_pestat] mean and std.dev: (318.31, 105.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1395)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 691002 reads in 307.565 CPU sec, 10.196 real sec
[M::process] read 689772 sequences (100000290 bp) in 2.338 CPU sec, 2.416 real sec...
[M::mem_process_seqs] Processed 690142 reads in 155.891 CPU sec, 5.038 real sec
sorting block 51, #reads = 1075043 mem = 536880397 peak = 996188160
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 280882, 19, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 454, 1044)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2738)
[M::mem_pestat] mean and std.dev: (517.18, 502.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3585)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 288, 410)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 858)
[M::mem_pestat] mean and std.dev: (309.20, 152.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1082)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (25, 763, 1487)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4411)
[M::mem_pestat] mean and std.dev: (874.72, 954.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5873)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 277, 391)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 773)
[M::mem_pestat] mean and std.dev: (264.72, 102.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 964)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 689780 sequences (100000072 bp) in 2.838 CPU sec, 3.378 real sec...
sorting block 52, #reads = 1074216 mem = 536880404 peak = 996188160
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 280670, 27, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (270, 382, 758)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1734)
[M::mem_pestat] mean and std.dev: (425.39, 296.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2222)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 289, 412)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 862)
[M::mem_pestat] mean and std.dev: (310.28, 153.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1087)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (735, 1999, 6683)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 18579)
[M::mem_pestat] mean and std.dev: (3317.48, 2799.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 24527)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 283, 511)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1111)
[M::mem_pestat] mean and std.dev: (394.42, 307.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1626)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 689922 reads in 195.439 CPU sec, 6.550 real sec
[M::process] read 689698 sequences (100000266 bp) in 2.271 CPU sec, 2.430 real sec...
[M::mem_process_seqs] Processed 689772 reads in 136.504 CPU sec, 4.423 real sec
sorting block 53, #reads = 1074066 mem = 536878279 peak = 996188160
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 281481, 25, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (235, 371, 462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 916)
[M::mem_pestat] mean and std.dev: (348.53, 188.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1143)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 289, 411)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 859)
[M::mem_pestat] mean and std.dev: (309.73, 152.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1083)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (820, 1165, 1744)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3592)
[M::mem_pestat] mean and std.dev: (1076.39, 547.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4516)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 319, 519)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1131)
[M::mem_pestat] mean and std.dev: (338.04, 152.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1437)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 689862 sequences (100000075 bp) in 2.682 CPU sec, 3.298 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 280956, 17, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 269, 947)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2519)
[M::mem_pestat] mean and std.dev: (402.29, 433.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3305)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 288, 412)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 864)
[M::mem_pestat] mean and std.dev: (310.29, 154.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1090)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (354, 596, 3871)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10905)
[M::mem_pestat] mean and std.dev: (1921.12, 2226.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14422)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 291, 606)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1438)
[M::mem_pestat] mean and std.dev: (326.16, 208.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1854)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 690282 sequences (100000169 bp) in 2.083 CPU sec, 2.164 real sec...
[M::mem_process_seqs] Processed 689780 reads in 207.754 CPU sec, 6.880 real sec
[M::mem_process_seqs] Processed 689698 reads in 140.620 CPU sec, 4.534 real sec
sorting block 54, #reads = 1074019 mem = 536878167 peak = 996188160
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 280761, 20, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 355, 1201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3209)
[M::mem_pestat] mean and std.dev: (526.20, 541.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4213)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 286, 409)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 855)
[M::mem_pestat] mean and std.dev: (308.58, 152.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1078)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (548, 781, 1303)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2813)
[M::mem_pestat] mean and std.dev: (922.70, 566.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3568)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 254, 891)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2339)
[M::mem_pestat] mean and std.dev: (407.61, 395.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3063)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 690286 sequences (100000292 bp) in 2.637 CPU sec, 3.141 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 281269, 21, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 233, 546)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1280)
[M::mem_pestat] mean and std.dev: (346.29, 250.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1647)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 285, 408)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 854)
[M::mem_pestat] mean and std.dev: (307.76, 152.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1077)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 651, 1511)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4159)
[M::mem_pestat] mean and std.dev: (690.37, 675.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5483)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 293, 681)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1643)
[M::mem_pestat] mean and std.dev: (430.42, 361.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2124)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 690264 sequences (100000160 bp) in 1.950 CPU sec, 1.965 real sec...
[M::mem_process_seqs] Processed 689862 reads in 208.257 CPU sec, 6.729 real sec
[M::mem_process_seqs] Processed 690282 reads in 141.118 CPU sec, 4.591 real sec
sorting block 55, #reads = 1073861 mem = 536880863 peak = 996188160
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 281336, 18, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 314, 488)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1092)
[M::mem_pestat] mean and std.dev: (332.04, 199.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1394)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 284, 406)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 850)
[M::mem_pestat] mean and std.dev: (306.05, 151.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1072)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (716, 2764, 3684)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9620)
[M::mem_pestat] mean and std.dev: (2148.28, 1502.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12588)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (238, 318, 495)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1009)
[M::mem_pestat] mean and std.dev: (346.16, 181.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1266)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 690156 sequences (100000035 bp) in 2.615 CPU sec, 2.984 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 280457, 23, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 279, 454)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1014)
[M::mem_pestat] mean and std.dev: (279.38, 177.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1294)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 284, 407)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 851)
[M::mem_pestat] mean and std.dev: (306.90, 152.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1073)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (373, 887, 961)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2137)
[M::mem_pestat] mean and std.dev: (742.05, 462.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2725)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 286, 579)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1379)
[M::mem_pestat] mean and std.dev: (289.75, 173.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1779)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 690048 sequences (100000187 bp) in 2.078 CPU sec, 2.087 real sec...
[M::mem_process_seqs] Processed 690286 reads in 202.752 CPU sec, 6.602 real sec
sorting block 56, #reads = 1074254 mem = 536880452 peak = 996188160
[M::mem_process_seqs] Processed 690264 reads in 137.628 CPU sec, 4.396 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 281082, 34, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 352, 486)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1102)
[M::mem_pestat] mean and std.dev: (334.65, 195.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1410)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 284, 406)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 848)
[M::mem_pestat] mean and std.dev: (306.69, 152.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1069)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 695, 1870)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5292)
[M::mem_pestat] mean and std.dev: (867.23, 1084.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7003)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 361, 1000)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2640)
[M::mem_pestat] mean and std.dev: (494.05, 483.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3460)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 57, #reads = 1074019 mem = 536879778 peak = 1042575360
[M::process] read 689870 sequences (100000194 bp) in 2.547 CPU sec, 3.257 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 280841, 37, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 395, 880)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2242)
[M::mem_pestat] mean and std.dev: (549.28, 417.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2923)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 284, 406)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 848)
[M::mem_pestat] mean and std.dev: (306.10, 152.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1069)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (246, 762, 1055)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2673)
[M::mem_pestat] mean and std.dev: (718.71, 629.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3482)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 293, 518)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1144)
[M::mem_pestat] mean and std.dev: (285.52, 153.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1457)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 689824 sequences (100000255 bp) in 1.991 CPU sec, 2.056 real sec...
[M::mem_process_seqs] Processed 690156 reads in 203.154 CPU sec, 6.684 real sec
[M::mem_process_seqs] Processed 690048 reads in 138.658 CPU sec, 4.496 real sec
sorting block 58, #reads = 1075274 mem = 536880200 peak = 1042575360
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 280959, 18, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 253, 473)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1071)
[M::mem_pestat] mean and std.dev: (219.04, 94.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1370)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 283, 405)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 845)
[M::mem_pestat] mean and std.dev: (305.81, 151.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1065)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (705, 833, 3406)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8808)
[M::mem_pestat] mean and std.dev: (1993.22, 1994.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11509)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 275, 393)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 757)
[M::mem_pestat] mean and std.dev: (278.12, 111.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 939)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 689704 sequences (100000037 bp) in 2.759 CPU sec, 3.273 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (80, 281195, 12, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 224, 385)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 779)
[M::mem_pestat] mean and std.dev: (259.35, 122.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 976)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 286, 407)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 849)
[M::mem_pestat] mean and std.dev: (307.55, 152.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1070)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (585, 1589, 2673)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6849)
[M::mem_pestat] mean and std.dev: (1461.75, 1064.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8937)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 439, 668)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1578)
[M::mem_pestat] mean and std.dev: (393.21, 248.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2033)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 689870 reads in 195.299 CPU sec, 6.338 real sec
[M::process] read 689654 sequences (100000210 bp) in 2.140 CPU sec, 2.153 real sec...
[M::mem_process_seqs] Processed 689824 reads in 141.572 CPU sec, 4.593 real sec
sorting block 59, #reads = 1073910 mem = 536881932 peak = 1042575360
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 281357, 9, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 286, 892)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2346)
[M::mem_pestat] mean and std.dev: (391.10, 371.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3073)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 285, 409)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 855)
[M::mem_pestat] mean and std.dev: (307.98, 152.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1078)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 304, 1111)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2951)
[M::mem_pestat] mean and std.dev: (503.35, 474.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3871)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 689444 sequences (100000205 bp) in 2.779 CPU sec, 3.166 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 281275, 26, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 272, 373)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 727)
[M::mem_pestat] mean and std.dev: (267.34, 99.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 904)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 287, 409)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 855)
[M::mem_pestat] mean and std.dev: (308.77, 153.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1078)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (322, 610, 2212)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5992)
[M::mem_pestat] mean and std.dev: (1156.08, 1472.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7882)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 340, 683)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1653)
[M::mem_pestat] mean and std.dev: (390.68, 311.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2138)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 689650 sequences (100000216 bp) in 2.009 CPU sec, 2.051 real sec...
[M::mem_process_seqs] Processed 689704 reads in 197.237 CPU sec, 6.352 real sec
sorting block 60, #reads = 1073960 mem = 536881550 peak = 1042575360
[M::mem_process_seqs] Processed 689654 reads in 132.797 CPU sec, 4.269 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 281121, 9, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 272, 1038)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2742)
[M::mem_pestat] mean and std.dev: (634.28, 622.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3594)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 286, 409)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 853)
[M::mem_pestat] mean and std.dev: (308.71, 153.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1075)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 279, 431)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 863)
[M::mem_pestat] mean and std.dev: (315.44, 164.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1079)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 61, #reads = 1074286 mem = 536878533 peak = 1042575360
[M::process] read 689490 sequences (100000083 bp) in 3.002 CPU sec, 3.463 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 280878, 13, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 323, 492)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1036)
[M::mem_pestat] mean and std.dev: (305.31, 146.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1308)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 286, 408)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 852)
[M::mem_pestat] mean and std.dev: (308.42, 153.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1074)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (569, 1276, 3177)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8393)
[M::mem_pestat] mean and std.dev: (1761.15, 1668.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11001)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (263, 357, 731)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1667)
[M::mem_pestat] mean and std.dev: (514.22, 411.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2159)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 689096 sequences (100000284 bp) in 1.973 CPU sec, 2.004 real sec...
[M::mem_process_seqs] Processed 689444 reads in 202.623 CPU sec, 6.528 real sec
[M::mem_process_seqs] Processed 689650 reads in 133.776 CPU sec, 4.268 real sec
sorting block 62, #reads = 1074361 mem = 536885113 peak = 1042575360
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 280988, 27, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (233, 460, 622)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1400)
[M::mem_pestat] mean and std.dev: (442.19, 288.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1789)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 289, 411)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 859)
[M::mem_pestat] mean and std.dev: (309.96, 153.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1083)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (454, 579, 1005)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2107)
[M::mem_pestat] mean and std.dev: (695.96, 383.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2658)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 332, 660)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1554)
[M::mem_pestat] mean and std.dev: (421.56, 299.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2001)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 688858 sequences (100000033 bp) in 2.718 CPU sec, 3.069 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 280557, 21, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 285, 617)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1461)
[M::mem_pestat] mean and std.dev: (363.54, 231.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1883)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 291, 413)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 863)
[M::mem_pestat] mean and std.dev: (312.07, 154.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1088)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (82, 434, 1435)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4141)
[M::mem_pestat] mean and std.dev: (942.62, 1128.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5494)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 290, 462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 898)
[M::mem_pestat] mean and std.dev: (288.15, 115.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1116)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 688550 sequences (100000197 bp) in 2.006 CPU sec, 2.043 real sec...
[M::mem_process_seqs] Processed 689490 reads in 202.591 CPU sec, 6.548 real sec
[M::mem_process_seqs] Processed 689096 reads in 134.423 CPU sec, 4.305 real sec
sorting block 63, #reads = 1073863 mem = 536878174 peak = 1042575360
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 280411, 24, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 521, 1300)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3462)
[M::mem_pestat] mean and std.dev: (839.41, 878.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4543)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 290, 412)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 860)
[M::mem_pestat] mean and std.dev: (311.64, 154.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1084)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (52, 296, 569)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1603)
[M::mem_pestat] mean and std.dev: (258.52, 281.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2120)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (282, 311, 610)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1266)
[M::mem_pestat] mean and std.dev: (441.28, 283.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1594)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 687930 sequences (100000098 bp) in 2.854 CPU sec, 3.154 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 280580, 8, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 322, 553)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1307)
[M::mem_pestat] mean and std.dev: (379.28, 301.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1684)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 292, 415)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 867)
[M::mem_pestat] mean and std.dev: (313.52, 155.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1093)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 284, 388)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 824)
[M::mem_pestat] mean and std.dev: (284.54, 163.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1042)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 687892 sequences (100000085 bp) in 1.928 CPU sec, 1.979 real sec...
[M::mem_process_seqs] Processed 688858 reads in 197.764 CPU sec, 6.448 real sec
sorting block 64, #reads = 1073799 mem = 536880894 peak = 1042575360
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 280739, 17, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 612, 866)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2150)
[M::mem_pestat] mean and std.dev: (515.60, 360.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2792)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 295, 417)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 869)
[M::mem_pestat] mean and std.dev: (315.09, 154.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1095)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (824, 1290, 1428)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2636)
[M::mem_pestat] mean and std.dev: (1064.31, 613.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3520)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 318, 562)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1294)
[M::mem_pestat] mean and std.dev: (316.81, 171.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1660)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 689390 sequences (100000115 bp) in 2.202 CPU sec, 2.369 real sec...
[M::mem_process_seqs] Processed 687930 reads in 113.322 CPU sec, 3.713 real sec
[M::mem_process_seqs] Processed 688550 reads in 287.544 CPU sec, 9.355 real sec
sorting block 65, #reads = 1074415 mem = 536878934 peak = 1042575360
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 279824, 21, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 543, 1085)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2831)
[M::mem_pestat] mean and std.dev: (680.87, 553.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3704)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 293, 414)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 860)
[M::mem_pestat] mean and std.dev: (313.28, 153.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1083)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (409, 1325, 2131)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5575)
[M::mem_pestat] mean and std.dev: (1475.70, 1371.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7297)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 313, 695)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1711)
[M::mem_pestat] mean and std.dev: (410.35, 357.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2219)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695896 sequences (100000241 bp) in 2.612 CPU sec, 3.346 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 280941, 34, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (146, 288, 428)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 992)
[M::mem_pestat] mean and std.dev: (275.80, 192.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1274)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 289, 410)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 854)
[M::mem_pestat] mean and std.dev: (309.99, 152.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1076)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (368, 897, 1768)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4568)
[M::mem_pestat] mean and std.dev: (997.55, 676.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5968)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 320, 582)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1354)
[M::mem_pestat] mean and std.dev: (394.62, 337.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1744)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 687892 reads in 214.698 CPU sec, 6.922 real sec
[M::process] read 694994 sequences (100000256 bp) in 2.709 CPU sec, 2.899 real sec...
sorting block 66, #reads = 1073191 mem = 536880840 peak = 1042575360
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 282735, 17, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (125, 232, 430)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1040)
[M::mem_pestat] mean and std.dev: (288.83, 207.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1345)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 265, 385)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 811)
[M::mem_pestat] mean and std.dev: (290.13, 148.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1024)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (284, 815, 1499)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3929)
[M::mem_pestat] mean and std.dev: (839.88, 557.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5144)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (237, 419, 664)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1518)
[M::mem_pestat] mean and std.dev: (430.37, 303.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1945)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694154 sequences (100000050 bp) in 2.148 CPU sec, 2.209 real sec...
[M::mem_process_seqs] Processed 695896 reads in 115.701 CPU sec, 3.715 real sec
[M::mem_process_seqs] Processed 689390 reads in 289.350 CPU sec, 9.302 real sec
sorting block 67, #reads = 1076563 mem = 536883479 peak = 1042575360
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 282441, 16, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (228, 314, 544)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1176)
[M::mem_pestat] mean and std.dev: (341.96, 212.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1492)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 268, 391)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 825)
[M::mem_pestat] mean and std.dev: (293.83, 150.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1042)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (396, 819, 2133)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5607)
[M::mem_pestat] mean and std.dev: (1189.00, 1012.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7344)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 321, 524)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1174)
[M::mem_pestat] mean and std.dev: (334.72, 221.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1499)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 693522 sequences (100000114 bp) in 2.961 CPU sec, 3.322 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 282715, 11, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (229, 351, 1621)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4405)
[M::mem_pestat] mean and std.dev: (686.90, 769.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5797)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 271, 395)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 835)
[M::mem_pestat] mean and std.dev: (296.80, 151.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1055)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (79, 580, 1321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3805)
[M::mem_pestat] mean and std.dev: (886.18, 986.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5047)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 273, 407)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 929)
[M::mem_pestat] mean and std.dev: (258.47, 155.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1190)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 694994 reads in 217.337 CPU sec, 7.061 real sec
[M::mem_process_seqs] Processed 694154 reads in 134.839 CPU sec, 4.380 real sec
[M::process] read 693196 sequences (100000251 bp) in 2.350 CPU sec, 2.519 real sec...
sorting block 68, #reads = 1075194 mem = 536877681 peak = 1042575360
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 282463, 13, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 287, 534)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1296)
[M::mem_pestat] mean and std.dev: (336.32, 291.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1677)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 274, 397)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 837)
[M::mem_pestat] mean and std.dev: (298.42, 151.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1057)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (992, 992, 1244)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (488, 1748)
[M::mem_pestat] mean and std.dev: (1047.50, 97.29)
[M::mem_pestat] low and high boundaries for proper pairs: (236, 2000)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 386, 869)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2219)
[M::mem_pestat] mean and std.dev: (430.07, 391.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2894)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 693064 sequences (100000191 bp) in 3.088 CPU sec, 3.459 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 282183, 16, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 450, 805)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2047)
[M::mem_pestat] mean and std.dev: (584.58, 510.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2668)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 276, 400)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 844)
[M::mem_pestat] mean and std.dev: (300.44, 152.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1066)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (805, 1199, 1199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (17, 1987)
[M::mem_pestat] mean and std.dev: (882.07, 378.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2398)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (263, 339, 469)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 881)
[M::mem_pestat] mean and std.dev: (352.30, 166.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1087)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 693522 reads in 196.309 CPU sec, 6.324 real sec
sorting block 69, #reads = 1078404 mem = 536882900 peak = 1042575360
[M::mem_process_seqs] Processed 693196 reads in 136.794 CPU sec, 4.349 real sec
[M::process] read 692384 sequences (100000037 bp) in 2.149 CPU sec, 2.319 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 282392, 14, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 255, 414)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 926)
[M::mem_pestat] mean and std.dev: (274.47, 133.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1182)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 277, 402)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 850)
[M::mem_pestat] mean and std.dev: (301.29, 152.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1074)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (339, 739, 1299)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3219)
[M::mem_pestat] mean and std.dev: (777.77, 513.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4179)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 287, 545)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1299)
[M::mem_pestat] mean and std.dev: (283.85, 151.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1676)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 70, #reads = 1077813 mem = 536878167 peak = 1044529152
[M::process] read 691876 sequences (100000120 bp) in 3.221 CPU sec, 3.633 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 281982, 15, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (235, 312, 642)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1456)
[M::mem_pestat] mean and std.dev: (391.65, 247.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1863)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 279, 404)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 852)
[M::mem_pestat] mean and std.dev: (303.38, 153.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1076)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (99, 323, 1270)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3612)
[M::mem_pestat] mean and std.dev: (536.93, 592.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4783)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 311, 702)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1734)
[M::mem_pestat] mean and std.dev: (463.98, 368.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2250)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 693064 reads in 193.596 CPU sec, 6.307 real sec
[M::mem_process_seqs] Processed 692384 reads in 133.984 CPU sec, 4.336 real sec
[M::process] read 691880 sequences (100000064 bp) in 2.265 CPU sec, 2.376 real sec...
sorting block 71, #reads = 1077513 mem = 536881252 peak = 1044529152
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 282473, 22, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 292, 501)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1167)
[M::mem_pestat] mean and std.dev: (266.46, 129.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1500)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 281, 405)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 853)
[M::mem_pestat] mean and std.dev: (304.27, 153.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1077)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (450, 1085, 4003)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 11109)
[M::mem_pestat] mean and std.dev: (1988.18, 2030.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14662)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (249, 370, 617)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1353)
[M::mem_pestat] mean and std.dev: (388.61, 221.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1721)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 691512 sequences (100000013 bp) in 2.893 CPU sec, 3.350 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 281455, 22, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (136, 306, 409)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 955)
[M::mem_pestat] mean and std.dev: (247.00, 115.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1228)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 281, 406)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 856)
[M::mem_pestat] mean and std.dev: (305.00, 153.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1081)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (413, 1178, 2814)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7616)
[M::mem_pestat] mean and std.dev: (1674.00, 1507.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10017)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 286, 547)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1299)
[M::mem_pestat] mean and std.dev: (402.88, 295.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1675)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 691876 reads in 191.753 CPU sec, 6.214 real sec
[M::process] read 691236 sequences (100000233 bp) in 2.150 CPU sec, 2.262 real sec...
[M::mem_process_seqs] Processed 691880 reads in 130.747 CPU sec, 4.362 real sec
sorting block 72, #reads = 1077555 mem = 536878807 peak = 1044529152
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 282070, 16, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 222, 465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1063)
[M::mem_pestat] mean and std.dev: (307.50, 185.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1362)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 284, 407)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 855)
[M::mem_pestat] mean and std.dev: (306.13, 153.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1079)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (543, 753, 1369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3021)
[M::mem_pestat] mean and std.dev: (721.73, 501.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3847)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (315, 428, 1002)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2376)
[M::mem_pestat] mean and std.dev: (601.85, 445.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3063)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 692574 sequences (100000110 bp) in 2.740 CPU sec, 3.018 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 281878, 11, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 274, 572)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1318)
[M::mem_pestat] mean and std.dev: (321.54, 200.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1691)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 283, 407)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 855)
[M::mem_pestat] mean and std.dev: (306.23, 153.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1079)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (375, 1056, 2341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6273)
[M::mem_pestat] mean and std.dev: (1376.45, 1374.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8239)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 244, 414)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 900)
[M::mem_pestat] mean and std.dev: (230.03, 101.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1143)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 690550 sequences (100000248 bp) in 1.957 CPU sec, 2.031 real sec...
[M::mem_process_seqs] Processed 691512 reads in 198.053 CPU sec, 6.583 real sec
sorting block 73, #reads = 1076695 mem = 536876591 peak = 1044529152
[M::mem_process_seqs] Processed 691236 reads in 129.741 CPU sec, 4.267 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 281936, 18, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (142, 203, 788)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2080)
[M::mem_pestat] mean and std.dev: (385.16, 391.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2726)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 277, 401)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 845)
[M::mem_pestat] mean and std.dev: (301.56, 152.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1067)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (310, 1294, 3249)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9127)
[M::mem_pestat] mean and std.dev: (2034.61, 1867.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12066)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 476, 636)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1494)
[M::mem_pestat] mean and std.dev: (369.12, 176.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1923)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 74, #reads = 1076144 mem = 536879682 peak = 1044529152
[M::process] read 690484 sequences (100000214 bp) in 2.853 CPU sec, 3.064 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 281289, 13, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (144, 238, 449)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1059)
[M::mem_pestat] mean and std.dev: (236.28, 130.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1364)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 286, 411)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 863)
[M::mem_pestat] mean and std.dev: (308.89, 154.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1089)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (230, 395, 1776)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4868)
[M::mem_pestat] mean and std.dev: (726.77, 683.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6414)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 329, 521)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1155)
[M::mem_pestat] mean and std.dev: (329.14, 185.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1472)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 690676 sequences (100000105 bp) in 1.773 CPU sec, 1.822 real sec...
[M::mem_process_seqs] Processed 692574 reads in 196.943 CPU sec, 6.425 real sec
[M::mem_process_seqs] Processed 690550 reads in 132.919 CPU sec, 4.299 real sec
sorting block 75, #reads = 1076627 mem = 536878456 peak = 1044529152
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 281849, 28, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 340, 532)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1268)
[M::mem_pestat] mean and std.dev: (332.29, 198.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1636)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 287, 410)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 860)
[M::mem_pestat] mean and std.dev: (308.38, 153.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1085)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (225, 560, 895)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2235)
[M::mem_pestat] mean and std.dev: (581.39, 439.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2905)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (234, 331, 710)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1662)
[M::mem_pestat] mean and std.dev: (380.12, 242.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2138)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 690160 sequences (100000129 bp) in 2.614 CPU sec, 2.946 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 281075, 17, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 271, 511)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1171)
[M::mem_pestat] mean and std.dev: (302.04, 171.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1501)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 286, 410)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 860)
[M::mem_pestat] mean and std.dev: (308.46, 153.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1085)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (702, 879, 2501)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6099)
[M::mem_pestat] mean and std.dev: (1076.33, 1166.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7898)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (143, 234, 625)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1589)
[M::mem_pestat] mean and std.dev: (411.73, 406.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2071)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 690432 sequences (100000268 bp) in 1.882 CPU sec, 1.955 real sec...
[M::mem_process_seqs] Processed 690484 reads in 193.866 CPU sec, 6.232 real sec
[M::mem_process_seqs] Processed 690676 reads in 131.552 CPU sec, 4.244 real sec
sorting block 76, #reads = 1075263 mem = 536880465 peak = 1044529152
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 281130, 17, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 302, 533)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1251)
[M::mem_pestat] mean and std.dev: (303.10, 200.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1610)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 287, 411)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 863)
[M::mem_pestat] mean and std.dev: (309.00, 154.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1089)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (270, 824, 1508)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3984)
[M::mem_pestat] mean and std.dev: (762.06, 537.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5222)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 271, 484)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1130)
[M::mem_pestat] mean and std.dev: (313.27, 217.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1453)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 690096 sequences (100000241 bp) in 2.439 CPU sec, 2.779 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 281052, 28, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 460, 976)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2500)
[M::mem_pestat] mean and std.dev: (580.43, 500.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3262)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 285, 409)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 857)
[M::mem_pestat] mean and std.dev: (307.45, 152.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1081)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (526, 846, 3739)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10165)
[M::mem_pestat] mean and std.dev: (1811.93, 1868.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13378)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 413, 732)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1738)
[M::mem_pestat] mean and std.dev: (466.98, 352.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2241)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 690188 sequences (100000287 bp) in 1.904 CPU sec, 2.052 real sec...
[M::mem_process_seqs] Processed 690160 reads in 199.156 CPU sec, 6.483 real sec
[M::mem_process_seqs] Processed 690432 reads in 132.194 CPU sec, 4.251 real sec
sorting block 77, #reads = 1074445 mem = 536882999 peak = 1044529152
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 281219, 15, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 251, 392)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 844)
[M::mem_pestat] mean and std.dev: (261.45, 146.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1070)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 285, 406)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 848)
[M::mem_pestat] mean and std.dev: (306.93, 152.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1069)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (479, 716, 1116)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2390)
[M::mem_pestat] mean and std.dev: (635.00, 490.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3027)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 276, 405)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 883)
[M::mem_pestat] mean and std.dev: (284.06, 167.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1122)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 690340 sequences (100000294 bp) in 2.682 CPU sec, 3.019 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 281043, 22, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 335, 520)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1122)
[M::mem_pestat] mean and std.dev: (312.43, 170.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1423)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 283, 407)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 853)
[M::mem_pestat] mean and std.dev: (306.15, 152.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1076)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (362, 725, 1322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3242)
[M::mem_pestat] mean and std.dev: (738.55, 591.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4202)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 373, 588)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1388)
[M::mem_pestat] mean and std.dev: (384.08, 322.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1788)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 690020 sequences (100000043 bp) in 2.088 CPU sec, 2.104 real sec...
[M::mem_process_seqs] Processed 690096 reads in 194.448 CPU sec, 6.264 real sec
sorting block 78, #reads = 1074357 mem = 536879022 peak = 1044529152
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 280751, 17, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (238, 373, 669)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1531)
[M::mem_pestat] mean and std.dev: (355.93, 268.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1962)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 284, 407)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 853)
[M::mem_pestat] mean and std.dev: (307.01, 152.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1076)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (59, 319, 1198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3476)
[M::mem_pestat] mean and std.dev: (514.62, 676.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4615)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 307, 480)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1008)
[M::mem_pestat] mean and std.dev: (318.87, 167.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1272)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 690300 sequences (100000193 bp) in 2.330 CPU sec, 2.411 real sec...
[M::mem_process_seqs] Processed 690340 reads in 113.381 CPU sec, 3.917 real sec
sorting block 79, #reads = 1074648 mem = 536881057 peak = 1059905536
[M::mem_process_seqs] Processed 690188 reads in 285.785 CPU sec, 9.466 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 281188, 19, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 277, 570)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1396)
[M::mem_pestat] mean and std.dev: (376.39, 358.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1811)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 284, 408)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 854)
[M::mem_pestat] mean and std.dev: (306.94, 152.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1077)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (830, 1492, 2801)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6743)
[M::mem_pestat] mean and std.dev: (1661.53, 1360.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8714)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (249, 344, 574)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1224)
[M::mem_pestat] mean and std.dev: (349.61, 196.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1549)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 690044 sequences (100000114 bp) in 3.018 CPU sec, 3.706 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 281387, 10, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (256, 393, 561)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1171)
[M::mem_pestat] mean and std.dev: (390.45, 192.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1476)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 284, 407)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 853)
[M::mem_pestat] mean and std.dev: (306.83, 152.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1076)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (260, 427, 605)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1295)
[M::mem_pestat] mean and std.dev: (403.33, 193.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1640)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (250, 317, 543)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1129)
[M::mem_pestat] mean and std.dev: (336.23, 187.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1422)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 690020 reads in 220.848 CPU sec, 7.104 real sec
sorting block 80, #reads = 1075431 mem = 536878238 peak = 1059905536
[M::mem_process_seqs] Processed 690300 reads in 132.618 CPU sec, 4.269 real sec
[M::process] read 689848 sequences (100000211 bp) in 2.221 CPU sec, 2.431 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 281150, 22, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (142, 226, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 727)
[M::mem_pestat] mean and std.dev: (206.23, 96.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 922)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 284, 405)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 847)
[M::mem_pestat] mean and std.dev: (305.40, 150.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1068)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (523, 1164, 1334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2956)
[M::mem_pestat] mean and std.dev: (897.79, 496.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3767)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 385, 585)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1313)
[M::mem_pestat] mean and std.dev: (386.57, 239.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1677)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 81, #reads = 1074550 mem = 536880557 peak = 1059905536
[M::process] read 689590 sequences (100000058 bp) in 3.155 CPU sec, 3.629 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 280444, 15, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 274, 591)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1427)
[M::mem_pestat] mean and std.dev: (347.33, 273.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1845)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 284, 406)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 848)
[M::mem_pestat] mean and std.dev: (306.36, 151.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1069)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (767, 795, 1856)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4034)
[M::mem_pestat] mean and std.dev: (1248.87, 955.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5123)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 344, 1153)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3077)
[M::mem_pestat] mean and std.dev: (546.58, 520.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4039)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 690044 reads in 198.610 CPU sec, 6.448 real sec
[M::mem_process_seqs] Processed 689848 reads in 133.735 CPU sec, 4.320 real sec
[M::process] read 689684 sequences (100000221 bp) in 2.263 CPU sec, 2.425 real sec...
sorting block 82, #reads = 1074317 mem = 536882091 peak = 1059905536
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 280700, 22, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (226, 421, 1466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3946)
[M::mem_pestat] mean and std.dev: (605.00, 539.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5186)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 285, 407)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 849)
[M::mem_pestat] mean and std.dev: (307.14, 151.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1070)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (512, 1300, 2277)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5807)
[M::mem_pestat] mean and std.dev: (1322.45, 964.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7572)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (234, 360, 986)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2490)
[M::mem_pestat] mean and std.dev: (606.41, 608.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3242)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 689308 sequences (100000013 bp) in 2.773 CPU sec, 3.091 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 281313, 13, 72)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 310, 1042)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2800)
[M::mem_pestat] mean and std.dev: (662.18, 767.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3734)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 286, 407)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 849)
[M::mem_pestat] mean and std.dev: (307.05, 150.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1070)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (324, 1166, 5418)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 15606)
[M::mem_pestat] mean and std.dev: (1985.62, 2283.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 20700)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (233, 363, 555)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1199)
[M::mem_pestat] mean and std.dev: (321.31, 146.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1521)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 689080 sequences (100000267 bp) in 1.828 CPU sec, 1.902 real sec...
[M::mem_process_seqs] Processed 689590 reads in 205.717 CPU sec, 6.640 real sec
[M::mem_process_seqs] Processed 689684 reads in 137.929 CPU sec, 4.505 real sec
sorting block 83, #reads = 1073068 mem = 536881516 peak = 1059905536
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 280718, 21, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 314, 1065)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2871)
[M::mem_pestat] mean and std.dev: (448.33, 479.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3774)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 287, 407)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 847)
[M::mem_pestat] mean and std.dev: (307.70, 151.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1067)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (617, 1538, 2213)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5405)
[M::mem_pestat] mean and std.dev: (1326.33, 885.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7001)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (265, 413, 1336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3478)
[M::mem_pestat] mean and std.dev: (704.53, 623.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4549)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 689132 sequences (100000179 bp) in 2.405 CPU sec, 2.520 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 280934, 24, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (277, 447, 845)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1981)
[M::mem_pestat] mean and std.dev: (581.10, 339.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2549)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 287, 407)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 847)
[M::mem_pestat] mean and std.dev: (308.10, 151.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1067)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (235, 818, 1959)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5407)
[M::mem_pestat] mean and std.dev: (1014.57, 897.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7131)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 266, 501)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1087)
[M::mem_pestat] mean and std.dev: (311.80, 198.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1380)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 689342 sequences (100000203 bp) in 1.540 CPU sec, 1.546 real sec...
[M::mem_process_seqs] Processed 689308 reads in 172.728 CPU sec, 5.593 real sec
sorting block 84, #reads = 1073348 mem = 536880468 peak = 1059905536
[M::mem_process_seqs] Processed 689080 reads in 110.695 CPU sec, 3.509 real sec
sorting block 85, #reads = 1074466 mem = 536882543 peak = 1059905536
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 280563, 25, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 244, 379)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 711)
[M::mem_pestat] mean and std.dev: (267.00, 111.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 877)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 286, 404)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 836)
[M::mem_pestat] mean and std.dev: (306.79, 149.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1052)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (768, 827, 1633)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3363)
[M::mem_pestat] mean and std.dev: (890.10, 375.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4228)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 200, 811)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2075)
[M::mem_pestat] mean and std.dev: (437.79, 358.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2707)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 688844 sequences (100000173 bp) in 2.444 CPU sec, 2.627 real sec...
[M::process] read 688474 sequences (100000288 bp) in 2.113 CPU sec, 2.121 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 280891, 39, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 294, 701)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1807)
[M::mem_pestat] mean and std.dev: (421.76, 309.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2360)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 286, 404)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 836)
[M::mem_pestat] mean and std.dev: (306.68, 149.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1052)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (340, 496, 572)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1036)
[M::mem_pestat] mean and std.dev: (409.00, 191.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1268)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 318, 612)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1492)
[M::mem_pestat] mean and std.dev: (374.00, 277.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1932)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 689132 reads in 180.253 CPU sec, 5.751 real sec
[M::mem_process_seqs] Processed 689342 reads in 129.828 CPU sec, 4.388 real sec
sorting block 86, #reads = 1073724 mem = 536878588 peak = 1059905536
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 280703, 11, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 320, 505)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1173)
[M::mem_pestat] mean and std.dev: (287.89, 145.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1507)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 288, 407)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 843)
[M::mem_pestat] mean and std.dev: (308.67, 150.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1061)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (429, 702, 1762)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4428)
[M::mem_pestat] mean and std.dev: (788.90, 594.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5761)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (238, 298, 637)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1435)
[M::mem_pestat] mean and std.dev: (370.24, 210.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1834)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 688456 sequences (100000032 bp) in 2.852 CPU sec, 3.219 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 280547, 18, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 289, 590)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1346)
[M::mem_pestat] mean and std.dev: (382.20, 270.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1724)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 292, 412)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 858)
[M::mem_pestat] mean and std.dev: (311.56, 152.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1081)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (339, 639, 1306)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3240)
[M::mem_pestat] mean and std.dev: (683.00, 505.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4207)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 298, 408)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 814)
[M::mem_pestat] mean and std.dev: (307.33, 152.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1017)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 688418 sequences (100000105 bp) in 1.968 CPU sec, 1.983 real sec...
[M::mem_process_seqs] Processed 688844 reads in 199.088 CPU sec, 6.629 real sec
[M::mem_process_seqs] Processed 688474 reads in 131.285 CPU sec, 4.202 real sec
sorting block 87, #reads = 1072824 mem = 536876975 peak = 1059905536
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 280423, 14, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 325, 480)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1014)
[M::mem_pestat] mean and std.dev: (349.81, 208.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1281)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 293, 414)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 862)
[M::mem_pestat] mean and std.dev: (313.15, 153.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1086)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (9, 676, 1894)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5664)
[M::mem_pestat] mean and std.dev: (1086.21, 1262.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7549)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (294, 376, 565)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1107)
[M::mem_pestat] mean and std.dev: (405.81, 183.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1378)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696692 sequences (100000049 bp) in 2.889 CPU sec, 3.205 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 280688, 23, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 415, 1017)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2671)
[M::mem_pestat] mean and std.dev: (514.50, 479.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3498)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 294, 416)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 866)
[M::mem_pestat] mean and std.dev: (314.60, 154.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1091)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (533, 628, 1575)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3659)
[M::mem_pestat] mean and std.dev: (704.89, 790.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4701)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (234, 316, 607)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1353)
[M::mem_pestat] mean and std.dev: (344.38, 181.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1726)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 688456 reads in 189.378 CPU sec, 6.178 real sec
[M::process] read 698836 sequences (100000179 bp) in 2.011 CPU sec, 2.074 real sec...
[M::mem_process_seqs] Processed 688418 reads in 136.423 CPU sec, 4.393 real sec
sorting block 88, #reads = 1073198 mem = 536878668 peak = 1059905536
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 283739, 19, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 314, 764)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1996)
[M::mem_pestat] mean and std.dev: (510.50, 462.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2612)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 261, 387)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 821)
[M::mem_pestat] mean and std.dev: (289.71, 150.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1038)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (254, 575, 2229)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6179)
[M::mem_pestat] mean and std.dev: (1108.05, 1377.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8154)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 328, 519)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1147)
[M::mem_pestat] mean and std.dev: (350.73, 215.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1461)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697500 sequences (100000016 bp) in 2.889 CPU sec, 3.193 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 284980, 14, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 339, 712)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1776)
[M::mem_pestat] mean and std.dev: (422.67, 337.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2308)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 252, 378)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 804)
[M::mem_pestat] mean and std.dev: (283.47, 149.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1017)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (355, 465, 1445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3625)
[M::mem_pestat] mean and std.dev: (918.79, 909.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4715)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 312, 637)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1543)
[M::mem_pestat] mean and std.dev: (351.44, 224.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1996)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696780 sequences (100000185 bp) in 1.973 CPU sec, 1.997 real sec...
[M::mem_process_seqs] Processed 696692 reads in 203.076 CPU sec, 6.538 real sec
sorting block 89, #reads = 1073764 mem = 536878558 peak = 1059905536
[M::mem_process_seqs] Processed 698836 reads in 134.783 CPU sec, 4.312 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 284791, 20, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 283, 1388)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3764)
[M::mem_pestat] mean and std.dev: (791.35, 934.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4952)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 256, 384)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 818)
[M::mem_pestat] mean and std.dev: (286.92, 150.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1035)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (281, 397, 1589)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4205)
[M::mem_pestat] mean and std.dev: (1008.95, 1278.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6123)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 287, 638)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1550)
[M::mem_pestat] mean and std.dev: (421.87, 377.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2006)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 90, #reads = 1076313 mem = 536881167 peak = 1059905536
[M::process] read 695996 sequences (100000093 bp) in 2.688 CPU sec, 2.904 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 283984, 15, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 467, 760)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1942)
[M::mem_pestat] mean and std.dev: (555.00, 460.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2533)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 260, 388)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 826)
[M::mem_pestat] mean and std.dev: (290.04, 151.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1045)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (134, 479, 520)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1292)
[M::mem_pestat] mean and std.dev: (397.21, 271.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1678)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 359, 1496)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4080)
[M::mem_pestat] mean and std.dev: (806.47, 937.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5372)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695368 sequences (100000293 bp) in 1.869 CPU sec, 2.082 real sec...
[M::mem_process_seqs] Processed 697500 reads in 191.027 CPU sec, 6.129 real sec
[M::mem_process_seqs] Processed 696780 reads in 129.225 CPU sec, 4.142 real sec
sorting block 91, #reads = 1078358 mem = 536878163 peak = 1059905536
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 283871, 22, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 291, 400)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 766)
[M::mem_pestat] mean and std.dev: (296.17, 114.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 949)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 264, 391)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 831)
[M::mem_pestat] mean and std.dev: (292.40, 151.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1051)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (561, 1787, 4154)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 11340)
[M::mem_pestat] mean and std.dev: (2712.95, 2747.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14933)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (255, 281, 435)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 795)
[M::mem_pestat] mean and std.dev: (307.71, 119.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 975)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694616 sequences (100000228 bp) in 2.870 CPU sec, 3.163 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 283608, 15, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 350, 753)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1953)
[M::mem_pestat] mean and std.dev: (327.02, 231.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2553)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 267, 393)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 835)
[M::mem_pestat] mean and std.dev: (294.12, 151.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1056)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (737, 1614, 4847)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13067)
[M::mem_pestat] mean and std.dev: (2396.00, 2502.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17177)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 378, 685)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1615)
[M::mem_pestat] mean and std.dev: (458.63, 333.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2080)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695996 reads in 189.694 CPU sec, 6.100 real sec
[M::process] read 694216 sequences (100000171 bp) in 2.166 CPU sec, 2.190 real sec...
[M::mem_process_seqs] Processed 695368 reads in 119.234 CPU sec, 3.969 real sec
sorting block 92, #reads = 1079357 mem = 536876727 peak = 1059905536
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 283665, 21, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (139, 302, 540)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1342)
[M::mem_pestat] mean and std.dev: (321.92, 230.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1743)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 270, 398)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 846)
[M::mem_pestat] mean and std.dev: (297.23, 153.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1070)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 943, 1591)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4477)
[M::mem_pestat] mean and std.dev: (1040.90, 990.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5920)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 343, 716)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1696)
[M::mem_pestat] mean and std.dev: (453.32, 370.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2186)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 693934 sequences (100000261 bp) in 2.596 CPU sec, 2.730 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 282782, 38, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 386, 612)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1440)
[M::mem_pestat] mean and std.dev: (360.86, 234.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1854)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 271, 399)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 849)
[M::mem_pestat] mean and std.dev: (298.34, 153.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1074)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (365, 680, 1533)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3869)
[M::mem_pestat] mean and std.dev: (732.32, 708.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5037)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 345, 510)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1096)
[M::mem_pestat] mean and std.dev: (333.12, 168.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1389)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 693018 sequences (100000051 bp) in 1.860 CPU sec, 1.865 real sec...
[M::mem_process_seqs] Processed 694616 reads in 177.710 CPU sec, 5.821 real sec
sorting block 93, #reads = 1076939 mem = 536880432 peak = 1059905536
[M::mem_process_seqs] Processed 694216 reads in 120.736 CPU sec, 3.822 real sec
sorting block 94, #reads = 1074132 mem = 536880847 peak = 1059905536
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 283289, 14, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 202, 421)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 969)
[M::mem_pestat] mean and std.dev: (218.94, 101.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1243)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 274, 403)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 857)
[M::mem_pestat] mean and std.dev: (301.10, 155.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1084)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (479, 632, 874)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1664)
[M::mem_pestat] mean and std.dev: (606.08, 398.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2200)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (259, 405, 656)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1450)
[M::mem_pestat] mean and std.dev: (476.74, 278.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1847)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 692544 sequences (100000119 bp) in 2.896 CPU sec, 3.043 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 282613, 14, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 339, 1388)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3772)
[M::mem_pestat] mean and std.dev: (1061.11, 1258.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6096)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 277, 406)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 862)
[M::mem_pestat] mean and std.dev: (303.58, 156.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1090)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (336, 471, 556)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 996)
[M::mem_pestat] mean and std.dev: (397.64, 138.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1216)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (234, 397, 717)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1683)
[M::mem_pestat] mean and std.dev: (564.00, 445.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2346)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 692458 sequences (100000050 bp) in 1.880 CPU sec, 1.875 real sec...
[M::mem_process_seqs] Processed 693934 reads in 169.432 CPU sec, 5.373 real sec
[M::mem_process_seqs] Processed 693018 reads in 122.848 CPU sec, 3.907 real sec
sorting block 95, #reads = 1074862 mem = 536877380 peak = 1059905536
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 282623, 21, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 350, 810)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2004)
[M::mem_pestat] mean and std.dev: (374.08, 276.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2601)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 279, 408)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 866)
[M::mem_pestat] mean and std.dev: (305.07, 156.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1095)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (135, 419, 478)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1164)
[M::mem_pestat] mean and std.dev: (309.22, 203.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1507)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (285, 302, 389)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (77, 597)
[M::mem_pestat] mean and std.dev: (299.03, 119.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 779)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 691804 sequences (100000069 bp) in 2.366 CPU sec, 2.475 real sec...
[M::process] read 692170 sequences (100000023 bp) in 1.580 CPU sec, 1.583 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 282574, 22, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 311, 658)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1622)
[M::mem_pestat] mean and std.dev: (351.00, 279.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2104)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 280, 409)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 869)
[M::mem_pestat] mean and std.dev: (305.76, 156.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1099)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (109, 425, 1269)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3589)
[M::mem_pestat] mean and std.dev: (676.00, 754.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4749)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 223, 350)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 724)
[M::mem_pestat] mean and std.dev: (223.97, 81.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 911)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 692544 reads in 174.036 CPU sec, 5.539 real sec
[M::mem_process_seqs] Processed 692458 reads in 115.930 CPU sec, 3.680 real sec
sorting block 96, #reads = 1075669 mem = 536880448 peak = 1059905536
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 282380, 17, 76)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 279, 421)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 869)
[M::mem_pestat] mean and std.dev: (285.86, 138.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1093)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 281, 411)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 871)
[M::mem_pestat] mean and std.dev: (306.72, 155.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1101)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (351, 788, 1488)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3762)
[M::mem_pestat] mean and std.dev: (956.53, 766.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4899)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 377, 610)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1342)
[M::mem_pestat] mean and std.dev: (392.50, 197.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1708)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 691938 sequences (100000062 bp) in 2.521 CPU sec, 2.643 real sec...
[M::process] read 691402 sequences (100000269 bp) in 1.540 CPU sec, 1.541 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 282183, 20, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 229, 370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 810)
[M::mem_pestat] mean and std.dev: (235.72, 141.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1030)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 280, 411)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 873)
[M::mem_pestat] mean and std.dev: (306.63, 156.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1104)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (646, 1014, 1249)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2455)
[M::mem_pestat] mean and std.dev: (838.25, 353.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3058)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (257, 437, 891)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2159)
[M::mem_pestat] mean and std.dev: (553.38, 447.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2793)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 691804 reads in 176.189 CPU sec, 5.654 real sec
sorting block 97, #reads = 1075067 mem = 536880440 peak = 1059905536
[M::mem_process_seqs] Processed 692170 reads in 112.879 CPU sec, 3.689 real sec
sorting block 98, #reads = 1072525 mem = 536879384 peak = 1059905536
[M::process] read 691208 sequences (100000078 bp) in 2.452 CPU sec, 2.585 real sec...
[M::process] read 691296 sequences (100000200 bp) in 1.600 CPU sec, 1.607 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 282093, 11, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 243, 375)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 783)
[M::mem_pestat] mean and std.dev: (270.52, 128.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 987)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 284, 413)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 875)
[M::mem_pestat] mean and std.dev: (308.73, 157.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1106)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (254, 729, 1527)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4073)
[M::mem_pestat] mean and std.dev: (588.22, 474.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5346)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 223, 554)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1326)
[M::mem_pestat] mean and std.dev: (323.62, 230.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1712)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 691402 reads in 91.920 CPU sec, 2.941 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 281735, 17, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 233, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 661)
[M::mem_pestat] mean and std.dev: (223.05, 96.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 829)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 282, 412)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 874)
[M::mem_pestat] mean and std.dev: (307.65, 157.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1105)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (327, 1715, 1915)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5091)
[M::mem_pestat] mean and std.dev: (1427.65, 994.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6679)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 354, 462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1052)
[M::mem_pestat] mean and std.dev: (339.74, 179.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1347)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 281846, 33, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 265, 484)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1146)
[M::mem_pestat] mean and std.dev: (320.38, 232.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1477)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 284, 413)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 875)
[M::mem_pestat] mean and std.dev: (309.00, 156.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1106)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (243, 956, 2461)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6897)
[M::mem_pestat] mean and std.dev: (1293.50, 1364.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9115)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (230, 330, 623)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1409)
[M::mem_pestat] mean and std.dev: (373.85, 265.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1802)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 690934 sequences (100000004 bp) in 2.190 CPU sec, 2.200 real sec...
[M::mem_process_seqs] Processed 691938 reads in 271.297 CPU sec, 8.728 real sec
sorting block 99, #reads = 1072558 mem = 536884098 peak = 1059905536
[M::mem_process_seqs] Processed 691208 reads in 142.892 CPU sec, 4.596 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 281638, 17, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 407, 1214)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3284)
[M::mem_pestat] mean and std.dev: (625.06, 659.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4319)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 283, 410)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 866)
[M::mem_pestat] mean and std.dev: (307.49, 155.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1094)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (95, 462, 1056)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2978)
[M::mem_pestat] mean and std.dev: (469.60, 418.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3939)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (284, 770, 1393)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3611)
[M::mem_pestat] mean and std.dev: (855.05, 789.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4720)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 690736 sequences (100000240 bp) in 3.265 CPU sec, 3.482 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 281125, 14, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 276, 537)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1207)
[M::mem_pestat] mean and std.dev: (320.24, 192.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1542)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 284, 412)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 870)
[M::mem_pestat] mean and std.dev: (308.66, 156.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1099)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (509, 1523, 2891)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7655)
[M::mem_pestat] mean and std.dev: (1480.64, 1125.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10037)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 221, 522)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1178)
[M::mem_pestat] mean and std.dev: (275.61, 148.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1506)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 690876 sequences (100000059 bp) in 2.050 CPU sec, 2.047 real sec...
[M::mem_process_seqs] Processed 691296 reads in 200.334 CPU sec, 6.353 real sec
sorting block 100, #reads = 1073205 mem = 536879005 peak = 1059905536
[M::mem_process_seqs] Processed 690934 reads in 136.243 CPU sec, 4.324 real sec
sorting block 101, #reads = 1071522 mem = 536878535 peak = 1096695808
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 281500, 19, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 232, 499)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1097)
[M::mem_pestat] mean and std.dev: (252.39, 171.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1396)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 284, 410)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 862)
[M::mem_pestat] mean and std.dev: (308.41, 155.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1088)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (470, 499, 1457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3431)
[M::mem_pestat] mean and std.dev: (893.79, 707.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4418)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 262, 310)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 574)
[M::mem_pestat] mean and std.dev: (240.12, 91.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 706)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 690828 sequences (100000006 bp) in 3.059 CPU sec, 3.272 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 282276, 14, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (226, 395, 634)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1450)
[M::mem_pestat] mean and std.dev: (457.35, 303.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1858)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 283, 409)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 861)
[M::mem_pestat] mean and std.dev: (307.10, 154.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1087)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (518, 598, 879)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1601)
[M::mem_pestat] mean and std.dev: (622.08, 370.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2103)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 431, 959)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2461)
[M::mem_pestat] mean and std.dev: (516.89, 381.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3212)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 691172 sequences (100000206 bp) in 2.094 CPU sec, 2.101 real sec...
[M::mem_process_seqs] Processed 690736 reads in 205.226 CPU sec, 6.757 real sec
[M::mem_process_seqs] Processed 690876 reads in 134.868 CPU sec, 4.276 real sec
sorting block 102, #reads = 1073439 mem = 536882728 peak = 1096695808
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 281374, 21, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (234, 311, 833)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2031)
[M::mem_pestat] mean and std.dev: (477.33, 458.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2630)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 283, 409)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 861)
[M::mem_pestat] mean and std.dev: (307.12, 153.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1087)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (555, 820, 2066)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5088)
[M::mem_pestat] mean and std.dev: (1221.11, 1096.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6599)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 286, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 617)
[M::mem_pestat] mean and std.dev: (235.14, 74.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 759)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 690850 sequences (100000002 bp) in 3.003 CPU sec, 3.211 real sec...
[M::process] read 690334 sequences (100000010 bp) in 1.751 CPU sec, 1.757 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 281532, 10, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (131, 342, 412)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 974)
[M::mem_pestat] mean and std.dev: (283.80, 177.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1255)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 282, 409)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 863)
[M::mem_pestat] mean and std.dev: (306.21, 154.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1090)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (472, 689, 1372)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3172)
[M::mem_pestat] mean and std.dev: (631.62, 381.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4072)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 280, 734)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1818)
[M::mem_pestat] mean and std.dev: (347.58, 295.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2360)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 690828 reads in 208.663 CPU sec, 6.747 real sec
sorting block 103, #reads = 1071553 mem = 536884076 peak = 1096695808
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 281905, 22, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 358, 1044)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2670)
[M::mem_pestat] mean and std.dev: (509.58, 471.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3483)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 285, 411)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 865)
[M::mem_pestat] mean and std.dev: (308.26, 154.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1092)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (303, 543, 995)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2379)
[M::mem_pestat] mean and std.dev: (756.32, 616.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3224)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 297, 615)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1489)
[M::mem_pestat] mean and std.dev: (355.15, 272.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1926)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 690572 sequences (100000015 bp) in 2.280 CPU sec, 2.289 real sec...
[M::mem_process_seqs] Processed 690850 reads in 118.685 CPU sec, 3.852 real sec
[M::mem_process_seqs] Processed 691172 reads in 297.185 CPU sec, 9.568 real sec
sorting block 104, #reads = 1072171 mem = 536885234 peak = 1096695808
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 281387, 10, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 397, 535)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1221)
[M::mem_pestat] mean and std.dev: (377.23, 252.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1564)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 285, 408)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 854)
[M::mem_pestat] mean and std.dev: (307.12, 151.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1077)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (63, 1041, 1041)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2997)
[M::mem_pestat] mean and std.dev: (818.10, 712.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3975)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 286, 558)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1324)
[M::mem_pestat] mean and std.dev: (293.07, 158.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1707)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 690398 sequences (100000250 bp) in 2.829 CPU sec, 3.157 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 280928, 19, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 338, 933)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2375)
[M::mem_pestat] mean and std.dev: (585.66, 571.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3096)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 283, 407)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 853)
[M::mem_pestat] mean and std.dev: (306.21, 152.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1076)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (95, 97, 1782)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5156)
[M::mem_pestat] mean and std.dev: (885.32, 1288.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6843)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 325, 416)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 824)
[M::mem_pestat] mean and std.dev: (271.80, 89.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1028)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 690478 sequences (100000013 bp) in 1.655 CPU sec, 1.669 real sec...
[M::mem_process_seqs] Processed 690334 reads in 230.124 CPU sec, 7.330 real sec
[M::mem_process_seqs] Processed 690572 reads in 134.580 CPU sec, 4.262 real sec
sorting block 105, #reads = 1072247 mem = 536879623 peak = 1096695808
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 280667, 23, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 324, 569)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1361)
[M::mem_pestat] mean and std.dev: (364.11, 266.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1757)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 282, 404)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 844)
[M::mem_pestat] mean and std.dev: (305.01, 151.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1064)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (547, 830, 1250)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2656)
[M::mem_pestat] mean and std.dev: (654.75, 411.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3359)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 353, 734)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1820)
[M::mem_pestat] mean and std.dev: (454.22, 395.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2363)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 690430 sequences (100000177 bp) in 2.617 CPU sec, 2.796 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (73, 281148, 22, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 325, 1305)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3587)
[M::mem_pestat] mean and std.dev: (674.37, 743.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4728)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 282, 402)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 838)
[M::mem_pestat] mean and std.dev: (303.92, 149.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1056)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (132, 516, 1318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3690)
[M::mem_pestat] mean and std.dev: (845.09, 889.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4876)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 315, 610)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1388)
[M::mem_pestat] mean and std.dev: (361.92, 237.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1777)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 690306 sequences (100000141 bp) in 1.959 CPU sec, 1.958 real sec...
[M::mem_process_seqs] Processed 690398 reads in 178.720 CPU sec, 5.670 real sec
sorting block 106, #reads = 1070426 mem = 536879116 peak = 1096695808
[M::mem_process_seqs] Processed 690478 reads in 116.764 CPU sec, 3.700 real sec
sorting block 107, #reads = 1070879 mem = 536879162 peak = 1096695808
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 281463, 25, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 443, 498)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1168)
[M::mem_pestat] mean and std.dev: (402.75, 220.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1503)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 283, 404)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 844)
[M::mem_pestat] mean and std.dev: (304.85, 150.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1064)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (560, 739, 2875)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7505)
[M::mem_pestat] mean and std.dev: (1418.71, 1335.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9820)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 270, 579)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1307)
[M::mem_pestat] mean and std.dev: (337.20, 244.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1671)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 690462 sequences (100000108 bp) in 2.455 CPU sec, 2.569 real sec...
[M::process] read 690406 sequences (100000246 bp) in 1.700 CPU sec, 1.701 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 281793, 25, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 285, 454)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1030)
[M::mem_pestat] mean and std.dev: (268.93, 162.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1318)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 283, 405)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 847)
[M::mem_pestat] mean and std.dev: (305.69, 152.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1068)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (411, 727, 1990)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5148)
[M::mem_pestat] mean and std.dev: (955.87, 1055.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6727)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 307, 722)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1738)
[M::mem_pestat] mean and std.dev: (463.93, 363.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2246)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 690430 reads in 174.036 CPU sec, 5.766 real sec
[M::mem_process_seqs] Processed 690306 reads in 116.326 CPU sec, 3.720 real sec
sorting block 108, #reads = 1071428 mem = 536880696 peak = 1096695808
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 281560, 21, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 334, 453)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1005)
[M::mem_pestat] mean and std.dev: (293.54, 182.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1281)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 284, 406)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 850)
[M::mem_pestat] mean and std.dev: (306.53, 153.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1072)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (396, 856, 2359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6285)
[M::mem_pestat] mean and std.dev: (1261.48, 1034.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8248)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (243, 348, 601)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1317)
[M::mem_pestat] mean and std.dev: (369.17, 187.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1675)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 692694 sequences (100000151 bp) in 2.398 CPU sec, 2.519 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 280962, 19, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 454, 1119)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3059)
[M::mem_pestat] mean and std.dev: (680.96, 695.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4029)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 283, 408)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 856)
[M::mem_pestat] mean and std.dev: (307.32, 154.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1080)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (457, 821, 2586)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6844)
[M::mem_pestat] mean and std.dev: (1860.74, 2087.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10209)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 414, 1066)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2792)
[M::mem_pestat] mean and std.dev: (615.34, 654.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3655)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701926 sequences (100000254 bp) in 1.930 CPU sec, 1.930 real sec...
[M::mem_process_seqs] Processed 690462 reads in 162.787 CPU sec, 5.159 real sec
sorting block 109, #reads = 1071039 mem = 536878910 peak = 1096695808
[M::mem_process_seqs] Processed 690406 reads in 118.046 CPU sec, 3.763 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 281762, 31, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 438, 588)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1324)
[M::mem_pestat] mean and std.dev: (402.16, 200.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1692)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 276, 403)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 853)
[M::mem_pestat] mean and std.dev: (302.09, 154.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1078)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (483, 1140, 3095)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8319)
[M::mem_pestat] mean and std.dev: (1778.37, 1960.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10931)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 298, 534)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1302)
[M::mem_pestat] mean and std.dev: (286.56, 198.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1686)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699358 sequences (100000161 bp) in 2.150 CPU sec, 2.218 real sec...
[M::process] read 698434 sequences (100000002 bp) in 1.920 CPU sec, 1.919 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 285729, 15, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 266, 602)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1436)
[M::mem_pestat] mean and std.dev: (353.00, 275.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1853)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 242, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 763)
[M::mem_pestat] mean and std.dev: (271.70, 142.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 964)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (815, 818, 988)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (469, 1334)
[M::mem_pestat] mean and std.dev: (933.30, 137.95)
[M::mem_pestat] low and high boundaries for proper pairs: (296, 1507)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (240, 316, 1215)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3165)
[M::mem_pestat] mean and std.dev: (510.16, 416.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4140)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 692694 reads in 169.026 CPU sec, 5.356 real sec
sorting block 110, #reads = 1069548 mem = 536880136 peak = 1096695808
[M::mem_process_seqs] Processed 701926 reads in 114.663 CPU sec, 3.640 real sec
sorting block 111, #reads = 1072058 mem = 536879519 peak = 1096695808
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 284781, 16, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 329, 543)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1227)
[M::mem_pestat] mean and std.dev: (345.72, 181.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1569)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 250, 371)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 787)
[M::mem_pestat] mean and std.dev: (278.96, 144.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 995)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (123, 542, 897)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2445)
[M::mem_pestat] mean and std.dev: (529.62, 452.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3219)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 252, 806)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2052)
[M::mem_pestat] mean and std.dev: (376.85, 307.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2675)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696920 sequences (100000267 bp) in 2.224 CPU sec, 2.354 real sec...
[M::process] read 696420 sequences (100000051 bp) in 1.470 CPU sec, 1.467 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 284760, 13, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (139, 218, 411)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 955)
[M::mem_pestat] mean and std.dev: (213.27, 116.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1227)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 256, 377)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 797)
[M::mem_pestat] mean and std.dev: (283.09, 146.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1007)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (387, 678, 1379)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3363)
[M::mem_pestat] mean and std.dev: (842.46, 706.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4355)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 492, 657)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1611)
[M::mem_pestat] mean and std.dev: (456.31, 305.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2088)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699358 reads in 169.207 CPU sec, 5.382 real sec
[M::mem_process_seqs] Processed 698434 reads in 112.084 CPU sec, 3.572 real sec
sorting block 112, #reads = 1074575 mem = 536880194 peak = 1096695808
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 284629, 20, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 265, 655)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1571)
[M::mem_pestat] mean and std.dev: (347.38, 276.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2029)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 259, 380)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 802)
[M::mem_pestat] mean and std.dev: (285.82, 146.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1013)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (306, 771, 1937)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5199)
[M::mem_pestat] mean and std.dev: (1220.55, 1332.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6830)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (233, 527, 1173)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3053)
[M::mem_pestat] mean and std.dev: (630.35, 554.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3993)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696242 sequences (100000140 bp) in 2.509 CPU sec, 2.636 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 283354, 11, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 358, 1831)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5083)
[M::mem_pestat] mean and std.dev: (773.32, 1040.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6709)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 262, 385)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 815)
[M::mem_pestat] mean and std.dev: (289.10, 148.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1030)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (312, 665, 5337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 15387)
[M::mem_pestat] mean and std.dev: (2800.73, 3170.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 20412)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 360, 583)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1293)
[M::mem_pestat] mean and std.dev: (392.54, 224.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1648)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696520 sequences (100000098 bp) in 1.860 CPU sec, 1.862 real sec...
[M::mem_process_seqs] Processed 696920 reads in 161.842 CPU sec, 5.138 real sec
[M::mem_process_seqs] Processed 696420 reads in 108.133 CPU sec, 3.689 real sec
sorting block 113, #reads = 1072849 mem = 536877919 peak = 1096695808
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 284251, 13, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 336, 581)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1391)
[M::mem_pestat] mean and std.dev: (378.00, 270.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1796)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 261, 385)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 815)
[M::mem_pestat] mean and std.dev: (288.58, 147.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1030)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (106, 783, 1372)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3904)
[M::mem_pestat] mean and std.dev: (814.58, 689.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5170)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (236, 406, 625)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1403)
[M::mem_pestat] mean and std.dev: (409.28, 253.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1792)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696546 sequences (100000217 bp) in 2.453 CPU sec, 2.563 real sec...
[M::process] read 695088 sequences (100000281 bp) in 1.620 CPU sec, 1.618 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 283984, 18, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 233, 429)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 953)
[M::mem_pestat] mean and std.dev: (244.88, 128.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1215)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 260, 385)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 815)
[M::mem_pestat] mean and std.dev: (287.95, 147.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1030)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (439, 1052, 1293)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3001)
[M::mem_pestat] mean and std.dev: (883.69, 586.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3855)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 336, 429)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 897)
[M::mem_pestat] mean and std.dev: (296.70, 117.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1131)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696242 reads in 171.544 CPU sec, 5.712 real sec
sorting block 114, #reads = 1074268 mem = 536880362 peak = 1096695808
[M::mem_process_seqs] Processed 696520 reads in 113.872 CPU sec, 3.620 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 284170, 16, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 415, 515)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1195)
[M::mem_pestat] mean and std.dev: (340.15, 188.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1535)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 262, 386)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 818)
[M::mem_pestat] mean and std.dev: (289.17, 148.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1034)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (352, 1228, 1401)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3499)
[M::mem_pestat] mean and std.dev: (929.21, 600.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4548)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (239, 452, 660)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1502)
[M::mem_pestat] mean and std.dev: (386.67, 210.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1923)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694186 sequences (100000036 bp) in 2.593 CPU sec, 2.706 real sec...
[M::process] read 694074 sequences (100000275 bp) in 1.994 CPU sec, 2.004 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 283732, 15, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 366, 504)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1096)
[M::mem_pestat] mean and std.dev: (362.23, 207.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1392)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 267, 395)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 839)
[M::mem_pestat] mean and std.dev: (294.69, 151.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1061)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (246, 475, 1483)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3957)
[M::mem_pestat] mean and std.dev: (623.43, 568.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5194)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (270, 467, 1606)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4278)
[M::mem_pestat] mean and std.dev: (809.40, 750.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5614)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696546 reads in 192.782 CPU sec, 6.112 real sec
sorting block 115, #reads = 1073032 mem = 536880308 peak = 1096695808
[M::mem_process_seqs] Processed 695088 reads in 132.199 CPU sec, 4.200 real sec
sorting block 116, #reads = 1072263 mem = 536879423 peak = 1098113024
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 283207, 22, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 304, 1031)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2707)
[M::mem_pestat] mean and std.dev: (519.70, 468.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3545)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 271, 397)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 841)
[M::mem_pestat] mean and std.dev: (296.70, 151.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1063)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (320, 736, 1165)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2855)
[M::mem_pestat] mean and std.dev: (711.16, 554.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3700)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 332, 759)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1895)
[M::mem_pestat] mean and std.dev: (350.53, 229.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2463)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 693566 sequences (100000017 bp) in 2.703 CPU sec, 2.826 real sec...
[M::process] read 693290 sequences (100000283 bp) in 1.919 CPU sec, 1.927 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 283294, 23, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (128, 198, 529)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1331)
[M::mem_pestat] mean and std.dev: (275.07, 255.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1732)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 273, 399)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 847)
[M::mem_pestat] mean and std.dev: (298.27, 152.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1071)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (531, 1386, 5303)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 14847)
[M::mem_pestat] mean and std.dev: (2364.57, 2107.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 19619)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 326, 600)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1458)
[M::mem_pestat] mean and std.dev: (384.52, 276.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1887)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 694186 reads in 196.730 CPU sec, 6.253 real sec
[M::mem_process_seqs] Processed 694074 reads in 132.502 CPU sec, 4.211 real sec
sorting block 117, #reads = 1072800 mem = 536878868 peak = 1098113024
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 282850, 22, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 271, 408)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 858)
[M::mem_pestat] mean and std.dev: (294.52, 164.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1083)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 274, 400)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 846)
[M::mem_pestat] mean and std.dev: (299.41, 152.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1069)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (880, 1095, 1965)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4135)
[M::mem_pestat] mean and std.dev: (1105.24, 602.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5220)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 358, 513)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1105)
[M::mem_pestat] mean and std.dev: (296.06, 120.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1401)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 693132 sequences (100000283 bp) in 2.615 CPU sec, 2.747 real sec...
[M::process] read 692292 sequences (100000143 bp) in 2.027 CPU sec, 2.048 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 282720, 19, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 235, 993)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2643)
[M::mem_pestat] mean and std.dev: (597.88, 697.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3468)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 274, 402)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 852)
[M::mem_pestat] mean and std.dev: (300.29, 153.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1077)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1178, 1928, 5561)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 14327)
[M::mem_pestat] mean and std.dev: (3274.53, 2451.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 18710)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (322, 474, 910)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2086)
[M::mem_pestat] mean and std.dev: (557.28, 392.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2674)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 693566 reads in 200.541 CPU sec, 6.463 real sec
[M::mem_process_seqs] Processed 693290 reads in 135.143 CPU sec, 4.307 real sec
sorting block 118, #reads = 1073360 mem = 536881187 peak = 1098113024
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 282642, 12, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 296, 391)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 789)
[M::mem_pestat] mean and std.dev: (276.71, 113.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 988)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 277, 405)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 859)
[M::mem_pestat] mean and std.dev: (302.77, 154.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1086)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (311, 674, 1418)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3632)
[M::mem_pestat] mean and std.dev: (902.08, 786.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4739)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 288, 388)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 780)
[M::mem_pestat] mean and std.dev: (287.00, 100.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 976)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 692104 sequences (100000180 bp) in 2.337 CPU sec, 2.437 real sec...
[M::process] read 691558 sequences (100000026 bp) in 1.997 CPU sec, 2.001 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 282016, 27, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (145, 334, 585)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1465)
[M::mem_pestat] mean and std.dev: (308.36, 227.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1905)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 280, 409)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 867)
[M::mem_pestat] mean and std.dev: (305.15, 154.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1096)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (88, 804, 2488)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7288)
[M::mem_pestat] mean and std.dev: (1469.41, 1526.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9688)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (315, 532, 621)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1233)
[M::mem_pestat] mean and std.dev: (463.11, 281.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1591)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 693132 reads in 198.486 CPU sec, 6.320 real sec
sorting block 119, #reads = 1072615 mem = 536880239 peak = 1098113024
[M::mem_process_seqs] Processed 692292 reads in 139.953 CPU sec, 4.471 real sec
sorting block 120, #reads = 1070401 mem = 536881359 peak = 1098113024
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 281736, 18, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (246, 309, 749)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1755)
[M::mem_pestat] mean and std.dev: (434.00, 379.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2258)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 280, 408)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 864)
[M::mem_pestat] mean and std.dev: (305.57, 155.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1092)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (371, 860, 3314)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9200)
[M::mem_pestat] mean and std.dev: (1635.39, 1625.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12143)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 327, 554)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1204)
[M::mem_pestat] mean and std.dev: (366.82, 200.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1529)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 691746 sequences (100000062 bp) in 2.520 CPU sec, 2.625 real sec...
[M::process] read 691804 sequences (100000009 bp) in 1.893 CPU sec, 1.896 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 281302, 13, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 402, 816)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2106)
[M::mem_pestat] mean and std.dev: (495.27, 473.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2751)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 281, 409)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 865)
[M::mem_pestat] mean and std.dev: (306.47, 155.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1093)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (628, 1178, 2622)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6610)
[M::mem_pestat] mean and std.dev: (1348.92, 1050.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8604)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 286, 395)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 771)
[M::mem_pestat] mean and std.dev: (275.24, 101.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 959)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 692104 reads in 201.141 CPU sec, 6.398 real sec
[M::process] read 691214 sequences (100000162 bp) in 2.071 CPU sec, 2.086 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 281698, 18, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 308, 890)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2230)
[M::mem_pestat] mean and std.dev: (487.32, 495.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2900)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 280, 409)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 865)
[M::mem_pestat] mean and std.dev: (306.00, 155.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1093)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 578, 1076)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2922)
[M::mem_pestat] mean and std.dev: (496.69, 402.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3845)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 345, 619)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1443)
[M::mem_pestat] mean and std.dev: (381.44, 243.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1855)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 691746 reads in 113.408 CPU sec, 3.600 real sec
sorting block 121, #reads = 1070860 mem = 536876536 peak = 1098113024
[M::mem_process_seqs] Processed 691558 reads in 290.848 CPU sec, 9.267 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 281618, 28, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 382, 533)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1163)
[M::mem_pestat] mean and std.dev: (386.44, 226.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1478)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 280, 408)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 864)
[M::mem_pestat] mean and std.dev: (305.74, 155.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1092)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (273, 1011, 1945)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5289)
[M::mem_pestat] mean and std.dev: (1213.89, 1193.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6961)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 245, 401)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 849)
[M::mem_pestat] mean and std.dev: (271.27, 152.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1073)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 122, #reads = 1071011 mem = 536877576 peak = 1098113024
[M::process] read 690950 sequences (100000029 bp) in 2.680 CPU sec, 2.816 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 281163, 17, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 572, 847)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2193)
[M::mem_pestat] mean and std.dev: (570.95, 492.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2866)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 281, 410)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 866)
[M::mem_pestat] mean and std.dev: (307.13, 155.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1094)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (420, 601, 1090)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2430)
[M::mem_pestat] mean and std.dev: (591.40, 328.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3100)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (285, 398, 785)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1785)
[M::mem_pestat] mean and std.dev: (502.33, 369.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2285)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 690786 sequences (100000043 bp) in 1.634 CPU sec, 1.641 real sec...
[M::mem_process_seqs] Processed 691804 reads in 224.128 CPU sec, 7.134 real sec
[M::mem_process_seqs] Processed 691214 reads in 137.930 CPU sec, 4.646 real sec
sorting block 123, #reads = 1069960 mem = 536879357 peak = 1098113024
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 281323, 30, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 260, 450)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 958)
[M::mem_pestat] mean and std.dev: (270.45, 118.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1212)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 283, 411)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 867)
[M::mem_pestat] mean and std.dev: (308.28, 156.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1095)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (304, 484, 680)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1432)
[M::mem_pestat] mean and std.dev: (552.97, 317.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1824)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (284, 384, 899)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2129)
[M::mem_pestat] mean and std.dev: (480.97, 290.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2744)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 690752 sequences (100000293 bp) in 2.829 CPU sec, 3.015 real sec...
[M::process] read 691000 sequences (100000123 bp) in 1.959 CPU sec, 1.960 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 281251, 24, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 250, 418)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 884)
[M::mem_pestat] mean and std.dev: (290.07, 176.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1117)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 284, 411)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 867)
[M::mem_pestat] mean and std.dev: (308.00, 155.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1095)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (302, 727, 2381)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6539)
[M::mem_pestat] mean and std.dev: (1372.79, 1617.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8618)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (238, 356, 629)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1411)
[M::mem_pestat] mean and std.dev: (419.78, 316.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1802)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 690950 reads in 201.665 CPU sec, 6.677 real sec
[M::mem_process_seqs] Processed 690786 reads in 137.562 CPU sec, 4.372 real sec
sorting block 124, #reads = 1071126 mem = 536879101 peak = 1098113024
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 281909, 25, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 357, 906)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2392)
[M::mem_pestat] mean and std.dev: (510.02, 546.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3135)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 284, 412)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 870)
[M::mem_pestat] mean and std.dev: (309.13, 156.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1099)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (72, 488, 650)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1806)
[M::mem_pestat] mean and std.dev: (431.68, 313.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2384)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 311, 599)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1387)
[M::mem_pestat] mean and std.dev: (385.31, 253.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1781)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 691018 sequences (100000076 bp) in 2.660 CPU sec, 2.787 real sec...
[M::process] read 690580 sequences (100000255 bp) in 1.854 CPU sec, 1.860 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 281613, 12, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 377, 832)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2166)
[M::mem_pestat] mean and std.dev: (388.70, 288.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2833)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 282, 413)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 875)
[M::mem_pestat] mean and std.dev: (308.80, 157.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1106)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (593, 606, 2049)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4961)
[M::mem_pestat] mean and std.dev: (757.60, 595.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6417)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 518, 754)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1820)
[M::mem_pestat] mean and std.dev: (429.16, 298.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2353)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 690752 reads in 189.489 CPU sec, 6.020 real sec
sorting block 125, #reads = 1071139 mem = 536880761 peak = 1098113024
[M::mem_process_seqs] Processed 691000 reads in 124.092 CPU sec, 3.938 real sec
sorting block 126, #reads = 1071768 mem = 536878191 peak = 1098113024
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 281863, 36, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (227, 270, 370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 656)
[M::mem_pestat] mean and std.dev: (295.34, 117.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 799)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 285, 414)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 876)
[M::mem_pestat] mean and std.dev: (309.91, 157.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1107)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (561, 1178, 4914)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13620)
[M::mem_pestat] mean and std.dev: (1996.28, 1980.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17973)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 283, 660)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1546)
[M::mem_pestat] mean and std.dev: (372.29, 274.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1989)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 690354 sequences (100000104 bp) in 2.936 CPU sec, 3.083 real sec...
[M::process] read 690244 sequences (100000082 bp) in 1.946 CPU sec, 1.945 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 280908, 12, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 326, 499)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1073)
[M::mem_pestat] mean and std.dev: (317.80, 180.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1360)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 285, 416)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 882)
[M::mem_pestat] mean and std.dev: (311.52, 159.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1115)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (615, 677, 758)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (329, 1044)
[M::mem_pestat] mean and std.dev: (627.56, 113.83)
[M::mem_pestat] low and high boundaries for proper pairs: (172, 1187)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (241, 409, 637)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1429)
[M::mem_pestat] mean and std.dev: (387.77, 236.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1825)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 691018 reads in 190.727 CPU sec, 6.049 real sec
[M::mem_process_seqs] Processed 690580 reads in 129.832 CPU sec, 4.121 real sec
sorting block 127, #reads = 1072699 mem = 536877120 peak = 1098113024
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 281619, 23, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 352, 466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 998)
[M::mem_pestat] mean and std.dev: (357.27, 209.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1264)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 286, 419)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 889)
[M::mem_pestat] mean and std.dev: (313.06, 160.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1124)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (424, 1473, 4330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12142)
[M::mem_pestat] mean and std.dev: (1798.22, 1797.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 16048)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (282, 389, 824)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1908)
[M::mem_pestat] mean and std.dev: (506.84, 415.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2450)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 690444 sequences (100000100 bp) in 2.746 CPU sec, 2.897 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 281419, 22, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 330, 709)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1683)
[M::mem_pestat] mean and std.dev: (442.68, 373.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2170)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 287, 420)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 892)
[M::mem_pestat] mean and std.dev: (313.98, 161.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1128)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (63, 394, 892)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2550)
[M::mem_pestat] mean and std.dev: (569.95, 509.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3379)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (291, 370, 1079)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2655)
[M::mem_pestat] mean and std.dev: (528.93, 409.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3443)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 691148 sequences (100000101 bp) in 2.041 CPU sec, 2.050 real sec...
[M::mem_process_seqs] Processed 690354 reads in 193.893 CPU sec, 6.169 real sec
[M::process] read 698568 sequences (100000217 bp) in 2.234 CPU sec, 2.251 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 281344, 16, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (245, 369, 874)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2132)
[M::mem_pestat] mean and std.dev: (428.84, 369.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2761)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 287, 420)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 892)
[M::mem_pestat] mean and std.dev: (314.08, 161.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1128)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (234, 258, 762)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1818)
[M::mem_pestat] mean and std.dev: (419.80, 317.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2346)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 250, 492)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1146)
[M::mem_pestat] mean and std.dev: (287.98, 179.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1473)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 690444 reads in 115.141 CPU sec, 3.955 real sec
sorting block 128, #reads = 1070869 mem = 536880680 peak = 1098113024
[M::mem_process_seqs] Processed 690244 reads in 283.473 CPU sec, 9.324 real sec
sorting block 129, #reads = 1069614 mem = 536882073 peak = 1098113024
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 281260, 13, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 310, 601)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1391)
[M::mem_pestat] mean and std.dev: (373.12, 242.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1786)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 282, 417)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 887)
[M::mem_pestat] mean and std.dev: (311.29, 162.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1122)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (245, 485, 1262)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3296)
[M::mem_pestat] mean and std.dev: (739.08, 657.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4313)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 263, 407)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 849)
[M::mem_pestat] mean and std.dev: (254.08, 124.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1070)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697706 sequences (100000028 bp) in 2.589 CPU sec, 2.913 real sec...
[M::process] read 696802 sequences (100000018 bp) in 1.683 CPU sec, 1.688 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 284420, 16, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 352, 598)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1382)
[M::mem_pestat] mean and std.dev: (373.62, 279.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1774)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 254, 378)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 802)
[M::mem_pestat] mean and std.dev: (283.61, 148.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1014)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (630, 804, 1853)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4299)
[M::mem_pestat] mean and std.dev: (1147.50, 852.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5522)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 318, 553)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1335)
[M::mem_pestat] mean and std.dev: (372.45, 271.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1726)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 691148 reads in 235.818 CPU sec, 7.519 real sec
[M::mem_process_seqs] Processed 698568 reads in 148.526 CPU sec, 4.727 real sec
sorting block 130, #reads = 1062948 mem = 536879851 peak = 1098113024
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 283578, 26, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 305, 570)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1312)
[M::mem_pestat] mean and std.dev: (371.16, 292.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1683)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 257, 380)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 806)
[M::mem_pestat] mean and std.dev: (285.35, 148.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1019)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (348, 836, 1132)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2700)
[M::mem_pestat] mean and std.dev: (893.16, 709.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3732)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 286, 542)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1296)
[M::mem_pestat] mean and std.dev: (333.86, 240.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1673)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695578 sequences (100000071 bp) in 2.630 CPU sec, 3.099 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 283456, 22, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 224, 523)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1211)
[M::mem_pestat] mean and std.dev: (361.25, 287.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1555)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 260, 382)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 808)
[M::mem_pestat] mean and std.dev: (287.51, 147.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1021)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 953, 1211)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3197)
[M::mem_pestat] mean and std.dev: (723.68, 693.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4190)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 272, 951)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2511)
[M::mem_pestat] mean and std.dev: (505.79, 561.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3291)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694848 sequences (100000138 bp) in 1.920 CPU sec, 1.911 real sec...
[M::mem_process_seqs] Processed 697706 reads in 170.117 CPU sec, 5.373 real sec
sorting block 131, #reads = 1072508 mem = 536881119 peak = 1098113024
[M::mem_process_seqs] Processed 696802 reads in 114.235 CPU sec, 3.615 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 283451, 16, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 241, 382)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 850)
[M::mem_pestat] mean and std.dev: (218.46, 93.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1084)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 265, 387)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 817)
[M::mem_pestat] mean and std.dev: (290.67, 147.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1032)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (327, 632, 897)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2037)
[M::mem_pestat] mean and std.dev: (559.93, 466.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2607)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 226, 473)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1097)
[M::mem_pestat] mean and std.dev: (265.38, 177.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1409)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694724 sequences (100000270 bp) in 2.614 CPU sec, 2.732 real sec...
[M::process] read 694506 sequences (100000144 bp) in 1.869 CPU sec, 1.878 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 283438, 15, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (227, 425, 1053)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2705)
[M::mem_pestat] mean and std.dev: (432.67, 322.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3531)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 267, 391)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 827)
[M::mem_pestat] mean and std.dev: (293.32, 149.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1045)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (409, 818, 2028)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5266)
[M::mem_pestat] mean and std.dev: (1219.20, 1056.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6885)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (262, 379, 1192)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3052)
[M::mem_pestat] mean and std.dev: (648.99, 550.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3982)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695578 reads in 184.489 CPU sec, 6.098 real sec
sorting block 132, #reads = 1076099 mem = 536878508 peak = 1098113024
[M::mem_process_seqs] Processed 694848 reads in 124.604 CPU sec, 3.953 real sec
sorting block 133, #reads = 1076667 mem = 536881658 peak = 1098113024
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 283901, 6, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 309, 703)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1719)
[M::mem_pestat] mean and std.dev: (433.81, 379.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2227)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 268, 392)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 828)
[M::mem_pestat] mean and std.dev: (293.65, 149.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1046)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 283, 825)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2083)
[M::mem_pestat] mean and std.dev: (357.34, 251.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2712)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 694196 sequences (100000112 bp) in 2.604 CPU sec, 2.744 real sec...
[M::process] read 693240 sequences (100000229 bp) in 1.814 CPU sec, 1.818 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 282955, 17, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (140, 224, 282)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 566)
[M::mem_pestat] mean and std.dev: (203.05, 85.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 708)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 269, 393)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 831)
[M::mem_pestat] mean and std.dev: (294.57, 149.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1050)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 1279, 2393)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6803)
[M::mem_pestat] mean and std.dev: (1294.27, 1415.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9008)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (142, 222, 475)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1141)
[M::mem_pestat] mean and std.dev: (285.31, 191.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1474)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 694724 reads in 188.496 CPU sec, 5.996 real sec
[M::mem_process_seqs] Processed 694506 reads in 123.651 CPU sec, 3.924 real sec
sorting block 134, #reads = 1075936 mem = 536880934 peak = 1098113024
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 283759, 14, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 387, 962)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2486)
[M::mem_pestat] mean and std.dev: (715.00, 698.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3507)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 270, 396)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 838)
[M::mem_pestat] mean and std.dev: (296.53, 150.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1059)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (236, 562, 1070)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2738)
[M::mem_pestat] mean and std.dev: (449.09, 311.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3572)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 465, 674)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1584)
[M::mem_pestat] mean and std.dev: (496.64, 305.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2039)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 693188 sequences (100000041 bp) in 2.627 CPU sec, 2.759 real sec...
[M::process] read 693334 sequences (100000120 bp) in 1.870 CPU sec, 1.869 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 282772, 12, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 309, 576)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1402)
[M::mem_pestat] mean and std.dev: (365.48, 290.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1815)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 274, 399)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 843)
[M::mem_pestat] mean and std.dev: (299.34, 152.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1065)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (406, 1629, 3300)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9088)
[M::mem_pestat] mean and std.dev: (1684.09, 1631.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11982)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 336, 511)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1115)
[M::mem_pestat] mean and std.dev: (324.27, 166.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1417)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 694196 reads in 180.005 CPU sec, 5.728 real sec
[M::mem_process_seqs] Processed 693240 reads in 120.140 CPU sec, 4.072 real sec
sorting block 135, #reads = 1074972 mem = 536877897 peak = 1098113024
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 282994, 20, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 269, 597)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1399)
[M::mem_pestat] mean and std.dev: (327.63, 298.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1800)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 275, 402)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 854)
[M::mem_pestat] mean and std.dev: (300.34, 152.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1080)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 1500, 8805)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 25979)
[M::mem_pestat] mean and std.dev: (3428.25, 3740.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 34566)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 240, 830)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2154)
[M::mem_pestat] mean and std.dev: (453.89, 466.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2816)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 693006 sequences (100000218 bp) in 2.524 CPU sec, 2.641 real sec...
[M::process] read 693242 sequences (100000213 bp) in 1.960 CPU sec, 1.956 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 283321, 10, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 314, 526)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1220)
[M::mem_pestat] mean and std.dev: (352.71, 199.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1567)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 275, 404)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 858)
[M::mem_pestat] mean and std.dev: (301.40, 154.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1085)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (590, 2623, 2623)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6689)
[M::mem_pestat] mean and std.dev: (1909.50, 1103.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8722)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (254, 369, 1172)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3008)
[M::mem_pestat] mean and std.dev: (655.80, 577.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3926)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 693188 reads in 192.803 CPU sec, 6.374 real sec
sorting block 136, #reads = 1076630 mem = 536883151 peak = 1098113024
[M::mem_process_seqs] Processed 693334 reads in 126.955 CPU sec, 4.028 real sec
sorting block 137, #reads = 1075832 mem = 536879431 peak = 1098113024
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 283052, 29, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 351, 411)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 873)
[M::mem_pestat] mean and std.dev: (279.36, 126.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1104)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 276, 405)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 859)
[M::mem_pestat] mean and std.dev: (302.14, 153.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1086)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (266, 396, 1445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3803)
[M::mem_pestat] mean and std.dev: (718.38, 636.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4982)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 273, 839)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2161)
[M::mem_pestat] mean and std.dev: (483.14, 389.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2822)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 692930 sequences (100000067 bp) in 2.435 CPU sec, 2.538 real sec...
[M::process] read 692664 sequences (100000137 bp) in 1.999 CPU sec, 2.002 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 282994, 7, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (139, 296, 428)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1006)
[M::mem_pestat] mean and std.dev: (267.86, 127.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1295)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 276, 402)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 852)
[M::mem_pestat] mean and std.dev: (300.56, 152.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1077)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (259, 464, 1036)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2590)
[M::mem_pestat] mean and std.dev: (583.80, 491.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3367)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 693006 reads in 186.143 CPU sec, 5.910 real sec
[M::mem_process_seqs] Processed 693242 reads in 125.047 CPU sec, 3.969 real sec
sorting block 138, #reads = 1074101 mem = 536878927 peak = 1098113024
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 282615, 11, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 255, 561)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1337)
[M::mem_pestat] mean and std.dev: (331.54, 222.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1725)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 278, 405)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 859)
[M::mem_pestat] mean and std.dev: (302.87, 153.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1086)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (664, 818, 894)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (204, 1354)
[M::mem_pestat] mean and std.dev: (766.43, 117.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1584)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (271, 392, 922)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2224)
[M::mem_pestat] mean and std.dev: (541.50, 394.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2875)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 692006 sequences (100000029 bp) in 2.600 CPU sec, 2.720 real sec...
[M::process] read 691872 sequences (100000112 bp) in 1.860 CPU sec, 1.853 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 282563, 19, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (316, 425, 611)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1201)
[M::mem_pestat] mean and std.dev: (401.31, 230.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1496)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 279, 408)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 866)
[M::mem_pestat] mean and std.dev: (304.42, 154.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1095)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (399, 765, 1863)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4791)
[M::mem_pestat] mean and std.dev: (1064.11, 874.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6255)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (278, 322, 516)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 992)
[M::mem_pestat] mean and std.dev: (325.07, 133.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1230)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 692930 reads in 182.724 CPU sec, 5.839 real sec
[M::mem_process_seqs] Processed 692664 reads in 120.387 CPU sec, 3.809 real sec
sorting block 139, #reads = 1075104 mem = 536878331 peak = 1098113024
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 282573, 13, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 298, 476)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1056)
[M::mem_pestat] mean and std.dev: (315.16, 203.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1346)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 281, 409)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 867)
[M::mem_pestat] mean and std.dev: (305.03, 154.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1096)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (136, 681, 1629)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4615)
[M::mem_pestat] mean and std.dev: (797.62, 710.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6108)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 327, 936)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2468)
[M::mem_pestat] mean and std.dev: (510.49, 467.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3234)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 690884 sequences (100000100 bp) in 2.698 CPU sec, 2.808 real sec...
[M::process] read 690856 sequences (100000238 bp) in 2.010 CPU sec, 2.008 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 282620, 7, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 308, 916)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2392)
[M::mem_pestat] mean and std.dev: (522.21, 461.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3130)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 282, 410)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 868)
[M::mem_pestat] mean and std.dev: (306.15, 154.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1097)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 252, 519)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1181)
[M::mem_pestat] mean and std.dev: (329.84, 254.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1512)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 692006 reads in 189.096 CPU sec, 6.093 real sec
sorting block 140, #reads = 1074071 mem = 536878539 peak = 1098113024
[M::mem_process_seqs] Processed 691872 reads in 125.468 CPU sec, 3.976 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 281778, 25, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 341, 916)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2354)
[M::mem_pestat] mean and std.dev: (585.30, 626.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3091)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 285, 411)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 867)
[M::mem_pestat] mean and std.dev: (308.54, 154.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1095)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (869, 1301, 3285)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8117)
[M::mem_pestat] mean and std.dev: (2068.60, 1804.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10533)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (140, 229, 286)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 578)
[M::mem_pestat] mean and std.dev: (219.13, 97.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 724)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 690864 sequences (100000285 bp) in 2.690 CPU sec, 2.814 real sec...
[M::process] read 690886 sequences (100000212 bp) in 1.610 CPU sec, 1.602 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 281140, 20, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 217, 372)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 782)
[M::mem_pestat] mean and std.dev: (256.31, 131.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 987)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 284, 412)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 870)
[M::mem_pestat] mean and std.dev: (308.16, 154.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1099)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (117, 1007, 1100)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3066)
[M::mem_pestat] mean and std.dev: (806.58, 825.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4108)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 292, 432)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 896)
[M::mem_pestat] mean and std.dev: (311.52, 167.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1128)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 690884 reads in 191.547 CPU sec, 6.182 real sec
sorting block 141, #reads = 1072281 mem = 536878562 peak = 1098113024
[M::mem_process_seqs] Processed 690856 reads in 124.666 CPU sec, 3.960 real sec
sorting block 142, #reads = 1070808 mem = 536880858 peak = 1098113024
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 281058, 13, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 365, 1417)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3835)
[M::mem_pestat] mean and std.dev: (749.48, 728.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5044)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 284, 411)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 867)
[M::mem_pestat] mean and std.dev: (307.56, 154.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1095)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 647, 1149)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3031)
[M::mem_pestat] mean and std.dev: (740.69, 645.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3972)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 319, 519)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1153)
[M::mem_pestat] mean and std.dev: (346.25, 183.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1470)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 690982 sequences (100000044 bp) in 2.774 CPU sec, 2.873 real sec...
[M::process] read 690808 sequences (100000111 bp) in 1.792 CPU sec, 1.789 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 281496, 17, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 247, 440)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 970)
[M::mem_pestat] mean and std.dev: (278.81, 145.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1235)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 283, 409)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 861)
[M::mem_pestat] mean and std.dev: (307.10, 154.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1087)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (695, 892, 2677)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6641)
[M::mem_pestat] mean and std.dev: (1129.27, 1010.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8623)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 317, 405)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 801)
[M::mem_pestat] mean and std.dev: (294.64, 127.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 999)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 690864 reads in 183.981 CPU sec, 5.833 real sec
[M::mem_process_seqs] Processed 690886 reads in 117.100 CPU sec, 3.715 real sec
sorting block 143, #reads = 1071226 mem = 536876123 peak = 1098113024
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 281597, 19, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 290, 599)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1379)
[M::mem_pestat] mean and std.dev: (405.16, 289.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1769)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 283, 409)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 861)
[M::mem_pestat] mean and std.dev: (307.21, 154.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1087)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (357, 520, 1298)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3180)
[M::mem_pestat] mean and std.dev: (749.17, 610.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4121)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (255, 461, 818)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1944)
[M::mem_pestat] mean and std.dev: (522.55, 392.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2507)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 691056 sequences (100000218 bp) in 2.559 CPU sec, 2.660 real sec...
[M::process] read 691192 sequences (100000239 bp) in 1.450 CPU sec, 1.445 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 281816, 25, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 461, 860)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2222)
[M::mem_pestat] mean and std.dev: (456.58, 363.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2903)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 283, 409)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 861)
[M::mem_pestat] mean and std.dev: (307.15, 154.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1087)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (450, 960, 1920)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4860)
[M::mem_pestat] mean and std.dev: (984.95, 804.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6330)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 375, 1517)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4119)
[M::mem_pestat] mean and std.dev: (904.81, 920.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5420)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 690982 reads in 161.941 CPU sec, 5.139 real sec
[M::mem_process_seqs] Processed 690808 reads in 109.251 CPU sec, 3.468 real sec
sorting block 144, #reads = 1070484 mem = 536884771 peak = 1098113024
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 281580, 24, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 315, 847)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2197)
[M::mem_pestat] mean and std.dev: (497.57, 503.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2872)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 281, 409)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 863)
[M::mem_pestat] mean and std.dev: (306.65, 155.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1090)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (396, 429, 2349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6255)
[M::mem_pestat] mean and std.dev: (807.71, 760.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8208)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 285, 646)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1570)
[M::mem_pestat] mean and std.dev: (403.83, 336.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2032)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 690838 sequences (100000191 bp) in 2.298 CPU sec, 2.379 real sec...
[M::process] read 690812 sequences (100000165 bp) in 1.470 CPU sec, 1.470 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 281720, 21, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 300, 502)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1114)
[M::mem_pestat] mean and std.dev: (271.44, 119.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1420)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 281, 407)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 857)
[M::mem_pestat] mean and std.dev: (305.69, 154.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1082)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (879, 1002, 5048)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13386)
[M::mem_pestat] mean and std.dev: (2148.57, 2266.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17555)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 332, 568)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1362)
[M::mem_pestat] mean and std.dev: (399.25, 264.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1759)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 691056 reads in 171.116 CPU sec, 5.437 real sec
sorting block 145, #reads = 1070515 mem = 536884693 peak = 1098113024
[M::mem_process_seqs] Processed 691192 reads in 120.479 CPU sec, 3.840 real sec
sorting block 146, #reads = 1069378 mem = 536878179 peak = 1098113024
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 281154, 13, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (236, 599, 1342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3554)
[M::mem_pestat] mean and std.dev: (665.98, 730.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4660)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 282, 409)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 861)
[M::mem_pestat] mean and std.dev: (307.21, 154.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1087)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (588, 923, 3177)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8355)
[M::mem_pestat] mean and std.dev: (1417.77, 1191.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10944)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (245, 364, 650)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1460)
[M::mem_pestat] mean and std.dev: (470.67, 342.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1865)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 690948 sequences (100000004 bp) in 2.398 CPU sec, 2.512 real sec...
[M::process] read 690840 sequences (100000086 bp) in 1.770 CPU sec, 1.766 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 281404, 23, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (132, 231, 386)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 894)
[M::mem_pestat] mean and std.dev: (296.37, 231.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1223)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 282, 408)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 858)
[M::mem_pestat] mean and std.dev: (306.89, 154.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1083)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (431, 734, 2022)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5204)
[M::mem_pestat] mean and std.dev: (890.32, 643.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6795)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (230, 345, 455)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 905)
[M::mem_pestat] mean and std.dev: (356.52, 174.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1130)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 690838 reads in 178.849 CPU sec, 5.679 real sec
[M::mem_process_seqs] Processed 690812 reads in 115.104 CPU sec, 3.916 real sec
sorting block 147, #reads = 1066874 mem = 536879175 peak = 1098113024
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 281648, 15, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 213, 612)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1510)
[M::mem_pestat] mean and std.dev: (313.92, 229.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1959)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 283, 410)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 864)
[M::mem_pestat] mean and std.dev: (307.76, 155.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1091)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (71, 307, 1004)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2870)
[M::mem_pestat] mean and std.dev: (565.73, 588.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3803)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 355, 480)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1028)
[M::mem_pestat] mean and std.dev: (304.27, 170.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1302)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 691202 sequences (100000211 bp) in 2.688 CPU sec, 2.766 real sec...
[M::process] read 691300 sequences (100000067 bp) in 1.840 CPU sec, 1.843 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 281691, 21, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 277, 390)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 768)
[M::mem_pestat] mean and std.dev: (296.33, 142.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 957)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 282, 412)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 872)
[M::mem_pestat] mean and std.dev: (308.42, 156.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1102)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (529, 773, 4035)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 11047)
[M::mem_pestat] mean and std.dev: (2250.38, 2033.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14553)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (261, 474, 1322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3444)
[M::mem_pestat] mean and std.dev: (633.75, 612.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4505)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 690948 reads in 176.310 CPU sec, 5.846 real sec
[M::mem_process_seqs] Processed 690840 reads in 113.978 CPU sec, 3.612 real sec
sorting block 148, #reads = 1069691 mem = 536878224 peak = 1098113024
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 281268, 12, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 327, 436)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 944)
[M::mem_pestat] mean and std.dev: (291.51, 166.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1198)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 282, 412)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 874)
[M::mem_pestat] mean and std.dev: (307.85, 156.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1105)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (637, 903, 1435)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3031)
[M::mem_pestat] mean and std.dev: (916.17, 486.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3829)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (249, 332, 725)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1677)
[M::mem_pestat] mean and std.dev: (396.66, 322.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2153)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696200 sequences (100000272 bp) in 2.366 CPU sec, 2.428 real sec...
[M::process] read 702554 sequences (100000124 bp) in 1.680 CPU sec, 1.689 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 281309, 21, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 281, 504)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1126)
[M::mem_pestat] mean and std.dev: (278.62, 120.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1437)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 281, 411)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 869)
[M::mem_pestat] mean and std.dev: (307.92, 157.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1098)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (464, 729, 1268)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2876)
[M::mem_pestat] mean and std.dev: (794.84, 566.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3680)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (232, 346, 446)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 874)
[M::mem_pestat] mean and std.dev: (329.20, 139.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1088)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 691202 reads in 183.868 CPU sec, 5.936 real sec
sorting block 149, #reads = 1068621 mem = 536880626 peak = 1098113024
[M::mem_process_seqs] Processed 691300 reads in 127.870 CPU sec, 4.063 real sec
sorting block 150, #reads = 1064412 mem = 536884317 peak = 1098113024
[M::process] read 699956 sequences (100000114 bp) in 2.627 CPU sec, 2.709 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 286165, 19, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 290, 439)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1017)
[M::mem_pestat] mean and std.dev: (311.26, 201.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1306)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 239, 356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 750)
[M::mem_pestat] mean and std.dev: (268.71, 139.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 947)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (448, 731, 1612)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3940)
[M::mem_pestat] mean and std.dev: (943.00, 811.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5104)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (232, 372, 1202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3142)
[M::mem_pestat] mean and std.dev: (716.71, 672.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4112)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698938 sequences (100000280 bp) in 1.979 CPU sec, 1.972 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 282562, 21, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 255, 455)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1053)
[M::mem_pestat] mean and std.dev: (258.13, 139.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1352)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 261, 388)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 824)
[M::mem_pestat] mean and std.dev: (290.81, 151.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1042)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (677, 745, 1076)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1874)
[M::mem_pestat] mean and std.dev: (795.15, 358.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2273)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 341, 518)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1106)
[M::mem_pestat] mean and std.dev: (351.52, 195.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1400)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702554 reads in 188.994 CPU sec, 5.986 real sec
[M::mem_process_seqs] Processed 696200 reads in 216.953 CPU sec, 6.894 real sec
sorting block 151, #reads = 1068614 mem = 536881617 peak = 1098113024
[M::process] read 698116 sequences (100000159 bp) in 2.175 CPU sec, 2.260 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 285273, 19, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 185, 794)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2086)
[M::mem_pestat] mean and std.dev: (316.92, 295.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2732)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 248, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 775)
[M::mem_pestat] mean and std.dev: (276.41, 142.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 979)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (550, 1133, 4004)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10912)
[M::mem_pestat] mean and std.dev: (1943.53, 1634.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14366)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 239, 345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 697)
[M::mem_pestat] mean and std.dev: (234.64, 100.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 873)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697320 sequences (100000265 bp) in 1.930 CPU sec, 1.935 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 284865, 32, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 260, 605)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1453)
[M::mem_pestat] mean and std.dev: (355.57, 322.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1877)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 255, 377)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 799)
[M::mem_pestat] mean and std.dev: (282.75, 145.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1010)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (320, 725, 1222)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3026)
[M::mem_pestat] mean and std.dev: (827.88, 745.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3928)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 281, 352)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 692)
[M::mem_pestat] mean and std.dev: (264.47, 125.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 862)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 284714, 18, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (260, 346, 687)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1541)
[M::mem_pestat] mean and std.dev: (401.90, 245.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1968)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 251, 373)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 791)
[M::mem_pestat] mean and std.dev: (279.60, 144.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1000)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (545, 953, 1865)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4505)
[M::mem_pestat] mean and std.dev: (1146.19, 1014.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5825)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (258, 329, 471)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 897)
[M::mem_pestat] mean and std.dev: (319.33, 116.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1110)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699956 reads in 246.027 CPU sec, 7.836 real sec
[M::mem_process_seqs] Processed 698116 reads in 184.671 CPU sec, 5.903 real sec
sorting block 152, #reads = 1067894 mem = 536883162 peak = 1098113024
[M::mem_process_seqs] Processed 698938 reads in 204.528 CPU sec, 6.551 real sec
[M::process] read 698814 sequences (100000199 bp) in 2.584 CPU sec, 2.720 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 283897, 7, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 330, 499)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1087)
[M::mem_pestat] mean and std.dev: (344.26, 203.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1381)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 258, 381)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 807)
[M::mem_pestat] mean and std.dev: (285.51, 146.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1020)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 481, 1271)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3367)
[M::mem_pestat] mean and std.dev: (683.37, 570.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4415)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 153, #reads = 1073595 mem = 536877624 peak = 1098113024
[M::process] read 699682 sequences (100000019 bp) in 2.194 CPU sec, 2.274 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 284826, 16, 73)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 349, 387)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 779)
[M::mem_pestat] mean and std.dev: (282.27, 139.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 975)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 251, 371)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 783)
[M::mem_pestat] mean and std.dev: (279.07, 143.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 989)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (278, 501, 975)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2369)
[M::mem_pestat] mean and std.dev: (561.07, 478.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3066)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (243, 406, 912)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2250)
[M::mem_pestat] mean and std.dev: (576.03, 497.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2919)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697320 reads in 172.622 CPU sec, 5.517 real sec
[M::mem_process_seqs] Processed 698814 reads in 116.433 CPU sec, 3.678 real sec
sorting block 154, #reads = 1072509 mem = 536877746 peak = 1098113024
[M::process] read 697166 sequences (100000274 bp) in 2.528 CPU sec, 2.661 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 285186, 20, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 314, 821)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2077)
[M::mem_pestat] mean and std.dev: (412.70, 403.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2705)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 249, 370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 784)
[M::mem_pestat] mean and std.dev: (277.67, 143.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 991)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (45, 236, 411)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1143)
[M::mem_pestat] mean and std.dev: (249.33, 213.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1509)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 325, 509)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1117)
[M::mem_pestat] mean and std.dev: (325.03, 174.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1421)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696998 sequences (100000043 bp) in 2.279 CPU sec, 2.351 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 284574, 17, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 319, 596)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1410)
[M::mem_pestat] mean and std.dev: (378.53, 245.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1817)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 257, 382)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 810)
[M::mem_pestat] mean and std.dev: (285.98, 147.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1024)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (244, 487, 790)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1882)
[M::mem_pestat] mean and std.dev: (548.18, 439.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2428)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 278, 463)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 989)
[M::mem_pestat] mean and std.dev: (327.31, 198.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1252)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696846 sequences (100000121 bp) in 1.840 CPU sec, 1.839 real sec...
[M::mem_process_seqs] Processed 699682 reads in 178.595 CPU sec, 5.669 real sec
sorting block 155, #reads = 1072167 mem = 536882672 peak = 1098113024
[M::mem_process_seqs] Processed 697166 reads in 115.817 CPU sec, 3.934 real sec
sorting block 156, #reads = 1070944 mem = 536888151 peak = 1098113024
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 284490, 9, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 215, 354)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 718)
[M::mem_pestat] mean and std.dev: (242.71, 123.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 900)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 257, 382)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 810)
[M::mem_pestat] mean and std.dev: (285.90, 147.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1024)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 303, 450)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 966)
[M::mem_pestat] mean and std.dev: (298.29, 147.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1224)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 694896 sequences (100000146 bp) in 2.563 CPU sec, 2.706 real sec...
[M::process] read 695562 sequences (100000218 bp) in 1.910 CPU sec, 1.909 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 283735, 21, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 236, 552)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1280)
[M::mem_pestat] mean and std.dev: (271.45, 161.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1644)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 257, 382)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 808)
[M::mem_pestat] mean and std.dev: (286.68, 148.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1021)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (465, 813, 1818)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4524)
[M::mem_pestat] mean and std.dev: (1209.62, 980.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5877)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (238, 343, 925)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2299)
[M::mem_pestat] mean and std.dev: (537.02, 498.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2986)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696998 reads in 170.301 CPU sec, 5.642 real sec
[M::mem_process_seqs] Processed 696846 reads in 110.568 CPU sec, 3.572 real sec
sorting block 157, #reads = 1073244 mem = 536887487 peak = 1098113024
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 282794, 17, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 309, 465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 997)
[M::mem_pestat] mean and std.dev: (315.47, 151.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1263)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 266, 394)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 838)
[M::mem_pestat] mean and std.dev: (293.94, 151.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1060)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (404, 988, 2385)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6347)
[M::mem_pestat] mean and std.dev: (1410.24, 1178.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8328)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (258, 351, 519)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1041)
[M::mem_pestat] mean and std.dev: (357.50, 166.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1302)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694174 sequences (100000152 bp) in 2.402 CPU sec, 2.514 real sec...
[M::process] read 693674 sequences (100000111 bp) in 1.480 CPU sec, 1.474 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 283293, 17, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 233, 422)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 908)
[M::mem_pestat] mean and std.dev: (238.03, 127.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1151)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 265, 393)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 837)
[M::mem_pestat] mean and std.dev: (293.25, 150.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1059)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 512, 5007)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 14711)
[M::mem_pestat] mean and std.dev: (1735.71, 1971.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 19563)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 324, 388)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 746)
[M::mem_pestat] mean and std.dev: (285.46, 103.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 925)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 694896 reads in 170.891 CPU sec, 5.496 real sec
[M::mem_process_seqs] Processed 695562 reads in 109.952 CPU sec, 3.495 real sec
sorting block 158, #reads = 1071565 mem = 536880308 peak = 1098113024
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 282482, 25, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 232, 673)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1643)
[M::mem_pestat] mean and std.dev: (422.15, 395.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2128)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 270, 401)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 853)
[M::mem_pestat] mean and std.dev: (298.34, 153.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1079)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 505, 2076)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5916)
[M::mem_pestat] mean and std.dev: (1238.16, 1444.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7836)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (241, 387, 753)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1777)
[M::mem_pestat] mean and std.dev: (541.18, 410.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2289)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 692674 sequences (100000271 bp) in 2.389 CPU sec, 2.504 real sec...
[M::process] read 692206 sequences (100000097 bp) in 1.700 CPU sec, 1.698 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 283105, 22, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 297, 596)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1362)
[M::mem_pestat] mean and std.dev: (342.16, 244.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1745)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 274, 405)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 863)
[M::mem_pestat] mean and std.dev: (301.32, 154.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1092)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 731, 1756)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4910)
[M::mem_pestat] mean and std.dev: (819.59, 752.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6487)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (141, 293, 421)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 981)
[M::mem_pestat] mean and std.dev: (259.22, 126.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1261)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 694174 reads in 168.113 CPU sec, 5.335 real sec
[M::mem_process_seqs] Processed 693674 reads in 108.829 CPU sec, 3.454 real sec
sorting block 159, #reads = 1069931 mem = 536881029 peak = 1098113024
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 282256, 21, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (233, 332, 768)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1838)
[M::mem_pestat] mean and std.dev: (512.02, 433.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2373)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 276, 405)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 859)
[M::mem_pestat] mean and std.dev: (302.58, 154.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1086)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (119, 490, 868)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2366)
[M::mem_pestat] mean and std.dev: (367.89, 312.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3115)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 300, 478)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1018)
[M::mem_pestat] mean and std.dev: (327.96, 179.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1288)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 691726 sequences (100000298 bp) in 2.538 CPU sec, 2.645 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 281860, 14, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (272, 360, 1217)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3107)
[M::mem_pestat] mean and std.dev: (518.91, 391.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4052)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 278, 406)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 860)
[M::mem_pestat] mean and std.dev: (303.18, 153.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1087)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (364, 672, 992)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2248)
[M::mem_pestat] mean and std.dev: (602.92, 405.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2876)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 363, 613)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1479)
[M::mem_pestat] mean and std.dev: (385.96, 233.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1912)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 691872 sequences (100000023 bp) in 1.885 CPU sec, 1.886 real sec...
[M::mem_process_seqs] Processed 692674 reads in 169.633 CPU sec, 5.383 real sec
sorting block 160, #reads = 1071091 mem = 536881119 peak = 1098113024
[M::mem_process_seqs] Processed 692206 reads in 111.124 CPU sec, 3.513 real sec
sorting block 161, #reads = 1069293 mem = 536878705 peak = 1147994112
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 281947, 22, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 275, 665)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1601)
[M::mem_pestat] mean and std.dev: (377.51, 295.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2069)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 280, 409)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 865)
[M::mem_pestat] mean and std.dev: (305.27, 153.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1093)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (73, 875, 987)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2815)
[M::mem_pestat] mean and std.dev: (617.85, 453.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3729)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (242, 397, 853)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2075)
[M::mem_pestat] mean and std.dev: (507.63, 384.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2686)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 691238 sequences (100000107 bp) in 2.178 CPU sec, 2.276 real sec...
[M::process] read 691514 sequences (100000107 bp) in 1.870 CPU sec, 1.874 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 281938, 20, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 316, 1113)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2911)
[M::mem_pestat] mean and std.dev: (479.60, 451.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3810)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 278, 405)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 855)
[M::mem_pestat] mean and std.dev: (303.68, 153.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1080)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (674, 803, 2183)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5201)
[M::mem_pestat] mean and std.dev: (1051.00, 1119.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6710)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 447, 889)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2245)
[M::mem_pestat] mean and std.dev: (536.48, 465.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2923)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 691726 reads in 164.674 CPU sec, 5.222 real sec
[M::mem_process_seqs] Processed 691872 reads in 108.059 CPU sec, 3.513 real sec
sorting block 162, #reads = 1068132 mem = 536879363 peak = 1147994112
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 281516, 20, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 373, 554)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1290)
[M::mem_pestat] mean and std.dev: (386.53, 278.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1658)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 280, 409)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 863)
[M::mem_pestat] mean and std.dev: (306.10, 154.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1090)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (240, 476, 1363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3609)
[M::mem_pestat] mean and std.dev: (641.47, 599.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4732)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 377, 1322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3556)
[M::mem_pestat] mean and std.dev: (568.00, 466.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4673)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 691000 sequences (100000190 bp) in 2.185 CPU sec, 2.272 real sec...
[M::process] read 690532 sequences (100000059 bp) in 1.420 CPU sec, 1.417 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 281777, 21, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 304, 587)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1339)
[M::mem_pestat] mean and std.dev: (365.38, 246.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1715)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 278, 406)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 858)
[M::mem_pestat] mean and std.dev: (304.36, 155.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1084)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (46, 294, 1756)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5176)
[M::mem_pestat] mean and std.dev: (749.00, 1018.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6886)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 250, 710)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1738)
[M::mem_pestat] mean and std.dev: (388.39, 321.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2252)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 691238 reads in 163.879 CPU sec, 5.311 real sec
[M::mem_process_seqs] Processed 691514 reads in 104.380 CPU sec, 3.412 real sec
sorting block 163, #reads = 1069834 mem = 536885342 peak = 1147994112
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 281834, 23, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (248, 336, 703)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1613)
[M::mem_pestat] mean and std.dev: (473.98, 358.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2068)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 282, 412)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 872)
[M::mem_pestat] mean and std.dev: (307.88, 155.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1102)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 982, 2244)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6410)
[M::mem_pestat] mean and std.dev: (1188.48, 1078.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8493)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (266, 450, 844)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2000)
[M::mem_pestat] mean and std.dev: (493.81, 325.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2578)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 690256 sequences (100000019 bp) in 2.193 CPU sec, 2.283 real sec...
[M::process] read 690118 sequences (100000103 bp) in 1.730 CPU sec, 1.734 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 281177, 16, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (228, 369, 1111)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2877)
[M::mem_pestat] mean and std.dev: (519.74, 561.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3760)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 283, 409)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 861)
[M::mem_pestat] mean and std.dev: (306.82, 153.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1087)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (683, 1258, 6956)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 19502)
[M::mem_pestat] mean and std.dev: (2896.31, 3013.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 25775)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 296, 643)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1555)
[M::mem_pestat] mean and std.dev: (401.44, 330.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2011)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 691000 reads in 161.988 CPU sec, 5.232 real sec
sorting block 164, #reads = 1071231 mem = 536877236 peak = 1147994112
[M::mem_process_seqs] Processed 690532 reads in 103.601 CPU sec, 3.279 real sec
sorting block 165, #reads = 1071685 mem = 536880363 peak = 1147994112
[M::process] read 689858 sequences (100000207 bp) in 2.402 CPU sec, 2.513 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 281590, 18, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 278, 671)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1619)
[M::mem_pestat] mean and std.dev: (436.94, 423.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2130)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 284, 411)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 863)
[M::mem_pestat] mean and std.dev: (308.56, 154.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1089)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (455, 1270, 2693)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7169)
[M::mem_pestat] mean and std.dev: (1028.29, 818.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9407)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 406, 718)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1718)
[M::mem_pestat] mean and std.dev: (446.57, 311.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2218)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 689762 sequences (100000148 bp) in 1.770 CPU sec, 1.768 real sec...
[M::mem_process_seqs] Processed 690118 reads in 92.829 CPU sec, 2.938 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 281120, 14, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (233, 315, 710)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1664)
[M::mem_pestat] mean and std.dev: (339.40, 183.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2141)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 283, 410)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 862)
[M::mem_pestat] mean and std.dev: (307.62, 154.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1088)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1258, 1300, 2975)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6409)
[M::mem_pestat] mean and std.dev: (1765.54, 835.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8126)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 291, 422)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 910)
[M::mem_pestat] mean and std.dev: (283.52, 131.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1154)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 280823, 17, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (123, 203, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 747)
[M::mem_pestat] mean and std.dev: (227.86, 147.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 955)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 286, 411)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 863)
[M::mem_pestat] mean and std.dev: (309.65, 154.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1089)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (396, 753, 2248)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5952)
[M::mem_pestat] mean and std.dev: (1090.75, 791.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7804)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 276, 579)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1379)
[M::mem_pestat] mean and std.dev: (365.29, 287.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1779)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 689552 sequences (100000140 bp) in 1.610 CPU sec, 1.620 real sec...
[M::mem_process_seqs] Processed 690256 reads in 248.713 CPU sec, 7.927 real sec
sorting block 166, #reads = 1070628 mem = 536883458 peak = 1147994112
[M::mem_process_seqs] Processed 689858 reads in 122.847 CPU sec, 3.932 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (74, 281044, 18, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 284, 1383)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3797)
[M::mem_pestat] mean and std.dev: (789.29, 917.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5004)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 287, 413)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 869)
[M::mem_pestat] mean and std.dev: (310.42, 155.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1097)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (130, 799, 1125)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3115)
[M::mem_pestat] mean and std.dev: (656.50, 553.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4110)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 366, 488)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1074)
[M::mem_pestat] mean and std.dev: (326.60, 172.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1367)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 167, #reads = 1071650 mem = 536879937 peak = 1147994112
[M::process] read 690284 sequences (100000151 bp) in 2.374 CPU sec, 2.518 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 281323, 9, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 327, 976)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2556)
[M::mem_pestat] mean and std.dev: (482.70, 494.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3346)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 288, 415)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 873)
[M::mem_pestat] mean and std.dev: (312.07, 156.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1102)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 357, 690)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1648)
[M::mem_pestat] mean and std.dev: (357.63, 241.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2127)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 690490 sequences (100000235 bp) in 1.480 CPU sec, 1.485 real sec...
[M::mem_process_seqs] Processed 689762 reads in 149.855 CPU sec, 4.755 real sec
[M::mem_process_seqs] Processed 689552 reads in 99.447 CPU sec, 3.401 real sec
[M::process] read 213016 sequences (30762780 bp) in 0.973 CPU sec, 1.027 real sec...
sorting block 168, #reads = 1071627 mem = 536880903 peak = 1147994112
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 281467, 13, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 259, 556)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1320)
[M::mem_pestat] mean and std.dev: (361.00, 299.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1702)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 287, 416)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 878)
[M::mem_pestat] mean and std.dev: (311.38, 157.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1109)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (51, 777, 1257)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3669)
[M::mem_pestat] mean and std.dev: (699.31, 563.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4875)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 311, 569)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1279)
[M::mem_pestat] mean and std.dev: (390.49, 282.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1634)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (19, 86912, 9, 10)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (293, 629, 1113)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2753)
[M::mem_pestat] mean and std.dev: (712.78, 612.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3573)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 275, 397)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 835)
[M::mem_pestat] mean and std.dev: (298.76, 150.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1054)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 252, 373)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 791)
[M::mem_pestat] mean and std.dev: (247.67, 81.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1000)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 690284 reads in 108.656 CPU sec, 3.752 real sec
sorting block 169, #reads = 1071972 mem = 536881140 peak = 1147994112
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 281341, 12, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 264, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 626)
[M::mem_pestat] mean and std.dev: (248.75, 96.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 773)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 286, 414)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 874)
[M::mem_pestat] mean and std.dev: (310.92, 157.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1104)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (354, 1198, 2050)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5442)
[M::mem_pestat] mean and std.dev: (978.20, 762.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7138)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (284, 354, 1352)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3488)
[M::mem_pestat] mean and std.dev: (656.19, 554.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4556)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 213016 reads in 113.217 CPU sec, 3.659 real sec
[M::mem_process_seqs] Processed 690490 reads in 131.424 CPU sec, 4.244 real sec
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000a06d1
  features: bfebfbff 7ffefbff
  extended: f3bfb7ef fb417ffe
  amd bits: 2c100800 00000121
     brand: Intel(R) Xeon(R) 6975P-C
threads: 31
algo: bwa-mem
license: sentieon:klib=31
reads: 182171248
overall: 70175068160 mem 28956.623 user 606.668 sys 974.038 real
[main] Version: 0.7.17-r1188
[main] CMD: /opt/conda/share/sentieon-202308.03-3/libexec/bwa mem -K 100000000 -Y -R @RG\tID:A23MHWWLT4.1029_FRC-T1-TDNA-1_A23MHWWLT4_1.L002\tPU:L002\tSM:1029_FRC-T1-TDNA-1_A23MHWWLT4_1\tLB:1029_FRC-T1-TDNA-1_A23MHWWLT4_1\tDS:s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta\tPL:ILLUMINA -t 31 ./BWAIndex/Homo_sapiens_assembly38.fasta.64 1029_FRC-T1-TDNA-1_A23MHWWLT4_1_R1.fastq.gz 1029_FRC-T1-TDNA-1_A23MHWWLT4_1_R2.fastq.gz
[main] Real time: 974.077 sec; CPU: 29563.294 sec
sorting block 170, #reads = 940853 mem = 472560317 peak = 1147994112
uniq header count 1
merging 171 blocks
sw version: sentieon-genomics-202308.03
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000a06d1
  features: bfebfbff 7ffefbff
  extended: f3bfb7ef fb417ffe
  amd bits: 2c100800 00000121
     brand: Intel(R) Xeon(R) 6975P-C
threads: 31 max 192
algo: util-sort
license: sentieon:util=1
output file size: 9911649372
output reads: 183453476
bam_mem_sort: 171 calls 101.460 user 2.307 sys 105.919 real
bam_write: 171 calls 80.134 user 5.024 sys 145.449 real
execute: 1 calls 49.332 user 1.200 sys 1031.240 real
merge_files: 1 calls 49.308 user 1.179 sys 55.981 real
parse_chunk: 2735 calls 121.614 user 28.130 sys 174.591 real
read_chunk: 7389 calls 53.199 user 44.467 sys 919.157 real
sort_block: 1 calls 40.092 user 44.106 sys 896.540 real
write_chunk: 4652 calls 48.811 user 0.899 sys 54.914 real
overall: 3624738816 mem 2288.714 user 100.397 sys 1031.260 real
ls: cannot access '*.cram': No such file or directory