This software is licensed to bgold@natera.com by Sentieon Inc.
cmdline: /opt/conda/share/sentieon-202308.03-3/libexec/util sort -r Homo_sapiens_assembly38.fasta -t 31 -o 1136_5TB-T1-TDNA-1_A23MHWWLT4_1.bam --sam2bam -
This software is licensed to bgold@natera.com by Sentieon Inc.
version: sentieon-genomics-202308.03
[M::bwa_idx_load_from_disk] read 3171 ALT contigs
[M::main_mem] bwa index loaded in 1822.260 CPU sec, 63.523 real sec
[M::process] read 694674 sequences (100000179 bp) in 1.105 CPU sec, 1.113 real sec...
[M::process] read 695308 sequences (100000280 bp) in 1.868 CPU sec, 1.873 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 284756, 14, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 411, 1012)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2666)
[M::mem_pestat] mean and std.dev: (643.25, 635.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3493)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 257, 371)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 773)
[M::mem_pestat] mean and std.dev: (281.00, 139.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 974)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 840, 1683)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4689)
[M::mem_pestat] mean and std.dev: (842.07, 672.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6192)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 316, 617)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1399)
[M::mem_pestat] mean and std.dev: (350.86, 193.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1790)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695664 sequences (100000063 bp) in 1.880 CPU sec, 1.947 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 285419, 40, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (240, 351, 613)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1359)
[M::mem_pestat] mean and std.dev: (353.82, 177.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1732)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 256, 371)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 777)
[M::mem_pestat] mean and std.dev: (280.15, 140.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 980)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (102, 673, 1880)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5436)
[M::mem_pestat] mean and std.dev: (1032.85, 1048.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7214)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 349, 587)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1335)
[M::mem_pestat] mean and std.dev: (416.78, 290.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1709)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694000 sequences (100000191 bp) in 1.830 CPU sec, 1.828 real sec...
[M::mem_process_seqs] Processed 694674 reads in 195.049 CPU sec, 6.182 real sec
[M::mem_process_seqs] Processed 695308 reads in 125.511 CPU sec, 3.999 real sec
sorting block 0, #reads = 1082241 mem = 536880026 peak = 596328448
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 284897, 12, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 287, 403)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 883)
[M::mem_pestat] mean and std.dev: (277.41, 136.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1123)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::process] read 694758 sequences (100000045 bp) in 2.557 CPU sec, 2.619 real sec...
[M::mem_pestat] (25, 50, 75) percentile: (171, 260, 376)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 786)
[M::mem_pestat] mean and std.dev: (284.55, 142.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 991)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1041, 1511, 2371)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5031)
[M::mem_pestat] mean and std.dev: (1642.33, 1310.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6885)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 324, 1044)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2810)
[M::mem_pestat] mean and std.dev: (475.32, 420.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3693)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 692916 sequences (100000154 bp) in 2.006 CPU sec, 2.013 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 284861, 19, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 390, 737)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1801)
[M::mem_pestat] mean and std.dev: (458.19, 399.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2333)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 252, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 764)
[M::mem_pestat] mean and std.dev: (277.14, 138.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 963)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (307, 541, 2521)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6949)
[M::mem_pestat] mean and std.dev: (1097.53, 991.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9163)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 255, 485)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1085)
[M::mem_pestat] mean and std.dev: (254.72, 121.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1385)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 694000 reads in 178.175 CPU sec, 5.646 real sec
[M::process] read 693686 sequences (100000220 bp) in 1.978 CPU sec, 1.986 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 285261, 13, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 245, 520)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1238)
[M::mem_pestat] mean and std.dev: (338.58, 265.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1597)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 255, 369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 769)
[M::mem_pestat] mean and std.dev: (279.18, 139.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 969)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (384, 901, 2103)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5541)
[M::mem_pestat] mean and std.dev: (949.82, 735.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7260)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 491, 920)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2330)
[M::mem_pestat] mean and std.dev: (553.43, 461.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3035)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 694758 reads in 100.306 CPU sec, 3.182 real sec
sorting block 1, #reads = 1083343 mem = 536879194 peak = 726876160
[M::mem_process_seqs] Processed 695664 reads in 330.826 CPU sec, 10.540 real sec
sorting block 2, #reads = 1083331 mem = 536879885 peak = 907595776
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 284018, 27, 72)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 211, 660)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1658)
[M::mem_pestat] mean and std.dev: (358.08, 311.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2157)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 259, 372)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 770)
[M::mem_pestat] mean and std.dev: (282.58, 138.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 969)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 408, 1617)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4473)
[M::mem_pestat] mean and std.dev: (816.63, 930.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5901)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 337, 675)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1621)
[M::mem_pestat] mean and std.dev: (398.92, 272.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2094)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 693000 sequences (100000251 bp) in 2.535 CPU sec, 2.611 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 284300, 16, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (223, 358, 526)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1132)
[M::mem_pestat] mean and std.dev: (326.03, 169.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1435)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 258, 370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 768)
[M::mem_pestat] mean and std.dev: (280.99, 138.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 967)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (367, 1132, 3595)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10051)
[M::mem_pestat] mean and std.dev: (2141.56, 2635.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13279)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 329, 642)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1510)
[M::mem_pestat] mean and std.dev: (402.49, 285.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1944)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 691952 sequences (100000088 bp) in 1.892 CPU sec, 1.898 real sec...
[M::mem_process_seqs] Processed 692916 reads in 204.655 CPU sec, 6.513 real sec
[M::process] read 692478 sequences (100000288 bp) in 2.244 CPU sec, 2.248 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 284427, 24, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 248, 497)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1087)
[M::mem_pestat] mean and std.dev: (327.41, 201.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1382)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 257, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 757)
[M::mem_pestat] mean and std.dev: (279.73, 136.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 952)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (253, 1184, 2219)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6151)
[M::mem_pestat] mean and std.dev: (1608.08, 1542.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8117)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 331, 712)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1770)
[M::mem_pestat] mean and std.dev: (413.96, 325.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2299)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 693000 reads in 106.097 CPU sec, 3.507 real sec
sorting block 3, #reads = 1081616 mem = 536879104 peak = 907595776
[M::mem_process_seqs] Processed 693686 reads in 266.353 CPU sec, 8.625 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 284193, 16, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 281, 1743)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4843)
[M::mem_pestat] mean and std.dev: (845.91, 1083.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6393)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 261, 372)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 768)
[M::mem_pestat] mean and std.dev: (283.65, 138.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 966)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (277, 898, 1549)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4093)
[M::mem_pestat] mean and std.dev: (703.93, 556.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5365)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 480, 1274)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3402)
[M::mem_pestat] mean and std.dev: (822.87, 947.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4614)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 4, #reads = 1082445 mem = 536881399 peak = 915206144
[M::process] read 691858 sequences (100000213 bp) in 2.796 CPU sec, 2.907 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 284456, 22, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (248, 322, 835)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2009)
[M::mem_pestat] mean and std.dev: (529.57, 473.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2596)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 258, 369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 761)
[M::mem_pestat] mean and std.dev: (281.02, 136.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 957)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (346, 797, 3021)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8371)
[M::mem_pestat] mean and std.dev: (1981.14, 2070.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11046)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 439, 816)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2002)
[M::mem_pestat] mean and std.dev: (515.72, 423.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2595)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 691952 reads in 202.772 CPU sec, 6.455 real sec
[M::mem_process_seqs] Processed 692478 reads in 126.322 CPU sec, 3.981 real sec
[M::process] read 695754 sequences (100000079 bp) in 2.430 CPU sec, 2.461 real sec...
sorting block 5, #reads = 1080271 mem = 536881603 peak = 915206144
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 283539, 13, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 267, 501)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1161)
[M::mem_pestat] mean and std.dev: (319.77, 243.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1491)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 261, 375)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 777)
[M::mem_pestat] mean and std.dev: (284.82, 140.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 978)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 544, 3395)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9843)
[M::mem_pestat] mean and std.dev: (1374.92, 1474.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13067)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (250, 309, 499)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 997)
[M::mem_pestat] mean and std.dev: (320.78, 175.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1246)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694690 sequences (100000237 bp) in 2.579 CPU sec, 2.648 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 285455, 17, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 278, 396)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 774)
[M::mem_pestat] mean and std.dev: (258.96, 111.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 963)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 254, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 761)
[M::mem_pestat] mean and std.dev: (276.52, 137.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 959)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 457, 1880)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5236)
[M::mem_pestat] mean and std.dev: (602.67, 618.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6914)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 340, 756)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1854)
[M::mem_pestat] mean and std.dev: (386.23, 358.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2403)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694986 sequences (100000060 bp) in 2.120 CPU sec, 2.123 real sec...
[M::mem_process_seqs] Processed 691858 reads in 182.918 CPU sec, 5.808 real sec
[M::mem_process_seqs] Processed 695754 reads in 127.049 CPU sec, 4.014 real sec
sorting block 6, #reads = 1080466 mem = 536880926 peak = 915206144
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 284637, 28, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 313, 534)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1210)
[M::mem_pestat] mean and std.dev: (363.08, 248.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1548)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 258, 371)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 773)
[M::mem_pestat] mean and std.dev: (280.87, 139.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 974)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (353, 498, 1068)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2498)
[M::mem_pestat] mean and std.dev: (626.89, 515.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3213)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (235, 374, 1150)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2980)
[M::mem_pestat] mean and std.dev: (605.08, 524.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3895)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 693998 sequences (100000198 bp) in 2.827 CPU sec, 2.927 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 284975, 28, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 292, 747)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1805)
[M::mem_pestat] mean and std.dev: (457.88, 378.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2334)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 257, 370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 772)
[M::mem_pestat] mean and std.dev: (280.11, 139.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 973)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (535, 625, 2115)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5275)
[M::mem_pestat] mean and std.dev: (985.58, 858.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6855)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 370, 650)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1624)
[M::mem_pestat] mean and std.dev: (399.64, 278.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2111)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694408 sequences (100000278 bp) in 2.190 CPU sec, 2.196 real sec...
[M::mem_process_seqs] Processed 694690 reads in 177.671 CPU sec, 5.619 real sec
sorting block 7, #reads = 1083661 mem = 536878799 peak = 915206144
[M::mem_process_seqs] Processed 694986 reads in 122.098 CPU sec, 3.872 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 285059, 20, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 322, 714)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1748)
[M::mem_pestat] mean and std.dev: (530.98, 525.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2631)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 261, 376)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 784)
[M::mem_pestat] mean and std.dev: (284.07, 141.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 988)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (243, 1087, 1568)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4218)
[M::mem_pestat] mean and std.dev: (1007.16, 1064.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5543)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 374, 733)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1865)
[M::mem_pestat] mean and std.dev: (374.24, 357.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2431)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 8, #reads = 1084346 mem = 536878951 peak = 915206144
[M::process] read 692488 sequences (100000257 bp) in 2.897 CPU sec, 2.971 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 285165, 13, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 265, 885)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2301)
[M::mem_pestat] mean and std.dev: (377.21, 323.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3009)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 258, 372)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 776)
[M::mem_pestat] mean and std.dev: (281.75, 139.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 978)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (6, 116, 2349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7035)
[M::mem_pestat] mean and std.dev: (925.08, 1069.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9378)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 298, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 662)
[M::mem_pestat] mean and std.dev: (249.82, 106.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 813)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 693998 reads in 178.862 CPU sec, 5.664 real sec
[M::process] read 693294 sequences (100000038 bp) in 2.317 CPU sec, 2.320 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 284271, 20, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (140, 305, 957)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2591)
[M::mem_pestat] mean and std.dev: (489.43, 465.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3408)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 263, 377)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 783)
[M::mem_pestat] mean and std.dev: (285.49, 140.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 986)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (277, 698, 1226)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3124)
[M::mem_pestat] mean and std.dev: (789.05, 676.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4073)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 270, 420)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 932)
[M::mem_pestat] mean and std.dev: (278.55, 134.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1188)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 693848 sequences (100000124 bp) in 2.422 CPU sec, 2.436 real sec...
[M::mem_process_seqs] Processed 692488 reads in 102.874 CPU sec, 3.253 real sec
sorting block 9, #reads = 1082864 mem = 536880276 peak = 915206144
[M::mem_process_seqs] Processed 694408 reads in 257.376 CPU sec, 8.157 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 283760, 23, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 258, 795)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2079)
[M::mem_pestat] mean and std.dev: (363.78, 356.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2721)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 258, 368)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 762)
[M::mem_pestat] mean and std.dev: (280.26, 137.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 959)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (450, 1060, 2857)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7671)
[M::mem_pestat] mean and std.dev: (1842.57, 1772.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10078)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 276, 549)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1299)
[M::mem_pestat] mean and std.dev: (286.83, 157.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1674)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 692372 sequences (100000183 bp) in 3.059 CPU sec, 3.150 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 284601, 19, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (127, 280, 394)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 928)
[M::mem_pestat] mean and std.dev: (267.90, 173.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1195)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 255, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 758)
[M::mem_pestat] mean and std.dev: (278.76, 137.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 954)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (607, 928, 1878)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4420)
[M::mem_pestat] mean and std.dev: (1099.94, 840.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5691)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 285, 596)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1424)
[M::mem_pestat] mean and std.dev: (392.18, 307.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1838)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 693294 reads in 202.824 CPU sec, 6.441 real sec
sorting block 10, #reads = 1080973 mem = 536880915 peak = 915206144
[M::mem_process_seqs] Processed 693848 reads in 126.977 CPU sec, 4.002 real sec
[M::process] read 693536 sequences (100000027 bp) in 2.508 CPU sec, 2.555 real sec...
sorting block 11, #reads = 1080841 mem = 536878910 peak = 915206144
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 284223, 22, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 304, 527)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1157)
[M::mem_pestat] mean and std.dev: (330.74, 209.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1472)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 260, 371)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 767)
[M::mem_pestat] mean and std.dev: (282.34, 138.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 965)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (684, 1622, 2053)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4791)
[M::mem_pestat] mean and std.dev: (1214.84, 804.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6160)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 303, 822)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2058)
[M::mem_pestat] mean and std.dev: (512.83, 457.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2676)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 693260 sequences (100000223 bp) in 2.996 CPU sec, 3.118 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 284318, 11, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 295, 544)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1290)
[M::mem_pestat] mean and std.dev: (336.81, 267.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1663)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 256, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 756)
[M::mem_pestat] mean and std.dev: (278.78, 136.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 951)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (480, 1873, 4699)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13137)
[M::mem_pestat] mean and std.dev: (2490.91, 2057.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17356)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (246, 335, 444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 840)
[M::mem_pestat] mean and std.dev: (338.48, 151.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1038)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 692372 reads in 183.055 CPU sec, 5.808 real sec
[M::process] read 695556 sequences (100000091 bp) in 2.197 CPU sec, 2.202 real sec...
[M::mem_process_seqs] Processed 693536 reads in 126.711 CPU sec, 4.005 real sec
sorting block 12, #reads = 1081597 mem = 536879602 peak = 915206144
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 284479, 13, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 303, 710)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1826)
[M::mem_pestat] mean and std.dev: (411.31, 350.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2384)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 257, 368)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 762)
[M::mem_pestat] mean and std.dev: (280.20, 137.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 959)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (249, 317, 2141)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5925)
[M::mem_pestat] mean and std.dev: (860.17, 1194.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7817)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 231, 454)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 998)
[M::mem_pestat] mean and std.dev: (280.91, 170.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1270)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695688 sequences (100000205 bp) in 3.490 CPU sec, 3.725 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 285441, 9, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 246, 597)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1447)
[M::mem_pestat] mean and std.dev: (352.43, 239.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1872)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 253, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 758)
[M::mem_pestat] mean and std.dev: (275.43, 135.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 955)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 287, 857)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2189)
[M::mem_pestat] mean and std.dev: (495.86, 477.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2855)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 693260 reads in 188.447 CPU sec, 5.991 real sec
[M::process] read 693486 sequences (100000164 bp) in 2.196 CPU sec, 2.217 real sec...
[M::mem_process_seqs] Processed 695556 reads in 133.351 CPU sec, 4.220 real sec
sorting block 13, #reads = 1081638 mem = 536878467 peak = 915206144
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 285301, 21, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 290, 391)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 859)
[M::mem_pestat] mean and std.dev: (277.89, 145.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1093)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 253, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 753)
[M::mem_pestat] mean and std.dev: (275.14, 134.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 948)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 427, 2278)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6406)
[M::mem_pestat] mean and std.dev: (1074.05, 1089.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8470)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (231, 347, 1412)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3774)
[M::mem_pestat] mean and std.dev: (608.46, 638.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4955)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695122 sequences (100000005 bp) in 3.001 CPU sec, 3.156 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 285024, 8, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 348, 1734)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4814)
[M::mem_pestat] mean and std.dev: (920.08, 940.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6354)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 264, 378)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 788)
[M::mem_pestat] mean and std.dev: (285.77, 140.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 993)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 258, 772)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1986)
[M::mem_pestat] mean and std.dev: (387.09, 357.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2593)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695688 reads in 182.934 CPU sec, 5.813 real sec
sorting block 14, #reads = 1081674 mem = 536881005 peak = 915206144
[M::process] read 694650 sequences (100000009 bp) in 2.497 CPU sec, 2.514 real sec...
[M::mem_process_seqs] Processed 693486 reads in 127.238 CPU sec, 4.002 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 285571, 12, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 219, 406)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 896)
[M::mem_pestat] mean and std.dev: (281.81, 196.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1141)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 255, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 763)
[M::mem_pestat] mean and std.dev: (278.15, 137.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 961)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (480, 890, 1194)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2622)
[M::mem_pestat] mean and std.dev: (703.00, 289.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3336)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 318, 560)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1240)
[M::mem_pestat] mean and std.dev: (376.30, 268.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1580)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 15, #reads = 1081950 mem = 536877561 peak = 915206144
[M::process] read 693328 sequences (100000269 bp) in 3.067 CPU sec, 3.183 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 284983, 28, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 259, 486)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1106)
[M::mem_pestat] mean and std.dev: (305.13, 217.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1416)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 257, 369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 767)
[M::mem_pestat] mean and std.dev: (279.61, 137.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 966)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (534, 1152, 2673)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6951)
[M::mem_pestat] mean and std.dev: (1507.43, 1498.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9090)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 263, 734)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1852)
[M::mem_pestat] mean and std.dev: (411.69, 399.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2411)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695122 reads in 178.972 CPU sec, 5.671 real sec
[M::process] read 693292 sequences (100000115 bp) in 2.202 CPU sec, 2.211 real sec...
[M::mem_process_seqs] Processed 694650 reads in 125.256 CPU sec, 3.958 real sec
sorting block 16, #reads = 1084189 mem = 536882041 peak = 915206144
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 284624, 34, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 247, 528)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1224)
[M::mem_pestat] mean and std.dev: (336.26, 240.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1572)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 261, 375)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 781)
[M::mem_pestat] mean and std.dev: (284.09, 140.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 984)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (371, 799, 1149)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2705)
[M::mem_pestat] mean and std.dev: (912.28, 670.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3596)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 231, 610)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1482)
[M::mem_pestat] mean and std.dev: (284.58, 217.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1918)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 693484 sequences (100000107 bp) in 2.945 CPU sec, 3.062 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 284389, 8, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 325, 921)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2445)
[M::mem_pestat] mean and std.dev: (387.53, 412.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3207)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 260, 372)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 772)
[M::mem_pestat] mean and std.dev: (282.44, 138.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 972)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 348, 534)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1200)
[M::mem_pestat] mean and std.dev: (335.02, 164.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1533)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 693744 sequences (100000023 bp) in 2.048 CPU sec, 2.054 real sec...
[M::mem_process_seqs] Processed 693328 reads in 180.830 CPU sec, 5.725 real sec
sorting block 17, #reads = 1082401 mem = 536880747 peak = 915206144
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 284603, 23, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 262, 584)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1418)
[M::mem_pestat] mean and std.dev: (330.61, 275.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1835)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 257, 368)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 762)
[M::mem_pestat] mean and std.dev: (280.38, 137.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 959)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (659, 1748, 2628)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6566)
[M::mem_pestat] mean and std.dev: (1920.91, 1776.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9028)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (248, 365, 707)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1625)
[M::mem_pestat] mean and std.dev: (436.59, 368.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2084)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 693244 sequences (100000281 bp) in 2.687 CPU sec, 2.691 real sec...
[M::mem_process_seqs] Processed 693484 reads in 102.350 CPU sec, 3.224 real sec
[M::mem_process_seqs] Processed 693292 reads in 264.451 CPU sec, 8.386 real sec
sorting block 18, #reads = 1081329 mem = 536880937 peak = 915206144
[M::process] read 693576 sequences (100000064 bp) in 3.058 CPU sec, 3.180 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 283987, 28, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 254, 556)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1356)
[M::mem_pestat] mean and std.dev: (311.48, 203.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1756)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 256, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 753)
[M::mem_pestat] mean and std.dev: (278.52, 136.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 947)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (59, 355, 1994)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5864)
[M::mem_pestat] mean and std.dev: (944.92, 1378.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7799)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 296, 637)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1455)
[M::mem_pestat] mean and std.dev: (389.22, 270.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1864)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 693244 reads in 103.199 CPU sec, 3.246 real sec
[M::process] read 694156 sequences (100000009 bp) in 2.649 CPU sec, 2.724 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 284318, 25, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 297, 463)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1047)
[M::mem_pestat] mean and std.dev: (278.79, 157.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1339)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 256, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 755)
[M::mem_pestat] mean and std.dev: (278.19, 136.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 950)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (322, 580, 1224)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3028)
[M::mem_pestat] mean and std.dev: (608.17, 434.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3930)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 427, 1149)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3043)
[M::mem_pestat] mean and std.dev: (781.08, 882.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4313)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 19, #reads = 1080977 mem = 536879206 peak = 915206144
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 284568, 8, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 260, 708)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1740)
[M::mem_pestat] mean and std.dev: (404.25, 368.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2256)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 256, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 756)
[M::mem_pestat] mean and std.dev: (278.70, 136.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 951)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 276, 509)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1109)
[M::mem_pestat] mean and std.dev: (338.79, 208.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1409)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 693744 reads in 306.484 CPU sec, 9.735 real sec
[M::mem_process_seqs] Processed 693576 reads in 152.142 CPU sec, 4.805 real sec
[M::process] read 692808 sequences (100000090 bp) in 2.746 CPU sec, 2.801 real sec...
sorting block 20, #reads = 1081667 mem = 536882377 peak = 915206144
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 284576, 23, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 258, 727)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1857)
[M::mem_pestat] mean and std.dev: (375.39, 375.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2422)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 257, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 758)
[M::mem_pestat] mean and std.dev: (278.19, 135.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 954)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 550, 832)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2096)
[M::mem_pestat] mean and std.dev: (488.76, 373.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2728)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 301, 770)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1940)
[M::mem_pestat] mean and std.dev: (478.31, 434.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2525)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 693592 sequences (100000207 bp) in 2.567 CPU sec, 2.679 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 284472, 16, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 218, 586)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1446)
[M::mem_pestat] mean and std.dev: (373.24, 316.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1876)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 262, 372)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 770)
[M::mem_pestat] mean and std.dev: (282.72, 137.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 969)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (893, 893, 7654)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 21176)
[M::mem_pestat] mean and std.dev: (2792.62, 3104.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 27937)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 286, 418)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 844)
[M::mem_pestat] mean and std.dev: (283.88, 132.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1057)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 693884 sequences (100000196 bp) in 1.930 CPU sec, 1.933 real sec...
[M::mem_process_seqs] Processed 694156 reads in 179.361 CPU sec, 5.702 real sec
[M::mem_process_seqs] Processed 692808 reads in 123.457 CPU sec, 3.909 real sec
sorting block 21, #reads = 1081509 mem = 536880454 peak = 915206144
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 284802, 20, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (235, 366, 576)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1258)
[M::mem_pestat] mean and std.dev: (404.48, 246.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1599)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 261, 371)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 769)
[M::mem_pestat] mean and std.dev: (281.63, 137.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 968)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (457, 1267, 2020)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5146)
[M::mem_pestat] mean and std.dev: (1408.30, 1167.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6709)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 237, 415)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 883)
[M::mem_pestat] mean and std.dev: (282.92, 159.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1117)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695582 sequences (100000291 bp) in 3.236 CPU sec, 3.355 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 284927, 12, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (137, 358, 1646)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4664)
[M::mem_pestat] mean and std.dev: (842.74, 886.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6173)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 261, 374)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 778)
[M::mem_pestat] mean and std.dev: (283.15, 139.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 980)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (346, 577, 4569)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13015)
[M::mem_pestat] mean and std.dev: (2420.92, 2672.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17238)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 358, 560)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1294)
[M::mem_pestat] mean and std.dev: (368.78, 219.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1661)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 693592 reads in 174.910 CPU sec, 5.545 real sec
[M::process] read 694830 sequences (100000242 bp) in 2.352 CPU sec, 2.369 real sec...
[M::mem_process_seqs] Processed 693884 reads in 123.080 CPU sec, 3.879 real sec
sorting block 22, #reads = 1083016 mem = 536876957 peak = 915206144
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 284996, 13, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 390, 946)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2408)
[M::mem_pestat] mean and std.dev: (490.65, 366.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3139)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 253, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 758)
[M::mem_pestat] mean and std.dev: (275.88, 136.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 955)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (579, 976, 1492)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3318)
[M::mem_pestat] mean and std.dev: (1083.62, 541.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4231)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 296, 771)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1951)
[M::mem_pestat] mean and std.dev: (411.44, 362.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2541)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 693114 sequences (100000159 bp) in 2.904 CPU sec, 3.028 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 284763, 30, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (134, 252, 610)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1562)
[M::mem_pestat] mean and std.dev: (390.15, 316.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2038)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 254, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 760)
[M::mem_pestat] mean and std.dev: (277.93, 137.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 957)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (440, 1033, 4074)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 11342)
[M::mem_pestat] mean and std.dev: (1979.83, 1907.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14976)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 299, 398)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 766)
[M::mem_pestat] mean and std.dev: (312.65, 156.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 950)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 693440 sequences (100000292 bp) in 2.193 CPU sec, 2.202 real sec...
[M::mem_process_seqs] Processed 695582 reads in 182.332 CPU sec, 5.788 real sec
sorting block 23, #reads = 1083491 mem = 536882440 peak = 915206144
[M::mem_process_seqs] Processed 694830 reads in 127.239 CPU sec, 4.036 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 284616, 23, 75)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 333, 1090)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2936)
[M::mem_pestat] mean and std.dev: (583.76, 579.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3859)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 263, 376)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 782)
[M::mem_pestat] mean and std.dev: (284.88, 140.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 985)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (533, 798, 1804)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4346)
[M::mem_pestat] mean and std.dev: (1158.13, 938.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5617)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (246, 422, 1044)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2640)
[M::mem_pestat] mean and std.dev: (688.88, 620.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3438)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 24, #reads = 1082573 mem = 536880096 peak = 955744256
[M::process] read 693670 sequences (100000199 bp) in 3.210 CPU sec, 3.323 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 284179, 20, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 299, 640)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1584)
[M::mem_pestat] mean and std.dev: (325.16, 276.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2056)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 260, 373)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 775)
[M::mem_pestat] mean and std.dev: (283.14, 139.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 976)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (523, 716, 1251)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2707)
[M::mem_pestat] mean and std.dev: (603.62, 278.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3435)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 339, 744)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1846)
[M::mem_pestat] mean and std.dev: (360.05, 298.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2397)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 693114 reads in 181.110 CPU sec, 5.733 real sec
[M::process] read 693830 sequences (100000202 bp) in 2.465 CPU sec, 2.486 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 284364, 23, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 363, 578)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1348)
[M::mem_pestat] mean and std.dev: (360.00, 194.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1733)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 256, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 756)
[M::mem_pestat] mean and std.dev: (278.86, 136.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 951)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 349, 1441)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3997)
[M::mem_pestat] mean and std.dev: (686.45, 790.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5275)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 212, 422)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 924)
[M::mem_pestat] mean and std.dev: (264.41, 152.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1175)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 693590 sequences (100000063 bp) in 2.625 CPU sec, 2.632 real sec...
[M::mem_process_seqs] Processed 693670 reads in 105.565 CPU sec, 3.335 real sec
sorting block 25, #reads = 1082150 mem = 536877951 peak = 955744256
[M::mem_process_seqs] Processed 693440 reads in 262.071 CPU sec, 8.302 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 284453, 21, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 460, 967)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2461)
[M::mem_pestat] mean and std.dev: (469.62, 400.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3208)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 254, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 752)
[M::mem_pestat] mean and std.dev: (277.55, 136.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 946)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (940, 1205, 2478)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5554)
[M::mem_pestat] mean and std.dev: (1616.76, 1060.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7092)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 274, 540)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1180)
[M::mem_pestat] mean and std.dev: (317.57, 206.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1500)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 26, #reads = 1081357 mem = 536879368 peak = 955744256
[M::process] read 697432 sequences (100000110 bp) in 3.118 CPU sec, 3.234 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (74, 284241, 21, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 287, 1185)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3161)
[M::mem_pestat] mean and std.dev: (519.48, 529.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4149)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 256, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 756)
[M::mem_pestat] mean and std.dev: (279.15, 137.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 951)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (253, 502, 2228)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6178)
[M::mem_pestat] mean and std.dev: (1124.71, 1141.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8153)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 351, 846)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2206)
[M::mem_pestat] mean and std.dev: (549.66, 547.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2886)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 693830 reads in 209.817 CPU sec, 6.652 real sec
[M::mem_process_seqs] Processed 693590 reads in 129.581 CPU sec, 4.081 real sec
[M::process] read 697918 sequences (100000003 bp) in 2.604 CPU sec, 2.639 real sec...
sorting block 27, #reads = 1080684 mem = 536878986 peak = 955744256
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 286083, 24, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 225, 637)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1593)
[M::mem_pestat] mean and std.dev: (327.69, 269.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2071)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 244, 356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 742)
[M::mem_pestat] mean and std.dev: (270.62, 136.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 935)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (257, 574, 2180)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6026)
[M::mem_pestat] mean and std.dev: (1213.08, 1242.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7949)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (230, 393, 848)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2084)
[M::mem_pestat] mean and std.dev: (450.26, 325.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2702)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699050 sequences (100000145 bp) in 3.094 CPU sec, 3.208 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 286496, 17, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 195, 936)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2510)
[M::mem_pestat] mean and std.dev: (391.78, 450.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3297)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 245, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 762)
[M::mem_pestat] mean and std.dev: (273.18, 139.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 962)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 477, 1703)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4701)
[M::mem_pestat] mean and std.dev: (598.67, 575.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6200)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 279, 373)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 675)
[M::mem_pestat] mean and std.dev: (283.54, 105.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 826)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696294 sequences (100000190 bp) in 2.269 CPU sec, 2.265 real sec...
[M::mem_process_seqs] Processed 697432 reads in 194.238 CPU sec, 6.154 real sec
[M::mem_process_seqs] Processed 697918 reads in 132.764 CPU sec, 4.202 real sec
sorting block 28, #reads = 1081054 mem = 536881456 peak = 955744256
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (73, 286749, 19, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 211, 507)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1217)
[M::mem_pestat] mean and std.dev: (298.71, 259.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1572)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 240, 353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 739)
[M::mem_pestat] mean and std.dev: (267.53, 135.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 932)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (544, 898, 1792)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4288)
[M::mem_pestat] mean and std.dev: (1140.83, 1091.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5536)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 356, 680)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1668)
[M::mem_pestat] mean and std.dev: (448.00, 338.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2162)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697940 sequences (100000257 bp) in 3.306 CPU sec, 3.413 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 286433, 12, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 528, 1051)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2717)
[M::mem_pestat] mean and std.dev: (586.42, 454.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3550)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 249, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 765)
[M::mem_pestat] mean and std.dev: (276.03, 139.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 965)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 972, 3454)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9940)
[M::mem_pestat] mean and std.dev: (1955.58, 2303.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13183)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 329, 525)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1135)
[M::mem_pestat] mean and std.dev: (412.62, 284.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1552)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699050 reads in 192.138 CPU sec, 6.080 real sec
[M::process] read 694914 sequences (100000060 bp) in 2.509 CPU sec, 2.503 real sec...
sorting block 29, #reads = 1082438 mem = 536878628 peak = 955744256
[M::mem_process_seqs] Processed 696294 reads in 133.354 CPU sec, 4.208 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 286245, 22, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 355, 963)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2505)
[M::mem_pestat] mean and std.dev: (558.43, 556.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3276)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 243, 356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 744)
[M::mem_pestat] mean and std.dev: (270.12, 136.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 938)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 1022, 2142)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6076)
[M::mem_pestat] mean and std.dev: (1257.91, 1208.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8043)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 312, 586)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1386)
[M::mem_pestat] mean and std.dev: (328.21, 226.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1786)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694506 sequences (100000175 bp) in 2.781 CPU sec, 2.860 real sec...
[M::process] read 693444 sequences (100000259 bp) in 2.053 CPU sec, 2.060 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 285263, 19, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 351, 799)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2023)
[M::mem_pestat] mean and std.dev: (390.34, 281.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2635)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 254, 371)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 775)
[M::mem_pestat] mean and std.dev: (280.45, 140.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 977)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (261, 426, 702)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1584)
[M::mem_pestat] mean and std.dev: (457.39, 349.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2025)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 371, 532)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1108)
[M::mem_pestat] mean and std.dev: (358.87, 162.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1396)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697940 reads in 191.934 CPU sec, 6.082 real sec
sorting block 30, #reads = 1082911 mem = 536878948 peak = 955744256
[M::mem_process_seqs] Processed 694914 reads in 132.528 CPU sec, 4.208 real sec
sorting block 31, #reads = 1080151 mem = 536880433 peak = 998481920
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 284838, 11, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 298, 511)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1181)
[M::mem_pestat] mean and std.dev: (340.03, 239.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1516)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 254, 368)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 766)
[M::mem_pestat] mean and std.dev: (278.88, 138.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 965)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (580, 646, 1229)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2527)
[M::mem_pestat] mean and std.dev: (714.89, 360.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3176)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 304, 482)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1056)
[M::mem_pestat] mean and std.dev: (325.19, 175.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1343)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 693990 sequences (100000179 bp) in 2.861 CPU sec, 2.934 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 284745, 28, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 317, 684)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1728)
[M::mem_pestat] mean and std.dev: (383.08, 297.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2250)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 258, 373)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 777)
[M::mem_pestat] mean and std.dev: (282.79, 140.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 979)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (142, 450, 647)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1657)
[M::mem_pestat] mean and std.dev: (367.04, 345.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2162)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 279, 545)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1279)
[M::mem_pestat] mean and std.dev: (350.18, 241.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1646)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 693534 sequences (100000049 bp) in 2.335 CPU sec, 2.338 real sec...
[M::mem_process_seqs] Processed 694506 reads in 192.131 CPU sec, 6.088 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 284614, 20, 72)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 266, 533)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1303)
[M::mem_pestat] mean and std.dev: (277.49, 226.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1688)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 254, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 760)
[M::mem_pestat] mean and std.dev: (278.42, 137.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 957)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (277, 916, 2607)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7267)
[M::mem_pestat] mean and std.dev: (1292.15, 1123.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9597)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (280, 371, 616)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1288)
[M::mem_pestat] mean and std.dev: (395.79, 210.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1624)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698992 sequences (100000259 bp) in 2.529 CPU sec, 2.539 real sec...
[M::mem_process_seqs] Processed 693990 reads in 111.476 CPU sec, 3.764 real sec
sorting block 32, #reads = 1080366 mem = 536876771 peak = 998481920
[M::mem_process_seqs] Processed 693444 reads in 280.674 CPU sec, 9.150 real sec
sorting block 33, #reads = 1078334 mem = 536880903 peak = 1003958272
[M::process] read 700864 sequences (100000232 bp) in 3.111 CPU sec, 3.231 real sec...
[M::process] read 698882 sequences (100000268 bp) in 2.336 CPU sec, 2.338 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 287078, 20, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 274, 401)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 875)
[M::mem_pestat] mean and std.dev: (269.98, 127.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1112)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 237, 348)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 728)
[M::mem_pestat] mean and std.dev: (263.14, 132.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 918)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (138, 579, 1558)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4398)
[M::mem_pestat] mean and std.dev: (825.00, 939.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5818)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 270, 435)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 887)
[M::mem_pestat] mean and std.dev: (297.72, 122.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1113)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700864 reads in 119.083 CPU sec, 3.859 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 286809, 24, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 259, 646)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1626)
[M::mem_pestat] mean and std.dev: (289.61, 191.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2116)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 241, 352)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 734)
[M::mem_pestat] mean and std.dev: (267.16, 134.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 925)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (366, 673, 918)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2022)
[M::mem_pestat] mean and std.dev: (591.78, 306.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2574)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 293, 435)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 851)
[M::mem_pestat] mean and std.dev: (279.84, 123.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1059)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698992 reads in 236.712 CPU sec, 8.286 real sec
sorting block 34, #reads = 1076892 mem = 536888649 peak = 1003958272
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 284848, 29, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 328, 456)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 964)
[M::mem_pestat] mean and std.dev: (314.51, 161.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1218)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 256, 369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 767)
[M::mem_pestat] mean and std.dev: (280.34, 138.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 966)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (353, 985, 2041)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5417)
[M::mem_pestat] mean and std.dev: (1248.14, 1027.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7105)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 256, 396)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 858)
[M::mem_pestat] mean and std.dev: (276.00, 159.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1089)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698028 sequences (100000198 bp) in 3.355 CPU sec, 3.461 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 287060, 18, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 302, 1085)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2875)
[M::mem_pestat] mean and std.dev: (699.73, 761.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3770)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 241, 350)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 728)
[M::mem_pestat] mean and std.dev: (265.78, 132.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 917)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (123, 988, 1144)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3186)
[M::mem_pestat] mean and std.dev: (652.69, 466.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4207)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 208, 383)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 853)
[M::mem_pestat] mean and std.dev: (245.55, 144.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1088)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 693534 reads in 460.784 CPU sec, 15.425 real sec
[M::mem_process_seqs] Processed 698882 reads in 174.799 CPU sec, 5.580 real sec
sorting block 35, #reads = 1077930 mem = 536878808 peak = 1003958272
[M::process] read 697538 sequences (100000187 bp) in 2.901 CPU sec, 2.987 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 287129, 18, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 262, 609)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1481)
[M::mem_pestat] mean and std.dev: (342.45, 241.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1917)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 244, 354)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 736)
[M::mem_pestat] mean and std.dev: (268.46, 133.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 927)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (509, 1053, 2107)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5303)
[M::mem_pestat] mean and std.dev: (971.93, 957.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6901)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 205, 276)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 518)
[M::mem_pestat] mean and std.dev: (218.32, 83.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 639)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695432 sequences (100000022 bp) in 2.576 CPU sec, 2.680 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 286213, 22, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 347, 742)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1910)
[M::mem_pestat] mean and std.dev: (473.06, 433.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2494)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 244, 355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 739)
[M::mem_pestat] mean and std.dev: (269.54, 134.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 931)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (262, 1205, 1924)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5248)
[M::mem_pestat] mean and std.dev: (1298.81, 1481.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7226)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 347, 626)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1516)
[M::mem_pestat] mean and std.dev: (375.77, 225.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1961)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695094 sequences (100000213 bp) in 2.170 CPU sec, 2.168 real sec...
[M::mem_process_seqs] Processed 698028 reads in 206.116 CPU sec, 6.550 real sec
sorting block 36, #reads = 1078629 mem = 536883183 peak = 1003958272
[M::mem_process_seqs] Processed 697538 reads in 140.565 CPU sec, 4.457 real sec
sorting block 37, #reads = 1079919 mem = 536882145 peak = 1004269568
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 285774, 18, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 294, 653)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1571)
[M::mem_pestat] mean and std.dev: (375.48, 302.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2030)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 254, 369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 771)
[M::mem_pestat] mean and std.dev: (278.92, 139.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 972)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (537, 995, 1332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2922)
[M::mem_pestat] mean and std.dev: (773.13, 444.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3717)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (236, 383, 573)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1247)
[M::mem_pestat] mean and std.dev: (345.05, 192.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1584)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 693628 sequences (100000179 bp) in 3.084 CPU sec, 3.183 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 285203, 22, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 305, 491)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1087)
[M::mem_pestat] mean and std.dev: (302.70, 183.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1385)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::process] read 694402 sequences (100000072 bp) in 2.106 CPU sec, 2.109 real sec...
[M::mem_pestat] (25, 50, 75) percentile: (168, 252, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 765)
[M::mem_pestat] mean and std.dev: (278.10, 139.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 964)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (407, 633, 1516)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3734)
[M::mem_pestat] mean and std.dev: (783.14, 548.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4843)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 243, 401)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 877)
[M::mem_pestat] mean and std.dev: (259.49, 127.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1115)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695432 reads in 198.392 CPU sec, 6.298 real sec
[M::mem_process_seqs] Processed 695094 reads in 138.714 CPU sec, 4.410 real sec
sorting block 38, #reads = 1079397 mem = 536878245 peak = 1004269568
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 284643, 17, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 337, 741)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1853)
[M::mem_pestat] mean and std.dev: (458.76, 386.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2409)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 258, 374)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 780)
[M::mem_pestat] mean and std.dev: (282.91, 141.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 983)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 1148, 2577)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7307)
[M::mem_pestat] mean and std.dev: (1106.69, 1066.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9672)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 313, 533)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1203)
[M::mem_pestat] mean and std.dev: (322.03, 201.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1538)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694972 sequences (100000097 bp) in 2.980 CPU sec, 3.099 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 284674, 16, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 390, 728)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1814)
[M::mem_pestat] mean and std.dev: (456.42, 385.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2357)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 254, 368)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 766)
[M::mem_pestat] mean and std.dev: (279.40, 139.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 965)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (466, 779, 1453)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3427)
[M::mem_pestat] mean and std.dev: (1045.19, 839.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4414)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 297, 582)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1330)
[M::mem_pestat] mean and std.dev: (337.45, 188.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1704)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699784 sequences (100000103 bp) in 2.386 CPU sec, 2.394 real sec...
[M::mem_process_seqs] Processed 693628 reads in 193.904 CPU sec, 6.131 real sec
[M::mem_process_seqs] Processed 694402 reads in 135.693 CPU sec, 4.292 real sec
sorting block 39, #reads = 1078665 mem = 536879198 peak = 1004269568
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 284467, 8, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 302, 556)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1254)
[M::mem_pestat] mean and std.dev: (346.46, 212.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1603)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 251, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 764)
[M::mem_pestat] mean and std.dev: (277.51, 139.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 963)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 294, 581)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1297)
[M::mem_pestat] mean and std.dev: (383.55, 242.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1655)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 697408 sequences (100000169 bp) in 3.183 CPU sec, 3.301 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 287205, 17, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 273, 977)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2609)
[M::mem_pestat] mean and std.dev: (448.52, 490.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3425)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 239, 351)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 733)
[M::mem_pestat] mean and std.dev: (265.59, 133.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 924)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (435, 777, 1482)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3576)
[M::mem_pestat] mean and std.dev: (779.25, 552.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4623)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 309, 622)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1490)
[M::mem_pestat] mean and std.dev: (408.84, 335.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1924)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695860 sequences (100000021 bp) in 2.339 CPU sec, 2.349 real sec...
[M::mem_process_seqs] Processed 694972 reads in 206.506 CPU sec, 6.539 real sec
sorting block 40, #reads = 1078840 mem = 536879677 peak = 1004269568
[M::mem_process_seqs] Processed 699784 reads in 138.236 CPU sec, 4.382 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 285779, 16, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (263, 330, 1365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3569)
[M::mem_pestat] mean and std.dev: (678.87, 658.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4671)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 246, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 754)
[M::mem_pestat] mean and std.dev: (271.98, 136.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 951)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (126, 421, 2115)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6093)
[M::mem_pestat] mean and std.dev: (1191.94, 1530.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8082)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 281, 400)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 748)
[M::mem_pestat] mean and std.dev: (285.49, 137.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 922)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 41, #reads = 1076851 mem = 536878599 peak = 1004269568
[M::process] read 698022 sequences (100000176 bp) in 2.731 CPU sec, 2.848 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 286258, 34, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 359, 1796)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4974)
[M::mem_pestat] mean and std.dev: (803.66, 1053.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6563)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 254, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 767)
[M::mem_pestat] mean and std.dev: (277.65, 138.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 967)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (245, 861, 1124)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2882)
[M::mem_pestat] mean and std.dev: (788.39, 684.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3761)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 256, 407)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 903)
[M::mem_pestat] mean and std.dev: (285.74, 192.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1151)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697184 sequences (100000059 bp) in 2.038 CPU sec, 2.043 real sec...
[M::mem_process_seqs] Processed 697408 reads in 187.523 CPU sec, 6.158 real sec
[M::mem_process_seqs] Processed 695860 reads in 124.398 CPU sec, 3.946 real sec
sorting block 42, #reads = 1082453 mem = 536878041 peak = 1004269568
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 286515, 14, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 366, 873)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2261)
[M::mem_pestat] mean and std.dev: (414.94, 388.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2955)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 243, 351)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 729)
[M::mem_pestat] mean and std.dev: (267.08, 131.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 918)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (64, 521, 2548)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7516)
[M::mem_pestat] mean and std.dev: (1105.86, 1347.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10000)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (321, 543, 759)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1635)
[M::mem_pestat] mean and std.dev: (525.14, 305.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2073)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695566 sequences (100000248 bp) in 2.844 CPU sec, 2.969 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 286133, 12, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 307, 632)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1544)
[M::mem_pestat] mean and std.dev: (429.65, 375.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2000)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 247, 357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 743)
[M::mem_pestat] mean and std.dev: (271.00, 134.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 936)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (621, 1365, 2582)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6504)
[M::mem_pestat] mean and std.dev: (1485.00, 1070.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8465)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 359, 1049)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2745)
[M::mem_pestat] mean and std.dev: (683.71, 670.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3593)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696224 sequences (100000031 bp) in 2.147 CPU sec, 2.161 real sec...
[M::mem_process_seqs] Processed 698022 reads in 188.161 CPU sec, 5.979 real sec
[M::mem_process_seqs] Processed 697184 reads in 128.103 CPU sec, 4.051 real sec
sorting block 43, #reads = 1081423 mem = 536878831 peak = 1004269568
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 285432, 18, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 258, 369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 767)
[M::mem_pestat] mean and std.dev: (279.35, 153.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 966)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 253, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 767)
[M::mem_pestat] mean and std.dev: (277.46, 138.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 967)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (448, 1040, 2685)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7159)
[M::mem_pestat] mean and std.dev: (1625.94, 1990.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9589)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 347, 530)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1228)
[M::mem_pestat] mean and std.dev: (350.14, 225.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1577)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695450 sequences (100000033 bp) in 2.739 CPU sec, 2.828 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 285579, 14, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 363, 756)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1854)
[M::mem_pestat] mean and std.dev: (464.37, 373.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2403)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 249, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 750)
[M::mem_pestat] mean and std.dev: (273.35, 135.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 945)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 1152, 2474)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7026)
[M::mem_pestat] mean and std.dev: (1215.07, 1089.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9302)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 252, 485)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1139)
[M::mem_pestat] mean and std.dev: (316.83, 197.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1466)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695566 reads in 185.677 CPU sec, 5.890 real sec
[M::process] read 695240 sequences (100000072 bp) in 2.319 CPU sec, 2.325 real sec...
sorting block 44, #reads = 1081662 mem = 536881623 peak = 1004269568
[M::mem_process_seqs] Processed 696224 reads in 128.165 CPU sec, 4.048 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 285507, 31, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 255, 483)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1105)
[M::mem_pestat] mean and std.dev: (283.93, 184.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1416)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 251, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 761)
[M::mem_pestat] mean and std.dev: (276.64, 138.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 959)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (385, 641, 1136)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2638)
[M::mem_pestat] mean and std.dev: (670.29, 378.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3389)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 271, 389)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 789)
[M::mem_pestat] mean and std.dev: (254.05, 108.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 989)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695992 sequences (100000076 bp) in 2.838 CPU sec, 2.906 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 284717, 17, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 381, 896)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2288)
[M::mem_pestat] mean and std.dev: (517.07, 414.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2984)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 251, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 761)
[M::mem_pestat] mean and std.dev: (276.57, 138.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 959)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 475, 1640)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4516)
[M::mem_pestat] mean and std.dev: (937.35, 1166.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5954)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 297, 611)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1405)
[M::mem_pestat] mean and std.dev: (355.94, 249.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1802)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701602 sequences (100000054 bp) in 2.420 CPU sec, 2.423 real sec...
[M::mem_process_seqs] Processed 695450 reads in 192.427 CPU sec, 6.088 real sec
sorting block 45, #reads = 1081150 mem = 536879679 peak = 1004269568
[M::mem_process_seqs] Processed 695240 reads in 133.446 CPU sec, 4.211 real sec
sorting block 46, #reads = 1078337 mem = 536878134 peak = 1004269568
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (76, 285191, 27, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 298, 626)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1484)
[M::mem_pestat] mean and std.dev: (403.54, 269.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1913)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 246, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 744)
[M::mem_pestat] mean and std.dev: (272.50, 136.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 937)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (423, 785, 1068)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2358)
[M::mem_pestat] mean and std.dev: (707.52, 410.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3003)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 352, 1297)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3513)
[M::mem_pestat] mean and std.dev: (590.93, 662.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4621)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700572 sequences (100000055 bp) in 2.914 CPU sec, 2.996 real sec...
[M::process] read 699318 sequences (100000237 bp) in 2.364 CPU sec, 2.367 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 286871, 23, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 298, 547)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1301)
[M::mem_pestat] mean and std.dev: (311.87, 254.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1678)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 235, 346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 724)
[M::mem_pestat] mean and std.dev: (261.45, 131.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 913)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (393, 655, 1105)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2529)
[M::mem_pestat] mean and std.dev: (791.27, 454.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3241)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 311, 1729)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4797)
[M::mem_pestat] mean and std.dev: (827.73, 982.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6331)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695992 reads in 212.475 CPU sec, 6.732 real sec
[M::mem_process_seqs] Processed 701602 reads in 153.785 CPU sec, 4.883 real sec
sorting block 47, #reads = 1074172 mem = 536881914 peak = 1004269568
[M::process] read 700466 sequences (100000096 bp) in 2.625 CPU sec, 2.699 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 287275, 21, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 256, 396)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 840)
[M::mem_pestat] mean and std.dev: (270.51, 153.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1062)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 237, 347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 723)
[M::mem_pestat] mean and std.dev: (262.29, 130.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 911)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (463, 685, 2107)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5395)
[M::mem_pestat] mean and std.dev: (852.37, 704.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7039)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 219, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 782)
[M::mem_pestat] mean and std.dev: (225.88, 129.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 990)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697692 sequences (100000289 bp) in 2.360 CPU sec, 2.357 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 287161, 8, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 281, 518)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1214)
[M::mem_pestat] mean and std.dev: (338.27, 219.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1562)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 241, 354)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 742)
[M::mem_pestat] mean and std.dev: (267.37, 134.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 936)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (232, 329, 688)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1600)
[M::mem_pestat] mean and std.dev: (410.43, 317.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2056)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 287299, 17, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 254, 835)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2179)
[M::mem_pestat] mean and std.dev: (436.45, 427.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2851)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 234, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 704)
[M::mem_pestat] mean and std.dev: (258.89, 127.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 886)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 730, 1762)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4974)
[M::mem_pestat] mean and std.dev: (915.19, 962.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6580)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 433, 1212)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3232)
[M::mem_pestat] mean and std.dev: (695.92, 668.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4242)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700572 reads in 289.383 CPU sec, 9.215 real sec
[M::mem_process_seqs] Processed 699318 reads in 224.726 CPU sec, 7.187 real sec
sorting block 48, #reads = 1075736 mem = 536876376 peak = 1004269568
[M::mem_process_seqs] Processed 700466 reads in 251.223 CPU sec, 8.051 real sec
sorting block 49, #reads = 1078681 mem = 536882775 peak = 1004269568
[M::process] read 697592 sequences (100000093 bp) in 2.795 CPU sec, 2.924 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 286118, 19, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 283, 699)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1777)
[M::mem_pestat] mean and std.dev: (366.47, 324.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2316)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 245, 354)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 736)
[M::mem_pestat] mean and std.dev: (268.69, 132.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 927)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (520, 781, 1450)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3310)
[M::mem_pestat] mean and std.dev: (919.32, 683.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4240)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 241, 484)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1030)
[M::mem_pestat] mean and std.dev: (277.80, 154.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1303)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696478 sequences (100000072 bp) in 2.663 CPU sec, 2.740 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 286309, 30, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (255, 521, 1485)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3945)
[M::mem_pestat] mean and std.dev: (785.74, 736.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5175)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 245, 354)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 736)
[M::mem_pestat] mean and std.dev: (268.98, 132.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 927)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 361, 2661)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7567)
[M::mem_pestat] mean and std.dev: (1547.53, 1772.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10020)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 298, 458)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 986)
[M::mem_pestat] mean and std.dev: (289.44, 144.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1250)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697692 reads in 199.020 CPU sec, 6.325 real sec
[M::mem_process_seqs] Processed 697592 reads in 134.717 CPU sec, 4.247 real sec
sorting block 50, #reads = 1079431 mem = 536878590 peak = 1004269568
[M::process] read 695990 sequences (100000185 bp) in 2.576 CPU sec, 2.651 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 285022, 9, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 366, 1815)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5097)
[M::mem_pestat] mean and std.dev: (881.51, 860.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6738)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 248, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 747)
[M::mem_pestat] mean and std.dev: (272.14, 134.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 941)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 340, 763)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1857)
[M::mem_pestat] mean and std.dev: (495.20, 404.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2404)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 695538 sequences (100000139 bp) in 2.908 CPU sec, 3.006 real sec...
[M::process] read 420952 sequences (60523876 bp) in 1.491 CPU sec, 1.500 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 284985, 22, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 260, 510)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1226)
[M::mem_pestat] mean and std.dev: (289.88, 205.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1584)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 249, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 748)
[M::mem_pestat] mean and std.dev: (273.50, 135.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 942)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 819, 976)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2520)
[M::mem_pestat] mean and std.dev: (662.89, 565.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3292)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 283, 549)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1277)
[M::mem_pestat] mean and std.dev: (303.18, 177.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1641)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696478 reads in 193.603 CPU sec, 6.154 real sec
sorting block 51, #reads = 1079071 mem = 536884481 peak = 1004269568
[M::mem_process_seqs] Processed 695990 reads in 131.556 CPU sec, 4.182 real sec
sorting block 52, #reads = 1078693 mem = 536881726 peak = 1038307328
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 285815, 21, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 295, 824)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2172)
[M::mem_pestat] mean and std.dev: (471.65, 479.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2846)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 250, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 749)
[M::mem_pestat] mean and std.dev: (274.92, 136.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 943)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 332, 1077)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2805)
[M::mem_pestat] mean and std.dev: (585.45, 639.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3669)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 284, 456)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1004)
[M::mem_pestat] mean and std.dev: (313.96, 185.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1278)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 172690, 6, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 284, 672)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1710)
[M::mem_pestat] mean and std.dev: (310.41, 203.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2229)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 248, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 751)
[M::mem_pestat] mean and std.dev: (274.36, 137.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 946)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 299, 612)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1512)
[M::mem_pestat] mean and std.dev: (283.58, 151.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1962)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695538 reads in 156.206 CPU sec, 5.126 real sec
[M::mem_process_seqs] Processed 420952 reads in 87.076 CPU sec, 2.820 real sec
sorting block 53, #reads = 1079295 mem = 536876400 peak = 1038307328
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000c06f2
  features: bfebfbff 7ffefbff
  extended: f3bfb7ef fb417ffe
  amd bits: 2c100800 00000121
     brand: INTEL(R) XEON(R) PLATINUM 8559C
threads: 31
algo: bwa-mem
license: sentieon:klib=31
reads: 58130378
overall: 69895819264 mem 10434.748 user 304.685 sys 355.765 real
[main] Version: 0.7.17-r1188
[main] CMD: /opt/conda/share/sentieon-202308.03-3/libexec/bwa mem -K 100000000 -Y -R @RG\tID:A23MHWWLT4.1136_5TB-T1-TDNA-1_A23MHWWLT4_1.L008\tPU:L008\tSM:1136_5TB-T1-TDNA-1_A23MHWWLT4_1\tLB:1136_5TB-T1-TDNA-1_A23MHWWLT4_1\tDS:s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta\tPL:ILLUMINA -t 31 ./BWAIndex/Homo_sapiens_assembly38.fasta.64 0001.1136_5TB-T1-TDNA-1_A23MHWWLT4_1_R1.fastq.gz 0001.1136_5TB-T1-TDNA-1_A23MHWWLT4_1_R2.fastq.gz
[main] Real time: 355.799 sec; CPU: 10739.435 sec
sorting block 54, #reads = 149564 mem = 74576373 peak = 1038307328
uniq header count 1
merging 55 blocks
sw version: sentieon-genomics-202308.03
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000c06f2
  features: bfebfbff 7ffefbff
  extended: f3bfb7ef fb417ffe
  amd bits: 2c100800 00000121
     brand: INTEL(R) XEON(R) PLATINUM 8559C
threads: 31 max 192
algo: util-sort
license: sentieon:util=1
output file size: 3339952259
output reads: 58510645
bam_mem_sort: 55 calls 35.112 user 0.650 sys 35.872 real
bam_write: 55 calls 35.731 user 1.803 sys 45.235 real
execute: 1 calls 18.064 user 0.674 sys 380.696 real
merge_files: 1 calls 18.030 user 0.647 sys 24.742 real
parse_chunk: 867 calls 52.283 user 12.300 sys 67.910 real
read_chunk: 2343 calls 24.994 user 13.774 sys 294.275 real
sort_block: 1 calls 18.835 user 13.472 sys 285.097 real
write_chunk: 1474 calls 17.585 user 0.424 sys 23.680 real
overall: 2744971264 mem 960.505 user 41.197 sys 380.717 real
ls: cannot access '*.cram': No such file or directory