.command.log - Workdir - DAQ:SENTIEON_BWAMEM (1136_81F-T1-TDNA-1_A23MHWWLT4_1;L008;0001)

File Info

Filename: .command.log
Full Path: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/56/04b25ae715dd2396ee57c3f473ec1f/.command.log
Size: 322.5 KB
Task: DAQ:SENTIEON_BWAMEM (1136_81F-T1-TDNA-1_A23MHWWLT4_1;L008;0001)
Attempt
Content

  Downloading: s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/56/04b25ae715dd2396ee57c3f473ec1f/.command.sh
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/26/6abc3ec38b19bb2cc6b5b0e48a3618/1136_81F-T1-TDNA-1_A23MHWWLT4_1/1136_81F-T1-TDNA-1_A23MHWWLT4_1_R2.fastq.gz
  Downloading: s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta.fai
  Downloading: s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/BWAIndex
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/26/6abc3ec38b19bb2cc6b5b0e48a3618/1136_81F-T1-TDNA-1_A23MHWWLT4_1/1136_81F-T1-TDNA-1_A23MHWWLT4_1_R1.fastq.gz
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/56/04b25ae715dd2396ee57c3f473ec1f/.command.run
==> STAGING COMPLETE (7 inputs)

This software is licensed to bgold@natera.com by Sentieon Inc.
cmdline: /opt/conda/share/sentieon-202308.03-3/libexec/util sort -r Homo_sapiens_assembly38.fasta -t 31 -o 1136_81F-T1-TDNA-1_A23MHWWLT4_1.bam --sam2bam -
This software is licensed to bgold@natera.com by Sentieon Inc.
version: sentieon-genomics-202308.03
[M::bwa_idx_load_from_disk] read 3171 ALT contigs
[M::main_mem] bwa index loaded in 3258.820 CPU sec, 136.206 real sec
[M::process] read 772286 sequences (100000208 bp) in 1.240 CPU sec, 1.240 real sec...
[M::process] read 768460 sequences (100000106 bp) in 2.250 CPU sec, 2.321 real sec...
[M::process] read 769776 sequences (100000067 bp) in 2.055 CPU sec, 2.085 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 295305, 49, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 228, 645)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1627)
[M::mem_pestat] mean and std.dev: (369.21, 339.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2118)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 146, 199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 377)
[M::mem_pestat] mean and std.dev: (158.78, 65.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 466)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 603, 1574)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4408)
[M::mem_pestat] mean and std.dev: (706.83, 818.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5825)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 322, 1322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3546)
[M::mem_pestat] mean and std.dev: (608.29, 585.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4658)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 771868 sequences (100000235 bp) in 1.849 CPU sec, 1.940 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 294181, 29, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 377, 752)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1948)
[M::mem_pestat] mean and std.dev: (420.83, 348.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2546)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 203)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 387)
[M::mem_pestat] mean and std.dev: (161.50, 67.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 479)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (722, 920, 1643)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3485)
[M::mem_pestat] mean and std.dev: (1114.31, 766.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4406)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 658, 1447)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3919)
[M::mem_pestat] mean and std.dev: (857.57, 900.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5155)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 295353, 38, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 207, 631)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1599)
[M::mem_pestat] mean and std.dev: (332.44, 324.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2083)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 148, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 383)
[M::mem_pestat] mean and std.dev: (160.45, 66.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 474)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (122, 387, 1213)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3395)
[M::mem_pestat] mean and std.dev: (687.37, 703.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4486)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 253, 771)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1947)
[M::mem_pestat] mean and std.dev: (383.11, 394.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2535)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 772286 reads in 478.437 CPU sec, 15.695 real sec
[M::mem_process_seqs] Processed 768460 reads in 332.020 CPU sec, 11.085 real sec
[M::mem_process_seqs] Processed 769776 reads in 370.062 CPU sec, 12.344 real sec
sorting block 0, #reads = 1082834 mem = 536883027 peak = 546709504
[M::process] read 771778 sequences (100000008 bp) in 3.327 CPU sec, 3.646 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 295991, 32, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 335, 768)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1940)
[M::mem_pestat] mean and std.dev: (488.26, 506.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2526)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 377)
[M::mem_pestat] mean and std.dev: (158.84, 65.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 466)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (317, 709, 1743)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4595)
[M::mem_pestat] mean and std.dev: (964.47, 875.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6021)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 285, 790)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2002)
[M::mem_pestat] mean and std.dev: (459.19, 412.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2608)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 1, #reads = 1082342 mem = 536877424 peak = 678776832
[M::process] read 772184 sequences (100000251 bp) in 3.009 CPU sec, 3.250 real sec...
[M::process] read 768036 sequences (100000154 bp) in 1.832 CPU sec, 1.839 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 296131, 35, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 332, 1253)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3395)
[M::mem_pestat] mean and std.dev: (656.31, 715.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4466)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 146, 199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 377)
[M::mem_pestat] mean and std.dev: (158.69, 65.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 466)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 616, 1879)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5201)
[M::mem_pestat] mean and std.dev: (873.25, 848.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6862)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 266, 977)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2637)
[M::mem_pestat] mean and std.dev: (584.17, 617.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3467)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 771868 reads in 301.741 CPU sec, 9.685 real sec
[M::mem_process_seqs] Processed 771778 reads in 203.732 CPU sec, 6.540 real sec
sorting block 2, #reads = 1085380 mem = 536883441 peak = 678776832
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 296223, 34, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 349, 919)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2421)
[M::mem_pestat] mean and std.dev: (476.93, 462.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3172)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 146, 198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 374)
[M::mem_pestat] mean and std.dev: (158.31, 64.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 462)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (137, 358, 1070)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2936)
[M::mem_pestat] mean and std.dev: (511.21, 600.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3869)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (279, 667, 1062)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2628)
[M::mem_pestat] mean and std.dev: (724.10, 536.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3411)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 770964 sequences (100000012 bp) in 3.922 CPU sec, 4.260 real sec...
[M::process] read 771444 sequences (100000201 bp) in 1.928 CPU sec, 1.950 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 294352, 39, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 243, 796)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2094)
[M::mem_pestat] mean and std.dev: (467.46, 428.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2743)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 203)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 387)
[M::mem_pestat] mean and std.dev: (161.46, 67.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 479)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 527, 1547)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4297)
[M::mem_pestat] mean and std.dev: (836.38, 753.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5672)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 274, 1071)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2873)
[M::mem_pestat] mean and std.dev: (651.78, 681.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3774)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 772184 reads in 294.972 CPU sec, 9.434 real sec
sorting block 3, #reads = 1086555 mem = 536879538 peak = 678776832
[M::mem_process_seqs] Processed 768036 reads in 199.607 CPU sec, 6.419 real sec
sorting block 4, #reads = 1085619 mem = 536885857 peak = 678776832
[M::process] read 770524 sequences (100000139 bp) in 3.158 CPU sec, 3.377 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 295717, 28, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (137, 221, 777)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2057)
[M::mem_pestat] mean and std.dev: (426.18, 412.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2697)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 380)
[M::mem_pestat] mean and std.dev: (159.51, 65.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 470)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 430, 885)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2299)
[M::mem_pestat] mean and std.dev: (484.58, 444.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3006)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 264, 767)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1987)
[M::mem_pestat] mean and std.dev: (409.79, 362.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2597)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 769782 sequences (100000222 bp) in 2.200 CPU sec, 2.221 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 295457, 31, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 356, 1161)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3145)
[M::mem_pestat] mean and std.dev: (526.92, 506.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4137)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 380)
[M::mem_pestat] mean and std.dev: (159.66, 65.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 470)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (136, 605, 1338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3742)
[M::mem_pestat] mean and std.dev: (679.21, 664.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4944)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 306, 1389)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3785)
[M::mem_pestat] mean and std.dev: (788.27, 876.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4983)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 295518, 37, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 380, 1005)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2703)
[M::mem_pestat] mean and std.dev: (481.05, 455.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3552)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 377)
[M::mem_pestat] mean and std.dev: (158.89, 65.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 466)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 487, 1424)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3830)
[M::mem_pestat] mean and std.dev: (640.88, 681.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5033)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 533, 1441)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3879)
[M::mem_pestat] mean and std.dev: (866.33, 912.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5098)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 770964 reads in 419.471 CPU sec, 13.481 real sec
[M::mem_process_seqs] Processed 770524 reads in 326.345 CPU sec, 10.552 real sec
[M::mem_process_seqs] Processed 771444 reads in 365.137 CPU sec, 11.895 real sec
sorting block 5, #reads = 1085884 mem = 536879886 peak = 678776832
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 294877, 32, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 311, 1009)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2723)
[M::mem_pestat] mean and std.dev: (620.84, 664.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3580)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 380)
[M::mem_pestat] mean and std.dev: (159.67, 65.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 470)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (306, 823, 1858)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4962)
[M::mem_pestat] mean and std.dev: (1055.71, 995.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6514)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 336, 830)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2068)
[M::mem_pestat] mean and std.dev: (471.27, 427.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2687)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 766958 sequences (100000196 bp) in 4.206 CPU sec, 4.652 real sec...
[M::mem_process_seqs] Processed 769782 reads in 175.456 CPU sec, 5.901 real sec
sorting block 6, #reads = 1083742 mem = 536879558 peak = 678776832
[M::process] read 767194 sequences (100000111 bp) in 3.900 CPU sec, 4.199 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 293131, 46, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 433, 1314)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3506)
[M::mem_pestat] mean and std.dev: (754.68, 831.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4602)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 149, 202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 384)
[M::mem_pestat] mean and std.dev: (161.44, 66.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 475)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (274, 549, 975)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2377)
[M::mem_pestat] mean and std.dev: (495.95, 324.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3078)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 284, 836)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2142)
[M::mem_pestat] mean and std.dev: (482.00, 453.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2795)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 769040 sequences (100000075 bp) in 3.592 CPU sec, 3.886 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 293769, 27, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 409, 850)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2176)
[M::mem_pestat] mean and std.dev: (563.86, 506.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2839)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 149, 203)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 387)
[M::mem_pestat] mean and std.dev: (161.77, 67.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 479)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (323, 655, 1055)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2519)
[M::mem_pestat] mean and std.dev: (622.00, 453.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3251)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 333, 1644)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4530)
[M::mem_pestat] mean and std.dev: (754.24, 909.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5973)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 766596 sequences (100000184 bp) in 2.150 CPU sec, 2.157 real sec...
[M::mem_process_seqs] Processed 766958 reads in 313.470 CPU sec, 10.038 real sec
sorting block 7, #reads = 1083515 mem = 536884535 peak = 678776832
[M::mem_process_seqs] Processed 767194 reads in 214.959 CPU sec, 6.867 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 294329, 39, 75)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 382, 1340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3660)
[M::mem_pestat] mean and std.dev: (697.21, 732.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4820)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 381)
[M::mem_pestat] mean and std.dev: (160.20, 65.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 471)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (259, 566, 1293)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3361)
[M::mem_pestat] mean and std.dev: (774.86, 793.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4395)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 418, 1338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3700)
[M::mem_pestat] mean and std.dev: (599.88, 606.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4881)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 8, #reads = 1079893 mem = 536878978 peak = 712450048
[M::process] read 766972 sequences (100000104 bp) in 4.605 CPU sec, 4.953 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 293015, 41, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 385, 876)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2316)
[M::mem_pestat] mean and std.dev: (441.32, 444.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3036)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 149, 203)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 387)
[M::mem_pestat] mean and std.dev: (162.04, 67.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 479)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (372, 701, 1428)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3540)
[M::mem_pestat] mean and std.dev: (854.00, 655.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4596)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 367, 915)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2343)
[M::mem_pestat] mean and std.dev: (466.12, 436.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3057)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 769040 reads in 303.452 CPU sec, 9.741 real sec
[M::process] read 766814 sequences (100000121 bp) in 3.385 CPU sec, 3.481 real sec...
[M::mem_process_seqs] Processed 766596 reads in 210.288 CPU sec, 6.667 real sec
sorting block 9, #reads = 1081252 mem = 536889409 peak = 712450048
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 293411, 46, 73)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 316, 686)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1746)
[M::mem_pestat] mean and std.dev: (373.24, 301.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2276)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 149, 202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 384)
[M::mem_pestat] mean and std.dev: (161.40, 66.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 475)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (240, 620, 1264)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3312)
[M::mem_pestat] mean and std.dev: (793.80, 753.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4336)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (241, 534, 1607)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4339)
[M::mem_pestat] mean and std.dev: (845.25, 801.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5705)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 765040 sequences (100000099 bp) in 4.480 CPU sec, 4.853 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 293408, 28, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 338, 1246)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3426)
[M::mem_pestat] mean and std.dev: (646.68, 681.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4516)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 149, 203)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 387)
[M::mem_pestat] mean and std.dev: (161.98, 67.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 479)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (114, 303, 710)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1902)
[M::mem_pestat] mean and std.dev: (340.92, 334.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2498)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 287, 739)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1857)
[M::mem_pestat] mean and std.dev: (426.38, 375.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2416)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 766520 sequences (100000194 bp) in 2.750 CPU sec, 2.751 real sec...
[M::mem_process_seqs] Processed 766972 reads in 299.198 CPU sec, 9.549 real sec
sorting block 10, #reads = 1080215 mem = 536879431 peak = 712450048
[M::mem_process_seqs] Processed 766814 reads in 206.718 CPU sec, 6.587 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 292894, 40, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (131, 359, 739)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1955)
[M::mem_pestat] mean and std.dev: (438.71, 397.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2563)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (112, 150, 204)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 388)
[M::mem_pestat] mean and std.dev: (162.90, 67.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 480)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (241, 518, 803)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1927)
[M::mem_pestat] mean and std.dev: (575.89, 456.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2489)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 283, 1298)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3566)
[M::mem_pestat] mean and std.dev: (602.59, 579.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4700)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 11, #reads = 1080220 mem = 536878660 peak = 712450048
[M::process] read 767186 sequences (100000071 bp) in 4.733 CPU sec, 5.105 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 293240, 47, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 258, 699)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1753)
[M::mem_pestat] mean and std.dev: (366.84, 322.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2280)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 149, 203)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 387)
[M::mem_pestat] mean and std.dev: (162.00, 67.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 479)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (105, 527, 1310)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3720)
[M::mem_pestat] mean and std.dev: (948.26, 1124.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5447)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 569, 1242)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3322)
[M::mem_pestat] mean and std.dev: (712.00, 626.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4362)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 765040 reads in 281.190 CPU sec, 8.989 real sec
[M::process] read 765658 sequences (100000125 bp) in 3.302 CPU sec, 3.380 real sec...
[M::mem_process_seqs] Processed 766520 reads in 191.026 CPU sec, 6.072 real sec
sorting block 12, #reads = 1082552 mem = 536880929 peak = 712450048
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (77, 293228, 29, 95)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 311, 769)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1937)
[M::mem_pestat] mean and std.dev: (444.08, 397.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2521)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 149, 202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 384)
[M::mem_pestat] mean and std.dev: (161.14, 66.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 475)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (249, 628, 2334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6504)
[M::mem_pestat] mean and std.dev: (896.12, 1073.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8589)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 293, 641)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1569)
[M::mem_pestat] mean and std.dev: (354.85, 275.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2033)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 767704 sequences (100000225 bp) in 4.259 CPU sec, 4.557 real sec...
[M::process] read 767808 sequences (100000214 bp) in 2.280 CPU sec, 2.275 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 292993, 30, 80)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 292, 1246)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3346)
[M::mem_pestat] mean and std.dev: (636.75, 606.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4396)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (112, 150, 204)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 388)
[M::mem_pestat] mean and std.dev: (162.41, 67.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 480)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (526, 681, 2681)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6991)
[M::mem_pestat] mean and std.dev: (1651.43, 1755.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9146)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 331, 741)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1867)
[M::mem_pestat] mean and std.dev: (469.31, 392.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2430)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 767186 reads in 274.113 CPU sec, 8.769 real sec
sorting block 13, #reads = 1080088 mem = 536887589 peak = 712450048
[M::mem_process_seqs] Processed 765658 reads in 185.361 CPU sec, 5.938 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 293285, 44, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (135, 426, 977)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2661)
[M::mem_pestat] mean and std.dev: (524.69, 550.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3503)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 149, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 381)
[M::mem_pestat] mean and std.dev: (160.86, 66.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 471)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (73, 507, 1068)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3058)
[M::mem_pestat] mean and std.dev: (521.17, 602.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4053)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 301, 653)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1615)
[M::mem_pestat] mean and std.dev: (439.03, 348.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2096)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 767636 sequences (100000067 bp) in 3.774 CPU sec, 4.079 real sec...
sorting block 14, #reads = 1081743 mem = 536878199 peak = 712450048
[M::process] read 770770 sequences (100000172 bp) in 2.705 CPU sec, 2.717 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 293801, 41, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 305, 1025)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2713)
[M::mem_pestat] mean and std.dev: (595.21, 636.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3557)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 384)
[M::mem_pestat] mean and std.dev: (161.04, 66.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 475)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (130, 443, 1620)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4600)
[M::mem_pestat] mean and std.dev: (899.12, 983.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6090)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 299, 881)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2319)
[M::mem_pestat] mean and std.dev: (529.63, 508.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3038)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 767704 reads in 303.510 CPU sec, 9.993 real sec
[M::mem_process_seqs] Processed 767808 reads in 205.859 CPU sec, 6.591 real sec
sorting block 15, #reads = 1081841 mem = 536888603 peak = 712450048
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (77, 293636, 32, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 304, 800)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2068)
[M::mem_pestat] mean and std.dev: (449.14, 441.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2702)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 149, 202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 384)
[M::mem_pestat] mean and std.dev: (161.31, 66.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 475)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (248, 678, 1300)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3404)
[M::mem_pestat] mean and std.dev: (774.55, 746.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4456)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 473, 1010)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2644)
[M::mem_pestat] mean and std.dev: (590.08, 466.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3461)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 770382 sequences (100000090 bp) in 4.186 CPU sec, 4.455 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 294811, 50, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 483, 1295)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3499)
[M::mem_pestat] mean and std.dev: (837.36, 1034.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4974)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 380)
[M::mem_pestat] mean and std.dev: (159.73, 66.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 470)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (307, 631, 1265)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3181)
[M::mem_pestat] mean and std.dev: (630.31, 618.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4139)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (256, 728, 1931)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5281)
[M::mem_pestat] mean and std.dev: (1038.98, 971.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6956)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 770062 sequences (100000153 bp) in 2.833 CPU sec, 2.838 real sec...
[M::mem_process_seqs] Processed 767636 reads in 303.434 CPU sec, 9.704 real sec
[M::mem_process_seqs] Processed 770770 reads in 207.215 CPU sec, 6.624 real sec
sorting block 16, #reads = 1081304 mem = 536880106 peak = 712450048
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 295613, 31, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (140, 239, 568)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1424)
[M::mem_pestat] mean and std.dev: (333.27, 263.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1852)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 383)
[M::mem_pestat] mean and std.dev: (160.20, 66.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 474)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (100, 295, 1514)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4342)
[M::mem_pestat] mean and std.dev: (697.48, 858.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5756)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 324, 750)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1870)
[M::mem_pestat] mean and std.dev: (427.80, 349.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2430)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 771314 sequences (100000202 bp) in 4.575 CPU sec, 4.915 real sec...
sorting block 17, #reads = 1082842 mem = 536881771 peak = 712450048
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 294993, 26, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 446, 1533)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4185)
[M::mem_pestat] mean and std.dev: (803.61, 784.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5511)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 148, 202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 386)
[M::mem_pestat] mean and std.dev: (160.86, 67.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 478)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 752, 3149)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9049)
[M::mem_pestat] mean and std.dev: (1894.19, 2506.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11999)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (239, 336, 445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 857)
[M::mem_pestat] mean and std.dev: (311.51, 157.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1063)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 771028 sequences (100000031 bp) in 2.849 CPU sec, 2.855 real sec...
[M::mem_process_seqs] Processed 770382 reads in 290.672 CPU sec, 9.287 real sec
[M::mem_process_seqs] Processed 770062 reads in 190.024 CPU sec, 6.068 real sec
sorting block 18, #reads = 1085967 mem = 536880279 peak = 712450048
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 295321, 39, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 238, 937)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2489)
[M::mem_pestat] mean and std.dev: (472.33, 519.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3265)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 380)
[M::mem_pestat] mean and std.dev: (159.50, 66.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 470)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 526, 978)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2570)
[M::mem_pestat] mean and std.dev: (598.97, 463.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3366)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 255, 1246)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3412)
[M::mem_pestat] mean and std.dev: (573.90, 582.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4495)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 770294 sequences (100000117 bp) in 4.513 CPU sec, 4.850 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 295917, 35, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 297, 1051)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2799)
[M::mem_pestat] mean and std.dev: (545.77, 583.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3673)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 380)
[M::mem_pestat] mean and std.dev: (159.55, 65.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 470)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (444, 564, 2061)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5295)
[M::mem_pestat] mean and std.dev: (1035.52, 927.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6912)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 447, 1355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3649)
[M::mem_pestat] mean and std.dev: (747.63, 802.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4796)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 769864 sequences (100000183 bp) in 2.390 CPU sec, 2.384 real sec...
[M::mem_process_seqs] Processed 771314 reads in 287.117 CPU sec, 9.315 real sec
[M::mem_process_seqs] Processed 771028 reads in 190.111 CPU sec, 6.077 real sec
sorting block 19, #reads = 1085318 mem = 536879594 peak = 712450048
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 296558, 35, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 266, 432)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 894)
[M::mem_pestat] mean and std.dev: (259.11, 122.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1125)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 383)
[M::mem_pestat] mean and std.dev: (160.24, 66.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 474)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (300, 357, 1219)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3057)
[M::mem_pestat] mean and std.dev: (667.62, 615.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3976)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 418, 1016)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2718)
[M::mem_pestat] mean and std.dev: (464.97, 429.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3569)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 768896 sequences (100000203 bp) in 3.850 CPU sec, 4.152 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 295945, 34, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 272, 621)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1547)
[M::mem_pestat] mean and std.dev: (342.35, 299.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2010)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 148, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 383)
[M::mem_pestat] mean and std.dev: (160.29, 66.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 474)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (43, 592, 1170)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3424)
[M::mem_pestat] mean and std.dev: (521.11, 628.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4551)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (143, 285, 1356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3782)
[M::mem_pestat] mean and std.dev: (750.75, 871.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4995)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 770294 reads in 279.313 CPU sec, 8.940 real sec
[M::process] read 770802 sequences (100000155 bp) in 3.110 CPU sec, 3.115 real sec...
sorting block 20, #reads = 1087424 mem = 536881562 peak = 712450048
[M::mem_process_seqs] Processed 769864 reads in 191.302 CPU sec, 6.096 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 295247, 28, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (128, 193, 644)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1676)
[M::mem_pestat] mean and std.dev: (318.02, 328.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2192)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 384)
[M::mem_pestat] mean and std.dev: (161.01, 67.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 475)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 606, 1218)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3230)
[M::mem_pestat] mean and std.dev: (731.04, 663.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4236)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 315, 753)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1843)
[M::mem_pestat] mean and std.dev: (462.24, 375.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2388)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 21, #reads = 1086617 mem = 536881446 peak = 712450048
[M::process] read 770042 sequences (100000155 bp) in 5.357 CPU sec, 5.730 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 295760, 39, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 263, 1183)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3217)
[M::mem_pestat] mean and std.dev: (538.59, 677.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4234)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 380)
[M::mem_pestat] mean and std.dev: (159.63, 66.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 470)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (140, 312, 979)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2657)
[M::mem_pestat] mean and std.dev: (483.97, 464.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3496)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 360, 1616)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4476)
[M::mem_pestat] mean and std.dev: (730.56, 841.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5906)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 768896 reads in 291.586 CPU sec, 9.355 real sec
[M::process] read 769634 sequences (100000199 bp) in 3.382 CPU sec, 3.467 real sec...
[M::mem_process_seqs] Processed 770802 reads in 202.921 CPU sec, 6.470 real sec
sorting block 22, #reads = 1086215 mem = 536878239 peak = 712450048
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 295418, 27, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 418, 750)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1870)
[M::mem_pestat] mean and std.dev: (521.69, 436.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2430)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 148, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 383)
[M::mem_pestat] mean and std.dev: (160.12, 66.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 474)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (298, 524, 977)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2335)
[M::mem_pestat] mean and std.dev: (575.56, 483.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3014)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (234, 507, 1155)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2997)
[M::mem_pestat] mean and std.dev: (671.08, 644.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3918)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 768394 sequences (100000263 bp) in 4.787 CPU sec, 5.116 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 295073, 49, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 256, 883)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2325)
[M::mem_pestat] mean and std.dev: (485.60, 448.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3046)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 148, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 383)
[M::mem_pestat] mean and std.dev: (160.30, 66.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 474)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 412, 1315)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3589)
[M::mem_pestat] mean and std.dev: (755.90, 802.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4726)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (125, 264, 994)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2732)
[M::mem_pestat] mean and std.dev: (564.48, 637.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3601)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 770042 reads in 283.548 CPU sec, 9.302 real sec
[M::mem_process_seqs] Processed 769634 reads in 196.662 CPU sec, 6.267 real sec
sorting block 23, #reads = 1085520 mem = 536880979 peak = 712450048
[M::process] read 765374 sequences (100000140 bp) in 3.428 CPU sec, 3.645 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 294097, 41, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 324, 1371)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3785)
[M::mem_pestat] mean and std.dev: (708.81, 773.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4992)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 384)
[M::mem_pestat] mean and std.dev: (161.09, 66.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 475)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (227, 436, 1601)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4349)
[M::mem_pestat] mean and std.dev: (756.75, 963.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5723)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 361, 834)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2094)
[M::mem_pestat] mean and std.dev: (502.02, 440.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2724)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 24, #reads = 1085466 mem = 536880770 peak = 712450048
[M::process] read 767766 sequences (100000257 bp) in 4.101 CPU sec, 4.428 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 293513, 45, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 309, 990)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2620)
[M::mem_pestat] mean and std.dev: (609.34, 621.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3435)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (112, 150, 205)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 391)
[M::mem_pestat] mean and std.dev: (163.37, 68.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 484)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (259, 638, 1062)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2668)
[M::mem_pestat] mean and std.dev: (659.40, 512.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3471)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 247, 647)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1599)
[M::mem_pestat] mean and std.dev: (370.24, 325.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2075)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 768394 reads in 284.097 CPU sec, 9.144 real sec
[M::process] read 767614 sequences (100000151 bp) in 3.240 CPU sec, 3.343 real sec...
[M::mem_process_seqs] Processed 765374 reads in 200.118 CPU sec, 6.362 real sec
sorting block 25, #reads = 1083459 mem = 536880377 peak = 712450048
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 293694, 44, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 289, 806)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2064)
[M::mem_pestat] mean and std.dev: (497.63, 502.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2693)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 149, 202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 384)
[M::mem_pestat] mean and std.dev: (161.15, 66.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 475)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 588, 1838)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5052)
[M::mem_pestat] mean and std.dev: (960.15, 1097.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6659)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (236, 522, 989)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2495)
[M::mem_pestat] mean and std.dev: (603.53, 483.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3248)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 768562 sequences (100000075 bp) in 4.021 CPU sec, 4.402 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (74, 293707, 34, 73)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 386, 1023)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2679)
[M::mem_pestat] mean and std.dev: (487.62, 484.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3507)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 149, 202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 384)
[M::mem_pestat] mean and std.dev: (161.16, 66.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 475)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (238, 607, 1139)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2941)
[M::mem_pestat] mean and std.dev: (502.63, 348.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3842)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 541, 989)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2581)
[M::mem_pestat] mean and std.dev: (635.00, 563.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3377)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 767766 reads in 285.061 CPU sec, 9.476 real sec
[M::process] read 767884 sequences (100000174 bp) in 3.107 CPU sec, 3.159 real sec...
[M::mem_process_seqs] Processed 767614 reads in 198.566 CPU sec, 6.323 real sec
sorting block 26, #reads = 1082298 mem = 536876201 peak = 712450048
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 293951, 37, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 502, 1116)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2964)
[M::mem_pestat] mean and std.dev: (648.95, 647.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3888)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 381)
[M::mem_pestat] mean and std.dev: (160.49, 66.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 471)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (97, 366, 996)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2794)
[M::mem_pestat] mean and std.dev: (546.89, 556.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3693)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 346, 759)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1951)
[M::mem_pestat] mean and std.dev: (437.44, 368.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2547)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 27, #reads = 1082513 mem = 536881057 peak = 712450048
[M::process] read 766698 sequences (100000177 bp) in 4.024 CPU sec, 4.333 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 293861, 42, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 571, 1132)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3040)
[M::mem_pestat] mean and std.dev: (727.08, 726.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3994)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 381)
[M::mem_pestat] mean and std.dev: (160.64, 66.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 471)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (284, 813, 1019)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2489)
[M::mem_pestat] mean and std.dev: (597.25, 389.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3224)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 332, 836)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2136)
[M::mem_pestat] mean and std.dev: (508.72, 525.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2786)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 765734 sequences (100000173 bp) in 2.709 CPU sec, 2.702 real sec...
[M::mem_process_seqs] Processed 768562 reads in 282.258 CPU sec, 9.019 real sec
[M::mem_process_seqs] Processed 767884 reads in 193.403 CPU sec, 6.145 real sec
sorting block 28, #reads = 1080980 mem = 536881958 peak = 712450048
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (73, 293280, 27, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (137, 271, 700)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1826)
[M::mem_pestat] mean and std.dev: (388.88, 371.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2389)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 149, 203)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 387)
[M::mem_pestat] mean and std.dev: (161.80, 67.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 479)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (428, 954, 2466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6542)
[M::mem_pestat] mean and std.dev: (1362.96, 1360.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8580)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (236, 422, 969)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2435)
[M::mem_pestat] mean and std.dev: (621.64, 532.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3168)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 767924 sequences (100000164 bp) in 3.804 CPU sec, 4.067 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 292751, 49, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 345, 1120)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3046)
[M::mem_pestat] mean and std.dev: (520.40, 552.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4009)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (112, 149, 204)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 388)
[M::mem_pestat] mean and std.dev: (162.57, 67.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 480)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 432, 1327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3667)
[M::mem_pestat] mean and std.dev: (698.70, 842.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4837)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (250, 525, 1101)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2803)
[M::mem_pestat] mean and std.dev: (758.63, 703.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3654)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 768452 sequences (100000192 bp) in 2.659 CPU sec, 2.653 real sec...
[M::mem_process_seqs] Processed 766698 reads in 276.516 CPU sec, 8.828 real sec
sorting block 29, #reads = 1081863 mem = 536878742 peak = 712450048
[M::mem_process_seqs] Processed 765734 reads in 194.313 CPU sec, 6.180 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 293410, 57, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 344, 1157)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3127)
[M::mem_pestat] mean and std.dev: (652.34, 730.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4112)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 381)
[M::mem_pestat] mean and std.dev: (160.64, 66.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 471)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (259, 540, 1628)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4366)
[M::mem_pestat] mean and std.dev: (774.57, 901.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5735)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 370, 938)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2446)
[M::mem_pestat] mean and std.dev: (557.97, 556.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3200)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 768064 sequences (100000073 bp) in 3.965 CPU sec, 4.232 real sec...
[M::process] read 769070 sequences (100000075 bp) in 2.897 CPU sec, 2.906 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 293909, 36, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 551, 999)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2661)
[M::mem_pestat] mean and std.dev: (641.39, 569.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3492)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 381)
[M::mem_pestat] mean and std.dev: (160.57, 66.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 471)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 481, 873)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2251)
[M::mem_pestat] mean and std.dev: (420.87, 387.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2940)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 447, 1534)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4208)
[M::mem_pestat] mean and std.dev: (868.26, 1077.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5545)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 767924 reads in 287.554 CPU sec, 9.711 real sec
sorting block 30, #reads = 1080706 mem = 536879470 peak = 712450048
[M::mem_process_seqs] Processed 768452 reads in 194.686 CPU sec, 6.202 real sec
sorting block 31, #reads = 1080132 mem = 536882373 peak = 747048960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 294179, 27, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 333, 1365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3775)
[M::mem_pestat] mean and std.dev: (591.62, 751.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4980)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 381)
[M::mem_pestat] mean and std.dev: (160.85, 66.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 471)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (96, 508, 1385)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3963)
[M::mem_pestat] mean and std.dev: (722.80, 802.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5252)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 294, 845)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2191)
[M::mem_pestat] mean and std.dev: (547.07, 564.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2864)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 768732 sequences (100000117 bp) in 4.028 CPU sec, 4.285 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 294368, 36, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 221, 556)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1374)
[M::mem_pestat] mean and std.dev: (295.49, 257.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1783)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 147, 200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 378)
[M::mem_pestat] mean and std.dev: (159.91, 65.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 467)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (262, 662, 1784)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4828)
[M::mem_pestat] mean and std.dev: (937.12, 907.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6350)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 573, 1117)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2967)
[M::mem_pestat] mean and std.dev: (770.75, 811.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4017)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 770080 sequences (100000159 bp) in 2.829 CPU sec, 2.829 real sec...
[M::mem_process_seqs] Processed 768064 reads in 281.947 CPU sec, 9.003 real sec
[M::mem_process_seqs] Processed 769070 reads in 214.673 CPU sec, 6.877 real sec
sorting block 32, #reads = 1083522 mem = 536882715 peak = 747048960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (77, 293922, 35, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 335, 1027)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2767)
[M::mem_pestat] mean and std.dev: (526.66, 572.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3637)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 381)
[M::mem_pestat] mean and std.dev: (160.34, 65.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 471)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (241, 472, 848)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2062)
[M::mem_pestat] mean and std.dev: (498.00, 454.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2669)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 289, 618)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1506)
[M::mem_pestat] mean and std.dev: (401.07, 312.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1950)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 772622 sequences (100000059 bp) in 4.257 CPU sec, 4.536 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 295145, 33, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 288, 1141)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3119)
[M::mem_pestat] mean and std.dev: (555.00, 647.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4108)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 380)
[M::mem_pestat] mean and std.dev: (159.84, 65.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 470)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (314, 617, 1675)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4397)
[M::mem_pestat] mean and std.dev: (941.76, 926.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5758)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 446, 1283)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3503)
[M::mem_pestat] mean and std.dev: (764.15, 791.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4613)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 771308 sequences (100000291 bp) in 2.779 CPU sec, 2.786 real sec...
[M::mem_process_seqs] Processed 768732 reads in 285.286 CPU sec, 9.091 real sec
sorting block 33, #reads = 1081936 mem = 536883491 peak = 747048960
[M::mem_process_seqs] Processed 770080 reads in 200.697 CPU sec, 6.395 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 295763, 43, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (130, 315, 707)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1861)
[M::mem_pestat] mean and std.dev: (387.33, 334.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2438)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 146, 199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 379)
[M::mem_pestat] mean and std.dev: (159.03, 66.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 469)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (313, 581, 1289)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3241)
[M::mem_pestat] mean and std.dev: (599.61, 543.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4217)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 356, 1117)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2923)
[M::mem_pestat] mean and std.dev: (680.77, 684.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3826)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 34, #reads = 1078884 mem = 536884043 peak = 747048960
[M::process] read 771070 sequences (100000000 bp) in 4.871 CPU sec, 5.152 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 295281, 36, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 393, 1182)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3238)
[M::mem_pestat] mean and std.dev: (607.54, 637.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4266)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 377)
[M::mem_pestat] mean and std.dev: (159.19, 65.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 466)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (263, 756, 1486)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3932)
[M::mem_pestat] mean and std.dev: (884.79, 827.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5155)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 294, 533)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1299)
[M::mem_pestat] mean and std.dev: (311.94, 218.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1682)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 770116 sequences (100000203 bp) in 2.842 CPU sec, 2.844 real sec...
[M::mem_process_seqs] Processed 772622 reads in 288.679 CPU sec, 9.182 real sec
[M::mem_process_seqs] Processed 771308 reads in 202.199 CPU sec, 6.441 real sec
sorting block 35, #reads = 1082685 mem = 536882448 peak = 747048960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 295191, 38, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (144, 253, 479)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1149)
[M::mem_pestat] mean and std.dev: (319.82, 226.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1484)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 380)
[M::mem_pestat] mean and std.dev: (159.72, 66.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 470)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 355, 689)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1733)
[M::mem_pestat] mean and std.dev: (412.51, 376.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2255)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 340, 664)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1566)
[M::mem_pestat] mean and std.dev: (419.67, 355.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2017)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 769438 sequences (100000071 bp) in 3.913 CPU sec, 4.164 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 295683, 25, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 292, 552)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1238)
[M::mem_pestat] mean and std.dev: (374.16, 273.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1581)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 148, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 383)
[M::mem_pestat] mean and std.dev: (160.44, 66.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 474)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (330, 422, 632)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1236)
[M::mem_pestat] mean and std.dev: (457.61, 192.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1538)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (249, 394, 987)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2463)
[M::mem_pestat] mean and std.dev: (672.35, 645.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3253)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 767376 sequences (100000148 bp) in 2.963 CPU sec, 2.967 real sec...
[M::mem_process_seqs] Processed 771070 reads in 291.858 CPU sec, 9.871 real sec
sorting block 36, #reads = 1081822 mem = 536879717 peak = 747048960
[M::mem_process_seqs] Processed 770116 reads in 200.577 CPU sec, 6.421 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 295461, 41, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 362, 987)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2523)
[M::mem_pestat] mean and std.dev: (528.25, 475.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3291)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 148, 202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 386)
[M::mem_pestat] mean and std.dev: (160.91, 67.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 478)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 422, 1310)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3636)
[M::mem_pestat] mean and std.dev: (645.41, 750.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4799)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 230, 993)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2609)
[M::mem_pestat] mean and std.dev: (438.19, 460.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3417)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 771044 sequences (100000145 bp) in 3.865 CPU sec, 4.094 real sec...
sorting block 37, #reads = 1085866 mem = 536879142 peak = 747048960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 294394, 28, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (144, 215, 795)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2097)
[M::mem_pestat] mean and std.dev: (431.10, 442.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2748)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 149, 203)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 387)
[M::mem_pestat] mean and std.dev: (162.15, 67.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 479)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (127, 570, 1182)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3292)
[M::mem_pestat] mean and std.dev: (728.04, 719.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4347)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 481, 1076)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2836)
[M::mem_pestat] mean and std.dev: (645.18, 594.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3716)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 771064 sequences (100000157 bp) in 2.621 CPU sec, 2.632 real sec...
[M::mem_process_seqs] Processed 769438 reads in 280.642 CPU sec, 8.961 real sec
[M::mem_process_seqs] Processed 767376 reads in 195.956 CPU sec, 6.250 real sec
sorting block 38, #reads = 1086096 mem = 536876985 peak = 747048960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 296364, 32, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 266, 497)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1187)
[M::mem_pestat] mean and std.dev: (288.67, 220.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1532)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 380)
[M::mem_pestat] mean and std.dev: (159.63, 66.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 470)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (362, 964, 7567)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 21977)
[M::mem_pestat] mean and std.dev: (2623.47, 3287.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 29182)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 338, 948)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2520)
[M::mem_pestat] mean and std.dev: (449.34, 465.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3306)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 770858 sequences (100000292 bp) in 4.331 CPU sec, 4.526 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 295886, 48, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 255, 449)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1019)
[M::mem_pestat] mean and std.dev: (259.64, 156.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1304)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 380)
[M::mem_pestat] mean and std.dev: (159.47, 65.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 470)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (295, 691, 1563)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4099)
[M::mem_pestat] mean and std.dev: (887.84, 923.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5367)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 362, 765)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1857)
[M::mem_pestat] mean and std.dev: (474.57, 346.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2403)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 770216 sequences (100000077 bp) in 3.099 CPU sec, 3.108 real sec...
[M::mem_process_seqs] Processed 771044 reads in 275.178 CPU sec, 8.767 real sec
sorting block 39, #reads = 1084039 mem = 536882217 peak = 747048960
[M::mem_process_seqs] Processed 771064 reads in 193.474 CPU sec, 6.155 real sec
sorting block 40, #reads = 1087283 mem = 536879590 peak = 747048960
[M::process] read 770672 sequences (100000110 bp) in 4.151 CPU sec, 4.424 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 295516, 39, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 221, 388)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 802)
[M::mem_pestat] mean and std.dev: (260.09, 152.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1009)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 383)
[M::mem_pestat] mean and std.dev: (160.15, 66.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 474)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (225, 953, 1546)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4188)
[M::mem_pestat] mean and std.dev: (1065.24, 1051.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5509)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 298, 789)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1983)
[M::mem_pestat] mean and std.dev: (447.31, 423.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2580)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 768250 sequences (100000250 bp) in 2.933 CPU sec, 2.934 real sec...
[M::mem_process_seqs] Processed 770216 reads in 165.473 CPU sec, 5.249 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 295506, 55, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 449, 923)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2441)
[M::mem_pestat] mean and std.dev: (598.51, 617.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3200)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 380)
[M::mem_pestat] mean and std.dev: (159.88, 66.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 470)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 559, 1535)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4171)
[M::mem_pestat] mean and std.dev: (939.21, 1024.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5489)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 372, 1417)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3903)
[M::mem_pestat] mean and std.dev: (761.88, 905.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5146)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 295290, 40, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 318, 621)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1489)
[M::mem_pestat] mean and std.dev: (377.12, 270.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1923)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 380)
[M::mem_pestat] mean and std.dev: (159.53, 65.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 470)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 587, 1508)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4100)
[M::mem_pestat] mean and std.dev: (721.50, 737.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5396)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 668, 1529)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4205)
[M::mem_pestat] mean and std.dev: (863.61, 936.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5543)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 770858 reads in 434.732 CPU sec, 13.861 real sec
[M::process] read 766868 sequences (100000083 bp) in 3.471 CPU sec, 3.495 real sec...
sorting block 41, #reads = 1084765 mem = 536890305 peak = 747048960
[M::mem_process_seqs] Processed 770672 reads in 232.732 CPU sec, 7.425 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 294676, 45, 76)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 438, 1298)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3520)
[M::mem_pestat] mean and std.dev: (572.11, 537.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4631)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 203)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 387)
[M::mem_pestat] mean and std.dev: (161.59, 67.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 479)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (403, 1070, 3005)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8209)
[M::mem_pestat] mean and std.dev: (1989.66, 2491.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11956)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 303, 838)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2136)
[M::mem_pestat] mean and std.dev: (462.33, 419.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2785)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 42, #reads = 1085531 mem = 536889421 peak = 747048960
[M::process] read 768924 sequences (100000124 bp) in 4.905 CPU sec, 5.231 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 293844, 43, 75)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 396, 712)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1802)
[M::mem_pestat] mean and std.dev: (415.02, 329.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2347)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (112, 150, 205)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 391)
[M::mem_pestat] mean and std.dev: (162.93, 68.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 484)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (372, 864, 2028)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5340)
[M::mem_pestat] mean and std.dev: (1131.65, 1115.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6996)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 357, 770)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1956)
[M::mem_pestat] mean and std.dev: (450.97, 360.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2549)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 768250 reads in 267.020 CPU sec, 8.503 real sec
[M::process] read 768144 sequences (100000016 bp) in 2.920 CPU sec, 2.962 real sec...
[M::mem_process_seqs] Processed 766868 reads in 202.281 CPU sec, 6.465 real sec
sorting block 43, #reads = 1083504 mem = 536879881 peak = 747048960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 294575, 45, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 282, 1414)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3920)
[M::mem_pestat] mean and std.dev: (760.67, 943.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5173)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 384)
[M::mem_pestat] mean and std.dev: (160.82, 66.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 475)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (135, 512, 1371)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3843)
[M::mem_pestat] mean and std.dev: (685.83, 751.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5079)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 414, 764)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1908)
[M::mem_pestat] mean and std.dev: (429.20, 318.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2480)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 767902 sequences (100000108 bp) in 4.304 CPU sec, 4.627 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 294371, 41, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 410, 1105)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2903)
[M::mem_pestat] mean and std.dev: (636.26, 650.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3802)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 384)
[M::mem_pestat] mean and std.dev: (160.97, 66.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 475)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 723, 1244)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3410)
[M::mem_pestat] mean and std.dev: (699.44, 670.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4493)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (257, 404, 920)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2246)
[M::mem_pestat] mean and std.dev: (521.15, 437.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2909)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 767816 sequences (100000146 bp) in 2.003 CPU sec, 2.012 real sec...
[M::mem_process_seqs] Processed 768924 reads in 278.627 CPU sec, 8.907 real sec
[M::mem_process_seqs] Processed 768144 reads in 190.486 CPU sec, 6.092 real sec
sorting block 44, #reads = 1082713 mem = 536878727 peak = 747048960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 293952, 36, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (138, 368, 529)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1311)
[M::mem_pestat] mean and std.dev: (350.44, 249.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1702)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 149, 202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 384)
[M::mem_pestat] mean and std.dev: (161.04, 66.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 475)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 667, 1662)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4666)
[M::mem_pestat] mean and std.dev: (1053.76, 1262.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6168)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 327, 867)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2247)
[M::mem_pestat] mean and std.dev: (519.30, 492.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2937)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 767652 sequences (100000009 bp) in 4.152 CPU sec, 4.443 real sec...
sorting block 45, #reads = 1084345 mem = 536880770 peak = 747048960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 294048, 59, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (145, 253, 883)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2359)
[M::mem_pestat] mean and std.dev: (469.13, 541.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3097)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 149, 202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 384)
[M::mem_pestat] mean and std.dev: (161.18, 66.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 475)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (113, 654, 1272)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3590)
[M::mem_pestat] mean and std.dev: (694.23, 673.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4749)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 234, 612)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1466)
[M::mem_pestat] mean and std.dev: (330.32, 250.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1893)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 768624 sequences (100000056 bp) in 2.803 CPU sec, 2.811 real sec...
[M::mem_process_seqs] Processed 767902 reads in 285.524 CPU sec, 9.234 real sec
[M::mem_process_seqs] Processed 767816 reads in 193.654 CPU sec, 6.182 real sec
sorting block 46, #reads = 1085195 mem = 536885871 peak = 747048960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 293390, 36, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 229, 719)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1813)
[M::mem_pestat] mean and std.dev: (371.54, 331.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2360)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 149, 202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 384)
[M::mem_pestat] mean and std.dev: (161.03, 66.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 475)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (335, 720, 1464)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3722)
[M::mem_pestat] mean and std.dev: (918.94, 726.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4851)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 289, 753)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1911)
[M::mem_pestat] mean and std.dev: (391.42, 303.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2490)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 768446 sequences (100000058 bp) in 4.487 CPU sec, 4.821 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 293817, 31, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 309, 991)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2617)
[M::mem_pestat] mean and std.dev: (596.49, 608.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3430)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 381)
[M::mem_pestat] mean and std.dev: (160.51, 66.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 471)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 683, 1882)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5272)
[M::mem_pestat] mean and std.dev: (817.21, 792.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6967)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 310, 925)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2403)
[M::mem_pestat] mean and std.dev: (446.27, 414.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3142)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 767916 sequences (100000139 bp) in 2.019 CPU sec, 2.021 real sec...
[M::mem_process_seqs] Processed 767652 reads in 291.393 CPU sec, 9.347 real sec
[M::mem_process_seqs] Processed 768624 reads in 195.473 CPU sec, 6.251 real sec
sorting block 47, #reads = 1081837 mem = 536887750 peak = 747048960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 294301, 21, 75)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (137, 200, 1417)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3977)
[M::mem_pestat] mean and std.dev: (693.49, 950.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5257)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 381)
[M::mem_pestat] mean and std.dev: (160.44, 66.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 471)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (418, 666, 1380)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3304)
[M::mem_pestat] mean and std.dev: (738.89, 541.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4266)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 386, 1970)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5484)
[M::mem_pestat] mean and std.dev: (839.63, 1220.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7241)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 768382 sequences (100000003 bp) in 4.707 CPU sec, 4.995 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 292743, 36, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 284, 907)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2355)
[M::mem_pestat] mean and std.dev: (537.21, 561.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3079)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 381)
[M::mem_pestat] mean and std.dev: (160.82, 66.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 471)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (278, 578, 1107)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2765)
[M::mem_pestat] mean and std.dev: (665.12, 610.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3594)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 280, 1161)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3133)
[M::mem_pestat] mean and std.dev: (596.52, 668.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4119)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 767960 sequences (100000042 bp) in 2.590 CPU sec, 2.597 real sec...
[M::mem_process_seqs] Processed 768446 reads in 283.862 CPU sec, 9.055 real sec
sorting block 48, #reads = 1080377 mem = 536884188 peak = 747048960
[M::mem_process_seqs] Processed 767916 reads in 196.157 CPU sec, 6.263 real sec
sorting block 49, #reads = 1083144 mem = 536878370 peak = 747048960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 293739, 38, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 364, 911)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2337)
[M::mem_pestat] mean and std.dev: (507.91, 460.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3050)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 381)
[M::mem_pestat] mean and std.dev: (160.63, 66.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 471)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (98, 492, 1012)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2840)
[M::mem_pestat] mean and std.dev: (548.29, 641.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3754)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 253, 481)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1125)
[M::mem_pestat] mean and std.dev: (285.17, 216.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1447)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 768434 sequences (100000054 bp) in 4.036 CPU sec, 4.305 real sec...
[M::process] read 769990 sequences (100000102 bp) in 2.504 CPU sec, 2.511 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 294121, 38, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 307, 1036)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2782)
[M::mem_pestat] mean and std.dev: (554.53, 620.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3655)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 381)
[M::mem_pestat] mean and std.dev: (160.61, 66.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 471)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (302, 1038, 1843)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4925)
[M::mem_pestat] mean and std.dev: (972.12, 770.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6466)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 291, 891)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2357)
[M::mem_pestat] mean and std.dev: (422.70, 421.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3090)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 768382 reads in 287.929 CPU sec, 9.681 real sec
[M::mem_process_seqs] Processed 767960 reads in 192.789 CPU sec, 6.153 real sec
sorting block 50, #reads = 1082827 mem = 536878331 peak = 747048960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 293902, 31, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 543, 1159)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3127)
[M::mem_pestat] mean and std.dev: (623.95, 650.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4111)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 381)
[M::mem_pestat] mean and std.dev: (160.45, 65.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 471)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 458, 1046)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2812)
[M::mem_pestat] mean and std.dev: (592.29, 668.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3695)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 423, 1351)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3605)
[M::mem_pestat] mean and std.dev: (760.35, 820.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4732)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 767458 sequences (100000081 bp) in 3.972 CPU sec, 4.220 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 295019, 49, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (145, 277, 1577)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4441)
[M::mem_pestat] mean and std.dev: (710.40, 983.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5873)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 148, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 383)
[M::mem_pestat] mean and std.dev: (160.58, 66.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 474)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (137, 357, 1064)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2918)
[M::mem_pestat] mean and std.dev: (625.35, 693.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3845)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 267, 1195)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3223)
[M::mem_pestat] mean and std.dev: (559.62, 643.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4237)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 766504 sequences (100000169 bp) in 2.968 CPU sec, 2.980 real sec...
[M::mem_process_seqs] Processed 768434 reads in 287.128 CPU sec, 9.383 real sec
sorting block 51, #reads = 1083653 mem = 536879934 peak = 747048960
[M::mem_process_seqs] Processed 769990 reads in 191.738 CPU sec, 6.098 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 294495, 37, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 247, 540)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1236)
[M::mem_pestat] mean and std.dev: (305.54, 202.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1584)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 149, 204)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 390)
[M::mem_pestat] mean and std.dev: (162.64, 68.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 483)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 1141, 2119)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6035)
[M::mem_pestat] mean and std.dev: (1198.69, 1106.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7993)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 323, 908)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2348)
[M::mem_pestat] mean and std.dev: (483.48, 445.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3068)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 52, #reads = 1080879 mem = 536880649 peak = 747048960
[M::process] read 767388 sequences (100000023 bp) in 4.277 CPU sec, 4.569 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 294552, 51, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 218, 902)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2402)
[M::mem_pestat] mean and std.dev: (354.42, 387.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3152)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 150, 205)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 393)
[M::mem_pestat] mean and std.dev: (163.33, 69.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 487)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (328, 508, 867)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1945)
[M::mem_pestat] mean and std.dev: (489.26, 321.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2484)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 286, 1022)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2720)
[M::mem_pestat] mean and std.dev: (548.59, 588.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3569)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 767908 sequences (100000068 bp) in 2.564 CPU sec, 2.569 real sec...
[M::mem_process_seqs] Processed 767458 reads in 283.118 CPU sec, 9.252 real sec
[M::mem_process_seqs] Processed 766504 reads in 191.870 CPU sec, 6.095 real sec
sorting block 53, #reads = 1083496 mem = 536885904 peak = 747048960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 295104, 41, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 263, 954)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2530)
[M::mem_pestat] mean and std.dev: (488.54, 540.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3318)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 149, 204)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 390)
[M::mem_pestat] mean and std.dev: (162.32, 68.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 483)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (294, 1082, 3149)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8859)
[M::mem_pestat] mean and std.dev: (1997.39, 2208.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11714)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 272, 928)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2354)
[M::mem_pestat] mean and std.dev: (447.35, 431.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3067)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 766742 sequences (100000012 bp) in 4.218 CPU sec, 4.499 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 295438, 43, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 444, 664)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1530)
[M::mem_pestat] mean and std.dev: (435.18, 335.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1963)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 149, 204)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 390)
[M::mem_pestat] mean and std.dev: (162.36, 68.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 483)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (526, 780, 1222)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2614)
[M::mem_pestat] mean and std.dev: (772.12, 561.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3310)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 206, 676)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1718)
[M::mem_pestat] mean and std.dev: (389.84, 422.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2239)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 767388 reads in 277.641 CPU sec, 8.858 real sec
[M::process] read 767462 sequences (100000181 bp) in 3.060 CPU sec, 3.068 real sec...
[M::mem_process_seqs] Processed 767908 reads in 192.732 CPU sec, 6.124 real sec
sorting block 54, #reads = 1086506 mem = 536884476 peak = 747048960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 294541, 29, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 226, 626)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1530)
[M::mem_pestat] mean and std.dev: (322.23, 306.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1982)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 149, 205)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 393)
[M::mem_pestat] mean and std.dev: (163.03, 68.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 487)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (539, 962, 1547)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3563)
[M::mem_pestat] mean and std.dev: (1090.81, 807.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4571)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 542, 1044)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2698)
[M::mem_pestat] mean and std.dev: (633.81, 555.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3525)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 55, #reads = 1086924 mem = 536876652 peak = 747048960
[M::process] read 770978 sequences (100000068 bp) in 4.152 CPU sec, 4.407 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 294756, 29, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 382, 474)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 994)
[M::mem_pestat] mean and std.dev: (333.98, 181.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1254)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 149, 204)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 390)
[M::mem_pestat] mean and std.dev: (162.43, 68.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 483)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (88, 442, 1943)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5653)
[M::mem_pestat] mean and std.dev: (1029.41, 1340.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7508)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 408, 1043)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2677)
[M::mem_pestat] mean and std.dev: (629.63, 628.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3494)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 770838 sequences (100000029 bp) in 2.819 CPU sec, 2.820 real sec...
[M::mem_process_seqs] Processed 766742 reads in 282.581 CPU sec, 9.110 real sec
[M::mem_process_seqs] Processed 767462 reads in 187.558 CPU sec, 5.964 real sec
sorting block 56, #reads = 1084829 mem = 536884606 peak = 747048960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 296345, 34, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (251, 606, 1338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3512)
[M::mem_pestat] mean and std.dev: (712.05, 581.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4599)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 380)
[M::mem_pestat] mean and std.dev: (159.51, 66.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 470)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (276, 689, 1209)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3075)
[M::mem_pestat] mean and std.dev: (649.59, 475.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4008)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 373, 1022)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2696)
[M::mem_pestat] mean and std.dev: (452.07, 389.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3533)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 770842 sequences (100000131 bp) in 4.138 CPU sec, 4.367 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 295526, 36, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 276, 944)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2496)
[M::mem_pestat] mean and std.dev: (480.23, 432.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3272)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 377)
[M::mem_pestat] mean and std.dev: (159.39, 65.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 466)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 962, 2372)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6778)
[M::mem_pestat] mean and std.dev: (1286.20, 1391.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8981)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 307, 569)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1391)
[M::mem_pestat] mean and std.dev: (329.42, 254.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1802)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 770888 sequences (100000255 bp) in 3.098 CPU sec, 3.106 real sec...
[M::mem_process_seqs] Processed 770978 reads in 278.764 CPU sec, 8.884 real sec
sorting block 57, #reads = 1087243 mem = 536877782 peak = 747048960
[M::mem_process_seqs] Processed 770838 reads in 195.715 CPU sec, 6.213 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 295958, 35, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 574, 1178)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3182)
[M::mem_pestat] mean and std.dev: (621.45, 660.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4184)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 380)
[M::mem_pestat] mean and std.dev: (159.51, 65.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 470)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (94, 390, 1742)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5038)
[M::mem_pestat] mean and std.dev: (922.85, 1289.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6686)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 295, 941)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2479)
[M::mem_pestat] mean and std.dev: (431.37, 433.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3248)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 770500 sequences (100000257 bp) in 4.920 CPU sec, 5.168 real sec...
sorting block 58, #reads = 1084887 mem = 536882619 peak = 747048960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 295578, 31, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 329, 1094)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2936)
[M::mem_pestat] mean and std.dev: (586.85, 568.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3857)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 377)
[M::mem_pestat] mean and std.dev: (159.35, 65.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 466)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 318, 1047)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2823)
[M::mem_pestat] mean and std.dev: (618.87, 615.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3711)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 232, 570)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1328)
[M::mem_pestat] mean and std.dev: (291.76, 193.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1707)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 769162 sequences (100000169 bp) in 2.702 CPU sec, 2.706 real sec...
[M::mem_process_seqs] Processed 770842 reads in 278.222 CPU sec, 8.855 real sec
[M::mem_process_seqs] Processed 770888 reads in 194.823 CPU sec, 6.201 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 295408, 31, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 326, 832)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2134)
[M::mem_pestat] mean and std.dev: (522.28, 499.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2785)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 380)
[M::mem_pestat] mean and std.dev: (159.90, 66.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 470)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (145, 308, 737)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1921)
[M::mem_pestat] mean and std.dev: (469.43, 520.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2553)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 266, 869)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2295)
[M::mem_pestat] mean and std.dev: (426.33, 401.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3008)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 59, #reads = 1087374 mem = 536880084 peak = 747048960
[M::process] read 768376 sequences (100000002 bp) in 4.220 CPU sec, 4.423 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (77, 295197, 42, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (136, 203, 675)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1753)
[M::mem_pestat] mean and std.dev: (367.01, 396.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2292)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 384)
[M::mem_pestat] mean and std.dev: (160.90, 67.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 475)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (354, 862, 2040)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5412)
[M::mem_pestat] mean and std.dev: (927.97, 766.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7098)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 308, 1157)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3057)
[M::mem_pestat] mean and std.dev: (456.70, 399.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4007)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 770500 reads in 280.119 CPU sec, 8.944 real sec
[M::process] read 769654 sequences (100000088 bp) in 3.078 CPU sec, 3.098 real sec...
sorting block 60, #reads = 1084385 mem = 536880852 peak = 747048960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 294508, 35, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 225, 696)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1794)
[M::mem_pestat] mean and std.dev: (418.25, 430.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2343)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 203)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 387)
[M::mem_pestat] mean and std.dev: (161.51, 67.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 479)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (262, 575, 773)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1795)
[M::mem_pestat] mean and std.dev: (556.06, 384.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2306)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 276, 695)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1721)
[M::mem_pestat] mean and std.dev: (395.51, 328.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2234)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 769754 sequences (100000125 bp) in 3.352 CPU sec, 3.361 real sec...
[M::mem_process_seqs] Processed 768376 reads in 167.682 CPU sec, 5.824 real sec
[M::mem_process_seqs] Processed 769162 reads in 425.172 CPU sec, 14.048 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 294948, 24, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 260, 1188)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3260)
[M::mem_pestat] mean and std.dev: (613.40, 811.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4296)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 148, 200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 380)
[M::mem_pestat] mean and std.dev: (160.09, 66.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 470)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (233, 500, 2224)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6206)
[M::mem_pestat] mean and std.dev: (1029.54, 989.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8197)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 327, 1188)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3202)
[M::mem_pestat] mean and std.dev: (652.26, 637.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4209)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 61, #reads = 1083839 mem = 536879249 peak = 747048960
[M::process] read 768346 sequences (100000117 bp) in 5.107 CPU sec, 5.413 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 294500, 40, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 362, 786)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1990)
[M::mem_pestat] mean and std.dev: (507.22, 460.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2592)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 380)
[M::mem_pestat] mean and std.dev: (159.94, 66.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 470)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 691, 1840)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5124)
[M::mem_pestat] mean and std.dev: (1130.03, 1187.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6766)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 421, 926)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2410)
[M::mem_pestat] mean and std.dev: (555.93, 533.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3152)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 769654 reads in 321.371 CPU sec, 10.306 real sec
[M::mem_process_seqs] Processed 769754 reads in 202.507 CPU sec, 6.458 real sec
sorting block 62, #reads = 1084283 mem = 536882064 peak = 747048960
[M::process] read 769202 sequences (100000150 bp) in 3.039 CPU sec, 3.305 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 294719, 39, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (144, 219, 556)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1380)
[M::mem_pestat] mean and std.dev: (357.98, 322.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1792)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 384)
[M::mem_pestat] mean and std.dev: (161.20, 67.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 475)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 339, 1069)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2839)
[M::mem_pestat] mean and std.dev: (607.43, 605.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3724)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 259, 881)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2327)
[M::mem_pestat] mean and std.dev: (461.55, 461.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3050)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 768488 sequences (100000115 bp) in 3.416 CPU sec, 3.674 real sec...
sorting block 63, #reads = 1083843 mem = 536875493 peak = 747048960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 294132, 35, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 550, 960)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2530)
[M::mem_pestat] mean and std.dev: (595.54, 507.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3315)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 381)
[M::mem_pestat] mean and std.dev: (160.25, 66.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 471)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 408, 1392)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3798)
[M::mem_pestat] mean and std.dev: (660.38, 691.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5001)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 405, 1154)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3076)
[M::mem_pestat] mean and std.dev: (535.96, 600.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4037)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 768576 sequences (100000150 bp) in 2.917 CPU sec, 2.924 real sec...
[M::mem_process_seqs] Processed 768346 reads in 282.211 CPU sec, 8.991 real sec
[M::mem_process_seqs] Processed 769202 reads in 194.104 CPU sec, 6.167 real sec
sorting block 64, #reads = 1083537 mem = 536876920 peak = 747048960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 293837, 39, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 248, 481)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1145)
[M::mem_pestat] mean and std.dev: (296.83, 234.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1477)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 381)
[M::mem_pestat] mean and std.dev: (160.37, 66.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 471)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 591, 1476)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4108)
[M::mem_pestat] mean and std.dev: (769.34, 784.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5424)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 299, 937)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2465)
[M::mem_pestat] mean and std.dev: (492.64, 464.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3229)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 768544 sequences (100000169 bp) in 4.778 CPU sec, 5.024 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 294423, 37, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 305, 705)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1785)
[M::mem_pestat] mean and std.dev: (328.47, 261.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2325)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 381)
[M::mem_pestat] mean and std.dev: (160.49, 66.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 471)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 582, 1816)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5142)
[M::mem_pestat] mean and std.dev: (982.06, 1097.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6805)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 316, 745)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1871)
[M::mem_pestat] mean and std.dev: (451.37, 400.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2434)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 768032 sequences (100000153 bp) in 2.482 CPU sec, 2.489 real sec...
[M::mem_process_seqs] Processed 768488 reads in 274.676 CPU sec, 8.742 real sec
sorting block 65, #reads = 1082884 mem = 536880555 peak = 747048960
[M::mem_process_seqs] Processed 768576 reads in 206.913 CPU sec, 6.620 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 293218, 30, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 224, 1250)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3446)
[M::mem_pestat] mean and std.dev: (535.47, 713.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4544)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 381)
[M::mem_pestat] mean and std.dev: (160.53, 66.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 471)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (106, 349, 1187)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3349)
[M::mem_pestat] mean and std.dev: (583.36, 644.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4430)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 304, 505)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1193)
[M::mem_pestat] mean and std.dev: (320.12, 245.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1537)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 768042 sequences (100000225 bp) in 4.119 CPU sec, 4.344 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 293586, 54, 74)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 657, 1574)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4358)
[M::mem_pestat] mean and std.dev: (692.50, 585.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5750)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 381)
[M::mem_pestat] mean and std.dev: (160.65, 66.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 471)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 802, 1446)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3900)
[M::mem_pestat] mean and std.dev: (765.52, 746.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5127)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 290, 966)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2574)
[M::mem_pestat] mean and std.dev: (378.80, 411.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3378)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 768282 sequences (100000143 bp) in 2.620 CPU sec, 2.625 real sec...
[M::mem_process_seqs] Processed 768544 reads in 272.845 CPU sec, 8.702 real sec
sorting block 66, #reads = 1081750 mem = 536878124 peak = 747048960
[M::mem_process_seqs] Processed 768032 reads in 207.758 CPU sec, 6.645 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 293554, 35, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 530, 1679)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4667)
[M::mem_pestat] mean and std.dev: (967.34, 1145.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6161)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 381)
[M::mem_pestat] mean and std.dev: (160.43, 65.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 471)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (226, 507, 1246)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3286)
[M::mem_pestat] mean and std.dev: (608.59, 555.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4306)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 376, 1374)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3818)
[M::mem_pestat] mean and std.dev: (664.33, 755.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5040)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 67, #reads = 1079285 mem = 536880297 peak = 747048960
[M::process] read 768816 sequences (100000017 bp) in 4.121 CPU sec, 4.371 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 293677, 43, 74)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 286, 811)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2129)
[M::mem_pestat] mean and std.dev: (349.78, 321.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2788)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 381)
[M::mem_pestat] mean and std.dev: (160.48, 66.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 471)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 317, 1423)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3915)
[M::mem_pestat] mean and std.dev: (699.59, 852.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5161)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 375, 1201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3281)
[M::mem_pestat] mean and std.dev: (551.45, 563.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4321)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 768042 reads in 277.493 CPU sec, 8.870 real sec
[M::process] read 775828 sequences (100000027 bp) in 2.692 CPU sec, 2.696 real sec...
[M::mem_process_seqs] Processed 768282 reads in 196.783 CPU sec, 6.265 real sec
sorting block 68, #reads = 1080222 mem = 536881813 peak = 747048960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 293935, 43, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 260, 765)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1995)
[M::mem_pestat] mean and std.dev: (381.95, 342.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2610)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 378)
[M::mem_pestat] mean and std.dev: (159.76, 65.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 467)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (244, 464, 1699)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4609)
[M::mem_pestat] mean and std.dev: (966.17, 1081.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6064)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 404, 780)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1980)
[M::mem_pestat] mean and std.dev: (481.81, 426.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2580)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 772618 sequences (100000119 bp) in 4.731 CPU sec, 4.983 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 296377, 31, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (135, 224, 746)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1968)
[M::mem_pestat] mean and std.dev: (369.00, 384.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2579)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 144, 194)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 364)
[M::mem_pestat] mean and std.dev: (155.40, 62.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 449)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 319, 752)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1842)
[M::mem_pestat] mean and std.dev: (408.33, 355.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2387)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 270, 937)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2465)
[M::mem_pestat] mean and std.dev: (434.18, 448.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3229)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 773482 sequences (100000240 bp) in 3.076 CPU sec, 3.073 real sec...
[M::mem_process_seqs] Processed 768816 reads in 288.536 CPU sec, 9.172 real sec
sorting block 69, #reads = 1080177 mem = 536885005 peak = 747048960
[M::mem_process_seqs] Processed 775828 reads in 205.730 CPU sec, 6.544 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 295736, 30, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 225, 450)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1002)
[M::mem_pestat] mean and std.dev: (279.69, 195.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1278)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 146, 197)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 371)
[M::mem_pestat] mean and std.dev: (157.52, 63.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 458)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 684, 1133)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3017)
[M::mem_pestat] mean and std.dev: (591.81, 524.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3959)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 296, 1041)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2815)
[M::mem_pestat] mean and std.dev: (568.68, 565.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3702)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 70, #reads = 1078991 mem = 536877399 peak = 747048960
[M::process] read 774226 sequences (100000201 bp) in 4.867 CPU sec, 5.080 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 296158, 37, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 330, 944)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2456)
[M::mem_pestat] mean and std.dev: (568.51, 550.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3212)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 145, 196)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 370)
[M::mem_pestat] mean and std.dev: (157.07, 63.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 457)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 410, 1029)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2775)
[M::mem_pestat] mean and std.dev: (483.38, 527.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3648)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 335, 875)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2211)
[M::mem_pestat] mean and std.dev: (506.32, 481.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2879)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 773572 sequences (100000079 bp) in 2.607 CPU sec, 2.615 real sec...
[M::mem_process_seqs] Processed 772618 reads in 281.417 CPU sec, 8.971 real sec
[M::mem_process_seqs] Processed 773482 reads in 198.108 CPU sec, 6.308 real sec
sorting block 71, #reads = 1080955 mem = 536886167 peak = 747048960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 296163, 34, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 341, 482)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1026)
[M::mem_pestat] mean and std.dev: (339.13, 190.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1298)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 145, 195)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 367)
[M::mem_pestat] mean and std.dev: (156.54, 63.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 453)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 475, 868)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2260)
[M::mem_pestat] mean and std.dev: (515.06, 479.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2956)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 335, 978)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2588)
[M::mem_pestat] mean and std.dev: (502.82, 532.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3393)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 773278 sequences (100000292 bp) in 4.717 CPU sec, 4.908 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 296624, 46, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (142, 197, 699)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1813)
[M::mem_pestat] mean and std.dev: (366.67, 380.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2370)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 145, 196)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 370)
[M::mem_pestat] mean and std.dev: (156.82, 63.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 457)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (146, 317, 775)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2033)
[M::mem_pestat] mean and std.dev: (436.76, 453.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2662)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 435, 1514)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4150)
[M::mem_pestat] mean and std.dev: (794.02, 817.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5468)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 774226 reads in 284.461 CPU sec, 9.078 real sec
[M::process] read 769996 sequences (100000228 bp) in 3.187 CPU sec, 3.220 real sec...
sorting block 72, #reads = 1082439 mem = 536882312 peak = 747048960
[M::mem_process_seqs] Processed 773572 reads in 198.844 CPU sec, 6.333 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 296677, 35, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 321, 844)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2144)
[M::mem_pestat] mean and std.dev: (488.10, 447.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2794)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 146, 197)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 371)
[M::mem_pestat] mean and std.dev: (157.32, 63.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 458)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (294, 840, 2815)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7857)
[M::mem_pestat] mean and std.dev: (1826.31, 2086.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10378)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 432, 915)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2357)
[M::mem_pestat] mean and std.dev: (509.74, 429.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3078)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 774296 sequences (100000210 bp) in 3.936 CPU sec, 4.146 real sec...
sorting block 73, #reads = 1083712 mem = 536884463 peak = 747048960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 295793, 45, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 478, 1829)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5157)
[M::mem_pestat] mean and std.dev: (826.00, 1044.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6821)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 377)
[M::mem_pestat] mean and std.dev: (159.38, 65.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 466)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (239, 418, 827)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2003)
[M::mem_pestat] mean and std.dev: (510.56, 401.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2591)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 252, 581)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1399)
[M::mem_pestat] mean and std.dev: (335.49, 280.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1808)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 774360 sequences (100000133 bp) in 2.755 CPU sec, 2.766 real sec...
[M::mem_process_seqs] Processed 773278 reads in 286.889 CPU sec, 9.227 real sec
[M::mem_process_seqs] Processed 769996 reads in 203.464 CPU sec, 6.535 real sec
sorting block 74, #reads = 1083798 mem = 536884016 peak = 747048960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 296702, 37, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (130, 175, 632)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1636)
[M::mem_pestat] mean and std.dev: (318.38, 334.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2138)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 145, 195)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 367)
[M::mem_pestat] mean and std.dev: (156.42, 63.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 453)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 1059, 1727)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4793)
[M::mem_pestat] mean and std.dev: (931.09, 823.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6326)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (234, 460, 957)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2403)
[M::mem_pestat] mean and std.dev: (550.27, 433.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3126)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 773352 sequences (100000121 bp) in 4.423 CPU sec, 4.632 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 296814, 32, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (143, 219, 682)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1760)
[M::mem_pestat] mean and std.dev: (401.40, 377.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2299)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 145, 195)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 367)
[M::mem_pestat] mean and std.dev: (156.50, 63.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 453)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (263, 526, 1868)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5078)
[M::mem_pestat] mean and std.dev: (742.25, 656.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6683)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 240, 452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1044)
[M::mem_pestat] mean and std.dev: (271.93, 183.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1340)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 774296 reads in 281.834 CPU sec, 8.996 real sec
[M::process] read 771462 sequences (100000247 bp) in 3.165 CPU sec, 3.200 real sec...
[M::mem_process_seqs] Processed 774360 reads in 197.668 CPU sec, 6.261 real sec
sorting block 75, #reads = 1084240 mem = 536882536 peak = 747048960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 296559, 27, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 314, 1183)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3159)
[M::mem_pestat] mean and std.dev: (612.92, 578.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4147)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 145, 196)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 370)
[M::mem_pestat] mean and std.dev: (157.13, 63.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 457)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (244, 636, 1121)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2875)
[M::mem_pestat] mean and std.dev: (538.04, 420.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3752)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 325, 827)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2131)
[M::mem_pestat] mean and std.dev: (515.83, 485.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2783)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 76, #reads = 1082723 mem = 536877203 peak = 747048960
[M::process] read 770000 sequences (100000054 bp) in 4.203 CPU sec, 4.420 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (74, 295456, 37, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 372, 1095)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2937)
[M::mem_pestat] mean and std.dev: (587.53, 538.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3858)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 374)
[M::mem_pestat] mean and std.dev: (158.50, 64.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 462)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (376, 891, 2193)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5827)
[M::mem_pestat] mean and std.dev: (1171.22, 1087.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7644)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 309, 895)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2321)
[M::mem_pestat] mean and std.dev: (506.65, 495.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3034)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 771742 sequences (100000222 bp) in 2.144 CPU sec, 2.151 real sec...
[M::mem_process_seqs] Processed 773352 reads in 256.949 CPU sec, 8.194 real sec
[M::mem_process_seqs] Processed 771462 reads in 166.127 CPU sec, 5.279 real sec
sorting block 77, #reads = 1084077 mem = 536880158 peak = 747048960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 294604, 43, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 424, 1455)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4007)
[M::mem_pestat] mean and std.dev: (719.93, 688.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5283)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 380)
[M::mem_pestat] mean and std.dev: (159.50, 65.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 470)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (244, 772, 1328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3496)
[M::mem_pestat] mean and std.dev: (712.42, 572.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4580)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (240, 354, 888)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2184)
[M::mem_pestat] mean and std.dev: (532.68, 472.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2832)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 769062 sequences (100000008 bp) in 3.746 CPU sec, 3.950 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 295216, 43, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 370, 1268)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3458)
[M::mem_pestat] mean and std.dev: (559.62, 591.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4553)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 146, 197)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 371)
[M::mem_pestat] mean and std.dev: (157.92, 64.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 458)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (249, 431, 1273)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3321)
[M::mem_pestat] mean and std.dev: (695.74, 797.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4345)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 340, 899)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2355)
[M::mem_pestat] mean and std.dev: (507.78, 452.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3083)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 770000 reads in 242.059 CPU sec, 7.808 real sec
[M::process] read 768570 sequences (100000204 bp) in 3.127 CPU sec, 3.143 real sec...
[M::mem_process_seqs] Processed 771742 reads in 166.138 CPU sec, 5.259 real sec
sorting block 78, #reads = 1080075 mem = 536882665 peak = 747048960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 293452, 34, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 227, 467)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1089)
[M::mem_pestat] mean and std.dev: (266.16, 187.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1400)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 378)
[M::mem_pestat] mean and std.dev: (159.83, 65.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 467)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 521, 1966)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5574)
[M::mem_pestat] mean and std.dev: (812.73, 1038.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7378)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 347, 764)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1898)
[M::mem_pestat] mean and std.dev: (471.69, 357.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2465)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 769242 sequences (100000074 bp) in 3.771 CPU sec, 3.981 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 292275, 42, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 321, 764)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1962)
[M::mem_pestat] mean and std.dev: (485.47, 479.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2561)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 381)
[M::mem_pestat] mean and std.dev: (160.30, 65.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 471)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (274, 514, 1303)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3361)
[M::mem_pestat] mean and std.dev: (659.00, 619.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4390)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 300, 708)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1782)
[M::mem_pestat] mean and std.dev: (422.16, 358.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2319)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 767280 sequences (100000000 bp) in 2.055 CPU sec, 2.059 real sec...
[M::mem_process_seqs] Processed 769062 reads in 243.313 CPU sec, 7.771 real sec
sorting block 79, #reads = 1082194 mem = 536880818 peak = 747048960
[M::mem_process_seqs] Processed 768570 reads in 185.903 CPU sec, 5.968 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 292999, 39, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (143, 310, 966)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2612)
[M::mem_pestat] mean and std.dev: (491.35, 544.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3435)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 378)
[M::mem_pestat] mean and std.dev: (159.61, 65.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 467)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 364, 1651)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4599)
[M::mem_pestat] mean and std.dev: (652.60, 656.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6073)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 320, 1054)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2810)
[M::mem_pestat] mean and std.dev: (611.05, 568.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3688)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 80, #reads = 1078358 mem = 536876196 peak = 747048960
[M::process] read 769148 sequences (100000257 bp) in 3.661 CPU sec, 3.835 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 292919, 28, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 276, 807)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2115)
[M::mem_pestat] mean and std.dev: (394.67, 374.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2769)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 384)
[M::mem_pestat] mean and std.dev: (160.94, 66.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 475)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (331, 600, 1437)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3649)
[M::mem_pestat] mean and std.dev: (794.56, 652.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4755)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 230, 423)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 949)
[M::mem_pestat] mean and std.dev: (253.47, 157.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1212)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 769242 reads in 224.035 CPU sec, 7.126 real sec
[M::process] read 768996 sequences (100000108 bp) in 2.425 CPU sec, 2.430 real sec...
[M::mem_process_seqs] Processed 767280 reads in 152.924 CPU sec, 4.852 real sec
sorting block 81, #reads = 1076707 mem = 536891892 peak = 747048960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 292880, 33, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 231, 547)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1313)
[M::mem_pestat] mean and std.dev: (262.77, 150.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1696)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 378)
[M::mem_pestat] mean and std.dev: (159.73, 65.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 467)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (447, 598, 1272)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2922)
[M::mem_pestat] mean and std.dev: (626.41, 483.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3747)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 279, 649)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1615)
[M::mem_pestat] mean and std.dev: (383.61, 311.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2098)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 767814 sequences (100000186 bp) in 4.106 CPU sec, 4.292 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 293267, 39, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 354, 1080)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2860)
[M::mem_pestat] mean and std.dev: (616.94, 653.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3750)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 378)
[M::mem_pestat] mean and std.dev: (159.96, 65.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 467)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 651, 2207)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6277)
[M::mem_pestat] mean and std.dev: (1199.71, 1524.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8312)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 330, 843)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2193)
[M::mem_pestat] mean and std.dev: (452.70, 461.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2868)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 769148 reads in 219.817 CPU sec, 6.999 real sec
sorting block 82, #reads = 1077120 mem = 536879665 peak = 747048960
[M::process] read 769072 sequences (100000017 bp) in 2.503 CPU sec, 2.607 real sec...
[M::mem_process_seqs] Processed 768996 reads in 149.722 CPU sec, 4.745 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 293167, 29, 75)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 264, 550)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1290)
[M::mem_pestat] mean and std.dev: (342.34, 265.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1660)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 381)
[M::mem_pestat] mean and std.dev: (160.31, 65.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 471)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 542, 1245)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3353)
[M::mem_pestat] mean and std.dev: (642.23, 711.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4407)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (240, 374, 1162)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3006)
[M::mem_pestat] mean and std.dev: (650.97, 645.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3928)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 83, #reads = 1077006 mem = 536880322 peak = 747048960
[M::process] read 769306 sequences (100000056 bp) in 3.697 CPU sec, 3.913 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 293743, 39, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (138, 234, 1156)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3192)
[M::mem_pestat] mean and std.dev: (574.68, 669.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4210)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 375)
[M::mem_pestat] mean and std.dev: (159.26, 64.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 463)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 517, 1665)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4697)
[M::mem_pestat] mean and std.dev: (703.76, 863.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6213)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 311, 634)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1566)
[M::mem_pestat] mean and std.dev: (328.00, 233.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2032)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 767814 reads in 211.043 CPU sec, 6.730 real sec
[M::mem_process_seqs] Processed 769072 reads in 146.637 CPU sec, 4.630 real sec
[M::process] read 773030 sequences (100000078 bp) in 3.050 CPU sec, 3.180 real sec...
sorting block 84, #reads = 1076640 mem = 536879149 peak = 747048960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 293423, 30, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 289, 840)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2136)
[M::mem_pestat] mean and std.dev: (472.13, 397.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2784)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 147, 200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 378)
[M::mem_pestat] mean and std.dev: (159.50, 65.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 467)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (803, 1497, 2304)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5306)
[M::mem_pestat] mean and std.dev: (1570.89, 1132.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6807)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 401, 1536)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4158)
[M::mem_pestat] mean and std.dev: (824.08, 781.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5469)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 779616 sequences (100000282 bp) in 3.712 CPU sec, 3.985 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 295010, 31, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 363, 819)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2081)
[M::mem_pestat] mean and std.dev: (470.23, 398.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2712)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 146, 197)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 371)
[M::mem_pestat] mean and std.dev: (157.34, 63.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 458)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 544, 1636)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4482)
[M::mem_pestat] mean and std.dev: (570.85, 550.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5905)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 280, 901)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2341)
[M::mem_pestat] mean and std.dev: (451.71, 384.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3061)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 777384 sequences (100000065 bp) in 2.080 CPU sec, 2.077 real sec...
[M::mem_process_seqs] Processed 769306 reads in 216.632 CPU sec, 6.894 real sec
sorting block 85, #reads = 1076693 mem = 536879918 peak = 747048960
[M::mem_process_seqs] Processed 773030 reads in 150.655 CPU sec, 4.787 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 297376, 46, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (141, 294, 692)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1794)
[M::mem_pestat] mean and std.dev: (391.66, 302.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2345)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (108, 142, 191)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 357)
[M::mem_pestat] mean and std.dev: (153.56, 61.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 440)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (327, 739, 1026)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2424)
[M::mem_pestat] mean and std.dev: (672.02, 512.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3123)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 309, 861)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2265)
[M::mem_pestat] mean and std.dev: (372.60, 320.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2967)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 86, #reads = 1074832 mem = 536881464 peak = 747048960
[M::process] read 776370 sequences (100000169 bp) in 4.378 CPU sec, 4.566 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 296844, 30, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (146, 269, 893)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2387)
[M::mem_pestat] mean and std.dev: (453.89, 471.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3134)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (108, 144, 194)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 366)
[M::mem_pestat] mean and std.dev: (155.20, 62.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 452)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (101, 485, 785)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2153)
[M::mem_pestat] mean and std.dev: (449.58, 407.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2837)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 293, 1241)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3371)
[M::mem_pestat] mean and std.dev: (641.34, 683.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4436)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 775114 sequences (100000010 bp) in 2.258 CPU sec, 2.260 real sec...
[M::mem_process_seqs] Processed 779616 reads in 234.245 CPU sec, 7.434 real sec
[M::mem_process_seqs] Processed 777384 reads in 160.042 CPU sec, 5.081 real sec
sorting block 87, #reads = 1069161 mem = 536876700 peak = 747048960
[M::process] read 774994 sequences (100000281 bp) in 3.786 CPU sec, 4.010 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 296887, 36, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 262, 1082)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2910)
[M::mem_pestat] mean and std.dev: (613.69, 724.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3824)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 145, 195)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 367)
[M::mem_pestat] mean and std.dev: (156.39, 63.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 453)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 498, 1421)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3837)
[M::mem_pestat] mean and std.dev: (796.27, 933.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5045)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 304, 570)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1368)
[M::mem_pestat] mean and std.dev: (332.88, 218.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1767)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 772986 sequences (100000077 bp) in 2.050 CPU sec, 2.051 real sec...
[M::mem_process_seqs] Processed 775114 reads in 118.135 CPU sec, 3.725 real sec
sorting block 88, #reads = 1073032 mem = 536882975 peak = 747048960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 296727, 41, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 336, 567)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1389)
[M::mem_pestat] mean and std.dev: (363.25, 256.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1800)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 144, 194)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 364)
[M::mem_pestat] mean and std.dev: (155.65, 62.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 449)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 433, 1385)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3843)
[M::mem_pestat] mean and std.dev: (705.92, 763.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5072)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 312, 773)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1941)
[M::mem_pestat] mean and std.dev: (385.93, 305.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2525)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 296479, 40, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (143, 207, 643)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1643)
[M::mem_pestat] mean and std.dev: (293.02, 265.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2143)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 145, 196)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 370)
[M::mem_pestat] mean and std.dev: (156.74, 63.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 457)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 432, 939)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2457)
[M::mem_pestat] mean and std.dev: (577.54, 577.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3216)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (283, 427, 898)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2128)
[M::mem_pestat] mean and std.dev: (518.74, 397.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2743)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 776370 reads in 336.409 CPU sec, 10.657 real sec
[M::process] read 773982 sequences (100000237 bp) in 3.049 CPU sec, 3.053 real sec...
[M::mem_process_seqs] Processed 774994 reads in 182.007 CPU sec, 5.790 real sec
sorting block 89, #reads = 1076152 mem = 536883294 peak = 747048960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 296385, 38, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 485, 1465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4013)
[M::mem_pestat] mean and std.dev: (807.00, 906.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5287)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 146, 198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 376)
[M::mem_pestat] mean and std.dev: (158.30, 65.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 465)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 496, 979)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2631)
[M::mem_pestat] mean and std.dev: (519.88, 544.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3457)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 312, 795)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2051)
[M::mem_pestat] mean and std.dev: (453.44, 409.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2679)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 774132 sequences (100000273 bp) in 3.549 CPU sec, 3.795 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 296918, 42, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 343, 970)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2502)
[M::mem_pestat] mean and std.dev: (555.45, 498.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3268)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 145, 197)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 373)
[M::mem_pestat] mean and std.dev: (157.50, 64.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 461)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 326, 1389)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3855)
[M::mem_pestat] mean and std.dev: (785.14, 1081.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5109)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 278, 653)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1593)
[M::mem_pestat] mean and std.dev: (398.85, 355.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2063)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 773980 sequences (100000165 bp) in 2.178 CPU sec, 2.187 real sec...
[M::mem_process_seqs] Processed 772986 reads in 208.347 CPU sec, 6.625 real sec
sorting block 90, #reads = 1075073 mem = 536880466 peak = 747048960
[M::mem_process_seqs] Processed 773982 reads in 142.669 CPU sec, 4.532 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 296877, 43, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 492, 1280)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3490)
[M::mem_pestat] mean and std.dev: (627.60, 679.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4595)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 145, 196)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 370)
[M::mem_pestat] mean and std.dev: (156.81, 63.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 457)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 300, 999)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2685)
[M::mem_pestat] mean and std.dev: (587.44, 676.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3528)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 300, 574)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1314)
[M::mem_pestat] mean and std.dev: (392.82, 285.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1684)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 91, #reads = 1079606 mem = 536883282 peak = 747048960
[M::process] read 772658 sequences (100000013 bp) in 3.142 CPU sec, 3.453 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 296510, 34, 80)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (146, 214, 750)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1958)
[M::mem_pestat] mean and std.dev: (383.48, 380.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2562)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 145, 196)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 370)
[M::mem_pestat] mean and std.dev: (156.84, 63.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 457)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (425, 821, 1570)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3860)
[M::mem_pestat] mean and std.dev: (983.28, 889.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5005)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (233, 429, 1027)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2615)
[M::mem_pestat] mean and std.dev: (550.33, 444.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3409)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 769882 sequences (100000169 bp) in 2.120 CPU sec, 2.114 real sec...
[M::mem_process_seqs] Processed 774132 reads in 210.945 CPU sec, 6.722 real sec
[M::mem_process_seqs] Processed 773980 reads in 144.215 CPU sec, 4.579 real sec
sorting block 92, #reads = 1080070 mem = 536883233 peak = 747048960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 296082, 25, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (133, 239, 1167)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3235)
[M::mem_pestat] mean and std.dev: (507.65, 579.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4269)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 146, 197)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 371)
[M::mem_pestat] mean and std.dev: (157.74, 64.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 458)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 1130, 2400)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6844)
[M::mem_pestat] mean and std.dev: (1603.54, 1695.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9066)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 495, 1223)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3243)
[M::mem_pestat] mean and std.dev: (751.97, 675.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4253)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 771938 sequences (100000238 bp) in 3.790 CPU sec, 4.034 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 295220, 36, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 362, 1330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3610)
[M::mem_pestat] mean and std.dev: (611.74, 650.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4750)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 148, 200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 380)
[M::mem_pestat] mean and std.dev: (159.73, 65.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 470)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 558, 3241)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9329)
[M::mem_pestat] mean and std.dev: (1652.17, 2421.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12373)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 342, 1154)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3148)
[M::mem_pestat] mean and std.dev: (737.22, 844.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4145)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 770814 sequences (100000109 bp) in 2.150 CPU sec, 2.148 real sec...
[M::mem_process_seqs] Processed 772658 reads in 214.116 CPU sec, 6.805 real sec
sorting block 93, #reads = 1079238 mem = 536878653 peak = 747048960
[M::mem_process_seqs] Processed 769882 reads in 143.342 CPU sec, 4.553 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (73, 295470, 42, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (146, 315, 943)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2537)
[M::mem_pestat] mean and std.dev: (499.51, 525.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3334)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 146, 197)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 371)
[M::mem_pestat] mean and std.dev: (157.84, 64.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 458)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (321, 924, 2113)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5697)
[M::mem_pestat] mean and std.dev: (1125.45, 1013.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7489)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 353, 869)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2251)
[M::mem_pestat] mean and std.dev: (532.89, 518.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2942)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 94, #reads = 1079980 mem = 536877119 peak = 747048960
[M::process] read 770052 sequences (100000132 bp) in 3.303 CPU sec, 3.594 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 294446, 29, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 248, 827)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2133)
[M::mem_pestat] mean and std.dev: (427.85, 481.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2786)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 374)
[M::mem_pestat] mean and std.dev: (158.55, 64.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 462)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (479, 614, 3547)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9683)
[M::mem_pestat] mean and std.dev: (2240.79, 2739.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13200)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 245, 750)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1888)
[M::mem_pestat] mean and std.dev: (463.73, 430.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2457)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 770188 sequences (100000062 bp) in 2.090 CPU sec, 2.093 real sec...
[M::mem_process_seqs] Processed 771938 reads in 211.519 CPU sec, 6.738 real sec
[M::mem_process_seqs] Processed 770814 reads in 143.979 CPU sec, 4.570 real sec
sorting block 95, #reads = 1077322 mem = 536882280 peak = 747048960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 293813, 43, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 469, 1036)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2752)
[M::mem_pestat] mean and std.dev: (554.66, 493.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3610)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 377)
[M::mem_pestat] mean and std.dev: (159.21, 65.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 466)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (554, 933, 1695)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3977)
[M::mem_pestat] mean and std.dev: (1184.19, 858.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5118)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 383, 821)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2101)
[M::mem_pestat] mean and std.dev: (468.87, 439.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2741)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 767462 sequences (100000282 bp) in 3.367 CPU sec, 3.592 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 293772, 43, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 347, 1018)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2676)
[M::mem_pestat] mean and std.dev: (524.81, 514.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3505)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 377)
[M::mem_pestat] mean and std.dev: (159.24, 65.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 466)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (361, 572, 1357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3349)
[M::mem_pestat] mean and std.dev: (709.83, 540.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4345)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 315, 859)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2265)
[M::mem_pestat] mean and std.dev: (449.24, 455.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2968)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 769828 sequences (100000186 bp) in 2.195 CPU sec, 2.201 real sec...
[M::mem_process_seqs] Processed 770052 reads in 212.339 CPU sec, 6.755 real sec
sorting block 96, #reads = 1075846 mem = 536879778 peak = 747048960
[M::mem_process_seqs] Processed 770188 reads in 143.640 CPU sec, 4.562 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (79, 292427, 37, 80)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 324, 1080)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2862)
[M::mem_pestat] mean and std.dev: (561.11, 557.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3753)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 149, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 381)
[M::mem_pestat] mean and std.dev: (160.81, 66.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 471)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (476, 750, 1253)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2807)
[M::mem_pestat] mean and std.dev: (683.91, 455.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3584)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 345, 1134)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3044)
[M::mem_pestat] mean and std.dev: (625.34, 689.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3999)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 97, #reads = 1076228 mem = 536879846 peak = 747048960
[M::process] read 769862 sequences (100000075 bp) in 3.430 CPU sec, 3.670 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 293343, 41, 73)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 389, 1126)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3052)
[M::mem_pestat] mean and std.dev: (578.21, 507.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4015)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 377)
[M::mem_pestat] mean and std.dev: (159.12, 64.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 466)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 487, 1071)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2855)
[M::mem_pestat] mean and std.dev: (597.72, 562.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3747)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 462, 1409)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3863)
[M::mem_pestat] mean and std.dev: (759.20, 814.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5090)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 767462 reads in 210.319 CPU sec, 6.697 real sec
[M::process] read 769634 sequences (100000196 bp) in 2.150 CPU sec, 2.147 real sec...
[M::mem_process_seqs] Processed 769828 reads in 143.145 CPU sec, 4.540 real sec
sorting block 98, #reads = 1077480 mem = 536878610 peak = 747048960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 293582, 31, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 312, 958)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2534)
[M::mem_pestat] mean and std.dev: (536.52, 607.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3322)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 377)
[M::mem_pestat] mean and std.dev: (159.30, 65.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 466)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 342, 1089)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2929)
[M::mem_pestat] mean and std.dev: (501.92, 585.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3849)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 586, 1281)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3391)
[M::mem_pestat] mean and std.dev: (730.27, 671.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4446)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 770056 sequences (100000244 bp) in 3.356 CPU sec, 3.603 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 293228, 35, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 270, 689)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1721)
[M::mem_pestat] mean and std.dev: (357.56, 317.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2237)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 147, 199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 375)
[M::mem_pestat] mean and std.dev: (159.04, 64.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 463)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 250, 1093)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2977)
[M::mem_pestat] mean and std.dev: (501.34, 554.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3919)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 326, 820)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2162)
[M::mem_pestat] mean and std.dev: (449.31, 424.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2833)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 769844 sequences (100000062 bp) in 2.170 CPU sec, 2.163 real sec...
[M::mem_process_seqs] Processed 769862 reads in 209.107 CPU sec, 6.659 real sec
sorting block 99, #reads = 1077458 mem = 536879963 peak = 747048960
[M::mem_process_seqs] Processed 769634 reads in 142.721 CPU sec, 4.527 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 293472, 35, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 257, 673)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1669)
[M::mem_pestat] mean and std.dev: (361.00, 290.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2167)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 374)
[M::mem_pestat] mean and std.dev: (158.67, 64.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 462)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (269, 816, 2180)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6002)
[M::mem_pestat] mean and std.dev: (1349.55, 1452.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7913)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 325, 808)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2116)
[M::mem_pestat] mean and std.dev: (376.77, 305.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2770)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 100, #reads = 1075614 mem = 536886160 peak = 747048960
[M::process] read 774502 sequences (100000220 bp) in 3.931 CPU sec, 4.192 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 293343, 38, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (251, 532, 1560)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4178)
[M::mem_pestat] mean and std.dev: (906.20, 972.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5487)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 377)
[M::mem_pestat] mean and std.dev: (158.97, 64.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 466)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (105, 392, 1142)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3216)
[M::mem_pestat] mean and std.dev: (526.18, 683.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4253)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 304, 1278)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3446)
[M::mem_pestat] mean and std.dev: (649.23, 670.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4530)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 773890 sequences (100000077 bp) in 2.070 CPU sec, 2.072 real sec...
[M::mem_process_seqs] Processed 770056 reads in 215.006 CPU sec, 6.832 real sec
[M::mem_process_seqs] Processed 769844 reads in 151.121 CPU sec, 4.802 real sec
sorting block 101, #reads = 1074265 mem = 536878136 peak = 747048960
[M::process] read 773478 sequences (100000295 bp) in 4.225 CPU sec, 4.469 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 296597, 33, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (141, 336, 672)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1734)
[M::mem_pestat] mean and std.dev: (419.67, 395.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2265)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 145, 196)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 370)
[M::mem_pestat] mean and std.dev: (157.07, 63.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 457)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 408, 559)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1313)
[M::mem_pestat] mean and std.dev: (296.07, 189.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1690)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 314, 931)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2407)
[M::mem_pestat] mean and std.dev: (473.08, 430.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3145)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 773034 sequences (100000213 bp) in 2.133 CPU sec, 2.141 real sec...
[M::mem_process_seqs] Processed 773890 reads in 125.056 CPU sec, 3.975 real sec
sorting block 102, #reads = 1075229 mem = 536882301 peak = 747048960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (74, 294961, 44, 77)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (143, 249, 815)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2159)
[M::mem_pestat] mean and std.dev: (375.58, 380.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2831)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 145, 195)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 367)
[M::mem_pestat] mean and std.dev: (156.24, 63.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 453)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (399, 1041, 1877)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4833)
[M::mem_pestat] mean and std.dev: (981.51, 817.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6311)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 284, 1012)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2720)
[M::mem_pestat] mean and std.dev: (475.86, 567.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3574)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 296860, 25, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 412, 738)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1774)
[M::mem_pestat] mean and std.dev: (432.75, 327.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2292)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 145, 197)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 373)
[M::mem_pestat] mean and std.dev: (157.44, 64.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 461)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 421, 1337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3655)
[M::mem_pestat] mean and std.dev: (646.33, 698.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4814)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 226, 674)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1718)
[M::mem_pestat] mean and std.dev: (379.74, 416.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2240)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 772638 sequences (100000239 bp) in 2.277 CPU sec, 2.285 real sec...
[M::mem_process_seqs] Processed 774502 reads in 345.683 CPU sec, 10.996 real sec
[M::mem_process_seqs] Processed 773478 reads in 171.268 CPU sec, 5.472 real sec
sorting block 103, #reads = 1069190 mem = 536881071 peak = 747048960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 296017, 44, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 415, 1090)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2960)
[M::mem_pestat] mean and std.dev: (655.65, 642.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3895)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 146, 198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 376)
[M::mem_pestat] mean and std.dev: (158.01, 64.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 465)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (375, 920, 2502)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6756)
[M::mem_pestat] mean and std.dev: (1666.64, 1860.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9110)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 299, 797)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1971)
[M::mem_pestat] mean and std.dev: (450.67, 394.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2558)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 769494 sequences (100000072 bp) in 4.105 CPU sec, 4.352 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 296255, 24, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 219, 802)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2112)
[M::mem_pestat] mean and std.dev: (434.72, 449.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2767)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 146, 197)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 371)
[M::mem_pestat] mean and std.dev: (157.65, 64.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 458)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (271, 679, 1550)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4108)
[M::mem_pestat] mean and std.dev: (865.41, 1011.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5387)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 358, 741)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1839)
[M::mem_pestat] mean and std.dev: (375.09, 287.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2388)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 773034 reads in 205.374 CPU sec, 6.539 real sec
[M::mem_process_seqs] Processed 772638 reads in 139.508 CPU sec, 4.422 real sec
sorting block 104, #reads = 1085395 mem = 536885107 peak = 747048960
[M::process] read 771984 sequences (100000168 bp) in 3.019 CPU sec, 3.199 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 294944, 46, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 299, 722)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1858)
[M::mem_pestat] mean and std.dev: (396.56, 385.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2426)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 381)
[M::mem_pestat] mean and std.dev: (160.61, 66.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 471)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (333, 894, 1605)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4149)
[M::mem_pestat] mean and std.dev: (927.40, 697.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5421)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 390, 1044)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2740)
[M::mem_pestat] mean and std.dev: (528.06, 495.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3588)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 105, #reads = 1084993 mem = 536883425 peak = 747048960
[M::process] read 772552 sequences (100000129 bp) in 3.554 CPU sec, 3.843 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 296238, 33, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (136, 233, 417)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 979)
[M::mem_pestat] mean and std.dev: (243.45, 159.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1260)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 374)
[M::mem_pestat] mean and std.dev: (158.47, 64.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 462)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 664, 1941)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5515)
[M::mem_pestat] mean and std.dev: (1077.97, 1128.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7302)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 254, 450)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1034)
[M::mem_pestat] mean and std.dev: (305.55, 227.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1326)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 769494 reads in 206.988 CPU sec, 6.593 real sec
[M::mem_process_seqs] Processed 771984 reads in 138.985 CPU sec, 4.392 real sec
[M::process] read 772960 sequences (100000016 bp) in 2.379 CPU sec, 2.490 real sec...
sorting block 106, #reads = 1083969 mem = 536880439 peak = 747048960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 296769, 39, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 342, 613)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1521)
[M::mem_pestat] mean and std.dev: (377.61, 319.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1975)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 146, 198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 374)
[M::mem_pestat] mean and std.dev: (158.20, 64.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 462)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 731, 1506)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4194)
[M::mem_pestat] mean and std.dev: (798.03, 684.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5538)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 261, 393)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 887)
[M::mem_pestat] mean and std.dev: (282.50, 185.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1134)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 772656 sequences (100000040 bp) in 3.589 CPU sec, 3.830 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 296485, 38, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 242, 548)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1336)
[M::mem_pestat] mean and std.dev: (311.00, 228.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1730)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 146, 197)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 371)
[M::mem_pestat] mean and std.dev: (157.58, 63.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 458)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (129, 321, 1202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3348)
[M::mem_pestat] mean and std.dev: (582.42, 771.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4421)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (142, 271, 732)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1912)
[M::mem_pestat] mean and std.dev: (462.34, 481.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2502)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 772552 reads in 202.882 CPU sec, 6.460 real sec
[M::process] read 771810 sequences (100000093 bp) in 2.188 CPU sec, 2.214 real sec...
[M::mem_process_seqs] Processed 772960 reads in 139.683 CPU sec, 4.422 real sec
sorting block 107, #reads = 1084924 mem = 536882332 peak = 747048960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 296060, 34, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 220, 461)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1087)
[M::mem_pestat] mean and std.dev: (286.33, 203.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1400)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 146, 198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 374)
[M::mem_pestat] mean and std.dev: (158.11, 64.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 462)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (55, 408, 684)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1942)
[M::mem_pestat] mean and std.dev: (387.28, 370.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2571)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (275, 525, 1394)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3632)
[M::mem_pestat] mean and std.dev: (787.67, 736.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4751)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 772370 sequences (100000113 bp) in 3.731 CPU sec, 4.004 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 295735, 35, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (141, 245, 594)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1500)
[M::mem_pestat] mean and std.dev: (314.09, 321.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1953)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 374)
[M::mem_pestat] mean and std.dev: (158.47, 64.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 462)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 479, 1069)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2813)
[M::mem_pestat] mean and std.dev: (522.28, 481.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3685)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 489, 1549)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4349)
[M::mem_pestat] mean and std.dev: (715.43, 742.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5749)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 772656 reads in 201.952 CPU sec, 6.425 real sec
[M::process] read 770268 sequences (100000114 bp) in 1.848 CPU sec, 1.850 real sec...
sorting block 108, #reads = 1082537 mem = 536882457 peak = 747048960
[M::mem_process_seqs] Processed 771810 reads in 136.364 CPU sec, 4.334 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 295871, 41, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 344, 802)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2034)
[M::mem_pestat] mean and std.dev: (467.78, 405.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2650)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 146, 198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 374)
[M::mem_pestat] mean and std.dev: (158.25, 64.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 462)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (376, 936, 3051)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8401)
[M::mem_pestat] mean and std.dev: (1808.30, 2084.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11076)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 363, 626)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1506)
[M::mem_pestat] mean and std.dev: (375.65, 237.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1946)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 109, #reads = 1084029 mem = 536884486 peak = 747048960
[M::process] read 771784 sequences (100000153 bp) in 3.413 CPU sec, 3.638 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 295580, 28, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 304, 753)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1909)
[M::mem_pestat] mean and std.dev: (441.67, 420.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2487)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 380)
[M::mem_pestat] mean and std.dev: (159.90, 66.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 470)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (280, 630, 1396)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3628)
[M::mem_pestat] mean and std.dev: (924.82, 935.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4744)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 526, 959)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2481)
[M::mem_pestat] mean and std.dev: (540.26, 408.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3242)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 771338 sequences (100000276 bp) in 2.170 CPU sec, 2.170 real sec...
[M::mem_process_seqs] Processed 772370 reads in 202.150 CPU sec, 6.430 real sec
[M::mem_process_seqs] Processed 770268 reads in 137.052 CPU sec, 4.342 real sec
sorting block 110, #reads = 1084975 mem = 536884182 peak = 747048960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 296097, 25, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 317, 868)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2292)
[M::mem_pestat] mean and std.dev: (450.33, 468.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3004)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 146, 198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 374)
[M::mem_pestat] mean and std.dev: (158.49, 64.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 462)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 719, 909)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2355)
[M::mem_pestat] mean and std.dev: (675.52, 594.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3078)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 331, 734)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1800)
[M::mem_pestat] mean and std.dev: (465.26, 402.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2333)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 771702 sequences (100000009 bp) in 4.060 CPU sec, 4.352 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 295854, 42, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (133, 263, 1466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4132)
[M::mem_pestat] mean and std.dev: (597.15, 760.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5465)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 377)
[M::mem_pestat] mean and std.dev: (158.84, 65.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 466)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (137, 514, 1209)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3353)
[M::mem_pestat] mean and std.dev: (542.11, 595.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4425)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (251, 370, 1072)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2714)
[M::mem_pestat] mean and std.dev: (543.06, 589.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3535)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 771784 reads in 201.064 CPU sec, 6.394 real sec
sorting block 111, #reads = 1083208 mem = 536875747 peak = 747048960
[M::process] read 771060 sequences (100000000 bp) in 2.221 CPU sec, 2.293 real sec...
[M::mem_process_seqs] Processed 771338 reads in 137.872 CPU sec, 4.363 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 295624, 32, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 312, 1128)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3020)
[M::mem_pestat] mean and std.dev: (580.00, 648.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3966)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 146, 198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 374)
[M::mem_pestat] mean and std.dev: (158.48, 64.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 462)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 415, 852)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2238)
[M::mem_pestat] mean and std.dev: (479.10, 395.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2931)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 287, 1425)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3919)
[M::mem_pestat] mean and std.dev: (698.98, 876.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5166)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 112, #reads = 1084539 mem = 536887151 peak = 747048960
[M::process] read 771004 sequences (100000172 bp) in 3.570 CPU sec, 3.864 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 295336, 44, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 233, 437)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 963)
[M::mem_pestat] mean and std.dev: (301.10, 205.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1226)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 374)
[M::mem_pestat] mean and std.dev: (158.54, 64.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 462)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (237, 766, 1625)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4401)
[M::mem_pestat] mean and std.dev: (836.42, 812.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5789)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 333, 860)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2188)
[M::mem_pestat] mean and std.dev: (533.92, 446.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2852)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 771702 reads in 206.696 CPU sec, 6.590 real sec
[M::process] read 771296 sequences (100000177 bp) in 2.308 CPU sec, 2.369 real sec...
[M::mem_process_seqs] Processed 771060 reads in 141.227 CPU sec, 4.472 real sec
sorting block 113, #reads = 1081436 mem = 536881680 peak = 747048960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 294345, 39, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 231, 784)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2054)
[M::mem_pestat] mean and std.dev: (423.85, 423.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2689)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 374)
[M::mem_pestat] mean and std.dev: (158.57, 64.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 462)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 507, 1729)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4813)
[M::mem_pestat] mean and std.dev: (600.28, 640.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6355)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 317, 1338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3658)
[M::mem_pestat] mean and std.dev: (574.98, 638.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4818)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 771104 sequences (100000017 bp) in 3.947 CPU sec, 4.192 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 294761, 30, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 277, 806)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2124)
[M::mem_pestat] mean and std.dev: (477.60, 481.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2783)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 146, 198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 374)
[M::mem_pestat] mean and std.dev: (158.33, 64.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 462)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 479, 1519)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4255)
[M::mem_pestat] mean and std.dev: (795.79, 784.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5623)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 260, 939)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2477)
[M::mem_pestat] mean and std.dev: (460.57, 471.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3246)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 771004 reads in 208.242 CPU sec, 6.670 real sec
[M::mem_process_seqs] Processed 771296 reads in 144.412 CPU sec, 4.576 real sec
sorting block 114, #reads = 1082959 mem = 536886691 peak = 747048960
[M::process] read 771018 sequences (100000093 bp) in 2.337 CPU sec, 2.481 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 294196, 32, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (143, 258, 796)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2102)
[M::mem_pestat] mean and std.dev: (425.94, 397.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2755)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 146, 198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 374)
[M::mem_pestat] mean and std.dev: (158.27, 64.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 462)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 546, 1487)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4117)
[M::mem_pestat] mean and std.dev: (770.33, 900.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5432)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 381, 1010)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2634)
[M::mem_pestat] mean and std.dev: (636.26, 627.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3446)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 115, #reads = 1079356 mem = 536889472 peak = 747048960
[M::process] read 770782 sequences (100000142 bp) in 3.477 CPU sec, 3.740 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (80, 294175, 38, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 291, 549)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1303)
[M::mem_pestat] mean and std.dev: (335.15, 229.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1680)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 374)
[M::mem_pestat] mean and std.dev: (158.27, 64.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 462)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (244, 541, 1253)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3271)
[M::mem_pestat] mean and std.dev: (776.67, 778.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4280)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 460, 1005)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2563)
[M::mem_pestat] mean and std.dev: (490.43, 357.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3342)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 771366 sequences (100000087 bp) in 2.030 CPU sec, 2.032 real sec...
[M::mem_process_seqs] Processed 771104 reads in 211.057 CPU sec, 6.718 real sec
[M::mem_process_seqs] Processed 771018 reads in 144.588 CPU sec, 4.594 real sec
sorting block 116, #reads = 1077779 mem = 536883033 peak = 747048960
[M::process] read 774632 sequences (100000186 bp) in 3.353 CPU sec, 3.617 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 294263, 27, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 400, 970)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2596)
[M::mem_pestat] mean and std.dev: (550.26, 529.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3409)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 146, 197)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 371)
[M::mem_pestat] mean and std.dev: (157.86, 63.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 458)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (576, 1134, 2130)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5238)
[M::mem_pestat] mean and std.dev: (1306.81, 1059.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6792)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 415, 795)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2029)
[M::mem_pestat] mean and std.dev: (469.84, 394.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2646)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 779946 sequences (100000153 bp) in 1.947 CPU sec, 1.948 real sec...
[M::mem_process_seqs] Processed 771366 reads in 130.646 CPU sec, 4.147 real sec
sorting block 117, #reads = 1076363 mem = 536891252 peak = 747048960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 293744, 29, 74)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 317, 1066)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2898)
[M::mem_pestat] mean and std.dev: (463.12, 450.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3814)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 146, 197)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 371)
[M::mem_pestat] mean and std.dev: (157.92, 63.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 458)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (86, 320, 892)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2504)
[M::mem_pestat] mean and std.dev: (465.15, 475.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3310)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 558, 1180)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3116)
[M::mem_pestat] mean and std.dev: (595.14, 504.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4084)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 294599, 41, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 350, 997)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2655)
[M::mem_pestat] mean and std.dev: (565.78, 593.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3484)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 145, 195)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 367)
[M::mem_pestat] mean and std.dev: (156.06, 62.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 453)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (140, 372, 1170)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3230)
[M::mem_pestat] mean and std.dev: (542.69, 661.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4260)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 365, 817)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2053)
[M::mem_pestat] mean and std.dev: (472.74, 408.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2671)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 777580 sequences (100000001 bp) in 2.510 CPU sec, 2.517 real sec...
[M::mem_process_seqs] Processed 770782 reads in 342.563 CPU sec, 10.912 real sec
sorting block 118, #reads = 1073901 mem = 536880554 peak = 747048960
[M::mem_process_seqs] Processed 774632 reads in 187.750 CPU sec, 5.985 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 297494, 31, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (144, 335, 747)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1953)
[M::mem_pestat] mean and std.dev: (451.40, 389.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2556)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (108, 142, 191)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 357)
[M::mem_pestat] mean and std.dev: (153.43, 61.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 440)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (436, 564, 3625)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10003)
[M::mem_pestat] mean and std.dev: (2113.71, 2729.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13192)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 328, 901)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2299)
[M::mem_pestat] mean and std.dev: (456.93, 448.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2998)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 777678 sequences (100000226 bp) in 3.935 CPU sec, 4.190 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 296862, 30, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 273, 926)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2472)
[M::mem_pestat] mean and std.dev: (438.12, 384.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3245)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (108, 143, 193)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 363)
[M::mem_pestat] mean and std.dev: (154.68, 62.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 448)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (142, 523, 1341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3739)
[M::mem_pestat] mean and std.dev: (673.69, 741.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4938)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 388, 1347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3617)
[M::mem_pestat] mean and std.dev: (735.50, 792.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4752)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 775870 sequences (100000030 bp) in 2.200 CPU sec, 2.210 real sec...
[M::mem_process_seqs] Processed 779946 reads in 226.657 CPU sec, 7.193 real sec
sorting block 119, #reads = 1064177 mem = 536879343 peak = 747048960
[M::mem_process_seqs] Processed 777580 reads in 156.484 CPU sec, 4.979 real sec
sorting block 120, #reads = 1070638 mem = 536882055 peak = 747048960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 296879, 34, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (144, 234, 798)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2106)
[M::mem_pestat] mean and std.dev: (440.17, 453.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2760)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (108, 144, 193)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 363)
[M::mem_pestat] mean and std.dev: (154.83, 62.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 448)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 526, 1748)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4892)
[M::mem_pestat] mean and std.dev: (1051.81, 1254.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6464)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 318, 1402)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3860)
[M::mem_pestat] mean and std.dev: (683.55, 695.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5089)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 775058 sequences (100000259 bp) in 3.244 CPU sec, 3.527 real sec...
[M::process] read 776676 sequences (100000105 bp) in 2.130 CPU sec, 2.131 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 296770, 38, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (135, 236, 885)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2385)
[M::mem_pestat] mean and std.dev: (428.15, 507.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3135)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 144, 194)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 364)
[M::mem_pestat] mean and std.dev: (155.61, 62.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 449)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (292, 632, 1421)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3679)
[M::mem_pestat] mean and std.dev: (772.35, 729.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4808)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 446, 948)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2482)
[M::mem_pestat] mean and std.dev: (524.71, 516.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3249)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 777678 reads in 227.547 CPU sec, 7.798 real sec
[M::mem_process_seqs] Processed 775870 reads in 148.945 CPU sec, 4.745 real sec
sorting block 121, #reads = 1075580 mem = 536890837 peak = 747048960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 296623, 31, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (117, 186, 639)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1683)
[M::mem_pestat] mean and std.dev: (337.07, 359.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2205)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 145, 196)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 370)
[M::mem_pestat] mean and std.dev: (156.62, 63.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 457)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 506, 1153)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3055)
[M::mem_pestat] mean and std.dev: (569.59, 550.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4006)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 524, 1258)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3324)
[M::mem_pestat] mean and std.dev: (650.08, 658.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4357)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 776100 sequences (100000185 bp) in 3.308 CPU sec, 3.539 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 297170, 37, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 376, 727)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1803)
[M::mem_pestat] mean and std.dev: (429.23, 316.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2341)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 144, 193)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 361)
[M::mem_pestat] mean and std.dev: (154.76, 61.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 445)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 395, 884)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2344)
[M::mem_pestat] mean and std.dev: (471.03, 381.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3074)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (143, 246, 718)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1868)
[M::mem_pestat] mean and std.dev: (377.39, 372.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2443)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 776744 sequences (100000069 bp) in 2.100 CPU sec, 2.098 real sec...
[M::mem_process_seqs] Processed 775058 reads in 221.177 CPU sec, 7.252 real sec
sorting block 122, #reads = 1076319 mem = 536880754 peak = 747048960
[M::mem_process_seqs] Processed 776676 reads in 144.141 CPU sec, 4.580 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 297434, 37, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 286, 768)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1970)
[M::mem_pestat] mean and std.dev: (438.25, 440.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2571)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 144, 194)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 364)
[M::mem_pestat] mean and std.dev: (155.31, 62.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 449)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (460, 1075, 2119)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5437)
[M::mem_pestat] mean and std.dev: (1360.25, 1150.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7096)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 277, 650)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1604)
[M::mem_pestat] mean and std.dev: (393.70, 306.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2081)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 123, #reads = 1079566 mem = 536879668 peak = 747048960
[M::process] read 775152 sequences (100000268 bp) in 3.162 CPU sec, 3.407 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 297034, 28, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 324, 2457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7069)
[M::mem_pestat] mean and std.dev: (1019.06, 1455.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9375)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (108, 144, 193)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 363)
[M::mem_pestat] mean and std.dev: (155.13, 62.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 448)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (105, 273, 1618)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4644)
[M::mem_pestat] mean and std.dev: (666.96, 896.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6157)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 292, 926)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2466)
[M::mem_pestat] mean and std.dev: (402.45, 438.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3236)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 774376 sequences (100000128 bp) in 2.139 CPU sec, 2.147 real sec...
[M::mem_process_seqs] Processed 776100 reads in 212.839 CPU sec, 6.779 real sec
[M::mem_process_seqs] Processed 776744 reads in 147.688 CPU sec, 4.690 real sec
sorting block 124, #reads = 1081578 mem = 536882984 peak = 747048960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 297120, 29, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (140, 359, 1316)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3668)
[M::mem_pestat] mean and std.dev: (566.84, 672.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4844)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 145, 195)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 367)
[M::mem_pestat] mean and std.dev: (156.48, 63.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 453)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (409, 910, 1687)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4243)
[M::mem_pestat] mean and std.dev: (1037.38, 970.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5521)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 260, 1159)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3119)
[M::mem_pestat] mean and std.dev: (503.37, 643.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4099)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 771590 sequences (100000266 bp) in 3.858 CPU sec, 4.088 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 295823, 33, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 348, 717)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1823)
[M::mem_pestat] mean and std.dev: (419.76, 327.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2376)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 145, 196)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 370)
[M::mem_pestat] mean and std.dev: (156.85, 63.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 457)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (109, 493, 1034)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2884)
[M::mem_pestat] mean and std.dev: (470.00, 436.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3809)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 372, 1116)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2988)
[M::mem_pestat] mean and std.dev: (552.83, 578.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3924)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 772708 sequences (100000144 bp) in 2.093 CPU sec, 2.099 real sec...
[M::mem_process_seqs] Processed 775152 reads in 208.359 CPU sec, 6.614 real sec
sorting block 125, #reads = 1076741 mem = 536885592 peak = 747048960
[M::mem_process_seqs] Processed 774376 reads in 139.848 CPU sec, 4.442 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 295102, 38, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 290, 695)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1687)
[M::mem_pestat] mean and std.dev: (453.55, 409.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2183)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 146, 198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 374)
[M::mem_pestat] mean and std.dev: (158.44, 64.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 462)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 461, 1462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3980)
[M::mem_pestat] mean and std.dev: (669.18, 890.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5239)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 308, 1089)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2931)
[M::mem_pestat] mean and std.dev: (579.32, 612.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3852)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 126, #reads = 1080551 mem = 536882569 peak = 747048960
[M::process] read 773770 sequences (100000081 bp) in 3.154 CPU sec, 3.376 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 296203, 25, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (144, 286, 668)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1716)
[M::mem_pestat] mean and std.dev: (417.23, 406.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2240)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 146, 197)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 371)
[M::mem_pestat] mean and std.dev: (157.81, 64.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 458)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (300, 518, 1252)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3156)
[M::mem_pestat] mean and std.dev: (694.30, 788.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4108)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 307, 1074)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2808)
[M::mem_pestat] mean and std.dev: (542.17, 524.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3675)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 772432 sequences (100000106 bp) in 2.120 CPU sec, 2.123 real sec...
[M::mem_process_seqs] Processed 771590 reads in 204.971 CPU sec, 6.526 real sec
[M::mem_process_seqs] Processed 772708 reads in 141.201 CPU sec, 4.476 real sec
sorting block 127, #reads = 1078925 mem = 536880483 peak = 747048960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 296118, 29, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 303, 867)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2273)
[M::mem_pestat] mean and std.dev: (399.78, 333.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2976)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 145, 196)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 370)
[M::mem_pestat] mean and std.dev: (157.18, 63.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 457)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (355, 633, 2228)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5974)
[M::mem_pestat] mean and std.dev: (895.04, 891.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7847)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 220, 788)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2026)
[M::mem_pestat] mean and std.dev: (443.23, 442.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2645)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 772578 sequences (100000010 bp) in 3.573 CPU sec, 3.796 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 295773, 35, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 323, 1197)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3255)
[M::mem_pestat] mean and std.dev: (705.07, 921.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4392)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 146, 198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 374)
[M::mem_pestat] mean and std.dev: (158.15, 64.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 462)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 497, 1365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3685)
[M::mem_pestat] mean and std.dev: (719.67, 697.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4845)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 419, 1476)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4070)
[M::mem_pestat] mean and std.dev: (764.42, 825.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5367)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 772302 sequences (100000209 bp) in 2.150 CPU sec, 2.153 real sec...
[M::mem_process_seqs] Processed 773770 reads in 213.985 CPU sec, 7.263 real sec
[M::mem_process_seqs] Processed 772432 reads in 138.174 CPU sec, 4.382 real sec
sorting block 128, #reads = 1080875 mem = 536878933 peak = 747048960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 296152, 39, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (139, 239, 844)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2254)
[M::mem_pestat] mean and std.dev: (499.07, 567.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2959)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 146, 197)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 371)
[M::mem_pestat] mean and std.dev: (158.00, 64.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 458)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (273, 547, 2685)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7509)
[M::mem_pestat] mean and std.dev: (1373.38, 1663.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9921)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 377, 673)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1659)
[M::mem_pestat] mean and std.dev: (402.02, 292.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2152)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 129, #reads = 1080542 mem = 536878334 peak = 747048960
[M::process] read 771988 sequences (100000099 bp) in 3.180 CPU sec, 3.399 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 295801, 29, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (121, 313, 1277)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3589)
[M::mem_pestat] mean and std.dev: (599.15, 667.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4745)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 146, 198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 374)
[M::mem_pestat] mean and std.dev: (158.08, 64.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 462)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (240, 611, 1167)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3021)
[M::mem_pestat] mean and std.dev: (717.61, 670.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3948)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 343, 1146)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3020)
[M::mem_pestat] mean and std.dev: (561.66, 531.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3957)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 771202 sequences (100000025 bp) in 2.092 CPU sec, 2.097 real sec...
[M::mem_process_seqs] Processed 772578 reads in 200.736 CPU sec, 6.390 real sec
[M::mem_process_seqs] Processed 772302 reads in 136.377 CPU sec, 4.325 real sec
sorting block 130, #reads = 1079883 mem = 536876136 peak = 747048960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 295479, 49, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 240, 867)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2297)
[M::mem_pestat] mean and std.dev: (423.34, 475.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3012)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 146, 198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 374)
[M::mem_pestat] mean and std.dev: (158.26, 64.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 462)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (250, 511, 1497)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3991)
[M::mem_pestat] mean and std.dev: (778.87, 825.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5238)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 379, 800)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1998)
[M::mem_pestat] mean and std.dev: (456.78, 340.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2597)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 771486 sequences (100000200 bp) in 3.772 CPU sec, 3.979 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 294757, 34, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 307, 800)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2062)
[M::mem_pestat] mean and std.dev: (421.60, 383.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2693)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 374)
[M::mem_pestat] mean and std.dev: (158.49, 64.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 462)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 413, 1156)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3054)
[M::mem_pestat] mean and std.dev: (754.18, 813.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4006)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 349, 960)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2510)
[M::mem_pestat] mean and std.dev: (480.05, 477.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3285)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 770664 sequences (100000090 bp) in 2.064 CPU sec, 2.071 real sec...
[M::mem_process_seqs] Processed 771988 reads in 201.696 CPU sec, 6.409 real sec
sorting block 131, #reads = 1080732 mem = 536884240 peak = 747048960
[M::mem_process_seqs] Processed 771202 reads in 138.182 CPU sec, 4.388 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 294541, 40, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 251, 625)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1459)
[M::mem_pestat] mean and std.dev: (387.16, 295.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1876)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 146, 198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 374)
[M::mem_pestat] mean and std.dev: (158.24, 64.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 462)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (239, 556, 1131)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2915)
[M::mem_pestat] mean and std.dev: (740.87, 675.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3807)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 376, 933)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2369)
[M::mem_pestat] mean and std.dev: (567.93, 560.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3087)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 770314 sequences (100000257 bp) in 3.174 CPU sec, 3.372 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 294278, 43, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 468, 1387)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3837)
[M::mem_pestat] mean and std.dev: (764.44, 828.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5062)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 374)
[M::mem_pestat] mean and std.dev: (158.68, 64.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 462)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (141, 440, 1315)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3663)
[M::mem_pestat] mean and std.dev: (884.14, 978.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4837)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 325, 852)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2222)
[M::mem_pestat] mean and std.dev: (510.03, 517.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2907)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 770514 sequences (100000111 bp) in 2.080 CPU sec, 2.085 real sec...
[M::mem_process_seqs] Processed 771486 reads in 209.264 CPU sec, 7.128 real sec
sorting block 132, #reads = 1080219 mem = 536879905 peak = 747048960
[M::mem_process_seqs] Processed 770664 reads in 137.609 CPU sec, 4.369 real sec
[M::process] read 212296 sequences (27458780 bp) in 1.089 CPU sec, 1.123 real sec...
sorting block 133, #reads = 1077772 mem = 536880198 peak = 747048960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 294645, 32, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 331, 1137)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3087)
[M::mem_pestat] mean and std.dev: (639.89, 695.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4062)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 374)
[M::mem_pestat] mean and std.dev: (158.62, 64.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 462)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 560, 1336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3626)
[M::mem_pestat] mean and std.dev: (659.70, 725.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4771)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 333, 686)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1728)
[M::mem_pestat] mean and std.dev: (412.36, 318.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2249)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (15, 81312, 7, 13)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 402, 2890)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8322)
[M::mem_pestat] mean and std.dev: (1257.86, 1874.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11038)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 146, 196)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 370)
[M::mem_pestat] mean and std.dev: (157.04, 63.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 457)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 373, 2697)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7683)
[M::mem_pestat] mean and std.dev: (1675.31, 2471.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11561)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 770314 reads in 138.183 CPU sec, 4.482 real sec
sorting block 134, #reads = 1079452 mem = 536877212 peak = 747048960
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 293935, 32, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 338, 1105)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2997)
[M::mem_pestat] mean and std.dev: (649.16, 669.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3943)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 374)
[M::mem_pestat] mean and std.dev: (158.48, 64.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 462)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (144, 1009, 1584)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4464)
[M::mem_pestat] mean and std.dev: (842.24, 736.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5904)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 366, 1138)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2980)
[M::mem_pestat] mean and std.dev: (526.18, 488.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3901)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 212296 reads in 144.792 CPU sec, 4.684 real sec
[M::mem_process_seqs] Processed 770514 reads in 169.734 CPU sec, 5.501 real sec
sorting block 135, #reads = 1077184 mem = 536886698 peak = 747048960
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000a06d1
  features: 1f8bfbff fffab20b
  extended: f1bf27eb 1b407f7e
  amd bits: 2c100800 00000121
     brand: Intel(R) Xeon(R) 6975P-C
threads: 31
algo: bwa-mem
license: sentieon:klib=31
reads: 145081792
overall: 71967019008 mem 28957.588 user 1347.671 sys 1017.276 real
[main] Version: 0.7.17-r1188
[main] CMD: /opt/conda/share/sentieon-202308.03-3/libexec/bwa mem -K 100000000 -Y -R @RG\tID:A23MHWWLT4.1136_81F-T1-TDNA-1_A23MHWWLT4_1.L008\tPU:L008\tSM:1136_81F-T1-TDNA-1_A23MHWWLT4_1\tLB:1136_81F-T1-TDNA-1_A23MHWWLT4_1\tDS:s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta\tPL:ILLUMINA -t 31 ./BWAIndex/Homo_sapiens_assembly38.fasta.64 1136_81F-T1-TDNA-1_A23MHWWLT4_1_R1.fastq.gz 1136_81F-T1-TDNA-1_A23MHWWLT4_1_R2.fastq.gz
[main] Real time: 1017.306 sec; CPU: 30305.262 sec
sorting block 136, #reads = 63198 mem = 31511919 peak = 747048960
uniq header count 1
merging 137 blocks
sw version: sentieon-genomics-202308.03
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000a06d1
  features: 1f8bfbff fffab20b
  extended: f1bf27eb 1b407f7e
  amd bits: 2c100800 00000121
     brand: Intel(R) Xeon(R) 6975P-C
threads: 31 max 384
algo: util-sort
license: sentieon:util=1
output file size: 8757376510
output reads: 147104465
bam_mem_sort: 137 calls 93.980 user 3.178 sys 97.436 real
bam_write: 137 calls 59.882 user 4.533 sys 70.271 real
execute: 1 calls 30.202 user 2.226 sys 1059.837 real
merge_files: 1 calls 30.184 user 2.181 sys 42.456 real
parse_chunk: 2177 calls 96.942 user 27.659 sys 127.421 real
read_chunk: 5947 calls 68.193 user 52.012 sys 885.182 real
sort_block: 1 calls 53.141 user 51.205 sys 864.201 real
write_chunk: 3768 calls 29.767 user 1.728 sys 41.230 real
overall: 4118556672 mem 1807.527 user 114.146 sys 1059.857 real
ls: cannot access '*.cram': No such file or directory