cmdline: /opt/conda/share/sentieon-202308.03-3/libexec/util sort -r Homo_sapiens_assembly38.fasta -t 31 -o 1136_27F-T1-TDNA-1_A23MHWWLT4_1.bam --sam2bam -
This software is licensed to bgold@natera.com by Sentieon Inc.
This software is licensed to bgold@natera.com by Sentieon Inc.
No more license available for sentieon:klib
version: sentieon-genomics-202308.03
No more license available for sentieon:klib
[M::bwa_idx_load_from_disk] read 3171 ALT contigs
No more license available for sentieon:klib
No more license available for sentieon:klib
No more license available for sentieon:klib
No more license available for sentieon:klib
No more license available for sentieon:klib
No more license available for sentieon:klib
No more license available for sentieon:klib
No more license available for sentieon:klib
No more license available for sentieon:klib
No more license available for sentieon:klib
No more license available for sentieon:klib
No more license available for sentieon:klib
No more license available for sentieon:klib
No more license available for sentieon:klib
No more license available for sentieon:klib
[M::main_mem] bwa index loaded in 1606.099 CPU sec, 1015.100 real sec
[M::process] read 696434 sequences (100000182 bp) in 0.976 CPU sec, 0.982 real sec...
[M::process] read 696644 sequences (100000277 bp) in 1.194 CPU sec, 1.206 real sec...
[M::process] read 698000 sequences (100000073 bp) in 1.208 CPU sec, 1.229 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 290502, 21, 90)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 407, 1157)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3047)
[M::mem_pestat] mean and std.dev: (532.59, 466.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3992)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 252, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 767)
[M::mem_pestat] mean and std.dev: (277.35, 139.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 967)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (623, 792, 1224)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2426)
[M::mem_pestat] mean and std.dev: (904.24, 470.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3027)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 344, 431)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 851)
[M::mem_pestat] mean and std.dev: (328.14, 171.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1061)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695108 sequences (100000187 bp) in 1.170 CPU sec, 1.212 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 291161, 27, 73)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 213, 634)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1560)
[M::mem_pestat] mean and std.dev: (293.92, 209.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2023)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 252, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 769)
[M::mem_pestat] mean and std.dev: (277.57, 140.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 970)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (43, 420, 1650)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4864)
[M::mem_pestat] mean and std.dev: (739.35, 762.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6471)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 296, 418)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 938)
[M::mem_pestat] mean and std.dev: (280.36, 151.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1198)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 291117, 28, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 294, 487)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1137)
[M::mem_pestat] mean and std.dev: (335.17, 220.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1462)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 246, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 754)
[M::mem_pestat] mean and std.dev: (271.98, 137.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 951)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (76, 243, 794)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2230)
[M::mem_pestat] mean and std.dev: (402.35, 425.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2948)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 250, 739)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1817)
[M::mem_pestat] mean and std.dev: (379.11, 358.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2356)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696434 reads in 205.245 CPU sec, 6.597 real sec
[M::mem_process_seqs] Processed 696644 reads in 140.304 CPU sec, 4.552 real sec
[M::mem_process_seqs] Processed 698000 reads in 152.168 CPU sec, 4.951 real sec
sorting block 0, #reads = 1088150 mem = 536882971 peak = 594546688
[M::process] read 697248 sequences (100000205 bp) in 1.744 CPU sec, 1.885 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 290687, 24, 75)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 328, 564)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1326)
[M::mem_pestat] mean and std.dev: (378.79, 295.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1707)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 257, 374)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 784)
[M::mem_pestat] mean and std.dev: (282.47, 142.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 989)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (309, 1071, 3468)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9786)
[M::mem_pestat] mean and std.dev: (2426.29, 2983.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14362)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 294, 487)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1081)
[M::mem_pestat] mean and std.dev: (332.45, 208.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1378)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696234 sequences (100000039 bp) in 1.332 CPU sec, 1.356 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 290563, 27, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 302, 532)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1244)
[M::mem_pestat] mean and std.dev: (321.83, 193.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1600)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 248, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 758)
[M::mem_pestat] mean and std.dev: (274.06, 138.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 956)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 671, 2586)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7400)
[M::mem_pestat] mean and std.dev: (1413.20, 1794.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9807)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 297, 600)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1382)
[M::mem_pestat] mean and std.dev: (344.27, 195.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1773)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695108 reads in 125.573 CPU sec, 3.992 real sec
sorting block 1, #reads = 1089903 mem = 536881532 peak = 902086656
[M::mem_process_seqs] Processed 697248 reads in 80.121 CPU sec, 2.524 real sec
[M::process] read 694802 sequences (100000278 bp) in 1.441 CPU sec, 1.474 real sec...
sorting block 2, #reads = 1088975 mem = 536878186 peak = 902086656
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 290765, 16, 78)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 287, 830)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2116)
[M::mem_pestat] mean and std.dev: (461.72, 483.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2759)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 249, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 757)
[M::mem_pestat] mean and std.dev: (274.87, 137.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 954)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (483, 805, 1757)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4305)
[M::mem_pestat] mean and std.dev: (762.14, 532.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5579)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 311, 521)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1189)
[M::mem_pestat] mean and std.dev: (340.23, 200.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1523)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695008 sequences (100000074 bp) in 1.633 CPU sec, 1.900 real sec...
[M::process] read 694778 sequences (100000243 bp) in 1.190 CPU sec, 1.191 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (76, 289819, 30, 87)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 356, 741)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1853)
[M::mem_pestat] mean and std.dev: (418.52, 336.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2409)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 254, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 760)
[M::mem_pestat] mean and std.dev: (278.24, 138.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 957)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (339, 444, 824)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1794)
[M::mem_pestat] mean and std.dev: (450.29, 233.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2279)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (283, 325, 667)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1435)
[M::mem_pestat] mean and std.dev: (410.53, 258.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1819)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696234 reads in 125.774 CPU sec, 3.999 real sec
[M::mem_process_seqs] Processed 694802 reads in 79.766 CPU sec, 2.536 real sec
sorting block 3, #reads = 1087806 mem = 536877722 peak = 902086656
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 290124, 15, 74)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 298, 587)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1365)
[M::mem_pestat] mean and std.dev: (341.67, 238.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1754)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 254, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 765)
[M::mem_pestat] mean and std.dev: (278.17, 138.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 964)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (243, 244, 672)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1530)
[M::mem_pestat] mean and std.dev: (313.00, 181.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1959)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 297, 621)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1493)
[M::mem_pestat] mean and std.dev: (331.16, 232.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1929)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 693830 sequences (100000267 bp) in 1.824 CPU sec, 1.924 real sec...
[M::process] read 694176 sequences (100000157 bp) in 1.200 CPU sec, 1.199 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (82, 289980, 22, 76)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 302, 716)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1796)
[M::mem_pestat] mean and std.dev: (390.75, 324.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2336)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 253, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 754)
[M::mem_pestat] mean and std.dev: (277.01, 137.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 949)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 549, 1426)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3846)
[M::mem_pestat] mean and std.dev: (911.90, 1104.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5331)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 297, 450)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 954)
[M::mem_pestat] mean and std.dev: (317.40, 204.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1206)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695008 reads in 125.501 CPU sec, 3.997 real sec
[M::mem_process_seqs] Processed 694778 reads in 79.193 CPU sec, 2.520 real sec
sorting block 4, #reads = 1087691 mem = 536879637 peak = 902086656
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 289852, 28, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 274, 1000)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2680)
[M::mem_pestat] mean and std.dev: (485.68, 547.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3520)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 255, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 761)
[M::mem_pestat] mean and std.dev: (279.47, 138.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 958)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (434, 756, 1178)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2666)
[M::mem_pestat] mean and std.dev: (832.27, 611.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3410)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 288, 440)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 988)
[M::mem_pestat] mean and std.dev: (285.11, 154.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1262)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694438 sequences (100000148 bp) in 1.884 CPU sec, 1.998 real sec...
[M::process] read 696000 sequences (100000152 bp) in 1.220 CPU sec, 1.224 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 290457, 24, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 277, 868)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2166)
[M::mem_pestat] mean and std.dev: (419.29, 366.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2815)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 254, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 752)
[M::mem_pestat] mean and std.dev: (277.27, 136.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 946)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (268, 415, 1742)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4690)
[M::mem_pestat] mean and std.dev: (909.88, 917.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6164)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 315, 543)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1203)
[M::mem_pestat] mean and std.dev: (301.59, 171.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1533)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 693830 reads in 125.197 CPU sec, 3.980 real sec
sorting block 5, #reads = 1086870 mem = 536879260 peak = 902086656
[M::mem_process_seqs] Processed 694176 reads in 78.984 CPU sec, 2.509 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 289884, 26, 82)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 385, 709)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1795)
[M::mem_pestat] mean and std.dev: (472.40, 383.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2338)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
sorting block 6, #reads = 1086945 mem = 536879083 peak = 902086656
[M::mem_pestat] (25, 50, 75) percentile: (169, 254, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 763)
[M::mem_pestat] mean and std.dev: (278.65, 139.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 961)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (318, 572, 1445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3699)
[M::mem_pestat] mean and std.dev: (772.00, 671.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4826)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 333, 547)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1253)
[M::mem_pestat] mean and std.dev: (321.34, 186.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1606)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696510 sequences (100000084 bp) in 1.957 CPU sec, 2.074 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 290437, 19, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 308, 465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1033)
[M::mem_pestat] mean and std.dev: (299.84, 166.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1317)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 252, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 764)
[M::mem_pestat] mean and std.dev: (277.22, 139.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 963)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (429, 932, 1387)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3303)
[M::mem_pestat] mean and std.dev: (887.44, 634.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4261)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 323, 555)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1239)
[M::mem_pestat] mean and std.dev: (341.31, 209.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1581)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696740 sequences (100000058 bp) in 1.250 CPU sec, 1.248 real sec...
[M::mem_process_seqs] Processed 694438 reads in 126.206 CPU sec, 4.016 real sec
[M::process] read 696142 sequences (100000136 bp) in 1.387 CPU sec, 1.393 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 290626, 27, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 282, 695)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1729)
[M::mem_pestat] mean and std.dev: (388.07, 363.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2246)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 253, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 769)
[M::mem_pestat] mean and std.dev: (277.16, 139.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 970)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (266, 400, 1079)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2705)
[M::mem_pestat] mean and std.dev: (581.72, 573.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3518)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 321, 856)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2186)
[M::mem_pestat] mean and std.dev: (528.34, 496.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2851)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696510 reads in 72.199 CPU sec, 2.452 real sec
sorting block 7, #reads = 1087515 mem = 536878284 peak = 902086656
[M::mem_process_seqs] Processed 696000 reads in 172.364 CPU sec, 5.647 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 290988, 28, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 315, 671)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1647)
[M::mem_pestat] mean and std.dev: (469.83, 378.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2135)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 252, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 766)
[M::mem_pestat] mean and std.dev: (276.62, 139.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 966)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (418, 632, 2236)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5872)
[M::mem_pestat] mean and std.dev: (877.23, 763.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7690)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 287, 1039)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2793)
[M::mem_pestat] mean and std.dev: (537.87, 436.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3670)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 8, #reads = 1087775 mem = 536879995 peak = 902086656
[M::process] read 695994 sequences (100000063 bp) in 2.076 CPU sec, 2.226 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (85, 290573, 22, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 228, 400)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 854)
[M::mem_pestat] mean and std.dev: (279.19, 182.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1081)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 253, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 767)
[M::mem_pestat] mean and std.dev: (277.32, 139.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 967)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (431, 818, 1357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3209)
[M::mem_pestat] mean and std.dev: (869.71, 706.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4135)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 300, 641)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1555)
[M::mem_pestat] mean and std.dev: (362.39, 300.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2012)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696740 reads in 135.298 CPU sec, 4.306 real sec
[M::mem_process_seqs] Processed 696142 reads in 79.605 CPU sec, 2.516 real sec
[M::process] read 696188 sequences (100000187 bp) in 1.634 CPU sec, 1.712 real sec...
sorting block 9, #reads = 1089841 mem = 536877724 peak = 902086656
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 290352, 30, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 244, 470)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1108)
[M::mem_pestat] mean and std.dev: (318.46, 239.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1427)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 253, 368)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 770)
[M::mem_pestat] mean and std.dev: (277.50, 139.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 971)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (92, 573, 1035)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2921)
[M::mem_pestat] mean and std.dev: (575.90, 440.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3864)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 286, 587)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1405)
[M::mem_pestat] mean and std.dev: (351.31, 307.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1814)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694236 sequences (100000096 bp) in 1.956 CPU sec, 2.059 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 290164, 33, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 269, 597)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1349)
[M::mem_pestat] mean and std.dev: (329.42, 257.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1725)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 252, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 764)
[M::mem_pestat] mean and std.dev: (276.83, 138.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 963)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (139, 603, 1359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3799)
[M::mem_pestat] mean and std.dev: (863.91, 973.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5019)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 294, 434)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 910)
[M::mem_pestat] mean and std.dev: (294.69, 164.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1148)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695994 reads in 125.111 CPU sec, 3.977 real sec
[M::process] read 695186 sequences (100000045 bp) in 1.300 CPU sec, 1.298 real sec...
[M::mem_process_seqs] Processed 696188 reads in 80.218 CPU sec, 2.539 real sec
sorting block 10, #reads = 1089254 mem = 536880239 peak = 902086656
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 289689, 24, 76)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 283, 716)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1812)
[M::mem_pestat] mean and std.dev: (374.70, 285.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2360)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 260, 373)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 777)
[M::mem_pestat] mean and std.dev: (282.66, 140.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 979)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (274, 506, 1011)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2485)
[M::mem_pestat] mean and std.dev: (588.74, 484.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3222)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 397, 1632)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4492)
[M::mem_pestat] mean and std.dev: (758.79, 831.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5922)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695648 sequences (100000067 bp) in 2.214 CPU sec, 2.334 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 290084, 24, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 288, 400)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 824)
[M::mem_pestat] mean and std.dev: (292.11, 163.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1036)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 253, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 759)
[M::mem_pestat] mean and std.dev: (277.03, 138.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 956)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (25, 320, 1287)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3811)
[M::mem_pestat] mean and std.dev: (421.86, 656.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5073)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 265, 574)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1310)
[M::mem_pestat] mean and std.dev: (356.71, 241.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1678)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694068 sequences (100000220 bp) in 1.330 CPU sec, 1.323 real sec...
[M::mem_process_seqs] Processed 694236 reads in 125.935 CPU sec, 4.001 real sec
[M::mem_process_seqs] Processed 695186 reads in 80.621 CPU sec, 2.558 real sec
sorting block 11, #reads = 1088464 mem = 536881196 peak = 902086656
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (76, 290234, 29, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (245, 309, 817)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1961)
[M::mem_pestat] mean and std.dev: (459.25, 362.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2533)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 251, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 758)
[M::mem_pestat] mean and std.dev: (275.93, 138.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 955)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (361, 674, 1293)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3157)
[M::mem_pestat] mean and std.dev: (655.68, 442.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4089)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 246, 488)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1124)
[M::mem_pestat] mean and std.dev: (314.11, 206.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1442)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695450 sequences (100000106 bp) in 2.248 CPU sec, 2.400 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 289819, 21, 74)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 286, 505)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1155)
[M::mem_pestat] mean and std.dev: (330.51, 214.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1480)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 256, 368)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 764)
[M::mem_pestat] mean and std.dev: (279.36, 138.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 962)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (245, 530, 1119)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2867)
[M::mem_pestat] mean and std.dev: (613.60, 477.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3741)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 250, 429)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 991)
[M::mem_pestat] mean and std.dev: (270.57, 176.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1272)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695648 reads in 125.428 CPU sec, 3.988 real sec
[M::process] read 695330 sequences (100000158 bp) in 1.446 CPU sec, 1.462 real sec...
sorting block 12, #reads = 1087607 mem = 536877684 peak = 902086656
[M::mem_process_seqs] Processed 694068 reads in 80.105 CPU sec, 2.528 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 289380, 20, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 285, 1078)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2878)
[M::mem_pestat] mean and std.dev: (581.44, 643.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3778)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 250, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 749)
[M::mem_pestat] mean and std.dev: (274.59, 136.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 943)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 491, 862)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2250)
[M::mem_pestat] mean and std.dev: (509.06, 471.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2944)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 366, 685)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1647)
[M::mem_pestat] mean and std.dev: (434.05, 325.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2128)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 13, #reads = 1088548 mem = 536881322 peak = 921989120
[M::process] read 696416 sequences (100000100 bp) in 2.190 CPU sec, 2.329 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 290644, 26, 72)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 351, 696)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1744)
[M::mem_pestat] mean and std.dev: (368.94, 243.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2268)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 251, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 755)
[M::mem_pestat] mean and std.dev: (276.02, 137.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 951)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 570, 881)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2289)
[M::mem_pestat] mean and std.dev: (681.20, 608.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3116)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 352, 771)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1879)
[M::mem_pestat] mean and std.dev: (445.26, 333.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2433)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695450 reads in 126.866 CPU sec, 4.034 real sec
[M::process] read 698148 sequences (100000147 bp) in 1.466 CPU sec, 1.480 real sec...
[M::mem_process_seqs] Processed 695330 reads in 81.059 CPU sec, 2.558 real sec
sorting block 14, #reads = 1086857 mem = 536878889 peak = 921989120
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 290847, 32, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 376, 714)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1806)
[M::mem_pestat] mean and std.dev: (445.29, 389.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2352)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 250, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 754)
[M::mem_pestat] mean and std.dev: (274.30, 137.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 950)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (146, 300, 883)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2357)
[M::mem_pestat] mean and std.dev: (564.13, 620.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3094)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 292, 731)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1793)
[M::mem_pestat] mean and std.dev: (447.22, 395.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2324)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696596 sequences (100000198 bp) in 2.280 CPU sec, 2.433 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 291209, 20, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 275, 649)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1597)
[M::mem_pestat] mean and std.dev: (414.74, 362.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2071)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 247, 356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 742)
[M::mem_pestat] mean and std.dev: (270.16, 133.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 935)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (509, 873, 1821)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4445)
[M::mem_pestat] mean and std.dev: (1009.00, 770.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5757)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 304, 619)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1495)
[M::mem_pestat] mean and std.dev: (394.81, 357.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1933)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696416 reads in 130.106 CPU sec, 4.138 real sec
[M::process] read 694424 sequences (100000146 bp) in 1.464 CPU sec, 1.475 real sec...
[M::mem_process_seqs] Processed 698148 reads in 84.106 CPU sec, 2.654 real sec
sorting block 15, #reads = 1086675 mem = 536881683 peak = 921989120
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (83, 290623, 37, 76)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 286, 446)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 910)
[M::mem_pestat] mean and std.dev: (318.64, 183.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1142)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 250, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 751)
[M::mem_pestat] mean and std.dev: (273.53, 135.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 946)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (135, 353, 1070)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2940)
[M::mem_pestat] mean and std.dev: (476.68, 545.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3875)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (242, 351, 656)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1484)
[M::mem_pestat] mean and std.dev: (404.88, 253.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1898)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697046 sequences (100000244 bp) in 2.324 CPU sec, 2.481 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 289964, 19, 74)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 309, 821)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2037)
[M::mem_pestat] mean and std.dev: (506.81, 418.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2645)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 260, 375)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 785)
[M::mem_pestat] mean and std.dev: (283.32, 141.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 990)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (88, 347, 2055)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5989)
[M::mem_pestat] mean and std.dev: (1051.32, 1480.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7956)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 287, 420)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 894)
[M::mem_pestat] mean and std.dev: (325.94, 204.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1146)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696596 reads in 128.020 CPU sec, 4.079 real sec
[M::mem_process_seqs] Processed 694424 reads in 81.679 CPU sec, 2.583 real sec
[M::process] read 696488 sequences (100000208 bp) in 1.569 CPU sec, 1.601 real sec...
sorting block 16, #reads = 1087394 mem = 536879025 peak = 921989120
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (73, 290972, 17, 82)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 308, 867)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2283)
[M::mem_pestat] mean and std.dev: (501.67, 475.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2991)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 249, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 753)
[M::mem_pestat] mean and std.dev: (273.06, 136.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 949)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (587, 695, 1409)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3053)
[M::mem_pestat] mean and std.dev: (840.56, 441.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3875)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 313, 573)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1343)
[M::mem_pestat] mean and std.dev: (356.44, 257.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1728)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 17, #reads = 1085939 mem = 536880883 peak = 944693248
[M::process] read 696140 sequences (100000158 bp) in 2.303 CPU sec, 2.465 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 290870, 36, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 283, 812)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2086)
[M::mem_pestat] mean and std.dev: (461.24, 388.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2723)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 251, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 760)
[M::mem_pestat] mean and std.dev: (275.76, 137.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 958)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (503, 1026, 2406)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6212)
[M::mem_pestat] mean and std.dev: (1201.52, 1096.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8115)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 242, 401)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 851)
[M::mem_pestat] mean and std.dev: (254.45, 104.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1076)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697046 reads in 128.456 CPU sec, 4.089 real sec
[M::mem_process_seqs] Processed 696488 reads in 82.966 CPU sec, 2.618 real sec
[M::process] read 693994 sequences (100000162 bp) in 1.554 CPU sec, 1.589 real sec...
sorting block 18, #reads = 1088569 mem = 536879679 peak = 944693248
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (77, 290731, 47, 75)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 330, 718)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1728)
[M::mem_pestat] mean and std.dev: (401.50, 311.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2233)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 253, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 764)
[M::mem_pestat] mean and std.dev: (276.91, 138.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 963)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (375, 1016, 3096)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8538)
[M::mem_pestat] mean and std.dev: (1856.96, 1899.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11259)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (250, 373, 820)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1960)
[M::mem_pestat] mean and std.dev: (527.07, 429.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2530)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695284 sequences (100000038 bp) in 2.275 CPU sec, 2.429 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 289435, 29, 73)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 271, 489)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1055)
[M::mem_pestat] mean and std.dev: (302.46, 186.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1338)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 260, 373)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 775)
[M::mem_pestat] mean and std.dev: (282.67, 139.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 976)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (135, 783, 1077)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2961)
[M::mem_pestat] mean and std.dev: (763.18, 748.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3903)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 315, 586)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1346)
[M::mem_pestat] mean and std.dev: (398.32, 314.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1726)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696140 reads in 127.674 CPU sec, 4.065 real sec
[M::mem_process_seqs] Processed 693994 reads in 81.687 CPU sec, 2.579 real sec
[M::process] read 695312 sequences (100000162 bp) in 1.539 CPU sec, 1.564 real sec...
sorting block 19, #reads = 1087918 mem = 536878019 peak = 944693248
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 290224, 18, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 269, 425)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 939)
[M::mem_pestat] mean and std.dev: (305.80, 205.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1196)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 253, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 762)
[M::mem_pestat] mean and std.dev: (277.18, 138.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 960)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 741, 1324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3554)
[M::mem_pestat] mean and std.dev: (679.00, 541.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4669)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (259, 341, 704)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1594)
[M::mem_pestat] mean and std.dev: (484.52, 372.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2039)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695430 sequences (100000187 bp) in 2.288 CPU sec, 2.446 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (74, 290174, 27, 80)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 346, 796)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2066)
[M::mem_pestat] mean and std.dev: (395.52, 290.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2701)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 252, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 752)
[M::mem_pestat] mean and std.dev: (275.25, 136.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 947)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (555, 646, 2120)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5250)
[M::mem_pestat] mean and std.dev: (1228.92, 1501.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7236)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (236, 401, 688)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1592)
[M::mem_pestat] mean and std.dev: (425.97, 292.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2044)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695284 reads in 127.469 CPU sec, 4.057 real sec
[M::mem_process_seqs] Processed 695312 reads in 80.862 CPU sec, 2.552 real sec
[M::process] read 695592 sequences (100000054 bp) in 1.551 CPU sec, 1.588 real sec...
sorting block 20, #reads = 1087877 mem = 536878726 peak = 944693248
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (74, 289998, 20, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 281, 667)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1671)
[M::mem_pestat] mean and std.dev: (354.91, 324.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2173)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 250, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 749)
[M::mem_pestat] mean and std.dev: (274.48, 136.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 943)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (437, 763, 1452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3482)
[M::mem_pestat] mean and std.dev: (895.32, 766.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4497)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 345, 753)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1933)
[M::mem_pestat] mean and std.dev: (459.77, 393.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2523)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695274 sequences (100000177 bp) in 2.229 CPU sec, 2.338 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (74, 290413, 33, 73)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (131, 224, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 815)
[M::mem_pestat] mean and std.dev: (230.54, 115.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1043)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 250, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 749)
[M::mem_pestat] mean and std.dev: (274.55, 136.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 943)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 478, 1773)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4951)
[M::mem_pestat] mean and std.dev: (768.50, 768.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6540)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 303, 936)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2392)
[M::mem_pestat] mean and std.dev: (536.07, 540.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3120)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695430 reads in 125.863 CPU sec, 4.006 real sec
sorting block 21, #reads = 1087758 mem = 536880229 peak = 944693248
[M::mem_process_seqs] Processed 695592 reads in 80.529 CPU sec, 2.544 real sec
[M::process] read 695942 sequences (100000218 bp) in 1.544 CPU sec, 1.582 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (86, 290747, 21, 85)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 258, 484)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1130)
[M::mem_pestat] mean and std.dev: (281.43, 159.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1453)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 251, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 753)
[M::mem_pestat] mean and std.dev: (275.90, 138.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 948)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 367, 769)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1881)
[M::mem_pestat] mean and std.dev: (507.70, 441.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2437)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 283, 496)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1084)
[M::mem_pestat] mean and std.dev: (313.17, 161.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1378)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 22, #reads = 1088426 mem = 536878130 peak = 1002061824
[M::process] read 694128 sequences (100000193 bp) in 2.267 CPU sec, 2.419 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 290628, 30, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 235, 690)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1758)
[M::mem_pestat] mean and std.dev: (341.04, 289.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2292)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 252, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 755)
[M::mem_pestat] mean and std.dev: (275.02, 135.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 951)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (267, 874, 1223)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3135)
[M::mem_pestat] mean and std.dev: (976.90, 801.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4183)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 385, 588)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1356)
[M::mem_pestat] mean and std.dev: (382.31, 248.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1740)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695274 reads in 126.606 CPU sec, 4.034 real sec
[M::mem_process_seqs] Processed 695942 reads in 81.632 CPU sec, 2.578 real sec
[M::process] read 695522 sequences (100000146 bp) in 1.567 CPU sec, 1.609 real sec...
sorting block 23, #reads = 1087764 mem = 536884767 peak = 1002061824
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 289919, 20, 81)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 379, 693)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1671)
[M::mem_pestat] mean and std.dev: (375.02, 273.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2160)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 259, 371)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 771)
[M::mem_pestat] mean and std.dev: (280.74, 137.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 971)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (374, 719, 997)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2243)
[M::mem_pestat] mean and std.dev: (688.00, 451.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2866)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (269, 461, 693)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1541)
[M::mem_pestat] mean and std.dev: (517.34, 350.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1965)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694456 sequences (100000102 bp) in 2.287 CPU sec, 2.436 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 290591, 31, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 245, 500)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1178)
[M::mem_pestat] mean and std.dev: (294.56, 214.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1517)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 254, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 759)
[M::mem_pestat] mean and std.dev: (276.48, 136.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 956)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (118, 173, 563)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1453)
[M::mem_pestat] mean and std.dev: (236.19, 242.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1898)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (242, 282, 548)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1160)
[M::mem_pestat] mean and std.dev: (338.15, 193.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1466)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 694128 reads in 124.361 CPU sec, 3.972 real sec
[M::mem_process_seqs] Processed 695522 reads in 80.128 CPU sec, 2.538 real sec
[M::process] read 696860 sequences (100000144 bp) in 1.779 CPU sec, 1.878 real sec...
sorting block 24, #reads = 1088807 mem = 536877966 peak = 1002061824
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 289797, 25, 102)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 204, 540)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1280)
[M::mem_pestat] mean and std.dev: (339.53, 272.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1650)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 260, 374)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 782)
[M::mem_pestat] mean and std.dev: (282.88, 140.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 986)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (102, 374, 581)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1539)
[M::mem_pestat] mean and std.dev: (387.80, 299.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2018)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 264, 432)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 944)
[M::mem_pestat] mean and std.dev: (288.66, 179.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1200)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697166 sequences (100000233 bp) in 2.128 CPU sec, 2.264 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (74, 291050, 19, 76)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 296, 581)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1429)
[M::mem_pestat] mean and std.dev: (374.56, 282.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1853)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 250, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 756)
[M::mem_pestat] mean and std.dev: (274.27, 137.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 953)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 631, 2047)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5757)
[M::mem_pestat] mean and std.dev: (1009.42, 859.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7612)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 294, 763)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1881)
[M::mem_pestat] mean and std.dev: (433.04, 358.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2440)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 694456 reads in 126.804 CPU sec, 4.048 real sec
[M::mem_process_seqs] Processed 696860 reads in 81.863 CPU sec, 2.587 real sec
sorting block 25, #reads = 1088187 mem = 536881755 peak = 1002061824
[M::process] read 695304 sequences (100000068 bp) in 1.724 CPU sec, 1.795 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 291295, 23, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 339, 652)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1596)
[M::mem_pestat] mean and std.dev: (474.15, 382.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2068)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 248, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 747)
[M::mem_pestat] mean and std.dev: (272.42, 135.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 941)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (115, 411, 2122)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6136)
[M::mem_pestat] mean and std.dev: (1063.55, 1393.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8143)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 296, 764)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1888)
[M::mem_pestat] mean and std.dev: (468.26, 404.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2450)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 26, #reads = 1088549 mem = 536878239 peak = 1002061824
[M::process] read 695456 sequences (100000073 bp) in 2.248 CPU sec, 2.413 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 290576, 39, 93)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (142, 222, 395)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 901)
[M::mem_pestat] mean and std.dev: (244.91, 161.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1154)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 255, 368)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 768)
[M::mem_pestat] mean and std.dev: (278.96, 139.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 968)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (107, 440, 2587)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7547)
[M::mem_pestat] mean and std.dev: (1301.49, 1573.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10027)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 344, 533)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1209)
[M::mem_pestat] mean and std.dev: (321.11, 192.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1547)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697166 reads in 127.374 CPU sec, 4.068 real sec
[M::mem_process_seqs] Processed 695304 reads in 81.790 CPU sec, 2.588 real sec
[M::process] read 695012 sequences (100000169 bp) in 1.793 CPU sec, 1.873 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 290550, 20, 87)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 261, 677)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1697)
[M::mem_pestat] mean and std.dev: (395.15, 321.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2207)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
sorting block 27, #reads = 1089795 mem = 536880755 peak = 1002061824
[M::mem_pestat] (25, 50, 75) percentile: (168, 254, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 762)
[M::mem_pestat] mean and std.dev: (277.81, 138.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 960)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (228, 951, 2004)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5556)
[M::mem_pestat] mean and std.dev: (840.89, 830.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7332)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (233, 315, 1017)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2585)
[M::mem_pestat] mean and std.dev: (504.01, 496.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3369)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695476 sequences (100000030 bp) in 2.128 CPU sec, 2.267 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 290152, 24, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 346, 655)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1603)
[M::mem_pestat] mean and std.dev: (370.26, 264.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2077)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 256, 370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 772)
[M::mem_pestat] mean and std.dev: (280.28, 140.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 973)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (71, 317, 702)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1964)
[M::mem_pestat] mean and std.dev: (364.14, 414.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2595)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 292, 575)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1313)
[M::mem_pestat] mean and std.dev: (400.70, 296.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1682)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695456 reads in 128.509 CPU sec, 4.103 real sec
[M::mem_process_seqs] Processed 695012 reads in 82.934 CPU sec, 2.633 real sec
[M::process] read 695504 sequences (100000187 bp) in 1.639 CPU sec, 1.677 real sec...
sorting block 28, #reads = 1088241 mem = 536879086 peak = 1002061824
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 289738, 35, 76)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 255, 547)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1279)
[M::mem_pestat] mean and std.dev: (358.32, 258.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1645)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 250, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 752)
[M::mem_pestat] mean and std.dev: (275.21, 137.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 947)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (357, 1184, 1892)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4962)
[M::mem_pestat] mean and std.dev: (1069.00, 866.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6497)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 311, 444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 970)
[M::mem_pestat] mean and std.dev: (291.38, 149.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1233)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695328 sequences (100000273 bp) in 2.210 CPU sec, 2.342 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 290420, 37, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 284, 622)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1528)
[M::mem_pestat] mean and std.dev: (395.22, 316.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1981)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 250, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 746)
[M::mem_pestat] mean and std.dev: (274.02, 135.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 939)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (269, 883, 2445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6797)
[M::mem_pestat] mean and std.dev: (1275.57, 1378.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8973)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 385, 660)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1550)
[M::mem_pestat] mean and std.dev: (435.60, 332.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1995)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695476 reads in 130.269 CPU sec, 4.148 real sec
[M::process] read 698632 sequences (100000031 bp) in 1.463 CPU sec, 1.486 real sec...
sorting block 29, #reads = 1086809 mem = 536880422 peak = 1002061824
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 290023, 29, 81)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 262, 581)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1409)
[M::mem_pestat] mean and std.dev: (312.93, 242.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1823)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 250, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 749)
[M::mem_pestat] mean and std.dev: (274.69, 136.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 943)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (312, 576, 1413)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3615)
[M::mem_pestat] mean and std.dev: (770.55, 657.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4716)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 294, 425)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 903)
[M::mem_pestat] mean and std.dev: (274.00, 132.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1142)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699680 sequences (100000124 bp) in 1.559 CPU sec, 1.567 real sec...
[M::mem_process_seqs] Processed 695328 reads in 77.746 CPU sec, 2.656 real sec
[M::mem_process_seqs] Processed 695504 reads in 182.766 CPU sec, 5.994 real sec
sorting block 30, #reads = 1086221 mem = 536876091 peak = 1002061824
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 291481, 22, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 321, 638)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1474)
[M::mem_pestat] mean and std.dev: (403.27, 262.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1892)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 240, 350)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 728)
[M::mem_pestat] mean and std.dev: (266.33, 134.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 917)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 968, 1138)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2980)
[M::mem_pestat] mean and std.dev: (871.14, 673.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3901)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 319, 664)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1578)
[M::mem_pestat] mean and std.dev: (438.75, 355.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2035)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701364 sequences (100000041 bp) in 2.246 CPU sec, 2.396 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 292194, 13, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 316, 665)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1659)
[M::mem_pestat] mean and std.dev: (423.13, 354.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2156)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 240, 357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 751)
[M::mem_pestat] mean and std.dev: (269.73, 139.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 948)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (589, 761, 3249)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8569)
[M::mem_pestat] mean and std.dev: (1461.85, 1526.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11229)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 301, 496)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1058)
[M::mem_pestat] mean and std.dev: (329.33, 169.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1339)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698632 reads in 146.501 CPU sec, 4.665 real sec
[M::mem_process_seqs] Processed 699680 reads in 86.033 CPU sec, 2.718 real sec
[M::process] read 699272 sequences (100000010 bp) in 1.724 CPU sec, 1.795 real sec...
sorting block 31, #reads = 1087518 mem = 536879703 peak = 1002061824
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 293048, 16, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 282, 490)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1116)
[M::mem_pestat] mean and std.dev: (310.66, 188.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1429)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 234, 347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 727)
[M::mem_pestat] mean and std.dev: (262.54, 135.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 917)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (420, 549, 1687)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4221)
[M::mem_pestat] mean and std.dev: (642.64, 537.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5488)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 270, 444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 964)
[M::mem_pestat] mean and std.dev: (323.04, 181.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1224)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700542 sequences (100000060 bp) in 2.168 CPU sec, 2.323 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 291856, 26, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 306, 802)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2026)
[M::mem_pestat] mean and std.dev: (414.56, 343.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2638)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 241, 356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 748)
[M::mem_pestat] mean and std.dev: (269.39, 138.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 944)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (279, 454, 1265)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3237)
[M::mem_pestat] mean and std.dev: (706.27, 679.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4223)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 354, 537)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1241)
[M::mem_pestat] mean and std.dev: (318.79, 199.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1593)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701364 reads in 134.224 CPU sec, 4.274 real sec
[M::process] read 699612 sequences (100000235 bp) in 1.431 CPU sec, 1.440 real sec...
sorting block 32, #reads = 1088540 mem = 536878620 peak = 1002061824
[M::mem_process_seqs] Processed 699272 reads in 85.528 CPU sec, 2.708 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (73, 292186, 32, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 295, 611)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1397)
[M::mem_pestat] mean and std.dev: (388.48, 272.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1790)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 236, 348)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 728)
[M::mem_pestat] mean and std.dev: (264.08, 134.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 918)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (246, 617, 999)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2505)
[M::mem_pestat] mean and std.dev: (550.32, 380.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3258)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 287, 400)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 802)
[M::mem_pestat] mean and std.dev: (263.82, 109.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1003)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 33, #reads = 1089611 mem = 536880070 peak = 1013698560
[M::process] read 697106 sequences (100000150 bp) in 2.419 CPU sec, 2.574 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 291765, 28, 74)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 300, 931)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2383)
[M::mem_pestat] mean and std.dev: (495.20, 418.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3109)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 239, 353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 739)
[M::mem_pestat] mean and std.dev: (267.53, 137.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 932)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (631, 1425, 3991)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10711)
[M::mem_pestat] mean and std.dev: (2022.29, 1669.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14071)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 321, 563)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1289)
[M::mem_pestat] mean and std.dev: (317.78, 181.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1652)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696886 sequences (100000276 bp) in 1.400 CPU sec, 1.404 real sec...
[M::mem_process_seqs] Processed 700542 reads in 140.305 CPU sec, 4.462 real sec
[M::mem_process_seqs] Processed 699612 reads in 89.335 CPU sec, 2.832 real sec
sorting block 34, #reads = 1087865 mem = 536884800 peak = 1013698560
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 291118, 36, 83)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 232, 698)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1772)
[M::mem_pestat] mean and std.dev: (400.66, 388.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2309)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 248, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 765)
[M::mem_pestat] mean and std.dev: (276.01, 140.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 965)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 572, 1156)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3092)
[M::mem_pestat] mean and std.dev: (620.14, 501.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4060)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 323, 645)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1559)
[M::mem_pestat] mean and std.dev: (404.51, 316.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2016)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695728 sequences (100000256 bp) in 2.352 CPU sec, 2.496 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 290540, 29, 83)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 279, 555)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1339)
[M::mem_pestat] mean and std.dev: (370.71, 260.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1731)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 248, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 759)
[M::mem_pestat] mean and std.dev: (274.79, 138.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 957)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 748, 1194)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3222)
[M::mem_pestat] mean and std.dev: (707.80, 651.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4236)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 290, 821)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2099)
[M::mem_pestat] mean and std.dev: (466.75, 421.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2738)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695994 sequences (100000230 bp) in 1.420 CPU sec, 1.414 real sec...
[M::mem_process_seqs] Processed 697106 reads in 144.359 CPU sec, 4.594 real sec
[M::mem_process_seqs] Processed 696886 reads in 91.536 CPU sec, 2.903 real sec
sorting block 35, #reads = 1087141 mem = 536878559 peak = 1013698560
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 290504, 29, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 266, 459)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1053)
[M::mem_pestat] mean and std.dev: (274.83, 154.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1350)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 252, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 767)
[M::mem_pestat] mean and std.dev: (277.94, 140.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 967)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 483, 2288)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6432)
[M::mem_pestat] mean and std.dev: (1066.28, 1293.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8504)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 407, 1204)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3242)
[M::mem_pestat] mean and std.dev: (612.66, 611.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4261)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695802 sequences (100000160 bp) in 2.425 CPU sec, 2.589 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (77, 290645, 26, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (130, 240, 502)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1246)
[M::mem_pestat] mean and std.dev: (354.64, 316.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1623)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 247, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 751)
[M::mem_pestat] mean and std.dev: (274.45, 138.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 946)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (358, 484, 1189)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2851)
[M::mem_pestat] mean and std.dev: (624.61, 492.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3682)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (231, 378, 684)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1590)
[M::mem_pestat] mean and std.dev: (427.30, 318.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2043)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697800 sequences (100000015 bp) in 1.430 CPU sec, 1.425 real sec...
[M::mem_process_seqs] Processed 695728 reads in 144.419 CPU sec, 4.593 real sec
sorting block 36, #reads = 1085027 mem = 536879774 peak = 1013698560
[M::mem_process_seqs] Processed 695994 reads in 91.616 CPU sec, 2.904 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 290265, 33, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 367, 529)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1195)
[M::mem_pestat] mean and std.dev: (345.82, 215.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1528)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 250, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 763)
[M::mem_pestat] mean and std.dev: (276.90, 139.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 962)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (420, 790, 2921)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7923)
[M::mem_pestat] mean and std.dev: (1465.52, 1891.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10424)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 318, 516)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1142)
[M::mem_pestat] mean and std.dev: (346.69, 224.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1455)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 37, #reads = 1084831 mem = 536880133 peak = 1013698560
[M::process] read 704132 sequences (100000019 bp) in 2.690 CPU sec, 2.841 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 291627, 37, 75)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 294, 691)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1747)
[M::mem_pestat] mean and std.dev: (385.30, 335.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2275)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 244, 357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 745)
[M::mem_pestat] mean and std.dev: (271.20, 137.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 939)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (369, 1085, 2457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6633)
[M::mem_pestat] mean and std.dev: (1435.16, 1279.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8721)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 295, 434)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 894)
[M::mem_pestat] mean and std.dev: (320.80, 168.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1124)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695802 reads in 146.219 CPU sec, 4.649 real sec
[M::process] read 702460 sequences (100000008 bp) in 1.522 CPU sec, 1.528 real sec...
[M::mem_process_seqs] Processed 697800 reads in 94.095 CPU sec, 2.974 real sec
sorting block 38, #reads = 1084701 mem = 536877533 peak = 1013698560
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 293928, 43, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (141, 207, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 801)
[M::mem_pestat] mean and std.dev: (231.87, 158.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1021)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 228, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 702)
[M::mem_pestat] mean and std.dev: (255.13, 129.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 885)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (247, 463, 1460)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3886)
[M::mem_pestat] mean and std.dev: (648.11, 803.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5099)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 285, 611)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1435)
[M::mem_pestat] mean and std.dev: (400.87, 277.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1847)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700064 sequences (100000285 bp) in 2.223 CPU sec, 2.366 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 293413, 40, 74)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 251, 716)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1818)
[M::mem_pestat] mean and std.dev: (430.57, 420.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2369)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 233, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 714)
[M::mem_pestat] mean and std.dev: (259.08, 131.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 900)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 603, 1452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4002)
[M::mem_pestat] mean and std.dev: (660.24, 734.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5277)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 345, 1062)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2814)
[M::mem_pestat] mean and std.dev: (502.00, 465.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3690)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700850 sequences (100000078 bp) in 1.479 CPU sec, 1.485 real sec...
[M::mem_process_seqs] Processed 704132 reads in 158.122 CPU sec, 5.043 real sec
[M::mem_process_seqs] Processed 702460 reads in 98.357 CPU sec, 3.122 real sec
sorting block 39, #reads = 1082979 mem = 536882766 peak = 1013698560
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 292379, 40, 78)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (135, 195, 355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 795)
[M::mem_pestat] mean and std.dev: (217.17, 141.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1015)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 238, 350)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 732)
[M::mem_pestat] mean and std.dev: (264.95, 133.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 923)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (379, 736, 1100)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2542)
[M::mem_pestat] mean and std.dev: (711.95, 482.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3263)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 333, 829)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2103)
[M::mem_pestat] mean and std.dev: (437.07, 387.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2740)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699888 sequences (100000203 bp) in 2.516 CPU sec, 2.667 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 292714, 17, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 310, 609)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1479)
[M::mem_pestat] mean and std.dev: (388.02, 324.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1914)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 235, 345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 719)
[M::mem_pestat] mean and std.dev: (261.85, 132.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 906)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (136, 626, 1403)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3937)
[M::mem_pestat] mean and std.dev: (613.94, 572.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5204)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 328, 525)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1227)
[M::mem_pestat] mean and std.dev: (332.83, 215.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1578)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697726 sequences (100000111 bp) in 1.430 CPU sec, 1.438 real sec...
[M::mem_process_seqs] Processed 700064 reads in 150.079 CPU sec, 4.775 real sec
[M::mem_process_seqs] Processed 700850 reads in 94.005 CPU sec, 2.984 real sec
sorting block 40, #reads = 1083748 mem = 536879652 peak = 1013698560
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 291963, 16, 76)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 320, 530)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1226)
[M::mem_pestat] mean and std.dev: (327.08, 208.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1574)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 238, 350)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 732)
[M::mem_pestat] mean and std.dev: (264.95, 134.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 923)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (346, 781, 1292)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3184)
[M::mem_pestat] mean and std.dev: (762.81, 470.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4130)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 299, 541)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1295)
[M::mem_pestat] mean and std.dev: (342.41, 248.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1672)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697234 sequences (100000018 bp) in 2.375 CPU sec, 2.474 real sec...
[M::process] read 695466 sequences (100000291 bp) in 1.410 CPU sec, 1.415 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (76, 291552, 38, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 320, 518)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1166)
[M::mem_pestat] mean and std.dev: (363.11, 245.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1490)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 246, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 763)
[M::mem_pestat] mean and std.dev: (273.80, 139.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 963)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (430, 795, 2225)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5815)
[M::mem_pestat] mean and std.dev: (1339.24, 1422.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7610)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 333, 594)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1352)
[M::mem_pestat] mean and std.dev: (352.56, 224.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1731)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699888 reads in 147.839 CPU sec, 4.703 real sec
sorting block 41, #reads = 1086487 mem = 536882890 peak = 1013698560
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 290915, 33, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 329, 795)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1969)
[M::mem_pestat] mean and std.dev: (501.17, 431.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2556)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 246, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 755)
[M::mem_pestat] mean and std.dev: (273.31, 138.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 952)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 454, 2636)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7476)
[M::mem_pestat] mean and std.dev: (1315.61, 1417.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9896)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 264, 416)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 882)
[M::mem_pestat] mean and std.dev: (278.29, 155.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1115)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696750 sequences (100000037 bp) in 1.660 CPU sec, 1.666 real sec...
[M::mem_process_seqs] Processed 697234 reads in 80.126 CPU sec, 2.545 real sec
sorting block 42, #reads = 1084418 mem = 536882262 peak = 1013698560
[M::mem_process_seqs] Processed 697726 reads in 207.036 CPU sec, 6.590 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 290498, 33, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 315, 836)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2166)
[M::mem_pestat] mean and std.dev: (484.24, 453.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2831)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 253, 369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 773)
[M::mem_pestat] mean and std.dev: (279.70, 142.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 975)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (526, 671, 1540)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3568)
[M::mem_pestat] mean and std.dev: (780.79, 570.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4582)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 289, 370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 714)
[M::mem_pestat] mean and std.dev: (290.18, 136.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 886)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697096 sequences (100000216 bp) in 2.241 CPU sec, 2.428 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 290779, 24, 73)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 217, 633)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1571)
[M::mem_pestat] mean and std.dev: (270.12, 208.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2040)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 246, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 749)
[M::mem_pestat] mean and std.dev: (273.03, 138.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 944)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (293, 546, 1266)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3212)
[M::mem_pestat] mean and std.dev: (607.81, 428.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4185)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 336, 513)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1169)
[M::mem_pestat] mean and std.dev: (335.14, 219.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1497)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695466 reads in 158.454 CPU sec, 5.034 real sec
sorting block 43, #reads = 1084987 mem = 536879623 peak = 1013698560
[M::mem_process_seqs] Processed 696750 reads in 93.313 CPU sec, 2.952 real sec
[M::process] read 699674 sequences (100000016 bp) in 1.810 CPU sec, 1.887 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 291315, 28, 74)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (139, 218, 689)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1789)
[M::mem_pestat] mean and std.dev: (350.53, 316.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2339)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 245, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 755)
[M::mem_pestat] mean and std.dev: (273.58, 139.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 952)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (402, 755, 1248)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2940)
[M::mem_pestat] mean and std.dev: (746.92, 625.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3786)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 289, 1055)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2769)
[M::mem_pestat] mean and std.dev: (542.24, 563.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3626)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 44, #reads = 1084856 mem = 536878049 peak = 1013698560
[M::process] read 700902 sequences (100000087 bp) in 2.009 CPU sec, 2.141 real sec...
[M::process] read 699388 sequences (100000299 bp) in 1.370 CPU sec, 1.374 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (74, 291804, 32, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 266, 556)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1306)
[M::mem_pestat] mean and std.dev: (386.57, 309.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1681)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 237, 349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 727)
[M::mem_pestat] mean and std.dev: (264.94, 134.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 916)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (387, 873, 1708)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4350)
[M::mem_pestat] mean and std.dev: (896.21, 825.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5671)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 264, 501)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1179)
[M::mem_pestat] mean and std.dev: (287.24, 197.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1518)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697096 reads in 153.686 CPU sec, 4.903 real sec
[M::mem_process_seqs] Processed 699674 reads in 99.807 CPU sec, 3.167 real sec
sorting block 45, #reads = 1084550 mem = 536879644 peak = 1013698560
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 292608, 33, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 346, 2032)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5788)
[M::mem_pestat] mean and std.dev: (836.31, 1003.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7666)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 237, 349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 731)
[M::mem_pestat] mean and std.dev: (264.16, 134.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 922)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (70, 239, 1369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3967)
[M::mem_pestat] mean and std.dev: (803.21, 968.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5266)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 303, 511)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1111)
[M::mem_pestat] mean and std.dev: (370.20, 214.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1411)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697318 sequences (100000202 bp) in 2.683 CPU sec, 2.888 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 292245, 16, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 250, 421)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 965)
[M::mem_pestat] mean and std.dev: (243.06, 117.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1237)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 242, 356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 746)
[M::mem_pestat] mean and std.dev: (268.73, 136.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 941)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (343, 726, 1293)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3193)
[M::mem_pestat] mean and std.dev: (715.31, 510.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4143)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 301, 763)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1855)
[M::mem_pestat] mean and std.dev: (370.52, 289.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2401)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700902 reads in 142.155 CPU sec, 4.526 real sec
[M::process] read 700294 sequences (100000164 bp) in 1.521 CPU sec, 1.537 real sec...
[M::mem_process_seqs] Processed 699388 reads in 89.303 CPU sec, 2.824 real sec
sorting block 46, #reads = 1084380 mem = 536876837 peak = 1013698560
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 291212, 18, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 251, 398)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 792)
[M::mem_pestat] mean and std.dev: (261.73, 134.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 989)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 249, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 759)
[M::mem_pestat] mean and std.dev: (274.29, 138.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 957)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 839, 1632)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4496)
[M::mem_pestat] mean and std.dev: (913.00, 753.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5928)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 308, 741)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1877)
[M::mem_pestat] mean and std.dev: (412.40, 343.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2445)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698922 sequences (100000127 bp) in 2.271 CPU sec, 2.376 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 292374, 19, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 302, 803)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2023)
[M::mem_pestat] mean and std.dev: (418.59, 349.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2633)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 237, 345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 717)
[M::mem_pestat] mean and std.dev: (262.21, 131.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 903)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (267, 514, 1044)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2598)
[M::mem_pestat] mean and std.dev: (578.33, 505.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3375)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 307, 512)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1204)
[M::mem_pestat] mean and std.dev: (286.96, 148.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1550)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697398 sequences (100000280 bp) in 1.400 CPU sec, 1.402 real sec...
[M::mem_process_seqs] Processed 697318 reads in 141.561 CPU sec, 4.509 real sec
sorting block 47, #reads = 1089244 mem = 536877213 peak = 1013698560
[M::mem_process_seqs] Processed 700294 reads in 89.427 CPU sec, 2.835 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 292136, 37, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 310, 575)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1377)
[M::mem_pestat] mean and std.dev: (295.51, 191.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1778)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 241, 351)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 731)
[M::mem_pestat] mean and std.dev: (266.26, 133.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 921)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (407, 546, 1493)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3665)
[M::mem_pestat] mean and std.dev: (913.83, 797.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4751)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 309, 708)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1690)
[M::mem_pestat] mean and std.dev: (431.56, 315.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2181)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 48, #reads = 1086957 mem = 536878080 peak = 1015738368
[M::process] read 698258 sequences (100000056 bp) in 2.126 CPU sec, 2.238 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 291463, 33, 80)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 265, 665)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1677)
[M::mem_pestat] mean and std.dev: (373.42, 341.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2183)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 247, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 764)
[M::mem_pestat] mean and std.dev: (274.43, 139.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 964)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (260, 785, 2661)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7463)
[M::mem_pestat] mean and std.dev: (1312.73, 1509.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9864)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 296, 518)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1148)
[M::mem_pestat] mean and std.dev: (322.62, 181.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1463)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697824 sequences (100000282 bp) in 1.420 CPU sec, 1.421 real sec...
[M::mem_process_seqs] Processed 698922 reads in 138.376 CPU sec, 4.404 real sec
[M::mem_process_seqs] Processed 697398 reads in 88.064 CPU sec, 2.790 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 291500, 24, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 305, 793)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2023)
[M::mem_pestat] mean and std.dev: (379.72, 318.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2638)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
sorting block 49, #reads = 1088204 mem = 536878976 peak = 1015738368
[M::mem_pestat] (25, 50, 75) percentile: (162, 243, 354)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 738)
[M::mem_pestat] mean and std.dev: (268.60, 134.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 930)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (233, 533, 1824)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5006)
[M::mem_pestat] mean and std.dev: (822.21, 758.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6597)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 356, 985)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2571)
[M::mem_pestat] mean and std.dev: (563.33, 552.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3364)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697876 sequences (100000230 bp) in 2.808 CPU sec, 2.982 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 291738, 30, 72)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (138, 229, 402)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 930)
[M::mem_pestat] mean and std.dev: (246.33, 148.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1194)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 244, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 751)
[M::mem_pestat] mean and std.dev: (271.47, 137.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 947)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (124, 538, 1184)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3304)
[M::mem_pestat] mean and std.dev: (613.75, 585.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4364)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 301, 634)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1550)
[M::mem_pestat] mean and std.dev: (362.17, 265.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2008)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698258 reads in 144.457 CPU sec, 4.617 real sec
[M::mem_process_seqs] Processed 697824 reads in 92.673 CPU sec, 2.930 real sec
[M::process] read 697966 sequences (100000184 bp) in 2.021 CPU sec, 2.158 real sec...
sorting block 50, #reads = 1087222 mem = 536882720 peak = 1015738368
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (84, 291632, 33, 72)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 300, 641)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1547)
[M::mem_pestat] mean and std.dev: (386.60, 298.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2000)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 244, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 751)
[M::mem_pestat] mean and std.dev: (272.04, 138.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 947)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 467, 927)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2359)
[M::mem_pestat] mean and std.dev: (488.57, 422.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3075)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 281, 426)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 896)
[M::mem_pestat] mean and std.dev: (299.06, 169.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1131)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698706 sequences (100000137 bp) in 2.261 CPU sec, 2.427 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 291227, 29, 78)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 219, 533)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1267)
[M::mem_pestat] mean and std.dev: (313.30, 224.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1634)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 243, 356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 744)
[M::mem_pestat] mean and std.dev: (270.57, 137.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 938)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (385, 585, 1913)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4969)
[M::mem_pestat] mean and std.dev: (1086.54, 1125.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6497)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 321, 498)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1058)
[M::mem_pestat] mean and std.dev: (336.28, 198.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1338)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697876 reads in 152.226 CPU sec, 4.857 real sec
[M::mem_process_seqs] Processed 697966 reads in 97.703 CPU sec, 3.085 real sec
[M::process] read 704232 sequences (100000214 bp) in 1.696 CPU sec, 1.728 real sec...
sorting block 51, #reads = 1087184 mem = 536878355 peak = 1015738368
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 291285, 29, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 416, 954)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2430)
[M::mem_pestat] mean and std.dev: (512.47, 396.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3168)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 238, 350)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 728)
[M::mem_pestat] mean and std.dev: (265.66, 134.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 917)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 266, 844)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2198)
[M::mem_pestat] mean and std.dev: (461.33, 456.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2875)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (255, 400, 756)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1758)
[M::mem_pestat] mean and std.dev: (465.45, 358.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2259)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 52, #reads = 1084677 mem = 536879941 peak = 1015738368
[M::process] read 702984 sequences (100000260 bp) in 2.717 CPU sec, 2.878 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 293677, 25, 78)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 262, 407)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 909)
[M::mem_pestat] mean and std.dev: (286.71, 167.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1160)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 228, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 711)
[M::mem_pestat] mean and std.dev: (256.43, 130.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 897)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (577, 1594, 9187)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 26407)
[M::mem_pestat] mean and std.dev: (3501.32, 3675.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 35017)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 417, 1626)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4424)
[M::mem_pestat] mean and std.dev: (725.85, 754.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5823)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701714 sequences (100000178 bp) in 1.500 CPU sec, 1.495 real sec...
[M::mem_process_seqs] Processed 698706 reads in 165.932 CPU sec, 5.281 real sec
[M::mem_process_seqs] Processed 704232 reads in 106.957 CPU sec, 3.392 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 293266, 33, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 312, 852)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2170)
[M::mem_pestat] mean and std.dev: (427.00, 467.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2829)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 231, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 710)
[M::mem_pestat] mean and std.dev: (257.55, 129.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 895)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (315, 642, 1906)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5088)
[M::mem_pestat] mean and std.dev: (1056.97, 775.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6679)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 182, 377)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 823)
[M::mem_pestat] mean and std.dev: (212.33, 100.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1046)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 53, #reads = 1081988 mem = 536878823 peak = 1015738368
[M::process] read 703210 sequences (100000017 bp) in 2.901 CPU sec, 3.073 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 292950, 36, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 336, 946)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2468)
[M::mem_pestat] mean and std.dev: (463.25, 438.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3229)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 235, 351)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 739)
[M::mem_pestat] mean and std.dev: (264.04, 134.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 933)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 535, 2156)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6030)
[M::mem_pestat] mean and std.dev: (1197.06, 1605.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7967)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 295, 557)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1305)
[M::mem_pestat] mean and std.dev: (327.28, 202.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1679)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702984 reads in 161.925 CPU sec, 5.159 real sec
[M::process] read 700738 sequences (100000209 bp) in 1.693 CPU sec, 1.710 real sec...
[M::mem_process_seqs] Processed 701714 reads in 102.789 CPU sec, 3.254 real sec
sorting block 54, #reads = 1082306 mem = 536881097 peak = 1015738368
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 293626, 24, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 265, 1095)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2965)
[M::mem_pestat] mean and std.dev: (625.08, 782.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3900)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 229, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 700)
[M::mem_pestat] mean and std.dev: (255.00, 128.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 882)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 440, 656)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1540)
[M::mem_pestat] mean and std.dev: (422.50, 289.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1982)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 283, 872)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2288)
[M::mem_pestat] mean and std.dev: (410.62, 426.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2996)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698722 sequences (100000151 bp) in 2.233 CPU sec, 2.348 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 292782, 31, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 265, 428)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 946)
[M::mem_pestat] mean and std.dev: (310.08, 218.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1205)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 235, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 716)
[M::mem_pestat] mean and std.dev: (261.27, 130.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 902)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (134, 497, 5998)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 17726)
[M::mem_pestat] mean and std.dev: (2593.90, 3676.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 23590)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (247, 326, 503)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1015)
[M::mem_pestat] mean and std.dev: (334.69, 176.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1271)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698926 sequences (100000253 bp) in 1.490 CPU sec, 1.493 real sec...
[M::mem_process_seqs] Processed 703210 reads in 156.125 CPU sec, 4.982 real sec
[M::mem_process_seqs] Processed 700738 reads in 97.300 CPU sec, 3.096 real sec
sorting block 55, #reads = 1085938 mem = 536878315 peak = 1015738368
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 291763, 21, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 275, 489)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1137)
[M::mem_pestat] mean and std.dev: (316.97, 211.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1461)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 242, 354)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 740)
[M::mem_pestat] mean and std.dev: (268.12, 134.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 933)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (341, 936, 3276)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9146)
[M::mem_pestat] mean and std.dev: (1803.14, 1951.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12081)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 275, 852)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2238)
[M::mem_pestat] mean and std.dev: (441.72, 445.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2931)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698466 sequences (100000012 bp) in 2.743 CPU sec, 2.966 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 291902, 35, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 243, 599)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1455)
[M::mem_pestat] mean and std.dev: (346.11, 284.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1883)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 241, 351)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 731)
[M::mem_pestat] mean and std.dev: (266.32, 133.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 921)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (275, 411, 1179)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2987)
[M::mem_pestat] mean and std.dev: (668.21, 579.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3891)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (239, 337, 637)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1433)
[M::mem_pestat] mean and std.dev: (399.62, 275.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1831)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698722 reads in 152.022 CPU sec, 4.831 real sec
[M::process] read 697860 sequences (100000175 bp) in 1.529 CPU sec, 1.529 real sec...
sorting block 56, #reads = 1085718 mem = 536878364 peak = 1015738368
[M::mem_process_seqs] Processed 698926 reads in 95.785 CPU sec, 3.031 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 291579, 35, 79)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 225, 576)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1384)
[M::mem_pestat] mean and std.dev: (386.35, 313.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1788)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 243, 354)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 738)
[M::mem_pestat] mean and std.dev: (268.54, 134.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 930)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 644, 1310)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3496)
[M::mem_pestat] mean and std.dev: (789.97, 813.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4589)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 281, 701)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1719)
[M::mem_pestat] mean and std.dev: (395.61, 356.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2228)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 57, #reads = 1085940 mem = 536879871 peak = 1091223552
[M::process] read 697428 sequences (100000212 bp) in 2.940 CPU sec, 3.144 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 291346, 26, 77)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 299, 596)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1424)
[M::mem_pestat] mean and std.dev: (316.71, 210.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1838)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 244, 355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 739)
[M::mem_pestat] mean and std.dev: (269.53, 135.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 931)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 489, 1067)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2885)
[M::mem_pestat] mean and std.dev: (479.24, 383.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3794)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 309, 639)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1563)
[M::mem_pestat] mean and std.dev: (370.22, 315.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2025)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 376688 sequences (53942325 bp) in 0.970 CPU sec, 0.971 real sec...
[M::mem_process_seqs] Processed 698466 reads in 151.047 CPU sec, 4.818 real sec
[M::mem_process_seqs] Processed 697860 reads in 96.104 CPU sec, 3.057 real sec
sorting block 58, #reads = 1087100 mem = 536877303 peak = 1091223552
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 290862, 33, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 325, 692)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1764)
[M::mem_pestat] mean and std.dev: (392.00, 325.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2300)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 244, 357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 745)
[M::mem_pestat] mean and std.dev: (270.69, 136.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 939)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (353, 704, 953)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2153)
[M::mem_pestat] mean and std.dev: (718.66, 496.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2753)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 300, 610)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1458)
[M::mem_pestat] mean and std.dev: (363.48, 285.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1882)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 157509, 5, 24)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 299, 541)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1263)
[M::mem_pestat] mean and std.dev: (336.03, 239.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1624)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 241, 351)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 729)
[M::mem_pestat] mean and std.dev: (267.41, 134.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 918)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (230, 336, 608)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1364)
[M::mem_pestat] mean and std.dev: (399.30, 277.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1742)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697428 reads in 116.499 CPU sec, 3.786 real sec
[M::mem_process_seqs] Processed 376688 reads in 56.200 CPU sec, 1.820 real sec
sorting block 59, #reads = 1085083 mem = 536879607 peak = 1091223552
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000a06d1
  features: 1f8bfbff fffab20b
  extended: f1bf27eb 1b407f7e
  amd bits: 2c100800 00000121
     brand: Intel(R) Xeon(R) 6975P-C
threads: 31
algo: bwa-mem
license: sentieon:klib=31
reads: 65222068
overall: 69927301120 mem 8330.439 user 297.079 sys 1248.410 real
[main] Version: 0.7.17-r1188
[main] CMD: /opt/conda/share/sentieon-202308.03-3/libexec/bwa mem -K 100000000 -Y -R @RG\tID:A23MHWWLT4.1136_27F-T1-TDNA-1_A23MHWWLT4_1.L008\tPU:L008\tSM:1136_27F-T1-TDNA-1_A23MHWWLT4_1\tLB:1136_27F-T1-TDNA-1_A23MHWWLT4_1\tDS:s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta\tPL:ILLUMINA -t 31 ./BWAIndex/Homo_sapiens_assembly38.fasta.64 0004.1136_27F-T1-TDNA-1_A23MHWWLT4_1_R1.fastq.gz 0004.1136_27F-T1-TDNA-1_A23MHWWLT4_1_R2.fastq.gz
[main] Real time: 1248.451 sec; CPU: 8627.520 sec
sorting block 60, #reads = 555938 mem = 274912808 peak = 1091223552
uniq header count 1
merging 61 blocks
sw version: sentieon-genomics-202308.03
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000a06d1
  features: 1f8bfbff fffab20b
  extended: f1bf27eb 1b407f7e
  amd bits: 2c100800 00000121
     brand: Intel(R) Xeon(R) 6975P-C
threads: 31 max 192
algo: util-sort
license: sentieon:util=1
output file size: 3685213062
output reads: 65772268
bam_mem_sort: 61 calls 24.442 user 0.434 sys 25.016 real
bam_write: 61 calls 22.976 user 0.666 sys 23.863 real
execute: 1 calls 13.731 user 0.583 sys 1267.950 real
merge_files: 1 calls 13.716 user 0.561 sys 19.077 real
parse_chunk: 969 calls 33.085 user 8.528 sys 42.223 real
read_chunk: 2618 calls 23.248 user 24.615 sys 233.801 real
sort_block: 1 calls 19.156 user 24.097 sys 226.181 real
write_chunk: 1647 calls 13.386 user 0.403 sys 18.375 real
overall: 2797404160 mem 744.079 user 40.566 sys 1267.980 real
ls: cannot access '*.cram': No such file or directory