File Info

Filename
.command.log
Full Path
s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/ba/a6426e43f1535d457400300f251b0b/.command.log
Size
322.9 KB
Task
DAQ:SENTIEON_BWAMEM (1136_81F-T1-TDNA-1_A23MHWWLT4_1;L007;0001)
Attempt

Content

View in new tab 
  Downloading: s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/ba/a6426e43f1535d457400300f251b0b/.command.sh
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/23/1525a2d5ade2aa12faeea4fc75f881/1136_81F-T1-TDNA-1_A23MHWWLT4_1/1136_81F-T1-TDNA-1_A23MHWWLT4_1_R2.fastq.gz
  Downloading: s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta.fai
  Downloading: s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/BWAIndex
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/23/1525a2d5ade2aa12faeea4fc75f881/1136_81F-T1-TDNA-1_A23MHWWLT4_1/1136_81F-T1-TDNA-1_A23MHWWLT4_1_R1.fastq.gz
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/ba/a6426e43f1535d457400300f251b0b/.command.run
==> STAGING COMPLETE (7 inputs)

This software is licensed to bgold@natera.com by Sentieon Inc.
cmdline: /opt/conda/share/sentieon-202308.03-3/libexec/util sort -r Homo_sapiens_assembly38.fasta -t 31 -o 1136_81F-T1-TDNA-1_A23MHWWLT4_1.bam --sam2bam -
This software is licensed to bgold@natera.com by Sentieon Inc.
version: sentieon-genomics-202308.03
[M::bwa_idx_load_from_disk] read 3171 ALT contigs
[M::main_mem] bwa index loaded in 1991.097 CPU sec, 75.882 real sec
[M::process] read 775688 sequences (100000241 bp) in 1.703 CPU sec, 1.711 real sec...
[M::process] read 774354 sequences (100000101 bp) in 1.912 CPU sec, 1.920 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 296789, 25, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 404, 1019)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2721)
[M::mem_pestat] mean and std.dev: (538.83, 585.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3572)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 144, 196)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 370)
[M::mem_pestat] mean and std.dev: (156.54, 63.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 457)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (131, 469, 2318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6692)
[M::mem_pestat] mean and std.dev: (1008.96, 1352.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8879)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 312, 660)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1594)
[M::mem_pestat] mean and std.dev: (402.69, 328.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2061)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 773802 sequences (100000076 bp) in 1.871 CPU sec, 1.876 real sec...
[M::process] read 772938 sequences (100000002 bp) in 1.922 CPU sec, 1.935 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 296363, 32, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (136, 204, 656)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1696)
[M::mem_pestat] mean and std.dev: (321.55, 321.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2216)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 145, 196)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 370)
[M::mem_pestat] mean and std.dev: (157.08, 64.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 457)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (107, 319, 1761)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5069)
[M::mem_pestat] mean and std.dev: (841.17, 1069.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6723)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 398, 822)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2104)
[M::mem_pestat] mean and std.dev: (510.70, 437.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2745)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 775688 reads in 273.165 CPU sec, 8.652 real sec
[M::mem_process_seqs] Processed 774354 reads in 204.542 CPU sec, 6.591 real sec
sorting block 0, #reads = 1086576 mem = 536884309 peak = 586764288
[M::process] read 772402 sequences (100000141 bp) in 2.993 CPU sec, 3.300 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (76, 296750, 45, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 394, 780)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1934)
[M::mem_pestat] mean and std.dev: (472.14, 408.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2511)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 145, 197)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 373)
[M::mem_pestat] mean and std.dev: (157.47, 64.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 461)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (136, 392, 1060)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2908)
[M::mem_pestat] mean and std.dev: (537.12, 491.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3832)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (140, 245, 398)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 914)
[M::mem_pestat] mean and std.dev: (272.81, 184.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1172)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 770878 sequences (100000081 bp) in 2.101 CPU sec, 2.113 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 296454, 37, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 204, 320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 654)
[M::mem_pestat] mean and std.dev: (206.11, 85.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 821)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 146, 198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 376)
[M::mem_pestat] mean and std.dev: (158.13, 64.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 465)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 824, 4810)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 14006)
[M::mem_pestat] mean and std.dev: (2066.68, 2523.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 18604)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 336, 782)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1936)
[M::mem_pestat] mean and std.dev: (409.39, 290.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2513)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 295478, 26, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 297, 1052)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2764)
[M::mem_pestat] mean and std.dev: (592.33, 633.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3620)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 146, 198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 374)
[M::mem_pestat] mean and std.dev: (158.27, 64.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 462)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 645, 1099)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2919)
[M::mem_pestat] mean and std.dev: (623.87, 628.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3829)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 291, 756)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1938)
[M::mem_pestat] mean and std.dev: (397.88, 411.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2529)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 773802 reads in 404.126 CPU sec, 13.108 real sec
sorting block 1, #reads = 1085753 mem = 536880800 peak = 802246656
[M::mem_process_seqs] Processed 772938 reads in 322.886 CPU sec, 10.567 real sec
[M::mem_process_seqs] Processed 772402 reads in 365.586 CPU sec, 12.007 real sec
[M::process] read 770606 sequences (100000268 bp) in 2.658 CPU sec, 2.954 real sec...
sorting block 2, #reads = 1086953 mem = 536882002 peak = 832847872
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 294926, 43, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 332, 1056)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2742)
[M::mem_pestat] mean and std.dev: (578.74, 676.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3585)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 377)
[M::mem_pestat] mean and std.dev: (159.20, 65.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 466)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (281, 673, 1057)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2609)
[M::mem_pestat] mean and std.dev: (670.71, 430.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3385)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 309, 972)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2530)
[M::mem_pestat] mean and std.dev: (502.98, 535.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3309)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 769956 sequences (100000060 bp) in 2.811 CPU sec, 3.252 real sec...
[M::process] read 769844 sequences (100000120 bp) in 2.111 CPU sec, 2.154 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 294449, 38, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 323, 856)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2264)
[M::mem_pestat] mean and std.dev: (564.83, 607.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2995)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 380)
[M::mem_pestat] mean and std.dev: (159.52, 65.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 470)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 533, 1265)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3485)
[M::mem_pestat] mean and std.dev: (732.71, 803.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4595)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (142, 244, 415)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 961)
[M::mem_pestat] mean and std.dev: (242.78, 154.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1234)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 770878 reads in 294.267 CPU sec, 9.643 real sec
sorting block 3, #reads = 1085788 mem = 536881366 peak = 832847872
[M::mem_process_seqs] Processed 770606 reads in 208.429 CPU sec, 6.820 real sec
[M::process] read 769168 sequences (100000103 bp) in 3.065 CPU sec, 3.521 real sec...
sorting block 4, #reads = 1083320 mem = 536888438 peak = 873795584
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 294801, 36, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 334, 661)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1655)
[M::mem_pestat] mean and std.dev: (382.40, 297.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2152)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 380)
[M::mem_pestat] mean and std.dev: (159.62, 65.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 470)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 261, 885)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2317)
[M::mem_pestat] mean and std.dev: (494.94, 579.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3033)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 291, 1453)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4003)
[M::mem_pestat] mean and std.dev: (756.85, 953.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5278)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 769314 sequences (100000209 bp) in 2.310 CPU sec, 2.367 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 294970, 29, 82)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 332, 848)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2182)
[M::mem_pestat] mean and std.dev: (422.38, 387.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2849)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 148, 200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 380)
[M::mem_pestat] mean and std.dev: (159.95, 66.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 470)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (145, 412, 598)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1504)
[M::mem_pestat] mean and std.dev: (394.22, 272.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1957)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 358, 821)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2011)
[M::mem_pestat] mean and std.dev: (458.72, 392.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2606)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 769956 reads in 294.162 CPU sec, 9.672 real sec
[M::mem_process_seqs] Processed 769844 reads in 208.393 CPU sec, 6.812 real sec
sorting block 5, #reads = 1083402 mem = 536880618 peak = 873795584
[M::process] read 769272 sequences (100000101 bp) in 3.050 CPU sec, 3.295 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 294538, 34, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 348, 931)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2373)
[M::mem_pestat] mean and std.dev: (529.27, 483.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3094)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 381)
[M::mem_pestat] mean and std.dev: (160.47, 66.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 471)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (391, 729, 2132)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5614)
[M::mem_pestat] mean and std.dev: (1093.77, 1060.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7355)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 274, 1160)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3132)
[M::mem_pestat] mean and std.dev: (526.44, 556.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4118)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 768862 sequences (100000192 bp) in 2.580 CPU sec, 2.590 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 294403, 50, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 237, 1479)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4133)
[M::mem_pestat] mean and std.dev: (748.95, 1132.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5460)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 378)
[M::mem_pestat] mean and std.dev: (159.96, 65.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 467)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (275, 786, 1555)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4115)
[M::mem_pestat] mean and std.dev: (885.83, 736.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5395)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 300, 705)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1723)
[M::mem_pestat] mean and std.dev: (401.13, 333.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2232)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 769168 reads in 297.964 CPU sec, 9.731 real sec
[M::mem_process_seqs] Processed 769314 reads in 210.520 CPU sec, 6.886 real sec
sorting block 6, #reads = 1084718 mem = 536882347 peak = 873795584
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 294959, 50, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 458, 1071)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2895)
[M::mem_pestat] mean and std.dev: (508.07, 460.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3807)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 378)
[M::mem_pestat] mean and std.dev: (159.87, 65.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 467)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (88, 449, 858)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2398)
[M::mem_pestat] mean and std.dev: (425.96, 390.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3168)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 543, 1284)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3448)
[M::mem_pestat] mean and std.dev: (739.27, 662.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4530)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 768556 sequences (100000012 bp) in 3.582 CPU sec, 3.957 real sec...
[M::process] read 767392 sequences (100000017 bp) in 2.393 CPU sec, 2.418 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 294320, 33, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 272, 541)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1299)
[M::mem_pestat] mean and std.dev: (321.38, 250.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1678)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 381)
[M::mem_pestat] mean and std.dev: (160.54, 66.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 471)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 983, 2105)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5867)
[M::mem_pestat] mean and std.dev: (1326.25, 1436.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7748)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 308, 1028)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2714)
[M::mem_pestat] mean and std.dev: (632.23, 685.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3557)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 769272 reads in 295.849 CPU sec, 9.695 real sec
sorting block 7, #reads = 1083311 mem = 536886870 peak = 873795584
[M::mem_process_seqs] Processed 768862 reads in 208.882 CPU sec, 6.833 real sec
sorting block 8, #reads = 1084746 mem = 536883810 peak = 897462272
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 293882, 41, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 310, 761)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1987)
[M::mem_pestat] mean and std.dev: (412.83, 401.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2600)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 381)
[M::mem_pestat] mean and std.dev: (160.48, 66.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 471)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (381, 759, 1896)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4926)
[M::mem_pestat] mean and std.dev: (888.33, 801.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6441)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 319, 754)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1922)
[M::mem_pestat] mean and std.dev: (444.78, 399.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2506)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 767350 sequences (100000232 bp) in 3.156 CPU sec, 3.516 real sec...
[M::process] read 766996 sequences (100000261 bp) in 2.506 CPU sec, 2.537 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 293675, 35, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 345, 1213)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3301)
[M::mem_pestat] mean and std.dev: (646.23, 693.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4345)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 384)
[M::mem_pestat] mean and std.dev: (161.18, 66.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 475)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (232, 511, 1628)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4420)
[M::mem_pestat] mean and std.dev: (708.87, 707.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5816)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 385, 904)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2334)
[M::mem_pestat] mean and std.dev: (541.78, 473.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3049)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 768556 reads in 304.116 CPU sec, 10.121 real sec
[M::mem_process_seqs] Processed 767392 reads in 214.056 CPU sec, 7.166 real sec
sorting block 9, #reads = 1082537 mem = 536886908 peak = 897462272
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 293504, 20, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 342, 1293)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3493)
[M::mem_pestat] mean and std.dev: (628.56, 632.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4593)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 149, 202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 384)
[M::mem_pestat] mean and std.dev: (161.41, 66.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 475)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (284, 456, 731)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1625)
[M::mem_pestat] mean and std.dev: (495.84, 379.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2072)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 266, 1061)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2879)
[M::mem_pestat] mean and std.dev: (582.82, 653.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3788)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 767082 sequences (100000153 bp) in 3.464 CPU sec, 3.832 real sec...
[M::process] read 767706 sequences (100000095 bp) in 2.405 CPU sec, 2.536 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (73, 292823, 30, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 237, 598)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1500)
[M::mem_pestat] mean and std.dev: (375.03, 334.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1951)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 149, 202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 384)
[M::mem_pestat] mean and std.dev: (161.54, 66.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 475)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 602, 1265)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3367)
[M::mem_pestat] mean and std.dev: (690.65, 732.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4418)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (266, 322, 1411)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3701)
[M::mem_pestat] mean and std.dev: (603.69, 620.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4846)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 767350 reads in 305.133 CPU sec, 10.094 real sec
sorting block 10, #reads = 1082027 mem = 536879490 peak = 897462272
[M::mem_process_seqs] Processed 766996 reads in 212.655 CPU sec, 7.020 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 292899, 29, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 254, 671)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1619)
[M::mem_pestat] mean and std.dev: (411.74, 366.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2093)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 149, 202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 384)
[M::mem_pestat] mean and std.dev: (161.45, 66.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 475)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (416, 779, 1197)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2759)
[M::mem_pestat] mean and std.dev: (773.69, 536.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3540)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (240, 498, 964)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2412)
[M::mem_pestat] mean and std.dev: (624.06, 564.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3136)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 11, #reads = 1079239 mem = 536887769 peak = 897462272
[M::process] read 767508 sequences (100000048 bp) in 3.603 CPU sec, 3.886 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 293611, 38, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 219, 812)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2132)
[M::mem_pestat] mean and std.dev: (346.95, 305.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2792)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 381)
[M::mem_pestat] mean and std.dev: (160.79, 65.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 471)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (251, 695, 1150)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2948)
[M::mem_pestat] mean and std.dev: (629.62, 459.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3847)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 337, 1499)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4143)
[M::mem_pestat] mean and std.dev: (809.02, 997.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5465)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 767604 sequences (100000197 bp) in 2.605 CPU sec, 2.657 real sec...
[M::mem_process_seqs] Processed 767082 reads in 294.741 CPU sec, 9.815 real sec
[M::mem_process_seqs] Processed 767706 reads in 214.521 CPU sec, 7.167 real sec
sorting block 12, #reads = 1078319 mem = 536883282 peak = 897462272
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (74, 293105, 34, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (136, 323, 936)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2536)
[M::mem_pestat] mean and std.dev: (549.12, 621.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3336)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 381)
[M::mem_pestat] mean and std.dev: (160.78, 66.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 471)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (295, 806, 2639)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7327)
[M::mem_pestat] mean and std.dev: (1370.81, 1450.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9671)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 476, 981)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2527)
[M::mem_pestat] mean and std.dev: (656.77, 601.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3300)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 767672 sequences (100000144 bp) in 3.542 CPU sec, 4.060 real sec...
[M::process] read 768124 sequences (100000166 bp) in 2.740 CPU sec, 2.748 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (76, 293763, 27, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 304, 1349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3741)
[M::mem_pestat] mean and std.dev: (735.18, 845.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4937)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 384)
[M::mem_pestat] mean and std.dev: (160.94, 66.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 475)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 743, 1588)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4390)
[M::mem_pestat] mean and std.dev: (882.50, 1018.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5791)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 269, 954)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2464)
[M::mem_pestat] mean and std.dev: (478.36, 474.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3219)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 767508 reads in 289.063 CPU sec, 9.431 real sec
sorting block 13, #reads = 1077799 mem = 536880849 peak = 897462272
[M::mem_process_seqs] Processed 767604 reads in 208.689 CPU sec, 6.824 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 293389, 48, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (127, 214, 636)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1654)
[M::mem_pestat] mean and std.dev: (335.83, 340.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2163)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 149, 202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 384)
[M::mem_pestat] mean and std.dev: (161.09, 66.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 475)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (244, 508, 1371)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3625)
[M::mem_pestat] mean and std.dev: (808.49, 789.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4752)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 266, 546)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1294)
[M::mem_pestat] mean and std.dev: (325.27, 222.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1668)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 767928 sequences (100000144 bp) in 3.434 CPU sec, 3.846 real sec...
sorting block 14, #reads = 1079175 mem = 536881124 peak = 897462272
[M::process] read 774116 sequences (100000281 bp) in 3.003 CPU sec, 3.012 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 293448, 46, 78)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 278, 782)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2006)
[M::mem_pestat] mean and std.dev: (332.24, 265.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2618)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 381)
[M::mem_pestat] mean and std.dev: (160.49, 65.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 471)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 533, 990)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2568)
[M::mem_pestat] mean and std.dev: (567.29, 414.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3357)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 430, 1019)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2669)
[M::mem_pestat] mean and std.dev: (560.04, 518.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3494)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 767672 reads in 294.556 CPU sec, 9.638 real sec
[M::mem_process_seqs] Processed 768124 reads in 213.217 CPU sec, 6.970 real sec
sorting block 15, #reads = 1077675 mem = 536880062 peak = 897462272
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 293637, 46, 77)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 305, 1434)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3980)
[M::mem_pestat] mean and std.dev: (557.48, 643.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5253)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 149, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 381)
[M::mem_pestat] mean and std.dev: (160.85, 66.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 471)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (243, 549, 992)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2490)
[M::mem_pestat] mean and std.dev: (596.81, 515.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3239)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 289, 858)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2236)
[M::mem_pestat] mean and std.dev: (491.41, 498.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2925)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 774468 sequences (100000010 bp) in 4.045 CPU sec, 4.518 real sec...
[M::process] read 772450 sequences (100000269 bp) in 2.560 CPU sec, 2.638 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 296331, 32, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 242, 966)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2552)
[M::mem_pestat] mean and std.dev: (528.53, 571.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3345)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 145, 197)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 373)
[M::mem_pestat] mean and std.dev: (157.50, 64.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 461)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (314, 505, 1376)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3500)
[M::mem_pestat] mean and std.dev: (749.45, 748.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4562)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 299, 1246)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3370)
[M::mem_pestat] mean and std.dev: (713.78, 777.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4432)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 767928 reads in 291.782 CPU sec, 9.491 real sec
sorting block 16, #reads = 1078956 mem = 536884272 peak = 897462272
[M::mem_process_seqs] Processed 774116 reads in 211.293 CPU sec, 6.905 real sec
[M::process] read 771496 sequences (100000162 bp) in 3.279 CPU sec, 3.842 real sec...
sorting block 17, #reads = 1083421 mem = 536883653 peak = 897462272
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 295745, 25, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 275, 475)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1031)
[M::mem_pestat] mean and std.dev: (287.65, 195.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1309)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 146, 198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 376)
[M::mem_pestat] mean and std.dev: (158.34, 65.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 465)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 415, 876)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2278)
[M::mem_pestat] mean and std.dev: (570.08, 564.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2979)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 357, 1157)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3145)
[M::mem_pestat] mean and std.dev: (681.27, 717.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4139)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 771348 sequences (100000036 bp) in 2.878 CPU sec, 2.970 real sec...
[M::mem_process_seqs] Processed 772450 reads in 162.749 CPU sec, 5.276 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 296774, 34, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 415, 1277)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3497)
[M::mem_pestat] mean and std.dev: (691.94, 738.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4607)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 145, 197)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 373)
[M::mem_pestat] mean and std.dev: (157.33, 64.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 461)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 619, 1328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3556)
[M::mem_pestat] mean and std.dev: (753.90, 841.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4670)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 436, 1253)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3363)
[M::mem_pestat] mean and std.dev: (713.62, 765.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4418)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 295895, 45, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 287, 1298)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3512)
[M::mem_pestat] mean and std.dev: (624.10, 724.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4619)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 377)
[M::mem_pestat] mean and std.dev: (159.18, 65.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 466)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 553, 1291)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3455)
[M::mem_pestat] mean and std.dev: (690.26, 506.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4537)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 623, 3707)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10759)
[M::mem_pestat] mean and std.dev: (1989.66, 2605.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14285)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 774468 reads in 444.239 CPU sec, 14.538 real sec
[M::process] read 770940 sequences (100000038 bp) in 2.966 CPU sec, 2.976 real sec...
sorting block 18, #reads = 1087991 mem = 536877023 peak = 897462272
[M::mem_process_seqs] Processed 771496 reads in 242.388 CPU sec, 8.037 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 295980, 30, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 300, 749)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1947)
[M::mem_pestat] mean and std.dev: (383.05, 334.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2546)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 377)
[M::mem_pestat] mean and std.dev: (159.15, 65.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 466)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (286, 772, 2893)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8107)
[M::mem_pestat] mean and std.dev: (1501.27, 1446.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10714)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 533, 1295)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3487)
[M::mem_pestat] mean and std.dev: (600.00, 591.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4583)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 19, #reads = 1085710 mem = 536881024 peak = 897462272
[M::process] read 770790 sequences (100000184 bp) in 3.576 CPU sec, 4.301 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 295713, 35, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 319, 658)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1632)
[M::mem_pestat] mean and std.dev: (385.83, 329.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2119)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 380)
[M::mem_pestat] mean and std.dev: (159.54, 66.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 470)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (284, 861, 1295)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3317)
[M::mem_pestat] mean and std.dev: (692.75, 540.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4328)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 322, 1092)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2902)
[M::mem_pestat] mean and std.dev: (613.40, 675.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3807)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 771034 sequences (100000033 bp) in 2.534 CPU sec, 2.666 real sec...
[M::mem_process_seqs] Processed 771348 reads in 283.002 CPU sec, 9.511 real sec
[M::mem_process_seqs] Processed 770940 reads in 201.479 CPU sec, 6.586 real sec
sorting block 20, #reads = 1088954 mem = 536880234 peak = 897462272
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 295821, 53, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 213, 815)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2147)
[M::mem_pestat] mean and std.dev: (485.54, 544.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2813)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 377)
[M::mem_pestat] mean and std.dev: (159.33, 65.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 466)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 563, 1552)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4220)
[M::mem_pestat] mean and std.dev: (874.49, 762.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5554)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (142, 238, 582)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1462)
[M::mem_pestat] mean and std.dev: (352.16, 311.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1902)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 770598 sequences (100000086 bp) in 3.530 CPU sec, 4.028 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 295773, 32, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (136, 256, 493)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1207)
[M::mem_pestat] mean and std.dev: (269.64, 192.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1564)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 380)
[M::mem_pestat] mean and std.dev: (159.55, 66.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 470)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (345, 883, 1414)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3552)
[M::mem_pestat] mean and std.dev: (747.21, 560.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4621)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 445, 1494)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4026)
[M::mem_pestat] mean and std.dev: (825.69, 716.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5292)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 770074 sequences (100000096 bp) in 2.447 CPU sec, 2.510 real sec...
[M::mem_process_seqs] Processed 770790 reads in 277.650 CPU sec, 9.107 real sec
sorting block 21, #reads = 1085641 mem = 536881209 peak = 897462272
[M::mem_process_seqs] Processed 771034 reads in 199.488 CPU sec, 6.566 real sec
[M::process] read 769804 sequences (100000252 bp) in 3.554 CPU sec, 4.075 real sec...
sorting block 22, #reads = 1086329 mem = 536879199 peak = 897462272
[M::process] read 770094 sequences (100000083 bp) in 2.434 CPU sec, 2.549 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 295501, 22, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 282, 767)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1923)
[M::mem_pestat] mean and std.dev: (349.61, 270.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2501)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 383)
[M::mem_pestat] mean and std.dev: (160.19, 66.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 474)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (118, 327, 1284)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3616)
[M::mem_pestat] mean and std.dev: (515.45, 535.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4782)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 458, 1476)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3994)
[M::mem_pestat] mean and std.dev: (817.00, 793.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5253)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 770074 reads in 159.481 CPU sec, 5.195 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 295650, 37, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 311, 966)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2586)
[M::mem_pestat] mean and std.dev: (510.93, 517.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3396)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 380)
[M::mem_pestat] mean and std.dev: (159.96, 66.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 470)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (365, 807, 3527)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9851)
[M::mem_pestat] mean and std.dev: (2097.24, 2584.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13013)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 289, 772)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1962)
[M::mem_pestat] mean and std.dev: (407.24, 374.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2557)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (74, 295368, 33, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 351, 1113)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3015)
[M::mem_pestat] mean and std.dev: (749.27, 796.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3966)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 380)
[M::mem_pestat] mean and std.dev: (159.84, 66.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 470)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (43, 146, 1168)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3418)
[M::mem_pestat] mean and std.dev: (409.90, 592.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4543)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 379, 730)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1778)
[M::mem_pestat] mean and std.dev: (428.21, 332.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2302)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 768848 sequences (100000238 bp) in 2.525 CPU sec, 2.565 real sec...
[M::mem_process_seqs] Processed 770598 reads in 434.277 CPU sec, 14.189 real sec
sorting block 23, #reads = 1085988 mem = 536882696 peak = 897462272
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 294987, 32, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (136, 200, 514)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1270)
[M::mem_pestat] mean and std.dev: (273.21, 228.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1648)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::process] read 768722 sequences (100000025 bp) in 3.036 CPU sec, 3.088 real sec...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 383)
[M::mem_pestat] mean and std.dev: (160.28, 66.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 474)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (97, 331, 1441)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4129)
[M::mem_pestat] mean and std.dev: (771.66, 1060.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5473)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 312, 823)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2113)
[M::mem_pestat] mean and std.dev: (546.26, 485.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2758)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 770094 reads in 165.102 CPU sec, 5.504 real sec
sorting block 24, #reads = 1085733 mem = 536885621 peak = 903856128
[M::mem_process_seqs] Processed 769804 reads in 458.853 CPU sec, 15.169 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 294336, 26, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (138, 169, 763)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2013)
[M::mem_pestat] mean and std.dev: (426.25, 476.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2638)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 384)
[M::mem_pestat] mean and std.dev: (160.91, 66.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 475)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (331, 654, 748)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1582)
[M::mem_pestat] mean and std.dev: (538.54, 235.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1999)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 256, 508)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1178)
[M::mem_pestat] mean and std.dev: (330.47, 244.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1513)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 769120 sequences (100000133 bp) in 3.091 CPU sec, 3.536 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 294835, 40, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 667, 1456)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3932)
[M::mem_pestat] mean and std.dev: (758.13, 649.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5170)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 384)
[M::mem_pestat] mean and std.dev: (160.90, 66.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 475)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (257, 485, 708)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1610)
[M::mem_pestat] mean and std.dev: (503.76, 341.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2061)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (236, 632, 1514)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4070)
[M::mem_pestat] mean and std.dev: (956.33, 926.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5348)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 768048 sequences (100000148 bp) in 2.518 CPU sec, 2.546 real sec...
[M::mem_process_seqs] Processed 768848 reads in 319.488 CPU sec, 10.438 real sec
sorting block 25, #reads = 1085771 mem = 536878543 peak = 903856128
[M::mem_process_seqs] Processed 768722 reads in 202.374 CPU sec, 6.622 real sec
sorting block 26, #reads = 1084351 mem = 536878865 peak = 995180544
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 294245, 42, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 233, 634)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1600)
[M::mem_pestat] mean and std.dev: (370.64, 332.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2083)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 381)
[M::mem_pestat] mean and std.dev: (160.38, 66.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 471)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (350, 464, 1704)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4412)
[M::mem_pestat] mean and std.dev: (652.37, 773.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5766)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 515, 1119)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2949)
[M::mem_pestat] mean and std.dev: (806.41, 795.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3987)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 769192 sequences (100000154 bp) in 3.036 CPU sec, 3.543 real sec...
[M::process] read 768270 sequences (100000104 bp) in 2.881 CPU sec, 2.987 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 294130, 36, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 348, 1086)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2894)
[M::mem_pestat] mean and std.dev: (629.31, 668.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3798)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 384)
[M::mem_pestat] mean and std.dev: (161.24, 66.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 475)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (90, 280, 821)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2283)
[M::mem_pestat] mean and std.dev: (456.39, 587.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3014)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 259, 829)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2137)
[M::mem_pestat] mean and std.dev: (446.00, 461.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2791)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 769120 reads in 281.262 CPU sec, 9.247 real sec
[M::mem_process_seqs] Processed 768048 reads in 203.835 CPU sec, 6.709 real sec
sorting block 27, #reads = 1083075 mem = 536878415 peak = 995180544
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (82, 293753, 43, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 444, 795)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2029)
[M::mem_pestat] mean and std.dev: (460.19, 408.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2646)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 381)
[M::mem_pestat] mean and std.dev: (160.23, 66.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 471)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (279, 606, 1719)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4599)
[M::mem_pestat] mean and std.dev: (771.08, 683.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6039)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 308, 878)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2260)
[M::mem_pestat] mean and std.dev: (516.22, 499.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2951)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 767594 sequences (100000115 bp) in 3.687 CPU sec, 4.266 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 293781, 29, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 280, 820)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2142)
[M::mem_pestat] mean and std.dev: (450.66, 448.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2803)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 381)
[M::mem_pestat] mean and std.dev: (160.73, 66.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 471)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (146, 501, 1145)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3143)
[M::mem_pestat] mean and std.dev: (662.36, 679.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4142)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 468, 1282)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3498)
[M::mem_pestat] mean and std.dev: (572.32, 545.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4606)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 768138 sequences (100000242 bp) in 2.814 CPU sec, 2.888 real sec...
[M::mem_process_seqs] Processed 769192 reads in 283.248 CPU sec, 9.198 real sec
sorting block 28, #reads = 1082539 mem = 536878187 peak = 995180544
[M::mem_process_seqs] Processed 768270 reads in 206.275 CPU sec, 6.702 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (93, 293441, 38, 80)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 321, 746)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1906)
[M::mem_pestat] mean and std.dev: (403.89, 361.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2486)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 149, 202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 384)
[M::mem_pestat] mean and std.dev: (161.14, 66.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 475)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 685, 1380)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3696)
[M::mem_pestat] mean and std.dev: (945.32, 907.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4854)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 348, 653)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1557)
[M::mem_pestat] mean and std.dev: (404.23, 329.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2009)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 29, #reads = 1081892 mem = 536882444 peak = 995180544
[M::process] read 767668 sequences (100000208 bp) in 3.701 CPU sec, 4.281 real sec...
[M::process] read 767962 sequences (100000128 bp) in 2.618 CPU sec, 2.685 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (84, 293374, 39, 73)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 307, 823)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2145)
[M::mem_pestat] mean and std.dev: (487.41, 430.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2806)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 381)
[M::mem_pestat] mean and std.dev: (160.70, 66.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 471)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (264, 546, 951)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2325)
[M::mem_pestat] mean and std.dev: (629.44, 545.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3012)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 398, 934)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2384)
[M::mem_pestat] mean and std.dev: (512.82, 465.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3109)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 767594 reads in 287.005 CPU sec, 9.644 real sec
[M::mem_process_seqs] Processed 768138 reads in 205.360 CPU sec, 6.644 real sec
sorting block 30, #reads = 1080359 mem = 536882134 peak = 995180544
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 293463, 27, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 342, 805)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2095)
[M::mem_pestat] mean and std.dev: (469.23, 445.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2740)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 149, 202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 384)
[M::mem_pestat] mean and std.dev: (161.13, 66.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 475)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 391, 869)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2231)
[M::mem_pestat] mean and std.dev: (531.72, 498.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2912)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 336, 1178)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3200)
[M::mem_pestat] mean and std.dev: (569.47, 582.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4211)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 768722 sequences (100000247 bp) in 3.011 CPU sec, 3.574 real sec...
[M::process] read 768608 sequences (100000297 bp) in 2.968 CPU sec, 2.996 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 294070, 38, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 358, 1010)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2716)
[M::mem_pestat] mean and std.dev: (625.06, 607.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3569)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 384)
[M::mem_pestat] mean and std.dev: (161.15, 66.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 475)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (372, 543, 2101)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5559)
[M::mem_pestat] mean and std.dev: (1192.42, 1363.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7288)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 274, 987)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2575)
[M::mem_pestat] mean and std.dev: (519.70, 551.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3369)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 767668 reads in 281.880 CPU sec, 9.208 real sec
sorting block 31, #reads = 1080227 mem = 536880496 peak = 995180544
[M::mem_process_seqs] Processed 767962 reads in 204.122 CPU sec, 6.742 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 293770, 35, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 313, 743)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1825)
[M::mem_pestat] mean and std.dev: (414.51, 317.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2366)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 381)
[M::mem_pestat] mean and std.dev: (160.32, 66.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 471)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (145, 512, 1686)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4768)
[M::mem_pestat] mean and std.dev: (874.34, 1134.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6309)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 251, 589)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1435)
[M::mem_pestat] mean and std.dev: (330.66, 276.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1858)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 32, #reads = 1080971 mem = 536881805 peak = 995180544
[M::process] read 770498 sequences (100000229 bp) in 4.026 CPU sec, 4.663 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 293832, 37, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 239, 1066)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2886)
[M::mem_pestat] mean and std.dev: (493.24, 477.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3796)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 378)
[M::mem_pestat] mean and std.dev: (159.99, 65.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 467)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (254, 635, 1635)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4397)
[M::mem_pestat] mean and std.dev: (773.41, 882.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5778)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 320, 1028)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2716)
[M::mem_pestat] mean and std.dev: (517.53, 491.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3560)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 773952 sequences (100000029 bp) in 2.463 CPU sec, 2.642 real sec...
[M::mem_process_seqs] Processed 768722 reads in 283.968 CPU sec, 9.242 real sec
[M::mem_process_seqs] Processed 768608 reads in 208.146 CPU sec, 6.878 real sec
sorting block 33, #reads = 1080727 mem = 536879037 peak = 995180544
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 294158, 49, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (142, 247, 1044)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2848)
[M::mem_pestat] mean and std.dev: (475.09, 527.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3750)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 377)
[M::mem_pestat] mean and std.dev: (159.02, 65.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 466)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (122, 361, 706)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1874)
[M::mem_pestat] mean and std.dev: (318.40, 270.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2458)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 283, 550)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1248)
[M::mem_pestat] mean and std.dev: (295.64, 185.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1597)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 773372 sequences (100000168 bp) in 3.159 CPU sec, 3.777 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 296211, 37, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 410, 861)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2219)
[M::mem_pestat] mean and std.dev: (501.61, 477.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2898)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 145, 197)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 373)
[M::mem_pestat] mean and std.dev: (157.60, 64.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 461)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (254, 561, 1478)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3926)
[M::mem_pestat] mean and std.dev: (857.97, 954.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5150)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 396, 1103)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2927)
[M::mem_pestat] mean and std.dev: (515.98, 479.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3839)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 772368 sequences (100000216 bp) in 2.802 CPU sec, 2.912 real sec...
[M::mem_process_seqs] Processed 770498 reads in 286.086 CPU sec, 9.334 real sec
sorting block 34, #reads = 1079111 mem = 536879716 peak = 995180544
[M::mem_process_seqs] Processed 773952 reads in 206.126 CPU sec, 6.718 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 295934, 32, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (144, 257, 1158)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3186)
[M::mem_pestat] mean and std.dev: (573.15, 687.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4200)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 146, 197)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 373)
[M::mem_pestat] mean and std.dev: (157.85, 64.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 461)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 455, 1442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4032)
[M::mem_pestat] mean and std.dev: (779.76, 974.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5327)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 291, 908)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2304)
[M::mem_pestat] mean and std.dev: (476.81, 410.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3002)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 771170 sequences (100000168 bp) in 3.208 CPU sec, 3.776 real sec...
sorting block 35, #reads = 1085115 mem = 536881487 peak = 995180544
[M::process] read 770944 sequences (100000015 bp) in 2.450 CPU sec, 2.479 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 295869, 51, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 293, 653)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1597)
[M::mem_pestat] mean and std.dev: (334.56, 237.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2069)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 146, 199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 377)
[M::mem_pestat] mean and std.dev: (159.09, 65.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 466)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 374, 1024)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2754)
[M::mem_pestat] mean and std.dev: (419.33, 344.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3619)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (142, 343, 916)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2464)
[M::mem_pestat] mean and std.dev: (609.87, 626.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3238)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 773372 reads in 278.632 CPU sec, 9.102 real sec
[M::mem_process_seqs] Processed 772368 reads in 202.757 CPU sec, 6.677 real sec
sorting block 36, #reads = 1084816 mem = 536878614 peak = 995180544
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 295766, 32, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 200, 390)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 864)
[M::mem_pestat] mean and std.dev: (229.28, 139.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1101)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 377)
[M::mem_pestat] mean and std.dev: (159.19, 65.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 466)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (116, 244, 688)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1832)
[M::mem_pestat] mean and std.dev: (375.29, 353.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2404)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 340, 973)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2573)
[M::mem_pestat] mean and std.dev: (497.73, 413.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3373)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 770604 sequences (100000297 bp) in 3.408 CPU sec, 4.021 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 295416, 40, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 293, 691)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1777)
[M::mem_pestat] mean and std.dev: (421.22, 368.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2320)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 380)
[M::mem_pestat] mean and std.dev: (159.52, 65.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 470)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (69, 338, 1139)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3279)
[M::mem_pestat] mean and std.dev: (684.77, 860.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4349)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 392, 1000)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2598)
[M::mem_pestat] mean and std.dev: (593.47, 602.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3397)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 770332 sequences (100000249 bp) in 2.761 CPU sec, 2.833 real sec...
[M::mem_process_seqs] Processed 771170 reads in 278.543 CPU sec, 9.063 real sec
sorting block 37, #reads = 1083548 mem = 536881030 peak = 995180544
[M::mem_process_seqs] Processed 770944 reads in 202.669 CPU sec, 6.586 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 294972, 39, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 433, 1310)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3532)
[M::mem_pestat] mean and std.dev: (684.72, 762.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4643)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 380)
[M::mem_pestat] mean and std.dev: (159.66, 65.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 470)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (284, 587, 2376)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6560)
[M::mem_pestat] mean and std.dev: (1464.03, 1745.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8652)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 292, 851)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2135)
[M::mem_pestat] mean and std.dev: (474.65, 396.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2777)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 770620 sequences (100000259 bp) in 3.456 CPU sec, 4.255 real sec...
[M::process] read 769132 sequences (100000007 bp) in 2.500 CPU sec, 2.614 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 295138, 41, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 288, 1106)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3006)
[M::mem_pestat] mean and std.dev: (525.14, 510.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3956)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 380)
[M::mem_pestat] mean and std.dev: (159.79, 66.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 470)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (255, 819, 2115)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5835)
[M::mem_pestat] mean and std.dev: (1186.41, 1323.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7695)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 321, 640)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1594)
[M::mem_pestat] mean and std.dev: (379.69, 285.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2071)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 770604 reads in 278.331 CPU sec, 9.095 real sec
sorting block 38, #reads = 1084769 mem = 536882373 peak = 995180544
[M::mem_process_seqs] Processed 770332 reads in 201.578 CPU sec, 6.634 real sec
sorting block 39, #reads = 1083831 mem = 536881130 peak = 1006137344
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 295891, 28, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 332, 1169)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3181)
[M::mem_pestat] mean and std.dev: (585.90, 728.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4187)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 380)
[M::mem_pestat] mean and std.dev: (159.68, 66.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 470)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (279, 640, 1363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3531)
[M::mem_pestat] mean and std.dev: (679.83, 571.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4615)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 274, 1101)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2945)
[M::mem_pestat] mean and std.dev: (512.67, 554.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3867)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 768908 sequences (100000251 bp) in 3.100 CPU sec, 3.551 real sec...
[M::process] read 768738 sequences (100000044 bp) in 2.582 CPU sec, 2.607 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 295003, 37, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 279, 773)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1987)
[M::mem_pestat] mean and std.dev: (497.23, 446.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2594)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 381)
[M::mem_pestat] mean and std.dev: (160.49, 66.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 471)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (138, 301, 892)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2400)
[M::mem_pestat] mean and std.dev: (494.69, 497.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3154)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 590, 1446)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3910)
[M::mem_pestat] mean and std.dev: (777.03, 720.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5142)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 770620 reads in 275.007 CPU sec, 9.142 real sec
[M::mem_process_seqs] Processed 769132 reads in 198.329 CPU sec, 6.635 real sec
sorting block 40, #reads = 1085916 mem = 536891471 peak = 1006137344
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 293724, 34, 81)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (119, 201, 642)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1688)
[M::mem_pestat] mean and std.dev: (355.10, 348.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2211)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 384)
[M::mem_pestat] mean and std.dev: (160.97, 66.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 475)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 508, 786)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2052)
[M::mem_pestat] mean and std.dev: (405.68, 273.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2685)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 253, 896)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2366)
[M::mem_pestat] mean and std.dev: (440.24, 462.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3101)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 768632 sequences (100000209 bp) in 3.310 CPU sec, 3.741 real sec...
[M::process] read 768170 sequences (100000070 bp) in 2.360 CPU sec, 2.387 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (74, 293892, 30, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (142, 315, 918)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2470)
[M::mem_pestat] mean and std.dev: (447.34, 457.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3246)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 384)
[M::mem_pestat] mean and std.dev: (160.88, 66.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 475)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (101, 772, 1729)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4985)
[M::mem_pestat] mean and std.dev: (1068.52, 1247.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6613)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 533, 1734)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4860)
[M::mem_pestat] mean and std.dev: (980.28, 1068.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6423)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 768908 reads in 277.763 CPU sec, 9.051 real sec
sorting block 41, #reads = 1083344 mem = 536883981 peak = 1006137344
[M::mem_process_seqs] Processed 768738 reads in 210.351 CPU sec, 6.902 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 294210, 32, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 521, 1033)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2733)
[M::mem_pestat] mean and std.dev: (733.02, 686.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3583)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 384)
[M::mem_pestat] mean and std.dev: (161.05, 67.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 475)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 734, 3487)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10161)
[M::mem_pestat] mean and std.dev: (1747.44, 2235.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13498)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 355, 730)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1784)
[M::mem_pestat] mean and std.dev: (513.54, 406.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2311)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 42, #reads = 1081914 mem = 536879610 peak = 1030742016
[M::process] read 767776 sequences (100000150 bp) in 3.412 CPU sec, 3.876 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 294411, 38, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 312, 952)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2506)
[M::mem_pestat] mean and std.dev: (498.13, 506.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3283)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::process] read 767212 sequences (100000063 bp) in 2.636 CPU sec, 2.760 real sec...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 384)
[M::mem_pestat] mean and std.dev: (161.03, 66.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 475)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 617, 1199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3203)
[M::mem_pestat] mean and std.dev: (605.85, 500.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4205)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (241, 417, 1397)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3709)
[M::mem_pestat] mean and std.dev: (625.71, 618.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4865)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 768632 reads in 278.554 CPU sec, 9.069 real sec
[M::mem_process_seqs] Processed 768170 reads in 199.758 CPU sec, 6.568 real sec
sorting block 43, #reads = 1083446 mem = 536880089 peak = 1030742016
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 293696, 39, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 282, 685)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1735)
[M::mem_pestat] mean and std.dev: (394.70, 359.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2260)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 149, 203)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 387)
[M::mem_pestat] mean and std.dev: (161.64, 67.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 479)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 390, 2090)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5956)
[M::mem_pestat] mean and std.dev: (1274.16, 1818.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8546)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 421, 1071)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2845)
[M::mem_pestat] mean and std.dev: (572.39, 474.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3732)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 767130 sequences (100000065 bp) in 3.675 CPU sec, 4.261 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 293005, 38, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 407, 1105)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2965)
[M::mem_pestat] mean and std.dev: (618.75, 575.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3895)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 149, 203)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 387)
[M::mem_pestat] mean and std.dev: (161.73, 67.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 479)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (283, 718, 1042)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2560)
[M::mem_pestat] mean and std.dev: (629.14, 473.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3319)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 319, 627)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1525)
[M::mem_pestat] mean and std.dev: (336.59, 246.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1974)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 767544 sequences (100000008 bp) in 2.374 CPU sec, 2.421 real sec...
[M::mem_process_seqs] Processed 767776 reads in 277.749 CPU sec, 9.071 real sec
sorting block 44, #reads = 1082676 mem = 536889286 peak = 1030742016
[M::mem_process_seqs] Processed 767212 reads in 201.879 CPU sec, 6.656 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (80, 292784, 41, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 397, 2134)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6072)
[M::mem_pestat] mean and std.dev: (657.14, 868.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8041)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 149, 202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 384)
[M::mem_pestat] mean and std.dev: (161.48, 66.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 475)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 466, 1220)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3362)
[M::mem_pestat] mean and std.dev: (664.37, 758.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4433)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 261, 886)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2344)
[M::mem_pestat] mean and std.dev: (485.21, 563.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3073)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 767150 sequences (100000073 bp) in 3.758 CPU sec, 4.417 real sec...
sorting block 45, #reads = 1082215 mem = 536881031 peak = 1030742016
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 293770, 33, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 309, 695)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1761)
[M::mem_pestat] mean and std.dev: (400.33, 343.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2294)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 149, 202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 384)
[M::mem_pestat] mean and std.dev: (161.23, 66.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 475)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (494, 841, 2882)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7658)
[M::mem_pestat] mean and std.dev: (1456.27, 1311.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10046)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 240, 494)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1174)
[M::mem_pestat] mean and std.dev: (329.84, 242.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1514)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 767206 sequences (100000190 bp) in 2.786 CPU sec, 2.811 real sec...
[M::mem_process_seqs] Processed 767130 reads in 282.050 CPU sec, 9.175 real sec
[M::mem_process_seqs] Processed 767544 reads in 204.223 CPU sec, 6.789 real sec
sorting block 46, #reads = 1080139 mem = 536882564 peak = 1030742016
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 293342, 41, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 428, 1233)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3313)
[M::mem_pestat] mean and std.dev: (667.00, 728.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4353)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 149, 202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 384)
[M::mem_pestat] mean and std.dev: (161.51, 66.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 475)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 514, 2877)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8205)
[M::mem_pestat] mean and std.dev: (1267.08, 1734.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10869)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 293, 675)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1635)
[M::mem_pestat] mean and std.dev: (354.74, 315.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2115)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 767128 sequences (100000114 bp) in 3.646 CPU sec, 4.275 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 293113, 52, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (131, 277, 1071)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2951)
[M::mem_pestat] mean and std.dev: (624.51, 713.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3891)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 149, 203)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 387)
[M::mem_pestat] mean and std.dev: (161.63, 66.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 479)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (263, 835, 1695)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4559)
[M::mem_pestat] mean and std.dev: (974.45, 820.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5991)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 319, 784)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1924)
[M::mem_pestat] mean and std.dev: (369.81, 283.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2494)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 767740 sequences (100000077 bp) in 2.405 CPU sec, 2.426 real sec...
[M::mem_process_seqs] Processed 767150 reads in 285.319 CPU sec, 9.615 real sec
[M::mem_process_seqs] Processed 767206 reads in 205.343 CPU sec, 6.770 real sec
sorting block 47, #reads = 1080670 mem = 536887391 peak = 1030742016
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 293465, 28, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 275, 858)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2236)
[M::mem_pestat] mean and std.dev: (462.20, 475.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2925)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 149, 202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 384)
[M::mem_pestat] mean and std.dev: (161.49, 66.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 475)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 608, 1723)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4727)
[M::mem_pestat] mean and std.dev: (713.04, 981.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6229)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 235, 833)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2169)
[M::mem_pestat] mean and std.dev: (466.79, 557.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2837)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 767568 sequences (100000060 bp) in 3.213 CPU sec, 3.781 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 293673, 33, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 388, 877)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2201)
[M::mem_pestat] mean and std.dev: (557.50, 508.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2863)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::process] read 768146 sequences (100000118 bp) in 2.548 CPU sec, 2.571 real sec...
[M::mem_pestat] (25, 50, 75) percentile: (111, 149, 202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 384)
[M::mem_pestat] mean and std.dev: (161.27, 66.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 475)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (139, 504, 865)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2317)
[M::mem_pestat] mean and std.dev: (521.06, 478.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3043)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 335, 847)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2201)
[M::mem_pestat] mean and std.dev: (446.06, 386.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2878)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 767128 reads in 281.121 CPU sec, 9.130 real sec
sorting block 48, #reads = 1079259 mem = 536877969 peak = 1030742016
[M::mem_process_seqs] Processed 767740 reads in 205.076 CPU sec, 6.700 real sec
sorting block 49, #reads = 1080479 mem = 536877640 peak = 1048989696
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 294111, 33, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 409, 1131)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2991)
[M::mem_pestat] mean and std.dev: (549.92, 482.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3921)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 149, 202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 384)
[M::mem_pestat] mean and std.dev: (161.15, 66.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 475)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 691, 1234)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3304)
[M::mem_pestat] mean and std.dev: (683.41, 554.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4339)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 505, 1273)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3411)
[M::mem_pestat] mean and std.dev: (611.68, 627.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4480)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 767948 sequences (100000096 bp) in 3.852 CPU sec, 4.396 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 293850, 25, 75)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 469, 1758)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4866)
[M::mem_pestat] mean and std.dev: (966.17, 1167.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6420)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 381)
[M::mem_pestat] mean and std.dev: (160.59, 66.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 471)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (63, 643, 4070)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12084)
[M::mem_pestat] mean and std.dev: (1637.68, 2068.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 16091)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 309, 727)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1801)
[M::mem_pestat] mean and std.dev: (445.22, 345.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2338)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 771622 sequences (100000281 bp) in 2.690 CPU sec, 2.851 real sec...
[M::mem_process_seqs] Processed 767568 reads in 279.978 CPU sec, 9.121 real sec
[M::mem_process_seqs] Processed 768146 reads in 204.187 CPU sec, 6.698 real sec
sorting block 50, #reads = 1081540 mem = 536877034 peak = 1048989696
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 293729, 34, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 271, 784)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2030)
[M::mem_pestat] mean and std.dev: (305.65, 220.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2653)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 381)
[M::mem_pestat] mean and std.dev: (160.61, 66.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 471)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 410, 869)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2187)
[M::mem_pestat] mean and std.dev: (476.39, 392.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2846)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (242, 507, 1496)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4004)
[M::mem_pestat] mean and std.dev: (738.60, 691.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5258)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 774254 sequences (100000162 bp) in 3.251 CPU sec, 3.774 real sec...
[M::process] read 772914 sequences (100000210 bp) in 2.379 CPU sec, 2.431 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 294749, 26, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 292, 1409)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3873)
[M::mem_pestat] mean and std.dev: (725.06, 818.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5105)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 377)
[M::mem_pestat] mean and std.dev: (158.70, 65.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 466)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (264, 628, 2209)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6099)
[M::mem_pestat] mean and std.dev: (1037.50, 1082.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8044)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 316, 982)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2616)
[M::mem_pestat] mean and std.dev: (486.74, 526.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3433)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 767948 reads in 284.707 CPU sec, 9.253 real sec
sorting block 51, #reads = 1079922 mem = 536880188 peak = 1048989696
[M::mem_process_seqs] Processed 771622 reads in 209.550 CPU sec, 6.834 real sec
sorting block 52, #reads = 1078889 mem = 536882866 peak = 1060057088
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 296264, 35, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 351, 524)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1184)
[M::mem_pestat] mean and std.dev: (344.96, 199.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1514)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 145, 196)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 370)
[M::mem_pestat] mean and std.dev: (157.23, 64.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 457)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (134, 357, 1773)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5051)
[M::mem_pestat] mean and std.dev: (1216.79, 1683.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7950)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 262, 916)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2334)
[M::mem_pestat] mean and std.dev: (427.07, 388.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3043)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 772174 sequences (100000113 bp) in 3.297 CPU sec, 3.897 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 296070, 24, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (145, 203, 688)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1774)
[M::mem_pestat] mean and std.dev: (430.26, 465.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2317)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 146, 198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 376)
[M::mem_pestat] mean and std.dev: (158.09, 64.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 465)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 568, 1476)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3980)
[M::mem_pestat] mean and std.dev: (825.14, 990.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5232)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 291, 647)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1547)
[M::mem_pestat] mean and std.dev: (369.08, 273.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1997)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 770424 sequences (100000209 bp) in 2.549 CPU sec, 2.587 real sec...
[M::mem_process_seqs] Processed 774254 reads in 273.236 CPU sec, 8.871 real sec
[M::mem_process_seqs] Processed 772914 reads in 196.749 CPU sec, 6.397 real sec
sorting block 53, #reads = 1085328 mem = 536886436 peak = 1060057088
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 296065, 27, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 302, 1202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3280)
[M::mem_pestat] mean and std.dev: (562.63, 597.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4319)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 146, 199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 377)
[M::mem_pestat] mean and std.dev: (158.77, 65.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 466)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 511, 2384)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6730)
[M::mem_pestat] mean and std.dev: (1229.00, 1338.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8903)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (139, 208, 475)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1147)
[M::mem_pestat] mean and std.dev: (275.95, 212.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1483)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 770044 sequences (100000109 bp) in 3.743 CPU sec, 4.424 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 295259, 26, 79)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 262, 652)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1632)
[M::mem_pestat] mean and std.dev: (442.08, 404.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2122)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 380)
[M::mem_pestat] mean and std.dev: (159.79, 65.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 470)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (121, 347, 516)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1306)
[M::mem_pestat] mean and std.dev: (335.00, 224.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1701)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 366, 1380)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3760)
[M::mem_pestat] mean and std.dev: (771.69, 778.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4950)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 770738 sequences (100000066 bp) in 2.632 CPU sec, 2.667 real sec...
[M::mem_process_seqs] Processed 772174 reads in 272.356 CPU sec, 8.781 real sec
sorting block 54, #reads = 1088406 mem = 536878772 peak = 1060057088
[M::mem_process_seqs] Processed 770424 reads in 198.605 CPU sec, 6.427 real sec
sorting block 55, #reads = 1087422 mem = 536882233 peak = 1060057088
[M::process] read 770462 sequences (100000027 bp) in 3.386 CPU sec, 3.933 real sec...
[M::process] read 770172 sequences (100000225 bp) in 2.375 CPU sec, 2.436 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 295446, 49, 73)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 335, 907)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2407)
[M::mem_pestat] mean and std.dev: (525.81, 444.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3157)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 380)
[M::mem_pestat] mean and std.dev: (159.67, 66.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 470)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (120, 304, 857)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2331)
[M::mem_pestat] mean and std.dev: (361.07, 387.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3068)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 346, 1134)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2962)
[M::mem_pestat] mean and std.dev: (474.73, 463.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3876)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 770738 reads in 158.971 CPU sec, 5.108 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 294918, 20, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 374, 863)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2213)
[M::mem_pestat] mean and std.dev: (489.05, 433.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2888)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 380)
[M::mem_pestat] mean and std.dev: (159.74, 65.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 470)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (134, 236, 967)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2633)
[M::mem_pestat] mean and std.dev: (401.78, 441.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3466)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 349, 644)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1496)
[M::mem_pestat] mean and std.dev: (426.52, 296.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1922)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 295213, 32, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (239, 468, 1058)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2696)
[M::mem_pestat] mean and std.dev: (602.47, 450.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3515)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 380)
[M::mem_pestat] mean and std.dev: (159.71, 66.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 470)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (116, 427, 1137)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3179)
[M::mem_pestat] mean and std.dev: (615.45, 627.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4200)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 382, 1188)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3212)
[M::mem_pestat] mean and std.dev: (725.80, 749.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4224)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 769652 sequences (100000121 bp) in 2.553 CPU sec, 2.582 real sec...
[M::mem_process_seqs] Processed 770044 reads in 428.383 CPU sec, 13.909 real sec
sorting block 56, #reads = 1085143 mem = 536877377 peak = 1060057088
[M::mem_process_seqs] Processed 770462 reads in 237.093 CPU sec, 7.769 real sec
sorting block 57, #reads = 1084928 mem = 536880556 peak = 1060057088
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 295792, 29, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (133, 373, 1211)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3367)
[M::mem_pestat] mean and std.dev: (575.20, 670.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4445)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 380)
[M::mem_pestat] mean and std.dev: (159.81, 66.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 470)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (115, 256, 1135)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3175)
[M::mem_pestat] mean and std.dev: (497.92, 596.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4195)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 479, 772)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1982)
[M::mem_pestat] mean and std.dev: (507.30, 411.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2587)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 769438 sequences (100000152 bp) in 2.951 CPU sec, 3.622 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 294533, 31, 76)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 281, 619)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1537)
[M::mem_pestat] mean and std.dev: (371.04, 330.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1996)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 380)
[M::mem_pestat] mean and std.dev: (159.92, 66.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 470)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 546, 884)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2232)
[M::mem_pestat] mean and std.dev: (559.79, 465.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2906)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 325, 978)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2508)
[M::mem_pestat] mean and std.dev: (595.94, 610.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3273)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 769768 sequences (100000024 bp) in 2.706 CPU sec, 3.011 real sec...
[M::mem_process_seqs] Processed 770172 reads in 274.121 CPU sec, 9.276 real sec
[M::mem_process_seqs] Processed 769652 reads in 196.040 CPU sec, 6.475 real sec
sorting block 58, #reads = 1084502 mem = 536876621 peak = 1060057088
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 295056, 46, 75)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 253, 557)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1371)
[M::mem_pestat] mean and std.dev: (291.67, 223.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1778)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 148, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 383)
[M::mem_pestat] mean and std.dev: (160.33, 66.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 474)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (257, 720, 1943)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5315)
[M::mem_pestat] mean and std.dev: (1218.72, 1254.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7001)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 376, 659)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1589)
[M::mem_pestat] mean and std.dev: (413.86, 284.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2054)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 768510 sequences (100000071 bp) in 2.887 CPU sec, 3.507 real sec...
[M::process] read 765962 sequences (100000252 bp) in 2.344 CPU sec, 2.366 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 294486, 43, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 265, 510)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1184)
[M::mem_pestat] mean and std.dev: (317.27, 231.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1521)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 383)
[M::mem_pestat] mean and std.dev: (160.09, 66.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 474)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (253, 654, 2559)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7171)
[M::mem_pestat] mean and std.dev: (1188.48, 1196.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9477)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 547, 1374)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3822)
[M::mem_pestat] mean and std.dev: (702.30, 760.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5046)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 769438 reads in 270.853 CPU sec, 8.795 real sec
sorting block 59, #reads = 1084162 mem = 536879853 peak = 1060057088
[M::mem_process_seqs] Processed 769768 reads in 197.499 CPU sec, 6.451 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 294716, 22, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 324, 992)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2678)
[M::mem_pestat] mean and std.dev: (550.98, 611.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3521)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 384)
[M::mem_pestat] mean and std.dev: (160.88, 66.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 475)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (139, 580, 1742)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4948)
[M::mem_pestat] mean and std.dev: (861.45, 1012.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6551)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 517, 900)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2282)
[M::mem_pestat] mean and std.dev: (575.85, 507.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2973)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 60, #reads = 1083890 mem = 536878675 peak = 1060057088
[M::process] read 767610 sequences (100000142 bp) in 3.325 CPU sec, 3.643 real sec...
[M::process] read 767684 sequences (100000286 bp) in 2.466 CPU sec, 2.471 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 293173, 26, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 438, 1095)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2971)
[M::mem_pestat] mean and std.dev: (549.96, 544.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3909)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (112, 150, 204)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 388)
[M::mem_pestat] mean and std.dev: (162.41, 67.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 480)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 728, 1332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3678)
[M::mem_pestat] mean and std.dev: (834.08, 851.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4851)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 284, 729)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1837)
[M::mem_pestat] mean and std.dev: (435.98, 395.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2391)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 768510 reads in 273.833 CPU sec, 8.850 real sec
[M::mem_process_seqs] Processed 765962 reads in 198.270 CPU sec, 6.403 real sec
sorting block 61, #reads = 1082607 mem = 536877719 peak = 1060057088
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 293747, 43, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 419, 788)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2068)
[M::mem_pestat] mean and std.dev: (483.27, 464.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2708)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::process] read 767708 sequences (100000061 bp) in 2.929 CPU sec, 3.455 real sec...
[M::mem_pestat] (25, 50, 75) percentile: (111, 149, 202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 384)
[M::mem_pestat] mean and std.dev: (160.95, 66.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 475)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 456, 885)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2251)
[M::mem_pestat] mean and std.dev: (519.08, 465.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2934)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 448, 1184)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3180)
[M::mem_pestat] mean and std.dev: (608.09, 518.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4178)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 767240 sequences (100000002 bp) in 2.334 CPU sec, 2.353 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 293611, 34, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 369, 794)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1980)
[M::mem_pestat] mean and std.dev: (533.47, 439.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2573)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 384)
[M::mem_pestat] mean and std.dev: (161.11, 66.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 475)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (366, 886, 4986)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 14226)
[M::mem_pestat] mean and std.dev: (2397.56, 2748.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 18846)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 594, 1378)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3754)
[M::mem_pestat] mean and std.dev: (771.10, 714.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4942)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 767610 reads in 276.253 CPU sec, 8.960 real sec
sorting block 62, #reads = 1080936 mem = 536881654 peak = 1060057088
[M::mem_process_seqs] Processed 767684 reads in 201.067 CPU sec, 6.548 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (73, 293583, 30, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 228, 829)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2169)
[M::mem_pestat] mean and std.dev: (399.11, 377.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2839)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 149, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 381)
[M::mem_pestat] mean and std.dev: (160.76, 65.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 471)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 467, 821)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2083)
[M::mem_pestat] mean and std.dev: (527.54, 454.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2714)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 316, 803)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2003)
[M::mem_pestat] mean and std.dev: (462.70, 404.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2603)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 63, #reads = 1081648 mem = 536879172 peak = 1060057088
[M::process] read 767216 sequences (100000214 bp) in 3.255 CPU sec, 3.580 real sec...
[M::process] read 767488 sequences (100000277 bp) in 2.467 CPU sec, 2.471 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 293490, 34, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 494, 1203)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3283)
[M::mem_pestat] mean and std.dev: (637.56, 656.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4323)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 149, 202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 384)
[M::mem_pestat] mean and std.dev: (161.12, 66.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 475)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 838, 1966)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5498)
[M::mem_pestat] mean and std.dev: (1369.06, 1440.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7264)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 355, 983)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2569)
[M::mem_pestat] mean and std.dev: (516.66, 486.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3362)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 767708 reads in 275.102 CPU sec, 8.864 real sec
[M::mem_process_seqs] Processed 767240 reads in 201.169 CPU sec, 6.528 real sec
sorting block 64, #reads = 1081017 mem = 536880596 peak = 1060057088
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 292990, 42, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 248, 636)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1586)
[M::mem_pestat] mean and std.dev: (337.85, 311.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2061)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 149, 202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 384)
[M::mem_pestat] mean and std.dev: (161.23, 66.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 475)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 509, 1363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3651)
[M::mem_pestat] mean and std.dev: (899.17, 909.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4795)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 283, 1011)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2643)
[M::mem_pestat] mean and std.dev: (498.14, 500.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3459)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 767854 sequences (100000125 bp) in 3.249 CPU sec, 3.677 real sec...
[M::process] read 768158 sequences (100000093 bp) in 2.339 CPU sec, 2.400 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 293441, 45, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (226, 379, 999)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2545)
[M::mem_pestat] mean and std.dev: (568.28, 524.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3318)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 149, 202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 384)
[M::mem_pestat] mean and std.dev: (161.20, 66.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 475)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 599, 2068)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5808)
[M::mem_pestat] mean and std.dev: (1024.81, 1269.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7678)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 307, 920)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2404)
[M::mem_pestat] mean and std.dev: (449.86, 463.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3146)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 767216 reads in 276.397 CPU sec, 8.920 real sec
sorting block 65, #reads = 1080271 mem = 536883394 peak = 1060057088
[M::mem_process_seqs] Processed 767488 reads in 200.375 CPU sec, 6.494 real sec
[M::process] read 767954 sequences (100000107 bp) in 3.240 CPU sec, 3.515 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 293856, 34, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 345, 548)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1206)
[M::mem_pestat] mean and std.dev: (371.80, 227.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1535)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 149, 202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 384)
[M::mem_pestat] mean and std.dev: (161.22, 66.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 475)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (135, 587, 1109)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3057)
[M::mem_pestat] mean and std.dev: (655.24, 556.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4031)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 287, 513)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1249)
[M::mem_pestat] mean and std.dev: (318.89, 222.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1617)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 66, #reads = 1080545 mem = 536877219 peak = 1060057088
[M::process] read 766398 sequences (100000130 bp) in 2.546 CPU sec, 2.568 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 294391, 29, 80)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 384, 792)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1946)
[M::mem_pestat] mean and std.dev: (448.18, 335.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2523)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 381)
[M::mem_pestat] mean and std.dev: (160.68, 66.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 471)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (335, 550, 1512)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3866)
[M::mem_pestat] mean and std.dev: (882.75, 869.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5043)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 322, 786)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1974)
[M::mem_pestat] mean and std.dev: (393.21, 367.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2568)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 767854 reads in 274.900 CPU sec, 8.902 real sec
[M::mem_process_seqs] Processed 768158 reads in 198.619 CPU sec, 6.462 real sec
sorting block 67, #reads = 1083199 mem = 536876690 peak = 1060057088
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 293610, 28, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 408, 1054)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2724)
[M::mem_pestat] mean and std.dev: (557.22, 523.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3559)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 381)
[M::mem_pestat] mean and std.dev: (160.56, 65.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 471)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (237, 457, 1862)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5112)
[M::mem_pestat] mean and std.dev: (764.08, 851.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6737)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 396, 1775)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4887)
[M::mem_pestat] mean and std.dev: (841.69, 997.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6443)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 768246 sequences (100000240 bp) in 3.128 CPU sec, 3.740 real sec...
[M::process] read 774138 sequences (100000142 bp) in 2.426 CPU sec, 2.462 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 293028, 45, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 297, 919)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2459)
[M::mem_pestat] mean and std.dev: (492.31, 494.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3229)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 149, 203)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 387)
[M::mem_pestat] mean and std.dev: (161.66, 66.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 479)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (308, 940, 3554)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10046)
[M::mem_pestat] mean and std.dev: (2241.47, 2670.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13292)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 253, 897)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2309)
[M::mem_pestat] mean and std.dev: (427.54, 358.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3015)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 767954 reads in 276.536 CPU sec, 8.934 real sec
[M::mem_process_seqs] Processed 766398 reads in 198.819 CPU sec, 6.439 real sec
sorting block 68, #reads = 1081162 mem = 536881975 peak = 1060057088
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (78, 293538, 24, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 345, 802)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2102)
[M::mem_pestat] mean and std.dev: (452.87, 456.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2752)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 381)
[M::mem_pestat] mean and std.dev: (160.29, 65.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 471)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 658, 1923)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5339)
[M::mem_pestat] mean and std.dev: (1162.17, 1199.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7047)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 307, 584)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1326)
[M::mem_pestat] mean and std.dev: (366.49, 224.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1697)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 779486 sequences (100000195 bp) in 3.468 CPU sec, 3.985 real sec...
[M::process] read 777174 sequences (100000070 bp) in 2.632 CPU sec, 2.669 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 295530, 26, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (225, 475, 872)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2166)
[M::mem_pestat] mean and std.dev: (568.02, 469.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2813)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 145, 195)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 367)
[M::mem_pestat] mean and std.dev: (156.30, 63.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 453)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (130, 434, 965)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2635)
[M::mem_pestat] mean and std.dev: (531.74, 591.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3470)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 253, 1125)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3031)
[M::mem_pestat] mean and std.dev: (429.54, 510.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3984)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 768246 reads in 287.593 CPU sec, 9.293 real sec
sorting block 69, #reads = 1080648 mem = 536875798 peak = 1060057088
[M::mem_process_seqs] Processed 774138 reads in 213.390 CPU sec, 6.898 real sec
sorting block 70, #reads = 1079149 mem = 536880359 peak = 1078915072
[M::process] read 776550 sequences (100000093 bp) in 3.314 CPU sec, 3.731 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 298208, 27, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (133, 188, 1113)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3073)
[M::mem_pestat] mean and std.dev: (514.91, 622.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4053)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (108, 142, 191)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 357)
[M::mem_pestat] mean and std.dev: (153.33, 60.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 440)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (351, 897, 1636)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4206)
[M::mem_pestat] mean and std.dev: (1015.54, 1015.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5491)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (144, 285, 789)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2079)
[M::mem_pestat] mean and std.dev: (363.16, 304.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2724)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 775902 sequences (100000052 bp) in 2.366 CPU sec, 2.431 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 297301, 44, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (142, 317, 989)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2683)
[M::mem_pestat] mean and std.dev: (507.00, 513.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3530)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (108, 143, 193)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 363)
[M::mem_pestat] mean and std.dev: (154.79, 62.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 448)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 468, 1323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3525)
[M::mem_pestat] mean and std.dev: (695.33, 697.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4626)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 281, 855)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2261)
[M::mem_pestat] mean and std.dev: (445.08, 454.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2964)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 779486 reads in 291.016 CPU sec, 9.368 real sec
[M::mem_process_seqs] Processed 777174 reads in 210.512 CPU sec, 6.868 real sec
sorting block 71, #reads = 1083789 mem = 536878335 peak = 1078915072
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 297865, 43, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 249, 657)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1625)
[M::mem_pestat] mean and std.dev: (347.98, 332.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2109)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (108, 144, 194)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 366)
[M::mem_pestat] mean and std.dev: (155.39, 62.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 452)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 487, 1778)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4976)
[M::mem_pestat] mean and std.dev: (963.24, 1073.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6575)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 377, 964)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2558)
[M::mem_pestat] mean and std.dev: (593.15, 559.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3355)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 773388 sequences (100000196 bp) in 3.290 CPU sec, 3.853 real sec...
[M::process] read 773440 sequences (100000149 bp) in 2.538 CPU sec, 2.595 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 297045, 37, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (229, 406, 1562)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4228)
[M::mem_pestat] mean and std.dev: (836.09, 872.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5561)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 144, 194)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 364)
[M::mem_pestat] mean and std.dev: (155.54, 62.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 449)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (290, 622, 1284)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3272)
[M::mem_pestat] mean and std.dev: (690.48, 595.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4266)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 368, 702)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1774)
[M::mem_pestat] mean and std.dev: (429.93, 413.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2310)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 776550 reads in 284.854 CPU sec, 9.185 real sec
sorting block 72, #reads = 1083614 mem = 536884977 peak = 1078915072
[M::mem_process_seqs] Processed 775902 reads in 205.439 CPU sec, 6.669 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 296377, 40, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 335, 775)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1961)
[M::mem_pestat] mean and std.dev: (424.43, 383.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2554)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 146, 196)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 370)
[M::mem_pestat] mean and std.dev: (157.31, 63.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 457)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 428, 1250)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3442)
[M::mem_pestat] mean and std.dev: (628.29, 640.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4538)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 257, 817)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2143)
[M::mem_pestat] mean and std.dev: (422.49, 410.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2806)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 73, #reads = 1084120 mem = 536877187 peak = 1078915072
[M::process] read 772578 sequences (100000039 bp) in 3.288 CPU sec, 3.815 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 296335, 43, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 309, 1292)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3544)
[M::mem_pestat] mean and std.dev: (590.34, 691.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4670)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 146, 196)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 370)
[M::mem_pestat] mean and std.dev: (157.17, 63.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 457)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (259, 615, 1575)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4207)
[M::mem_pestat] mean and std.dev: (786.74, 663.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5523)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 348, 1000)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2604)
[M::mem_pestat] mean and std.dev: (523.74, 496.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3406)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 773222 sequences (100000071 bp) in 2.429 CPU sec, 2.495 real sec...
[M::mem_process_seqs] Processed 773388 reads in 282.865 CPU sec, 9.194 real sec
[M::mem_process_seqs] Processed 773440 reads in 204.741 CPU sec, 6.681 real sec
sorting block 74, #reads = 1084202 mem = 536888114 peak = 1078915072
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 296397, 46, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 355, 770)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1994)
[M::mem_pestat] mean and std.dev: (455.82, 406.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2606)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 146, 197)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 371)
[M::mem_pestat] mean and std.dev: (157.62, 63.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 458)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 692, 1316)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3644)
[M::mem_pestat] mean and std.dev: (779.69, 714.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4808)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 467, 1654)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4640)
[M::mem_pestat] mean and std.dev: (869.92, 1055.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6133)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 772386 sequences (100000146 bp) in 3.379 CPU sec, 3.798 real sec...
[M::process] read 772006 sequences (100000142 bp) in 2.620 CPU sec, 2.713 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 296264, 18, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 374, 1030)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2766)
[M::mem_pestat] mean and std.dev: (585.91, 560.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3634)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 145, 196)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 370)
[M::mem_pestat] mean and std.dev: (157.06, 63.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 457)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 501, 963)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2593)
[M::mem_pestat] mean and std.dev: (666.56, 529.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3408)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 232, 730)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1840)
[M::mem_pestat] mean and std.dev: (429.98, 449.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2395)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 772578 reads in 278.665 CPU sec, 9.047 real sec
sorting block 75, #reads = 1083150 mem = 536881802 peak = 1078915072
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 296348, 29, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (142, 192, 960)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2596)
[M::mem_pestat] mean and std.dev: (488.72, 603.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3414)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 146, 197)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 371)
[M::mem_pestat] mean and std.dev: (157.56, 63.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 458)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (255, 906, 1916)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5238)
[M::mem_pestat] mean and std.dev: (1263.00, 1349.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6899)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 353, 613)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1421)
[M::mem_pestat] mean and std.dev: (348.00, 210.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1825)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 771918 sequences (100000108 bp) in 2.757 CPU sec, 2.764 real sec...
[M::mem_process_seqs] Processed 772386 reads in 169.519 CPU sec, 5.480 real sec
sorting block 76, #reads = 1083388 mem = 536880887 peak = 1078915072
[M::mem_process_seqs] Processed 773222 reads in 420.675 CPU sec, 13.714 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 295686, 45, 73)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 216, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 693)
[M::mem_pestat] mean and std.dev: (198.76, 90.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 875)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 146, 198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 374)
[M::mem_pestat] mean and std.dev: (158.21, 64.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 462)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (131, 477, 1131)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3131)
[M::mem_pestat] mean and std.dev: (580.58, 621.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4131)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 339, 1030)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2718)
[M::mem_pestat] mean and std.dev: (536.26, 473.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3562)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 771918 sequences (100000131 bp) in 3.314 CPU sec, 3.861 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 296061, 30, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 225, 818)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2142)
[M::mem_pestat] mean and std.dev: (369.71, 342.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2804)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 146, 197)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 371)
[M::mem_pestat] mean and std.dev: (157.93, 64.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 458)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (359, 920, 1706)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4400)
[M::mem_pestat] mean and std.dev: (1052.03, 942.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5747)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 519, 1066)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2778)
[M::mem_pestat] mean and std.dev: (689.85, 669.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3634)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 771976 sequences (100000031 bp) in 2.396 CPU sec, 2.527 real sec...
[M::mem_process_seqs] Processed 772006 reads in 345.313 CPU sec, 11.213 real sec
sorting block 77, #reads = 1083025 mem = 536879647 peak = 1078915072
[M::mem_process_seqs] Processed 771918 reads in 210.429 CPU sec, 6.861 real sec
sorting block 78, #reads = 1079085 mem = 536880530 peak = 1078915072
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 296253, 33, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 416, 875)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2205)
[M::mem_pestat] mean and std.dev: (565.18, 472.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2870)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 146, 198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 374)
[M::mem_pestat] mean and std.dev: (157.96, 64.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 462)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 394, 1286)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3546)
[M::mem_pestat] mean and std.dev: (574.87, 554.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4676)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 506, 1448)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3932)
[M::mem_pestat] mean and std.dev: (697.32, 731.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5174)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 770156 sequences (100000074 bp) in 3.234 CPU sec, 3.662 real sec...
[M::process] read 770544 sequences (100000191 bp) in 2.665 CPU sec, 2.678 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 295200, 40, 73)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 279, 715)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1805)
[M::mem_pestat] mean and std.dev: (398.27, 369.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2350)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 146, 197)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 371)
[M::mem_pestat] mean and std.dev: (157.73, 63.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 458)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (287, 545, 885)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2081)
[M::mem_pestat] mean and std.dev: (593.92, 396.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2679)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 280, 832)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2122)
[M::mem_pestat] mean and std.dev: (411.27, 371.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2767)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 771918 reads in 284.124 CPU sec, 9.187 real sec
[M::mem_process_seqs] Processed 771976 reads in 208.077 CPU sec, 6.703 real sec
sorting block 79, #reads = 1082635 mem = 536881971 peak = 1078915072
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 294563, 34, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 321, 700)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1758)
[M::mem_pestat] mean and std.dev: (451.16, 407.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2287)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 374)
[M::mem_pestat] mean and std.dev: (158.71, 64.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 462)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (86, 391, 1168)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3332)
[M::mem_pestat] mean and std.dev: (657.30, 773.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4414)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 484, 1292)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3468)
[M::mem_pestat] mean and std.dev: (632.49, 663.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4556)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 769964 sequences (100000020 bp) in 4.311 CPU sec, 4.496 real sec...
[M::process] read 770460 sequences (100000157 bp) in 2.790 CPU sec, 2.787 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 294511, 44, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 325, 792)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2066)
[M::mem_pestat] mean and std.dev: (416.25, 370.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2703)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 377)
[M::mem_pestat] mean and std.dev: (159.00, 65.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 466)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 580, 1593)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4431)
[M::mem_pestat] mean and std.dev: (690.28, 748.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5850)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 252, 731)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1833)
[M::mem_pestat] mean and std.dev: (435.27, 408.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2384)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 770156 reads in 284.416 CPU sec, 9.036 real sec
sorting block 80, #reads = 1082268 mem = 536883342 peak = 1078915072
[M::mem_process_seqs] Processed 770544 reads in 205.732 CPU sec, 6.558 real sec
sorting block 81, #reads = 1080078 mem = 536886994 peak = 1078915072
[M::process] read 770040 sequences (100000195 bp) in 3.587 CPU sec, 3.885 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 294268, 42, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (144, 207, 472)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1128)
[M::mem_pestat] mean and std.dev: (295.52, 239.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1456)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 377)
[M::mem_pestat] mean and std.dev: (159.05, 64.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 466)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (291, 868, 1442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3744)
[M::mem_pestat] mean and std.dev: (953.48, 849.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4895)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 350, 963)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2473)
[M::mem_pestat] mean and std.dev: (497.27, 437.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3228)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 768830 sequences (100000002 bp) in 2.574 CPU sec, 2.712 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 293857, 47, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 431, 1036)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2752)
[M::mem_pestat] mean and std.dev: (592.39, 594.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3610)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 374)
[M::mem_pestat] mean and std.dev: (158.45, 64.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 462)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 524, 1457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4061)
[M::mem_pestat] mean and std.dev: (724.00, 797.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5363)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 269, 623)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1529)
[M::mem_pestat] mean and std.dev: (361.20, 306.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1982)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 769964 reads in 289.332 CPU sec, 9.268 real sec
[M::mem_process_seqs] Processed 770460 reads in 211.938 CPU sec, 6.833 real sec
sorting block 82, #reads = 1079202 mem = 536880416 peak = 1078915072
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 293983, 31, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 270, 677)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1699)
[M::mem_pestat] mean and std.dev: (411.14, 381.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2210)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 377)
[M::mem_pestat] mean and std.dev: (159.07, 64.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 466)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 570, 1517)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4107)
[M::mem_pestat] mean and std.dev: (762.24, 700.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5402)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 378, 1437)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3927)
[M::mem_pestat] mean and std.dev: (722.10, 890.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5172)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 769318 sequences (100000005 bp) in 3.455 CPU sec, 3.643 real sec...
[M::process] read 768814 sequences (100000145 bp) in 2.740 CPU sec, 2.738 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 293421, 31, 77)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 447, 1829)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5117)
[M::mem_pestat] mean and std.dev: (905.81, 1179.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6761)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 378)
[M::mem_pestat] mean and std.dev: (159.67, 65.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 467)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 581, 1020)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2638)
[M::mem_pestat] mean and std.dev: (573.43, 515.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3447)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 350, 854)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2116)
[M::mem_pestat] mean and std.dev: (448.93, 376.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2747)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 770040 reads in 291.540 CPU sec, 9.294 real sec
sorting block 83, #reads = 1077448 mem = 536879174 peak = 1078915072
[M::mem_process_seqs] Processed 768830 reads in 211.810 CPU sec, 6.761 real sec
sorting block 84, #reads = 1077039 mem = 536878976 peak = 1078915072
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 293744, 35, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 300, 673)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1649)
[M::mem_pestat] mean and std.dev: (393.55, 338.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2137)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 377)
[M::mem_pestat] mean and std.dev: (159.46, 65.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 466)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (247, 639, 1765)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4801)
[M::mem_pestat] mean and std.dev: (991.97, 1040.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6319)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 363, 707)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1727)
[M::mem_pestat] mean and std.dev: (432.23, 320.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2237)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 768546 sequences (100000042 bp) in 3.868 CPU sec, 4.371 real sec...
[M::process] read 778070 sequences (100000056 bp) in 2.678 CPU sec, 2.765 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 292820, 49, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (144, 238, 1024)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2784)
[M::mem_pestat] mean and std.dev: (530.16, 601.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3664)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 375)
[M::mem_pestat] mean and std.dev: (159.34, 64.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 463)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (329, 634, 1700)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4442)
[M::mem_pestat] mean and std.dev: (1016.83, 1002.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5813)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 376, 1064)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2804)
[M::mem_pestat] mean and std.dev: (603.52, 620.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3674)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 769318 reads in 294.439 CPU sec, 9.428 real sec
[M::mem_process_seqs] Processed 768814 reads in 213.555 CPU sec, 6.878 real sec
sorting block 85, #reads = 1078083 mem = 536880277 peak = 1078915072
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 293294, 43, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 341, 1503)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4157)
[M::mem_pestat] mean and std.dev: (572.49, 568.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5484)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 378)
[M::mem_pestat] mean and std.dev: (159.83, 65.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 467)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (569, 993, 3539)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9479)
[M::mem_pestat] mean and std.dev: (1811.81, 2061.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12449)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 234, 769)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1977)
[M::mem_pestat] mean and std.dev: (383.16, 388.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2581)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 782092 sequences (100000227 bp) in 3.061 CPU sec, 3.538 real sec...
[M::process] read 779378 sequences (100000080 bp) in 1.785 CPU sec, 1.799 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 296412, 43, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (122, 218, 671)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1769)
[M::mem_pestat] mean and std.dev: (334.32, 311.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2318)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (108, 143, 192)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 360)
[M::mem_pestat] mean and std.dev: (153.99, 61.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 444)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 613, 1756)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4830)
[M::mem_pestat] mean and std.dev: (1054.41, 1215.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6367)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 353, 986)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2606)
[M::mem_pestat] mean and std.dev: (640.21, 625.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3416)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 768546 reads in 283.678 CPU sec, 9.129 real sec
sorting block 86, #reads = 1077071 mem = 536877451 peak = 1078915072
[M::mem_process_seqs] Processed 778070 reads in 206.566 CPU sec, 6.602 real sec
[M::process] read 778380 sequences (100000097 bp) in 3.138 CPU sec, 3.202 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 298034, 32, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (145, 250, 834)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2212)
[M::mem_pestat] mean and std.dev: (424.37, 449.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2901)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (108, 143, 192)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 360)
[M::mem_pestat] mean and std.dev: (153.75, 61.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 444)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 573, 2208)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6186)
[M::mem_pestat] mean and std.dev: (1036.27, 1200.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8175)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 307, 730)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1890)
[M::mem_pestat] mean and std.dev: (400.98, 391.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2470)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 778084 sequences (100000281 bp) in 2.605 CPU sec, 2.608 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 298709, 37, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (138, 185, 550)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1374)
[M::mem_pestat] mean and std.dev: (275.30, 270.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1786)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (107, 141, 189)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 353)
[M::mem_pestat] mean and std.dev: (152.22, 60.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 435)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (253, 394, 1681)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4537)
[M::mem_pestat] mean and std.dev: (861.56, 894.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5965)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 317, 1033)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2765)
[M::mem_pestat] mean and std.dev: (582.09, 661.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3631)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 779378 reads in 304.912 CPU sec, 9.723 real sec
sorting block 87, #reads = 1072905 mem = 536883785 peak = 1078915072
[M::mem_process_seqs] Processed 782092 reads in 357.037 CPU sec, 11.481 real sec
sorting block 88, #reads = 1077328 mem = 536882515 peak = 1092124672
[M::process] read 777666 sequences (100000144 bp) in 3.401 CPU sec, 3.610 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 297574, 36, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (144, 313, 1165)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3207)
[M::mem_pestat] mean and std.dev: (720.66, 839.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4228)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (108, 143, 192)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 360)
[M::mem_pestat] mean and std.dev: (154.16, 61.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 444)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 483, 1279)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3531)
[M::mem_pestat] mean and std.dev: (674.50, 751.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4657)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 237, 567)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1369)
[M::mem_pestat] mean and std.dev: (358.65, 308.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1770)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 775998 sequences (100000161 bp) in 2.903 CPU sec, 2.903 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 297194, 41, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 348, 829)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2131)
[M::mem_pestat] mean and std.dev: (480.73, 497.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2782)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (108, 143, 193)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 363)
[M::mem_pestat] mean and std.dev: (154.73, 62.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 448)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 494, 1588)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4404)
[M::mem_pestat] mean and std.dev: (707.64, 723.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5812)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 407, 1565)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4313)
[M::mem_pestat] mean and std.dev: (706.04, 798.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5687)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 297212, 30, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (143, 216, 869)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2321)
[M::mem_pestat] mean and std.dev: (472.39, 557.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3047)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (108, 143, 193)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 363)
[M::mem_pestat] mean and std.dev: (154.69, 62.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 448)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (230, 722, 1742)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4766)
[M::mem_pestat] mean and std.dev: (862.58, 834.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6278)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 374, 906)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2356)
[M::mem_pestat] mean and std.dev: (497.74, 414.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3081)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 778380 reads in 430.327 CPU sec, 13.764 real sec
sorting block 89, #reads = 1076067 mem = 536880157 peak = 1092124672
[M::mem_process_seqs] Processed 777666 reads in 348.904 CPU sec, 11.179 real sec
[M::mem_process_seqs] Processed 778084 reads in 396.854 CPU sec, 12.719 real sec
sorting block 90, #reads = 1073199 mem = 536879612 peak = 1092124672
[M::process] read 775154 sequences (100000056 bp) in 4.538 CPU sec, 4.693 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 296953, 30, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (143, 260, 696)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1802)
[M::mem_pestat] mean and std.dev: (400.38, 443.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2355)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 144, 194)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 364)
[M::mem_pestat] mean and std.dev: (155.61, 62.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 449)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (230, 628, 1411)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3773)
[M::mem_pestat] mean and std.dev: (811.66, 748.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4954)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 356, 1046)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2730)
[M::mem_pestat] mean and std.dev: (596.80, 641.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3572)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 774294 sequences (100000269 bp) in 3.109 CPU sec, 3.197 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 296742, 26, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 242, 2809)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8087)
[M::mem_pestat] mean and std.dev: (1465.56, 2266.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10726)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 144, 195)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 367)
[M::mem_pestat] mean and std.dev: (156.14, 63.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 453)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (286, 479, 876)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2056)
[M::mem_pestat] mean and std.dev: (494.43, 329.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2646)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 251, 613)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1487)
[M::mem_pestat] mean and std.dev: (292.79, 232.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1924)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 774584 sequences (100000169 bp) in 2.430 CPU sec, 2.424 real sec...
[M::mem_process_seqs] Processed 775998 reads in 288.824 CPU sec, 9.209 real sec
sorting block 91, #reads = 1077103 mem = 536877778 peak = 1092124672
[M::mem_process_seqs] Processed 775154 reads in 207.474 CPU sec, 6.577 real sec
sorting block 92, #reads = 1079065 mem = 536890239 peak = 1092124672
[M::process] read 773106 sequences (100000050 bp) in 3.069 CPU sec, 3.201 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 296246, 34, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (241, 514, 1549)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4165)
[M::mem_pestat] mean and std.dev: (719.42, 654.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5473)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 145, 195)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 367)
[M::mem_pestat] mean and std.dev: (156.47, 63.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 453)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (279, 541, 971)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2355)
[M::mem_pestat] mean and std.dev: (598.45, 469.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3047)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 265, 647)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1557)
[M::mem_pestat] mean and std.dev: (414.71, 357.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2012)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 772410 sequences (100000125 bp) in 2.460 CPU sec, 2.467 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 296617, 23, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 258, 559)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1355)
[M::mem_pestat] mean and std.dev: (292.42, 207.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1753)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 145, 195)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 367)
[M::mem_pestat] mean and std.dev: (156.52, 63.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 453)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (145, 754, 1386)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3868)
[M::mem_pestat] mean and std.dev: (674.58, 653.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5109)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 306, 696)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1796)
[M::mem_pestat] mean and std.dev: (388.72, 362.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2346)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 774584 reads in 281.403 CPU sec, 8.948 real sec
[M::mem_process_seqs] Processed 774294 reads in 313.620 CPU sec, 10.077 real sec
sorting block 93, #reads = 1076095 mem = 536897942 peak = 1092124672
[M::process] read 774578 sequences (100000026 bp) in 2.528 CPU sec, 2.606 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 296229, 34, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (141, 301, 1119)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3075)
[M::mem_pestat] mean and std.dev: (584.32, 673.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4053)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 146, 197)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 373)
[M::mem_pestat] mean and std.dev: (157.68, 64.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 461)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 612, 847)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2135)
[M::mem_pestat] mean and std.dev: (488.23, 344.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2779)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 405, 1229)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3249)
[M::mem_pestat] mean and std.dev: (642.83, 698.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4259)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 772084 sequences (100000077 bp) in 1.760 CPU sec, 1.765 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 295678, 34, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (140, 265, 707)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1841)
[M::mem_pestat] mean and std.dev: (355.28, 405.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2408)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 146, 197)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 371)
[M::mem_pestat] mean and std.dev: (157.67, 63.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 458)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 411, 992)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2598)
[M::mem_pestat] mean and std.dev: (473.07, 471.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3401)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 314, 843)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2219)
[M::mem_pestat] mean and std.dev: (449.71, 404.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2907)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 773106 reads in 246.663 CPU sec, 7.941 real sec
sorting block 94, #reads = 1080159 mem = 536878426 peak = 1092124672
[M::mem_process_seqs] Processed 772410 reads in 281.354 CPU sec, 9.171 real sec
sorting block 95, #reads = 1078341 mem = 536886057 peak = 1092124672
[M::process] read 771746 sequences (100000184 bp) in 3.056 CPU sec, 3.113 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 295389, 30, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 554, 1587)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4427)
[M::mem_pestat] mean and std.dev: (872.35, 949.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5847)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 146, 197)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 371)
[M::mem_pestat] mean and std.dev: (157.89, 64.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 458)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (145, 408, 646)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1648)
[M::mem_pestat] mean and std.dev: (400.68, 350.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2149)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 343, 752)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1890)
[M::mem_pestat] mean and std.dev: (387.76, 296.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2459)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 771860 sequences (100000187 bp) in 2.310 CPU sec, 2.307 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 296394, 35, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 234, 664)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1684)
[M::mem_pestat] mean and std.dev: (338.35, 354.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2194)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 145, 195)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 367)
[M::mem_pestat] mean and std.dev: (156.30, 63.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 453)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 418, 831)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2157)
[M::mem_pestat] mean and std.dev: (450.84, 422.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2820)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 224, 657)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1653)
[M::mem_pestat] mean and std.dev: (349.65, 318.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2151)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 772084 reads in 247.453 CPU sec, 7.957 real sec
[M::mem_process_seqs] Processed 774578 reads in 282.310 CPU sec, 9.093 real sec
sorting block 96, #reads = 1078714 mem = 536881504 peak = 1092124672
[M::process] read 771028 sequences (100000178 bp) in 2.728 CPU sec, 2.790 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 295038, 34, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 273, 1059)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2883)
[M::mem_pestat] mean and std.dev: (506.98, 513.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3795)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 146, 198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 374)
[M::mem_pestat] mean and std.dev: (158.19, 64.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 462)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (301, 719, 2149)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5845)
[M::mem_pestat] mean and std.dev: (851.79, 1104.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7693)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 313, 1140)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3032)
[M::mem_pestat] mean and std.dev: (569.94, 589.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3978)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 770236 sequences (100000112 bp) in 1.820 CPU sec, 1.824 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 295465, 37, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 302, 884)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2214)
[M::mem_pestat] mean and std.dev: (514.87, 499.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2879)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 146, 197)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 371)
[M::mem_pestat] mean and std.dev: (157.57, 63.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 458)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (135, 347, 815)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2175)
[M::mem_pestat] mean and std.dev: (358.77, 292.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2855)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 536, 1004)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2634)
[M::mem_pestat] mean and std.dev: (616.02, 539.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3449)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 771746 reads in 240.180 CPU sec, 7.640 real sec
sorting block 97, #reads = 1079118 mem = 536879696 peak = 1092124672
[M::mem_process_seqs] Processed 771860 reads in 272.163 CPU sec, 8.677 real sec
[M::process] read 770924 sequences (100000059 bp) in 3.036 CPU sec, 3.074 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 294330, 37, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (248, 553, 901)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2207)
[M::mem_pestat] mean and std.dev: (525.29, 441.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2860)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 374)
[M::mem_pestat] mean and std.dev: (158.33, 64.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 462)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (268, 585, 1832)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4960)
[M::mem_pestat] mean and std.dev: (1081.03, 1184.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6524)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 303, 658)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1584)
[M::mem_pestat] mean and std.dev: (381.76, 295.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2047)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 769458 sequences (100000162 bp) in 2.350 CPU sec, 2.344 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 294791, 43, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 496, 1134)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3084)
[M::mem_pestat] mean and std.dev: (690.98, 671.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4059)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 146, 198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 374)
[M::mem_pestat] mean and std.dev: (158.37, 64.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 462)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (245, 724, 2657)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7481)
[M::mem_pestat] mean and std.dev: (1301.02, 1573.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9893)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 383, 722)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1774)
[M::mem_pestat] mean and std.dev: (413.54, 299.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2300)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 770236 reads in 220.298 CPU sec, 6.972 real sec
sorting block 98, #reads = 1080524 mem = 536885580 peak = 1092124672
[M::mem_process_seqs] Processed 771028 reads in 253.610 CPU sec, 8.062 real sec
sorting block 99, #reads = 1078824 mem = 536883853 peak = 1118126080
[M::process] read 769342 sequences (100000117 bp) in 2.777 CPU sec, 2.875 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 293540, 40, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 261, 687)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1735)
[M::mem_pestat] mean and std.dev: (390.46, 315.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2259)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 147, 199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 375)
[M::mem_pestat] mean and std.dev: (159.06, 64.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 463)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 302, 1181)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3247)
[M::mem_pestat] mean and std.dev: (528.81, 620.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4280)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 492, 1051)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2705)
[M::mem_pestat] mean and std.dev: (634.00, 567.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3532)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 769652 sequences (100000211 bp) in 1.980 CPU sec, 1.986 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 294763, 39, 73)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 219, 572)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1408)
[M::mem_pestat] mean and std.dev: (305.18, 265.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1826)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 374)
[M::mem_pestat] mean and std.dev: (158.34, 64.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 462)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (290, 574, 1911)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5153)
[M::mem_pestat] mean and std.dev: (922.95, 902.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6774)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 621, 1148)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3038)
[M::mem_pestat] mean and std.dev: (706.13, 635.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3983)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 769458 reads in 236.969 CPU sec, 7.531 real sec
sorting block 100, #reads = 1079556 mem = 536884702 peak = 1118126080
[M::mem_process_seqs] Processed 770924 reads in 271.872 CPU sec, 8.678 real sec
[M::process] read 776480 sequences (100000139 bp) in 3.187 CPU sec, 3.228 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 293331, 37, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 343, 913)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2361)
[M::mem_pestat] mean and std.dev: (537.83, 481.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3085)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 377)
[M::mem_pestat] mean and std.dev: (159.18, 64.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 466)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (139, 429, 1133)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3121)
[M::mem_pestat] mean and std.dev: (589.26, 613.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4115)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 352, 708)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1748)
[M::mem_pestat] mean and std.dev: (414.36, 316.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2268)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 776932 sequences (100000081 bp) in 2.380 CPU sec, 2.377 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 293894, 19, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 246, 1505)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4193)
[M::mem_pestat] mean and std.dev: (575.03, 771.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5537)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 377)
[M::mem_pestat] mean and std.dev: (159.14, 64.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 466)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 434, 1446)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4002)
[M::mem_pestat] mean and std.dev: (844.84, 894.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5280)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 493, 1419)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3883)
[M::mem_pestat] mean and std.dev: (620.15, 688.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5115)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 769342 reads in 232.491 CPU sec, 7.365 real sec
sorting block 101, #reads = 1076902 mem = 536881547 peak = 1118126080
[M::mem_process_seqs] Processed 769652 reads in 269.179 CPU sec, 8.561 real sec
sorting block 102, #reads = 1073800 mem = 536879363 peak = 1118126080
[M::process] read 775302 sequences (100000204 bp) in 2.568 CPU sec, 2.708 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 295951, 42, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (235, 559, 1218)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3184)
[M::mem_pestat] mean and std.dev: (706.28, 680.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4167)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (108, 144, 193)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 363)
[M::mem_pestat] mean and std.dev: (154.97, 62.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 448)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (144, 437, 1167)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3213)
[M::mem_pestat] mean and std.dev: (574.97, 595.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4236)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 425, 807)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2079)
[M::mem_pestat] mean and std.dev: (492.76, 455.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2715)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 775266 sequences (100000048 bp) in 1.780 CPU sec, 1.780 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 297032, 37, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 348, 727)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1833)
[M::mem_pestat] mean and std.dev: (430.78, 357.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2386)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (108, 144, 193)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 363)
[M::mem_pestat] mean and std.dev: (154.92, 62.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 448)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (280, 613, 1982)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5386)
[M::mem_pestat] mean and std.dev: (932.06, 1157.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7088)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 529, 1082)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2924)
[M::mem_pestat] mean and std.dev: (646.04, 605.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3845)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 776480 reads in 240.890 CPU sec, 7.675 real sec
sorting block 103, #reads = 1067060 mem = 536879360 peak = 1118126080
[M::mem_process_seqs] Processed 776932 reads in 276.861 CPU sec, 8.847 real sec
[M::process] read 773646 sequences (100000147 bp) in 2.494 CPU sec, 2.541 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 296641, 23, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 312, 914)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2374)
[M::mem_pestat] mean and std.dev: (430.70, 382.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3104)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 145, 195)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 367)
[M::mem_pestat] mean and std.dev: (156.19, 63.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 453)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (310, 568, 1970)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5290)
[M::mem_pestat] mean and std.dev: (923.40, 1020.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6950)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 283, 722)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1828)
[M::mem_pestat] mean and std.dev: (394.71, 326.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2381)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 773110 sequences (100000196 bp) in 1.820 CPU sec, 1.820 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 296016, 41, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (145, 203, 389)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 877)
[M::mem_pestat] mean and std.dev: (210.24, 105.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1121)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 144, 195)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 367)
[M::mem_pestat] mean and std.dev: (156.12, 63.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 453)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (136, 427, 1318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3682)
[M::mem_pestat] mean and std.dev: (602.54, 549.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4864)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 315, 825)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2111)
[M::mem_pestat] mean and std.dev: (458.29, 478.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2754)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 775302 reads in 220.161 CPU sec, 7.009 real sec
sorting block 104, #reads = 1078098 mem = 536879977 peak = 1118126080
[M::process] read 773788 sequences (100000000 bp) in 2.283 CPU sec, 2.289 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 296373, 40, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 318, 834)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2148)
[M::mem_pestat] mean and std.dev: (410.77, 428.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2805)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 145, 196)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 370)
[M::mem_pestat] mean and std.dev: (157.34, 64.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 457)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 722, 2664)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7574)
[M::mem_pestat] mean and std.dev: (1837.90, 2278.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10951)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 241, 1101)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2997)
[M::mem_pestat] mean and std.dev: (552.57, 669.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3945)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 773646 reads in 131.558 CPU sec, 4.594 real sec
sorting block 105, #reads = 1083917 mem = 536889306 peak = 1118126080
[M::mem_process_seqs] Processed 775266 reads in 428.218 CPU sec, 14.093 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 295913, 37, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (234, 444, 1491)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4005)
[M::mem_pestat] mean and std.dev: (803.02, 749.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5262)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 146, 197)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 371)
[M::mem_pestat] mean and std.dev: (157.36, 63.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 458)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 434, 1013)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2653)
[M::mem_pestat] mean and std.dev: (506.38, 446.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3473)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 361, 639)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1531)
[M::mem_pestat] mean and std.dev: (392.74, 302.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1977)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 772780 sequences (100000101 bp) in 2.735 CPU sec, 3.159 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 296254, 49, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 231, 1197)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3281)
[M::mem_pestat] mean and std.dev: (518.45, 640.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4323)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 146, 197)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 373)
[M::mem_pestat] mean and std.dev: (157.49, 64.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 461)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (111, 417, 1224)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3450)
[M::mem_pestat] mean and std.dev: (650.26, 747.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4563)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 274, 1299)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3541)
[M::mem_pestat] mean and std.dev: (596.04, 580.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4662)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 772056 sequences (100000078 bp) in 2.050 CPU sec, 2.052 real sec...
[M::mem_process_seqs] Processed 773110 reads in 242.307 CPU sec, 7.728 real sec
sorting block 106, #reads = 1083743 mem = 536893363 peak = 1118126080
[M::mem_process_seqs] Processed 773788 reads in 161.205 CPU sec, 5.138 real sec
sorting block 107, #reads = 1084689 mem = 536878073 peak = 1118126080
[M::process] read 771900 sequences (100000100 bp) in 2.852 CPU sec, 2.997 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 295956, 42, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 446, 1318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3640)
[M::mem_pestat] mean and std.dev: (761.67, 825.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4801)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 146, 197)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 371)
[M::mem_pestat] mean and std.dev: (157.65, 64.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 458)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 820, 1498)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4096)
[M::mem_pestat] mean and std.dev: (872.22, 918.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5395)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 361, 789)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2073)
[M::mem_pestat] mean and std.dev: (479.50, 410.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2715)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 772268 sequences (100000094 bp) in 1.970 CPU sec, 1.971 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 296000, 32, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 414, 765)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1953)
[M::mem_pestat] mean and std.dev: (486.34, 406.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2547)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 146, 198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 374)
[M::mem_pestat] mean and std.dev: (158.04, 64.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 462)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 1047, 1863)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5199)
[M::mem_pestat] mean and std.dev: (994.63, 1053.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6867)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 553, 1577)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4323)
[M::mem_pestat] mean and std.dev: (873.37, 974.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5696)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 772780 reads in 209.573 CPU sec, 6.659 real sec
[M::mem_process_seqs] Processed 772056 reads in 238.539 CPU sec, 7.612 real sec
sorting block 108, #reads = 1083735 mem = 536877907 peak = 1118126080
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 295491, 50, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (122, 279, 606)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1574)
[M::mem_pestat] mean and std.dev: (371.56, 305.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2058)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 146, 198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 374)
[M::mem_pestat] mean and std.dev: (158.28, 64.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 462)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (139, 403, 1857)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5293)
[M::mem_pestat] mean and std.dev: (778.89, 912.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7011)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 261, 634)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1570)
[M::mem_pestat] mean and std.dev: (367.76, 292.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2038)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 771634 sequences (100000112 bp) in 3.081 CPU sec, 3.239 real sec...
[M::process] read 770722 sequences (100000058 bp) in 2.050 CPU sec, 2.051 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (74, 295650, 26, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (250, 796, 1554)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4162)
[M::mem_pestat] mean and std.dev: (811.22, 872.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5466)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 146, 197)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 371)
[M::mem_pestat] mean and std.dev: (157.77, 64.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 458)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 435, 1292)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3564)
[M::mem_pestat] mean and std.dev: (723.12, 798.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4700)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 293, 1077)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2867)
[M::mem_pestat] mean and std.dev: (557.21, 641.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3762)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 771900 reads in 221.633 CPU sec, 7.099 real sec
sorting block 109, #reads = 1083567 mem = 536876852 peak = 1118126080
[M::mem_process_seqs] Processed 772268 reads in 154.790 CPU sec, 4.949 real sec
sorting block 110, #reads = 1081514 mem = 536879686 peak = 1118126080
[M::process] read 771462 sequences (100000038 bp) in 2.711 CPU sec, 2.812 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 295636, 43, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 417, 641)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1579)
[M::mem_pestat] mean and std.dev: (445.98, 379.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2048)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 377)
[M::mem_pestat] mean and std.dev: (158.78, 64.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 466)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (234, 579, 1518)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4086)
[M::mem_pestat] mean and std.dev: (738.41, 831.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5370)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 326, 540)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1256)
[M::mem_pestat] mean and std.dev: (308.40, 239.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1614)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 770490 sequences (100000076 bp) in 1.966 CPU sec, 1.975 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 295124, 34, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 288, 1198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3280)
[M::mem_pestat] mean and std.dev: (580.70, 606.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4321)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 377)
[M::mem_pestat] mean and std.dev: (159.25, 65.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 466)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (263, 693, 1239)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3191)
[M::mem_pestat] mean and std.dev: (779.45, 613.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4167)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 269, 544)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1330)
[M::mem_pestat] mean and std.dev: (342.71, 295.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1723)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 771634 reads in 215.397 CPU sec, 6.857 real sec
[M::mem_process_seqs] Processed 770722 reads in 149.321 CPU sec, 4.776 real sec
sorting block 111, #reads = 1080544 mem = 536881046 peak = 1118126080
[M::process] read 769968 sequences (100000065 bp) in 2.950 CPU sec, 3.043 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 294236, 36, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (146, 282, 709)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1835)
[M::mem_pestat] mean and std.dev: (430.44, 405.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2398)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 377)
[M::mem_pestat] mean and std.dev: (159.04, 65.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 466)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (288, 559, 1365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3519)
[M::mem_pestat] mean and std.dev: (659.31, 512.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4596)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 463, 978)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2490)
[M::mem_pestat] mean and std.dev: (617.91, 519.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3246)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 770180 sequences (100000260 bp) in 2.060 CPU sec, 2.063 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 295310, 38, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 392, 1230)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3306)
[M::mem_pestat] mean and std.dev: (805.34, 839.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4344)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 146, 198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 374)
[M::mem_pestat] mean and std.dev: (158.37, 64.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 462)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (245, 650, 1775)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4835)
[M::mem_pestat] mean and std.dev: (782.61, 842.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6365)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 319, 734)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1894)
[M::mem_pestat] mean and std.dev: (485.83, 485.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2474)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 770490 reads in 210.939 CPU sec, 6.714 real sec
sorting block 112, #reads = 1082438 mem = 536879587 peak = 1118126080
[M::process] read 769428 sequences (100000159 bp) in 1.816 CPU sec, 1.818 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 294033, 24, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 265, 733)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1873)
[M::mem_pestat] mean and std.dev: (440.70, 387.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2443)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 374)
[M::mem_pestat] mean and std.dev: (158.82, 64.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 462)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (133, 446, 1492)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4210)
[M::mem_pestat] mean and std.dev: (571.91, 651.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5569)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 382, 1239)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3389)
[M::mem_pestat] mean and std.dev: (693.86, 812.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4464)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 769968 reads in 125.432 CPU sec, 4.251 real sec
sorting block 113, #reads = 1078907 mem = 536878371 peak = 1118126080
[M::mem_process_seqs] Processed 771462 reads in 406.754 CPU sec, 13.261 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 294248, 35, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (127, 211, 684)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1798)
[M::mem_pestat] mean and std.dev: (304.25, 269.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2355)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 377)
[M::mem_pestat] mean and std.dev: (158.90, 64.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 466)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 604, 1651)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4649)
[M::mem_pestat] mean and std.dev: (897.03, 935.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6148)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 318, 914)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2334)
[M::mem_pestat] mean and std.dev: (561.26, 568.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3044)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 769568 sequences (100000056 bp) in 2.759 CPU sec, 3.237 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 293367, 44, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 277, 765)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1955)
[M::mem_pestat] mean and std.dev: (396.58, 349.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2550)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 147, 199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 375)
[M::mem_pestat] mean and std.dev: (159.26, 64.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 463)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (117, 301, 1302)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3672)
[M::mem_pestat] mean and std.dev: (569.87, 751.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4857)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 410, 1011)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2645)
[M::mem_pestat] mean and std.dev: (565.21, 542.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3462)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 769670 sequences (100000126 bp) in 1.830 CPU sec, 1.834 real sec...
[M::mem_process_seqs] Processed 770180 reads in 337.641 CPU sec, 10.750 real sec
sorting block 114, #reads = 1082436 mem = 536880928 peak = 1118126080
[M::mem_process_seqs] Processed 769428 reads in 171.540 CPU sec, 5.492 real sec
sorting block 115, #reads = 1076918 mem = 536877366 peak = 1118126080
[M::process] read 770458 sequences (100000184 bp) in 2.382 CPU sec, 2.991 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 293492, 26, 72)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 354, 1125)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3071)
[M::mem_pestat] mean and std.dev: (576.88, 561.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4044)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 377)
[M::mem_pestat] mean and std.dev: (159.14, 64.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 466)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (269, 426, 1131)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2855)
[M::mem_pestat] mean and std.dev: (564.29, 482.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3717)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 278, 744)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1900)
[M::mem_pestat] mean and std.dev: (409.40, 404.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2478)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 769300 sequences (100000172 bp) in 1.960 CPU sec, 1.958 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 293544, 34, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 338, 979)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2567)
[M::mem_pestat] mean and std.dev: (471.32, 410.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3361)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 147, 199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 375)
[M::mem_pestat] mean and std.dev: (159.20, 64.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 463)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (283, 643, 1290)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3304)
[M::mem_pestat] mean and std.dev: (722.13, 579.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4311)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 420, 1051)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2709)
[M::mem_pestat] mean and std.dev: (502.67, 478.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3538)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 769670 reads in 216.937 CPU sec, 6.912 real sec
sorting block 116, #reads = 1076458 mem = 536876585 peak = 1118126080
[M::mem_process_seqs] Processed 769568 reads in 255.626 CPU sec, 8.181 real sec
[M::process] read 769168 sequences (100000109 bp) in 2.617 CPU sec, 2.665 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 294059, 48, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 313, 955)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2515)
[M::mem_pestat] mean and std.dev: (518.41, 513.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3295)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 374)
[M::mem_pestat] mean and std.dev: (158.56, 64.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 462)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (135, 676, 1099)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3027)
[M::mem_pestat] mean and std.dev: (646.10, 704.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3991)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 316, 835)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2169)
[M::mem_pestat] mean and std.dev: (478.17, 458.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2836)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 777710 sequences (100000183 bp) in 1.840 CPU sec, 1.848 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 293419, 46, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 276, 912)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2440)
[M::mem_pestat] mean and std.dev: (471.22, 502.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3204)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 147, 199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 375)
[M::mem_pestat] mean and std.dev: (159.39, 64.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 463)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 394, 1175)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3087)
[M::mem_pestat] mean and std.dev: (652.55, 597.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4043)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (250, 529, 1467)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3901)
[M::mem_pestat] mean and std.dev: (911.03, 888.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5118)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 770458 reads in 219.093 CPU sec, 6.972 real sec
sorting block 117, #reads = 1077761 mem = 536878008 peak = 1118126080
[M::mem_process_seqs] Processed 769300 reads in 252.426 CPU sec, 8.068 real sec
sorting block 118, #reads = 1074706 mem = 536886230 peak = 1118126080
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 293582, 46, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 446, 1088)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2922)
[M::mem_pestat] mean and std.dev: (470.88, 390.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3839)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 147, 199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 375)
[M::mem_pestat] mean and std.dev: (159.30, 64.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 463)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 599, 1318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3622)
[M::mem_pestat] mean and std.dev: (731.41, 792.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4774)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 276, 1336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3672)
[M::mem_pestat] mean and std.dev: (595.71, 789.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4840)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 782698 sequences (100000283 bp) in 2.925 CPU sec, 3.055 real sec...
[M::process] read 780110 sequences (100000191 bp) in 1.800 CPU sec, 1.808 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 295168, 39, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 282, 1018)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2732)
[M::mem_pestat] mean and std.dev: (546.68, 614.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3589)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (108, 143, 192)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 360)
[M::mem_pestat] mean and std.dev: (154.08, 61.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 444)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 275, 793)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2061)
[M::mem_pestat] mean and std.dev: (444.35, 523.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2695)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 532, 1081)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2809)
[M::mem_pestat] mean and std.dev: (693.86, 622.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3673)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 769168 reads in 241.249 CPU sec, 7.691 real sec
[M::mem_process_seqs] Processed 777710 reads in 182.730 CPU sec, 5.842 real sec
sorting block 119, #reads = 1070562 mem = 536881910 peak = 1118126080
[M::process] read 778232 sequences (100000267 bp) in 2.743 CPU sec, 2.789 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 298353, 30, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 277, 700)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1806)
[M::mem_pestat] mean and std.dev: (389.61, 373.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2359)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (107, 141, 189)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 353)
[M::mem_pestat] mean and std.dev: (151.80, 60.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 435)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 616, 1447)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3919)
[M::mem_pestat] mean and std.dev: (792.86, 714.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5155)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 368, 651)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1557)
[M::mem_pestat] mean and std.dev: (370.19, 243.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2010)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 776330 sequences (100000150 bp) in 1.820 CPU sec, 1.816 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 297226, 36, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 258, 855)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2243)
[M::mem_pestat] mean and std.dev: (442.00, 456.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2937)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (108, 142, 191)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 357)
[M::mem_pestat] mean and std.dev: (153.13, 60.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 440)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (328, 663, 1838)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4858)
[M::mem_pestat] mean and std.dev: (1005.53, 933.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6368)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 456, 1196)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3210)
[M::mem_pestat] mean and std.dev: (643.85, 626.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4217)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 782698 reads in 233.710 CPU sec, 7.441 real sec
sorting block 120, #reads = 1064448 mem = 536881553 peak = 1118126080
[M::mem_process_seqs] Processed 780110 reads in 268.937 CPU sec, 8.590 real sec
sorting block 121, #reads = 1076708 mem = 536877517 peak = 1118126080
[M::process] read 776880 sequences (100000169 bp) in 2.728 CPU sec, 2.783 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 296933, 34, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (142, 342, 1255)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3481)
[M::mem_pestat] mean and std.dev: (484.34, 510.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4594)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 144, 194)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 364)
[M::mem_pestat] mean and std.dev: (155.50, 62.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 449)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 525, 1198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3204)
[M::mem_pestat] mean and std.dev: (696.61, 639.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4207)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 451, 992)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2562)
[M::mem_pestat] mean and std.dev: (596.52, 553.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3347)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 775980 sequences (100000038 bp) in 1.830 CPU sec, 1.830 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 296679, 34, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 299, 1558)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4288)
[M::mem_pestat] mean and std.dev: (731.02, 894.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5653)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (108, 143, 192)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 360)
[M::mem_pestat] mean and std.dev: (154.03, 61.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 444)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 664, 1478)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3972)
[M::mem_pestat] mean and std.dev: (821.83, 819.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5219)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 393, 1105)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2945)
[M::mem_pestat] mean and std.dev: (656.61, 692.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3865)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 776330 reads in 226.800 CPU sec, 7.223 real sec
[M::process] read 775422 sequences (100000109 bp) in 2.288 CPU sec, 2.294 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 296636, 50, 78)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 522, 1678)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4652)
[M::mem_pestat] mean and std.dev: (961.39, 1242.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6139)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 144, 194)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 364)
[M::mem_pestat] mean and std.dev: (155.41, 62.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 449)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 620, 1965)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5583)
[M::mem_pestat] mean and std.dev: (1221.33, 1545.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7404)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 245, 594)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1482)
[M::mem_pestat] mean and std.dev: (364.52, 318.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1926)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 775980 reads in 135.136 CPU sec, 4.310 real sec
sorting block 122, #reads = 1076765 mem = 536877044 peak = 1118126080
[M::mem_process_seqs] Processed 778232 reads in 422.595 CPU sec, 13.501 real sec
sorting block 123, #reads = 1076407 mem = 536878322 peak = 1137537024
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 296879, 34, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 484, 1155)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3075)
[M::mem_pestat] mean and std.dev: (553.59, 503.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4035)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (108, 144, 194)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 366)
[M::mem_pestat] mean and std.dev: (155.33, 62.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 452)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 408, 1136)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3110)
[M::mem_pestat] mean and std.dev: (692.03, 700.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4097)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 253, 1511)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4211)
[M::mem_pestat] mean and std.dev: (611.07, 779.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5561)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 773446 sequences (100000234 bp) in 2.320 CPU sec, 2.413 real sec...
[M::process] read 773662 sequences (100000115 bp) in 1.770 CPU sec, 1.763 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 296477, 35, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (129, 215, 802)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2148)
[M::mem_pestat] mean and std.dev: (407.29, 475.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2821)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 144, 194)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 364)
[M::mem_pestat] mean and std.dev: (155.44, 62.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 449)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (297, 895, 1934)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5208)
[M::mem_pestat] mean and std.dev: (1012.65, 1040.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6845)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 489, 1462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3964)
[M::mem_pestat] mean and std.dev: (629.73, 559.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5215)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 776880 reads in 352.775 CPU sec, 11.230 real sec
sorting block 124, #reads = 1075588 mem = 536884444 peak = 1137537024
[M::mem_process_seqs] Processed 775422 reads in 158.164 CPU sec, 5.061 real sec
[M::process] read 773156 sequences (100000150 bp) in 2.379 CPU sec, 2.419 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 295250, 41, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 543, 1358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3742)
[M::mem_pestat] mean and std.dev: (931.36, 1037.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5080)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 145, 196)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 370)
[M::mem_pestat] mean and std.dev: (156.83, 63.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 457)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (143, 616, 1457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4085)
[M::mem_pestat] mean and std.dev: (803.77, 742.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5399)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 226, 1081)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2917)
[M::mem_pestat] mean and std.dev: (572.96, 729.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3835)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 770780 sequences (100000040 bp) in 1.770 CPU sec, 1.777 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 295464, 34, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (142, 219, 1354)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3778)
[M::mem_pestat] mean and std.dev: (834.37, 1077.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5143)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 145, 195)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 367)
[M::mem_pestat] mean and std.dev: (156.67, 63.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 453)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 503, 1144)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3056)
[M::mem_pestat] mean and std.dev: (602.16, 637.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4012)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 291, 1050)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2754)
[M::mem_pestat] mean and std.dev: (520.02, 522.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3606)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 773446 reads in 213.248 CPU sec, 6.782 real sec
sorting block 125, #reads = 1078635 mem = 536889529 peak = 1137537024
[M::mem_process_seqs] Processed 773662 reads in 245.984 CPU sec, 7.851 real sec
sorting block 126, #reads = 1078691 mem = 536885904 peak = 1137537024
[M::process] read 770858 sequences (100000287 bp) in 2.249 CPU sec, 2.285 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (79, 295172, 42, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 282, 775)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1947)
[M::mem_pestat] mean and std.dev: (449.57, 394.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2533)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (109, 146, 196)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 370)
[M::mem_pestat] mean and std.dev: (157.16, 63.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 457)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (286, 529, 1366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3526)
[M::mem_pestat] mean and std.dev: (634.40, 660.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4606)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 312, 1210)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3244)
[M::mem_pestat] mean and std.dev: (696.50, 775.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4261)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 771070 sequences (100000289 bp) in 1.760 CPU sec, 1.758 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 294026, 49, 79)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 343, 1368)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3792)
[M::mem_pestat] mean and std.dev: (629.67, 745.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5004)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 377)
[M::mem_pestat] mean and std.dev: (158.82, 64.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 466)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (244, 815, 1880)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5152)
[M::mem_pestat] mean and std.dev: (1151.40, 1195.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6788)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 281, 691)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1751)
[M::mem_pestat] mean and std.dev: (374.59, 333.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2281)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 294604, 41, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 712, 1355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3721)
[M::mem_pestat] mean and std.dev: (867.07, 794.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4904)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 374)
[M::mem_pestat] mean and std.dev: (158.45, 64.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 462)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 658, 2080)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5820)
[M::mem_pestat] mean and std.dev: (751.37, 876.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7690)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 293, 1228)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3336)
[M::mem_pestat] mean and std.dev: (591.98, 651.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4390)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 773156 reads in 301.609 CPU sec, 9.633 real sec
sorting block 127, #reads = 1075634 mem = 536878749 peak = 1137537024
[M::mem_process_seqs] Processed 770780 reads in 240.075 CPU sec, 7.714 real sec
[M::mem_process_seqs] Processed 770858 reads in 272.634 CPU sec, 8.757 real sec
[M::process] read 770720 sequences (100000106 bp) in 2.643 CPU sec, 2.731 real sec...
sorting block 128, #reads = 1077061 mem = 536876788 peak = 1137537024
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 294515, 33, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 513, 1056)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2808)
[M::mem_pestat] mean and std.dev: (640.80, 577.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3684)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 146, 198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 374)
[M::mem_pestat] mean and std.dev: (158.28, 64.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 462)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 438, 2101)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5911)
[M::mem_pestat] mean and std.dev: (772.43, 933.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7816)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 305, 1101)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2911)
[M::mem_pestat] mean and std.dev: (517.79, 536.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3816)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 770070 sequences (100000001 bp) in 2.118 CPU sec, 2.185 real sec...
[M::process] read 770416 sequences (100000234 bp) in 1.700 CPU sec, 1.691 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 294485, 42, 73)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 260, 839)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2209)
[M::mem_pestat] mean and std.dev: (440.16, 473.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2894)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 374)
[M::mem_pestat] mean and std.dev: (158.52, 64.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 462)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 450, 1220)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3276)
[M::mem_pestat] mean and std.dev: (717.97, 724.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4304)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 393, 1279)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3497)
[M::mem_pestat] mean and std.dev: (673.60, 711.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4606)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 771070 reads in 216.809 CPU sec, 6.919 real sec
sorting block 129, #reads = 1075879 mem = 536886167 peak = 1137537024
[M::mem_process_seqs] Processed 770720 reads in 151.242 CPU sec, 4.821 real sec
[M::process] read 770174 sequences (100000075 bp) in 2.435 CPU sec, 2.516 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 293778, 37, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 236, 871)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2277)
[M::mem_pestat] mean and std.dev: (434.39, 404.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2980)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 377)
[M::mem_pestat] mean and std.dev: (159.07, 64.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 466)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 509, 1164)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3150)
[M::mem_pestat] mean and std.dev: (733.00, 719.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4143)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 329, 918)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2410)
[M::mem_pestat] mean and std.dev: (533.22, 530.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3156)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 769956 sequences (100000212 bp) in 1.740 CPU sec, 1.744 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 293961, 38, 76)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 255, 824)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2146)
[M::mem_pestat] mean and std.dev: (433.79, 457.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2807)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 377)
[M::mem_pestat] mean and std.dev: (159.11, 64.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 466)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (377, 836, 1443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3575)
[M::mem_pestat] mean and std.dev: (909.85, 815.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4641)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 382, 926)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2404)
[M::mem_pestat] mean and std.dev: (577.41, 557.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3143)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 770070 reads in 206.625 CPU sec, 6.568 real sec
sorting block 130, #reads = 1077477 mem = 536886379 peak = 1137537024
[M::mem_process_seqs] Processed 770416 reads in 237.343 CPU sec, 7.623 real sec
sorting block 131, #reads = 1078581 mem = 536879127 peak = 1137537024
[M::process] read 770282 sequences (100000266 bp) in 2.184 CPU sec, 2.234 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 294268, 31, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 314, 1041)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2781)
[M::mem_pestat] mean and std.dev: (527.98, 657.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3651)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 374)
[M::mem_pestat] mean and std.dev: (158.63, 64.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 462)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (89, 288, 1419)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4079)
[M::mem_pestat] mean and std.dev: (757.07, 877.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5409)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 333, 1204)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3202)
[M::mem_pestat] mean and std.dev: (582.04, 615.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4201)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 769166 sequences (100000014 bp) in 1.730 CPU sec, 1.736 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 293879, 46, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 357, 914)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2418)
[M::mem_pestat] mean and std.dev: (490.85, 438.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3170)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 377)
[M::mem_pestat] mean and std.dev: (158.98, 64.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 466)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 810, 1481)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4077)
[M::mem_pestat] mean and std.dev: (826.43, 867.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5375)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 430, 1178)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3154)
[M::mem_pestat] mean and std.dev: (601.48, 571.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4142)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 770174 reads in 209.784 CPU sec, 6.727 real sec
sorting block 132, #reads = 1078398 mem = 536889408 peak = 1137537024
[M::mem_process_seqs] Processed 769956 reads in 238.397 CPU sec, 7.617 real sec
[M::process] read 768818 sequences (100000150 bp) in 2.400 CPU sec, 2.446 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 293505, 30, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 409, 792)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2010)
[M::mem_pestat] mean and std.dev: (475.98, 387.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2619)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 378)
[M::mem_pestat] mean and std.dev: (159.77, 65.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 467)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (124, 288, 698)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1846)
[M::mem_pestat] mean and std.dev: (368.44, 325.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2420)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 299, 759)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1911)
[M::mem_pestat] mean and std.dev: (391.63, 373.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2487)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 630386 sequences (81871845 bp) in 1.500 CPU sec, 1.500 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 294328, 53, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (138, 303, 1357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3795)
[M::mem_pestat] mean and std.dev: (661.92, 894.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5014)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 377)
[M::mem_pestat] mean and std.dev: (158.86, 64.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 466)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 603, 1308)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3534)
[M::mem_pestat] mean and std.dev: (889.96, 896.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4647)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 375, 927)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2405)
[M::mem_pestat] mean and std.dev: (509.22, 428.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3144)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 769166 reads in 216.519 CPU sec, 6.899 real sec
sorting block 133, #reads = 1074634 mem = 536878983 peak = 1137537024
[M::mem_process_seqs] Processed 770282 reads in 255.425 CPU sec, 8.165 real sec
sorting block 134, #reads = 1078472 mem = 536882275 peak = 1137537024
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 240429, 37, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 257, 844)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2176)
[M::mem_pestat] mean and std.dev: (430.66, 425.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2842)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (110, 147, 199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 377)
[M::mem_pestat] mean and std.dev: (159.27, 65.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 466)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (390, 1317, 1786)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4578)
[M::mem_pestat] mean and std.dev: (1132.91, 919.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5974)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 452, 1332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3652)
[M::mem_pestat] mean and std.dev: (668.43, 732.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4812)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (73, 293511, 28, 72)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 217, 857)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2243)
[M::mem_pestat] mean and std.dev: (466.89, 482.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2936)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (111, 148, 200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 378)
[M::mem_pestat] mean and std.dev: (159.60, 65.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 467)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 642, 854)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2130)
[M::mem_pestat] mean and std.dev: (629.78, 526.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2768)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 380, 1330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3606)
[M::mem_pestat] mean and std.dev: (638.27, 664.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4744)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 630386 reads in 188.106 CPU sec, 6.077 real sec
[M::mem_process_seqs] Processed 768818 reads in 217.864 CPU sec, 7.049 real sec
sorting block 135, #reads = 1074077 mem = 536879088 peak = 1137537024
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000c06f2
  features: 1f8bfbff fffab20b
  extended: f1bf07ab 1a407f7e
  amd bits: 2c100800 00000121
     brand: Intel(R) Xeon(R) Platinum 8559C
threads: 31
algo: bwa-mem
license: sentieon:klib=31
reads: 145603560
overall: 72317456384 mem 30278.864 user 483.699 sys 1019.993 real
[main] Version: 0.7.17-r1188
[main] CMD: /opt/conda/share/sentieon-202308.03-3/libexec/bwa mem -K 100000000 -Y -R @RG\tID:A23MHWWLT4.1136_81F-T1-TDNA-1_A23MHWWLT4_1.L007\tPU:L007\tSM:1136_81F-T1-TDNA-1_A23MHWWLT4_1\tLB:1136_81F-T1-TDNA-1_A23MHWWLT4_1\tDS:s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta\tPL:ILLUMINA -t 31 ./BWAIndex/Homo_sapiens_assembly38.fasta.64 1136_81F-T1-TDNA-1_A23MHWWLT4_1_R1.fastq.gz 1136_81F-T1-TDNA-1_A23MHWWLT4_1_R2.fastq.gz
[main] Real time: 1020.028 sec; CPU: 30762.566 sec
sorting block 136, #reads = 640524 mem = 319637447 peak = 1137537024
uniq header count 1
merging 137 blocks
sw version: sentieon-genomics-202308.03
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000c06f2
  features: 1f8bfbff fffab20b
  extended: f1bf07ab 1a407f7e
  amd bits: 2c100800 00000121
     brand: Intel(R) Xeon(R) Platinum 8559C
threads: 31 max 192
algo: util-sort
license: sentieon:util=1
output file size: 8860222405
output reads: 147627464
bam_mem_sort: 137 calls 84.233 user 2.753 sys 89.417 real
bam_write: 137 calls 76.464 user 5.539 sys 161.740 real
execute: 1 calls 29.383 user 1.394 sys 1071.827 real
merge_files: 1 calls 29.354 user 1.364 sys 51.491 real
parse_chunk: 2186 calls 123.083 user 33.308 sys 193.391 real
read_chunk: 5971 calls 69.786 user 36.839 sys 956.972 real
sort_block: 1 calls 52.459 user 36.234 sys 934.058 real
write_chunk: 3783 calls 29.005 user 0.995 sys 50.459 real
overall: 4516933632 mem 2124.862 user 97.632 sys 1071.847 real
ls: cannot access '*.cram': No such file or directory