This software is licensed to bgold@natera.com by Sentieon Inc.
cmdline: /opt/conda/share/sentieon-202308.03-3/libexec/util sort -r Homo_sapiens_assembly38.fasta -t 31 -o 1136_8DV-T1-TDNA-1_A23MHWWLT4_1.bam --sam2bam -
This software is licensed to bgold@natera.com by Sentieon Inc.
version: sentieon-genomics-202308.03
[M::bwa_idx_load_from_disk] read 3171 ALT contigs
[M::main_mem] bwa index loaded in 1570.079 CPU sec, 60.825 real sec
[M::process] read 724474 sequences (100000248 bp) in 1.159 CPU sec, 1.164 real sec...
[M::process] read 723020 sequences (100000121 bp) in 1.438 CPU sec, 1.461 real sec...
[M::process] read 721826 sequences (100000010 bp) in 1.495 CPU sec, 1.523 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 291060, 17, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 200, 432)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1000)
[M::mem_pestat] mean and std.dev: (243.07, 148.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1284)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 189, 285)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 591)
[M::mem_pestat] mean and std.dev: (216.75, 111.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 744)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (570, 652, 2569)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6567)
[M::mem_pestat] mean and std.dev: (864.50, 717.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8566)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 328, 601)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1411)
[M::mem_pestat] mean and std.dev: (414.20, 305.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1816)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 721138 sequences (100000117 bp) in 1.391 CPU sec, 1.404 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 291103, 11, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (304, 446, 1116)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2740)
[M::mem_pestat] mean and std.dev: (818.25, 737.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3769)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 192, 291)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 605)
[M::mem_pestat] mean and std.dev: (220.84, 115.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 762)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (236, 309, 2860)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8108)
[M::mem_pestat] mean and std.dev: (1282.27, 1551.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10732)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 320, 383)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 803)
[M::mem_pestat] mean and std.dev: (281.70, 111.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1013)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 290491, 19, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 395, 1185)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3161)
[M::mem_pestat] mean and std.dev: (653.26, 652.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4149)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 193, 293)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 611)
[M::mem_pestat] mean and std.dev: (222.76, 116.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 770)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (123, 468, 1113)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3093)
[M::mem_pestat] mean and std.dev: (585.26, 476.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4083)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 365, 809)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2013)
[M::mem_pestat] mean and std.dev: (446.94, 394.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2615)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 724474 reads in 277.427 CPU sec, 8.862 real sec
[M::mem_process_seqs] Processed 723020 reads in 205.783 CPU sec, 6.603 real sec
sorting block 0, #reads = 1091904 mem = 536876409 peak = 613597184
[M::mem_process_seqs] Processed 721826 reads in 231.376 CPU sec, 7.419 real sec
[M::process] read 720854 sequences (100000028 bp) in 2.255 CPU sec, 2.352 real sec...
sorting block 1, #reads = 1092622 mem = 536883559 peak = 832225280
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 290927, 17, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 270, 664)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1570)
[M::mem_pestat] mean and std.dev: (337.29, 237.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2023)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 195, 296)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 618)
[M::mem_pestat] mean and std.dev: (224.46, 117.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 779)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (251, 808, 842)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2024)
[M::mem_pestat] mean and std.dev: (489.21, 325.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2615)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 412, 1735)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4815)
[M::mem_pestat] mean and std.dev: (939.24, 1149.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6355)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720234 sequences (100000082 bp) in 2.070 CPU sec, 2.077 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 291058, 20, 23)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 288, 548)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1248)
[M::mem_pestat] mean and std.dev: (331.58, 212.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1598)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 195, 298)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 624)
[M::mem_pestat] mean and std.dev: (225.71, 119.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 787)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (433, 836, 1760)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4414)
[M::mem_pestat] mean and std.dev: (1098.79, 888.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5741)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 268, 443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1001)
[M::mem_pestat] mean and std.dev: (256.05, 104.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1280)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 719648 sequences (100000226 bp) in 1.860 CPU sec, 1.862 real sec...
[M::mem_process_seqs] Processed 721138 reads in 179.523 CPU sec, 5.656 real sec
[M::mem_process_seqs] Processed 720854 reads in 126.996 CPU sec, 4.015 real sec
sorting block 2, #reads = 1092817 mem = 536879115 peak = 832225280
[M::process] read 718944 sequences (100000205 bp) in 2.493 CPU sec, 2.531 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 290169, 12, 22)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 554, 969)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2523)
[M::mem_pestat] mean and std.dev: (545.65, 417.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3300)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 197, 301)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 631)
[M::mem_pestat] mean and std.dev: (227.63, 120.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 796)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (302, 712, 1004)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2408)
[M::mem_pestat] mean and std.dev: (735.08, 632.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3264)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 195, 457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1075)
[M::mem_pestat] mean and std.dev: (262.00, 204.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1384)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 718662 sequences (100000227 bp) in 2.005 CPU sec, 2.014 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 289923, 16, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 266, 785)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1989)
[M::mem_pestat] mean and std.dev: (337.44, 228.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2591)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 197, 301)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 631)
[M::mem_pestat] mean and std.dev: (227.98, 120.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 796)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (327, 1301, 1773)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4665)
[M::mem_pestat] mean and std.dev: (1026.87, 828.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6111)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 313, 965)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2535)
[M::mem_pestat] mean and std.dev: (405.68, 433.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3320)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 720234 reads in 179.416 CPU sec, 5.667 real sec
[M::mem_process_seqs] Processed 719648 reads in 205.249 CPU sec, 6.502 real sec
sorting block 3, #reads = 1091525 mem = 536880426 peak = 832225280
[M::process] read 719020 sequences (100000238 bp) in 2.566 CPU sec, 2.611 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 290077, 27, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 439, 5518)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 16200)
[M::mem_pestat] mean and std.dev: (1994.50, 2725.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 21541)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 198, 303)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 635)
[M::mem_pestat] mean and std.dev: (229.04, 121.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 801)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (131, 262, 1434)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4040)
[M::mem_pestat] mean and std.dev: (483.04, 538.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5343)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 259, 300)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 538)
[M::mem_pestat] mean and std.dev: (226.15, 65.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 657)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 719200 sequences (100000158 bp) in 2.080 CPU sec, 2.087 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (22, 290163, 23, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 362, 1090)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2946)
[M::mem_pestat] mean and std.dev: (559.95, 522.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3874)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 198, 302)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 632)
[M::mem_pestat] mean and std.dev: (228.88, 120.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 797)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1011, 1635, 3558)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8652)
[M::mem_pestat] mean and std.dev: (1837.57, 1496.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11199)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (234, 390, 752)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1788)
[M::mem_pestat] mean and std.dev: (464.16, 352.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2306)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 718944 reads in 186.187 CPU sec, 5.886 real sec
sorting block 4, #reads = 1091181 mem = 536880701 peak = 832225280
[M::mem_process_seqs] Processed 718662 reads in 219.199 CPU sec, 6.967 real sec
[M::process] read 719332 sequences (100000045 bp) in 2.278 CPU sec, 2.322 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 290164, 17, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 399, 1028)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2664)
[M::mem_pestat] mean and std.dev: (588.75, 475.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3482)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 197, 300)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 626)
[M::mem_pestat] mean and std.dev: (227.50, 119.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 789)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (420, 1095, 1726)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4338)
[M::mem_pestat] mean and std.dev: (770.79, 526.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5644)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 338, 723)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1767)
[M::mem_pestat] mean and std.dev: (374.41, 231.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2289)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 718402 sequences (100000151 bp) in 2.117 CPU sec, 2.120 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 289702, 34, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 408, 483)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1053)
[M::mem_pestat] mean and std.dev: (354.83, 176.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1338)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 197, 298)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 620)
[M::mem_pestat] mean and std.dev: (226.34, 118.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 781)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (112, 451, 952)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2632)
[M::mem_pestat] mean and std.dev: (487.70, 503.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3472)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (296, 348, 833)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1907)
[M::mem_pestat] mean and std.dev: (543.62, 511.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2589)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23, 289865, 5, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 269, 766)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1896)
[M::mem_pestat] mean and std.dev: (486.43, 404.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2461)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 196, 298)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 622)
[M::mem_pestat] mean and std.dev: (226.46, 118.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 784)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 293, 534)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1150)
[M::mem_pestat] mean and std.dev: (350.18, 206.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1458)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 719020 reads in 265.575 CPU sec, 8.462 real sec
sorting block 5, #reads = 1090939 mem = 536876566 peak = 841474048
[M::mem_process_seqs] Processed 719200 reads in 209.166 CPU sec, 6.699 real sec
[M::mem_process_seqs] Processed 719332 reads in 237.235 CPU sec, 7.604 real sec
sorting block 6, #reads = 1090447 mem = 536882277 peak = 948776960
[M::process] read 718372 sequences (100000246 bp) in 2.888 CPU sec, 3.002 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 289706, 19, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (226, 383, 1455)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3913)
[M::mem_pestat] mean and std.dev: (901.89, 996.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5142)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 198, 302)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 632)
[M::mem_pestat] mean and std.dev: (228.50, 120.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 797)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (239, 963, 4514)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13064)
[M::mem_pestat] mean and std.dev: (1831.84, 2095.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17339)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 369, 592)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1336)
[M::mem_pestat] mean and std.dev: (382.31, 211.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1708)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 717420 sequences (100000016 bp) in 1.860 CPU sec, 1.887 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 289511, 26, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 398, 708)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1720)
[M::mem_pestat] mean and std.dev: (503.71, 406.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2226)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 199, 303)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 635)
[M::mem_pestat] mean and std.dev: (229.14, 120.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 801)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (400, 1115, 1997)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5191)
[M::mem_pestat] mean and std.dev: (1168.20, 1118.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6788)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 230, 421)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 945)
[M::mem_pestat] mean and std.dev: (300.28, 168.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1207)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 716478 sequences (100000062 bp) in 1.600 CPU sec, 1.604 real sec...
[M::mem_process_seqs] Processed 718402 reads in 196.242 CPU sec, 6.225 real sec
sorting block 7, #reads = 1090270 mem = 536878578 peak = 948776960
[M::mem_process_seqs] Processed 718372 reads in 138.393 CPU sec, 4.382 real sec
sorting block 8, #reads = 1090426 mem = 536885066 peak = 963563520
[M::process] read 717176 sequences (100000133 bp) in 2.484 CPU sec, 2.558 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 288795, 16, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 219, 501)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1201)
[M::mem_pestat] mean and std.dev: (313.23, 252.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1551)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (139, 202, 307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 643)
[M::mem_pestat] mean and std.dev: (232.16, 121.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 811)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (98, 639, 1424)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4076)
[M::mem_pestat] mean and std.dev: (409.69, 433.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5402)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (242, 360, 874)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2138)
[M::mem_pestat] mean and std.dev: (496.21, 312.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2770)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 716490 sequences (100000272 bp) in 2.270 CPU sec, 2.276 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (22, 289531, 23, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 295, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 588)
[M::mem_pestat] mean and std.dev: (249.68, 87.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 714)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 201, 305)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 639)
[M::mem_pestat] mean and std.dev: (230.99, 121.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 806)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (401, 550, 1697)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4289)
[M::mem_pestat] mean and std.dev: (1106.09, 1120.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5590)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 301, 491)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1087)
[M::mem_pestat] mean and std.dev: (268.87, 160.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1385)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 716478 reads in 182.917 CPU sec, 5.783 real sec
[M::mem_process_seqs] Processed 717420 reads in 210.090 CPU sec, 6.665 real sec
sorting block 9, #reads = 1089565 mem = 536890682 peak = 963563520
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 289730, 10, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 293, 1104)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2950)
[M::mem_pestat] mean and std.dev: (491.63, 509.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3873)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 201, 304)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 636)
[M::mem_pestat] mean and std.dev: (230.55, 120.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 802)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (242, 1434, 1751)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4769)
[M::mem_pestat] mean and std.dev: (1088.89, 714.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6278)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 327, 1068)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2788)
[M::mem_pestat] mean and std.dev: (677.18, 685.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3648)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 716046 sequences (100000111 bp) in 2.861 CPU sec, 2.926 real sec...
[M::process] read 715744 sequences (100000217 bp) in 2.170 CPU sec, 2.172 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 289369, 11, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 336, 586)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1438)
[M::mem_pestat] mean and std.dev: (345.66, 256.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1864)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (139, 202, 305)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 637)
[M::mem_pestat] mean and std.dev: (231.18, 120.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 803)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (113, 362, 1417)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4025)
[M::mem_pestat] mean and std.dev: (749.64, 721.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5329)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 264, 347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 703)
[M::mem_pestat] mean and std.dev: (254.74, 111.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 881)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 717176 reads in 183.588 CPU sec, 5.794 real sec
sorting block 10, #reads = 1090219 mem = 536878348 peak = 963563520
[M::mem_process_seqs] Processed 716490 reads in 217.934 CPU sec, 6.911 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (21, 289294, 20, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (377, 617, 1522)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3812)
[M::mem_pestat] mean and std.dev: (1017.95, 954.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4957)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (139, 203, 308)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 646)
[M::mem_pestat] mean and std.dev: (233.25, 122.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 815)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 365, 2274)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6426)
[M::mem_pestat] mean and std.dev: (879.10, 1010.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8502)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 413, 853)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2167)
[M::mem_pestat] mean and std.dev: (556.03, 465.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2824)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 718868 sequences (100000154 bp) in 2.967 CPU sec, 3.030 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 288993, 19, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 292, 1183)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3139)
[M::mem_pestat] mean and std.dev: (652.59, 667.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4117)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (140, 204, 311)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 653)
[M::mem_pestat] mean and std.dev: (234.80, 124.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 824)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 542, 1658)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4622)
[M::mem_pestat] mean and std.dev: (1030.53, 1142.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6104)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 219, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 653)
[M::mem_pestat] mean and std.dev: (219.91, 71.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 811)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723620 sequences (100000168 bp) in 2.180 CPU sec, 2.182 real sec...
[M::mem_process_seqs] Processed 716046 reads in 183.838 CPU sec, 5.800 real sec
sorting block 11, #reads = 1089955 mem = 536880252 peak = 963563520
[M::mem_process_seqs] Processed 715744 reads in 208.498 CPU sec, 6.605 real sec
sorting block 12, #reads = 1088846 mem = 536879372 peak = 963563520
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 290027, 22, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (230, 314, 597)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1331)
[M::mem_pestat] mean and std.dev: (302.44, 148.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1698)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 198, 302)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 632)
[M::mem_pestat] mean and std.dev: (228.26, 120.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 797)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 1185, 1311)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3591)
[M::mem_pestat] mean and std.dev: (1035.64, 862.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4731)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 402, 682)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1636)
[M::mem_pestat] mean and std.dev: (451.41, 351.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2113)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722324 sequences (100000190 bp) in 2.874 CPU sec, 2.984 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 291293, 13, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (254, 342, 478)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 926)
[M::mem_pestat] mean and std.dev: (321.81, 160.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1150)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 190, 289)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 601)
[M::mem_pestat] mean and std.dev: (219.43, 114.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 757)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (392, 861, 1113)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2555)
[M::mem_pestat] mean and std.dev: (819.38, 417.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3276)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 278, 472)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1030)
[M::mem_pestat] mean and std.dev: (300.77, 190.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1309)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 721698 sequences (100000281 bp) in 2.210 CPU sec, 2.206 real sec...
[M::mem_process_seqs] Processed 718868 reads in 183.960 CPU sec, 6.049 real sec
[M::mem_process_seqs] Processed 723620 reads in 130.127 CPU sec, 4.128 real sec
sorting block 13, #reads = 1089319 mem = 536880054 peak = 963563520
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 291444, 16, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 291, 1454)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3964)
[M::mem_pestat] mean and std.dev: (530.05, 511.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5219)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 193, 295)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 617)
[M::mem_pestat] mean and std.dev: (223.29, 117.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 778)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (50, 943, 1224)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3572)
[M::mem_pestat] mean and std.dev: (747.25, 639.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4746)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 354, 748)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1918)
[M::mem_pestat] mean and std.dev: (394.33, 307.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2503)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720580 sequences (100000028 bp) in 2.728 CPU sec, 2.795 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 290572, 12, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (245, 459, 993)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2489)
[M::mem_pestat] mean and std.dev: (480.31, 348.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3237)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 194, 296)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 618)
[M::mem_pestat] mean and std.dev: (224.00, 118.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 779)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (232, 362, 805)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1951)
[M::mem_pestat] mean and std.dev: (371.60, 239.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2524)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 358, 1176)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3142)
[M::mem_pestat] mean and std.dev: (800.79, 917.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4473)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720362 sequences (100000260 bp) in 2.220 CPU sec, 2.217 real sec...
[M::mem_process_seqs] Processed 722324 reads in 182.188 CPU sec, 5.758 real sec
sorting block 14, #reads = 1095015 mem = 536878071 peak = 963563520
[M::mem_process_seqs] Processed 721698 reads in 127.709 CPU sec, 4.315 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 290599, 12, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (134, 189, 413)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 971)
[M::mem_pestat] mean and std.dev: (236.68, 168.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1250)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 195, 300)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 630)
[M::mem_pestat] mean and std.dev: (226.35, 119.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 795)
[M::process] read 720246 sequences (100000233 bp) in 2.621 CPU sec, 2.688 real sec...
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (70, 393, 3447)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10201)
[M::mem_pestat] mean and std.dev: (1986.25, 2762.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13578)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 282, 778)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1898)
[M::mem_pestat] mean and std.dev: (395.41, 298.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2458)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 719186 sequences (100000169 bp) in 2.108 CPU sec, 2.191 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 290169, 17, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 312, 442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 952)
[M::mem_pestat] mean and std.dev: (305.06, 170.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1207)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 196, 301)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 631)
[M::mem_pestat] mean and std.dev: (227.48, 120.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 796)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (60, 333, 1998)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5874)
[M::mem_pestat] mean and std.dev: (667.27, 819.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7812)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 270, 556)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1278)
[M::mem_pestat] mean and std.dev: (366.22, 283.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1639)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 720580 reads in 191.853 CPU sec, 6.342 real sec
sorting block 15, #reads = 1094577 mem = 536888020 peak = 963563520
[M::mem_process_seqs] Processed 720362 reads in 132.330 CPU sec, 4.211 real sec
sorting block 16, #reads = 1091342 mem = 536877625 peak = 980180992
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 290595, 19, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (139, 216, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 739)
[M::mem_pestat] mean and std.dev: (225.78, 118.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 939)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 197, 301)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 631)
[M::mem_pestat] mean and std.dev: (227.65, 121.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 796)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (235, 766, 1564)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4222)
[M::mem_pestat] mean and std.dev: (950.74, 954.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5551)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (273, 372, 532)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1050)
[M::mem_pestat] mean and std.dev: (358.82, 180.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1309)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 719152 sequences (100000134 bp) in 2.342 CPU sec, 2.414 real sec...
[M::process] read 719122 sequences (100000162 bp) in 1.700 CPU sec, 1.701 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 289813, 22, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 436, 1762)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4956)
[M::mem_pestat] mean and std.dev: (1213.16, 1270.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6553)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 198, 302)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 634)
[M::mem_pestat] mean and std.dev: (228.72, 121.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 800)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (610, 1602, 2451)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6133)
[M::mem_pestat] mean and std.dev: (1525.95, 1237.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7974)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 292, 734)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1760)
[M::mem_pestat] mean and std.dev: (297.81, 157.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2273)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 720246 reads in 182.803 CPU sec, 5.811 real sec
[M::mem_process_seqs] Processed 719186 reads in 136.385 CPU sec, 4.367 real sec
sorting block 17, #reads = 1092765 mem = 536880340 peak = 980180992
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 290475, 12, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 365, 1436)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3916)
[M::mem_pestat] mean and std.dev: (749.49, 810.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5156)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 198, 305)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 641)
[M::mem_pestat] mean and std.dev: (229.92, 122.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 809)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1140, 1590, 1590)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (240, 2490)
[M::mem_pestat] mean and std.dev: (1348.80, 412.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3000)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 290, 1089)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2817)
[M::mem_pestat] mean and std.dev: (489.00, 542.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3681)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 719214 sequences (100000187 bp) in 2.820 CPU sec, 2.902 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 290046, 24, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 485, 972)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2468)
[M::mem_pestat] mean and std.dev: (554.42, 430.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3216)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 197, 302)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 632)
[M::mem_pestat] mean and std.dev: (228.44, 121.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 797)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (227, 709, 762)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1832)
[M::mem_pestat] mean and std.dev: (493.41, 316.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2367)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (141, 204, 741)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1941)
[M::mem_pestat] mean and std.dev: (348.12, 350.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2541)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 719354 sequences (100000044 bp) in 1.780 CPU sec, 1.774 real sec...
[M::mem_process_seqs] Processed 719152 reads in 181.149 CPU sec, 5.755 real sec
sorting block 18, #reads = 1092142 mem = 536880552 peak = 980180992
[M::mem_process_seqs] Processed 719122 reads in 133.047 CPU sec, 4.254 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 290117, 28, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 312, 904)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2310)
[M::mem_pestat] mean and std.dev: (532.72, 476.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3013)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 197, 299)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 623)
[M::mem_pestat] mean and std.dev: (226.72, 118.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 785)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (448, 741, 2705)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7219)
[M::mem_pestat] mean and std.dev: (1565.50, 1555.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9476)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (245, 488, 652)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1466)
[M::mem_pestat] mean and std.dev: (457.29, 291.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1873)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 719280 sequences (100000208 bp) in 2.571 CPU sec, 2.638 real sec...
[M::process] read 718868 sequences (100000117 bp) in 1.750 CPU sec, 1.750 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 290023, 16, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 352, 1123)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3057)
[M::mem_pestat] mean and std.dev: (714.80, 854.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4135)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 196, 299)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 623)
[M::mem_pestat] mean and std.dev: (226.46, 119.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 785)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (367, 1104, 1384)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3418)
[M::mem_pestat] mean and std.dev: (837.29, 700.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4435)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (281, 649, 1017)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2489)
[M::mem_pestat] mean and std.dev: (625.38, 463.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3225)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 719214 reads in 179.001 CPU sec, 5.692 real sec
sorting block 19, #reads = 1092423 mem = 536877730 peak = 980180992
[M::mem_process_seqs] Processed 719354 reads in 126.167 CPU sec, 4.255 real sec
sorting block 20, #reads = 1089796 mem = 536877886 peak = 980180992
[M::process] read 718694 sequences (100000050 bp) in 2.808 CPU sec, 2.862 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 290231, 14, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 268, 441)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 927)
[M::mem_pestat] mean and std.dev: (265.30, 132.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1170)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 197, 300)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 626)
[M::mem_pestat] mean and std.dev: (227.45, 119.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 789)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (402, 998, 1018)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2250)
[M::mem_pestat] mean and std.dev: (791.77, 468.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2866)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 398, 1722)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4764)
[M::mem_pestat] mean and std.dev: (814.19, 1062.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6285)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 718086 sequences (100000168 bp) in 2.340 CPU sec, 2.342 real sec...
[M::mem_process_seqs] Processed 718868 reads in 107.047 CPU sec, 3.371 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 290051, 18, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 272, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 797)
[M::mem_pestat] mean and std.dev: (249.58, 112.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1013)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 196, 299)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 625)
[M::mem_pestat] mean and std.dev: (226.78, 119.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 788)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (105, 532, 1027)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2871)
[M::mem_pestat] mean and std.dev: (589.44, 462.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3793)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 452, 560)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1336)
[M::mem_pestat] mean and std.dev: (405.06, 313.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1724)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 290324, 17, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 283, 689)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1745)
[M::mem_pestat] mean and std.dev: (357.00, 261.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2273)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 197, 301)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 629)
[M::mem_pestat] mean and std.dev: (227.86, 120.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 793)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 1082, 3553)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10267)
[M::mem_pestat] mean and std.dev: (1852.59, 2142.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13624)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 443, 2009)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5599)
[M::mem_pestat] mean and std.dev: (934.64, 1013.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7394)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 718414 sequences (100000057 bp) in 2.486 CPU sec, 2.492 real sec...
[M::mem_process_seqs] Processed 719280 reads in 290.219 CPU sec, 9.399 real sec
sorting block 21, #reads = 1090584 mem = 536879049 peak = 980180992
[M::mem_process_seqs] Processed 718694 reads in 155.661 CPU sec, 4.957 real sec
sorting block 22, #reads = 1090388 mem = 536878715 peak = 980180992
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 289357, 12, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 266, 658)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1594)
[M::mem_pestat] mean and std.dev: (393.11, 372.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2062)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 198, 301)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 629)
[M::mem_pestat] mean and std.dev: (228.25, 119.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 793)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (97, 525, 1113)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3145)
[M::mem_pestat] mean and std.dev: (683.64, 871.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4168)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 670, 1364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3646)
[M::mem_pestat] mean and std.dev: (661.79, 455.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4787)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 717654 sequences (100000134 bp) in 2.949 CPU sec, 3.058 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 290058, 5, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 284, 1457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4041)
[M::mem_pestat] mean and std.dev: (631.14, 653.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5333)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 199, 304)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 638)
[M::mem_pestat] mean and std.dev: (230.14, 121.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 805)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 258, 1308)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3518)
[M::mem_pestat] mean and std.dev: (722.84, 832.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4623)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 717580 sequences (100000063 bp) in 2.240 CPU sec, 2.236 real sec...
[M::mem_process_seqs] Processed 718086 reads in 190.898 CPU sec, 6.047 real sec
[M::mem_process_seqs] Processed 718414 reads in 127.823 CPU sec, 4.040 real sec
sorting block 23, #reads = 1089846 mem = 536880306 peak = 980180992
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 289886, 18, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 480, 1330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3640)
[M::mem_pestat] mean and std.dev: (736.61, 825.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4795)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 200, 305)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 639)
[M::mem_pestat] mean and std.dev: (230.66, 121.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 806)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (34, 118, 269)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 739)
[M::mem_pestat] mean and std.dev: (151.25, 157.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 974)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 333, 752)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1876)
[M::mem_pestat] mean and std.dev: (391.55, 291.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2438)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 716126 sequences (100000265 bp) in 2.866 CPU sec, 2.960 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 289697, 17, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 546, 1457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4003)
[M::mem_pestat] mean and std.dev: (748.46, 615.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5276)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 200, 305)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 639)
[M::mem_pestat] mean and std.dev: (230.82, 121.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 806)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 386, 1919)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5421)
[M::mem_pestat] mean and std.dev: (1188.71, 1702.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7997)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 269, 463)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1041)
[M::mem_pestat] mean and std.dev: (296.83, 194.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1330)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 716708 sequences (100000056 bp) in 2.260 CPU sec, 2.260 real sec...
[M::mem_process_seqs] Processed 717654 reads in 186.812 CPU sec, 5.974 real sec
sorting block 24, #reads = 1089633 mem = 536889343 peak = 980180992
[M::mem_process_seqs] Processed 717580 reads in 128.732 CPU sec, 4.238 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 289205, 21, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 249, 1345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3697)
[M::mem_pestat] mean and std.dev: (787.53, 954.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4873)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (139, 203, 308)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 646)
[M::mem_pestat] mean and std.dev: (233.15, 122.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 815)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (105, 456, 1392)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3966)
[M::mem_pestat] mean and std.dev: (671.00, 764.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5253)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 258, 1110)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3034)
[M::mem_pestat] mean and std.dev: (578.38, 736.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3996)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722772 sequences (100000290 bp) in 2.799 CPU sec, 2.863 real sec...
[M::process] read 722710 sequences (100000273 bp) in 1.710 CPU sec, 1.715 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 288934, 30, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 431, 1576)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4374)
[M::mem_pestat] mean and std.dev: (848.17, 1048.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5773)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (139, 203, 311)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 655)
[M::mem_pestat] mean and std.dev: (234.50, 125.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 827)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 956, 1367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3761)
[M::mem_pestat] mean and std.dev: (864.10, 698.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4958)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 318, 445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 881)
[M::mem_pestat] mean and std.dev: (348.61, 176.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1099)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 716126 reads in 186.930 CPU sec, 6.079 real sec
sorting block 25, #reads = 1090294 mem = 536881049 peak = 980180992
[M::mem_process_seqs] Processed 716708 reads in 126.916 CPU sec, 4.177 real sec
sorting block 26, #reads = 1088938 mem = 536885510 peak = 980180992
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 291755, 8, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 418, 1079)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2841)
[M::mem_pestat] mean and std.dev: (530.20, 426.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3722)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 192, 291)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 605)
[M::mem_pestat] mean and std.dev: (221.11, 115.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 762)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 388, 871)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2203)
[M::mem_pestat] mean and std.dev: (448.40, 343.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2869)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 721658 sequences (100000092 bp) in 2.836 CPU sec, 2.908 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 291291, 13, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 239, 569)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1301)
[M::mem_pestat] mean and std.dev: (318.30, 251.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1667)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 192, 291)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 605)
[M::mem_pestat] mean and std.dev: (220.74, 114.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 762)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (227, 249, 2591)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7319)
[M::mem_pestat] mean and std.dev: (458.73, 686.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9683)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 370, 926)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2420)
[M::mem_pestat] mean and std.dev: (528.18, 418.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3167)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 721226 sequences (100000174 bp) in 2.290 CPU sec, 2.286 real sec...
[M::mem_process_seqs] Processed 722772 reads in 192.210 CPU sec, 6.212 real sec
[M::mem_process_seqs] Processed 722710 reads in 129.588 CPU sec, 4.110 real sec
sorting block 27, #reads = 1092383 mem = 536882829 peak = 980180992
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 290721, 13, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 281, 976)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2600)
[M::mem_pestat] mean and std.dev: (452.52, 480.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3412)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 193, 293)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 609)
[M::mem_pestat] mean and std.dev: (222.75, 116.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 767)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (668, 1053, 3333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8663)
[M::mem_pestat] mean and std.dev: (1369.00, 957.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11328)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 500, 2954)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8406)
[M::mem_pestat] mean and std.dev: (1577.20, 1752.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11132)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720758 sequences (100000193 bp) in 2.706 CPU sec, 2.759 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 290944, 21, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 306, 708)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1790)
[M::mem_pestat] mean and std.dev: (442.26, 358.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2331)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 194, 296)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 618)
[M::mem_pestat] mean and std.dev: (224.55, 117.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 779)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (777, 782, 9643)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 27375)
[M::mem_pestat] mean and std.dev: (3579.57, 4219.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 36241)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (266, 365, 970)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2378)
[M::mem_pestat] mean and std.dev: (483.52, 408.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3082)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720070 sequences (100000117 bp) in 2.270 CPU sec, 2.273 real sec...
[M::mem_process_seqs] Processed 721658 reads in 190.437 CPU sec, 6.072 real sec
sorting block 28, #reads = 1092112 mem = 536880357 peak = 980180992
[M::mem_process_seqs] Processed 721226 reads in 129.363 CPU sec, 4.114 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 290917, 22, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 387, 940)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2398)
[M::mem_pestat] mean and std.dev: (670.09, 622.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3162)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 196, 299)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 627)
[M::mem_pestat] mean and std.dev: (226.27, 119.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 791)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 356, 767)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1917)
[M::mem_pestat] mean and std.dev: (470.25, 457.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2492)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 291, 598)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1432)
[M::mem_pestat] mean and std.dev: (392.36, 348.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1849)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 719178 sequences (100000028 bp) in 2.832 CPU sec, 2.914 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 290765, 24, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 351, 1017)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2671)
[M::mem_pestat] mean and std.dev: (549.69, 439.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3498)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 197, 299)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 625)
[M::mem_pestat] mean and std.dev: (226.70, 118.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 788)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (133, 380, 908)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2458)
[M::mem_pestat] mean and std.dev: (423.41, 348.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3233)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 285, 691)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1719)
[M::mem_pestat] mean and std.dev: (376.09, 250.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2233)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 718998 sequences (100000211 bp) in 2.340 CPU sec, 2.343 real sec...
[M::mem_process_seqs] Processed 720758 reads in 180.062 CPU sec, 5.700 real sec
sorting block 29, #reads = 1092571 mem = 536879143 peak = 980180992
[M::mem_process_seqs] Processed 720070 reads in 128.358 CPU sec, 4.357 real sec
sorting block 30, #reads = 1091494 mem = 536879900 peak = 980180992
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 290466, 11, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 231, 616)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1426)
[M::mem_pestat] mean and std.dev: (399.74, 340.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1831)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 198, 303)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 635)
[M::mem_pestat] mean and std.dev: (229.25, 121.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 801)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (573, 1011, 2323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5823)
[M::mem_pestat] mean and std.dev: (1203.73, 715.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7573)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 271, 778)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1898)
[M::mem_pestat] mean and std.dev: (409.49, 325.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2458)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 718712 sequences (100000095 bp) in 2.720 CPU sec, 2.764 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (18, 290348, 19, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 438, 1555)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4285)
[M::mem_pestat] mean and std.dev: (727.47, 694.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5650)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 199, 304)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 638)
[M::mem_pestat] mean and std.dev: (229.87, 121.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 805)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 1039, 8250)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 24344)
[M::mem_pestat] mean and std.dev: (2699.84, 3478.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 32391)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 287, 2441)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6955)
[M::mem_pestat] mean and std.dev: (768.29, 1139.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9212)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 718692 sequences (100000106 bp) in 2.220 CPU sec, 2.222 real sec...
[M::mem_process_seqs] Processed 719178 reads in 184.435 CPU sec, 6.114 real sec
[M::mem_process_seqs] Processed 718998 reads in 126.030 CPU sec, 3.995 real sec
sorting block 31, #reads = 1090934 mem = 536883530 peak = 980180992
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 289793, 15, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 237, 744)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1894)
[M::mem_pestat] mean and std.dev: (401.61, 383.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2469)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 199, 304)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 638)
[M::mem_pestat] mean and std.dev: (230.12, 121.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 805)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (528, 1480, 3050)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8094)
[M::mem_pestat] mean and std.dev: (2046.60, 1847.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10616)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (247, 388, 1148)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2950)
[M::mem_pestat] mean and std.dev: (672.64, 544.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3851)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 718844 sequences (100000216 bp) in 2.860 CPU sec, 2.940 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 290095, 18, 21)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 307, 1073)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2811)
[M::mem_pestat] mean and std.dev: (690.29, 675.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3680)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 198, 303)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 635)
[M::mem_pestat] mean and std.dev: (229.42, 121.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 801)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (79, 237, 1134)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3244)
[M::mem_pestat] mean and std.dev: (442.56, 471.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4299)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 212, 598)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1478)
[M::mem_pestat] mean and std.dev: (326.75, 249.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1918)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 718910 sequences (100000072 bp) in 2.230 CPU sec, 2.233 real sec...
[M::mem_process_seqs] Processed 718712 reads in 187.116 CPU sec, 6.007 real sec
sorting block 32, #reads = 1091696 mem = 536882672 peak = 980180992
[M::mem_process_seqs] Processed 718692 reads in 134.451 CPU sec, 4.271 real sec
[M::process] read 718868 sequences (100000212 bp) in 2.268 CPU sec, 2.339 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 289959, 27, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 318, 1073)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2901)
[M::mem_pestat] mean and std.dev: (552.00, 579.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3815)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 198, 301)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 629)
[M::mem_pestat] mean and std.dev: (228.29, 119.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 793)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1179, 1628, 2530)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5232)
[M::mem_pestat] mean and std.dev: (1489.04, 907.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6583)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 441, 1313)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3487)
[M::mem_pestat] mean and std.dev: (765.42, 705.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4574)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 718392 sequences (100000147 bp) in 1.708 CPU sec, 1.706 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 289800, 19, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (227, 370, 905)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2261)
[M::mem_pestat] mean and std.dev: (555.78, 509.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2939)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 198, 300)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 626)
[M::mem_pestat] mean and std.dev: (227.92, 119.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 789)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (359, 1117, 2349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6329)
[M::mem_pestat] mean and std.dev: (1274.47, 1158.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8319)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (271, 482, 1568)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4162)
[M::mem_pestat] mean and std.dev: (1012.74, 1111.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5460)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 718844 reads in 184.397 CPU sec, 5.870 real sec
sorting block 33, #reads = 1088818 mem = 536884111 peak = 980180992
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 289673, 13, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 283, 752)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1946)
[M::mem_pestat] mean and std.dev: (436.13, 402.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2543)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 197, 300)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 626)
[M::mem_pestat] mean and std.dev: (227.45, 119.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 789)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (511, 1024, 3101)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8281)
[M::mem_pestat] mean and std.dev: (1631.46, 1368.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10871)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 290, 449)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 911)
[M::mem_pestat] mean and std.dev: (303.51, 141.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1142)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 718868 reads in 207.990 CPU sec, 6.588 real sec
[M::process] read 718424 sequences (100000163 bp) in 2.725 CPU sec, 2.741 real sec...
sorting block 34, #reads = 1091364 mem = 536880405 peak = 993128448
[M::mem_process_seqs] Processed 718910 reads in 233.872 CPU sec, 7.640 real sec
[M::process] read 718142 sequences (100000287 bp) in 2.237 CPU sec, 2.296 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 289177, 24, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 315, 1282)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3448)
[M::mem_pestat] mean and std.dev: (466.56, 520.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4531)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 198, 300)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 626)
[M::mem_pestat] mean and std.dev: (228.03, 119.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 789)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 430, 662)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1690)
[M::mem_pestat] mean and std.dev: (437.48, 391.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2204)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 286, 388)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 790)
[M::mem_pestat] mean and std.dev: (254.87, 122.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 991)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 717710 sequences (100000279 bp) in 1.668 CPU sec, 1.676 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (21, 289549, 26, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 425, 1210)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3240)
[M::mem_pestat] mean and std.dev: (766.90, 840.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4255)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 198, 303)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 635)
[M::mem_pestat] mean and std.dev: (229.09, 120.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 801)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (65, 662, 1287)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3731)
[M::mem_pestat] mean and std.dev: (739.62, 614.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4953)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 305, 589)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1333)
[M::mem_pestat] mean and std.dev: (356.97, 239.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1705)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 289871, 19, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 338, 701)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1687)
[M::mem_pestat] mean and std.dev: (392.03, 325.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2180)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 199, 303)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 633)
[M::mem_pestat] mean and std.dev: (229.63, 120.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 798)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (226, 798, 1731)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4741)
[M::mem_pestat] mean and std.dev: (800.00, 648.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6246)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (298, 398, 821)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1867)
[M::mem_pestat] mean and std.dev: (474.49, 335.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2390)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 718392 reads in 264.233 CPU sec, 8.665 real sec
sorting block 35, #reads = 1089854 mem = 536877870 peak = 993128448
[M::mem_process_seqs] Processed 718424 reads in 205.112 CPU sec, 6.582 real sec
[M::mem_process_seqs] Processed 718142 reads in 231.870 CPU sec, 7.451 real sec
sorting block 36, #reads = 1090483 mem = 536880637 peak = 1008009216
[M::process] read 717714 sequences (100000201 bp) in 3.020 CPU sec, 3.119 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 289420, 29, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 716, 1168)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3060)
[M::mem_pestat] mean and std.dev: (647.71, 477.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4006)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 199, 304)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 636)
[M::mem_pestat] mean and std.dev: (230.22, 121.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 802)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (430, 1276, 2135)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5545)
[M::mem_pestat] mean and std.dev: (1233.04, 996.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7250)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 206, 799)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2133)
[M::mem_pestat] mean and std.dev: (471.81, 502.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2800)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 717096 sequences (100000280 bp) in 2.599 CPU sec, 2.644 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 289798, 20, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 476, 1265)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3363)
[M::mem_pestat] mean and std.dev: (594.79, 498.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4412)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 200, 306)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 642)
[M::mem_pestat] mean and std.dev: (231.04, 122.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 810)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (256, 320, 891)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2161)
[M::mem_pestat] mean and std.dev: (502.33, 411.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2796)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 516, 998)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2566)
[M::mem_pestat] mean and std.dev: (612.86, 515.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3350)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 717710 reads in 187.462 CPU sec, 5.955 real sec
sorting block 37, #reads = 1089940 mem = 536887640 peak = 1008009216
[M::mem_process_seqs] Processed 717714 reads in 131.834 CPU sec, 4.143 real sec
[M::process] read 716090 sequences (100000120 bp) in 2.661 CPU sec, 2.731 real sec...
sorting block 38, #reads = 1091171 mem = 536882071 peak = 1008009216
[M::process] read 718088 sequences (100000242 bp) in 2.734 CPU sec, 2.763 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 288802, 20, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 386, 948)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2414)
[M::mem_pestat] mean and std.dev: (478.35, 436.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3147)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (139, 203, 310)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 652)
[M::mem_pestat] mean and std.dev: (234.12, 124.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 823)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 667, 1186)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3186)
[M::mem_pestat] mean and std.dev: (450.50, 356.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4186)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 270, 452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1004)
[M::mem_pestat] mean and std.dev: (277.81, 144.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1280)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 716090 reads in 98.228 CPU sec, 3.081 real sec
[M::process] read 723886 sequences (100000153 bp) in 1.980 CPU sec, 1.979 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 289676, 20, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 270, 912)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2320)
[M::mem_pestat] mean and std.dev: (324.95, 237.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3024)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (139, 201, 309)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 649)
[M::mem_pestat] mean and std.dev: (233.03, 123.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 819)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (102, 535, 764)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2088)
[M::mem_pestat] mean and std.dev: (517.40, 367.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2750)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (242, 417, 985)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2471)
[M::mem_pestat] mean and std.dev: (535.43, 476.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3214)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 289522, 18, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (138, 240, 368)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 828)
[M::mem_pestat] mean and std.dev: (261.36, 158.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1058)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 200, 304)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 636)
[M::mem_pestat] mean and std.dev: (229.82, 120.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 802)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (650, 2506, 4880)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13340)
[M::mem_pestat] mean and std.dev: (3140.44, 2621.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17570)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 349, 496)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1168)
[M::mem_pestat] mean and std.dev: (332.22, 228.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1504)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723018 sequences (100000126 bp) in 2.394 CPU sec, 2.401 real sec...
[M::mem_process_seqs] Processed 717096 reads in 279.440 CPU sec, 8.839 real sec
sorting block 39, #reads = 1089042 mem = 536879616 peak = 1008009216
[M::mem_process_seqs] Processed 718088 reads in 151.144 CPU sec, 4.785 real sec
sorting block 40, #reads = 1089751 mem = 536883641 peak = 1014071296
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 291431, 23, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 279, 855)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2181)
[M::mem_pestat] mean and std.dev: (411.62, 360.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2844)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 190, 288)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 598)
[M::mem_pestat] mean and std.dev: (218.75, 114.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 753)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (290, 919, 2743)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7649)
[M::mem_pestat] mean and std.dev: (1406.33, 1840.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10102)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 328, 592)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1370)
[M::mem_pestat] mean and std.dev: (340.38, 199.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1759)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722372 sequences (100000174 bp) in 3.060 CPU sec, 3.149 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 291573, 25, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (246, 326, 679)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1545)
[M::mem_pestat] mean and std.dev: (400.39, 228.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1978)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 191, 290)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 604)
[M::mem_pestat] mean and std.dev: (220.26, 115.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 761)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (59, 340, 1469)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4289)
[M::mem_pestat] mean and std.dev: (889.56, 1227.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5801)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 455, 854)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2156)
[M::mem_pestat] mean and std.dev: (473.10, 305.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2807)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 721784 sequences (100000253 bp) in 2.220 CPU sec, 2.220 real sec...
[M::mem_process_seqs] Processed 723886 reads in 182.303 CPU sec, 5.766 real sec
[M::mem_process_seqs] Processed 723018 reads in 127.344 CPU sec, 4.100 real sec
sorting block 41, #reads = 1093505 mem = 536878873 peak = 1014071296
[M::process] read 721350 sequences (100000162 bp) in 2.413 CPU sec, 2.485 real sec...
[M::process] read 721190 sequences (100000035 bp) in 1.668 CPU sec, 1.668 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 291286, 17, 22)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 261, 355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 743)
[M::mem_pestat] mean and std.dev: (213.55, 79.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 937)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 193, 294)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 614)
[M::mem_pestat] mean and std.dev: (223.08, 117.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 774)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 301, 1925)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5383)
[M::mem_pestat] mean and std.dev: (463.36, 481.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7112)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 357, 1465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4049)
[M::mem_pestat] mean and std.dev: (573.81, 519.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5341)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 721784 reads in 109.261 CPU sec, 3.487 real sec
sorting block 42, #reads = 1095052 mem = 536886624 peak = 1014071296
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 290597, 18, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 297, 1316)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3506)
[M::mem_pestat] mean and std.dev: (678.51, 759.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4601)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 192, 293)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 611)
[M::mem_pestat] mean and std.dev: (222.25, 116.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 770)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (343, 449, 1160)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2794)
[M::mem_pestat] mean and std.dev: (582.44, 498.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3611)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 361, 750)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1912)
[M::mem_pestat] mean and std.dev: (446.43, 309.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2493)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 291364, 9, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 381, 773)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1877)
[M::mem_pestat] mean and std.dev: (559.32, 478.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2472)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 194, 299)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 627)
[M::mem_pestat] mean and std.dev: (225.85, 120.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 791)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 224, 908)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2362)
[M::mem_pestat] mean and std.dev: (432.97, 443.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3089)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 722372 reads in 281.689 CPU sec, 8.996 real sec
[M::process] read 721204 sequences (100000140 bp) in 2.559 CPU sec, 2.571 real sec...
[M::mem_process_seqs] Processed 721350 reads in 226.468 CPU sec, 7.205 real sec
sorting block 43, #reads = 1093035 mem = 536882175 peak = 1014071296
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 290900, 20, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (300, 489, 638)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1314)
[M::mem_pestat] mean and std.dev: (416.34, 198.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1652)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 195, 298)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 624)
[M::mem_pestat] mean and std.dev: (225.66, 119.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 787)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (360, 831, 1501)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3783)
[M::mem_pestat] mean and std.dev: (766.56, 612.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4924)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (300, 412, 578)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1134)
[M::mem_pestat] mean and std.dev: (360.38, 141.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1412)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 719444 sequences (100000268 bp) in 3.027 CPU sec, 3.121 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 290745, 12, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (239, 297, 694)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1604)
[M::mem_pestat] mean and std.dev: (461.52, 337.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2059)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 194, 296)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 618)
[M::mem_pestat] mean and std.dev: (224.12, 118.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 779)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 307, 1082)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2886)
[M::mem_pestat] mean and std.dev: (538.00, 523.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3788)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 279, 2002)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5680)
[M::mem_pestat] mean and std.dev: (889.88, 1099.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7519)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 719440 sequences (100000019 bp) in 2.190 CPU sec, 2.188 real sec...
[M::mem_process_seqs] Processed 721190 reads in 176.493 CPU sec, 5.577 real sec
sorting block 44, #reads = 1092602 mem = 536877017 peak = 1014071296
[M::mem_process_seqs] Processed 721204 reads in 122.980 CPU sec, 4.022 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 290014, 14, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 244, 537)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1241)
[M::mem_pestat] mean and std.dev: (338.61, 238.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1593)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 197, 303)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 637)
[M::mem_pestat] mean and std.dev: (228.95, 121.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 804)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (394, 420, 721)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1375)
[M::mem_pestat] mean and std.dev: (405.91, 173.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1702)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 407, 1018)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2692)
[M::mem_pestat] mean and std.dev: (546.75, 452.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3529)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 719184 sequences (100000259 bp) in 2.869 CPU sec, 2.958 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 290273, 21, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 296, 815)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2071)
[M::mem_pestat] mean and std.dev: (331.03, 298.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2699)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 197, 303)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 637)
[M::mem_pestat] mean and std.dev: (229.33, 122.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 804)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (501, 992, 4071)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 11211)
[M::mem_pestat] mean and std.dev: (2161.29, 2423.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14781)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 300, 979)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2591)
[M::mem_pestat] mean and std.dev: (428.53, 322.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3397)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 719220 sequences (100000112 bp) in 2.200 CPU sec, 2.205 real sec...
[M::mem_process_seqs] Processed 719444 reads in 185.575 CPU sec, 5.992 real sec
sorting block 45, #reads = 1092928 mem = 536878205 peak = 1014071296
[M::mem_process_seqs] Processed 719440 reads in 129.700 CPU sec, 4.169 real sec
sorting block 46, #reads = 1090419 mem = 536879586 peak = 1023832064
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 289841, 23, 24)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 222, 436)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 952)
[M::mem_pestat] mean and std.dev: (228.26, 104.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1210)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 197, 302)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 634)
[M::mem_pestat] mean and std.dev: (228.62, 121.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 800)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 764, 1239)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3359)
[M::mem_pestat] mean and std.dev: (796.68, 781.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4419)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 221, 611)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1521)
[M::mem_pestat] mean and std.dev: (254.55, 172.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1976)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 719198 sequences (100000213 bp) in 2.756 CPU sec, 2.831 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 290181, 8, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 283, 820)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2122)
[M::mem_pestat] mean and std.dev: (517.63, 524.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2773)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 197, 300)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 626)
[M::mem_pestat] mean and std.dev: (227.34, 119.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 789)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 341, 774)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1868)
[M::mem_pestat] mean and std.dev: (399.49, 242.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2415)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 718902 sequences (100000121 bp) in 2.210 CPU sec, 2.213 real sec...
[M::mem_process_seqs] Processed 719184 reads in 189.883 CPU sec, 6.070 real sec
[M::mem_process_seqs] Processed 719220 reads in 130.650 CPU sec, 4.130 real sec
sorting block 47, #reads = 1091497 mem = 536879011 peak = 1023832064
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 289902, 19, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (277, 400, 535)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1051)
[M::mem_pestat] mean and std.dev: (373.88, 176.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1309)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 197, 299)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 625)
[M::mem_pestat] mean and std.dev: (226.99, 119.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 788)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 386, 2533)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7165)
[M::mem_pestat] mean and std.dev: (1147.83, 1336.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9481)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 291, 935)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2497)
[M::mem_pestat] mean and std.dev: (522.45, 562.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3278)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 718596 sequences (100000118 bp) in 2.808 CPU sec, 2.878 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 289777, 24, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (243, 392, 663)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1503)
[M::mem_pestat] mean and std.dev: (438.32, 327.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1923)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 197, 299)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 623)
[M::mem_pestat] mean and std.dev: (227.04, 119.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 785)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (270, 561, 1011)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2493)
[M::mem_pestat] mean and std.dev: (555.76, 456.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3234)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 224, 752)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1912)
[M::mem_pestat] mean and std.dev: (380.44, 350.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2492)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 718282 sequences (100000065 bp) in 2.310 CPU sec, 2.315 real sec...
[M::mem_process_seqs] Processed 719198 reads in 187.202 CPU sec, 5.971 real sec
sorting block 48, #reads = 1090660 mem = 536879427 peak = 1023832064
[M::mem_process_seqs] Processed 718902 reads in 133.124 CPU sec, 4.229 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 289538, 20, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 271, 839)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2195)
[M::mem_pestat] mean and std.dev: (490.89, 440.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2873)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 197, 299)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 623)
[M::mem_pestat] mean and std.dev: (227.16, 119.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 785)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (26, 277, 1196)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3536)
[M::mem_pestat] mean and std.dev: (616.20, 664.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4706)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 340, 1038)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2658)
[M::mem_pestat] mean and std.dev: (626.45, 611.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3468)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 717956 sequences (100000112 bp) in 2.405 CPU sec, 2.476 real sec...
[M::process] read 717288 sequences (100000237 bp) in 1.910 CPU sec, 1.909 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 290273, 17, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 278, 700)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1782)
[M::mem_pestat] mean and std.dev: (401.52, 320.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2323)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 198, 301)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 629)
[M::mem_pestat] mean and std.dev: (228.60, 120.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 793)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (323, 508, 1182)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2900)
[M::mem_pestat] mean and std.dev: (767.47, 697.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3759)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 354, 1216)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3202)
[M::mem_pestat] mean and std.dev: (512.66, 503.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4195)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 718596 reads in 183.473 CPU sec, 5.820 real sec
sorting block 49, #reads = 1091172 mem = 536878609 peak = 1023832064
[M::mem_process_seqs] Processed 718282 reads in 128.880 CPU sec, 4.099 real sec
sorting block 50, #reads = 1090266 mem = 536878622 peak = 1027006464
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 289857, 19, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 288, 818)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2132)
[M::mem_pestat] mean and std.dev: (431.64, 432.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2789)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 200, 304)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 636)
[M::mem_pestat] mean and std.dev: (230.14, 121.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 802)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (73, 408, 668)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1858)
[M::mem_pestat] mean and std.dev: (377.65, 398.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2453)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 207, 453)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1067)
[M::mem_pestat] mean and std.dev: (250.17, 141.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1374)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 717106 sequences (100000245 bp) in 2.734 CPU sec, 2.827 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 289294, 11, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 594, 2969)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8463)
[M::mem_pestat] mean and std.dev: (1489.51, 1459.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11210)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 200, 303)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 633)
[M::mem_pestat] mean and std.dev: (229.96, 120.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 798)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (574, 657, 1097)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2143)
[M::mem_pestat] mean and std.dev: (697.70, 309.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2666)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 376, 720)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1754)
[M::mem_pestat] mean and std.dev: (475.93, 381.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2271)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 716688 sequences (100000044 bp) in 2.210 CPU sec, 2.206 real sec...
[M::mem_process_seqs] Processed 717956 reads in 188.321 CPU sec, 6.082 real sec
[M::mem_process_seqs] Processed 717288 reads in 130.036 CPU sec, 4.136 real sec
sorting block 51, #reads = 1089908 mem = 536879851 peak = 1027006464
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 289855, 29, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (236, 328, 615)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1373)
[M::mem_pestat] mean and std.dev: (380.74, 217.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1752)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 201, 305)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 639)
[M::mem_pestat] mean and std.dev: (231.14, 121.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 806)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (146, 1017, 1458)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4082)
[M::mem_pestat] mean and std.dev: (834.52, 681.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5394)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (253, 391, 478)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 928)
[M::mem_pestat] mean and std.dev: (308.50, 99.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1153)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 716242 sequences (100000062 bp) in 2.631 CPU sec, 2.713 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 289279, 16, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (288, 548, 1062)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2610)
[M::mem_pestat] mean and std.dev: (541.59, 425.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3384)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (139, 202, 308)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 646)
[M::mem_pestat] mean and std.dev: (232.59, 122.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 815)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (269, 574, 1049)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2609)
[M::mem_pestat] mean and std.dev: (728.38, 549.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3389)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 378, 965)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2451)
[M::mem_pestat] mean and std.dev: (511.74, 411.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3194)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725984 sequences (100000284 bp) in 2.285 CPU sec, 2.285 real sec...
[M::mem_process_seqs] Processed 717106 reads in 181.255 CPU sec, 5.741 real sec
[M::mem_process_seqs] Processed 716688 reads in 136.270 CPU sec, 4.343 real sec
sorting block 52, #reads = 1090409 mem = 536880001 peak = 1027006464
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 289038, 19, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 262, 643)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1517)
[M::mem_pestat] mean and std.dev: (427.31, 371.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1954)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (139, 203, 310)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 652)
[M::mem_pestat] mean and std.dev: (234.42, 124.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 823)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (653, 1730, 3243)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8423)
[M::mem_pestat] mean and std.dev: (1913.17, 1755.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11013)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 243, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 623)
[M::mem_pestat] mean and std.dev: (221.70, 67.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 768)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 727810 sequences (100000133 bp) in 2.976 CPU sec, 3.026 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 292464, 7, 16)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 291, 603)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1453)
[M::mem_pestat] mean and std.dev: (387.16, 262.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1878)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 186, 280)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 578)
[M::mem_pestat] mean and std.dev: (213.34, 110.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 727)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (351, 886, 2257)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6069)
[M::mem_pestat] mean and std.dev: (1316.07, 1348.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7975)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 725992 sequences (100000085 bp) in 2.290 CPU sec, 2.290 real sec...
[M::mem_process_seqs] Processed 716242 reads in 190.623 CPU sec, 6.029 real sec
sorting block 53, #reads = 1089944 mem = 536880054 peak = 1027006464
[M::mem_process_seqs] Processed 725984 reads in 136.018 CPU sec, 4.298 real sec
sorting block 54, #reads = 1088955 mem = 536879408 peak = 1027006464
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 293389, 10, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 306, 982)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2604)
[M::mem_pestat] mean and std.dev: (532.95, 533.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3415)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 183, 276)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 568)
[M::mem_pestat] mean and std.dev: (210.28, 108.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 714)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (307, 747, 884)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2038)
[M::mem_pestat] mean and std.dev: (505.88, 260.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2615)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 371, 768)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1866)
[M::mem_pestat] mean and std.dev: (466.74, 385.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2415)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724764 sequences (100000032 bp) in 2.724 CPU sec, 2.762 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 293103, 4, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 266, 522)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1166)
[M::mem_pestat] mean and std.dev: (281.41, 186.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1488)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 186, 281)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 581)
[M::mem_pestat] mean and std.dev: (214.28, 111.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 731)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 345, 1523)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4175)
[M::mem_pestat] mean and std.dev: (803.45, 759.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5501)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 724162 sequences (100000049 bp) in 2.230 CPU sec, 2.236 real sec...
[M::mem_process_seqs] Processed 727810 reads in 187.785 CPU sec, 5.944 real sec
[M::mem_process_seqs] Processed 725992 reads in 129.136 CPU sec, 4.200 real sec
sorting block 55, #reads = 1097168 mem = 536880150 peak = 1027006464
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 292785, 16, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 251, 691)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1697)
[M::mem_pestat] mean and std.dev: (309.11, 222.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2200)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 188, 286)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 594)
[M::mem_pestat] mean and std.dev: (217.32, 114.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 748)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (60, 297, 1226)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3558)
[M::mem_pestat] mean and std.dev: (423.79, 528.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4724)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 273, 927)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2331)
[M::mem_pestat] mean and std.dev: (390.52, 351.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3033)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723128 sequences (100000163 bp) in 2.838 CPU sec, 2.886 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 292387, 10, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (250, 367, 579)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1237)
[M::mem_pestat] mean and std.dev: (383.15, 225.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1566)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 189, 287)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 597)
[M::mem_pestat] mean and std.dev: (218.48, 115.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 752)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (624, 1195, 1391)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2925)
[M::mem_pestat] mean and std.dev: (908.38, 334.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3692)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 342, 550)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1230)
[M::mem_pestat] mean and std.dev: (360.79, 218.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1570)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722796 sequences (100000089 bp) in 2.297 CPU sec, 2.307 real sec...
[M::mem_process_seqs] Processed 724764 reads in 197.106 CPU sec, 6.364 real sec
[M::mem_process_seqs] Processed 724162 reads in 141.256 CPU sec, 4.488 real sec
sorting block 56, #reads = 1095375 mem = 536880098 peak = 1027006464
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 291829, 11, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 305, 738)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1910)
[M::mem_pestat] mean and std.dev: (400.30, 349.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2496)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 191, 292)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 610)
[M::mem_pestat] mean and std.dev: (221.56, 117.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 769)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (399, 1416, 1799)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4599)
[M::mem_pestat] mean and std.dev: (1302.91, 1078.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5999)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 242, 894)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2360)
[M::mem_pestat] mean and std.dev: (466.97, 498.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3093)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722204 sequences (100000145 bp) in 2.706 CPU sec, 2.760 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 291716, 13, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (132, 236, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 723)
[M::mem_pestat] mean and std.dev: (228.74, 126.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 920)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 191, 293)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 613)
[M::mem_pestat] mean and std.dev: (222.24, 118.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 773)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (61, 662, 2324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6850)
[M::mem_pestat] mean and std.dev: (1096.54, 1222.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9113)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (266, 481, 1851)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5021)
[M::mem_pestat] mean and std.dev: (829.42, 853.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6606)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722062 sequences (100000282 bp) in 2.280 CPU sec, 2.276 real sec...
[M::mem_process_seqs] Processed 723128 reads in 184.374 CPU sec, 5.838 real sec
sorting block 57, #reads = 1092006 mem = 536879369 peak = 1027006464
[M::mem_process_seqs] Processed 722796 reads in 135.619 CPU sec, 4.319 real sec
sorting block 58, #reads = 1092618 mem = 536877185 peak = 1027006464
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 291470, 16, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 357, 1445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3913)
[M::mem_pestat] mean and std.dev: (807.83, 914.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5147)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 193, 295)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 617)
[M::mem_pestat] mean and std.dev: (223.93, 119.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 778)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (683, 2026, 3732)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9830)
[M::mem_pestat] mean and std.dev: (2377.25, 2192.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12879)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (280, 684, 1333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3439)
[M::mem_pestat] mean and std.dev: (652.72, 449.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4492)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720882 sequences (100000055 bp) in 2.941 CPU sec, 3.034 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 291715, 10, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 379, 1693)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4753)
[M::mem_pestat] mean and std.dev: (704.41, 753.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6283)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 192, 295)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 617)
[M::mem_pestat] mean and std.dev: (223.61, 119.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 778)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (60, 320, 843)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2409)
[M::mem_pestat] mean and std.dev: (304.50, 291.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3192)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 334, 1754)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4874)
[M::mem_pestat] mean and std.dev: (904.19, 1151.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6434)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 721070 sequences (100000053 bp) in 2.330 CPU sec, 2.334 real sec...
[M::mem_process_seqs] Processed 722204 reads in 186.111 CPU sec, 5.882 real sec
[M::mem_process_seqs] Processed 722062 reads in 129.922 CPU sec, 4.107 real sec
sorting block 59, #reads = 1092232 mem = 536884477 peak = 1027006464
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (22, 290287, 11, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 335, 837)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2169)
[M::mem_pestat] mean and std.dev: (477.95, 560.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2835)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 194, 298)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 622)
[M::mem_pestat] mean and std.dev: (225.79, 120.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 784)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (636, 1474, 2199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5325)
[M::mem_pestat] mean and std.dev: (1344.73, 780.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6888)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 390, 1595)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4453)
[M::mem_pestat] mean and std.dev: (474.21, 485.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5882)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720346 sequences (100000089 bp) in 3.142 CPU sec, 3.201 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 290987, 17, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 222, 572)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1396)
[M::mem_pestat] mean and std.dev: (392.14, 375.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1895)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 194, 298)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 624)
[M::mem_pestat] mean and std.dev: (225.65, 120.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 787)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (540, 827, 2707)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7041)
[M::mem_pestat] mean and std.dev: (1506.71, 1744.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9208)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 352, 1081)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2813)
[M::mem_pestat] mean and std.dev: (593.39, 576.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3679)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 719726 sequences (100000298 bp) in 2.309 CPU sec, 2.304 real sec...
[M::mem_process_seqs] Processed 720882 reads in 194.950 CPU sec, 6.159 real sec
sorting block 60, #reads = 1088916 mem = 536879747 peak = 1027006464
[M::mem_process_seqs] Processed 721070 reads in 138.862 CPU sec, 4.397 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 290204, 17, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 318, 694)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1682)
[M::mem_pestat] mean and std.dev: (397.39, 339.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2176)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 195, 298)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 622)
[M::mem_pestat] mean and std.dev: (226.13, 119.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 784)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 280, 644)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1512)
[M::mem_pestat] mean and std.dev: (385.71, 317.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1946)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 313, 710)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1682)
[M::mem_pestat] mean and std.dev: (413.87, 378.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2168)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720100 sequences (100000177 bp) in 2.882 CPU sec, 2.932 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 289813, 20, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 306, 2598)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7418)
[M::mem_pestat] mean and std.dev: (1570.60, 2106.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9995)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 195, 298)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 622)
[M::mem_pestat] mean and std.dev: (226.19, 119.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 784)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (533, 670, 2530)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6524)
[M::mem_pestat] mean and std.dev: (1147.70, 1099.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8521)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 822, 1289)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3443)
[M::mem_pestat] mean and std.dev: (836.95, 710.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4520)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 719412 sequences (100000260 bp) in 2.360 CPU sec, 2.358 real sec...
[M::mem_process_seqs] Processed 720346 reads in 197.881 CPU sec, 6.527 real sec
sorting block 61, #reads = 1089724 mem = 536878031 peak = 1027006464
[M::mem_process_seqs] Processed 719726 reads in 139.834 CPU sec, 4.452 real sec
sorting block 62, #reads = 1089767 mem = 536885553 peak = 1076908032
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 290159, 29, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 379, 577)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1381)
[M::mem_pestat] mean and std.dev: (337.81, 216.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1783)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 195, 297)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 619)
[M::mem_pestat] mean and std.dev: (225.91, 119.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 780)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (398, 955, 1622)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4070)
[M::mem_pestat] mean and std.dev: (1103.82, 1073.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5397)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 278, 1358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3710)
[M::mem_pestat] mean and std.dev: (591.96, 851.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4886)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 719370 sequences (100000062 bp) in 2.414 CPU sec, 2.468 real sec...
[M::process] read 719044 sequences (100000069 bp) in 1.870 CPU sec, 1.866 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 290369, 21, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 238, 496)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1138)
[M::mem_pestat] mean and std.dev: (289.30, 190.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1459)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 197, 301)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 631)
[M::mem_pestat] mean and std.dev: (228.17, 121.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 796)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (101, 328, 1688)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4862)
[M::mem_pestat] mean and std.dev: (732.10, 849.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6449)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 293, 857)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2237)
[M::mem_pestat] mean and std.dev: (511.50, 602.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2927)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 720100 reads in 194.378 CPU sec, 6.180 real sec
[M::mem_process_seqs] Processed 719412 reads in 137.173 CPU sec, 4.395 real sec
sorting block 63, #reads = 1088697 mem = 536877819 peak = 1076908032
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 290426, 25, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 406, 4042)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 11796)
[M::mem_pestat] mean and std.dev: (1836.94, 2492.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 15673)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 197, 298)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 622)
[M::mem_pestat] mean and std.dev: (226.77, 119.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 784)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (251, 547, 1251)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3251)
[M::mem_pestat] mean and std.dev: (629.88, 529.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4251)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 289, 973)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2563)
[M::mem_pestat] mean and std.dev: (434.15, 405.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3358)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 718998 sequences (100000237 bp) in 2.606 CPU sec, 2.655 real sec...
[M::process] read 719488 sequences (100000300 bp) in 1.880 CPU sec, 1.878 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 290011, 26, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 263, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 696)
[M::mem_pestat] mean and std.dev: (254.63, 108.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 865)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 197, 300)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 626)
[M::mem_pestat] mean and std.dev: (227.71, 119.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 789)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (275, 582, 1568)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4154)
[M::mem_pestat] mean and std.dev: (1025.33, 1067.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5447)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (230, 597, 1086)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2798)
[M::mem_pestat] mean and std.dev: (563.28, 428.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3654)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 719370 reads in 198.876 CPU sec, 6.337 real sec
sorting block 64, #reads = 1086296 mem = 536881509 peak = 1076908032
[M::mem_process_seqs] Processed 719044 reads in 140.439 CPU sec, 4.487 real sec
[M::process] read 719312 sequences (100000226 bp) in 2.416 CPU sec, 2.459 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 289626, 16, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (232, 349, 817)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1987)
[M::mem_pestat] mean and std.dev: (492.52, 377.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2572)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 197, 299)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 623)
[M::mem_pestat] mean and std.dev: (226.88, 119.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 785)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (425, 669, 994)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2132)
[M::mem_pestat] mean and std.dev: (534.08, 266.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2701)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 785, 2641)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7531)
[M::mem_pestat] mean and std.dev: (1201.16, 1331.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9976)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 731154 sequences (100000004 bp) in 1.830 CPU sec, 1.837 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23, 290398, 10, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (279, 324, 2092)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5718)
[M::mem_pestat] mean and std.dev: (1015.22, 1279.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7531)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 197, 300)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 626)
[M::mem_pestat] mean and std.dev: (227.16, 119.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 789)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (117, 646, 877)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2397)
[M::mem_pestat] mean and std.dev: (473.10, 355.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3157)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (241, 277, 708)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1642)
[M::mem_pestat] mean and std.dev: (514.71, 433.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2249)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 718998 reads in 194.780 CPU sec, 6.189 real sec
sorting block 65, #reads = 1089367 mem = 536876842 peak = 1076908032
[M::mem_process_seqs] Processed 719488 reads in 137.815 CPU sec, 4.397 real sec
sorting block 66, #reads = 1087149 mem = 536877675 peak = 1076908032
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 290080, 24, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 289, 2257)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6341)
[M::mem_pestat] mean and std.dev: (1115.37, 1550.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8383)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 196, 300)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 628)
[M::mem_pestat] mean and std.dev: (227.15, 120.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 792)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (428, 808, 1185)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2699)
[M::mem_pestat] mean and std.dev: (874.17, 647.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3463)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (242, 365, 598)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1310)
[M::mem_pestat] mean and std.dev: (370.96, 208.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1666)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 728320 sequences (100000114 bp) in 2.991 CPU sec, 3.022 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 294387, 9, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (145, 267, 651)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1663)
[M::mem_pestat] mean and std.dev: (350.46, 297.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2169)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 178, 264)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 536)
[M::mem_pestat] mean and std.dev: (202.25, 100.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 672)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 443, 879)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2183)
[M::mem_pestat] mean and std.dev: (613.97, 511.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2835)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 726580 sequences (100000152 bp) in 2.390 CPU sec, 2.391 real sec...
[M::mem_process_seqs] Processed 719312 reads in 208.643 CPU sec, 6.652 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 293593, 18, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (140, 295, 920)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2480)
[M::mem_pestat] mean and std.dev: (445.64, 540.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3260)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::process] read 726222 sequences (100000026 bp) in 2.706 CPU sec, 2.708 real sec...
[M::mem_pestat] (25, 50, 75) percentile: (130, 183, 273)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 559)
[M::mem_pestat] mean and std.dev: (208.69, 106.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 702)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (244, 473, 4136)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 11920)
[M::mem_pestat] mean and std.dev: (1821.61, 2065.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 15812)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 357, 2147)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6035)
[M::mem_pestat] mean and std.dev: (907.92, 1177.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7979)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 728320 reads in 113.325 CPU sec, 3.619 real sec
sorting block 67, #reads = 1087497 mem = 536880809 peak = 1076908032
[M::mem_process_seqs] Processed 731154 reads in 282.807 CPU sec, 8.998 real sec
sorting block 68, #reads = 1091358 mem = 536881231 peak = 1076908032
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 292777, 22, 18)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 328, 479)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1081)
[M::mem_pestat] mean and std.dev: (325.06, 201.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1382)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 185, 279)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 575)
[M::mem_pestat] mean and std.dev: (212.95, 109.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 723)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (138, 605, 795)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2109)
[M::mem_pestat] mean and std.dev: (439.78, 307.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2766)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 214, 288)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 522)
[M::mem_pestat] mean and std.dev: (219.71, 73.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 639)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726518 sequences (100000059 bp) in 3.165 CPU sec, 3.234 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 292776, 17, 18)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 548, 949)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2437)
[M::mem_pestat] mean and std.dev: (446.79, 353.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3181)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 185, 280)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 578)
[M::mem_pestat] mean and std.dev: (213.47, 110.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 727)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (244, 466, 2217)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6163)
[M::mem_pestat] mean and std.dev: (1299.82, 1595.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8136)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 250, 966)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2538)
[M::mem_pestat] mean and std.dev: (499.44, 579.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3324)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725490 sequences (100000212 bp) in 2.370 CPU sec, 2.366 real sec...
[M::mem_process_seqs] Processed 726580 reads in 236.934 CPU sec, 7.564 real sec
[M::process] read 724460 sequences (100000113 bp) in 2.520 CPU sec, 2.524 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 293020, 17, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 285, 542)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1236)
[M::mem_pestat] mean and std.dev: (342.88, 236.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1583)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 185, 278)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 572)
[M::mem_pestat] mean and std.dev: (212.52, 109.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 719)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 546, 2070)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5888)
[M::mem_pestat] mean and std.dev: (975.75, 1124.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7797)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 280, 1074)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2840)
[M::mem_pestat] mean and std.dev: (515.62, 511.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3723)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 726518 reads in 118.627 CPU sec, 3.886 real sec
sorting block 69, #reads = 1092456 mem = 536882988 peak = 1076908032
[M::mem_process_seqs] Processed 726222 reads in 299.363 CPU sec, 9.635 real sec
sorting block 70, #reads = 1090473 mem = 536879557 peak = 1076908032
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 292862, 22, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 279, 414)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 852)
[M::mem_pestat] mean and std.dev: (268.27, 123.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1071)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 187, 283)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 585)
[M::mem_pestat] mean and std.dev: (215.74, 112.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 736)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 1259, 1429)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3935)
[M::mem_pestat] mean and std.dev: (1005.67, 830.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5188)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 328, 1071)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2865)
[M::mem_pestat] mean and std.dev: (611.04, 659.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3762)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723654 sequences (100000021 bp) in 2.778 CPU sec, 3.071 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 292130, 21, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (273, 345, 2486)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6912)
[M::mem_pestat] mean and std.dev: (1203.52, 1406.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9125)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 189, 287)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 597)
[M::mem_pestat] mean and std.dev: (218.35, 114.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 752)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (306, 799, 2264)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6180)
[M::mem_pestat] mean and std.dev: (1083.00, 932.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8138)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 228, 1455)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4061)
[M::mem_pestat] mean and std.dev: (559.79, 663.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5364)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723562 sequences (100000110 bp) in 2.410 CPU sec, 2.404 real sec...
[M::mem_process_seqs] Processed 725490 reads in 233.631 CPU sec, 7.460 real sec
[M::mem_process_seqs] Processed 724460 reads in 137.524 CPU sec, 4.360 real sec
sorting block 71, #reads = 1091320 mem = 536879966 peak = 1076908032
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 291929, 18, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 267, 382)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 796)
[M::mem_pestat] mean and std.dev: (268.70, 154.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1003)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 189, 288)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 598)
[M::mem_pestat] mean and std.dev: (219.28, 115.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 753)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (118, 423, 1805)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5179)
[M::mem_pestat] mean and std.dev: (752.00, 744.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6866)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 360, 876)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2212)
[M::mem_pestat] mean and std.dev: (434.26, 375.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2880)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722524 sequences (100000147 bp) in 2.788 CPU sec, 2.876 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 292376, 19, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 364, 576)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1390)
[M::mem_pestat] mean and std.dev: (406.35, 313.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1797)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 191, 292)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 610)
[M::mem_pestat] mean and std.dev: (221.56, 117.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 769)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (238, 636, 1843)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5053)
[M::mem_pestat] mean and std.dev: (707.40, 652.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6658)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 727, 1057)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2787)
[M::mem_pestat] mean and std.dev: (523.94, 388.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3652)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 721478 sequences (100000200 bp) in 2.380 CPU sec, 2.371 real sec...
[M::mem_process_seqs] Processed 723654 reads in 196.778 CPU sec, 6.227 real sec
sorting block 72, #reads = 1091177 mem = 536880910 peak = 1076908032
[M::mem_process_seqs] Processed 723562 reads in 136.542 CPU sec, 4.317 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 291313, 28, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 240, 433)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 937)
[M::mem_pestat] mean and std.dev: (257.62, 114.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1189)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 192, 293)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 611)
[M::mem_pestat] mean and std.dev: (222.58, 118.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 770)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (136, 510, 1239)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3445)
[M::mem_pestat] mean and std.dev: (603.80, 543.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4548)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 516, 615)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1441)
[M::mem_pestat] mean and std.dev: (484.49, 347.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1874)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 721224 sequences (100000036 bp) in 2.911 CPU sec, 2.981 real sec...
[M::process] read 720902 sequences (100000048 bp) in 1.697 CPU sec, 1.698 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 291026, 16, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 565, 1167)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3057)
[M::mem_pestat] mean and std.dev: (633.00, 486.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4002)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 193, 295)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 615)
[M::mem_pestat] mean and std.dev: (223.76, 118.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 775)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (352, 1174, 2415)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6541)
[M::mem_pestat] mean and std.dev: (1369.47, 1409.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8604)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 368, 976)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2520)
[M::mem_pestat] mean and std.dev: (498.25, 503.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3292)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 722524 reads in 174.616 CPU sec, 5.527 real sec
sorting block 73, #reads = 1090091 mem = 536882798 peak = 1076908032
[M::mem_process_seqs] Processed 721478 reads in 197.037 CPU sec, 6.258 real sec
sorting block 74, #reads = 1088948 mem = 536880082 peak = 1078034432
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 290915, 24, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 250, 432)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 924)
[M::mem_pestat] mean and std.dev: (293.58, 176.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1170)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 193, 294)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 612)
[M::mem_pestat] mean and std.dev: (223.46, 117.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 771)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (943, 1455, 2774)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6436)
[M::mem_pestat] mean and std.dev: (1822.29, 1350.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8267)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (256, 350, 453)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 847)
[M::mem_pestat] mean and std.dev: (334.78, 165.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1044)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720476 sequences (100000191 bp) in 2.104 CPU sec, 2.164 real sec...
[M::process] read 720486 sequences (100000266 bp) in 1.756 CPU sec, 1.771 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 290603, 23, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 243, 1218)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3360)
[M::mem_pestat] mean and std.dev: (588.15, 649.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4431)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 194, 296)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 618)
[M::mem_pestat] mean and std.dev: (224.59, 118.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 779)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (507, 523, 701)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (119, 1089)
[M::mem_pestat] mean and std.dev: (497.78, 162.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1283)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (281, 404, 752)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1694)
[M::mem_pestat] mean and std.dev: (487.08, 374.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2165)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 721224 reads in 176.160 CPU sec, 5.593 real sec
[M::mem_process_seqs] Processed 720902 reads in 130.384 CPU sec, 4.158 real sec
sorting block 75, #reads = 1087777 mem = 536877537 peak = 1078034432
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 289839, 15, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (223, 580, 4737)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13765)
[M::mem_pestat] mean and std.dev: (1959.08, 2424.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 18279)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 194, 297)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 621)
[M::mem_pestat] mean and std.dev: (225.11, 118.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 783)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (254, 459, 984)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2444)
[M::mem_pestat] mean and std.dev: (611.93, 632.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3174)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 344, 994)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2544)
[M::mem_pestat] mean and std.dev: (565.39, 552.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3319)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 719808 sequences (100000256 bp) in 2.727 CPU sec, 2.766 real sec...
[M::process] read 719436 sequences (100000179 bp) in 1.890 CPU sec, 1.897 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 290155, 28, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 196, 549)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1327)
[M::mem_pestat] mean and std.dev: (320.27, 269.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1716)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 195, 297)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 621)
[M::mem_pestat] mean and std.dev: (225.44, 119.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 783)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 1112, 1655)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4503)
[M::mem_pestat] mean and std.dev: (927.62, 906.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5927)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 272, 1123)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3033)
[M::mem_pestat] mean and std.dev: (562.11, 611.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3988)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 720476 reads in 192.788 CPU sec, 6.188 real sec
sorting block 76, #reads = 1089707 mem = 536877606 peak = 1078034432
[M::process] read 719660 sequences (100000153 bp) in 2.027 CPU sec, 2.027 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 289972, 19, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (129, 197, 307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 663)
[M::mem_pestat] mean and std.dev: (230.42, 124.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 841)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 196, 299)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 625)
[M::mem_pestat] mean and std.dev: (226.31, 119.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 788)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (40, 764, 1370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4030)
[M::mem_pestat] mean and std.dev: (733.61, 922.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5360)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (305, 487, 708)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1514)
[M::mem_pestat] mean and std.dev: (477.64, 302.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1917)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 719808 reads in 108.168 CPU sec, 3.437 real sec
[M::mem_process_seqs] Processed 720486 reads in 276.824 CPU sec, 8.812 real sec
sorting block 77, #reads = 1088619 mem = 536881505 peak = 1078034432
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 290736, 15, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 375, 526)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1194)
[M::mem_pestat] mean and std.dev: (379.46, 224.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1528)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 196, 301)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 631)
[M::mem_pestat] mean and std.dev: (227.79, 121.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 796)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (438, 611, 1636)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4032)
[M::mem_pestat] mean and std.dev: (882.64, 898.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5230)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 239, 513)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1159)
[M::mem_pestat] mean and std.dev: (329.60, 222.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1482)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722276 sequences (100000071 bp) in 2.594 CPU sec, 2.689 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 290371, 16, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 341, 704)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1744)
[M::mem_pestat] mean and std.dev: (385.65, 357.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2264)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 196, 300)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 628)
[M::mem_pestat] mean and std.dev: (227.29, 121.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 792)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (123, 493, 1795)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5139)
[M::mem_pestat] mean and std.dev: (804.67, 1001.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6811)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 295, 1045)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2797)
[M::mem_pestat] mean and std.dev: (550.54, 667.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3673)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 728226 sequences (100000126 bp) in 2.090 CPU sec, 2.093 real sec...
[M::mem_process_seqs] Processed 719436 reads in 219.778 CPU sec, 6.982 real sec
sorting block 78, #reads = 1089658 mem = 536880742 peak = 1078034432
[M::mem_process_seqs] Processed 719660 reads in 137.257 CPU sec, 4.592 real sec
[M::process] read 725000 sequences (100000181 bp) in 2.890 CPU sec, 3.007 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 290167, 14, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 263, 744)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1868)
[M::mem_pestat] mean and std.dev: (406.85, 402.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2430)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 191, 291)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 605)
[M::mem_pestat] mean and std.dev: (220.77, 116.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 762)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (276, 773, 1113)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2787)
[M::mem_pestat] mean and std.dev: (784.86, 605.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3624)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 325, 2180)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6220)
[M::mem_pestat] mean and std.dev: (803.05, 1042.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8240)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724516 sequences (100000146 bp) in 2.273 CPU sec, 2.273 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 293198, 16, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 313, 467)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1089)
[M::mem_pestat] mean and std.dev: (301.35, 167.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1400)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 183, 275)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 565)
[M::mem_pestat] mean and std.dev: (210.09, 108.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 710)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (122, 275, 1498)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4250)
[M::mem_pestat] mean and std.dev: (918.75, 1189.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5678)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 334, 1055)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2739)
[M::mem_pestat] mean and std.dev: (495.33, 489.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3581)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 722276 reads in 218.404 CPU sec, 7.205 real sec
sorting block 79, #reads = 1087055 mem = 536882750 peak = 1078034432
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 292615, 16, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 403, 1282)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3504)
[M::mem_pestat] mean and std.dev: (576.06, 685.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4615)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 187, 282)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 582)
[M::mem_pestat] mean and std.dev: (215.30, 111.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 732)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (863, 1291, 1713)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3413)
[M::mem_pestat] mean and std.dev: (1143.19, 799.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4340)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 297, 440)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 936)
[M::mem_pestat] mean and std.dev: (249.00, 100.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1184)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 728226 reads in 222.078 CPU sec, 7.072 real sec
[M::process] read 724812 sequences (100000128 bp) in 2.533 CPU sec, 2.547 real sec...
sorting block 80, #reads = 1084736 mem = 536879093 peak = 1110687744
[M::mem_process_seqs] Processed 725000 reads in 255.714 CPU sec, 8.138 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23, 292179, 9, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (122, 177, 314)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 698)
[M::mem_pestat] mean and std.dev: (203.15, 127.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 890)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 189, 286)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 594)
[M::mem_pestat] mean and std.dev: (217.99, 113.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 748)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 379, 1022)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2620)
[M::mem_pestat] mean and std.dev: (592.09, 609.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3419)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 723660 sequences (100000049 bp) in 2.803 CPU sec, 2.898 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (22, 292394, 16, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (145, 446, 1414)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3952)
[M::mem_pestat] mean and std.dev: (511.05, 497.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5221)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 189, 286)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 594)
[M::mem_pestat] mean and std.dev: (217.73, 113.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 748)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (288, 983, 2542)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7050)
[M::mem_pestat] mean and std.dev: (1356.62, 1172.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9304)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 251, 477)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1003)
[M::mem_pestat] mean and std.dev: (294.00, 129.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1266)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723120 sequences (100000098 bp) in 2.290 CPU sec, 2.290 real sec...
[M::mem_process_seqs] Processed 724516 reads in 185.872 CPU sec, 5.883 real sec
sorting block 81, #reads = 1094659 mem = 536877925 peak = 1110687744
[M::mem_process_seqs] Processed 724812 reads in 134.680 CPU sec, 4.280 real sec
sorting block 82, #reads = 1092631 mem = 536878354 peak = 1124814848
[M::process] read 723288 sequences (100000124 bp) in 2.597 CPU sec, 2.692 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 292673, 15, 20)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 451, 3487)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10037)
[M::mem_pestat] mean and std.dev: (2194.14, 3266.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 15261)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 191, 292)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 610)
[M::mem_pestat] mean and std.dev: (221.74, 117.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 769)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (71, 407, 2063)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6047)
[M::mem_pestat] mean and std.dev: (640.62, 830.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8039)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 352, 628)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1544)
[M::mem_pestat] mean and std.dev: (382.42, 297.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2002)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723232 sequences (100000047 bp) in 1.620 CPU sec, 1.625 real sec...
[M::mem_process_seqs] Processed 723120 reads in 81.453 CPU sec, 2.560 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 292033, 24, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 254, 459)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 999)
[M::mem_pestat] mean and std.dev: (288.80, 168.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1269)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 190, 289)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 601)
[M::mem_pestat] mean and std.dev: (219.70, 115.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 757)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (364, 728, 3091)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8545)
[M::mem_pestat] mean and std.dev: (1499.83, 1518.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11272)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 495, 1471)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4051)
[M::mem_pestat] mean and std.dev: (866.67, 954.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5341)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 292489, 25, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 470, 1254)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3440)
[M::mem_pestat] mean and std.dev: (584.28, 557.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4533)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 191, 293)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 613)
[M::mem_pestat] mean and std.dev: (221.90, 118.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 773)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (595, 701, 1134)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2212)
[M::mem_pestat] mean and std.dev: (736.55, 387.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2751)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 374, 651)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1553)
[M::mem_pestat] mean and std.dev: (427.56, 316.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2004)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 723660 reads in 245.247 CPU sec, 7.754 real sec
[M::process] read 722454 sequences (100000142 bp) in 2.250 CPU sec, 2.264 real sec...
sorting block 83, #reads = 1093542 mem = 536878070 peak = 1124814848
[M::mem_process_seqs] Processed 723288 reads in 124.917 CPU sec, 4.154 real sec
sorting block 84, #reads = 1092215 mem = 536880880 peak = 1178439680
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 291752, 18, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 245, 1090)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2952)
[M::mem_pestat] mean and std.dev: (508.48, 734.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3883)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 191, 292)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 610)
[M::mem_pestat] mean and std.dev: (221.99, 117.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 769)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (72, 286, 531)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1449)
[M::mem_pestat] mean and std.dev: (398.28, 391.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1963)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 275, 1479)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4085)
[M::mem_pestat] mean and std.dev: (638.09, 734.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5388)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722008 sequences (100000023 bp) in 2.191 CPU sec, 2.271 real sec...
[M::process] read 721176 sequences (100000282 bp) in 1.610 CPU sec, 1.611 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23, 291608, 18, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 313, 500)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1164)
[M::mem_pestat] mean and std.dev: (286.05, 143.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1496)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 192, 294)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 614)
[M::mem_pestat] mean and std.dev: (223.39, 119.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 774)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 793, 879)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2295)
[M::mem_pestat] mean and std.dev: (623.38, 522.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3003)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 886, 2732)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7800)
[M::mem_pestat] mean and std.dev: (1543.93, 1691.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10334)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 723232 reads in 164.768 CPU sec, 5.424 real sec
[M::mem_process_seqs] Processed 722454 reads in 106.419 CPU sec, 3.394 real sec
sorting block 85, #reads = 1091408 mem = 536883842 peak = 1178439680
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 291504, 18, 23)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (140, 177, 393)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 899)
[M::mem_pestat] mean and std.dev: (249.56, 176.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1152)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 193, 296)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 620)
[M::mem_pestat] mean and std.dev: (224.60, 119.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 782)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (359, 1396, 2279)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6119)
[M::mem_pestat] mean and std.dev: (1278.00, 966.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8039)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 619, 1989)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5583)
[M::mem_pestat] mean and std.dev: (807.00, 872.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7380)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720896 sequences (100000264 bp) in 2.487 CPU sec, 2.525 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 291332, 15, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 258, 1455)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3981)
[M::mem_pestat] mean and std.dev: (624.04, 557.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5244)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 194, 297)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 621)
[M::mem_pestat] mean and std.dev: (225.55, 119.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 783)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (722, 1181, 2129)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4943)
[M::mem_pestat] mean and std.dev: (1315.27, 948.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6350)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (281, 370, 1036)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2546)
[M::mem_pestat] mean and std.dev: (429.68, 366.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3301)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720284 sequences (100000014 bp) in 2.168 CPU sec, 2.177 real sec...
[M::mem_process_seqs] Processed 722008 reads in 163.684 CPU sec, 5.281 real sec
sorting block 86, #reads = 1092040 mem = 536886863 peak = 1178439680
[M::mem_process_seqs] Processed 721176 reads in 115.518 CPU sec, 3.789 real sec
[M::process] read 719984 sequences (100000144 bp) in 2.243 CPU sec, 2.294 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 290435, 17, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (267, 349, 1192)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3042)
[M::mem_pestat] mean and std.dev: (682.13, 675.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3967)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 194, 297)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 621)
[M::mem_pestat] mean and std.dev: (225.59, 119.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 783)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (108, 407, 813)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2223)
[M::mem_pestat] mean and std.dev: (350.00, 264.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2928)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 330, 1176)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3186)
[M::mem_pestat] mean and std.dev: (529.84, 510.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4191)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720566 sequences (100000021 bp) in 1.668 CPU sec, 1.674 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 289735, 16, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 323, 3723)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10783)
[M::mem_pestat] mean and std.dev: (1626.52, 2030.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14313)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 195, 298)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 622)
[M::mem_pestat] mean and std.dev: (225.86, 119.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 784)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 565, 687)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1759)
[M::mem_pestat] mean and std.dev: (319.77, 258.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2295)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 516, 1066)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2828)
[M::mem_pestat] mean and std.dev: (566.52, 542.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3709)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 720896 reads in 178.433 CPU sec, 5.797 real sec
sorting block 87, #reads = 1089126 mem = 536878276 peak = 1178439680
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 290060, 20, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (242, 382, 1379)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3653)
[M::mem_pestat] mean and std.dev: (620.71, 562.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4790)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 195, 297)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 619)
[M::mem_pestat] mean and std.dev: (225.69, 119.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 780)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 436, 1068)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2818)
[M::mem_pestat] mean and std.dev: (558.78, 608.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3693)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 390, 729)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1835)
[M::mem_pestat] mean and std.dev: (403.27, 295.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2388)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720118 sequences (100000285 bp) in 2.005 CPU sec, 2.013 real sec...
[M::mem_process_seqs] Processed 719984 reads in 201.371 CPU sec, 6.391 real sec
[M::mem_process_seqs] Processed 720284 reads in 228.290 CPU sec, 7.270 real sec
sorting block 88, #reads = 1087749 mem = 536880443 peak = 1178439680
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 290373, 11, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 308, 1859)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5203)
[M::mem_pestat] mean and std.dev: (847.86, 900.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6875)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 194, 295)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 615)
[M::mem_pestat] mean and std.dev: (224.09, 118.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 775)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (417, 1687, 5924)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 16938)
[M::mem_pestat] mean and std.dev: (3140.55, 3507.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 22445)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 291, 492)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1122)
[M::mem_pestat] mean and std.dev: (359.34, 264.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1437)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720218 sequences (100000288 bp) in 2.722 CPU sec, 2.795 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 290137, 29, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (227, 666, 1104)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2858)
[M::mem_pestat] mean and std.dev: (734.75, 675.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3735)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 195, 297)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 619)
[M::mem_pestat] mean and std.dev: (225.61, 119.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 780)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 524, 2070)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5818)
[M::mem_pestat] mean and std.dev: (1012.29, 1327.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7692)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 341, 545)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1295)
[M::mem_pestat] mean and std.dev: (339.00, 253.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1670)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720284 sequences (100000034 bp) in 2.320 CPU sec, 2.318 real sec...
[M::mem_process_seqs] Processed 720566 reads in 197.802 CPU sec, 6.265 real sec
sorting block 89, #reads = 1088726 mem = 536883206 peak = 1178439680
[M::mem_process_seqs] Processed 720118 reads in 149.162 CPU sec, 4.754 real sec
sorting block 90, #reads = 1083719 mem = 536879791 peak = 1178439680
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 290799, 19, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 254, 636)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1530)
[M::mem_pestat] mean and std.dev: (345.52, 346.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1977)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 195, 296)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 616)
[M::mem_pestat] mean and std.dev: (224.92, 118.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 776)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (124, 501, 1365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3847)
[M::mem_pestat] mean and std.dev: (533.59, 523.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5088)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 390, 1505)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4129)
[M::mem_pestat] mean and std.dev: (761.65, 844.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5441)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720602 sequences (100000283 bp) in 3.007 CPU sec, 3.142 real sec...
[M::process] read 728816 sequences (100000142 bp) in 2.462 CPU sec, 2.473 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 290293, 12, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 314, 1041)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2661)
[M::mem_pestat] mean and std.dev: (575.38, 476.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3471)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 195, 297)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 619)
[M::mem_pestat] mean and std.dev: (225.41, 119.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 780)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (237, 544, 721)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1689)
[M::mem_pestat] mean and std.dev: (430.00, 335.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2173)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (278, 662, 821)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1907)
[M::mem_pestat] mean and std.dev: (593.38, 377.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2450)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 720218 reads in 218.514 CPU sec, 7.232 real sec
[M::process] read 729854 sequences (100000120 bp) in 2.585 CPU sec, 2.593 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 290072, 29, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 267, 756)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1932)
[M::mem_pestat] mean and std.dev: (423.83, 414.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2520)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 194, 296)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 618)
[M::mem_pestat] mean and std.dev: (224.83, 119.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 779)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (134, 607, 1665)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4727)
[M::mem_pestat] mean and std.dev: (910.38, 915.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6258)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 884, 1775)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4939)
[M::mem_pestat] mean and std.dev: (973.19, 983.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6521)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 720602 reads in 134.254 CPU sec, 4.386 real sec
sorting block 91, #reads = 1087617 mem = 536880018 peak = 1178439680
[M::mem_process_seqs] Processed 720284 reads in 335.575 CPU sec, 10.832 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 293059, 16, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 465, 1161)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3041)
[M::mem_pestat] mean and std.dev: (648.36, 542.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3981)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 181, 269)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 549)
[M::mem_pestat] mean and std.dev: (206.05, 103.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 689)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (676, 1034, 1392)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2824)
[M::mem_pestat] mean and std.dev: (1022.69, 622.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3540)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 347, 652)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1532)
[M::mem_pestat] mean and std.dev: (390.87, 348.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1972)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 92, #reads = 1083411 mem = 536887327 peak = 1178439680
[M::process] read 728696 sequences (100000073 bp) in 2.527 CPU sec, 2.855 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 294418, 9, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (113, 160, 446)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1112)
[M::mem_pestat] mean and std.dev: (196.38, 137.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1445)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 180, 267)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 543)
[M::mem_pestat] mean and std.dev: (205.06, 103.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 681)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 222, 1036)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2752)
[M::mem_pestat] mean and std.dev: (521.85, 539.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3610)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 727754 sequences (100000209 bp) in 2.219 CPU sec, 2.216 real sec...
[M::mem_process_seqs] Processed 728816 reads in 255.697 CPU sec, 8.142 real sec
[M::mem_process_seqs] Processed 729854 reads in 149.993 CPU sec, 4.751 real sec
sorting block 93, #reads = 1084239 mem = 536882391 peak = 1178439680
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 293495, 12, 14)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 408, 1499)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4073)
[M::mem_pestat] mean and std.dev: (589.58, 599.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5360)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 182, 273)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 561)
[M::mem_pestat] mean and std.dev: (209.18, 107.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 705)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (331, 964, 1636)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4246)
[M::mem_pestat] mean and std.dev: (947.33, 749.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5551)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 328, 781)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1913)
[M::mem_pestat] mean and std.dev: (433.85, 296.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2479)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 729378 sequences (100000136 bp) in 3.158 CPU sec, 3.265 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 293388, 8, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 283, 445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 949)
[M::mem_pestat] mean and std.dev: (248.35, 113.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1201)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 184, 274)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 562)
[M::mem_pestat] mean and std.dev: (209.94, 107.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 706)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 333, 732)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1782)
[M::mem_pestat] mean and std.dev: (404.27, 303.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2307)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 726964 sequences (100000284 bp) in 2.340 CPU sec, 2.343 real sec...
[M::mem_process_seqs] Processed 728696 reads in 202.758 CPU sec, 6.411 real sec
[M::mem_process_seqs] Processed 727754 reads in 139.057 CPU sec, 4.401 real sec
sorting block 94, #reads = 1093304 mem = 536881503 peak = 1178439680
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 294025, 7, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 316, 520)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1146)
[M::mem_pestat] mean and std.dev: (323.67, 200.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1459)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 181, 270)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 552)
[M::mem_pestat] mean and std.dev: (206.96, 105.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 693)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (264, 407, 634)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1374)
[M::mem_pestat] mean and std.dev: (395.68, 194.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1744)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 727064 sequences (100000011 bp) in 2.785 CPU sec, 2.874 real sec...
[M::process] read 725002 sequences (100000244 bp) in 2.010 CPU sec, 2.010 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 293093, 16, 16)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (225, 368, 1969)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5457)
[M::mem_pestat] mean and std.dev: (918.88, 1028.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7201)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 185, 277)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 569)
[M::mem_pestat] mean and std.dev: (211.64, 108.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 715)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (501, 694, 965)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1893)
[M::mem_pestat] mean and std.dev: (521.00, 255.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2357)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 365, 1091)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2879)
[M::mem_pestat] mean and std.dev: (506.93, 476.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3773)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 729378 reads in 210.425 CPU sec, 6.686 real sec
sorting block 95, #reads = 1092790 mem = 536882248 peak = 1178439680
[M::mem_process_seqs] Processed 726964 reads in 145.655 CPU sec, 4.924 real sec
sorting block 96, #reads = 1088946 mem = 536883114 peak = 1178439680
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 293052, 21, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (116, 196, 357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 839)
[M::mem_pestat] mean and std.dev: (176.95, 78.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1080)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 183, 275)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 565)
[M::mem_pestat] mean and std.dev: (210.25, 107.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 710)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (261, 684, 2984)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8430)
[M::mem_pestat] mean and std.dev: (1794.14, 2276.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11153)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 432, 1089)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2865)
[M::mem_pestat] mean and std.dev: (645.64, 527.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3753)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724296 sequences (100000242 bp) in 2.858 CPU sec, 2.948 real sec...
[M::process] read 723318 sequences (100000164 bp) in 2.380 CPU sec, 2.385 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 292685, 14, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 227, 492)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1156)
[M::mem_pestat] mean and std.dev: (301.31, 222.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1488)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 187, 283)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 585)
[M::mem_pestat] mean and std.dev: (215.87, 112.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 736)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (59, 621, 3768)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 11186)
[M::mem_pestat] mean and std.dev: (2081.64, 2919.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14895)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 242, 595)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1363)
[M::mem_pestat] mean and std.dev: (327.11, 259.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1747)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 727064 reads in 216.312 CPU sec, 7.131 real sec
[M::mem_process_seqs] Processed 725002 reads in 148.756 CPU sec, 4.732 real sec
sorting block 97, #reads = 1091131 mem = 536879951 peak = 1178439680
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 292058, 11, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (488, 652, 1679)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4061)
[M::mem_pestat] mean and std.dev: (897.00, 626.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5252)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 188, 286)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 594)
[M::mem_pestat] mean and std.dev: (217.88, 114.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 748)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (67, 327, 1713)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5005)
[M::mem_pestat] mean and std.dev: (646.80, 696.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6651)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 324, 836)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2116)
[M::mem_pestat] mean and std.dev: (515.86, 449.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2756)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 721844 sequences (100000298 bp) in 3.029 CPU sec, 3.109 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 291825, 22, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 351, 586)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1428)
[M::mem_pestat] mean and std.dev: (359.26, 229.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1849)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 190, 288)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 598)
[M::mem_pestat] mean and std.dev: (219.47, 115.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 753)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (96, 313, 509)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1335)
[M::mem_pestat] mean and std.dev: (302.35, 272.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1748)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (265, 329, 370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (55, 580)
[M::mem_pestat] mean and std.dev: (310.44, 113.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 766)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 721266 sequences (100000237 bp) in 2.370 CPU sec, 2.366 real sec...
[M::mem_process_seqs] Processed 724296 reads in 207.904 CPU sec, 6.591 real sec
sorting block 98, #reads = 1090560 mem = 536877711 peak = 1178439680
[M::mem_process_seqs] Processed 723318 reads in 145.717 CPU sec, 4.717 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 291155, 22, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 243, 1462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4092)
[M::mem_pestat] mean and std.dev: (607.20, 680.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5407)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 191, 291)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 605)
[M::mem_pestat] mean and std.dev: (221.55, 116.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 762)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (374, 796, 1353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3311)
[M::mem_pestat] mean and std.dev: (804.75, 583.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4290)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 212, 965)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2541)
[M::mem_pestat] mean and std.dev: (406.10, 374.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3329)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720856 sequences (100000037 bp) in 3.054 CPU sec, 3.136 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 290957, 23, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 238, 939)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2475)
[M::mem_pestat] mean and std.dev: (457.23, 436.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3243)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 193, 293)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 609)
[M::mem_pestat] mean and std.dev: (223.10, 117.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 767)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (134, 714, 1334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3734)
[M::mem_pestat] mean and std.dev: (978.61, 1022.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5068)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 428, 941)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2441)
[M::mem_pestat] mean and std.dev: (526.75, 364.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3191)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720670 sequences (100000063 bp) in 2.480 CPU sec, 2.477 real sec...
[M::mem_process_seqs] Processed 721844 reads in 212.523 CPU sec, 6.967 real sec
sorting block 99, #reads = 1089089 mem = 536879386 peak = 1178439680
[M::mem_process_seqs] Processed 721266 reads in 146.157 CPU sec, 4.662 real sec
sorting block 100, #reads = 1087777 mem = 536878100 peak = 1178439680
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23, 290460, 21, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (225, 305, 469)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 957)
[M::mem_pestat] mean and std.dev: (279.42, 133.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1201)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 193, 294)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 612)
[M::mem_pestat] mean and std.dev: (223.15, 117.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 771)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (302, 800, 1379)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3533)
[M::mem_pestat] mean and std.dev: (656.78, 461.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4610)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 264, 558)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1294)
[M::mem_pestat] mean and std.dev: (369.76, 290.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1662)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 719512 sequences (100000057 bp) in 2.987 CPU sec, 3.078 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 290342, 19, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 278, 705)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1789)
[M::mem_pestat] mean and std.dev: (346.90, 294.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2331)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 193, 295)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 615)
[M::mem_pestat] mean and std.dev: (224.10, 118.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 775)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (365, 688, 2567)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6971)
[M::mem_pestat] mean and std.dev: (1343.44, 1664.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9173)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (284, 322, 465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 827)
[M::mem_pestat] mean and std.dev: (307.69, 118.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1008)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 718982 sequences (100000250 bp) in 2.216 CPU sec, 2.217 real sec...
[M::mem_process_seqs] Processed 720856 reads in 208.916 CPU sec, 6.662 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 290205, 25, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 334, 838)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2136)
[M::mem_pestat] mean and std.dev: (442.38, 421.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2785)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 196, 297)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 619)
[M::mem_pestat] mean and std.dev: (225.84, 118.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 780)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (452, 1418, 3841)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10619)
[M::mem_pestat] mean and std.dev: (1822.20, 1677.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14008)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (231, 456, 792)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1914)
[M::mem_pestat] mean and std.dev: (403.52, 215.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2475)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 718680 sequences (100000105 bp) in 2.571 CPU sec, 2.585 real sec...
[M::mem_process_seqs] Processed 719512 reads in 123.097 CPU sec, 3.907 real sec
sorting block 101, #reads = 1088081 mem = 536880315 peak = 1178439680
[M::mem_process_seqs] Processed 720670 reads in 311.226 CPU sec, 9.922 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 290170, 26, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 245, 350)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 696)
[M::mem_pestat] mean and std.dev: (248.10, 108.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 869)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 197, 300)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 626)
[M::mem_pestat] mean and std.dev: (227.65, 120.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 789)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (485, 658, 1478)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3464)
[M::mem_pestat] mean and std.dev: (889.62, 603.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4457)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 457, 1481)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3985)
[M::mem_pestat] mean and std.dev: (638.68, 512.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5237)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 102, #reads = 1089025 mem = 536880423 peak = 1178439680
[M::process] read 718808 sequences (100000219 bp) in 2.961 CPU sec, 3.152 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 290045, 12, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 283, 357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 653)
[M::mem_pestat] mean and std.dev: (251.63, 95.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 801)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 198, 302)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 632)
[M::mem_pestat] mean and std.dev: (229.20, 121.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 797)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 284, 1620)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4464)
[M::mem_pestat] mean and std.dev: (649.33, 686.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5886)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 223, 675)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1735)
[M::mem_pestat] mean and std.dev: (369.00, 310.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2265)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 718982 reads in 233.457 CPU sec, 7.438 real sec
[M::mem_process_seqs] Processed 718680 reads in 146.185 CPU sec, 4.626 real sec
[M::process] read 687986 sequences (95540574 bp) in 2.645 CPU sec, 2.727 real sec...
sorting block 103, #reads = 1087983 mem = 536883649 peak = 1178439680
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 289979, 21, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 227, 428)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 934)
[M::mem_pestat] mean and std.dev: (259.48, 146.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1187)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 198, 302)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 632)
[M::mem_pestat] mean and std.dev: (229.07, 121.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 797)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (397, 617, 1521)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3769)
[M::mem_pestat] mean and std.dev: (783.67, 795.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4893)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 353, 573)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1353)
[M::mem_pestat] mean and std.dev: (395.55, 291.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1743)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 277125, 15, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 281, 438)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 976)
[M::mem_pestat] mean and std.dev: (281.91, 166.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1245)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 196, 299)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 625)
[M::mem_pestat] mean and std.dev: (226.56, 120.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 788)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (667, 1008, 4396)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 11854)
[M::mem_pestat] mean and std.dev: (2512.00, 2249.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 15583)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 284, 468)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1060)
[M::mem_pestat] mean and std.dev: (251.50, 145.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1356)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 718808 reads in 198.257 CPU sec, 6.430 real sec
sorting block 104, #reads = 1087802 mem = 536881724 peak = 1178439680
[M::mem_process_seqs] Processed 687986 reads in 140.135 CPU sec, 4.546 real sec
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000c06f2
  features: bfebfbff 7ffefbff
  extended: f3bfb7ef fb417ffe
  amd bits: 2c100800 00000121
     brand: INTEL(R) XEON(R) PLATINUM 8559C
threads: 31
algo: bwa-mem
license: sentieon:klib=31
reads: 114608088
overall: 70518468608 mem 18315.471 user 344.234 sys 615.440 real
[main] Version: 0.7.17-r1188
[main] CMD: /opt/conda/share/sentieon-202308.03-3/libexec/bwa mem -K 100000000 -Y -R @RG\tID:A23MHWWLT4.1136_8DV-T1-TDNA-1_A23MHWWLT4_1.L002\tPU:L002\tSM:1136_8DV-T1-TDNA-1_A23MHWWLT4_1\tLB:1136_8DV-T1-TDNA-1_A23MHWWLT4_1\tDS:s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta\tPL:ILLUMINA -t 31 ./BWAIndex/Homo_sapiens_assembly38.fasta.64 1136_8DV-T1-TDNA-1_A23MHWWLT4_1_R1.fastq.gz 1136_8DV-T1-TDNA-1_A23MHWWLT4_1_R2.fastq.gz
[main] Real time: 615.480 sec; CPU: 18659.708 sec
sorting block 105, #reads = 955401 mem = 472122550 peak = 1178439680
uniq header count 1
merging 106 blocks
sw version: sentieon-genomics-202308.03
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000c06f2
  features: bfebfbff 7ffefbff
  extended: f3bfb7ef fb417ffe
  amd bits: 2c100800 00000121
     brand: INTEL(R) XEON(R) PLATINUM 8559C
threads: 31 max 192
algo: util-sort
license: sentieon:util=1
output file size: 6198140197
output reads: 115452901
bam_mem_sort: 106 calls 59.251 user 0.882 sys 60.266 real
bam_write: 106 calls 34.156 user 1.875 sys 37.018 real
execute: 1 calls 40.547 user 1.395 sys 666.131 real
merge_files: 1 calls 40.507 user 1.374 sys 49.992 real
parse_chunk: 1695 calls 99.684 user 22.088 sys 123.279 real
read_chunk: 4593 calls 53.500 user 33.792 sys 573.671 real
sort_block: 1 calls 32.918 user 33.184 sys 545.258 real
write_chunk: 2896 calls 39.937 user 0.817 sys 48.467 real
overall: 3450425344 mem 1886.216 user 74.994 sys 666.158 real
ls: cannot access '*.cram': No such file or directory