cmdline: /opt/conda/share/sentieon-202308.03-3/libexec/util sort -r Homo_sapiens_assembly38.fasta -t 31 -o 1136_3LU-T1-TDNA-1_A23MHWWLT4_1.bam --sam2bam -
This software is licensed to bgold@natera.com by Sentieon Inc.
This software is licensed to bgold@natera.com by Sentieon Inc.
version: sentieon-genomics-202308.03
[M::bwa_idx_load_from_disk] read 3171 ALT contigs
[M::main_mem] bwa index loaded in 1992.208 CPU sec, 70.065 real sec
[M::process] read 681452 sequences (100000048 bp) in 1.314 CPU sec, 1.322 real sec...
[M::process] read 680684 sequences (100000078 bp) in 1.626 CPU sec, 1.687 real sec...
[M::process] read 680238 sequences (100000126 bp) in 1.595 CPU sec, 1.596 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (17, 283573, 4, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (260, 305, 535)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1085)
[M::mem_pestat] mean and std.dev: (326.25, 138.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1360)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 354, 492)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1028)
[M::mem_pestat] mean and std.dev: (367.84, 176.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1296)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 330, 506)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1158)
[M::mem_pestat] mean and std.dev: (351.62, 210.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1484)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 679928 sequences (100000278 bp) in 1.533 CPU sec, 1.568 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 282658, 2, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 372, 558)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1250)
[M::mem_pestat] mean and std.dev: (345.62, 152.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1596)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (231, 362, 498)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1032)
[M::mem_pestat] mean and std.dev: (373.96, 176.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1299)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (264, 362, 531)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1065)
[M::mem_pestat] mean and std.dev: (406.94, 203.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1332)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 282528, 2, 24)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (142, 191, 283)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 565)
[M::mem_pestat] mean and std.dev: (199.84, 96.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 706)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 361, 498)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1036)
[M::mem_pestat] mean and std.dev: (373.23, 177.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1305)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 282, 379)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 739)
[M::mem_pestat] mean and std.dev: (277.87, 111.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 919)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681452 reads in 280.054 CPU sec, 9.083 real sec
[M::mem_process_seqs] Processed 680238 reads in 186.283 CPU sec, 6.097 real sec
[M::mem_process_seqs] Processed 680684 reads in 202.437 CPU sec, 6.620 real sec
sorting block 0, #reads = 1081873 mem = 536880169 peak = 602906624
[M::process] read 679596 sequences (100000011 bp) in 2.201 CPU sec, 2.362 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 282178, 4, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 214, 448)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 940)
[M::mem_pestat] mean and std.dev: (267.97, 138.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1186)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (233, 364, 501)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1037)
[M::mem_pestat] mean and std.dev: (376.16, 177.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1305)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 334, 442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 892)
[M::mem_pestat] mean and std.dev: (327.24, 125.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1117)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 679178 sequences (100000033 bp) in 1.754 CPU sec, 1.792 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (21, 283038, 6, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (300, 305, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (224, 414)
[M::mem_pestat] mean and std.dev: (310.33, 14.23)
[M::mem_pestat] low and high boundaries for proper pairs: (186, 452)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (236, 368, 503)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1037)
[M::mem_pestat] mean and std.dev: (378.94, 177.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1304)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (234, 291, 522)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1098)
[M::mem_pestat] mean and std.dev: (355.22, 165.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1386)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 678882 sequences (100000210 bp) in 1.625 CPU sec, 1.629 real sec...
[M::mem_process_seqs] Processed 679928 reads in 172.404 CPU sec, 5.471 real sec
sorting block 1, #reads = 1081748 mem = 536880205 peak = 920625152
[M::mem_process_seqs] Processed 679596 reads in 110.417 CPU sec, 3.489 real sec
sorting block 2, #reads = 1080456 mem = 536877532 peak = 960651264
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 281888, 0, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (139, 210, 227)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 403)
[M::mem_pestat] mean and std.dev: (184.85, 53.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 491)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (237, 371, 509)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1053)
[M::mem_pestat] mean and std.dev: (381.59, 178.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1325)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (268, 289, 611)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1297)
[M::mem_pestat] mean and std.dev: (323.82, 175.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1640)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 678554 sequences (100000088 bp) in 2.017 CPU sec, 2.147 real sec...
[M::process] read 678344 sequences (100000106 bp) in 1.558 CPU sec, 1.563 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 281649, 0, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 186, 318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 648)
[M::mem_pestat] mean and std.dev: (206.71, 96.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 813)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (240, 371, 506)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1038)
[M::mem_pestat] mean and std.dev: (381.05, 176.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1304)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 219, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 542)
[M::mem_pestat] mean and std.dev: (203.27, 65.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 651)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 679178 reads in 174.128 CPU sec, 5.567 real sec
[M::mem_process_seqs] Processed 678882 reads in 111.248 CPU sec, 3.580 real sec
sorting block 3, #reads = 1079971 mem = 536884763 peak = 960651264
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 282225, 1, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (246, 368, 389)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 675)
[M::mem_pestat] mean and std.dev: (323.60, 97.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 818)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (242, 375, 508)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1040)
[M::mem_pestat] mean and std.dev: (383.54, 176.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1306)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (255, 359, 493)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 969)
[M::mem_pestat] mean and std.dev: (366.02, 181.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1207)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 677644 sequences (100000265 bp) in 2.220 CPU sec, 2.630 real sec...
[M::process] read 677414 sequences (100000266 bp) in 1.765 CPU sec, 1.772 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 282474, 2, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 255, 400)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 904)
[M::mem_pestat] mean and std.dev: (271.65, 205.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1156)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (243, 378, 512)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1050)
[M::mem_pestat] mean and std.dev: (385.73, 177.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1319)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (238, 336, 520)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1084)
[M::mem_pestat] mean and std.dev: (356.83, 140.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1366)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 678554 reads in 173.507 CPU sec, 5.605 real sec
[M::mem_process_seqs] Processed 678344 reads in 112.285 CPU sec, 3.589 real sec
sorting block 4, #reads = 1079822 mem = 536878973 peak = 960651264
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 281850, 6, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (138, 272, 464)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1116)
[M::mem_pestat] mean and std.dev: (309.73, 203.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1442)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (247, 382, 517)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1057)
[M::mem_pestat] mean and std.dev: (390.59, 178.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1327)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (238, 311, 413)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 763)
[M::mem_pestat] mean and std.dev: (309.82, 105.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 938)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 677770 sequences (100000126 bp) in 2.098 CPU sec, 2.325 real sec...
[M::process] read 677492 sequences (100000170 bp) in 1.637 CPU sec, 1.653 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 281160, 1, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 194, 315)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 623)
[M::mem_pestat] mean and std.dev: (212.00, 91.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 777)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (250, 386, 522)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1066)
[M::mem_pestat] mean and std.dev: (393.95, 179.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1338)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 276, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 670)
[M::mem_pestat] mean and std.dev: (231.29, 92.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 844)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 677644 reads in 175.665 CPU sec, 5.640 real sec
sorting block 5, #reads = 1078994 mem = 536879310 peak = 960651264
[M::mem_process_seqs] Processed 677414 reads in 114.566 CPU sec, 3.662 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (22, 281410, 3, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 182, 415)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 931)
[M::mem_pestat] mean and std.dev: (242.68, 115.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1189)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (247, 381, 516)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1054)
[M::mem_pestat] mean and std.dev: (389.31, 178.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1323)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 275, 454)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 988)
[M::mem_pestat] mean and std.dev: (299.45, 142.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1255)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 677364 sequences (100000228 bp) in 2.475 CPU sec, 2.736 real sec...
[M::process] read 677474 sequences (100000135 bp) in 1.790 CPU sec, 1.798 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 281866, 0, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 278, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 571)
[M::mem_pestat] mean and std.dev: (263.14, 109.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 702)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (249, 383, 518)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1056)
[M::mem_pestat] mean and std.dev: (391.10, 178.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1325)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (250, 384, 473)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 919)
[M::mem_pestat] mean and std.dev: (331.40, 126.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1142)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 677770 reads in 179.294 CPU sec, 5.732 real sec
sorting block 6, #reads = 1079071 mem = 536878066 peak = 960651264
[M::mem_process_seqs] Processed 677492 reads in 114.283 CPU sec, 3.656 real sec
sorting block 7, #reads = 1079067 mem = 536878148 peak = 960651264
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 281485, 3, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 260, 521)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1149)
[M::mem_pestat] mean and std.dev: (300.14, 167.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1463)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (248, 382, 517)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1055)
[M::mem_pestat] mean and std.dev: (390.49, 178.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1324)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (344, 375, 455)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (122, 677)
[M::mem_pestat] mean and std.dev: (370.53, 99.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 788)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 677342 sequences (100000151 bp) in 2.290 CPU sec, 2.459 real sec...
[M::process] read 677918 sequences (100000121 bp) in 1.821 CPU sec, 1.821 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 281395, 3, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 321, 487)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1087)
[M::mem_pestat] mean and std.dev: (310.50, 138.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1387)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (247, 382, 517)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1057)
[M::mem_pestat] mean and std.dev: (390.45, 179.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1327)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (286, 324, 472)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 844)
[M::mem_pestat] mean and std.dev: (355.96, 150.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1030)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 677364 reads in 183.741 CPU sec, 5.907 real sec
[M::mem_process_seqs] Processed 677474 reads in 116.072 CPU sec, 3.712 real sec
sorting block 8, #reads = 1078877 mem = 536881025 peak = 960651264
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 280752, 7, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 277, 503)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1061)
[M::mem_pestat] mean and std.dev: (298.02, 125.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1340)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (249, 387, 525)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1077)
[M::mem_pestat] mean and std.dev: (395.73, 182.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1353)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 332, 347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 593)
[M::mem_pestat] mean and std.dev: (296.44, 105.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 719)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 677190 sequences (100000127 bp) in 2.492 CPU sec, 2.891 real sec...
[M::process] read 677042 sequences (100000088 bp) in 1.828 CPU sec, 1.830 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 281259, 3, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 370, 477)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1077)
[M::mem_pestat] mean and std.dev: (354.21, 204.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1377)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (243, 375, 512)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1050)
[M::mem_pestat] mean and std.dev: (386.43, 179.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1319)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 340, 467)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1049)
[M::mem_pestat] mean and std.dev: (313.25, 161.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1340)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 677342 reads in 184.837 CPU sec, 5.922 real sec
[M::mem_process_seqs] Processed 677918 reads in 117.047 CPU sec, 3.727 real sec
sorting block 9, #reads = 1078340 mem = 536877016 peak = 960651264
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 280721, 4, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 312, 434)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 870)
[M::mem_pestat] mean and std.dev: (324.71, 143.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1088)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (251, 384, 519)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1055)
[M::mem_pestat] mean and std.dev: (392.41, 178.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1323)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 271, 375)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 711)
[M::mem_pestat] mean and std.dev: (261.87, 115.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 879)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 677132 sequences (100000249 bp) in 2.105 CPU sec, 2.518 real sec...
[M::process] read 677070 sequences (100000089 bp) in 1.880 CPU sec, 1.885 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 281322, 8, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (265, 761, 761)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1753)
[M::mem_pestat] mean and std.dev: (521.34, 252.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2249)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (252, 387, 524)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1068)
[M::mem_pestat] mean and std.dev: (395.52, 180.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1340)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 386, 500)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1068)
[M::mem_pestat] mean and std.dev: (339.20, 130.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1352)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 677190 reads in 182.958 CPU sec, 5.889 real sec
sorting block 10, #reads = 1077966 mem = 536877655 peak = 960651264
[M::mem_process_seqs] Processed 677042 reads in 115.782 CPU sec, 3.705 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 280927, 0, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 305, 413)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 915)
[M::mem_pestat] mean and std.dev: (254.78, 109.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1166)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (249, 379, 513)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1041)
[M::mem_pestat] mean and std.dev: (388.55, 176.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1305)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 290, 497)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1087)
[M::mem_pestat] mean and std.dev: (303.50, 166.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1382)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 11, #reads = 1077357 mem = 536880951 peak = 960651264
[M::process] read 677284 sequences (100000251 bp) in 2.528 CPU sec, 2.840 real sec...
[M::process] read 677314 sequences (100000119 bp) in 1.885 CPU sec, 1.895 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 280646, 3, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 381, 595)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1425)
[M::mem_pestat] mean and std.dev: (348.30, 221.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1840)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (250, 381, 514)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1042)
[M::mem_pestat] mean and std.dev: (389.59, 176.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1306)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 251, 378)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 746)
[M::mem_pestat] mean and std.dev: (269.51, 122.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 930)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 677132 reads in 186.632 CPU sec, 5.986 real sec
[M::mem_process_seqs] Processed 677070 reads in 120.689 CPU sec, 3.839 real sec
sorting block 12, #reads = 1078160 mem = 536879058 peak = 960651264
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 281223, 8, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 247, 492)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1082)
[M::mem_pestat] mean and std.dev: (304.26, 158.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1377)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (247, 376, 509)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1033)
[M::mem_pestat] mean and std.dev: (385.80, 175.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1295)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 311, 506)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1142)
[M::mem_pestat] mean and std.dev: (350.09, 220.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1460)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 677098 sequences (100000142 bp) in 2.381 CPU sec, 2.628 real sec...
[M::process] read 677000 sequences (100000003 bp) in 1.882 CPU sec, 1.889 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 279763, 0, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (268, 295, 528)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1048)
[M::mem_pestat] mean and std.dev: (300.10, 93.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1308)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (247, 376, 509)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1033)
[M::mem_pestat] mean and std.dev: (385.81, 174.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1295)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (254, 283, 408)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 716)
[M::mem_pestat] mean and std.dev: (314.12, 129.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 870)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 677284 reads in 189.980 CPU sec, 6.083 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 281197, 4, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 361, 419)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 839)
[M::mem_pestat] mean and std.dev: (330.00, 169.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1049)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (249, 377, 510)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1032)
[M::mem_pestat] mean and std.dev: (386.29, 174.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1293)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (243, 408, 789)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1881)
[M::mem_pestat] mean and std.dev: (395.42, 259.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2427)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 677532 sequences (100000017 bp) in 2.104 CPU sec, 2.111 real sec...
[M::mem_process_seqs] Processed 677098 reads in 106.208 CPU sec, 3.581 real sec
sorting block 13, #reads = 1078976 mem = 536878740 peak = 960651264
[M::mem_process_seqs] Processed 677314 reads in 279.246 CPU sec, 9.154 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 280671, 1, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (226, 368, 514)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1090)
[M::mem_pestat] mean and std.dev: (342.85, 158.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1378)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (249, 380, 513)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1041)
[M::mem_pestat] mean and std.dev: (388.80, 175.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1305)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (277, 402, 555)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1111)
[M::mem_pestat] mean and std.dev: (385.04, 139.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1389)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 14, #reads = 1077253 mem = 536879393 peak = 960651264
[M::process] read 677556 sequences (100000102 bp) in 2.275 CPU sec, 2.508 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 280813, 1, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (225, 278, 417)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 801)
[M::mem_pestat] mean and std.dev: (305.58, 125.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 993)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 372, 506)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1030)
[M::mem_pestat] mean and std.dev: (382.87, 174.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1292)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 282, 449)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1007)
[M::mem_pestat] mean and std.dev: (259.97, 144.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1286)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 677000 reads in 205.986 CPU sec, 6.633 real sec
[M::process] read 677352 sequences (100000218 bp) in 2.027 CPU sec, 2.071 real sec...
[M::mem_process_seqs] Processed 677532 reads in 122.514 CPU sec, 3.903 real sec
sorting block 15, #reads = 1076760 mem = 536883718 peak = 960651264
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 281081, 1, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (136, 219, 265)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 523)
[M::mem_pestat] mean and std.dev: (212.86, 102.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 652)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (245, 376, 510)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1040)
[M::mem_pestat] mean and std.dev: (385.49, 176.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1305)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 269, 418)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 840)
[M::mem_pestat] mean and std.dev: (298.56, 162.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1051)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 677222 sequences (100000057 bp) in 2.549 CPU sec, 2.803 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 281781, 0, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 276, 308)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 538)
[M::mem_pestat] mean and std.dev: (259.68, 83.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 653)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (246, 376, 511)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1041)
[M::mem_pestat] mean and std.dev: (385.97, 175.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1306)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 556, 650)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1522)
[M::mem_pestat] mean and std.dev: (443.11, 216.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1958)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 677314 sequences (100000069 bp) in 1.834 CPU sec, 1.840 real sec...
[M::mem_process_seqs] Processed 677556 reads in 185.041 CPU sec, 5.918 real sec
[M::mem_process_seqs] Processed 677352 reads in 119.554 CPU sec, 3.804 real sec
sorting block 16, #reads = 1077561 mem = 536878610 peak = 960651264
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 281610, 1, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (138, 237, 312)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 660)
[M::mem_pestat] mean and std.dev: (241.55, 130.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 834)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (247, 378, 512)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1042)
[M::mem_pestat] mean and std.dev: (387.21, 176.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1307)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 340, 447)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 935)
[M::mem_pestat] mean and std.dev: (303.33, 135.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1179)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 677306 sequences (100000163 bp) in 2.366 CPU sec, 2.669 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 280765, 8, 23)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 258, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 651)
[M::mem_pestat] mean and std.dev: (262.84, 137.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 815)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (246, 377, 512)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1044)
[M::mem_pestat] mean and std.dev: (387.12, 177.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1310)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 359, 505)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1081)
[M::mem_pestat] mean and std.dev: (306.16, 135.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1369)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 676990 sequences (100000215 bp) in 1.945 CPU sec, 1.993 real sec...
[M::mem_process_seqs] Processed 677222 reads in 183.237 CPU sec, 5.874 real sec
[M::mem_process_seqs] Processed 677314 reads in 117.437 CPU sec, 3.731 real sec
sorting block 17, #reads = 1077545 mem = 536879375 peak = 960651264
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 281169, 5, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 268, 475)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1001)
[M::mem_pestat] mean and std.dev: (261.32, 116.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1264)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (248, 380, 515)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1049)
[M::mem_pestat] mean and std.dev: (389.47, 178.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1316)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (236, 300, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (20, 560)
[M::mem_pestat] mean and std.dev: (288.33, 90.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 668)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 676478 sequences (100000190 bp) in 2.628 CPU sec, 2.917 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 281092, 4, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 300, 402)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 838)
[M::mem_pestat] mean and std.dev: (307.18, 163.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1056)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (249, 384, 522)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1068)
[M::mem_pestat] mean and std.dev: (393.90, 180.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1341)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 319, 416)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 798)
[M::mem_pestat] mean and std.dev: (315.86, 131.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 989)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 676578 sequences (100000230 bp) in 2.024 CPU sec, 2.027 real sec...
[M::mem_process_seqs] Processed 677306 reads in 182.450 CPU sec, 5.841 real sec
sorting block 18, #reads = 1077552 mem = 536879400 peak = 960651264
[M::mem_process_seqs] Processed 676990 reads in 117.664 CPU sec, 3.753 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 281555, 2, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 261, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 663)
[M::mem_pestat] mean and std.dev: (272.65, 93.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 812)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (253, 389, 527)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1075)
[M::mem_pestat] mean and std.dev: (398.56, 182.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1349)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (234, 323, 591)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1305)
[M::mem_pestat] mean and std.dev: (391.59, 219.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1662)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 19, #reads = 1077181 mem = 536881374 peak = 985853952
[M::process] read 679692 sequences (100000246 bp) in 2.637 CPU sec, 3.099 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 281657, 1, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (120, 175, 521)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1323)
[M::mem_pestat] mean and std.dev: (271.50, 243.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1724)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (254, 389, 527)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1073)
[M::mem_pestat] mean and std.dev: (398.75, 183.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1346)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 275, 355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 765)
[M::mem_pestat] mean and std.dev: (275.30, 133.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 970)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 676478 reads in 178.021 CPU sec, 5.761 real sec
[M::process] read 680536 sequences (100000290 bp) in 1.998 CPU sec, 2.037 real sec...
[M::mem_process_seqs] Processed 676578 reads in 114.692 CPU sec, 3.680 real sec
sorting block 20, #reads = 1077419 mem = 536885774 peak = 985853952
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 282909, 7, 21)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 295, 430)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 908)
[M::mem_pestat] mean and std.dev: (311.51, 153.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1147)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (234, 366, 505)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1047)
[M::mem_pestat] mean and std.dev: (379.22, 179.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1318)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 206, 450)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1036)
[M::mem_pestat] mean and std.dev: (262.53, 177.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1329)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 679926 sequences (100000162 bp) in 2.668 CPU sec, 3.040 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 282441, 2, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (235, 377, 402)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 736)
[M::mem_pestat] mean and std.dev: (318.35, 140.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 903)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 358, 496)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1032)
[M::mem_pestat] mean and std.dev: (371.98, 177.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1300)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (249, 291, 454)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 864)
[M::mem_pestat] mean and std.dev: (336.53, 163.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1069)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 679406 sequences (100000130 bp) in 1.692 CPU sec, 1.693 real sec...
[M::mem_process_seqs] Processed 679692 reads in 180.630 CPU sec, 5.812 real sec
[M::mem_process_seqs] Processed 680536 reads in 115.863 CPU sec, 3.693 real sec
sorting block 21, #reads = 1078598 mem = 536878674 peak = 985853952
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 282015, 2, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 256, 385)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 837)
[M::mem_pestat] mean and std.dev: (263.08, 119.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1063)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (233, 362, 498)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1028)
[M::mem_pestat] mean and std.dev: (375.05, 177.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1293)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 442, 659)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1543)
[M::mem_pestat] mean and std.dev: (338.48, 167.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1985)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 679208 sequences (100000147 bp) in 2.456 CPU sec, 2.820 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20, 282259, 3, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (287, 346, 658)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1400)
[M::mem_pestat] mean and std.dev: (387.65, 185.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1771)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (234, 364, 498)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1026)
[M::mem_pestat] mean and std.dev: (375.80, 176.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1290)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (235, 298, 466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 928)
[M::mem_pestat] mean and std.dev: (319.29, 136.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1159)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 679926 reads in 179.032 CPU sec, 5.789 real sec
[M::process] read 678948 sequences (100000038 bp) in 2.097 CPU sec, 2.155 real sec...
[M::mem_process_seqs] Processed 679406 reads in 114.585 CPU sec, 3.665 real sec
sorting block 22, #reads = 1083271 mem = 536880429 peak = 985853952
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 282891, 4, 23)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 265, 408)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 846)
[M::mem_pestat] mean and std.dev: (263.59, 114.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1065)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (237, 365, 497)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1017)
[M::mem_pestat] mean and std.dev: (376.15, 175.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1277)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (231, 311, 522)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1104)
[M::mem_pestat] mean and std.dev: (295.25, 132.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1395)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 678952 sequences (100000239 bp) in 2.811 CPU sec, 3.248 real sec...
sorting block 23, #reads = 1082290 mem = 536877828 peak = 985853952
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20, 281700, 1, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (282, 348, 485)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 891)
[M::mem_pestat] mean and std.dev: (346.35, 154.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1094)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (237, 365, 497)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1017)
[M::mem_pestat] mean and std.dev: (376.44, 175.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1277)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 160, 374)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 808)
[M::mem_pestat] mean and std.dev: (247.97, 117.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1025)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 679208 reads in 174.432 CPU sec, 5.737 real sec
[M::process] read 678486 sequences (100000161 bp) in 2.086 CPU sec, 2.188 real sec...
[M::mem_process_seqs] Processed 678948 reads in 112.721 CPU sec, 3.705 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 282049, 3, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 235, 259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (7, 427)
[M::mem_pestat] mean and std.dev: (218.27, 52.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 511)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (240, 368, 500)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1020)
[M::mem_pestat] mean and std.dev: (378.58, 175.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1280)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 331, 404)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 842)
[M::mem_pestat] mean and std.dev: (315.59, 144.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1061)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 24, #reads = 1083288 mem = 536880875 peak = 985853952
[M::process] read 678446 sequences (100000097 bp) in 2.287 CPU sec, 2.711 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (21, 281576, 0, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 372, 5244)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 15326)
[M::mem_pestat] mean and std.dev: (2016.19, 2937.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 20367)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (241, 370, 502)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1024)
[M::mem_pestat] mean and std.dev: (380.38, 175.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1285)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 365, 515)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1189)
[M::mem_pestat] mean and std.dev: (338.94, 168.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1526)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 678952 reads in 175.472 CPU sec, 5.706 real sec
[M::process] read 678374 sequences (100000038 bp) in 2.016 CPU sec, 2.045 real sec...
[M::mem_process_seqs] Processed 678486 reads in 114.911 CPU sec, 3.709 real sec
sorting block 25, #reads = 1081052 mem = 536879215 peak = 985853952
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 282070, 6, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 298, 472)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 996)
[M::mem_pestat] mean and std.dev: (310.48, 152.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1258)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (242, 373, 505)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1031)
[M::mem_pestat] mean and std.dev: (382.33, 176.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1294)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 323, 595)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1419)
[M::mem_pestat] mean and std.dev: (357.19, 203.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1831)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 677996 sequences (100000176 bp) in 2.395 CPU sec, 2.763 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 282256, 1, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (267, 445, 516)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1014)
[M::mem_pestat] mean and std.dev: (346.00, 151.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1263)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 375, 508)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1036)
[M::mem_pestat] mean and std.dev: (384.30, 177.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1300)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (232, 414, 600)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1336)
[M::mem_pestat] mean and std.dev: (328.68, 149.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1704)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 678446 reads in 176.554 CPU sec, 5.774 real sec
[M::process] read 678152 sequences (100000270 bp) in 2.027 CPU sec, 2.074 real sec...
[M::mem_process_seqs] Processed 678374 reads in 114.057 CPU sec, 3.716 real sec
sorting block 26, #reads = 1081294 mem = 536877264 peak = 985853952
[M::process] read 677880 sequences (100000147 bp) in 2.483 CPU sec, 2.919 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 281878, 1, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (308, 466, 664)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1376)
[M::mem_pestat] mean and std.dev: (390.34, 169.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1732)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (246, 378, 511)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1041)
[M::mem_pestat] mean and std.dev: (386.57, 177.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1306)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 289, 435)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 961)
[M::mem_pestat] mean and std.dev: (293.79, 140.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1224)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 678152 reads in 98.081 CPU sec, 3.159 real sec
[M::process] read 677664 sequences (100000187 bp) in 2.077 CPU sec, 2.246 real sec...
sorting block 27, #reads = 1080685 mem = 536880751 peak = 985853952
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 281232, 2, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 175, 302)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 586)
[M::mem_pestat] mean and std.dev: (224.78, 110.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 728)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 377, 512)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1048)
[M::mem_pestat] mean and std.dev: (386.76, 178.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1316)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 342, 467)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 913)
[M::mem_pestat] mean and std.dev: (295.77, 133.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1136)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 281364, 8, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (246, 389, 572)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1224)
[M::mem_pestat] mean and std.dev: (336.00, 148.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1550)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (247, 379, 512)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1042)
[M::mem_pestat] mean and std.dev: (387.92, 177.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1307)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 208, 308)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 594)
[M::mem_pestat] mean and std.dev: (236.32, 92.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 737)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 677996 reads in 279.290 CPU sec, 9.167 real sec
[M::mem_process_seqs] Processed 677880 reads in 134.671 CPU sec, 4.458 real sec
[M::process] read 677572 sequences (100000266 bp) in 2.663 CPU sec, 3.082 real sec...
sorting block 28, #reads = 1080005 mem = 536878362 peak = 985853952
[M::process] read 677532 sequences (100000214 bp) in 2.611 CPU sec, 3.111 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 281993, 3, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 278, 349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 629)
[M::mem_pestat] mean and std.dev: (274.79, 119.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 769)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (250, 383, 516)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1048)
[M::mem_pestat] mean and std.dev: (391.05, 178.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1314)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 271, 442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 964)
[M::mem_pestat] mean and std.dev: (267.97, 132.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1225)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 677572 reads in 103.373 CPU sec, 3.353 real sec
sorting block 29, #reads = 1080088 mem = 536879684 peak = 985853952
[M::process] read 677356 sequences (100000051 bp) in 2.421 CPU sec, 2.820 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 280910, 5, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 284, 368)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 774)
[M::mem_pestat] mean and std.dev: (272.09, 134.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 977)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (250, 383, 516)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1048)
[M::mem_pestat] mean and std.dev: (391.27, 179.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1314)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (248, 311, 595)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1289)
[M::mem_pestat] mean and std.dev: (328.58, 150.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1636)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 281794, 3, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 284, 388)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 764)
[M::mem_pestat] mean and std.dev: (258.10, 112.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 952)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (248, 379, 512)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1040)
[M::mem_pestat] mean and std.dev: (387.91, 176.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1304)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 262, 449)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 995)
[M::mem_pestat] mean and std.dev: (307.79, 145.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1268)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 677664 reads in 280.118 CPU sec, 9.199 real sec
[M::mem_process_seqs] Processed 677532 reads in 132.204 CPU sec, 4.351 real sec
[M::process] read 677110 sequences (100000169 bp) in 2.542 CPU sec, 2.889 real sec...
sorting block 30, #reads = 1079059 mem = 536880455 peak = 985853952
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 281191, 2, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 289, 446)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 936)
[M::mem_pestat] mean and std.dev: (321.14, 152.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1181)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (251, 387, 519)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1055)
[M::mem_pestat] mean and std.dev: (393.55, 179.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1323)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 270, 467)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1005)
[M::mem_pestat] mean and std.dev: (358.37, 245.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1342)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 677376 sequences (100000245 bp) in 2.184 CPU sec, 2.834 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 281128, 10, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (298, 551, 977)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2335)
[M::mem_pestat] mean and std.dev: (497.37, 301.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3014)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (252, 385, 519)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1053)
[M::mem_pestat] mean and std.dev: (393.55, 179.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1320)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (516, 516, 1480)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3408)
[M::mem_pestat] mean and std.dev: (890.00, 591.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4372)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (247, 383, 753)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1765)
[M::mem_pestat] mean and std.dev: (385.44, 185.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2271)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 677356 reads in 180.790 CPU sec, 5.973 real sec
[M::mem_process_seqs] Processed 677110 reads in 114.707 CPU sec, 3.783 real sec
sorting block 31, #reads = 1080309 mem = 536878974 peak = 985853952
[M::process] read 677280 sequences (100000135 bp) in 2.386 CPU sec, 2.735 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 281777, 6, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 284, 775)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2011)
[M::mem_pestat] mean and std.dev: (412.19, 436.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2629)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (247, 374, 506)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1024)
[M::mem_pestat] mean and std.dev: (384.14, 174.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1283)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (281, 367, 766)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1736)
[M::mem_pestat] mean and std.dev: (509.28, 377.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2221)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 677080 sequences (100000027 bp) in 2.478 CPU sec, 2.810 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 281725, 7, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 438, 886)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2354)
[M::mem_pestat] mean and std.dev: (339.30, 240.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3088)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (249, 381, 514)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1044)
[M::mem_pestat] mean and std.dev: (389.92, 178.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1309)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 240, 408)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 818)
[M::mem_pestat] mean and std.dev: (300.52, 133.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1023)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 677376 reads in 179.071 CPU sec, 5.879 real sec
[M::mem_process_seqs] Processed 677280 reads in 115.418 CPU sec, 3.778 real sec
sorting block 32, #reads = 1078932 mem = 536877984 peak = 985853952
[M::process] read 677142 sequences (100000180 bp) in 2.390 CPU sec, 2.782 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 281754, 9, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 305, 376)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 806)
[M::mem_pestat] mean and std.dev: (255.25, 105.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1021)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (252, 385, 519)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1053)
[M::mem_pestat] mean and std.dev: (393.40, 178.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1320)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (309, 375, 742)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1608)
[M::mem_pestat] mean and std.dev: (391.44, 208.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2041)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 676882 sequences (100000202 bp) in 2.329 CPU sec, 2.750 real sec...
sorting block 33, #reads = 1078693 mem = 536878565 peak = 985853952
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 281581, 2, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 198, 443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1027)
[M::mem_pestat] mean and std.dev: (265.04, 143.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1319)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (250, 379, 512)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1036)
[M::mem_pestat] mean and std.dev: (388.62, 176.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1298)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 257, 452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1006)
[M::mem_pestat] mean and std.dev: (289.84, 162.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1283)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 677080 reads in 182.156 CPU sec, 5.919 real sec
[M::mem_process_seqs] Processed 677142 reads in 116.186 CPU sec, 3.750 real sec
[M::process] read 677496 sequences (100000255 bp) in 2.244 CPU sec, 2.477 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 281690, 4, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 246, 355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 641)
[M::mem_pestat] mean and std.dev: (258.48, 102.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 784)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (252, 384, 518)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1050)
[M::mem_pestat] mean and std.dev: (392.62, 178.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1316)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 278, 454)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1004)
[M::mem_pestat] mean and std.dev: (280.62, 127.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1279)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 34, #reads = 1079128 mem = 536878673 peak = 985853952
[M::process] read 677886 sequences (100000139 bp) in 2.660 CPU sec, 3.058 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 281537, 5, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 261, 388)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 784)
[M::mem_pestat] mean and std.dev: (258.62, 109.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 982)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (247, 379, 516)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1054)
[M::mem_pestat] mean and std.dev: (389.14, 178.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1323)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 256, 303)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 515)
[M::mem_pestat] mean and std.dev: (261.93, 112.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 713)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 676882 reads in 183.364 CPU sec, 5.938 real sec
[M::mem_process_seqs] Processed 677496 reads in 117.948 CPU sec, 3.783 real sec
[M::process] read 677042 sequences (100000184 bp) in 1.995 CPU sec, 2.044 real sec...
sorting block 35, #reads = 1078515 mem = 536883055 peak = 985853952
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (19, 282347, 2, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 299, 619)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1555)
[M::mem_pestat] mean and std.dev: (431.95, 279.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2023)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (243, 375, 512)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1050)
[M::mem_pestat] mean and std.dev: (386.22, 179.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1319)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 193, 347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 711)
[M::mem_pestat] mean and std.dev: (239.27, 111.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 893)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 677386 sequences (100000138 bp) in 2.497 CPU sec, 2.827 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 281580, 4, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 272, 391)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 747)
[M::mem_pestat] mean and std.dev: (338.49, 194.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1118)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (249, 381, 516)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1050)
[M::mem_pestat] mean and std.dev: (390.36, 177.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1317)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 339, 523)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1113)
[M::mem_pestat] mean and std.dev: (344.29, 162.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1408)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 677886 reads in 183.926 CPU sec, 5.923 real sec
[M::process] read 677654 sequences (100000061 bp) in 1.854 CPU sec, 1.879 real sec...
[M::mem_process_seqs] Processed 677042 reads in 119.753 CPU sec, 3.832 real sec
sorting block 36, #reads = 1078939 mem = 536881079 peak = 985853952
[M::process] read 677364 sequences (100000227 bp) in 2.852 CPU sec, 3.247 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 281852, 1, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (240, 394, 616)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1368)
[M::mem_pestat] mean and std.dev: (370.10, 158.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1744)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (245, 376, 512)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1046)
[M::mem_pestat] mean and std.dev: (386.78, 177.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1313)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 303, 462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 996)
[M::mem_pestat] mean and std.dev: (315.76, 130.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1263)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 677654 reads in 102.345 CPU sec, 3.268 real sec
[M::process] read 677186 sequences (100000039 bp) in 2.013 CPU sec, 2.077 real sec...
sorting block 37, #reads = 1076724 mem = 536877626 peak = 985853952
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 281391, 1, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (225, 289, 431)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 843)
[M::mem_pestat] mean and std.dev: (271.17, 93.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1049)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (247, 377, 511)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1039)
[M::mem_pestat] mean and std.dev: (387.66, 177.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1303)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (251, 300, 458)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 872)
[M::mem_pestat] mean and std.dev: (324.97, 132.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1079)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 281908, 1, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (145, 225, 310)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 640)
[M::mem_pestat] mean and std.dev: (228.36, 109.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 805)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (248, 381, 518)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1058)
[M::mem_pestat] mean and std.dev: (391.43, 179.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1328)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 269, 537)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1203)
[M::mem_pestat] mean and std.dev: (352.03, 187.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1536)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 677386 reads in 278.884 CPU sec, 9.028 real sec
[M::mem_process_seqs] Processed 677364 reads in 132.053 CPU sec, 4.297 real sec
[M::process] read 677372 sequences (100000002 bp) in 2.375 CPU sec, 2.743 real sec...
sorting block 38, #reads = 1078704 mem = 536880723 peak = 1008005120
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 281982, 0, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 295, 560)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1350)
[M::mem_pestat] mean and std.dev: (399.41, 325.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1745)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (245, 375, 509)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1037)
[M::mem_pestat] mean and std.dev: (386.33, 177.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1301)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 303, 904)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2290)
[M::mem_pestat] mean and std.dev: (380.30, 333.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2983)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 677004 sequences (100000166 bp) in 2.596 CPU sec, 3.035 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 281808, 3, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 283, 476)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1072)
[M::mem_pestat] mean and std.dev: (323.49, 172.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1370)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (246, 376, 513)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1047)
[M::mem_pestat] mean and std.dev: (387.92, 178.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1314)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (248, 356, 442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 830)
[M::mem_pestat] mean and std.dev: (315.44, 103.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1024)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 677186 reads in 178.283 CPU sec, 5.808 real sec
[M::mem_process_seqs] Processed 677372 reads in 116.311 CPU sec, 3.740 real sec
sorting block 39, #reads = 1079442 mem = 536877325 peak = 1008005120
[M::process] read 676920 sequences (100000238 bp) in 2.142 CPU sec, 2.284 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 281672, 3, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (245, 333, 499)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1007)
[M::mem_pestat] mean and std.dev: (383.02, 211.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1261)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (250, 384, 520)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1060)
[M::mem_pestat] mean and std.dev: (393.71, 180.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1330)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 328, 383)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 767)
[M::mem_pestat] mean and std.dev: (268.96, 104.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 959)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 676872 sequences (100000288 bp) in 2.317 CPU sec, 2.577 real sec...
sorting block 40, #reads = 1079325 mem = 536878582 peak = 1075265536
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 281977, 3, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 333, 420)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 878)
[M::mem_pestat] mean and std.dev: (315.74, 132.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1107)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (250, 386, 524)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1072)
[M::mem_pestat] mean and std.dev: (395.95, 182.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1346)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 231, 432)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 942)
[M::mem_pestat] mean and std.dev: (293.57, 147.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1197)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 677004 reads in 179.165 CPU sec, 5.867 real sec
[M::process] read 676852 sequences (100000135 bp) in 2.092 CPU sec, 2.280 real sec...
[M::mem_process_seqs] Processed 676920 reads in 116.203 CPU sec, 3.815 real sec
sorting block 41, #reads = 1078109 mem = 536877736 peak = 1075265536
[M::process] read 679716 sequences (100000057 bp) in 2.612 CPU sec, 3.105 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 282769, 0, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (257, 373, 2764)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7778)
[M::mem_pestat] mean and std.dev: (1454.72, 2057.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10285)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (253, 390, 529)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1081)
[M::mem_pestat] mean and std.dev: (399.77, 184.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1357)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 324, 631)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1533)
[M::mem_pestat] mean and std.dev: (330.21, 201.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1984)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 676852 reads in 97.843 CPU sec, 3.166 real sec
[M::process] read 680382 sequences (100000088 bp) in 2.272 CPU sec, 2.485 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 282082, 4, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 301, 440)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 918)
[M::mem_pestat] mean and std.dev: (295.06, 124.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1157)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (253, 390, 529)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1081)
[M::mem_pestat] mean and std.dev: (399.90, 184.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1357)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 243, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 694)
[M::mem_pestat] mean and std.dev: (259.30, 107.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 872)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 283282, 3, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 271, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 638)
[M::mem_pestat] mean and std.dev: (264.25, 108.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 776)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (234, 364, 501)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1035)
[M::mem_pestat] mean and std.dev: (377.41, 178.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1302)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (264, 334, 470)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 882)
[M::mem_pestat] mean and std.dev: (348.68, 133.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1088)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 676872 reads in 270.902 CPU sec, 8.797 real sec
sorting block 42, #reads = 1077778 mem = 536877637 peak = 1075265536
[M::mem_process_seqs] Processed 679716 reads in 129.794 CPU sec, 4.155 real sec
[M::process] read 679816 sequences (100000194 bp) in 2.478 CPU sec, 2.658 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 282962, 10, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (139, 201, 351)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 775)
[M::mem_pestat] mean and std.dev: (251.12, 155.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 987)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 358, 492)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1018)
[M::mem_pestat] mean and std.dev: (371.07, 176.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1281)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (2699, 7891, 7891)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 18275)
[M::mem_pestat] mean and std.dev: (5635.00, 2777.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 23467)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 261, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 698)
[M::mem_pestat] mean and std.dev: (242.68, 94.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 866)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 43, #reads = 1078929 mem = 536884929 peak = 1081602048
[M::process] read 679446 sequences (100000205 bp) in 2.625 CPU sec, 3.157 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 282802, 7, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 295, 456)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 920)
[M::mem_pestat] mean and std.dev: (304.49, 136.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1152)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (233, 362, 495)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1019)
[M::mem_pestat] mean and std.dev: (374.21, 176.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1281)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 347, 610)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1418)
[M::mem_pestat] mean and std.dev: (287.20, 136.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1822)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680382 reads in 170.291 CPU sec, 5.590 real sec
[M::mem_process_seqs] Processed 679816 reads in 108.786 CPU sec, 3.635 real sec
[M::process] read 678888 sequences (100000024 bp) in 2.427 CPU sec, 2.672 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 282740, 1, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 329, 670)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1612)
[M::mem_pestat] mean and std.dev: (404.04, 243.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2083)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (236, 367, 499)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1025)
[M::mem_pestat] mean and std.dev: (378.28, 177.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1288)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (316, 420, 579)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1105)
[M::mem_pestat] mean and std.dev: (422.68, 189.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1368)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 44, #reads = 1082007 mem = 536881417 peak = 1081602048
[M::process] read 678798 sequences (100000008 bp) in 2.632 CPU sec, 3.156 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (22, 282605, 4, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 245, 383)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 845)
[M::mem_pestat] mean and std.dev: (260.41, 130.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1076)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (239, 367, 500)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1022)
[M::mem_pestat] mean and std.dev: (378.83, 176.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1283)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 298, 378)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 714)
[M::mem_pestat] mean and std.dev: (288.89, 118.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 882)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 679446 reads in 171.370 CPU sec, 5.681 real sec
[M::mem_process_seqs] Processed 678888 reads in 111.227 CPU sec, 3.761 real sec
[M::process] read 678610 sequences (100000041 bp) in 2.374 CPU sec, 2.637 real sec...
sorting block 45, #reads = 1081856 mem = 536880154 peak = 1081602048
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 282641, 4, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 312, 523)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1147)
[M::mem_pestat] mean and std.dev: (363.19, 178.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1459)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (239, 368, 499)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1019)
[M::mem_pestat] mean and std.dev: (379.00, 176.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1279)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 384, 935)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2425)
[M::mem_pestat] mean and std.dev: (564.17, 540.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3170)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 678188 sequences (100000113 bp) in 2.610 CPU sec, 2.976 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (17, 283158, 2, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 245, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 669)
[M::mem_pestat] mean and std.dev: (204.21, 70.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 839)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (241, 371, 503)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1027)
[M::mem_pestat] mean and std.dev: (381.45, 177.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1289)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (242, 327, 476)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 944)
[M::mem_pestat] mean and std.dev: (338.81, 127.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1178)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 678798 reads in 174.696 CPU sec, 5.701 real sec
[M::mem_process_seqs] Processed 678610 reads in 112.354 CPU sec, 3.708 real sec
sorting block 46, #reads = 1080775 mem = 536881252 peak = 1081602048
[M::process] read 678106 sequences (100000202 bp) in 2.465 CPU sec, 2.768 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 282742, 3, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 285, 423)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 931)
[M::mem_pestat] mean and std.dev: (220.02, 89.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1185)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 374, 508)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1036)
[M::mem_pestat] mean and std.dev: (384.73, 178.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1300)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (276, 366, 452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 804)
[M::mem_pestat] mean and std.dev: (350.92, 117.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 980)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 678040 sequences (100000125 bp) in 2.602 CPU sec, 2.946 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 282463, 4, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 269, 490)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1008)
[M::mem_pestat] mean and std.dev: (269.28, 107.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1267)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 375, 507)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1033)
[M::mem_pestat] mean and std.dev: (384.67, 177.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1296)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (237, 338, 458)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 900)
[M::mem_pestat] mean and std.dev: (351.76, 154.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1121)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 678188 reads in 173.724 CPU sec, 5.665 real sec
sorting block 47, #reads = 1081359 mem = 536878851 peak = 1081602048
[M::process] read 677728 sequences (100000214 bp) in 2.035 CPU sec, 2.446 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 282606, 0, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 239, 474)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1066)
[M::mem_pestat] mean and std.dev: (257.00, 162.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1362)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (247, 380, 513)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1045)
[M::mem_pestat] mean and std.dev: (388.91, 179.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1311)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 336, 396)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 758)
[M::mem_pestat] mean and std.dev: (301.95, 139.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 939)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 678040 reads in 96.774 CPU sec, 3.185 real sec
[M::process] read 677768 sequences (100000145 bp) in 2.249 CPU sec, 2.485 real sec...
sorting block 48, #reads = 1080176 mem = 536879618 peak = 1081602048
[M::mem_process_seqs] Processed 678106 reads in 278.689 CPU sec, 9.123 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 282516, 0, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 255, 430)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 964)
[M::mem_pestat] mean and std.dev: (251.12, 134.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1231)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (248, 383, 516)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1052)
[M::mem_pestat] mean and std.dev: (391.19, 180.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1320)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 269, 450)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1012)
[M::mem_pestat] mean and std.dev: (307.24, 153.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1293)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 281800, 1, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 313, 480)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1106)
[M::mem_pestat] mean and std.dev: (303.66, 141.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1419)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (249, 386, 523)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1071)
[M::mem_pestat] mean and std.dev: (395.11, 182.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1345)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 260, 446)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 896)
[M::mem_pestat] mean and std.dev: (313.66, 142.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1121)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 677048 sequences (100000006 bp) in 2.836 CPU sec, 3.044 real sec...
[M::mem_process_seqs] Processed 677728 reads in 185.721 CPU sec, 5.952 real sec
[M::mem_process_seqs] Processed 677768 reads in 108.798 CPU sec, 3.468 real sec
sorting block 49, #reads = 1080067 mem = 536879871 peak = 1081602048
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 281405, 1, 20)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 298, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 701)
[M::mem_pestat] mean and std.dev: (269.43, 103.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 871)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (251, 384, 521)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1061)
[M::mem_pestat] mean and std.dev: (394.52, 181.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1331)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 202, 258)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (60, 390)
[M::mem_pestat] mean and std.dev: (201.18, 41.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 456)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 677154 sequences (100000288 bp) in 2.817 CPU sec, 3.037 real sec...
[M::mem_process_seqs] Processed 677048 reads in 92.322 CPU sec, 3.027 real sec
sorting block 50, #reads = 1081110 mem = 536876929 peak = 1081602048
[M::process] read 677004 sequences (100000015 bp) in 2.208 CPU sec, 2.376 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 282032, 2, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 263, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 598)
[M::mem_pestat] mean and std.dev: (246.10, 92.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 728)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (252, 384, 519)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1053)
[M::mem_pestat] mean and std.dev: (394.53, 181.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1320)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 319, 464)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 936)
[M::mem_pestat] mean and std.dev: (337.85, 161.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1172)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 676868 sequences (100000238 bp) in 2.021 CPU sec, 2.185 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 282086, 7, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (140, 278, 403)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 929)
[M::mem_pestat] mean and std.dev: (313.00, 181.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1192)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (252, 385, 521)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1059)
[M::mem_pestat] mean and std.dev: (395.14, 181.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1328)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 354, 431)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 843)
[M::mem_pestat] mean and std.dev: (355.80, 166.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1049)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 677154 reads in 174.227 CPU sec, 5.544 real sec
[M::process] read 676882 sequences (100000122 bp) in 1.817 CPU sec, 1.860 real sec...
[M::mem_process_seqs] Processed 677004 reads in 112.596 CPU sec, 3.583 real sec
sorting block 51, #reads = 1079734 mem = 536879073 peak = 1081602048
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 281860, 2, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (250, 406, 475)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 925)
[M::mem_pestat] mean and std.dev: (359.15, 143.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1150)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (253, 385, 521)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1057)
[M::mem_pestat] mean and std.dev: (395.35, 181.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1325)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 283, 434)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 928)
[M::mem_pestat] mean and std.dev: (287.91, 132.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1175)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 52, #reads = 1080041 mem = 536880136 peak = 1081602048
[M::process] read 676764 sequences (100000053 bp) in 2.932 CPU sec, 3.435 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 281249, 1, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 518, 2576)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7402)
[M::mem_pestat] mean and std.dev: (1409.48, 1812.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9815)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (254, 386, 522)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1058)
[M::mem_pestat] mean and std.dev: (395.97, 180.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1326)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 287, 389)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 781)
[M::mem_pestat] mean and std.dev: (284.38, 112.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 977)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 676868 reads in 177.596 CPU sec, 5.704 real sec
[M::process] read 676650 sequences (100000279 bp) in 1.871 CPU sec, 1.976 real sec...
[M::mem_process_seqs] Processed 676882 reads in 114.018 CPU sec, 3.643 real sec
sorting block 53, #reads = 1078298 mem = 536878037 peak = 1081602048
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 281629, 1, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (370, 464, 587)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1021)
[M::mem_pestat] mean and std.dev: (449.10, 162.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1238)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (254, 387, 523)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1061)
[M::mem_pestat] mean and std.dev: (396.85, 181.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1330)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 379, 512)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1092)
[M::mem_pestat] mean and std.dev: (358.56, 197.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1382)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 677112 sequences (100000056 bp) in 2.287 CPU sec, 2.748 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 281507, 3, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 359, 546)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1206)
[M::mem_pestat] mean and std.dev: (360.70, 207.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1536)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (256, 389, 523)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1057)
[M::mem_pestat] mean and std.dev: (397.34, 180.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1324)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 238, 482)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1040)
[M::mem_pestat] mean and std.dev: (270.18, 124.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1319)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 676764 reads in 174.169 CPU sec, 5.604 real sec
[M::process] read 676788 sequences (100000018 bp) in 1.781 CPU sec, 1.788 real sec...
[M::mem_process_seqs] Processed 676650 reads in 113.071 CPU sec, 3.602 real sec
sorting block 54, #reads = 1079549 mem = 536877942 peak = 1081602048
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 282067, 7, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (146, 281, 304)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 620)
[M::mem_pestat] mean and std.dev: (238.93, 105.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 778)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (248, 377, 512)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1040)
[M::mem_pestat] mean and std.dev: (388.45, 178.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1304)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 326, 502)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1064)
[M::mem_pestat] mean and std.dev: (319.63, 182.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1345)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 677262 sequences (100000152 bp) in 2.758 CPU sec, 3.253 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 281550, 3, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 282, 449)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 955)
[M::mem_pestat] mean and std.dev: (288.42, 117.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1208)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (251, 384, 520)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1058)
[M::mem_pestat] mean and std.dev: (394.71, 181.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1327)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (300, 413, 537)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1011)
[M::mem_pestat] mean and std.dev: (395.17, 147.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1248)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 677112 reads in 176.349 CPU sec, 5.700 real sec
[M::mem_process_seqs] Processed 676788 reads in 113.766 CPU sec, 3.638 real sec
[M::process] read 677398 sequences (100000232 bp) in 2.075 CPU sec, 2.159 real sec...
sorting block 55, #reads = 1079140 mem = 536877473 peak = 1081602048
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 281392, 2, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 294, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (24, 519)
[M::mem_pestat] mean and std.dev: (276.65, 107.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 707)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (249, 380, 516)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1050)
[M::mem_pestat] mean and std.dev: (391.80, 181.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1317)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 367, 399)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 755)
[M::mem_pestat] mean and std.dev: (305.26, 136.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 933)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 677002 sequences (100000010 bp) in 2.364 CPU sec, 2.529 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 281465, 2, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 269, 557)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1331)
[M::mem_pestat] mean and std.dev: (375.80, 323.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1718)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (248, 378, 514)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1046)
[M::mem_pestat] mean and std.dev: (389.93, 180.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1312)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 271, 370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 692)
[M::mem_pestat] mean and std.dev: (275.90, 82.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 853)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 677262 reads in 173.607 CPU sec, 5.550 real sec
[M::process] read 677494 sequences (100000017 bp) in 1.860 CPU sec, 1.859 real sec...
[M::mem_process_seqs] Processed 677398 reads in 111.257 CPU sec, 3.514 real sec
sorting block 56, #reads = 1079528 mem = 536882095 peak = 1081602048
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20, 281683, 2, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 417, 649)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1563)
[M::mem_pestat] mean and std.dev: (413.68, 294.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2020)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (248, 380, 517)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1055)
[M::mem_pestat] mean and std.dev: (391.60, 180.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1324)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 339, 495)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1117)
[M::mem_pestat] mean and std.dev: (291.96, 124.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1428)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 57, #reads = 1079350 mem = 536879076 peak = 1081602048
[M::process] read 677406 sequences (100000122 bp) in 2.646 CPU sec, 2.801 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 281579, 3, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (324, 408, 588)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1116)
[M::mem_pestat] mean and std.dev: (415.66, 148.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1380)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 376, 514)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1054)
[M::mem_pestat] mean and std.dev: (388.58, 181.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1324)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 288, 486)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1044)
[M::mem_pestat] mean and std.dev: (386.00, 241.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1352)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 677412 sequences (100000188 bp) in 1.837 CPU sec, 1.847 real sec...
[M::mem_process_seqs] Processed 677002 reads in 170.468 CPU sec, 5.419 real sec
[M::mem_process_seqs] Processed 677494 reads in 110.383 CPU sec, 3.486 real sec
sorting block 58, #reads = 1078966 mem = 536879042 peak = 1081602048
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 281829, 2, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (118, 244, 467)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1165)
[M::mem_pestat] mean and std.dev: (260.20, 150.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1514)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (246, 375, 512)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1044)
[M::mem_pestat] mean and std.dev: (387.44, 179.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1310)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 318, 633)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1453)
[M::mem_pestat] mean and std.dev: (296.19, 133.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1863)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 677472 sequences (100000134 bp) in 2.392 CPU sec, 2.529 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 282205, 5, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 389, 1284)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3444)
[M::mem_pestat] mean and std.dev: (560.50, 529.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4524)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (245, 374, 510)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1040)
[M::mem_pestat] mean and std.dev: (386.26, 179.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1305)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 267, 356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 654)
[M::mem_pestat] mean and std.dev: (265.29, 81.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 803)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 677486 sequences (100000094 bp) in 2.014 CPU sec, 2.024 real sec...
[M::mem_process_seqs] Processed 677406 reads in 168.768 CPU sec, 5.362 real sec
[M::mem_process_seqs] Processed 677412 reads in 109.702 CPU sec, 3.464 real sec
sorting block 59, #reads = 1078697 mem = 536876741 peak = 1081602048
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 281410, 4, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 299, 546)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1222)
[M::mem_pestat] mean and std.dev: (290.90, 137.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1560)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 374, 510)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1042)
[M::mem_pestat] mean and std.dev: (386.57, 179.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1308)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (285, 347, 417)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (21, 681)
[M::mem_pestat] mean and std.dev: (328.82, 98.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 813)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 677386 sequences (100000017 bp) in 2.708 CPU sec, 2.837 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 282341, 3, 24)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 274, 562)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1326)
[M::mem_pestat] mean and std.dev: (315.16, 206.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1708)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (243, 371, 507)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1035)
[M::mem_pestat] mean and std.dev: (384.04, 178.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1299)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 273, 369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 765)
[M::mem_pestat] mean and std.dev: (257.10, 111.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 963)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 677472 reads in 165.317 CPU sec, 5.263 real sec
[M::process] read 677182 sequences (100000079 bp) in 1.800 CPU sec, 1.807 real sec...
[M::mem_process_seqs] Processed 677486 reads in 105.354 CPU sec, 3.338 real sec
sorting block 60, #reads = 1078506 mem = 536879266 peak = 1081602048
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 281503, 9, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 280, 550)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1280)
[M::mem_pestat] mean and std.dev: (297.55, 142.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1645)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (246, 375, 512)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1044)
[M::mem_pestat] mean and std.dev: (388.47, 180.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1310)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 276, 374)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 700)
[M::mem_pestat] mean and std.dev: (298.13, 129.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 863)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 677140 sequences (100000128 bp) in 2.582 CPU sec, 2.783 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 281603, 5, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 213, 346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 694)
[M::mem_pestat] mean and std.dev: (250.77, 132.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 868)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (248, 379, 517)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1055)
[M::mem_pestat] mean and std.dev: (391.55, 182.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1324)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 221, 371)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 741)
[M::mem_pestat] mean and std.dev: (269.72, 144.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 926)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 677386 reads in 168.146 CPU sec, 5.346 real sec
[M::process] read 676678 sequences (100000219 bp) in 1.820 CPU sec, 1.826 real sec...
sorting block 61, #reads = 1079352 mem = 536878034 peak = 1081602048
[M::mem_process_seqs] Processed 677182 reads in 107.661 CPU sec, 3.391 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 282068, 4, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 326, 386)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 766)
[M::mem_pestat] mean and std.dev: (272.88, 91.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 956)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (249, 382, 521)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1065)
[M::mem_pestat] mean and std.dev: (394.44, 183.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1337)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 246, 500)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1142)
[M::mem_pestat] mean and std.dev: (255.22, 127.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1463)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 62, #reads = 1077857 mem = 536881608 peak = 1081602048
[M::process] read 676994 sequences (100000076 bp) in 3.135 CPU sec, 3.357 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 282011, 0, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 271, 375)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 695)
[M::mem_pestat] mean and std.dev: (281.71, 108.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 855)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (252, 388, 529)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1083)
[M::mem_pestat] mean and std.dev: (400.16, 186.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1360)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 287, 510)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1106)
[M::mem_pestat] mean and std.dev: (310.18, 146.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1404)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 677140 reads in 165.037 CPU sec, 5.242 real sec
[M::mem_process_seqs] Processed 676678 reads in 104.694 CPU sec, 3.303 real sec
[M::process] read 676244 sequences (100000169 bp) in 2.464 CPU sec, 2.572 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 282320, 2, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (144, 327, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 732)
[M::mem_pestat] mean and std.dev: (253.16, 117.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 928)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (251, 387, 527)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1079)
[M::mem_pestat] mean and std.dev: (398.45, 185.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1355)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 301, 951)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2437)
[M::mem_pestat] mean and std.dev: (421.29, 402.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3180)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 63, #reads = 1078958 mem = 536876880 peak = 1081602048
[M::process] read 677656 sequences (100000197 bp) in 2.518 CPU sec, 2.656 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23, 282202, 0, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (225, 234, 466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 948)
[M::mem_pestat] mean and std.dev: (308.13, 136.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1189)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (258, 398, 539)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1101)
[M::mem_pestat] mean and std.dev: (408.46, 189.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1382)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (250, 347, 572)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1216)
[M::mem_pestat] mean and std.dev: (358.77, 154.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1538)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 676994 reads in 165.505 CPU sec, 5.283 real sec
[M::mem_process_seqs] Processed 676244 reads in 106.482 CPU sec, 3.352 real sec
[M::process] read 680322 sequences (100000167 bp) in 2.186 CPU sec, 2.261 real sec...
sorting block 64, #reads = 1077958 mem = 536881317 peak = 1081602048
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 282559, 4, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (264, 494, 653)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1431)
[M::mem_pestat] mean and std.dev: (462.71, 219.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1820)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (246, 383, 524)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1080)
[M::mem_pestat] mean and std.dev: (394.70, 185.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1358)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 364, 494)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1072)
[M::mem_pestat] mean and std.dev: (375.38, 210.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1361)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 679804 sequences (100000063 bp) in 2.799 CPU sec, 2.963 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 282508, 0, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 294, 409)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 833)
[M::mem_pestat] mean and std.dev: (310.88, 154.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1045)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (230, 361, 498)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1034)
[M::mem_pestat] mean and std.dev: (374.39, 178.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1302)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (239, 318, 458)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 896)
[M::mem_pestat] mean and std.dev: (319.21, 120.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1115)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 677656 reads in 170.511 CPU sec, 5.429 real sec
[M::mem_process_seqs] Processed 680322 reads in 108.531 CPU sec, 3.416 real sec
[M::process] read 679136 sequences (100000049 bp) in 2.072 CPU sec, 2.122 real sec...
sorting block 65, #reads = 1078258 mem = 536880332 peak = 1081602048
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 281859, 1, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 293, 439)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 881)
[M::mem_pestat] mean and std.dev: (288.50, 119.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1102)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (235, 366, 503)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1039)
[M::mem_pestat] mean and std.dev: (379.08, 180.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1307)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (234, 317, 416)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 780)
[M::mem_pestat] mean and std.dev: (332.41, 139.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 962)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 678528 sequences (100000087 bp) in 2.468 CPU sec, 2.608 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 282296, 1, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (143, 204, 438)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1028)
[M::mem_pestat] mean and std.dev: (291.70, 179.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1323)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (238, 370, 510)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1054)
[M::mem_pestat] mean and std.dev: (383.65, 181.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1326)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 462, 696)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1652)
[M::mem_pestat] mean and std.dev: (403.11, 236.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2130)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 679804 reads in 168.905 CPU sec, 5.383 real sec
[M::process] read 678502 sequences (100000071 bp) in 1.777 CPU sec, 1.781 real sec...
sorting block 66, #reads = 1081406 mem = 536880053 peak = 1081602048
[M::mem_process_seqs] Processed 679136 reads in 105.950 CPU sec, 3.345 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 281701, 1, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 304, 562)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1318)
[M::mem_pestat] mean and std.dev: (387.03, 234.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1696)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (242, 378, 517)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1067)
[M::mem_pestat] mean and std.dev: (389.49, 183.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1342)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (262, 330, 573)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1195)
[M::mem_pestat] mean and std.dev: (399.56, 201.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1506)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 67, #reads = 1083116 mem = 536880198 peak = 1089875968
[M::process] read 678240 sequences (100000277 bp) in 2.563 CPU sec, 2.711 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 281499, 3, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (232, 377, 622)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1402)
[M::mem_pestat] mean and std.dev: (422.24, 284.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1792)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (243, 376, 513)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1053)
[M::mem_pestat] mean and std.dev: (387.38, 181.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1323)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 270, 377)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 723)
[M::mem_pestat] mean and std.dev: (270.58, 95.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 896)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 678528 reads in 165.357 CPU sec, 5.261 real sec
[M::process] read 678054 sequences (100000154 bp) in 1.953 CPU sec, 1.964 real sec...
[M::mem_process_seqs] Processed 678502 reads in 104.353 CPU sec, 3.289 real sec
sorting block 68, #reads = 1081953 mem = 536880367 peak = 1089875968
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 281649, 10, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 300, 560)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1294)
[M::mem_pestat] mean and std.dev: (321.25, 180.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1661)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (243, 375, 511)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1047)
[M::mem_pestat] mean and std.dev: (386.62, 180.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1315)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (636, 636, 1086)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1986)
[M::mem_pestat] mean and std.dev: (587.50, 258.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2436)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (262, 368, 526)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1054)
[M::mem_pestat] mean and std.dev: (308.40, 124.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1318)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 677804 sequences (100000188 bp) in 2.382 CPU sec, 2.518 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 281697, 2, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (138, 369, 453)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1083)
[M::mem_pestat] mean and std.dev: (310.25, 137.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1398)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (245, 375, 512)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1046)
[M::mem_pestat] mean and std.dev: (387.06, 179.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1313)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 271, 440)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 962)
[M::mem_pestat] mean and std.dev: (284.12, 140.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1223)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 677404 sequences (100000137 bp) in 1.790 CPU sec, 1.793 real sec...
[M::mem_process_seqs] Processed 678240 reads in 161.480 CPU sec, 5.132 real sec
[M::mem_process_seqs] Processed 678054 reads in 102.984 CPU sec, 3.247 real sec
sorting block 69, #reads = 1080715 mem = 536878027 peak = 1089875968
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 281148, 3, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 362, 556)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1302)
[M::mem_pestat] mean and std.dev: (348.32, 173.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1675)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (247, 381, 518)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1060)
[M::mem_pestat] mean and std.dev: (391.98, 182.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1331)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 391, 485)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1013)
[M::mem_pestat] mean and std.dev: (333.04, 150.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1277)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 677430 sequences (100000160 bp) in 2.716 CPU sec, 2.839 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 282075, 5, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 258, 408)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 876)
[M::mem_pestat] mean and std.dev: (252.21, 126.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1110)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (251, 387, 524)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1070)
[M::mem_pestat] mean and std.dev: (396.49, 183.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1343)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 336, 534)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1236)
[M::mem_pestat] mean and std.dev: (327.32, 174.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1587)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 677356 sequences (100000277 bp) in 1.790 CPU sec, 1.796 real sec...
[M::mem_process_seqs] Processed 677804 reads in 161.010 CPU sec, 5.102 real sec
[M::mem_process_seqs] Processed 677404 reads in 101.909 CPU sec, 3.216 real sec
sorting block 70, #reads = 1081099 mem = 536878184 peak = 1089875968
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 280998, 0, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (234, 294, 421)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 795)
[M::mem_pestat] mean and std.dev: (260.32, 86.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 982)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (251, 386, 523)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1067)
[M::mem_pestat] mean and std.dev: (395.55, 182.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1339)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (299, 500, 4483)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12851)
[M::mem_pestat] mean and std.dev: (1838.27, 2074.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17035)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 677208 sequences (100000172 bp) in 2.391 CPU sec, 2.536 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 281214, 3, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 263, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 664)
[M::mem_pestat] mean and std.dev: (255.89, 105.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 828)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (252, 390, 529)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1083)
[M::mem_pestat] mean and std.dev: (399.00, 184.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1360)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (243, 294, 426)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 792)
[M::mem_pestat] mean and std.dev: (301.85, 128.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 975)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 677110 sequences (100000122 bp) in 1.853 CPU sec, 1.858 real sec...
[M::mem_process_seqs] Processed 677430 reads in 168.613 CPU sec, 5.357 real sec
sorting block 71, #reads = 1080995 mem = 536878658 peak = 1089875968
[M::mem_process_seqs] Processed 677356 reads in 106.447 CPU sec, 3.362 real sec
sorting block 72, #reads = 1080721 mem = 536877552 peak = 1125601280
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 281192, 2, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 314, 465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1065)
[M::mem_pestat] mean and std.dev: (281.78, 153.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1365)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (253, 389, 527)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1075)
[M::mem_pestat] mean and std.dev: (398.54, 183.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1349)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (239, 288, 497)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1013)
[M::mem_pestat] mean and std.dev: (324.87, 140.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1271)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 676990 sequences (100000297 bp) in 2.741 CPU sec, 2.878 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23, 281064, 6, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (136, 231, 1092)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3004)
[M::mem_pestat] mean and std.dev: (375.20, 373.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3960)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (254, 392, 531)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1085)
[M::mem_pestat] mean and std.dev: (400.87, 184.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1362)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (257, 383, 547)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1127)
[M::mem_pestat] mean and std.dev: (343.86, 131.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1417)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 677022 sequences (100000134 bp) in 1.840 CPU sec, 1.845 real sec...
[M::mem_process_seqs] Processed 677208 reads in 167.329 CPU sec, 5.298 real sec
[M::mem_process_seqs] Processed 677110 reads in 103.567 CPU sec, 3.268 real sec
sorting block 73, #reads = 1080998 mem = 536881074 peak = 1125601280
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (22, 281756, 6, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 334, 658)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1640)
[M::mem_pestat] mean and std.dev: (271.35, 149.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2131)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (253, 389, 526)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1072)
[M::mem_pestat] mean and std.dev: (397.92, 182.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1345)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (263, 380, 510)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1004)
[M::mem_pestat] mean and std.dev: (380.43, 156.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1251)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 677106 sequences (100000185 bp) in 2.153 CPU sec, 2.277 real sec...
[M::process] read 677020 sequences (100000224 bp) in 1.479 CPU sec, 1.486 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 281505, 1, 21)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 288, 499)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1119)
[M::mem_pestat] mean and std.dev: (324.07, 155.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1429)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (253, 389, 527)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1075)
[M::mem_pestat] mean and std.dev: (398.15, 182.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1349)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (352, 375, 622)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1162)
[M::mem_pestat] mean and std.dev: (367.94, 131.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1432)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 676990 reads in 163.105 CPU sec, 5.200 real sec
[M::mem_process_seqs] Processed 677022 reads in 102.057 CPU sec, 3.245 real sec
sorting block 74, #reads = 1080776 mem = 536882336 peak = 1125601280
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 281745, 2, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 286, 617)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1527)
[M::mem_pestat] mean and std.dev: (289.00, 195.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1982)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (252, 388, 525)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1071)
[M::mem_pestat] mean and std.dev: (396.34, 181.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1344)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (239, 399, 470)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 932)
[M::mem_pestat] mean and std.dev: (365.36, 132.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1163)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 676874 sequences (100000089 bp) in 3.140 CPU sec, 3.325 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 281141, 3, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 288, 428)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 956)
[M::mem_pestat] mean and std.dev: (351.30, 238.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1306)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (252, 386, 523)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1065)
[M::mem_pestat] mean and std.dev: (395.58, 181.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1336)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 323, 570)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1270)
[M::mem_pestat] mean and std.dev: (327.23, 147.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1620)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 677106 reads in 166.082 CPU sec, 5.281 real sec
[M::mem_process_seqs] Processed 677020 reads in 104.804 CPU sec, 3.298 real sec
[M::process] read 676352 sequences (100000106 bp) in 2.080 CPU sec, 2.140 real sec...
sorting block 75, #reads = 1079113 mem = 536877686 peak = 1125601280
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 281157, 0, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (226, 247, 410)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 778)
[M::mem_pestat] mean and std.dev: (295.92, 132.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 962)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (253, 386, 522)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1060)
[M::mem_pestat] mean and std.dev: (394.96, 179.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1329)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (238, 354, 461)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 907)
[M::mem_pestat] mean and std.dev: (322.38, 125.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1130)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 76, #reads = 1079260 mem = 536879221 peak = 1125601280
[M::process] read 676518 sequences (100000266 bp) in 1.909 CPU sec, 2.067 real sec...
[M::process] read 677708 sequences (100000030 bp) in 1.520 CPU sec, 1.511 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 281163, 2, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 269, 305)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 543)
[M::mem_pestat] mean and std.dev: (225.91, 79.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 662)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (255, 388, 523)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1059)
[M::mem_pestat] mean and std.dev: (396.77, 179.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1327)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 316, 412)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 862)
[M::mem_pestat] mean and std.dev: (307.51, 145.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1087)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 676874 reads in 164.134 CPU sec, 5.236 real sec
[M::mem_process_seqs] Processed 676352 reads in 104.692 CPU sec, 3.326 real sec
sorting block 77, #reads = 1079175 mem = 536880778 peak = 1125601280
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 280823, 1, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 238, 353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 741)
[M::mem_pestat] mean and std.dev: (239.00, 110.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 935)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (253, 387, 525)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1069)
[M::mem_pestat] mean and std.dev: (397.15, 181.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1341)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 271, 447)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 903)
[M::mem_pestat] mean and std.dev: (286.35, 137.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1131)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 678000 sequences (100000067 bp) in 2.709 CPU sec, 2.832 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 281892, 1, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 199, 397)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 883)
[M::mem_pestat] mean and std.dev: (244.46, 106.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1126)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 374, 511)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1045)
[M::mem_pestat] mean and std.dev: (385.87, 178.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1312)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 322, 476)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 986)
[M::mem_pestat] mean and std.dev: (348.75, 172.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1241)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 677724 sequences (100000292 bp) in 1.850 CPU sec, 1.859 real sec...
[M::mem_process_seqs] Processed 676518 reads in 165.666 CPU sec, 5.251 real sec
[M::mem_process_seqs] Processed 677708 reads in 105.842 CPU sec, 3.347 real sec
sorting block 78, #reads = 1078963 mem = 536877439 peak = 1125601280
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20, 281395, 3, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 315, 920)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2370)
[M::mem_pestat] mean and std.dev: (471.45, 385.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3095)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (242, 371, 506)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1034)
[M::mem_pestat] mean and std.dev: (382.52, 176.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1298)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 292, 391)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 751)
[M::mem_pestat] mean and std.dev: (284.35, 130.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 931)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 677450 sequences (100000174 bp) in 2.593 CPU sec, 2.765 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 281386, 3, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 324, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 622)
[M::mem_pestat] mean and std.dev: (272.97, 85.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 762)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (243, 373, 509)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1041)
[M::mem_pestat] mean and std.dev: (384.78, 177.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1307)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 282, 704)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1670)
[M::mem_pestat] mean and std.dev: (346.62, 248.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2153)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 677340 sequences (100000002 bp) in 1.820 CPU sec, 1.820 real sec...
[M::mem_process_seqs] Processed 678000 reads in 169.763 CPU sec, 5.386 real sec
[M::mem_process_seqs] Processed 677724 reads in 105.842 CPU sec, 3.341 real sec
sorting block 79, #reads = 1080705 mem = 536878050 peak = 1125601280
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 281021, 3, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 218, 310)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 612)
[M::mem_pestat] mean and std.dev: (219.05, 77.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 763)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 374, 508)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1036)
[M::mem_pestat] mean and std.dev: (384.90, 176.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1300)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 302, 548)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1278)
[M::mem_pestat] mean and std.dev: (310.17, 171.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1643)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 677514 sequences (100000123 bp) in 2.577 CPU sec, 2.706 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 281614, 4, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 323, 488)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1028)
[M::mem_pestat] mean and std.dev: (330.30, 148.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1298)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 374, 510)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1042)
[M::mem_pestat] mean and std.dev: (385.62, 177.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1308)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (329, 412, 480)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (27, 782)
[M::mem_pestat] mean and std.dev: (372.54, 122.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 933)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 677740 sequences (100000292 bp) in 1.879 CPU sec, 1.880 real sec...
[M::mem_process_seqs] Processed 677450 reads in 168.411 CPU sec, 5.351 real sec
sorting block 80, #reads = 1078437 mem = 536878966 peak = 1125601280
[M::mem_process_seqs] Processed 677340 reads in 105.332 CPU sec, 3.335 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 282075, 4, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 304, 449)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 941)
[M::mem_pestat] mean and std.dev: (332.49, 182.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1187)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 373, 508)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1036)
[M::mem_pestat] mean and std.dev: (384.86, 177.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1300)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (241, 336, 545)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1153)
[M::mem_pestat] mean and std.dev: (356.44, 186.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1457)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 81, #reads = 1078691 mem = 536878281 peak = 1125601280
[M::process] read 677748 sequences (100000153 bp) in 2.665 CPU sec, 2.802 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 281810, 6, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (131, 273, 788)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2102)
[M::mem_pestat] mean and std.dev: (344.86, 307.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2759)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (242, 370, 504)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1028)
[M::mem_pestat] mean and std.dev: (381.94, 175.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1290)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 393, 941)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2467)
[M::mem_pestat] mean and std.dev: (420.80, 312.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3230)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 677514 reads in 163.855 CPU sec, 5.203 real sec
[M::process] read 677542 sequences (100000036 bp) in 1.888 CPU sec, 1.898 real sec...
[M::mem_process_seqs] Processed 677740 reads in 104.409 CPU sec, 3.288 real sec
sorting block 82, #reads = 1079460 mem = 536877890 peak = 1125601280
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 281769, 0, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 273, 505)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1101)
[M::mem_pestat] mean and std.dev: (355.34, 215.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1399)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (243, 371, 507)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1035)
[M::mem_pestat] mean and std.dev: (383.23, 177.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1299)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (245, 374, 898)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2204)
[M::mem_pestat] mean and std.dev: (352.61, 230.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2857)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 677180 sequences (100000219 bp) in 2.796 CPU sec, 2.943 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 281736, 8, 24)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 246, 494)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1146)
[M::mem_pestat] mean and std.dev: (308.52, 179.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1472)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (246, 376, 512)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1044)
[M::mem_pestat] mean and std.dev: (387.16, 177.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1310)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 238, 278)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 524)
[M::mem_pestat] mean and std.dev: (218.65, 82.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 647)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 677450 sequences (100000085 bp) in 1.610 CPU sec, 1.607 real sec...
[M::mem_process_seqs] Processed 677748 reads in 165.181 CPU sec, 5.244 real sec
[M::mem_process_seqs] Processed 677542 reads in 105.883 CPU sec, 3.348 real sec
sorting block 83, #reads = 1079488 mem = 536880115 peak = 1125601280
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (22, 281511, 3, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 244, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 729)
[M::mem_pestat] mean and std.dev: (253.18, 101.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 910)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (248, 379, 515)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1049)
[M::mem_pestat] mean and std.dev: (389.91, 178.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1316)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (234, 390, 447)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 873)
[M::mem_pestat] mean and std.dev: (323.52, 136.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1086)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 677094 sequences (100000052 bp) in 2.530 CPU sec, 2.654 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 281785, 8, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 180, 304)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 592)
[M::mem_pestat] mean and std.dev: (237.83, 107.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 736)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (246, 376, 513)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1047)
[M::mem_pestat] mean and std.dev: (387.82, 178.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1314)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 341, 479)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1005)
[M::mem_pestat] mean and std.dev: (359.42, 166.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1268)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 677180 reads in 164.091 CPU sec, 5.220 real sec
[M::process] read 676082 sequences (100000059 bp) in 1.838 CPU sec, 1.842 real sec...
[M::mem_process_seqs] Processed 677450 reads in 105.103 CPU sec, 3.313 real sec
sorting block 84, #reads = 1079122 mem = 536879262 peak = 1125601280
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 282294, 2, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 260, 578)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1346)
[M::mem_pestat] mean and std.dev: (324.57, 188.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1730)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (249, 381, 520)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1062)
[M::mem_pestat] mean and std.dev: (392.73, 181.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1333)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (271, 340, 503)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 967)
[M::mem_pestat] mean and std.dev: (335.56, 129.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1199)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 676260 sequences (100000245 bp) in 2.510 CPU sec, 2.623 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 281555, 4, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 349, 525)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1241)
[M::mem_pestat] mean and std.dev: (308.45, 149.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1599)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (257, 391, 529)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1073)
[M::mem_pestat] mean and std.dev: (400.77, 182.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1345)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 347, 375)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 711)
[M::mem_pestat] mean and std.dev: (299.42, 132.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 879)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 677274 sequences (100000193 bp) in 1.844 CPU sec, 1.850 real sec...
[M::mem_process_seqs] Processed 677094 reads in 161.107 CPU sec, 5.112 real sec
sorting block 85, #reads = 1078628 mem = 536879779 peak = 1125601280
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 281716, 0, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 394, 659)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1649)
[M::mem_pestat] mean and std.dev: (391.60, 294.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2144)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (256, 392, 531)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1081)
[M::mem_pestat] mean and std.dev: (401.69, 183.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1356)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (233, 396, 521)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1097)
[M::mem_pestat] mean and std.dev: (377.55, 171.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1385)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 679560 sequences (100000122 bp) in 1.773 CPU sec, 1.780 real sec...
[M::mem_process_seqs] Processed 676260 reads in 88.712 CPU sec, 2.809 real sec
sorting block 86, #reads = 1078619 mem = 536879564 peak = 1125601280
[M::mem_process_seqs] Processed 676082 reads in 222.078 CPU sec, 7.044 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 282630, 7, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (137, 190, 400)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 926)
[M::mem_pestat] mean and std.dev: (225.36, 127.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1189)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (249, 385, 523)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1071)
[M::mem_pestat] mean and std.dev: (395.11, 183.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1345)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (258, 386, 804)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1896)
[M::mem_pestat] mean and std.dev: (459.89, 294.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2442)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 685286 sequences (100000216 bp) in 2.949 CPU sec, 3.070 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 283118, 3, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (138, 267, 498)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1218)
[M::mem_pestat] mean and std.dev: (252.47, 144.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1578)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (234, 371, 514)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1074)
[M::mem_pestat] mean and std.dev: (384.02, 183.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1354)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (242, 254, 437)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 827)
[M::mem_pestat] mean and std.dev: (306.47, 154.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1022)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 677274 reads in 176.091 CPU sec, 5.595 real sec
[M::mem_process_seqs] Processed 679560 reads in 107.276 CPU sec, 3.380 real sec
sorting block 87, #reads = 1077998 mem = 536880704 peak = 1125601280
[M::process] read 683538 sequences (100000056 bp) in 2.463 CPU sec, 2.595 real sec...
sorting block 88, #reads = 1077963 mem = 536878704 peak = 1125601280
[M::process] read 682584 sequences (100000148 bp) in 2.715 CPU sec, 2.905 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 284849, 1, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 215, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 687)
[M::mem_pestat] mean and std.dev: (225.48, 109.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 860)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 343, 486)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1032)
[M::mem_pestat] mean and std.dev: (358.42, 174.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1305)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 264, 385)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 853)
[M::mem_pestat] mean and std.dev: (287.76, 179.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1087)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683538 reads in 100.981 CPU sec, 3.170 real sec
[M::process] read 682138 sequences (100000109 bp) in 1.921 CPU sec, 1.928 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 285678, 1, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 277, 3710)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10746)
[M::mem_pestat] mean and std.dev: (1120.44, 1520.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14264)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 329, 476)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1020)
[M::mem_pestat] mean and std.dev: (349.01, 173.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1292)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 229, 392)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 792)
[M::mem_pestat] mean and std.dev: (276.61, 151.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 992)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 284180, 2, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 214, 314)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 578)
[M::mem_pestat] mean and std.dev: (224.94, 84.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 710)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 350, 491)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1041)
[M::mem_pestat] mean and std.dev: (362.99, 175.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1316)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 406, 1004)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2616)
[M::mem_pestat] mean and std.dev: (472.96, 477.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3422)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681446 sequences (100000165 bp) in 2.193 CPU sec, 2.198 real sec...
[M::mem_process_seqs] Processed 685286 reads in 277.567 CPU sec, 8.786 real sec
[M::mem_process_seqs] Processed 682584 reads in 129.407 CPU sec, 4.098 real sec
sorting block 89, #reads = 1079159 mem = 536881139 peak = 1125601280
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 284304, 4, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 305, 447)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1037)
[M::mem_pestat] mean and std.dev: (273.90, 138.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1332)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 353, 494)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1044)
[M::mem_pestat] mean and std.dev: (365.70, 175.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1319)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 299, 496)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1108)
[M::mem_pestat] mean and std.dev: (308.00, 171.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1414)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680466 sequences (100000141 bp) in 2.665 CPU sec, 2.831 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 283339, 2, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 285, 1307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3587)
[M::mem_pestat] mean and std.dev: (332.50, 300.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4727)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 361, 503)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1061)
[M::mem_pestat] mean and std.dev: (372.14, 177.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1340)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 250, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 775)
[M::mem_pestat] mean and std.dev: (246.56, 118.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 983)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 679550 sequences (100000210 bp) in 1.870 CPU sec, 1.864 real sec...
[M::mem_process_seqs] Processed 682138 reads in 177.226 CPU sec, 5.637 real sec
sorting block 90, #reads = 1079346 mem = 536879409 peak = 1125601280
[M::mem_process_seqs] Processed 681446 reads in 113.353 CPU sec, 3.578 real sec
sorting block 91, #reads = 1077670 mem = 536877838 peak = 1125601280
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (12, 283462, 3, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 281, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 676)
[M::mem_pestat] mean and std.dev: (252.33, 88.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 835)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 365, 503)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1051)
[M::mem_pestat] mean and std.dev: (374.43, 176.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1325)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 271, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 679)
[M::mem_pestat] mean and std.dev: (270.50, 112.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 839)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 679080 sequences (100000127 bp) in 2.552 CPU sec, 2.723 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 282649, 6, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (241, 384, 491)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 991)
[M::mem_pestat] mean and std.dev: (358.90, 143.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1241)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (235, 375, 515)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1075)
[M::mem_pestat] mean and std.dev: (383.54, 180.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1355)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 237, 317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 601)
[M::mem_pestat] mean and std.dev: (235.26, 96.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 743)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 678694 sequences (100000194 bp) in 1.892 CPU sec, 1.895 real sec...
[M::mem_process_seqs] Processed 680466 reads in 176.598 CPU sec, 5.601 real sec
[M::mem_process_seqs] Processed 679550 reads in 112.865 CPU sec, 3.569 real sec
sorting block 92, #reads = 1077128 mem = 536878081 peak = 1125601280
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 282444, 3, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 234, 790)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2046)
[M::mem_pestat] mean and std.dev: (430.04, 499.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2674)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (238, 379, 518)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1078)
[M::mem_pestat] mean and std.dev: (386.69, 180.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1358)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 444, 487)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1039)
[M::mem_pestat] mean and std.dev: (372.40, 163.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1315)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 678950 sequences (100000291 bp) in 2.839 CPU sec, 2.978 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 282422, 1, 14)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 336, 447)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 977)
[M::mem_pestat] mean and std.dev: (311.37, 156.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1242)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (241, 383, 524)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1090)
[M::mem_pestat] mean and std.dev: (390.77, 181.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1373)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 314, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 732)
[M::mem_pestat] mean and std.dev: (263.36, 154.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 931)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 678826 sequences (100000059 bp) in 1.878 CPU sec, 1.883 real sec...
[M::mem_process_seqs] Processed 679080 reads in 174.755 CPU sec, 5.543 real sec
[M::mem_process_seqs] Processed 678694 reads in 111.805 CPU sec, 3.533 real sec
sorting block 93, #reads = 1077432 mem = 536883972 peak = 1125601280
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 282247, 2, 23)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 368, 577)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1349)
[M::mem_pestat] mean and std.dev: (336.48, 184.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1735)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (240, 382, 521)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1083)
[M::mem_pestat] mean and std.dev: (389.23, 181.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1364)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 287, 533)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1175)
[M::mem_pestat] mean and std.dev: (334.19, 164.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1496)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 678996 sequences (100000228 bp) in 2.525 CPU sec, 2.678 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 282836, 0, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (288, 414, 415)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (34, 669)
[M::mem_pestat] mean and std.dev: (338.31, 125.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 840)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (241, 383, 522)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1084)
[M::mem_pestat] mean and std.dev: (389.16, 180.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1365)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 272, 380)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 800)
[M::mem_pestat] mean and std.dev: (262.09, 101.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1010)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 678814 sequences (100000143 bp) in 1.936 CPU sec, 1.941 real sec...
[M::mem_process_seqs] Processed 678950 reads in 173.673 CPU sec, 5.507 real sec
sorting block 94, #reads = 1076519 mem = 536882331 peak = 1125601280
[M::mem_process_seqs] Processed 678826 reads in 110.822 CPU sec, 3.502 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 283059, 3, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 286, 454)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1024)
[M::mem_pestat] mean and std.dev: (299.57, 133.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1309)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (239, 378, 514)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1064)
[M::mem_pestat] mean and std.dev: (384.05, 176.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1339)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 294, 456)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1040)
[M::mem_pestat] mean and std.dev: (276.62, 130.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1332)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 678884 sequences (100000201 bp) in 2.717 CPU sec, 2.837 real sec...
[M::process] read 679200 sequences (100000181 bp) in 1.960 CPU sec, 1.962 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 281939, 0, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (255, 304, 482)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 936)
[M::mem_pestat] mean and std.dev: (313.05, 143.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1163)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (239, 377, 515)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1067)
[M::mem_pestat] mean and std.dev: (384.75, 177.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1343)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (273, 328, 439)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 771)
[M::mem_pestat] mean and std.dev: (333.39, 125.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 937)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 678996 reads in 182.845 CPU sec, 5.801 real sec
sorting block 95, #reads = 1076630 mem = 536879115 peak = 1125601280
[M::mem_process_seqs] Processed 678814 reads in 118.219 CPU sec, 3.738 real sec
sorting block 96, #reads = 1074650 mem = 536881118 peak = 1169092608
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 282817, 2, 21)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 306, 357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 695)
[M::mem_pestat] mean and std.dev: (267.83, 116.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 864)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (239, 379, 514)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1064)
[M::mem_pestat] mean and std.dev: (385.14, 177.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1339)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 287, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 648)
[M::mem_pestat] mean and std.dev: (284.15, 102.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 800)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 679026 sequences (100000255 bp) in 2.474 CPU sec, 2.612 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 282897, 1, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 408, 1092)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2856)
[M::mem_pestat] mean and std.dev: (427.33, 303.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3738)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (239, 379, 515)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1067)
[M::mem_pestat] mean and std.dev: (384.50, 177.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1343)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 236, 345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 633)
[M::mem_pestat] mean and std.dev: (284.45, 128.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 798)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 679328 sequences (100000190 bp) in 1.969 CPU sec, 1.970 real sec...
[M::mem_process_seqs] Processed 678884 reads in 180.080 CPU sec, 5.720 real sec
[M::mem_process_seqs] Processed 679200 reads in 114.824 CPU sec, 3.631 real sec
sorting block 97, #reads = 1074529 mem = 536888753 peak = 1169092608
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 283451, 6, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 272, 431)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 947)
[M::mem_pestat] mean and std.dev: (311.72, 175.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1205)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (239, 378, 513)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1061)
[M::mem_pestat] mean and std.dev: (384.04, 176.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1335)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 331, 493)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1059)
[M::mem_pestat] mean and std.dev: (320.88, 170.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1342)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 678736 sequences (100000005 bp) in 2.744 CPU sec, 2.835 real sec...
[M::process] read 678214 sequences (100000074 bp) in 1.920 CPU sec, 1.925 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 282486, 2, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (238, 356, 528)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1108)
[M::mem_pestat] mean and std.dev: (335.54, 197.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1398)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (235, 372, 511)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1063)
[M::mem_pestat] mean and std.dev: (380.87, 177.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1339)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 342, 431)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 805)
[M::mem_pestat] mean and std.dev: (316.69, 126.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 992)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 679026 reads in 177.228 CPU sec, 5.621 real sec
[M::mem_process_seqs] Processed 679328 reads in 113.146 CPU sec, 3.580 real sec
sorting block 98, #reads = 1075326 mem = 536877498 peak = 1169092608
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 282187, 4, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 317, 410)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 894)
[M::mem_pestat] mean and std.dev: (280.00, 118.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1136)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (239, 380, 518)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1076)
[M::mem_pestat] mean and std.dev: (386.00, 177.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1355)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (320, 352, 712)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1496)
[M::mem_pestat] mean and std.dev: (398.78, 166.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1888)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 678302 sequences (100000233 bp) in 2.517 CPU sec, 2.647 real sec...
[M::process] read 678146 sequences (100000221 bp) in 1.922 CPU sec, 1.929 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 281637, 1, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 238, 285)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 533)
[M::mem_pestat] mean and std.dev: (217.26, 84.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 657)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (242, 380, 516)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1064)
[M::mem_pestat] mean and std.dev: (386.04, 176.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1338)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 269, 413)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 845)
[M::mem_pestat] mean and std.dev: (289.73, 121.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1061)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 678736 reads in 183.412 CPU sec, 5.828 real sec
sorting block 99, #reads = 1075354 mem = 536879208 peak = 1169092608
[M::mem_process_seqs] Processed 678214 reads in 116.283 CPU sec, 3.684 real sec
sorting block 100, #reads = 1074650 mem = 536877917 peak = 1169092608
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 282363, 6, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 244, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 721)
[M::mem_pestat] mean and std.dev: (313.54, 172.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1004)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 382, 518)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1066)
[M::mem_pestat] mean and std.dev: (387.53, 176.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1340)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (289, 372, 541)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1045)
[M::mem_pestat] mean and std.dev: (405.10, 141.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1297)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 677632 sequences (100000288 bp) in 2.799 CPU sec, 2.886 real sec...
[M::process] read 678124 sequences (100000197 bp) in 1.928 CPU sec, 1.933 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 282391, 2, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (143, 255, 345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 749)
[M::mem_pestat] mean and std.dev: (259.11, 141.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 951)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (242, 379, 516)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1064)
[M::mem_pestat] mean and std.dev: (386.15, 176.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1338)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (243, 304, 485)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 969)
[M::mem_pestat] mean and std.dev: (327.34, 168.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1211)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 678302 reads in 180.485 CPU sec, 5.720 real sec
[M::mem_process_seqs] Processed 678146 reads in 114.907 CPU sec, 3.645 real sec
sorting block 101, #reads = 1074889 mem = 536877890 peak = 1169092608
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 281880, 3, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 294, 531)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1159)
[M::mem_pestat] mean and std.dev: (316.23, 144.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1473)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (247, 388, 526)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1084)
[M::mem_pestat] mean and std.dev: (393.48, 178.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1363)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 270, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 674)
[M::mem_pestat] mean and std.dev: (250.52, 120.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 840)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 678276 sequences (100000081 bp) in 2.491 CPU sec, 2.598 real sec...
[M::process] read 677998 sequences (100000293 bp) in 1.910 CPU sec, 1.909 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 282435, 2, 14)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (256, 384, 706)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1606)
[M::mem_pestat] mean and std.dev: (373.93, 183.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2056)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (243, 382, 520)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1074)
[M::mem_pestat] mean and std.dev: (388.84, 177.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1351)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 258, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 570)
[M::mem_pestat] mean and std.dev: (265.00, 85.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 693)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 677632 reads in 184.442 CPU sec, 5.861 real sec
[M::mem_process_seqs] Processed 678124 reads in 117.435 CPU sec, 3.719 real sec
sorting block 102, #reads = 1074465 mem = 536878461 peak = 1169092608
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 282211, 4, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (272, 422, 499)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 953)
[M::mem_pestat] mean and std.dev: (356.82, 141.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1180)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (242, 381, 519)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1073)
[M::mem_pestat] mean and std.dev: (387.48, 177.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1350)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 243, 540)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1260)
[M::mem_pestat] mean and std.dev: (303.68, 173.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1620)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 677296 sequences (100000164 bp) in 2.767 CPU sec, 2.864 real sec...
[M::process] read 677262 sequences (100000198 bp) in 1.921 CPU sec, 1.922 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 281751, 0, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 289, 419)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 901)
[M::mem_pestat] mean and std.dev: (227.87, 88.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1142)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 381, 519)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1069)
[M::mem_pestat] mean and std.dev: (388.05, 177.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1344)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 226, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 560)
[M::mem_pestat] mean and std.dev: (242.62, 69.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 679)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 678276 reads in 181.414 CPU sec, 5.753 real sec
[M::mem_process_seqs] Processed 677998 reads in 114.339 CPU sec, 3.622 real sec
sorting block 103, #reads = 1073954 mem = 536881602 peak = 1169092608
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 281759, 2, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 283, 515)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1113)
[M::mem_pestat] mean and std.dev: (325.15, 190.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1412)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (248, 386, 522)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1070)
[M::mem_pestat] mean and std.dev: (392.01, 177.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1344)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 352, 513)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1151)
[M::mem_pestat] mean and std.dev: (346.53, 150.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1470)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 677714 sequences (100000236 bp) in 2.513 CPU sec, 2.609 real sec...
[M::process] read 676912 sequences (100000194 bp) in 1.801 CPU sec, 1.805 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 281826, 2, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 265, 379)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 717)
[M::mem_pestat] mean and std.dev: (294.24, 133.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 886)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (249, 387, 528)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1086)
[M::mem_pestat] mean and std.dev: (395.31, 180.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1365)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 255, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 642)
[M::mem_pestat] mean and std.dev: (285.21, 105.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 784)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 677296 reads in 181.036 CPU sec, 5.753 real sec
sorting block 104, #reads = 1074299 mem = 536879461 peak = 1169092608
[M::mem_process_seqs] Processed 677262 reads in 113.662 CPU sec, 3.602 real sec
sorting block 105, #reads = 1074560 mem = 536876705 peak = 1169092608
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 282529, 1, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 347, 453)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 923)
[M::mem_pestat] mean and std.dev: (334.32, 140.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1158)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (247, 387, 524)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1078)
[M::mem_pestat] mean and std.dev: (392.86, 179.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1355)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (257, 443, 2265)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6281)
[M::mem_pestat] mean and std.dev: (1121.73, 1369.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8289)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 676938 sequences (100000230 bp) in 2.785 CPU sec, 2.895 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 282608, 5, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 228, 417)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 911)
[M::mem_pestat] mean and std.dev: (238.34, 101.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1158)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (252, 395, 533)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1095)
[M::mem_pestat] mean and std.dev: (400.58, 183.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1376)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 395, 637)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1545)
[M::mem_pestat] mean and std.dev: (375.79, 242.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1999)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 677538 sequences (100000029 bp) in 1.890 CPU sec, 1.884 real sec...
[M::mem_process_seqs] Processed 677714 reads in 175.924 CPU sec, 5.580 real sec
[M::mem_process_seqs] Processed 676912 reads in 110.710 CPU sec, 3.496 real sec
sorting block 106, #reads = 1074475 mem = 536879977 peak = 1169092608
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 282506, 1, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (236, 420, 2589)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7295)
[M::mem_pestat] mean and std.dev: (1469.34, 2127.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9981)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (253, 394, 534)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1096)
[M::mem_pestat] mean and std.dev: (401.52, 184.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1377)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 304, 456)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 952)
[M::mem_pestat] mean and std.dev: (325.15, 159.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1200)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 689228 sequences (100000158 bp) in 2.681 CPU sec, 2.804 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 282694, 9, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (270, 364, 1274)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3282)
[M::mem_pestat] mean and std.dev: (532.28, 682.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4286)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (249, 389, 529)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1089)
[M::mem_pestat] mean and std.dev: (397.06, 183.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1369)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (304, 356, 805)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1807)
[M::mem_pestat] mean and std.dev: (460.30, 229.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2308)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 685304 sequences (100000242 bp) in 1.900 CPU sec, 1.901 real sec...
[M::mem_process_seqs] Processed 676938 reads in 172.261 CPU sec, 5.466 real sec
[M::mem_process_seqs] Processed 677538 reads in 111.686 CPU sec, 3.525 real sec
sorting block 107, #reads = 1075019 mem = 536881948 peak = 1169092608
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 287029, 10, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 252, 426)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 924)
[M::mem_pestat] mean and std.dev: (260.52, 118.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1173)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 300, 438)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 936)
[M::mem_pestat] mean and std.dev: (322.64, 161.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1185)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 1221, 1221)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3361)
[M::mem_pestat] mean and std.dev: (830.00, 524.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4431)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 322, 544)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1286)
[M::mem_pestat] mean and std.dev: (293.48, 153.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1657)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 684504 sequences (100000047 bp) in 2.913 CPU sec, 3.021 real sec...
[M::process] read 683698 sequences (100000186 bp) in 1.994 CPU sec, 1.997 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (22, 285834, 3, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (142, 237, 300)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 616)
[M::mem_pestat] mean and std.dev: (230.55, 88.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 774)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 327, 462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 978)
[M::mem_pestat] mean and std.dev: (342.93, 166.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1236)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 268, 397)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 843)
[M::mem_pestat] mean and std.dev: (284.93, 133.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1066)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 689228 reads in 191.140 CPU sec, 6.064 real sec
sorting block 108, #reads = 1074414 mem = 536879791 peak = 1169092608
[M::mem_process_seqs] Processed 685304 reads in 121.336 CPU sec, 3.846 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 285451, 1, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 221, 421)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 961)
[M::mem_pestat] mean and std.dev: (264.94, 166.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1231)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 333, 469)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 991)
[M::mem_pestat] mean and std.dev: (347.47, 167.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1252)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 290, 430)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 832)
[M::mem_pestat] mean and std.dev: (314.65, 129.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1033)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 683432 sequences (100000128 bp) in 2.712 CPU sec, 2.822 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 285008, 3, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 283, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 646)
[M::mem_pestat] mean and std.dev: (252.71, 88.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 799)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 337, 470)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 988)
[M::mem_pestat] mean and std.dev: (349.88, 167.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1247)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 352, 451)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 917)
[M::mem_pestat] mean and std.dev: (331.19, 127.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1150)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 683694 sequences (100000219 bp) in 1.990 CPU sec, 1.993 real sec...
[M::mem_process_seqs] Processed 684504 reads in 185.353 CPU sec, 5.879 real sec
sorting block 109, #reads = 1075832 mem = 536879101 peak = 1169092608
[M::mem_process_seqs] Processed 683698 reads in 117.908 CPU sec, 3.725 real sec
sorting block 110, #reads = 1074846 mem = 536878395 peak = 1169092608
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (18, 284916, 6, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 250, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 665)
[M::mem_pestat] mean and std.dev: (251.00, 95.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 826)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 339, 472)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 990)
[M::mem_pestat] mean and std.dev: (350.79, 166.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1249)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 374, 501)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1085)
[M::mem_pestat] mean and std.dev: (316.69, 135.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1377)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682636 sequences (100000136 bp) in 2.980 CPU sec, 3.113 real sec...
[M::process] read 682446 sequences (100000158 bp) in 1.989 CPU sec, 1.993 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 284703, 3, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 304, 417)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 925)
[M::mem_pestat] mean and std.dev: (270.17, 118.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1179)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 335, 466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 976)
[M::mem_pestat] mean and std.dev: (347.37, 164.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1231)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 322, 416)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 846)
[M::mem_pestat] mean and std.dev: (339.89, 153.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1061)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683432 reads in 189.930 CPU sec, 6.023 real sec
[M::mem_process_seqs] Processed 683694 reads in 124.414 CPU sec, 3.937 real sec
sorting block 111, #reads = 1074825 mem = 536881541 peak = 1169092608
[M::process] read 681534 sequences (100000053 bp) in 2.475 CPU sec, 2.606 real sec...
[M::process] read 681022 sequences (100000263 bp) in 1.494 CPU sec, 1.504 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 284731, 10, 18)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 201, 265)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 467)
[M::mem_pestat] mean and std.dev: (214.77, 76.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 568)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 346, 478)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 998)
[M::mem_pestat] mean and std.dev: (356.13, 167.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1258)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1126, 1126, 3335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7753)
[M::mem_pestat] mean and std.dev: (2243.70, 1992.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10212)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 241, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 639)
[M::mem_pestat] mean and std.dev: (255.12, 81.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 792)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682446 reads in 105.690 CPU sec, 3.364 real sec
sorting block 112, #reads = 1072307 mem = 536881740 peak = 1169092608
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 285127, 4, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 318, 478)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1016)
[M::mem_pestat] mean and std.dev: (335.10, 185.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1285)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 345, 477)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 997)
[M::mem_pestat] mean and std.dev: (355.50, 167.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1257)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 312, 572)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1340)
[M::mem_pestat] mean and std.dev: (309.48, 157.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1724)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 284681, 8, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 249, 550)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1290)
[M::mem_pestat] mean and std.dev: (310.02, 171.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1660)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 354, 488)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1018)
[M::mem_pestat] mean and std.dev: (363.62, 170.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1283)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (233, 316, 428)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 818)
[M::mem_pestat] mean and std.dev: (298.59, 102.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1013)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682636 reads in 281.231 CPU sec, 8.949 real sec
[M::process] read 680992 sequences (100000165 bp) in 2.104 CPU sec, 2.115 real sec...
[M::mem_process_seqs] Processed 681534 reads in 131.444 CPU sec, 4.186 real sec
sorting block 113, #reads = 1074435 mem = 536880127 peak = 1169092608
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 284492, 1, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (232, 361, 5196)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 15124)
[M::mem_pestat] mean and std.dev: (1964.76, 2829.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 20088)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 357, 492)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1026)
[M::mem_pestat] mean and std.dev: (366.91, 171.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1293)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (266, 387, 520)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1028)
[M::mem_pestat] mean and std.dev: (371.96, 150.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1282)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680872 sequences (100000219 bp) in 2.984 CPU sec, 3.113 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 284264, 6, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 254, 404)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 790)
[M::mem_pestat] mean and std.dev: (253.43, 103.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 983)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 358, 494)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1030)
[M::mem_pestat] mean and std.dev: (368.10, 172.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1298)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 315, 449)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 981)
[M::mem_pestat] mean and std.dev: (333.96, 174.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1247)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680042 sequences (100000063 bp) in 1.850 CPU sec, 1.854 real sec...
[M::mem_process_seqs] Processed 681022 reads in 182.463 CPU sec, 5.788 real sec
[M::mem_process_seqs] Processed 680992 reads in 118.373 CPU sec, 3.744 real sec
sorting block 114, #reads = 1074323 mem = 536878833 peak = 1169092608
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 284278, 1, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 338, 447)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 971)
[M::mem_pestat] mean and std.dev: (293.77, 134.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1233)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 359, 491)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1019)
[M::mem_pestat] mean and std.dev: (366.97, 170.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1283)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 364, 447)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 925)
[M::mem_pestat] mean and std.dev: (355.29, 176.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1164)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680272 sequences (100000000 bp) in 2.863 CPU sec, 3.026 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 283976, 2, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 191, 347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 719)
[M::mem_pestat] mean and std.dev: (244.96, 147.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 905)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (231, 364, 497)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1029)
[M::mem_pestat] mean and std.dev: (371.69, 171.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1295)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 311, 529)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1171)
[M::mem_pestat] mean and std.dev: (334.68, 182.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1492)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681284 sequences (100000275 bp) in 1.920 CPU sec, 1.921 real sec...
[M::mem_process_seqs] Processed 680872 reads in 181.224 CPU sec, 5.744 real sec
sorting block 115, #reads = 1073068 mem = 536881484 peak = 1169092608
[M::mem_process_seqs] Processed 680042 reads in 116.358 CPU sec, 3.678 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 283632, 2, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (122, 195, 231)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 449)
[M::mem_pestat] mean and std.dev: (195.58, 80.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 558)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (231, 364, 498)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1032)
[M::mem_pestat] mean and std.dev: (371.96, 172.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1299)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (262, 288, 350)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (86, 526)
[M::mem_pestat] mean and std.dev: (279.62, 70.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 614)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 679910 sequences (100000217 bp) in 2.798 CPU sec, 2.924 real sec...
[M::process] read 678814 sequences (100000201 bp) in 1.920 CPU sec, 1.929 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 284134, 3, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (109, 268, 355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 847)
[M::mem_pestat] mean and std.dev: (245.59, 138.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1093)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 355, 494)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1036)
[M::mem_pestat] mean and std.dev: (366.63, 173.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1307)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 350, 503)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1053)
[M::mem_pestat] mean and std.dev: (348.61, 159.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1328)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680272 reads in 184.748 CPU sec, 5.863 real sec
sorting block 116, #reads = 1074974 mem = 536880815 peak = 1169092608
[M::mem_process_seqs] Processed 681284 reads in 117.064 CPU sec, 3.704 real sec
sorting block 117, #reads = 1073174 mem = 536878434 peak = 1169092608
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 282948, 5, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 298, 379)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 825)
[M::mem_pestat] mean and std.dev: (270.78, 146.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1048)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (233, 367, 501)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1037)
[M::mem_pestat] mean and std.dev: (375.07, 173.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1305)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (257, 361, 533)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1085)
[M::mem_pestat] mean and std.dev: (360.91, 147.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1361)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 679350 sequences (100000180 bp) in 2.919 CPU sec, 3.115 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 283032, 3, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 252, 327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 619)
[M::mem_pestat] mean and std.dev: (255.64, 105.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 765)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (239, 377, 516)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1070)
[M::mem_pestat] mean and std.dev: (385.68, 179.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1347)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 282, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 714)
[M::mem_pestat] mean and std.dev: (256.79, 104.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 890)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 679458 sequences (100000278 bp) in 1.870 CPU sec, 1.863 real sec...
[M::mem_process_seqs] Processed 679910 reads in 180.197 CPU sec, 5.711 real sec
[M::mem_process_seqs] Processed 678814 reads in 116.411 CPU sec, 3.684 real sec
sorting block 118, #reads = 1073961 mem = 536878726 peak = 1169092608
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 283319, 3, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (230, 293, 644)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1472)
[M::mem_pestat] mean and std.dev: (417.70, 349.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1886)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (236, 371, 510)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1058)
[M::mem_pestat] mean and std.dev: (380.85, 177.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1332)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 406, 656)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1480)
[M::mem_pestat] mean and std.dev: (398.40, 184.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1892)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 678024 sequences (100000293 bp) in 2.526 CPU sec, 2.677 real sec...
[M::process] read 677598 sequences (100000200 bp) in 1.911 CPU sec, 1.919 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 283796, 1, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (108, 169, 293)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 663)
[M::mem_pestat] mean and std.dev: (185.56, 91.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 848)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (235, 374, 517)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1081)
[M::mem_pestat] mean and std.dev: (384.54, 181.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1363)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 419, 810)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2058)
[M::mem_pestat] mean and std.dev: (459.41, 349.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2682)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 679350 reads in 178.147 CPU sec, 5.652 real sec
[M::mem_process_seqs] Processed 679458 reads in 112.161 CPU sec, 3.556 real sec
sorting block 119, #reads = 1074755 mem = 536876961 peak = 1169092608
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 282413, 8, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (143, 461, 478)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1148)
[M::mem_pestat] mean and std.dev: (317.27, 160.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1483)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (246, 388, 529)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1095)
[M::mem_pestat] mean and std.dev: (394.56, 182.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1378)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 231, 426)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 930)
[M::mem_pestat] mean and std.dev: (277.77, 150.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1182)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 677636 sequences (100000257 bp) in 2.994 CPU sec, 3.150 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 282569, 1, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (228, 328, 542)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1170)
[M::mem_pestat] mean and std.dev: (291.42, 134.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1484)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (248, 391, 533)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1103)
[M::mem_pestat] mean and std.dev: (398.69, 184.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1388)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (144, 350, 424)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 984)
[M::mem_pestat] mean and std.dev: (319.76, 162.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1264)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 677584 sequences (100000187 bp) in 1.940 CPU sec, 1.936 real sec...
[M::mem_process_seqs] Processed 678024 reads in 179.470 CPU sec, 5.687 real sec
sorting block 120, #reads = 1076397 mem = 536879911 peak = 1169092608
[M::mem_process_seqs] Processed 677598 reads in 115.888 CPU sec, 3.657 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 282476, 2, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (250, 262, 419)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 757)
[M::mem_pestat] mean and std.dev: (301.82, 126.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 926)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (247, 393, 538)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1120)
[M::mem_pestat] mean and std.dev: (401.05, 187.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1411)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 280, 512)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1138)
[M::mem_pestat] mean and std.dev: (274.63, 126.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1451)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 121, #reads = 1074014 mem = 536878611 peak = 1169092608
[M::process] read 677578 sequences (100000109 bp) in 2.872 CPU sec, 2.988 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 282448, 1, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (130, 220, 380)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 880)
[M::mem_pestat] mean and std.dev: (252.30, 146.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1130)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (248, 394, 540)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1124)
[M::mem_pestat] mean and std.dev: (402.26, 187.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1416)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (121, 215, 854)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2320)
[M::mem_pestat] mean and std.dev: (361.91, 359.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3053)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 677204 sequences (100000247 bp) in 1.926 CPU sec, 1.931 real sec...
[M::mem_process_seqs] Processed 677636 reads in 177.113 CPU sec, 5.620 real sec
[M::mem_process_seqs] Processed 677584 reads in 112.571 CPU sec, 3.559 real sec
sorting block 122, #reads = 1073932 mem = 536880120 peak = 1169092608
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 283186, 2, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (235, 485, 578)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1264)
[M::mem_pestat] mean and std.dev: (393.53, 169.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1607)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (248, 393, 537)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1115)
[M::mem_pestat] mean and std.dev: (400.91, 187.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1404)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 254, 383)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 837)
[M::mem_pestat] mean and std.dev: (270.86, 147.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1064)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 677084 sequences (100000217 bp) in 2.394 CPU sec, 2.528 real sec...
[M::process] read 676792 sequences (100000202 bp) in 1.433 CPU sec, 1.440 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 282444, 4, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 283, 383)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 755)
[M::mem_pestat] mean and std.dev: (298.45, 135.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 941)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (251, 393, 536)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1106)
[M::mem_pestat] mean and std.dev: (401.52, 186.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1391)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (278, 458, 485)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 899)
[M::mem_pestat] mean and std.dev: (399.46, 183.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1133)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 677578 reads in 172.795 CPU sec, 5.501 real sec
[M::mem_process_seqs] Processed 677204 reads in 112.195 CPU sec, 3.580 real sec
sorting block 123, #reads = 1075211 mem = 536880345 peak = 1169092608
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 283127, 5, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 306, 420)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 824)
[M::mem_pestat] mean and std.dev: (278.49, 111.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1026)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (254, 400, 541)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1115)
[M::mem_pestat] mean and std.dev: (406.07, 188.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1402)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (285, 334, 477)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 861)
[M::mem_pestat] mean and std.dev: (349.09, 129.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1053)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 677642 sequences (100000156 bp) in 2.671 CPU sec, 2.791 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 283140, 1, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (228, 259, 556)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1212)
[M::mem_pestat] mean and std.dev: (277.71, 124.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1540)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (255, 401, 547)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1131)
[M::mem_pestat] mean and std.dev: (409.62, 190.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1423)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (266, 362, 521)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1031)
[M::mem_pestat] mean and std.dev: (370.04, 152.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1286)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682470 sequences (100000272 bp) in 1.910 CPU sec, 1.907 real sec...
[M::mem_process_seqs] Processed 677084 reads in 179.495 CPU sec, 5.705 real sec
[M::mem_process_seqs] Processed 676792 reads in 113.364 CPU sec, 3.590 real sec
sorting block 124, #reads = 1072712 mem = 536878066 peak = 1169092608
[M::process] read 683004 sequences (100000009 bp) in 2.517 CPU sec, 2.675 real sec...
[M::process] read 681856 sequences (100000170 bp) in 1.411 CPU sec, 1.414 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 284235, 0, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (259, 317, 416)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 730)
[M::mem_pestat] mean and std.dev: (324.00, 128.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 887)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 352, 495)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1047)
[M::mem_pestat] mean and std.dev: (367.04, 179.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1323)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (260, 355, 506)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 998)
[M::mem_pestat] mean and std.dev: (341.50, 128.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1244)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682470 reads in 108.989 CPU sec, 3.481 real sec
sorting block 125, #reads = 1072003 mem = 536878641 peak = 1169092608
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 283029, 0, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 439, 841)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2113)
[M::mem_pestat] mean and std.dev: (433.84, 293.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2749)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (248, 392, 535)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1109)
[M::mem_pestat] mean and std.dev: (400.72, 187.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1396)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 286, 437)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 893)
[M::mem_pestat] mean and std.dev: (283.12, 109.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1121)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (22, 284881, 2, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 232, 668)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1626)
[M::mem_pestat] mean and std.dev: (266.50, 157.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2105)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 345, 490)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1040)
[M::mem_pestat] mean and std.dev: (362.81, 179.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1315)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (277, 331, 512)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 982)
[M::mem_pestat] mean and std.dev: (323.90, 126.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1217)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681508 sequences (100000231 bp) in 2.065 CPU sec, 2.077 real sec...
[M::mem_process_seqs] Processed 677642 reads in 290.265 CPU sec, 9.250 real sec
[M::mem_process_seqs] Processed 683004 reads in 135.831 CPU sec, 4.340 real sec
sorting block 126, #reads = 1071187 mem = 536880961 peak = 1169092608
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 284317, 5, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (232, 296, 421)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 799)
[M::mem_pestat] mean and std.dev: (323.82, 134.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 988)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 354, 494)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1040)
[M::mem_pestat] mean and std.dev: (368.29, 178.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1313)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 254, 690)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1726)
[M::mem_pestat] mean and std.dev: (265.29, 164.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2244)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681088 sequences (100000265 bp) in 3.003 CPU sec, 3.183 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (22, 284060, 1, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 256, 300)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 552)
[M::mem_pestat] mean and std.dev: (228.32, 80.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 678)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 354, 492)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1030)
[M::mem_pestat] mean and std.dev: (367.42, 176.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1299)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 404, 514)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1186)
[M::mem_pestat] mean and std.dev: (414.11, 260.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1522)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681856 reads in 168.021 CPU sec, 5.327 real sec
[M::process] read 680644 sequences (100000260 bp) in 1.850 CPU sec, 1.844 real sec...
sorting block 127, #reads = 1076805 mem = 536878466 peak = 1169092608
[M::mem_process_seqs] Processed 681508 reads in 109.138 CPU sec, 3.448 real sec
sorting block 128, #reads = 1078702 mem = 536878717 peak = 1169092608
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 283467, 2, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 317, 436)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 940)
[M::mem_pestat] mean and std.dev: (326.32, 186.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1192)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 357, 496)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1038)
[M::mem_pestat] mean and std.dev: (370.01, 176.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1309)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 286, 561)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1293)
[M::mem_pestat] mean and std.dev: (286.18, 142.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1659)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680116 sequences (100000046 bp) in 2.436 CPU sec, 2.582 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 283905, 4, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 281, 776)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1982)
[M::mem_pestat] mean and std.dev: (385.82, 291.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2585)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 362, 501)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1047)
[M::mem_pestat] mean and std.dev: (374.32, 178.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1320)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 304, 396)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 748)
[M::mem_pestat] mean and std.dev: (302.58, 134.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 924)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 679896 sequences (100000078 bp) in 1.910 CPU sec, 1.917 real sec...
[M::mem_process_seqs] Processed 681088 reads in 168.242 CPU sec, 5.337 real sec
[M::mem_process_seqs] Processed 680644 reads in 106.730 CPU sec, 3.373 real sec
sorting block 129, #reads = 1078940 mem = 536882755 peak = 1169092608
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 283469, 4, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 287, 457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1049)
[M::mem_pestat] mean and std.dev: (258.54, 131.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1345)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (232, 366, 505)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1051)
[M::mem_pestat] mean and std.dev: (377.84, 178.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1324)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 303, 498)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1050)
[M::mem_pestat] mean and std.dev: (336.17, 180.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1326)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 679670 sequences (100000220 bp) in 2.686 CPU sec, 2.798 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 283674, 0, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 266, 316)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 638)
[M::mem_pestat] mean and std.dev: (239.35, 105.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 799)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (234, 371, 511)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1065)
[M::mem_pestat] mean and std.dev: (382.33, 181.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1342)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 286, 422)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 864)
[M::mem_pestat] mean and std.dev: (285.73, 121.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1085)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 679508 sequences (100000236 bp) in 1.848 CPU sec, 1.852 real sec...
[M::mem_process_seqs] Processed 680116 reads in 166.701 CPU sec, 5.293 real sec
[M::mem_process_seqs] Processed 679896 reads in 107.419 CPU sec, 3.395 real sec
sorting block 130, #reads = 1079306 mem = 536877074 peak = 1169092608
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 283343, 1, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 330, 408)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 826)
[M::mem_pestat] mean and std.dev: (295.04, 126.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1035)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (235, 374, 517)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1081)
[M::mem_pestat] mean and std.dev: (385.09, 183.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1363)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 240, 378)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 782)
[M::mem_pestat] mean and std.dev: (266.10, 132.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 984)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 679084 sequences (100000126 bp) in 2.404 CPU sec, 2.542 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (22, 282977, 8, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (145, 207, 283)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 559)
[M::mem_pestat] mean and std.dev: (211.10, 71.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 697)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (237, 374, 513)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1065)
[M::mem_pestat] mean and std.dev: (384.65, 182.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1341)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 302, 456)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 918)
[M::mem_pestat] mean and std.dev: (316.27, 149.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1149)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 679488 sequences (100000270 bp) in 1.920 CPU sec, 1.917 real sec...
[M::mem_process_seqs] Processed 679670 reads in 170.122 CPU sec, 5.401 real sec
[M::mem_process_seqs] Processed 679508 reads in 109.063 CPU sec, 3.445 real sec
sorting block 131, #reads = 1078672 mem = 536878452 peak = 1169092608
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 283247, 2, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (244, 328, 462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 898)
[M::mem_pestat] mean and std.dev: (333.68, 136.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1116)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (238, 377, 518)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1078)
[M::mem_pestat] mean and std.dev: (387.62, 183.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1358)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (242, 304, 639)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1433)
[M::mem_pestat] mean and std.dev: (406.91, 232.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1830)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 679130 sequences (100000061 bp) in 2.707 CPU sec, 2.817 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 283362, 1, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 209, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 782)
[M::mem_pestat] mean and std.dev: (252.38, 131.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 991)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (237, 374, 513)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1065)
[M::mem_pestat] mean and std.dev: (383.97, 180.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1341)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (255, 350, 1254)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3252)
[M::mem_pestat] mean and std.dev: (458.81, 354.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4251)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 679604 sequences (100000223 bp) in 1.880 CPU sec, 1.886 real sec...
[M::mem_process_seqs] Processed 679084 reads in 168.881 CPU sec, 5.358 real sec
sorting block 132, #reads = 1078429 mem = 536878907 peak = 1169092608
[M::mem_process_seqs] Processed 679488 reads in 108.930 CPU sec, 3.443 real sec
sorting block 133, #reads = 1079285 mem = 536884207 peak = 1169092608
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 283295, 3, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 274, 353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 661)
[M::mem_pestat] mean and std.dev: (282.87, 117.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 815)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (238, 375, 514)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1066)
[M::mem_pestat] mean and std.dev: (385.07, 180.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1342)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 270, 445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 909)
[M::mem_pestat] mean and std.dev: (279.21, 133.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1141)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 678970 sequences (100000245 bp) in 2.403 CPU sec, 2.514 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 283785, 5, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (223, 314, 391)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 727)
[M::mem_pestat] mean and std.dev: (278.25, 98.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 895)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (234, 370, 507)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1053)
[M::mem_pestat] mean and std.dev: (379.89, 178.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1326)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 297, 486)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1124)
[M::mem_pestat] mean and std.dev: (278.00, 142.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1443)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 678482 sequences (100000057 bp) in 1.915 CPU sec, 1.922 real sec...
[M::mem_process_seqs] Processed 679130 reads in 176.147 CPU sec, 5.601 real sec
[M::mem_process_seqs] Processed 679604 reads in 112.362 CPU sec, 3.556 real sec
sorting block 134, #reads = 1077552 mem = 536877650 peak = 1169092608
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 282884, 0, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 320, 513)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1107)
[M::mem_pestat] mean and std.dev: (324.35, 145.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1404)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (239, 377, 516)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1070)
[M::mem_pestat] mean and std.dev: (386.67, 181.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1347)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 250, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 733)
[M::mem_pestat] mean and std.dev: (268.51, 116.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 917)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 678134 sequences (100000113 bp) in 2.744 CPU sec, 2.849 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 282784, 0, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 193, 357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 753)
[M::mem_pestat] mean and std.dev: (226.09, 124.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 951)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (242, 379, 516)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1064)
[M::mem_pestat] mean and std.dev: (388.43, 181.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1338)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (248, 382, 608)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1328)
[M::mem_pestat] mean and std.dev: (356.87, 217.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1688)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 678316 sequences (100000229 bp) in 1.920 CPU sec, 1.925 real sec...
[M::mem_process_seqs] Processed 678970 reads in 174.222 CPU sec, 5.525 real sec
[M::mem_process_seqs] Processed 678482 reads in 111.919 CPU sec, 3.540 real sec
sorting block 135, #reads = 1076365 mem = 536878574 peak = 1169092608
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 282532, 5, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 366, 410)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 836)
[M::mem_pestat] mean and std.dev: (312.84, 156.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1049)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 378, 515)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1057)
[M::mem_pestat] mean and std.dev: (387.89, 179.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1328)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 288, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 762)
[M::mem_pestat] mean and std.dev: (281.68, 143.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 960)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 678304 sequences (100000087 bp) in 2.471 CPU sec, 2.590 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 282771, 0, 22)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 275, 393)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 869)
[M::mem_pestat] mean and std.dev: (320.35, 198.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1114)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 384, 523)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1081)
[M::mem_pestat] mean and std.dev: (392.71, 183.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1360)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (253, 437, 535)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1099)
[M::mem_pestat] mean and std.dev: (359.15, 148.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1381)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 677698 sequences (100000086 bp) in 1.910 CPU sec, 1.906 real sec...
[M::mem_process_seqs] Processed 678134 reads in 167.443 CPU sec, 5.307 real sec
[M::mem_process_seqs] Processed 678316 reads in 106.973 CPU sec, 3.377 real sec
sorting block 136, #reads = 1076425 mem = 536878624 peak = 1169092608
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 282553, 0, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 231, 671)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1653)
[M::mem_pestat] mean and std.dev: (355.90, 297.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2144)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 384, 525)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1087)
[M::mem_pestat] mean and std.dev: (393.14, 183.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1368)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (290, 346, 532)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1016)
[M::mem_pestat] mean and std.dev: (346.31, 122.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1258)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 677600 sequences (100000059 bp) in 2.555 CPU sec, 2.649 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 282565, 1, 21)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 269, 419)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 937)
[M::mem_pestat] mean and std.dev: (300.77, 170.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1196)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (248, 388, 530)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1094)
[M::mem_pestat] mean and std.dev: (398.08, 185.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1376)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (230, 246, 323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (44, 509)
[M::mem_pestat] mean and std.dev: (247.79, 60.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 602)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 677714 sequences (100000239 bp) in 1.888 CPU sec, 1.896 real sec...
[M::mem_process_seqs] Processed 678304 reads in 169.901 CPU sec, 5.390 real sec
sorting block 137, #reads = 1075929 mem = 536879406 peak = 1169092608
[M::mem_process_seqs] Processed 677698 reads in 110.368 CPU sec, 3.493 real sec
sorting block 138, #reads = 1076138 mem = 536882799 peak = 1169092608
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 282451, 0, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (269, 272, 351)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (105, 515)
[M::mem_pestat] mean and std.dev: (260.51, 72.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 597)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (250, 390, 530)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1090)
[M::mem_pestat] mean and std.dev: (398.71, 185.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1370)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 381, 758)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1884)
[M::mem_pestat] mean and std.dev: (327.33, 186.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2447)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 677684 sequences (100000259 bp) in 2.524 CPU sec, 2.632 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 282179, 1, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 295, 469)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1083)
[M::mem_pestat] mean and std.dev: (280.53, 157.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1390)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (247, 387, 526)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1084)
[M::mem_pestat] mean and std.dev: (395.36, 183.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1363)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 201, 287)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 501)
[M::mem_pestat] mean and std.dev: (220.23, 79.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 608)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 677452 sequences (100000155 bp) in 1.910 CPU sec, 1.910 real sec...
[M::mem_process_seqs] Processed 677600 reads in 178.169 CPU sec, 5.663 real sec
[M::mem_process_seqs] Processed 677714 reads in 113.127 CPU sec, 3.575 real sec
sorting block 139, #reads = 1075494 mem = 536883552 peak = 1169092608
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 282560, 5, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 274, 405)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 799)
[M::mem_pestat] mean and std.dev: (285.92, 114.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 996)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (246, 387, 530)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1098)
[M::mem_pestat] mean and std.dev: (396.87, 185.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1382)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (274, 399, 573)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1171)
[M::mem_pestat] mean and std.dev: (351.65, 161.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1470)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 677834 sequences (100000156 bp) in 2.674 CPU sec, 2.782 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 282259, 0, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 331, 415)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 849)
[M::mem_pestat] mean and std.dev: (262.03, 93.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1066)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (249, 389, 530)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1092)
[M::mem_pestat] mean and std.dev: (398.30, 184.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1373)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 328, 436)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 888)
[M::mem_pestat] mean and std.dev: (313.55, 128.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1114)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 677706 sequences (100000088 bp) in 1.877 CPU sec, 1.879 real sec...
[M::mem_process_seqs] Processed 677684 reads in 175.302 CPU sec, 5.562 real sec
[M::mem_process_seqs] Processed 677452 reads in 111.099 CPU sec, 3.515 real sec
sorting block 140, #reads = 1075639 mem = 536879258 peak = 1169092608
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 282935, 5, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 307, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 655)
[M::mem_pestat] mean and std.dev: (263.95, 124.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 813)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (246, 383, 523)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1077)
[M::mem_pestat] mean and std.dev: (392.46, 181.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1354)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 249, 406)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 798)
[M::mem_pestat] mean and std.dev: (261.40, 92.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 994)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 677648 sequences (100000130 bp) in 2.542 CPU sec, 2.665 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 282426, 5, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 352, 533)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1169)
[M::mem_pestat] mean and std.dev: (385.96, 247.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1487)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (247, 389, 533)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1105)
[M::mem_pestat] mean and std.dev: (398.44, 186.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1391)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 298, 412)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 870)
[M::mem_pestat] mean and std.dev: (296.79, 147.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1099)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 677696 sequences (100000253 bp) in 1.867 CPU sec, 1.875 real sec...
[M::mem_process_seqs] Processed 677834 reads in 173.855 CPU sec, 5.527 real sec
sorting block 141, #reads = 1075208 mem = 536881760 peak = 1169092608
[M::mem_process_seqs] Processed 677706 reads in 111.127 CPU sec, 3.509 real sec
sorting block 142, #reads = 1075332 mem = 536878636 peak = 1169092608
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 282982, 3, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 251, 483)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1109)
[M::mem_pestat] mean and std.dev: (265.22, 143.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1422)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (247, 387, 529)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1093)
[M::mem_pestat] mean and std.dev: (397.03, 185.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1375)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (236, 416, 549)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1175)
[M::mem_pestat] mean and std.dev: (411.34, 224.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1488)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 677462 sequences (100000118 bp) in 2.547 CPU sec, 2.643 real sec...
[M::process] read 677946 sequences (100000239 bp) in 1.811 CPU sec, 1.812 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 282949, 2, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 188, 253)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 463)
[M::mem_pestat] mean and std.dev: (190.11, 63.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 568)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (245, 386, 529)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1097)
[M::mem_pestat] mean and std.dev: (395.47, 184.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1381)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (277, 432, 641)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1369)
[M::mem_pestat] mean and std.dev: (393.88, 166.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1733)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 677648 reads in 175.080 CPU sec, 5.559 real sec
[M::mem_process_seqs] Processed 677696 reads in 112.194 CPU sec, 3.556 real sec
sorting block 143, #reads = 1074932 mem = 536880169 peak = 1169092608
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 282784, 1, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 256, 437)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 965)
[M::mem_pestat] mean and std.dev: (260.54, 138.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1229)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (247, 389, 536)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1114)
[M::mem_pestat] mean and std.dev: (399.78, 187.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1403)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 433, 476)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 940)
[M::mem_pestat] mean and std.dev: (367.39, 161.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1172)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 677694 sequences (100000059 bp) in 2.439 CPU sec, 2.528 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 283194, 7, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 280, 317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (5, 525)
[M::mem_pestat] mean and std.dev: (261.78, 78.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 629)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (245, 386, 531)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1103)
[M::mem_pestat] mean and std.dev: (397.58, 188.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1389)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (304, 332, 415)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (82, 637)
[M::mem_pestat] mean and std.dev: (333.00, 106.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 757)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 677152 sequences (100000021 bp) in 1.970 CPU sec, 1.965 real sec...
[M::mem_process_seqs] Processed 677462 reads in 173.386 CPU sec, 5.499 real sec
[M::mem_process_seqs] Processed 677946 reads in 112.376 CPU sec, 3.555 real sec
sorting block 144, #reads = 1073773 mem = 536879538 peak = 1169092608
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 283641, 0, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 174, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 731)
[M::mem_pestat] mean and std.dev: (221.21, 111.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 925)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (245, 385, 527)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1091)
[M::mem_pestat] mean and std.dev: (395.82, 186.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1373)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 278, 420)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 872)
[M::mem_pestat] mean and std.dev: (302.32, 133.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1098)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 679656 sequences (100000010 bp) in 2.784 CPU sec, 2.871 real sec...
[M::process] read 688294 sequences (100000002 bp) in 1.520 CPU sec, 1.522 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 282006, 1, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 416, 3019)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8639)
[M::mem_pestat] mean and std.dev: (1661.79, 2088.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11449)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (251, 392, 539)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1115)
[M::mem_pestat] mean and std.dev: (404.95, 191.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1403)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 253, 488)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1086)
[M::mem_pestat] mean and std.dev: (342.74, 223.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1385)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 677694 reads in 163.302 CPU sec, 5.181 real sec
[M::mem_process_seqs] Processed 677152 reads in 98.034 CPU sec, 3.102 real sec
sorting block 145, #reads = 1074633 mem = 536876930 peak = 1169092608
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 283054, 0, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 279, 368)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 670)
[M::mem_pestat] mean and std.dev: (263.59, 103.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 821)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (235, 377, 527)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1111)
[M::mem_pestat] mean and std.dev: (392.36, 192.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1403)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 302, 428)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 796)
[M::mem_pestat] mean and std.dev: (318.86, 134.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 980)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 686376 sequences (100000114 bp) in 2.075 CPU sec, 2.155 real sec...
[M::process] read 684600 sequences (100000103 bp) in 1.490 CPU sec, 1.496 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 286828, 5, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (230, 323, 452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 896)
[M::mem_pestat] mean and std.dev: (294.91, 111.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1118)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 307, 446)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 952)
[M::mem_pestat] mean and std.dev: (328.63, 164.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1205)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 275, 356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 654)
[M::mem_pestat] mean and std.dev: (261.63, 95.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 803)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 679656 reads in 161.403 CPU sec, 5.133 real sec
sorting block 146, #reads = 1070118 mem = 536878470 peak = 1169092608
[M::mem_process_seqs] Processed 688294 reads in 103.688 CPU sec, 3.305 real sec
sorting block 147, #reads = 1069074 mem = 536877186 peak = 1169092608
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 286477, 1, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (141, 239, 403)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 927)
[M::mem_pestat] mean and std.dev: (237.08, 119.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1189)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 320, 458)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 974)
[M::mem_pestat] mean and std.dev: (338.31, 166.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1232)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 354, 460)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 936)
[M::mem_pestat] mean and std.dev: (362.51, 162.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1174)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 683664 sequences (100000082 bp) in 2.728 CPU sec, 2.793 real sec...
[M::process] read 682750 sequences (100000297 bp) in 1.788 CPU sec, 1.797 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 285570, 2, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 274, 1613)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4507)
[M::mem_pestat] mean and std.dev: (563.03, 556.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5954)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 331, 467)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 987)
[M::mem_pestat] mean and std.dev: (345.92, 166.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1247)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 296, 430)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 884)
[M::mem_pestat] mean and std.dev: (261.34, 96.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1111)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 686376 reads in 183.114 CPU sec, 5.811 real sec
[M::mem_process_seqs] Processed 684600 reads in 118.365 CPU sec, 3.761 real sec
sorting block 148, #reads = 1075236 mem = 536879598 peak = 1169092608
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 285496, 3, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 322, 382)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 772)
[M::mem_pestat] mean and std.dev: (279.71, 118.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 967)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 336, 470)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 988)
[M::mem_pestat] mean and std.dev: (348.99, 166.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1247)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 333, 434)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 864)
[M::mem_pestat] mean and std.dev: (349.91, 151.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1079)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682360 sequences (100000260 bp) in 2.513 CPU sec, 2.607 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 284818, 16, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (251, 350, 492)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 974)
[M::mem_pestat] mean and std.dev: (340.75, 145.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1215)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 340, 470)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 978)
[M::mem_pestat] mean and std.dev: (351.83, 165.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1232)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (620, 722, 3447)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9101)
[M::mem_pestat] mean and std.dev: (1316.62, 1239.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11928)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 315, 399)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 771)
[M::mem_pestat] mean and std.dev: (322.36, 136.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 957)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682168 sequences (100000016 bp) in 1.920 CPU sec, 1.924 real sec...
[M::mem_process_seqs] Processed 683664 reads in 177.558 CPU sec, 5.642 real sec
[M::mem_process_seqs] Processed 682750 reads in 114.607 CPU sec, 3.621 real sec
sorting block 149, #reads = 1074163 mem = 536878734 peak = 1169092608
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (21, 284927, 2, 21)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 322, 494)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1100)
[M::mem_pestat] mean and std.dev: (331.26, 205.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1403)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 347, 481)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1007)
[M::mem_pestat] mean and std.dev: (358.16, 169.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1270)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 312, 682)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1674)
[M::mem_pestat] mean and std.dev: (358.89, 214.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2170)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681010 sequences (100000143 bp) in 2.621 CPU sec, 2.697 real sec...
[M::process] read 680794 sequences (100000058 bp) in 1.966 CPU sec, 1.967 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 283881, 6, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 236, 411)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 827)
[M::mem_pestat] mean and std.dev: (282.49, 133.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1035)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 351, 488)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1024)
[M::mem_pestat] mean and std.dev: (362.83, 172.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1292)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 348, 386)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 728)
[M::mem_pestat] mean and std.dev: (292.40, 103.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 899)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682360 reads in 184.869 CPU sec, 5.864 real sec
[M::mem_process_seqs] Processed 682168 reads in 123.933 CPU sec, 3.935 real sec
sorting block 150, #reads = 1073065 mem = 536879173 peak = 1169092608
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 283948, 3, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (130, 254, 465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1135)
[M::mem_pestat] mean and std.dev: (254.11, 130.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1470)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 359, 496)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1038)
[M::mem_pestat] mean and std.dev: (368.64, 173.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1309)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (230, 303, 527)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1121)
[M::mem_pestat] mean and std.dev: (367.43, 190.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1418)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680434 sequences (100000218 bp) in 2.508 CPU sec, 2.599 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 284063, 4, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 237, 471)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 985)
[M::mem_pestat] mean and std.dev: (271.04, 108.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1242)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 361, 498)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1042)
[M::mem_pestat] mean and std.dev: (370.56, 173.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1314)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (231, 285, 397)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 729)
[M::mem_pestat] mean and std.dev: (312.49, 132.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 895)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680238 sequences (100000084 bp) in 1.940 CPU sec, 1.932 real sec...
[M::mem_process_seqs] Processed 681010 reads in 177.564 CPU sec, 5.640 real sec
sorting block 151, #reads = 1072076 mem = 536876956 peak = 1169092608
[M::mem_process_seqs] Processed 680794 reads in 113.599 CPU sec, 3.597 real sec
sorting block 152, #reads = 1073604 mem = 536878447 peak = 1169092608
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 283787, 2, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 336, 613)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1413)
[M::mem_pestat] mean and std.dev: (328.75, 196.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1813)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (230, 366, 504)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1052)
[M::mem_pestat] mean and std.dev: (374.77, 175.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1326)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 318, 432)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 902)
[M::mem_pestat] mean and std.dev: (316.53, 152.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1137)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681086 sequences (100000096 bp) in 2.857 CPU sec, 2.934 real sec...
[M::process] read 679716 sequences (100000056 bp) in 1.636 CPU sec, 1.644 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 283803, 0, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (239, 375, 421)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 785)
[M::mem_pestat] mean and std.dev: (339.81, 120.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 967)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 363, 500)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1042)
[M::mem_pestat] mean and std.dev: (372.64, 174.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1313)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (139, 313, 417)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 973)
[M::mem_pestat] mean and std.dev: (287.54, 125.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1251)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680434 reads in 180.059 CPU sec, 5.724 real sec
[M::mem_process_seqs] Processed 680238 reads in 115.894 CPU sec, 3.671 real sec
sorting block 153, #reads = 1073981 mem = 536880163 peak = 1169092608
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (22, 284332, 3, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (140, 300, 532)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1316)
[M::mem_pestat] mean and std.dev: (303.24, 174.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1708)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 354, 487)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1013)
[M::mem_pestat] mean and std.dev: (363.38, 168.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1276)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 247, 295)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 545)
[M::mem_pestat] mean and std.dev: (253.43, 112.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 703)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 678426 sequences (100000008 bp) in 2.565 CPU sec, 2.668 real sec...
[M::process] read 678718 sequences (100000132 bp) in 1.940 CPU sec, 1.940 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 283788, 3, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 338, 490)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1176)
[M::mem_pestat] mean and std.dev: (335.06, 257.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1519)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (233, 366, 501)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1037)
[M::mem_pestat] mean and std.dev: (374.45, 173.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1305)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 304, 447)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 991)
[M::mem_pestat] mean and std.dev: (299.19, 155.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1263)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681086 reads in 184.672 CPU sec, 5.869 real sec
[M::mem_process_seqs] Processed 679716 reads in 118.345 CPU sec, 3.753 real sec
sorting block 154, #reads = 1073404 mem = 536878573 peak = 1169092608
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 283445, 0, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 364, 537)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1275)
[M::mem_pestat] mean and std.dev: (310.85, 160.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1644)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (242, 378, 511)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1049)
[M::mem_pestat] mean and std.dev: (384.89, 175.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1318)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 295, 477)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 993)
[M::mem_pestat] mean and std.dev: (326.56, 145.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1251)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 679434 sequences (100000178 bp) in 2.847 CPU sec, 2.924 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 282572, 3, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (145, 257, 472)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1126)
[M::mem_pestat] mean and std.dev: (289.31, 206.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1453)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (240, 374, 508)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1044)
[M::mem_pestat] mean and std.dev: (381.65, 174.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1312)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 335, 510)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1170)
[M::mem_pestat] mean and std.dev: (367.53, 207.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1500)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 679092 sequences (100000070 bp) in 2.050 CPU sec, 2.052 real sec...
[M::mem_process_seqs] Processed 678426 reads in 181.105 CPU sec, 5.740 real sec
sorting block 155, #reads = 1073082 mem = 536878606 peak = 1169092608
[M::mem_process_seqs] Processed 678718 reads in 116.943 CPU sec, 3.690 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 283333, 1, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 200, 279)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 493)
[M::mem_pestat] mean and std.dev: (210.18, 68.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 600)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (233, 367, 503)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1043)
[M::mem_pestat] mean and std.dev: (374.82, 172.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1313)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 263, 408)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 916)
[M::mem_pestat] mean and std.dev: (236.07, 100.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1170)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 156, #reads = 1072940 mem = 536881313 peak = 1169092608
[M::process] read 678732 sequences (100000121 bp) in 2.232 CPU sec, 2.352 real sec...
[M::process] read 678740 sequences (100000142 bp) in 1.440 CPU sec, 1.440 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 283018, 1, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 220, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 610)
[M::mem_pestat] mean and std.dev: (227.14, 86.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 754)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (235, 369, 505)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1045)
[M::mem_pestat] mean and std.dev: (377.61, 173.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1315)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (249, 392, 639)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1419)
[M::mem_pestat] mean and std.dev: (400.62, 201.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1809)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 679434 reads in 163.860 CPU sec, 5.219 real sec
[M::mem_process_seqs] Processed 679092 reads in 104.529 CPU sec, 3.323 real sec
sorting block 157, #reads = 1072905 mem = 536877589 peak = 1169092608
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 282403, 0, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (256, 366, 571)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1201)
[M::mem_pestat] mean and std.dev: (374.13, 169.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1516)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (237, 371, 509)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1053)
[M::mem_pestat] mean and std.dev: (380.17, 175.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1325)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 279, 459)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1021)
[M::mem_pestat] mean and std.dev: (334.13, 207.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1302)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 678482 sequences (100000112 bp) in 2.719 CPU sec, 2.808 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 282707, 1, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 400, 587)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1413)
[M::mem_pestat] mean and std.dev: (395.92, 247.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1826)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (238, 373, 508)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1048)
[M::mem_pestat] mean and std.dev: (381.04, 175.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1318)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (253, 315, 419)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 751)
[M::mem_pestat] mean and std.dev: (310.02, 113.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 917)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 678704 sequences (100000161 bp) in 1.840 CPU sec, 1.846 real sec...
[M::mem_process_seqs] Processed 678732 reads in 175.215 CPU sec, 5.563 real sec
[M::mem_process_seqs] Processed 678740 reads in 108.908 CPU sec, 3.433 real sec
sorting block 158, #reads = 1073513 mem = 536877847 peak = 1169092608
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 282236, 2, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (126, 176, 356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 816)
[M::mem_pestat] mean and std.dev: (220.84, 135.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1046)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (239, 373, 510)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1052)
[M::mem_pestat] mean and std.dev: (381.93, 175.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1323)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 292, 476)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1000)
[M::mem_pestat] mean and std.dev: (308.74, 136.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1262)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 678378 sequences (100000162 bp) in 2.415 CPU sec, 2.485 real sec...
[M::process] read 678174 sequences (100000242 bp) in 1.860 CPU sec, 1.861 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 282543, 0, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (141, 217, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 696)
[M::mem_pestat] mean and std.dev: (241.28, 115.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 881)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (239, 373, 511)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1055)
[M::mem_pestat] mean and std.dev: (382.63, 177.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1327)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 287, 387)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 797)
[M::mem_pestat] mean and std.dev: (265.36, 112.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1002)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 678482 reads in 169.600 CPU sec, 5.380 real sec
[M::mem_process_seqs] Processed 678704 reads in 106.994 CPU sec, 3.383 real sec
sorting block 159, #reads = 1074881 mem = 536885880 peak = 1169092608
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 282226, 3, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 240, 410)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 868)
[M::mem_pestat] mean and std.dev: (233.34, 96.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1097)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (241, 378, 517)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1069)
[M::mem_pestat] mean and std.dev: (386.91, 179.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1345)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (249, 378, 528)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1086)
[M::mem_pestat] mean and std.dev: (339.76, 140.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1365)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 678232 sequences (100000067 bp) in 2.668 CPU sec, 2.716 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 282527, 1, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 288, 524)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1178)
[M::mem_pestat] mean and std.dev: (333.26, 194.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1505)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (242, 381, 522)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1082)
[M::mem_pestat] mean and std.dev: (389.74, 181.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1362)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 326, 501)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1125)
[M::mem_pestat] mean and std.dev: (361.97, 211.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1437)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 678234 sequences (100000092 bp) in 1.850 CPU sec, 1.853 real sec...
[M::mem_process_seqs] Processed 678378 reads in 166.974 CPU sec, 5.288 real sec
sorting block 160, #reads = 1075208 mem = 536885095 peak = 1169092608
[M::mem_process_seqs] Processed 678174 reads in 104.269 CPU sec, 3.298 real sec
sorting block 161, #reads = 1075352 mem = 536877315 peak = 1169092608
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 282728, 0, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 353, 442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 884)
[M::mem_pestat] mean and std.dev: (332.86, 151.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1105)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (242, 380, 521)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1079)
[M::mem_pestat] mean and std.dev: (389.09, 180.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1358)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 290, 476)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1088)
[M::mem_pestat] mean and std.dev: (299.75, 165.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1394)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 677660 sequences (100000026 bp) in 2.425 CPU sec, 2.479 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 282321, 1, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (241, 270, 521)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1081)
[M::mem_pestat] mean and std.dev: (373.63, 223.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1361)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (242, 381, 523)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1085)
[M::mem_pestat] mean and std.dev: (390.34, 181.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1366)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 276, 434)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 908)
[M::mem_pestat] mean and std.dev: (293.97, 127.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1145)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 676358 sequences (100000151 bp) in 1.780 CPU sec, 1.786 real sec...
[M::mem_process_seqs] Processed 678232 reads in 160.105 CPU sec, 5.076 real sec
[M::mem_process_seqs] Processed 678234 reads in 100.739 CPU sec, 3.185 real sec
sorting block 162, #reads = 1074188 mem = 536877231 peak = 1169092608
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 281954, 0, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 280, 535)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1179)
[M::mem_pestat] mean and std.dev: (316.89, 176.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1501)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (246, 387, 529)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1095)
[M::mem_pestat] mean and std.dev: (396.24, 184.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1378)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 344, 375)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 675)
[M::mem_pestat] mean and std.dev: (295.50, 103.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 825)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 677342 sequences (100000222 bp) in 2.647 CPU sec, 2.703 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 282544, 1, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 337, 599)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1413)
[M::mem_pestat] mean and std.dev: (362.59, 274.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1820)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (259, 403, 546)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1120)
[M::mem_pestat] mean and std.dev: (409.91, 187.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1407)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (246, 428, 555)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1173)
[M::mem_pestat] mean and std.dev: (377.90, 202.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1482)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 677742 sequences (100000041 bp) in 1.870 CPU sec, 1.869 real sec...
[M::mem_process_seqs] Processed 677660 reads in 156.754 CPU sec, 4.954 real sec
[M::mem_process_seqs] Processed 676358 reads in 97.349 CPU sec, 3.069 real sec
sorting block 163, #reads = 1074269 mem = 536879399 peak = 1169092608
[M::process] read 126942 sequences (18700281 bp) in 0.688 CPU sec, 0.694 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 282485, 1, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 259, 354)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 668)
[M::mem_pestat] mean and std.dev: (283.96, 133.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 825)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (248, 388, 531)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1097)
[M::mem_pestat] mean and std.dev: (398.20, 185.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1380)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (248, 325, 443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 833)
[M::mem_pestat] mean and std.dev: (344.65, 141.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1028)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 282396, 2, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 303, 516)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1166)
[M::mem_pestat] mean and std.dev: (279.96, 172.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1491)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (245, 384, 525)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1085)
[M::mem_pestat] mean and std.dev: (394.04, 183.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1365)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 310, 403)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 789)
[M::mem_pestat] mean and std.dev: (254.65, 106.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 982)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (9, 52972, 2, 4)
[M::mem_pestat] skip orientation FF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (235, 369, 507)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1051)
[M::mem_pestat] mean and std.dev: (379.72, 177.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1323)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] skip orientation RR as there are not enough pairs
[M::mem_process_seqs] Processed 677342 reads in 164.773 CPU sec, 5.328 real sec
[M::mem_process_seqs] Processed 677742 reads in 110.022 CPU sec, 3.550 real sec
sorting block 164, #reads = 1074141 mem = 536878891 peak = 1169092608
[M::mem_process_seqs] Processed 126942 reads in 113.218 CPU sec, 3.663 real sec
sorting block 165, #reads = 1073975 mem = 536879442 peak = 1218940928
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000a06d1
  features: 1f8bfbff fffab20b
  extended: f1bf27eb 1b407f7e
  amd bits: 2c100800 00000121
     brand: Intel(R) Xeon(R) 6975P-C
threads: 31
algo: bwa-mem
license: sentieon:klib=31
reads: 177935798
overall: 69913452544 mem 26572.340 user 553.785 sys 883.951 real
[main] Version: 0.7.17-r1188
[main] CMD: /opt/conda/share/sentieon-202308.03-3/libexec/bwa mem -K 100000000 -Y -R @RG\tID:A23MHWWLT4.1136_3LU-T1-TDNA-1_A23MHWWLT4_1.L007\tPU:L007\tSM:1136_3LU-T1-TDNA-1_A23MHWWLT4_1\tLB:1136_3LU-T1-TDNA-1_A23MHWWLT4_1\tDS:s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta\tPL:ILLUMINA -t 31 ./BWAIndex/Homo_sapiens_assembly38.fasta.64 1136_3LU-T1-TDNA-1_A23MHWWLT4_1_R1.fastq.gz 1136_3LU-T1-TDNA-1_A23MHWWLT4_1_R2.fastq.gz
[main] Real time: 883.994 sec; CPU: 27126.128 sec
sorting block 166, #reads = 54398 mem = 27273561 peak = 1218940928
uniq header count 1
merging 167 blocks
sw version: sentieon-genomics-202308.03
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000a06d1
  features: 1f8bfbff fffab20b
  extended: f1bf27eb 1b407f7e
  amd bits: 2c100800 00000121
     brand: Intel(R) Xeon(R) 6975P-C
threads: 31 max 192
algo: util-sort
license: sentieon:util=1
output file size: 10314950833
output reads: 178901605
bam_mem_sort: 167 calls 103.177 user 1.423 sys 106.233 real
bam_write: 167 calls 66.722 user 3.788 sys 108.101 real
execute: 1 calls 40.872 user 1.541 sys 946.970 real
merge_files: 1 calls 40.859 user 1.511 sys 62.914 real
parse_chunk: 2657 calls 121.071 user 28.912 sys 167.026 real
read_chunk: 7162 calls 53.098 user 44.647 sys 827.202 real
sort_block: 1 calls 38.532 user 43.996 sys 803.562 real
write_chunk: 4503 calls 40.529 user 1.193 sys 61.976 real
overall: 3307966464 mem 2492.362 user 98.245 sys 946.995 real
ls: cannot access '*.cram': No such file or directory