.command.log - Workdir - DAQ:SENTIEON_BWAMEM (1136_4ZB-T1-TDNA-1_A23MHWWLT4_1;L002;0001)

File Info

Filename: .command.log
Full Path: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/69/2e17bc4e2c54d6c60a5b4627909e72/.command.log
Size: 247.8 KB
Task: DAQ:SENTIEON_BWAMEM (1136_4ZB-T1-TDNA-1_A23MHWWLT4_1;L002;0001)
Attempt
Content

  Downloading: s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/69/2e17bc4e2c54d6c60a5b4627909e72/.command.sh
  Downloading: s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta.fai
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/ac/6dc6cc86c065da607df208f73a1f56/1136_4ZB-T1-TDNA-1_A23MHWWLT4_1/1136_4ZB-T1-TDNA-1_A23MHWWLT4_1_R1.fastq.gz
  Downloading: s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/BWAIndex
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/69/2e17bc4e2c54d6c60a5b4627909e72/.command.run
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/ac/6dc6cc86c065da607df208f73a1f56/1136_4ZB-T1-TDNA-1_A23MHWWLT4_1/1136_4ZB-T1-TDNA-1_A23MHWWLT4_1_R2.fastq.gz
==> STAGING COMPLETE (7 inputs)

This software is licensed to bgold@natera.com by Sentieon Inc.
cmdline: /opt/conda/share/sentieon-202308.03-3/libexec/util sort -r Homo_sapiens_assembly38.fasta -t 31 -o 1136_4ZB-T1-TDNA-1_A23MHWWLT4_1.bam --sam2bam -
This software is licensed to bgold@natera.com by Sentieon Inc.
version: sentieon-genomics-202308.03
[M::bwa_idx_load_from_disk] read 3171 ALT contigs
[M::main_mem] bwa index loaded in 1925.864 CPU sec, 69.440 real sec
[M::process] read 706898 sequences (100000145 bp) in 0.995 CPU sec, 1.003 real sec...
[M::process] read 705404 sequences (100000076 bp) in 1.547 CPU sec, 1.665 real sec...
[M::process] read 704588 sequences (100000029 bp) in 1.596 CPU sec, 1.595 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 288465, 18, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 285, 515)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1181)
[M::mem_pestat] mean and std.dev: (314.50, 182.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1514)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 217, 313)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 641)
[M::mem_pestat] mean and std.dev: (240.15, 117.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 805)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (546, 1375, 2216)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5556)
[M::mem_pestat] mean and std.dev: (1636.83, 1469.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7516)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 288, 467)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1061)
[M::mem_pestat] mean and std.dev: (335.82, 220.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1358)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704458 sequences (100000019 bp) in 1.570 CPU sec, 1.567 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (76, 288423, 16, 74)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 304, 540)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1316)
[M::mem_pestat] mean and std.dev: (321.17, 215.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1704)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 220, 319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 657)
[M::mem_pestat] mean and std.dev: (243.96, 119.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 826)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (70, 216, 660)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1840)
[M::mem_pestat] mean and std.dev: (264.21, 237.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2430)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 253, 389)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 749)
[M::mem_pestat] mean and std.dev: (285.79, 129.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 929)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 288526, 14, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 279, 472)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1072)
[M::mem_pestat] mean and std.dev: (291.84, 173.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1372)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 222, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 662)
[M::mem_pestat] mean and std.dev: (246.00, 120.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 832)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (46, 592, 1203)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3517)
[M::mem_pestat] mean and std.dev: (648.71, 618.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4674)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 343, 2065)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5857)
[M::mem_pestat] mean and std.dev: (1010.36, 1192.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7753)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 706898 reads in 286.007 CPU sec, 9.234 real sec
[M::mem_process_seqs] Processed 705404 reads in 199.197 CPU sec, 6.456 real sec
[M::mem_process_seqs] Processed 704588 reads in 218.832 CPU sec, 7.091 real sec
sorting block 0, #reads = 1085780 mem = 536878923 peak = 573272064
[M::process] read 704034 sequences (100000070 bp) in 2.338 CPU sec, 2.478 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 288221, 19, 78)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 256, 376)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 790)
[M::mem_pestat] mean and std.dev: (261.78, 140.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 997)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 223, 323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 667)
[M::mem_pestat] mean and std.dev: (246.80, 121.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 839)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (472, 1164, 1871)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4669)
[M::mem_pestat] mean and std.dev: (1102.72, 757.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6068)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 283, 459)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1005)
[M::mem_pestat] mean and std.dev: (311.39, 178.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1278)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703232 sequences (100000225 bp) in 1.889 CPU sec, 1.928 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 288351, 19, 75)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 230, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 669)
[M::mem_pestat] mean and std.dev: (252.75, 117.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 833)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 224, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 668)
[M::mem_pestat] mean and std.dev: (248.15, 122.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 840)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (697, 697, 1445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2941)
[M::mem_pestat] mean and std.dev: (1095.79, 920.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4778)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 336, 810)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2056)
[M::mem_pestat] mean and std.dev: (489.49, 473.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2679)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703270 sequences (100000188 bp) in 1.616 CPU sec, 1.619 real sec...
[M::mem_process_seqs] Processed 704458 reads in 189.305 CPU sec, 6.004 real sec
sorting block 1, #reads = 1085695 mem = 536878160 peak = 820211712
[M::mem_process_seqs] Processed 704034 reads in 124.629 CPU sec, 3.951 real sec
sorting block 2, #reads = 1084691 mem = 536880076 peak = 896462848
[M::process] read 702872 sequences (100000146 bp) in 2.112 CPU sec, 2.212 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (77, 288105, 18, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 258, 724)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1784)
[M::mem_pestat] mean and std.dev: (459.88, 450.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2314)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 225, 327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 675)
[M::mem_pestat] mean and std.dev: (249.64, 123.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 849)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (260, 386, 1087)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2741)
[M::mem_pestat] mean and std.dev: (460.50, 362.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3568)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 252, 630)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1502)
[M::mem_pestat] mean and std.dev: (311.53, 262.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1938)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703304 sequences (100000221 bp) in 1.746 CPU sec, 1.766 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 288574, 24, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (141, 218, 421)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 981)
[M::mem_pestat] mean and std.dev: (270.37, 176.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1261)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 226, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 678)
[M::mem_pestat] mean and std.dev: (250.15, 123.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 853)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (876, 1504, 2133)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4647)
[M::mem_pestat] mean and std.dev: (1415.83, 915.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5904)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 331, 524)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1210)
[M::mem_pestat] mean and std.dev: (339.67, 221.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1553)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 287970, 26, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 243, 422)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 876)
[M::mem_pestat] mean and std.dev: (266.05, 150.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1103)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 226, 327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 673)
[M::mem_pestat] mean and std.dev: (250.10, 123.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 846)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (403, 695, 2159)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5671)
[M::mem_pestat] mean and std.dev: (1271.46, 1206.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7427)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 322, 954)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2530)
[M::mem_pestat] mean and std.dev: (436.48, 480.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3318)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703232 reads in 257.219 CPU sec, 8.211 real sec
[M::mem_process_seqs] Processed 703270 reads in 194.069 CPU sec, 6.224 real sec
[M::mem_process_seqs] Processed 702872 reads in 213.645 CPU sec, 6.881 real sec
sorting block 3, #reads = 1085002 mem = 536882557 peak = 896462848
[M::process] read 703328 sequences (100000036 bp) in 2.610 CPU sec, 2.775 real sec...
sorting block 4, #reads = 1084265 mem = 536883172 peak = 896462848
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 288332, 30, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 267, 482)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1112)
[M::mem_pestat] mean and std.dev: (296.55, 204.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1427)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 225, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 669)
[M::mem_pestat] mean and std.dev: (248.68, 122.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 841)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (462, 977, 1569)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3783)
[M::mem_pestat] mean and std.dev: (1011.58, 778.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4890)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 299, 497)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1089)
[M::mem_pestat] mean and std.dev: (338.25, 232.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1385)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703120 sequences (100000105 bp) in 1.751 CPU sec, 1.783 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 287534, 24, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 293, 755)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1875)
[M::mem_pestat] mean and std.dev: (392.80, 342.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2435)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 224, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 666)
[M::mem_pestat] mean and std.dev: (247.83, 121.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 837)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (407, 1102, 1755)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4451)
[M::mem_pestat] mean and std.dev: (1026.95, 886.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5799)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 311, 779)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1973)
[M::mem_pestat] mean and std.dev: (473.91, 399.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2570)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702476 sequences (100000109 bp) in 1.480 CPU sec, 1.487 real sec...
[M::mem_process_seqs] Processed 703304 reads in 189.875 CPU sec, 6.085 real sec
[M::mem_process_seqs] Processed 703328 reads in 122.460 CPU sec, 3.878 real sec
sorting block 5, #reads = 1084709 mem = 536878452 peak = 896462848
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 287179, 26, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (138, 197, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 738)
[M::mem_pestat] mean and std.dev: (229.90, 131.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 938)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 224, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 666)
[M::mem_pestat] mean and std.dev: (247.95, 121.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 837)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 372, 928)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2486)
[M::mem_pestat] mean and std.dev: (480.35, 514.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3265)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 279, 750)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1884)
[M::mem_pestat] mean and std.dev: (454.69, 427.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2451)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702004 sequences (100000289 bp) in 2.455 CPU sec, 2.580 real sec...
[M::process] read 701352 sequences (100000197 bp) in 1.769 CPU sec, 1.771 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 288151, 25, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 279, 1700)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4758)
[M::mem_pestat] mean and std.dev: (835.90, 1136.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6287)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 226, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 667)
[M::mem_pestat] mean and std.dev: (249.44, 122.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 838)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (225, 901, 2334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6552)
[M::mem_pestat] mean and std.dev: (1089.78, 1110.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8661)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 250, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 653)
[M::mem_pestat] mean and std.dev: (257.14, 103.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 810)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703120 reads in 186.321 CPU sec, 5.981 real sec
[M::mem_process_seqs] Processed 702476 reads in 119.082 CPU sec, 3.788 real sec
sorting block 6, #reads = 1084528 mem = 536881350 peak = 896462848
[M::process] read 701774 sequences (100000285 bp) in 2.090 CPU sec, 2.194 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 287031, 21, 79)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 271, 450)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 988)
[M::mem_pestat] mean and std.dev: (278.79, 165.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1257)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 227, 327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 671)
[M::mem_pestat] mean and std.dev: (250.35, 122.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 843)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (120, 693, 1169)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3267)
[M::mem_pestat] mean and std.dev: (603.15, 587.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4316)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 273, 421)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 925)
[M::mem_pestat] mean and std.dev: (297.68, 178.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1177)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701412 sequences (100000062 bp) in 1.774 CPU sec, 1.783 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 287182, 22, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 252, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 671)
[M::mem_pestat] mean and std.dev: (237.33, 115.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 838)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 230, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 681)
[M::mem_pestat] mean and std.dev: (253.03, 123.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 856)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (318, 636, 1229)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3051)
[M::mem_pestat] mean and std.dev: (812.52, 662.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3962)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 250, 714)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1718)
[M::mem_pestat] mean and std.dev: (469.25, 404.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2220)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702004 reads in 180.648 CPU sec, 5.751 real sec
sorting block 7, #reads = 1084040 mem = 536878402 peak = 896462848
[M::mem_process_seqs] Processed 701352 reads in 117.662 CPU sec, 3.967 real sec
sorting block 8, #reads = 1083102 mem = 536878818 peak = 896462848
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 287329, 25, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 217, 603)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1487)
[M::mem_pestat] mean and std.dev: (353.64, 328.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1929)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 229, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 674)
[M::mem_pestat] mean and std.dev: (251.66, 122.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 847)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (426, 595, 1238)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2862)
[M::mem_pestat] mean and std.dev: (737.14, 531.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3674)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 262, 461)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1075)
[M::mem_pestat] mean and std.dev: (284.69, 187.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1382)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701016 sequences (100000077 bp) in 2.445 CPU sec, 2.587 real sec...
[M::process] read 700504 sequences (100000087 bp) in 1.777 CPU sec, 1.781 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 287031, 27, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 267, 860)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2254)
[M::mem_pestat] mean and std.dev: (439.87, 451.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2951)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 229, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 672)
[M::mem_pestat] mean and std.dev: (251.15, 121.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 844)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (589, 1176, 1732)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4018)
[M::mem_pestat] mean and std.dev: (1235.60, 761.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5161)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 244, 385)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 835)
[M::mem_pestat] mean and std.dev: (266.98, 153.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1060)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701774 reads in 186.092 CPU sec, 6.144 real sec
[M::mem_process_seqs] Processed 701412 reads in 119.189 CPU sec, 3.866 real sec
sorting block 9, #reads = 1082952 mem = 536884152 peak = 896462848
[M::process] read 700984 sequences (100000010 bp) in 2.119 CPU sec, 2.227 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 287293, 18, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 309, 571)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1299)
[M::mem_pestat] mean and std.dev: (363.27, 277.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1663)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 231, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 676)
[M::mem_pestat] mean and std.dev: (252.93, 122.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 849)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (346, 681, 1519)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3865)
[M::mem_pestat] mean and std.dev: (760.44, 569.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5038)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 291, 497)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1079)
[M::mem_pestat] mean and std.dev: (280.10, 133.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1370)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701016 reads in 102.281 CPU sec, 3.381 real sec
sorting block 10, #reads = 1082977 mem = 536877482 peak = 896462848
[M::process] read 706036 sequences (100000047 bp) in 2.048 CPU sec, 2.153 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 287616, 16, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 290, 405)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 895)
[M::mem_pestat] mean and std.dev: (280.81, 161.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1140)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 232, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 688)
[M::mem_pestat] mean and std.dev: (255.01, 124.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 865)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (360, 866, 1433)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3579)
[M::mem_pestat] mean and std.dev: (853.80, 633.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4652)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 245, 595)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1417)
[M::mem_pestat] mean and std.dev: (319.13, 233.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1828)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705544 sequences (100000266 bp) in 1.975 CPU sec, 1.984 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 287171, 18, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 259, 489)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1151)
[M::mem_pestat] mean and std.dev: (299.21, 208.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1482)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 230, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 681)
[M::mem_pestat] mean and std.dev: (253.32, 123.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 856)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (282, 859, 1055)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2601)
[M::mem_pestat] mean and std.dev: (657.12, 377.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3374)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 374, 774)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1976)
[M::mem_pestat] mean and std.dev: (417.20, 326.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2577)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700504 reads in 202.321 CPU sec, 6.472 real sec
[M::mem_process_seqs] Processed 700984 reads in 218.939 CPU sec, 7.112 real sec
sorting block 11, #reads = 1082925 mem = 536877968 peak = 896462848
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 288663, 18, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 253, 458)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1054)
[M::mem_pestat] mean and std.dev: (295.75, 176.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1352)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 218, 316)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 650)
[M::mem_pestat] mean and std.dev: (242.35, 119.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 817)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (308, 638, 1113)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2723)
[M::mem_pestat] mean and std.dev: (618.38, 484.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3528)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 288, 449)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 971)
[M::mem_pestat] mean and std.dev: (306.38, 154.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1232)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704476 sequences (100000147 bp) in 2.619 CPU sec, 2.782 real sec...
[M::process] read 704246 sequences (100000296 bp) in 1.830 CPU sec, 1.821 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 288325, 25, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 341, 522)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1234)
[M::mem_pestat] mean and std.dev: (333.25, 218.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1590)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 221, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 663)
[M::mem_pestat] mean and std.dev: (244.95, 120.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 834)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (233, 714, 2442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6860)
[M::mem_pestat] mean and std.dev: (1359.88, 1736.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9069)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 276, 388)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 844)
[M::mem_pestat] mean and std.dev: (235.46, 115.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1072)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 706036 reads in 189.725 CPU sec, 6.121 real sec
[M::mem_process_seqs] Processed 705544 reads in 120.855 CPU sec, 3.843 real sec
sorting block 12, #reads = 1085274 mem = 536879162 peak = 896462848
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 288040, 18, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 289, 592)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1390)
[M::mem_pestat] mean and std.dev: (391.71, 262.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1789)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 222, 323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 667)
[M::mem_pestat] mean and std.dev: (246.80, 122.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 839)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 674, 815)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2113)
[M::mem_pestat] mean and std.dev: (381.93, 286.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2762)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 264, 382)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 758)
[M::mem_pestat] mean and std.dev: (260.50, 101.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 946)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703810 sequences (100000146 bp) in 2.548 CPU sec, 2.667 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 288348, 15, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 294, 1530)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4232)
[M::mem_pestat] mean and std.dev: (729.38, 819.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5583)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 224, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 671)
[M::mem_pestat] mean and std.dev: (248.50, 123.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 844)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (253, 400, 1311)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3427)
[M::mem_pestat] mean and std.dev: (630.00, 630.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4485)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (239, 287, 534)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1124)
[M::mem_pestat] mean and std.dev: (308.66, 141.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1419)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703618 sequences (100000094 bp) in 2.103 CPU sec, 2.102 real sec...
[M::mem_process_seqs] Processed 704476 reads in 180.142 CPU sec, 5.803 real sec
sorting block 13, #reads = 1086493 mem = 536879345 peak = 896462848
[M::mem_process_seqs] Processed 704246 reads in 112.446 CPU sec, 3.581 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 287788, 14, 72)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 338, 615)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1523)
[M::mem_pestat] mean and std.dev: (377.43, 323.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1977)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 225, 327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 677)
[M::mem_pestat] mean and std.dev: (249.50, 123.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 852)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (133, 838, 1114)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3076)
[M::mem_pestat] mean and std.dev: (695.17, 615.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4057)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 289, 453)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1019)
[M::mem_pestat] mean and std.dev: (296.35, 151.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1302)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 14, #reads = 1086804 mem = 536877127 peak = 896462848
[M::process] read 702840 sequences (100000006 bp) in 2.481 CPU sec, 2.611 real sec...
[M::process] read 702762 sequences (100000080 bp) in 1.401 CPU sec, 1.407 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 288460, 15, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 280, 551)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1307)
[M::mem_pestat] mean and std.dev: (301.63, 198.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1685)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 225, 327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 675)
[M::mem_pestat] mean and std.dev: (249.96, 124.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 849)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (664, 1916, 2208)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5296)
[M::mem_pestat] mean and std.dev: (1510.93, 1096.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6840)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 258, 413)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 867)
[M::mem_pestat] mean and std.dev: (299.00, 184.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1094)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703810 reads in 174.804 CPU sec, 5.594 real sec
[M::mem_process_seqs] Processed 703618 reads in 114.442 CPU sec, 3.646 real sec
sorting block 15, #reads = 1085806 mem = 536879607 peak = 896462848
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 287521, 17, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 219, 312)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 574)
[M::mem_pestat] mean and std.dev: (234.23, 100.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 705)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 226, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 679)
[M::mem_pestat] mean and std.dev: (251.07, 124.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 854)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 335, 943)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2441)
[M::mem_pestat] mean and std.dev: (294.43, 253.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3190)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 299, 704)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1710)
[M::mem_pestat] mean and std.dev: (399.51, 301.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2213)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703088 sequences (100000201 bp) in 2.350 CPU sec, 2.472 real sec...
[M::process] read 703622 sequences (100000298 bp) in 1.457 CPU sec, 1.454 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 287864, 35, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 248, 419)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 925)
[M::mem_pestat] mean and std.dev: (263.12, 149.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1178)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 226, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 676)
[M::mem_pestat] mean and std.dev: (250.95, 124.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 850)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (588, 938, 1566)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3522)
[M::mem_pestat] mean and std.dev: (1026.75, 611.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4500)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 241, 424)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 956)
[M::mem_pestat] mean and std.dev: (307.11, 191.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1222)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702840 reads in 169.338 CPU sec, 5.397 real sec
[M::process] read 703788 sequences (100000258 bp) in 1.923 CPU sec, 1.928 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 287713, 30, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 426, 634)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1482)
[M::mem_pestat] mean and std.dev: (413.52, 270.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1906)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 225, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 669)
[M::mem_pestat] mean and std.dev: (248.71, 122.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 841)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (247, 280, 743)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1735)
[M::mem_pestat] mean and std.dev: (425.71, 344.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2231)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 252, 450)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 966)
[M::mem_pestat] mean and std.dev: (297.07, 164.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1224)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703088 reads in 101.882 CPU sec, 3.251 real sec
sorting block 16, #reads = 1085249 mem = 536877541 peak = 896462848
[M::mem_process_seqs] Processed 702762 reads in 242.599 CPU sec, 7.756 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 287589, 19, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 277, 1068)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2808)
[M::mem_pestat] mean and std.dev: (512.48, 547.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3678)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 223, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 668)
sorting block 17, #reads = 1083454 mem = 536880409 peak = 953364480
[M::mem_pestat] mean and std.dev: (248.04, 122.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 840)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (225, 806, 4187)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12111)
[M::mem_pestat] mean and std.dev: (1645.47, 1680.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 16073)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 460, 1517)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4113)
[M::mem_pestat] mean and std.dev: (752.80, 791.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5411)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703316 sequences (100000181 bp) in 2.390 CPU sec, 2.602 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 288705, 25, 76)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 242, 583)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1391)
[M::mem_pestat] mean and std.dev: (353.73, 281.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1795)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 223, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 668)
[M::mem_pestat] mean and std.dev: (248.05, 122.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 840)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (528, 776, 1900)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4644)
[M::mem_pestat] mean and std.dev: (1015.67, 730.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6016)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (231, 321, 461)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 921)
[M::mem_pestat] mean and std.dev: (316.76, 151.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1151)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702582 sequences (100000035 bp) in 1.710 CPU sec, 1.718 real sec...
[M::mem_process_seqs] Processed 703622 reads in 193.724 CPU sec, 6.157 real sec
[M::mem_process_seqs] Processed 703788 reads in 119.861 CPU sec, 3.798 real sec
sorting block 18, #reads = 1083972 mem = 536878720 peak = 953364480
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (81, 287909, 35, 83)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 215, 454)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1064)
[M::mem_pestat] mean and std.dev: (269.28, 183.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1369)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 225, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 666)
[M::mem_pestat] mean and std.dev: (248.40, 121.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 837)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (617, 907, 3133)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8165)
[M::mem_pestat] mean and std.dev: (1611.77, 1604.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10681)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 252, 418)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 904)
[M::mem_pestat] mean and std.dev: (268.45, 139.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1147)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702574 sequences (100000103 bp) in 2.280 CPU sec, 2.406 real sec...
[M::process] read 702672 sequences (100000133 bp) in 1.549 CPU sec, 1.553 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 287470, 19, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 425, 931)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2371)
[M::mem_pestat] mean and std.dev: (661.00, 617.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3133)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 225, 323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 663)
[M::mem_pestat] mean and std.dev: (248.16, 121.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 833)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (468, 489, 3787)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10425)
[M::mem_pestat] mean and std.dev: (1581.58, 1694.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13744)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 274, 923)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2391)
[M::mem_pestat] mean and std.dev: (499.33, 503.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3125)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703316 reads in 172.755 CPU sec, 5.496 real sec
sorting block 19, #reads = 1084102 mem = 536877706 peak = 953364480
[M::mem_process_seqs] Processed 702582 reads in 114.597 CPU sec, 3.867 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 287306, 15, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 277, 507)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1153)
[M::mem_pestat] mean and std.dev: (299.24, 191.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1476)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 226, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 670)
[M::mem_pestat] mean and std.dev: (249.72, 122.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 842)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (644, 779, 978)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1646)
[M::mem_pestat] mean and std.dev: (710.71, 406.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2336)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 283, 447)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 969)
[M::mem_pestat] mean and std.dev: (302.26, 185.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1230)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702330 sequences (100000069 bp) in 2.548 CPU sec, 2.677 real sec...
[M::process] read 701748 sequences (100000119 bp) in 1.860 CPU sec, 1.858 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 287598, 20, 80)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 261, 1045)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2831)
[M::mem_pestat] mean and std.dev: (536.21, 632.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3724)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 226, 327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 673)
[M::mem_pestat] mean and std.dev: (250.27, 123.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 846)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (370, 686, 4367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12361)
[M::mem_pestat] mean and std.dev: (1977.25, 2326.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 16358)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 254, 388)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 794)
[M::mem_pestat] mean and std.dev: (272.59, 136.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 997)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702574 reads in 176.232 CPU sec, 5.810 real sec
sorting block 20, #reads = 1084486 mem = 536880791 peak = 953364480
[M::mem_process_seqs] Processed 702672 reads in 114.574 CPU sec, 3.718 real sec
sorting block 21, #reads = 1083604 mem = 536878275 peak = 953364480
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 287801, 18, 89)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 280, 490)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1136)
[M::mem_pestat] mean and std.dev: (303.04, 199.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1459)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 227, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 676)
[M::mem_pestat] mean and std.dev: (250.91, 123.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 850)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (471, 562, 1080)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2298)
[M::mem_pestat] mean and std.dev: (630.12, 442.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2907)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 265, 388)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 798)
[M::mem_pestat] mean and std.dev: (258.85, 118.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1003)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701346 sequences (100000002 bp) in 2.253 CPU sec, 2.361 real sec...
[M::process] read 702414 sequences (100000135 bp) in 1.460 CPU sec, 1.458 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 287336, 20, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 351, 588)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1404)
[M::mem_pestat] mean and std.dev: (375.08, 306.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1812)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 228, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 674)
[M::mem_pestat] mean and std.dev: (251.00, 122.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 847)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 447, 626)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1554)
[M::mem_pestat] mean and std.dev: (381.32, 226.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2018)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 290, 515)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1171)
[M::mem_pestat] mean and std.dev: (352.20, 236.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1499)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702330 reads in 175.632 CPU sec, 5.681 real sec
[M::mem_process_seqs] Processed 701748 reads in 114.635 CPU sec, 3.649 real sec
sorting block 22, #reads = 1084723 mem = 536879683 peak = 953364480
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (92, 287239, 26, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 291, 510)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1156)
[M::mem_pestat] mean and std.dev: (311.65, 209.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1479)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 230, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 684)
[M::mem_pestat] mean and std.dev: (253.44, 124.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 860)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (339, 752, 956)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2190)
[M::mem_pestat] mean and std.dev: (635.00, 412.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2807)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 304, 447)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1007)
[M::mem_pestat] mean and std.dev: (294.73, 188.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1287)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706228 sequences (100000099 bp) in 2.488 CPU sec, 2.605 real sec...
[M::process] read 705454 sequences (100000057 bp) in 1.796 CPU sec, 1.795 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 287301, 24, 75)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (228, 344, 523)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1113)
[M::mem_pestat] mean and std.dev: (379.02, 244.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1408)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 227, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 679)
[M::mem_pestat] mean and std.dev: (251.17, 123.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 854)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (356, 1227, 3481)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9731)
[M::mem_pestat] mean and std.dev: (2466.33, 3023.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14559)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 287, 571)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1353)
[M::mem_pestat] mean and std.dev: (367.68, 282.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1744)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701346 reads in 178.447 CPU sec, 5.700 real sec
[M::mem_process_seqs] Processed 702414 reads in 117.250 CPU sec, 3.797 real sec
sorting block 23, #reads = 1082841 mem = 536877371 peak = 953364480
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 288221, 13, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 287, 732)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1894)
[M::mem_pestat] mean and std.dev: (353.05, 304.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2475)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 218, 316)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 650)
[M::mem_pestat] mean and std.dev: (241.63, 118.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 817)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (428, 770, 1614)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3986)
[M::mem_pestat] mean and std.dev: (723.25, 480.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5172)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 291, 643)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1545)
[M::mem_pestat] mean and std.dev: (378.27, 318.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1996)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704514 sequences (100000046 bp) in 2.524 CPU sec, 2.621 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 288631, 22, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 258, 946)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2494)
[M::mem_pestat] mean and std.dev: (561.74, 654.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3268)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 221, 319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 657)
[M::mem_pestat] mean and std.dev: (244.24, 119.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 826)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 432, 1020)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2654)
[M::mem_pestat] mean and std.dev: (580.95, 614.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3471)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 292, 456)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 972)
[M::mem_pestat] mean and std.dev: (317.37, 150.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1230)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703840 sequences (100000297 bp) in 1.899 CPU sec, 1.905 real sec...
[M::mem_process_seqs] Processed 706228 reads in 177.599 CPU sec, 5.713 real sec
sorting block 24, #reads = 1084317 mem = 536876324 peak = 953364480
[M::mem_process_seqs] Processed 705454 reads in 114.133 CPU sec, 3.610 real sec
sorting block 25, #reads = 1086668 mem = 536877506 peak = 953364480
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 288380, 29, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 327, 552)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1266)
[M::mem_pestat] mean and std.dev: (377.07, 262.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1623)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 223, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 662)
[M::mem_pestat] mean and std.dev: (246.22, 120.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 832)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (389, 561, 693)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1301)
[M::mem_pestat] mean and std.dev: (491.36, 282.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1622)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 293, 447)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 929)
[M::mem_pestat] mean and std.dev: (295.71, 161.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1170)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703342 sequences (100000029 bp) in 2.558 CPU sec, 2.671 real sec...
[M::process] read 702990 sequences (100000228 bp) in 1.870 CPU sec, 1.873 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 288521, 13, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (131, 184, 315)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 683)
[M::mem_pestat] mean and std.dev: (219.55, 110.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 867)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 225, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 668)
[M::mem_pestat] mean and std.dev: (248.25, 121.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 840)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (65, 177, 454)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1232)
[M::mem_pestat] mean and std.dev: (252.17, 286.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1621)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (232, 309, 517)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1087)
[M::mem_pestat] mean and std.dev: (323.04, 162.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1372)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704514 reads in 179.461 CPU sec, 5.790 real sec
[M::mem_process_seqs] Processed 703840 reads in 116.209 CPU sec, 3.776 real sec
sorting block 26, #reads = 1085011 mem = 536880341 peak = 953364480
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 287508, 30, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 327, 555)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1265)
[M::mem_pestat] mean and std.dev: (393.79, 249.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1620)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 226, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 672)
[M::mem_pestat] mean and std.dev: (249.25, 122.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 845)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (409, 1226, 2279)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6019)
[M::mem_pestat] mean and std.dev: (1649.46, 1732.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8578)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 303, 465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1061)
[M::mem_pestat] mean and std.dev: (343.59, 224.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1359)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702988 sequences (100000250 bp) in 2.551 CPU sec, 2.668 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 287848, 13, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (138, 262, 1047)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2865)
[M::mem_pestat] mean and std.dev: (451.80, 630.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3774)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 227, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 678)
[M::mem_pestat] mean and std.dev: (250.46, 123.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 853)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 200, 676)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1672)
[M::mem_pestat] mean and std.dev: (410.54, 402.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2170)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 303, 709)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1727)
[M::mem_pestat] mean and std.dev: (399.97, 362.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2236)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702542 sequences (100000220 bp) in 1.850 CPU sec, 1.856 real sec...
[M::mem_process_seqs] Processed 703342 reads in 176.109 CPU sec, 5.685 real sec
[M::mem_process_seqs] Processed 702990 reads in 114.063 CPU sec, 3.716 real sec
sorting block 27, #reads = 1085141 mem = 536878344 peak = 953364480
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 287834, 28, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 251, 403)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 841)
[M::mem_pestat] mean and std.dev: (274.56, 163.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1060)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 227, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 679)
[M::mem_pestat] mean and std.dev: (251.04, 124.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 854)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (123, 394, 1003)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2763)
[M::mem_pestat] mean and std.dev: (651.56, 656.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3643)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 285, 401)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 819)
[M::mem_pestat] mean and std.dev: (285.43, 126.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1028)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702676 sequences (100000091 bp) in 2.274 CPU sec, 2.393 real sec...
[M::process] read 703044 sequences (100000161 bp) in 1.640 CPU sec, 1.632 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 287799, 36, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 462, 1630)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4450)
[M::mem_pestat] mean and std.dev: (821.05, 733.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5860)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 227, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 679)
[M::mem_pestat] mean and std.dev: (251.63, 124.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 854)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (372, 582, 1997)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5247)
[M::mem_pestat] mean and std.dev: (827.60, 779.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6872)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 298, 691)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1639)
[M::mem_pestat] mean and std.dev: (313.22, 222.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2113)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702988 reads in 174.349 CPU sec, 5.656 real sec
sorting block 28, #reads = 1085497 mem = 536880089 peak = 953364480
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 287818, 20, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 285, 416)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 862)
[M::mem_pestat] mean and std.dev: (313.75, 182.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1085)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 226, 327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 673)
[M::mem_pestat] mean and std.dev: (250.43, 123.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 846)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (49, 509, 2179)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6439)
[M::mem_pestat] mean and std.dev: (804.80, 855.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8569)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 281, 414)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 832)
[M::mem_pestat] mean and std.dev: (278.00, 130.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1041)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702940 sequences (100000076 bp) in 1.966 CPU sec, 1.972 real sec...
[M::mem_process_seqs] Processed 702676 reads in 98.408 CPU sec, 3.215 real sec
sorting block 29, #reads = 1083754 mem = 536876547 peak = 953364480
[M::mem_process_seqs] Processed 702542 reads in 239.666 CPU sec, 7.731 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 287507, 17, 85)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 231, 373)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 811)
[M::mem_pestat] mean and std.dev: (255.33, 142.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1030)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 225, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 669)
[M::mem_pestat] mean and std.dev: (248.95, 122.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 841)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (281, 515, 1629)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4325)
[M::mem_pestat] mean and std.dev: (779.62, 694.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5673)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 332, 572)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1326)
[M::mem_pestat] mean and std.dev: (336.17, 219.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1703)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702598 sequences (100000297 bp) in 2.385 CPU sec, 2.672 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 287766, 25, 90)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 301, 866)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2224)
[M::mem_pestat] mean and std.dev: (514.11, 475.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2903)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 225, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 664)
[M::mem_pestat] mean and std.dev: (248.36, 121.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 834)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (126, 733, 1344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3780)
[M::mem_pestat] mean and std.dev: (743.78, 753.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4998)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 329, 875)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2213)
[M::mem_pestat] mean and std.dev: (384.96, 312.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2882)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702474 sequences (100000019 bp) in 1.470 CPU sec, 1.467 real sec...
[M::mem_process_seqs] Processed 703044 reads in 193.308 CPU sec, 6.153 real sec
sorting block 30, #reads = 1084157 mem = 536883401 peak = 953364480
[M::mem_process_seqs] Processed 702940 reads in 114.334 CPU sec, 3.724 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 287899, 31, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 240, 598)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1406)
[M::mem_pestat] mean and std.dev: (330.13, 264.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1810)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 225, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 667)
[M::mem_pestat] mean and std.dev: (248.70, 121.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 838)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (142, 394, 1176)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3244)
[M::mem_pestat] mean and std.dev: (775.53, 906.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4403)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 256, 1107)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2889)
[M::mem_pestat] mean and std.dev: (431.50, 378.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3780)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 31, #reads = 1083739 mem = 536879139 peak = 953364480
[M::process] read 702382 sequences (100000037 bp) in 2.710 CPU sec, 2.863 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (80, 287506, 21, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 290, 676)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1668)
[M::mem_pestat] mean and std.dev: (380.41, 315.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2164)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 226, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 670)
[M::mem_pestat] mean and std.dev: (249.71, 122.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 842)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (326, 583, 1157)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2819)
[M::mem_pestat] mean and std.dev: (698.40, 588.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3650)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 310, 452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 910)
[M::mem_pestat] mean and std.dev: (325.17, 177.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1139)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702358 sequences (100000222 bp) in 1.860 CPU sec, 1.859 real sec...
[M::mem_process_seqs] Processed 702598 reads in 175.927 CPU sec, 5.687 real sec
[M::mem_process_seqs] Processed 702474 reads in 112.039 CPU sec, 3.610 real sec
sorting block 32, #reads = 1082872 mem = 536880517 peak = 953364480
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 287956, 10, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 236, 1222)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3368)
[M::mem_pestat] mean and std.dev: (449.91, 594.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4441)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 227, 327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 673)
[M::mem_pestat] mean and std.dev: (250.26, 122.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 846)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (144, 372, 1108)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3036)
[M::mem_pestat] mean and std.dev: (509.44, 437.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4000)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (234, 285, 605)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1347)
[M::mem_pestat] mean and std.dev: (410.75, 324.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1718)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701976 sequences (100000294 bp) in 2.230 CPU sec, 2.330 real sec...
[M::process] read 701538 sequences (100000121 bp) in 1.840 CPU sec, 1.838 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 287784, 19, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 225, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 785)
[M::mem_pestat] mean and std.dev: (241.71, 140.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 995)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 227, 327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 673)
[M::mem_pestat] mean and std.dev: (250.60, 123.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 846)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (126, 342, 1102)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3054)
[M::mem_pestat] mean and std.dev: (724.58, 763.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4030)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 295, 411)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 849)
[M::mem_pestat] mean and std.dev: (267.78, 112.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1068)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702382 reads in 167.432 CPU sec, 5.362 real sec
[M::mem_process_seqs] Processed 702358 reads in 106.580 CPU sec, 3.380 real sec
sorting block 33, #reads = 1084509 mem = 536879230 peak = 953364480
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 287503, 30, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 260, 452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1028)
[M::mem_pestat] mean and std.dev: (279.02, 191.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1316)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 227, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 674)
[M::mem_pestat] mean and std.dev: (251.14, 123.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 847)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (369, 851, 1205)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2877)
[M::mem_pestat] mean and std.dev: (778.88, 548.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3713)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 371, 570)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1222)
[M::mem_pestat] mean and std.dev: (336.84, 169.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1548)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700984 sequences (100000199 bp) in 2.388 CPU sec, 2.507 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 287642, 26, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 256, 1261)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3445)
[M::mem_pestat] mean and std.dev: (598.56, 742.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4537)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::process] read 702606 sequences (100000112 bp) in 1.730 CPU sec, 1.726 real sec...
[M::mem_pestat] (25, 50, 75) percentile: (156, 229, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 684)
[M::mem_pestat] mean and std.dev: (253.42, 125.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 860)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (137, 621, 2133)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6125)
[M::mem_pestat] mean and std.dev: (1059.92, 1136.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8121)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 257, 441)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1021)
[M::mem_pestat] mean and std.dev: (282.79, 190.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1311)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701976 reads in 167.808 CPU sec, 5.419 real sec
[M::mem_process_seqs] Processed 701538 reads in 108.929 CPU sec, 3.544 real sec
sorting block 34, #reads = 1084588 mem = 536879763 peak = 953364480
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 287471, 23, 80)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 340, 463)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 993)
[M::mem_pestat] mean and std.dev: (328.23, 190.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1258)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 231, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 687)
[M::mem_pestat] mean and std.dev: (254.50, 125.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 864)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (343, 408, 1336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3322)
[M::mem_pestat] mean and std.dev: (554.42, 455.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4315)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 312, 602)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1416)
[M::mem_pestat] mean and std.dev: (341.30, 234.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1823)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706600 sequences (100000010 bp) in 2.261 CPU sec, 2.370 real sec...
[M::process] read 705512 sequences (100000012 bp) in 1.370 CPU sec, 1.367 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 287636, 29, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 216, 319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 651)
[M::mem_pestat] mean and std.dev: (247.75, 129.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 817)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 227, 327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 673)
[M::mem_pestat] mean and std.dev: (250.40, 122.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 846)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (292, 683, 1078)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2650)
[M::mem_pestat] mean and std.dev: (695.50, 448.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3436)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 281, 474)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 972)
[M::mem_pestat] mean and std.dev: (301.82, 141.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1221)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700984 reads in 168.199 CPU sec, 5.440 real sec
sorting block 35, #reads = 1084730 mem = 536878181 peak = 953364480
[M::mem_process_seqs] Processed 702606 reads in 107.415 CPU sec, 3.421 real sec
sorting block 36, #reads = 1082971 mem = 536878398 peak = 967819264
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 288899, 16, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (145, 228, 570)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1420)
[M::mem_pestat] mean and std.dev: (383.91, 301.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1845)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 217, 315)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 647)
[M::mem_pestat] mean and std.dev: (241.27, 119.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 813)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 311, 1127)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3009)
[M::mem_pestat] mean and std.dev: (701.81, 902.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4312)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 404, 630)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1502)
[M::mem_pestat] mean and std.dev: (405.02, 274.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1938)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705632 sequences (100000123 bp) in 2.206 CPU sec, 2.299 real sec...
[M::process] read 705026 sequences (100000088 bp) in 1.340 CPU sec, 1.343 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 288698, 20, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 336, 643)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1587)
[M::mem_pestat] mean and std.dev: (427.39, 337.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2059)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 219, 319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 657)
[M::mem_pestat] mean and std.dev: (244.12, 120.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 826)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (270, 990, 3288)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9324)
[M::mem_pestat] mean and std.dev: (2106.90, 2328.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12342)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 335, 692)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1680)
[M::mem_pestat] mean and std.dev: (351.31, 286.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2174)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 706600 reads in 165.370 CPU sec, 5.366 real sec
[M::mem_process_seqs] Processed 705512 reads in 105.443 CPU sec, 3.440 real sec
sorting block 37, #reads = 1085934 mem = 536880081 peak = 967819264
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 288326, 31, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 339, 1043)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2743)
[M::mem_pestat] mean and std.dev: (603.31, 587.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3593)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 221, 320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 660)
[M::mem_pestat] mean and std.dev: (244.97, 121.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 830)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (117, 506, 1657)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4737)
[M::mem_pestat] mean and std.dev: (1004.03, 1204.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6277)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 279, 798)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2086)
[M::mem_pestat] mean and std.dev: (433.53, 343.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2730)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704470 sequences (100000109 bp) in 2.220 CPU sec, 2.326 real sec...
[M::process] read 704594 sequences (100000245 bp) in 1.710 CPU sec, 1.705 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 288406, 8, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 299, 750)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1948)
[M::mem_pestat] mean and std.dev: (426.02, 314.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2547)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 221, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 664)
[M::mem_pestat] mean and std.dev: (246.34, 122.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 835)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 237, 625)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1605)
[M::mem_pestat] mean and std.dev: (292.82, 245.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2095)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 705632 reads in 172.460 CPU sec, 5.561 real sec
[M::mem_process_seqs] Processed 705026 reads in 110.784 CPU sec, 3.518 real sec
sorting block 38, #reads = 1087070 mem = 536882393 peak = 967819264
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 288553, 21, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 285, 812)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2056)
[M::mem_pestat] mean and std.dev: (480.09, 430.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2678)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 223, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 668)
[M::mem_pestat] mean and std.dev: (248.08, 123.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 840)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (701, 1878, 2098)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4892)
[M::mem_pestat] mean and std.dev: (1457.48, 867.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6289)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 268, 518)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1188)
[M::mem_pestat] mean and std.dev: (305.98, 163.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1523)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703986 sequences (100000003 bp) in 2.211 CPU sec, 2.326 real sec...
[M::process] read 703492 sequences (100000193 bp) in 1.490 CPU sec, 1.494 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 288024, 28, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 316, 1148)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3036)
[M::mem_pestat] mean and std.dev: (630.28, 650.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3980)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 223, 323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 667)
[M::mem_pestat] mean and std.dev: (247.16, 122.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 839)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (439, 778, 1188)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2686)
[M::mem_pestat] mean and std.dev: (670.12, 433.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3435)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 264, 393)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 765)
[M::mem_pestat] mean and std.dev: (286.02, 136.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 951)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704470 reads in 177.499 CPU sec, 5.680 real sec
sorting block 39, #reads = 1086259 mem = 536879114 peak = 967819264
[M::mem_process_seqs] Processed 704594 reads in 112.889 CPU sec, 3.596 real sec
sorting block 40, #reads = 1085383 mem = 536879123 peak = 967819264
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 288457, 15, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 207, 555)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1361)
[M::mem_pestat] mean and std.dev: (270.74, 213.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1764)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 224, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 674)
[M::mem_pestat] mean and std.dev: (248.72, 123.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 848)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (683, 778, 842)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (365, 1160)
[M::mem_pestat] mean and std.dev: (734.85, 115.51)
[M::mem_pestat] low and high boundaries for proper pairs: (206, 1319)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 249, 452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 962)
[M::mem_pestat] mean and std.dev: (248.12, 108.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1217)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703068 sequences (100000066 bp) in 2.173 CPU sec, 2.264 real sec...
[M::process] read 702958 sequences (100000294 bp) in 1.490 CPU sec, 1.492 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 287745, 29, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 251, 633)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1605)
[M::mem_pestat] mean and std.dev: (417.42, 361.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2091)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 225, 327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 675)
[M::mem_pestat] mean and std.dev: (250.22, 124.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 849)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (102, 438, 1644)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4728)
[M::mem_pestat] mean and std.dev: (1016.75, 1095.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6270)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 300, 383)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 793)
[M::mem_pestat] mean and std.dev: (278.78, 136.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 998)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703986 reads in 173.324 CPU sec, 5.587 real sec
[M::mem_process_seqs] Processed 703492 reads in 113.202 CPU sec, 3.601 real sec
sorting block 41, #reads = 1085779 mem = 536883160 peak = 967819264
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 287386, 25, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 300, 1246)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3352)
[M::mem_pestat] mean and std.dev: (740.57, 970.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4623)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 225, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 670)
[M::mem_pestat] mean and std.dev: (249.93, 123.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 842)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (608, 900, 1555)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3449)
[M::mem_pestat] mean and std.dev: (1006.83, 744.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4396)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 303, 446)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 912)
[M::mem_pestat] mean and std.dev: (303.91, 175.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1145)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703160 sequences (100000197 bp) in 2.527 CPU sec, 2.632 real sec...
[M::process] read 703270 sequences (100000122 bp) in 1.430 CPU sec, 1.428 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 287541, 27, 76)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 218, 421)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 941)
[M::mem_pestat] mean and std.dev: (272.88, 183.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1201)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 226, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 672)
[M::mem_pestat] mean and std.dev: (249.51, 122.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 845)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (277, 684, 1160)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2926)
[M::mem_pestat] mean and std.dev: (706.00, 586.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3809)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 283, 418)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 894)
[M::mem_pestat] mean and std.dev: (294.63, 162.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1132)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703068 reads in 169.977 CPU sec, 5.500 real sec
[M::mem_process_seqs] Processed 702958 reads in 110.155 CPU sec, 3.515 real sec
sorting block 42, #reads = 1084841 mem = 536882241 peak = 967819264
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 287776, 22, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 256, 412)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 894)
[M::mem_pestat] mean and std.dev: (292.61, 209.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1135)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 225, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 669)
[M::mem_pestat] mean and std.dev: (248.72, 122.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 841)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (529, 818, 3892)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10618)
[M::mem_pestat] mean and std.dev: (1905.50, 2047.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13981)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 286, 531)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1157)
[M::mem_pestat] mean and std.dev: (328.40, 201.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1470)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702506 sequences (100000226 bp) in 2.630 CPU sec, 2.720 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 287548, 22, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (144, 204, 405)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 927)
[M::mem_pestat] mean and std.dev: (233.06, 134.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1188)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 223, 323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 663)
[M::mem_pestat] mean and std.dev: (247.52, 121.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 833)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (694, 1014, 2498)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6106)
[M::mem_pestat] mean and std.dev: (1353.68, 1353.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7910)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 317, 432)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 912)
[M::mem_pestat] mean and std.dev: (275.20, 136.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1152)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702592 sequences (100000003 bp) in 1.888 CPU sec, 1.897 real sec...
[M::mem_process_seqs] Processed 703160 reads in 173.382 CPU sec, 5.512 real sec
sorting block 43, #reads = 1083099 mem = 536878307 peak = 967819264
[M::mem_process_seqs] Processed 703270 reads in 117.332 CPU sec, 3.736 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 287749, 17, 82)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (249, 418, 653)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1461)
[M::mem_pestat] mean and std.dev: (439.32, 290.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1865)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 226, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 667)
[M::mem_pestat] mean and std.dev: (249.38, 122.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 838)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (485, 736, 2567)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6731)
[M::mem_pestat] mean and std.dev: (1408.88, 1547.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8813)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 261, 403)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 833)
[M::mem_pestat] mean and std.dev: (274.23, 132.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1048)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 44, #reads = 1084354 mem = 536879623 peak = 967819264
[M::process] read 702120 sequences (100000028 bp) in 2.744 CPU sec, 2.866 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 287690, 21, 77)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 234, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 690)
[M::mem_pestat] mean and std.dev: (245.91, 119.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 867)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 226, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 667)
[M::mem_pestat] mean and std.dev: (248.98, 121.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 838)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (542, 1051, 5625)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 15791)
[M::mem_pestat] mean and std.dev: (2708.48, 3032.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 20874)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 356, 770)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1968)
[M::mem_pestat] mean and std.dev: (397.33, 353.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2567)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701730 sequences (100000256 bp) in 1.856 CPU sec, 1.858 real sec...
[M::mem_process_seqs] Processed 702506 reads in 180.650 CPU sec, 5.765 real sec
[M::mem_process_seqs] Processed 702592 reads in 119.991 CPU sec, 3.801 real sec
sorting block 45, #reads = 1082869 mem = 536877106 peak = 967819264
[M::process] read 701476 sequences (100000051 bp) in 2.720 CPU sec, 2.829 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 287228, 23, 73)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 240, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 674)
[M::mem_pestat] mean and std.dev: (244.85, 119.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 845)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 228, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 674)
[M::mem_pestat] mean and std.dev: (250.98, 122.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 847)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (676, 880, 1063)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1837)
[M::mem_pestat] mean and std.dev: (789.55, 431.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2515)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 319, 426)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 836)
[M::mem_pestat] mean and std.dev: (318.71, 153.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1041)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701030 sequences (100000149 bp) in 1.872 CPU sec, 1.881 real sec...
[M::mem_process_seqs] Processed 701730 reads in 103.805 CPU sec, 3.278 real sec
sorting block 46, #reads = 1083844 mem = 536882297 peak = 967819264
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 287648, 24, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 244, 439)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 983)
[M::mem_pestat] mean and std.dev: (295.86, 188.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1255)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 227, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 674)
[M::mem_pestat] mean and std.dev: (250.64, 122.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 847)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 380, 1176)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3196)
[M::mem_pestat] mean and std.dev: (605.68, 726.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4206)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 250, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 672)
[M::mem_pestat] mean and std.dev: (253.27, 119.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 842)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 286664, 26, 74)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 230, 457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1041)
[M::mem_pestat] mean and std.dev: (307.38, 222.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1333)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 229, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 680)
[M::mem_pestat] mean and std.dev: (252.30, 123.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 855)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (365, 539, 1676)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4298)
[M::mem_pestat] mean and std.dev: (1158.58, 1059.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5609)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 264, 457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 979)
[M::mem_pestat] mean and std.dev: (305.86, 153.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1240)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705216 sequences (100000002 bp) in 1.991 CPU sec, 1.993 real sec...
[M::mem_process_seqs] Processed 702120 reads in 278.468 CPU sec, 8.930 real sec
[M::mem_process_seqs] Processed 701476 reads in 140.053 CPU sec, 4.549 real sec
sorting block 47, #reads = 1083292 mem = 536883020 peak = 967819264
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 287390, 21, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 277, 625)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1537)
[M::mem_pestat] mean and std.dev: (304.73, 233.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1993)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 231, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 687)
[M::mem_pestat] mean and std.dev: (254.17, 124.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 864)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (250, 423, 685)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1555)
[M::mem_pestat] mean and std.dev: (385.15, 225.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1990)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 394, 663)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1593)
[M::mem_pestat] mean and std.dev: (476.33, 350.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2058)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 710240 sequences (100000175 bp) in 2.369 CPU sec, 2.491 real sec...
[M::process] read 708814 sequences (100000048 bp) in 1.763 CPU sec, 1.770 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 288805, 30, 75)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 292, 549)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1293)
[M::mem_pestat] mean and std.dev: (276.26, 142.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1665)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 221, 320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 658)
[M::mem_pestat] mean and std.dev: (245.18, 121.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 827)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (293, 639, 1023)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2483)
[M::mem_pestat] mean and std.dev: (624.11, 350.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3213)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 281, 505)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1095)
[M::mem_pestat] mean and std.dev: (317.16, 192.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1390)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701030 reads in 183.354 CPU sec, 5.931 real sec
[M::mem_process_seqs] Processed 705216 reads in 122.362 CPU sec, 3.893 real sec
sorting block 48, #reads = 1083262 mem = 536882140 peak = 967819264
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 290549, 18, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 266, 594)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1434)
[M::mem_pestat] mean and std.dev: (389.02, 284.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1854)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (144, 207, 300)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 612)
[M::mem_pestat] mean and std.dev: (231.31, 113.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 768)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (119, 382, 2349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6809)
[M::mem_pestat] mean and std.dev: (905.65, 1025.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9039)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 266, 355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 685)
[M::mem_pestat] mean and std.dev: (264.75, 120.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 850)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 707992 sequences (100000231 bp) in 2.225 CPU sec, 2.340 real sec...
[M::process] read 707172 sequences (100000000 bp) in 1.816 CPU sec, 1.853 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 290179, 16, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 256, 457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 973)
[M::mem_pestat] mean and std.dev: (300.81, 149.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1231)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 211, 307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 629)
[M::mem_pestat] mean and std.dev: (236.02, 117.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 790)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (472, 1245, 1609)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3883)
[M::mem_pestat] mean and std.dev: (1079.40, 858.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5020)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 250, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 746)
[M::mem_pestat] mean and std.dev: (243.50, 102.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 937)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 710240 reads in 180.262 CPU sec, 5.747 real sec
[M::mem_process_seqs] Processed 708814 reads in 119.617 CPU sec, 3.822 real sec
sorting block 49, #reads = 1085419 mem = 536880936 peak = 967819264
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 289919, 27, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 238, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 664)
[M::mem_pestat] mean and std.dev: (225.87, 68.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 826)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 214, 311)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 639)
[M::mem_pestat] mean and std.dev: (238.67, 118.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 803)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (117, 332, 1918)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5520)
[M::mem_pestat] mean and std.dev: (1235.15, 1669.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7913)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 264, 1442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3902)
[M::mem_pestat] mean and std.dev: (688.75, 817.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5132)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706448 sequences (100000026 bp) in 2.702 CPU sec, 2.908 real sec...
[M::process] read 705896 sequences (100000233 bp) in 1.837 CPU sec, 1.844 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 290185, 30, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (141, 233, 638)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1632)
[M::mem_pestat] mean and std.dev: (356.13, 302.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2129)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 215, 314)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 646)
[M::mem_pestat] mean and std.dev: (240.81, 120.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 812)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (142, 420, 965)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2611)
[M::mem_pestat] mean and std.dev: (604.11, 551.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3434)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 294, 673)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1579)
[M::mem_pestat] mean and std.dev: (391.76, 304.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2032)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 707992 reads in 192.816 CPU sec, 6.425 real sec
sorting block 50, #reads = 1087402 mem = 536880098 peak = 967819264
[M::mem_process_seqs] Processed 707172 reads in 128.347 CPU sec, 4.112 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 289446, 26, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 217, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 634)
[M::mem_pestat] mean and std.dev: (223.21, 105.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 788)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 217, 317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 653)
[M::mem_pestat] mean and std.dev: (243.09, 121.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 821)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 693, 1037)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2697)
[M::mem_pestat] mean and std.dev: (745.96, 553.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3527)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 246, 548)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1252)
[M::mem_pestat] mean and std.dev: (335.28, 235.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1604)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 51, #reads = 1086001 mem = 536889423 peak = 1006338048
[M::process] read 705544 sequences (100000296 bp) in 2.507 CPU sec, 2.786 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 289083, 18, 75)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 286, 462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1044)
[M::mem_pestat] mean and std.dev: (276.64, 147.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1335)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 219, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 665)
[M::mem_pestat] mean and std.dev: (245.32, 123.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 837)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (117, 422, 1327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3747)
[M::mem_pestat] mean and std.dev: (495.60, 611.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4957)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 309, 567)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1361)
[M::mem_pestat] mean and std.dev: (307.47, 176.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1758)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704496 sequences (100000219 bp) in 1.900 CPU sec, 1.902 real sec...
[M::mem_process_seqs] Processed 706448 reads in 184.619 CPU sec, 6.051 real sec
[M::mem_process_seqs] Processed 705896 reads in 122.818 CPU sec, 3.934 real sec
sorting block 52, #reads = 1086279 mem = 536880488 peak = 1006338048
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 288498, 22, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (233, 327, 521)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1097)
[M::mem_pestat] mean and std.dev: (355.98, 195.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1385)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 219, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 663)
[M::mem_pestat] mean and std.dev: (245.42, 123.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 834)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (276, 811, 2052)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5604)
[M::mem_pestat] mean and std.dev: (1242.18, 1268.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7380)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 295, 946)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2492)
[M::mem_pestat] mean and std.dev: (551.64, 512.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3265)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704182 sequences (100000144 bp) in 2.555 CPU sec, 2.725 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (74, 288455, 22, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (236, 331, 599)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1325)
[M::mem_pestat] mean and std.dev: (364.43, 200.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1688)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 221, 323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 667)
[M::mem_pestat] mean and std.dev: (247.53, 124.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 839)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (414, 879, 1587)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3933)
[M::mem_pestat] mean and std.dev: (848.47, 749.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5106)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 255, 481)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1151)
[M::mem_pestat] mean and std.dev: (287.80, 198.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1486)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703934 sequences (100000167 bp) in 1.838 CPU sec, 1.867 real sec...
[M::mem_process_seqs] Processed 705544 reads in 191.525 CPU sec, 6.183 real sec
[M::mem_process_seqs] Processed 704496 reads in 124.539 CPU sec, 3.991 real sec
sorting block 53, #reads = 1085259 mem = 536878276 peak = 1006338048
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 288232, 32, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 243, 444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 994)
[M::mem_pestat] mean and std.dev: (284.86, 179.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1269)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 222, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 668)
[M::mem_pestat] mean and std.dev: (247.96, 123.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 840)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (508, 641, 1475)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3409)
[M::mem_pestat] mean and std.dev: (682.56, 455.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4376)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 329, 770)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1872)
[M::mem_pestat] mean and std.dev: (491.26, 467.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2423)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703986 sequences (100000001 bp) in 2.590 CPU sec, 2.815 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (74, 287996, 34, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 243, 292)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 566)
[M::mem_pestat] mean and std.dev: (215.10, 86.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 703)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 223, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 671)
[M::mem_pestat] mean and std.dev: (248.32, 123.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 844)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (301, 514, 1081)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2641)
[M::mem_pestat] mean and std.dev: (689.76, 472.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3421)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 264, 415)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 853)
[M::mem_pestat] mean and std.dev: (296.02, 176.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1072)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703804 sequences (100000070 bp) in 1.851 CPU sec, 1.857 real sec...
[M::mem_process_seqs] Processed 704182 reads in 190.566 CPU sec, 6.119 real sec
sorting block 54, #reads = 1083836 mem = 536879462 peak = 1006338048
[M::mem_process_seqs] Processed 703934 reads in 125.983 CPU sec, 4.028 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 288511, 17, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 234, 537)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1303)
[M::mem_pestat] mean and std.dev: (332.01, 273.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1686)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 223, 323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 665)
[M::mem_pestat] mean and std.dev: (247.78, 123.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 836)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (511, 557, 941)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1801)
[M::mem_pestat] mean and std.dev: (598.56, 333.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2231)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 335, 602)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1406)
[M::mem_pestat] mean and std.dev: (401.81, 308.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1808)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 55, #reads = 1083116 mem = 536881281 peak = 1052041216
[M::process] read 703062 sequences (100000086 bp) in 2.646 CPU sec, 2.823 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 288245, 18, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 267, 572)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1382)
[M::mem_pestat] mean and std.dev: (273.31, 154.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1787)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 222, 323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 665)
[M::mem_pestat] mean and std.dev: (247.31, 122.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 836)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (314, 737, 1316)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3320)
[M::mem_pestat] mean and std.dev: (694.39, 497.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4322)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 244, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 686)
[M::mem_pestat] mean and std.dev: (247.62, 112.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 859)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703228 sequences (100000217 bp) in 1.783 CPU sec, 1.810 real sec...
[M::mem_process_seqs] Processed 703986 reads in 187.030 CPU sec, 6.001 real sec
[M::mem_process_seqs] Processed 703804 reads in 125.810 CPU sec, 4.262 real sec
sorting block 56, #reads = 1082970 mem = 536879569 peak = 1052041216
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 287989, 19, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 258, 410)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 832)
[M::mem_pestat] mean and std.dev: (276.32, 144.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1043)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 225, 327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 675)
[M::mem_pestat] mean and std.dev: (249.84, 123.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 849)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (264, 999, 1847)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5013)
[M::mem_pestat] mean and std.dev: (799.73, 593.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6596)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 268, 455)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1053)
[M::mem_pestat] mean and std.dev: (285.98, 185.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1352)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702948 sequences (100000270 bp) in 2.790 CPU sec, 2.988 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 287786, 33, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (122, 228, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 761)
[M::mem_pestat] mean and std.dev: (224.31, 115.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 974)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 224, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 666)
[M::mem_pestat] mean and std.dev: (248.64, 122.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 837)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (908, 1524, 1878)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3818)
[M::mem_pestat] mean and std.dev: (1369.90, 773.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4788)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 277, 420)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 842)
[M::mem_pestat] mean and std.dev: (255.33, 105.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1053)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703378 sequences (100000037 bp) in 1.940 CPU sec, 1.939 real sec...
[M::mem_process_seqs] Processed 703062 reads in 193.657 CPU sec, 6.433 real sec
[M::mem_process_seqs] Processed 703228 reads in 125.427 CPU sec, 4.009 real sec
sorting block 57, #reads = 1081243 mem = 536878415 peak = 1052041216
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 287955, 24, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 257, 446)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1006)
[M::mem_pestat] mean and std.dev: (271.46, 173.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1286)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 225, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 666)
[M::mem_pestat] mean and std.dev: (248.63, 121.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 837)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (35, 880, 2459)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7307)
[M::mem_pestat] mean and std.dev: (914.00, 1567.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9731)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 223, 390)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 838)
[M::mem_pestat] mean and std.dev: (262.75, 144.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1062)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703126 sequences (100000198 bp) in 2.699 CPU sec, 2.918 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 287936, 23, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 263, 682)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1690)
[M::mem_pestat] mean and std.dev: (406.87, 350.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2194)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 224, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 666)
[M::mem_pestat] mean and std.dev: (248.46, 122.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 837)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 550, 3008)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8602)
[M::mem_pestat] mean and std.dev: (1667.52, 2274.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11399)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 292, 420)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 884)
[M::mem_pestat] mean and std.dev: (289.46, 149.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1116)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 708870 sequences (100000217 bp) in 1.956 CPU sec, 1.961 real sec...
[M::mem_process_seqs] Processed 702948 reads in 189.097 CPU sec, 6.158 real sec
sorting block 58, #reads = 1081393 mem = 536880080 peak = 1052041216
[M::mem_process_seqs] Processed 703378 reads in 126.133 CPU sec, 4.124 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (76, 288299, 23, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 481, 808)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1998)
[M::mem_pestat] mean and std.dev: (529.04, 479.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2593)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 224, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 669)
[M::mem_pestat] mean and std.dev: (248.73, 122.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 841)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (693, 941, 1276)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2442)
[M::mem_pestat] mean and std.dev: (768.16, 443.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3025)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 263, 930)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2426)
[M::mem_pestat] mean and std.dev: (516.05, 511.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3174)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 59, #reads = 1081361 mem = 536881370 peak = 1052041216
[M::process] read 711216 sequences (100000200 bp) in 2.754 CPU sec, 2.926 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 290143, 21, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 317, 830)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2056)
[M::mem_pestat] mean and std.dev: (426.83, 314.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2669)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 212, 307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 629)
[M::mem_pestat] mean and std.dev: (235.96, 116.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 790)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (310, 810, 1095)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2665)
[M::mem_pestat] mean and std.dev: (703.75, 500.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3450)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 301, 560)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1304)
[M::mem_pestat] mean and std.dev: (338.00, 201.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1676)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 709414 sequences (100000288 bp) in 1.901 CPU sec, 1.911 real sec...
[M::mem_process_seqs] Processed 703126 reads in 197.239 CPU sec, 6.494 real sec
[M::mem_process_seqs] Processed 708870 reads in 134.289 CPU sec, 4.300 real sec
sorting block 60, #reads = 1081825 mem = 536887792 peak = 1052041216
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 291344, 27, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 220, 510)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1216)
[M::mem_pestat] mean and std.dev: (307.84, 248.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1569)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (143, 206, 297)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 605)
[M::mem_pestat] mean and std.dev: (229.47, 112.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 759)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (103, 443, 866)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2392)
[M::mem_pestat] mean and std.dev: (513.58, 493.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3155)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 295, 450)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 988)
[M::mem_pestat] mean and std.dev: (324.68, 191.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1257)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 709376 sequences (100000078 bp) in 2.565 CPU sec, 2.648 real sec...
[M::process] read 709394 sequences (100000124 bp) in 1.630 CPU sec, 1.636 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 290874, 13, 70)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (227, 278, 489)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1013)
[M::mem_pestat] mean and std.dev: (293.63, 180.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1275)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 210, 304)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 622)
[M::mem_pestat] mean and std.dev: (234.14, 115.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 781)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (431, 842, 2351)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6191)
[M::mem_pestat] mean and std.dev: (978.46, 786.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8111)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 286, 491)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1089)
[M::mem_pestat] mean and std.dev: (317.67, 176.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1388)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 711216 reads in 186.702 CPU sec, 5.958 real sec
[M::mem_process_seqs] Processed 709414 reads in 122.419 CPU sec, 3.896 real sec
sorting block 61, #reads = 1085187 mem = 536879900 peak = 1052041216
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 289997, 26, 81)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (132, 291, 1098)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3030)
[M::mem_pestat] mean and std.dev: (404.13, 411.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3996)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 211, 306)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 628)
[M::mem_pestat] mean and std.dev: (235.16, 116.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 789)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (646, 1569, 7700)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 21808)
[M::mem_pestat] mean and std.dev: (2781.04, 3124.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 28862)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 295, 691)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1743)
[M::mem_pestat] mean and std.dev: (387.93, 325.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2269)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 707904 sequences (100000130 bp) in 2.455 CPU sec, 2.535 real sec...
[M::process] read 707130 sequences (100000175 bp) in 1.910 CPU sec, 1.917 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 290980, 22, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 219, 930)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2446)
[M::mem_pestat] mean and std.dev: (513.74, 509.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3204)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 210, 305)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 625)
[M::mem_pestat] mean and std.dev: (234.63, 116.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 785)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (337, 589, 711)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1459)
[M::mem_pestat] mean and std.dev: (525.27, 321.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1833)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 322, 504)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1180)
[M::mem_pestat] mean and std.dev: (313.73, 189.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1518)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 709376 reads in 188.763 CPU sec, 6.246 real sec
sorting block 62, #reads = 1085157 mem = 536881858 peak = 1052041216
[M::mem_process_seqs] Processed 709394 reads in 123.266 CPU sec, 4.024 real sec
sorting block 63, #reads = 1084064 mem = 536880342 peak = 1052041216
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 290071, 28, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (135, 291, 2093)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6009)
[M::mem_pestat] mean and std.dev: (1278.33, 1830.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8600)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 213, 311)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 639)
[M::mem_pestat] mean and std.dev: (238.76, 119.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 803)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 600, 1425)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3941)
[M::mem_pestat] mean and std.dev: (626.73, 544.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5199)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 289, 732)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1794)
[M::mem_pestat] mean and std.dev: (475.85, 431.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2325)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 707244 sequences (100000111 bp) in 2.531 CPU sec, 2.597 real sec...
[M::process] read 705996 sequences (100000004 bp) in 1.882 CPU sec, 1.891 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 289866, 13, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (129, 249, 580)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1482)
[M::mem_pestat] mean and std.dev: (314.82, 219.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1933)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 215, 313)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 643)
[M::mem_pestat] mean and std.dev: (240.39, 119.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 808)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (377, 494, 1755)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4511)
[M::mem_pestat] mean and std.dev: (984.08, 805.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5889)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 265, 721)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1799)
[M::mem_pestat] mean and std.dev: (350.53, 320.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2338)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 707904 reads in 182.231 CPU sec, 5.886 real sec
[M::mem_process_seqs] Processed 707130 reads in 115.418 CPU sec, 3.758 real sec
sorting block 64, #reads = 1084927 mem = 536880302 peak = 1052041216
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 289561, 12, 77)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 227, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 636)
[M::mem_pestat] mean and std.dev: (249.71, 107.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 793)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 216, 316)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 652)
[M::mem_pestat] mean and std.dev: (242.17, 121.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 820)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (529, 1052, 1333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2941)
[M::mem_pestat] mean and std.dev: (1054.17, 749.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4050)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 337, 636)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1504)
[M::mem_pestat] mean and std.dev: (383.77, 271.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1938)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705234 sequences (100000215 bp) in 2.674 CPU sec, 2.764 real sec...
[M::process] read 704822 sequences (100000176 bp) in 1.940 CPU sec, 1.944 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 289491, 20, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 288, 507)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1115)
[M::mem_pestat] mean and std.dev: (322.98, 173.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1419)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 218, 319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 659)
[M::mem_pestat] mean and std.dev: (244.34, 122.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 829)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 702, 823)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2149)
[M::mem_pestat] mean and std.dev: (518.41, 413.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2812)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (272, 367, 589)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1223)
[M::mem_pestat] mean and std.dev: (386.40, 183.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1540)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 707244 reads in 183.560 CPU sec, 5.925 real sec
[M::mem_process_seqs] Processed 705996 reads in 125.434 CPU sec, 3.990 real sec
sorting block 65, #reads = 1085592 mem = 536880822 peak = 1052041216
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 288421, 18, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 276, 447)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 995)
[M::mem_pestat] mean and std.dev: (270.59, 132.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1269)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 219, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 663)
[M::mem_pestat] mean and std.dev: (245.76, 123.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 834)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (124, 359, 1458)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4126)
[M::mem_pestat] mean and std.dev: (611.81, 788.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5460)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 320, 489)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1015)
[M::mem_pestat] mean and std.dev: (326.33, 178.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1278)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704314 sequences (100000119 bp) in 2.512 CPU sec, 2.564 real sec...
[M::process] read 704214 sequences (100000217 bp) in 1.930 CPU sec, 1.932 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 288299, 19, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 246, 889)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2323)
[M::mem_pestat] mean and std.dev: (489.75, 532.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3040)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 220, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 661)
[M::mem_pestat] mean and std.dev: (245.70, 122.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 831)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (254, 626, 963)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2381)
[M::mem_pestat] mean and std.dev: (541.89, 364.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3090)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 303, 983)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2579)
[M::mem_pestat] mean and std.dev: (501.45, 559.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3377)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 705234 reads in 179.510 CPU sec, 5.691 real sec
sorting block 66, #reads = 1081988 mem = 536881563 peak = 1052041216
[M::mem_process_seqs] Processed 704822 reads in 127.101 CPU sec, 4.035 real sec
sorting block 67, #reads = 1082599 mem = 536880458 peak = 1052041216
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 288125, 28, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 242, 495)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1151)
[M::mem_pestat] mean and std.dev: (336.78, 264.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1479)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 221, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 661)
[M::mem_pestat] mean and std.dev: (246.24, 122.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 831)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (423, 901, 1868)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4758)
[M::mem_pestat] mean and std.dev: (1076.89, 903.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6203)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 275, 411)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 857)
[M::mem_pestat] mean and std.dev: (277.33, 145.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1080)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704402 sequences (100000164 bp) in 2.521 CPU sec, 2.591 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 287925, 13, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (138, 222, 300)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 624)
[M::mem_pestat] mean and std.dev: (214.82, 102.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 786)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::process] read 704166 sequences (100000044 bp) in 1.930 CPU sec, 1.933 real sec...
[M::mem_pestat] (25, 50, 75) percentile: (152, 221, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 662)
[M::mem_pestat] mean and std.dev: (246.46, 122.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 832)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (228, 378, 987)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2505)
[M::mem_pestat] mean and std.dev: (518.69, 458.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3264)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 381, 848)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2182)
[M::mem_pestat] mean and std.dev: (432.19, 449.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2849)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704314 reads in 176.601 CPU sec, 5.615 real sec
[M::mem_process_seqs] Processed 704214 reads in 124.235 CPU sec, 3.956 real sec
sorting block 68, #reads = 1082011 mem = 536879325 peak = 1052041216
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 288491, 25, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 266, 438)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 984)
[M::mem_pestat] mean and std.dev: (259.65, 138.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1257)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 222, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 670)
[M::mem_pestat] mean and std.dev: (247.39, 123.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 843)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (365, 1023, 1551)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3923)
[M::mem_pestat] mean and std.dev: (1135.21, 997.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5125)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (232, 308, 584)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1288)
[M::mem_pestat] mean and std.dev: (331.22, 202.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1640)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703572 sequences (100000089 bp) in 2.678 CPU sec, 2.773 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 288322, 26, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 298, 704)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1692)
[M::mem_pestat] mean and std.dev: (397.66, 364.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2186)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 222, 323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 665)
[M::mem_pestat] mean and std.dev: (247.46, 123.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 836)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (360, 434, 902)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1986)
[M::mem_pestat] mean and std.dev: (578.04, 308.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2528)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 305, 430)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 896)
[M::mem_pestat] mean and std.dev: (319.64, 184.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1129)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703652 sequences (100000173 bp) in 1.910 CPU sec, 1.908 real sec...
[M::mem_process_seqs] Processed 704402 reads in 175.138 CPU sec, 5.563 real sec
[M::mem_process_seqs] Processed 704166 reads in 116.493 CPU sec, 3.776 real sec
sorting block 69, #reads = 1083281 mem = 536886795 peak = 1052041216
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (74, 287878, 25, 74)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 260, 778)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2024)
[M::mem_pestat] mean and std.dev: (334.48, 293.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2647)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 223, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 674)
[M::mem_pestat] mean and std.dev: (249.61, 125.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 848)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (37, 429, 927)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2707)
[M::mem_pestat] mean and std.dev: (422.32, 446.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3597)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 298, 466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1036)
[M::mem_pestat] mean and std.dev: (302.31, 167.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1321)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 708076 sequences (100000116 bp) in 2.681 CPU sec, 2.741 real sec...
[M::process] read 709362 sequences (100000011 bp) in 1.920 CPU sec, 1.921 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 288352, 21, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 242, 352)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 718)
[M::mem_pestat] mean and std.dev: (252.55, 118.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 901)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 223, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 671)
[M::mem_pestat] mean and std.dev: (248.95, 124.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 844)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 568, 2249)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6433)
[M::mem_pestat] mean and std.dev: (664.22, 717.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8525)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 251, 690)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1726)
[M::mem_pestat] mean and std.dev: (324.93, 263.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2244)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703572 reads in 183.457 CPU sec, 5.940 real sec
sorting block 70, #reads = 1082610 mem = 536879611 peak = 1052041216
[M::mem_process_seqs] Processed 703652 reads in 120.202 CPU sec, 3.933 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 289026, 26, 77)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 261, 518)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1162)
[M::mem_pestat] mean and std.dev: (324.40, 228.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1484)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 213, 308)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 632)
[M::mem_pestat] mean and std.dev: (237.35, 117.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 794)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (110, 392, 1356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3848)
[M::mem_pestat] mean and std.dev: (570.38, 667.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5094)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 285, 573)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1337)
[M::mem_pestat] mean and std.dev: (363.71, 233.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1719)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 707802 sequences (100000226 bp) in 2.459 CPU sec, 2.512 real sec...
[M::process] read 707454 sequences (100000192 bp) in 1.750 CPU sec, 1.750 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 290407, 20, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (134, 228, 416)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 980)
[M::mem_pestat] mean and std.dev: (245.93, 149.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1262)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 211, 305)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 625)
[M::mem_pestat] mean and std.dev: (234.73, 115.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 785)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (299, 823, 1512)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3938)
[M::mem_pestat] mean and std.dev: (860.90, 686.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5151)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 345, 542)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1176)
[M::mem_pestat] mean and std.dev: (332.54, 166.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1493)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 708076 reads in 188.775 CPU sec, 6.099 real sec
sorting block 71, #reads = 1080546 mem = 536879804 peak = 1052041216
[M::mem_process_seqs] Processed 709362 reads in 114.871 CPU sec, 3.745 real sec
sorting block 72, #reads = 1080129 mem = 536881890 peak = 1052041216
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 290022, 17, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 260, 380)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 790)
[M::mem_pestat] mean and std.dev: (271.62, 123.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 995)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 214, 310)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 636)
[M::mem_pestat] mean and std.dev: (238.29, 117.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 799)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (680, 965, 1244)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2372)
[M::mem_pestat] mean and std.dev: (908.24, 356.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2936)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 272, 474)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1074)
[M::mem_pestat] mean and std.dev: (317.61, 201.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1374)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 707012 sequences (100000280 bp) in 2.621 CPU sec, 2.679 real sec...
[M::process] read 706368 sequences (100000076 bp) in 1.790 CPU sec, 1.787 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 290260, 21, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 361, 473)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1005)
[M::mem_pestat] mean and std.dev: (336.07, 175.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1271)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 215, 312)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 642)
[M::mem_pestat] mean and std.dev: (239.36, 118.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 807)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (32, 634, 1731)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5129)
[M::mem_pestat] mean and std.dev: (742.84, 979.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6828)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 339, 694)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1680)
[M::mem_pestat] mean and std.dev: (390.29, 279.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2173)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 707802 reads in 177.058 CPU sec, 5.707 real sec
[M::mem_process_seqs] Processed 707454 reads in 114.736 CPU sec, 3.632 real sec
sorting block 73, #reads = 1087544 mem = 536880956 peak = 1052041216
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 289816, 24, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 214, 385)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 803)
[M::mem_pestat] mean and std.dev: (254.54, 128.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1012)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 216, 313)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 643)
[M::mem_pestat] mean and std.dev: (240.37, 119.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 808)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (343, 504, 568)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1018)
[M::mem_pestat] mean and std.dev: (406.09, 213.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1259)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 332, 558)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1264)
[M::mem_pestat] mean and std.dev: (384.90, 256.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1617)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706502 sequences (100000205 bp) in 2.284 CPU sec, 2.360 real sec...
[M::process] read 706272 sequences (100000220 bp) in 1.710 CPU sec, 1.705 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 289445, 12, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (144, 254, 409)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 939)
[M::mem_pestat] mean and std.dev: (261.95, 156.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1204)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 217, 316)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 650)
[M::mem_pestat] mean and std.dev: (242.14, 120.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 817)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 698, 1621)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4539)
[M::mem_pestat] mean and std.dev: (755.45, 794.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5998)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 298, 636)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1478)
[M::mem_pestat] mean and std.dev: (369.39, 241.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1899)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 707012 reads in 172.470 CPU sec, 5.489 real sec
[M::mem_process_seqs] Processed 706368 reads in 110.230 CPU sec, 3.494 real sec
sorting block 74, #reads = 1086299 mem = 536878563 peak = 1052041216
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 289598, 22, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 226, 552)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1344)
[M::mem_pestat] mean and std.dev: (313.11, 264.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1740)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 217, 317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 653)
[M::mem_pestat] mean and std.dev: (243.20, 121.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 821)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (517, 1063, 1641)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3889)
[M::mem_pestat] mean and std.dev: (1438.00, 1102.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5846)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 251, 435)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 983)
[M::mem_pestat] mean and std.dev: (295.38, 158.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1257)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706342 sequences (100000268 bp) in 2.424 CPU sec, 2.511 real sec...
[M::process] read 705322 sequences (100000171 bp) in 1.580 CPU sec, 1.574 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 289575, 20, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 260, 564)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1320)
[M::mem_pestat] mean and std.dev: (346.58, 220.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1698)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 218, 317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 653)
[M::mem_pestat] mean and std.dev: (243.46, 121.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 821)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (308, 674, 1616)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4232)
[M::mem_pestat] mean and std.dev: (938.70, 921.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5540)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 309, 447)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1033)
[M::mem_pestat] mean and std.dev: (277.24, 130.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1326)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 706502 reads in 184.544 CPU sec, 5.919 real sec
sorting block 75, #reads = 1086273 mem = 536879868 peak = 1052041216
[M::mem_process_seqs] Processed 706272 reads in 118.522 CPU sec, 3.783 real sec
sorting block 76, #reads = 1083398 mem = 536877686 peak = 1052041216
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 290090, 19, 73)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 349, 758)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1884)
[M::mem_pestat] mean and std.dev: (488.32, 388.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2447)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 218, 318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 656)
[M::mem_pestat] mean and std.dev: (244.04, 122.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 825)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (585, 851, 1924)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4602)
[M::mem_pestat] mean and std.dev: (898.06, 636.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5941)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 384, 751)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1901)
[M::mem_pestat] mean and std.dev: (389.34, 319.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2476)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704412 sequences (100000093 bp) in 2.524 CPU sec, 2.591 real sec...
[M::process] read 704364 sequences (100000122 bp) in 1.720 CPU sec, 1.718 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 289025, 21, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 236, 528)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1244)
[M::mem_pestat] mean and std.dev: (309.16, 207.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1602)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 221, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 666)
[M::mem_pestat] mean and std.dev: (246.48, 123.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 838)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (145, 324, 952)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2566)
[M::mem_pestat] mean and std.dev: (430.47, 343.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3373)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 333, 527)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1203)
[M::mem_pestat] mean and std.dev: (341.52, 215.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1541)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 706342 reads in 172.961 CPU sec, 5.511 real sec
[M::mem_process_seqs] Processed 705322 reads in 115.292 CPU sec, 3.784 real sec
sorting block 77, #reads = 1085336 mem = 536879559 peak = 1052041216
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 288239, 15, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 354, 559)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1287)
[M::mem_pestat] mean and std.dev: (360.90, 230.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1651)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 222, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 670)
[M::mem_pestat] mean and std.dev: (248.04, 124.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 843)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 543, 1304)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3588)
[M::mem_pestat] mean and std.dev: (651.50, 568.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4730)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 269, 388)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 772)
[M::mem_pestat] mean and std.dev: (264.24, 133.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 964)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703782 sequences (100000152 bp) in 2.621 CPU sec, 2.684 real sec...
[M::process] read 704300 sequences (100000031 bp) in 1.800 CPU sec, 1.804 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (80, 288555, 22, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 262, 492)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1180)
[M::mem_pestat] mean and std.dev: (288.48, 179.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1524)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 222, 323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 667)
[M::mem_pestat] mean and std.dev: (247.24, 123.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 839)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (370, 1249, 2410)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6490)
[M::mem_pestat] mean and std.dev: (1497.82, 1591.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8530)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 246, 370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 762)
[M::mem_pestat] mean and std.dev: (266.56, 123.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 958)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704412 reads in 180.688 CPU sec, 5.848 real sec
[M::mem_process_seqs] Processed 704364 reads in 117.736 CPU sec, 3.736 real sec
sorting block 78, #reads = 1082458 mem = 536878264 peak = 1052041216
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 288396, 23, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 203, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 799)
[M::mem_pestat] mean and std.dev: (254.25, 151.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1015)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 223, 323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 665)
[M::mem_pestat] mean and std.dev: (247.83, 122.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 836)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (137, 470, 911)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2459)
[M::mem_pestat] mean and std.dev: (472.90, 377.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3233)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 268, 535)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1295)
[M::mem_pestat] mean and std.dev: (307.56, 207.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1675)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704020 sequences (100000055 bp) in 2.551 CPU sec, 2.591 real sec...
[M::process] read 704032 sequences (100000136 bp) in 1.990 CPU sec, 1.992 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (75, 288110, 9, 79)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (238, 344, 584)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1276)
[M::mem_pestat] mean and std.dev: (385.77, 213.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1622)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 222, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 662)
[M::mem_pestat] mean and std.dev: (246.88, 122.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 832)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 291, 476)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1060)
[M::mem_pestat] mean and std.dev: (309.61, 184.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1352)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703782 reads in 184.615 CPU sec, 5.853 real sec
sorting block 79, #reads = 1083052 mem = 536879852 peak = 1052041216
[M::mem_process_seqs] Processed 704300 reads in 123.432 CPU sec, 3.916 real sec
sorting block 80, #reads = 1081320 mem = 536879818 peak = 1052041216
[M::process] read 704452 sequences (100000018 bp) in 2.355 CPU sec, 2.431 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 288825, 15, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 312, 552)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1274)
[M::mem_pestat] mean and std.dev: (358.56, 236.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1635)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 222, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 662)
[M::mem_pestat] mean and std.dev: (246.66, 122.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 832)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (774, 1966, 4611)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12285)
[M::mem_pestat] mean and std.dev: (2988.67, 2948.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 16122)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 298, 403)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 863)
[M::mem_pestat] mean and std.dev: (291.91, 160.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1093)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704768 sequences (100000242 bp) in 1.830 CPU sec, 1.831 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (93, 288294, 26, 75)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 235, 438)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1012)
[M::mem_pestat] mean and std.dev: (240.90, 146.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1299)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 221, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 661)
[M::mem_pestat] mean and std.dev: (246.21, 122.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 831)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (238, 564, 1195)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3109)
[M::mem_pestat] mean and std.dev: (751.46, 570.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4066)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 314, 557)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1291)
[M::mem_pestat] mean and std.dev: (357.92, 253.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1658)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 288364, 21, 99)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 219, 393)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 845)
[M::mem_pestat] mean and std.dev: (293.40, 191.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1071)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 222, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 662)
[M::mem_pestat] mean and std.dev: (247.02, 122.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 832)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (28, 283, 870)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2554)
[M::mem_pestat] mean and std.dev: (353.53, 413.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3396)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 314, 448)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 930)
[M::mem_pestat] mean and std.dev: (306.51, 165.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1171)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704020 reads in 272.349 CPU sec, 8.938 real sec
[M::mem_process_seqs] Processed 704452 reads in 201.075 CPU sec, 6.443 real sec
[M::mem_process_seqs] Processed 704032 reads in 221.255 CPU sec, 7.117 real sec
sorting block 81, #reads = 1080307 mem = 536880029 peak = 1052041216
[M::process] read 712624 sequences (100000008 bp) in 2.835 CPU sec, 2.932 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 287963, 32, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 217, 598)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1438)
[M::mem_pestat] mean and std.dev: (307.65, 275.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1858)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 220, 319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 657)
[M::mem_pestat] mean and std.dev: (244.96, 122.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 826)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 622, 1871)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5177)
[M::mem_pestat] mean and std.dev: (1045.83, 1207.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6830)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 316, 496)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1098)
[M::mem_pestat] mean and std.dev: (336.13, 213.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1399)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 82, #reads = 1081168 mem = 536878192 peak = 1052041216
[M::process] read 711044 sequences (100000175 bp) in 2.403 CPU sec, 2.496 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 291260, 20, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 350, 740)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1832)
[M::mem_pestat] mean and std.dev: (393.20, 308.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2378)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (142, 203, 292)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 592)
[M::mem_pestat] mean and std.dev: (225.93, 109.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 742)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (259, 768, 1372)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3598)
[M::mem_pestat] mean and std.dev: (749.95, 669.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4711)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 245, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 634)
[M::mem_pestat] mean and std.dev: (254.52, 107.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 786)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704768 reads in 202.410 CPU sec, 6.452 real sec
[M::mem_process_seqs] Processed 712624 reads in 133.705 CPU sec, 4.205 real sec
[M::process] read 710144 sequences (100000274 bp) in 2.270 CPU sec, 2.351 real sec...
sorting block 83, #reads = 1075649 mem = 536879506 peak = 1052041216
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (73, 290526, 14, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 313, 481)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1075)
[M::mem_pestat] mean and std.dev: (285.26, 157.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1372)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (143, 206, 297)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 605)
[M::mem_pestat] mean and std.dev: (229.49, 112.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 759)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (713, 1209, 3056)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7742)
[M::mem_pestat] mean and std.dev: (1833.29, 1904.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10085)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (245, 305, 836)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2018)
[M::mem_pestat] mean and std.dev: (469.78, 429.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2609)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 711506 sequences (100000145 bp) in 2.579 CPU sec, 2.662 real sec...
[M::process] read 710014 sequences (100000253 bp) in 1.500 CPU sec, 1.496 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 290593, 28, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 238, 397)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 881)
[M::mem_pestat] mean and std.dev: (248.74, 135.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1123)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (144, 209, 302)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 618)
[M::mem_pestat] mean and std.dev: (233.14, 115.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 776)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (369, 839, 2047)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5403)
[M::mem_pestat] mean and std.dev: (882.78, 859.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7081)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 276, 598)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1466)
[M::mem_pestat] mean and std.dev: (343.53, 264.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1900)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 711044 reads in 183.435 CPU sec, 5.841 real sec
[M::mem_process_seqs] Processed 710144 reads in 119.798 CPU sec, 3.923 real sec
sorting block 84, #reads = 1084782 mem = 536878817 peak = 1052041216
[M::process] read 709626 sequences (100000051 bp) in 2.303 CPU sec, 2.416 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (77, 291572, 19, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 298, 437)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 919)
[M::mem_pestat] mean and std.dev: (316.12, 193.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1160)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (143, 205, 296)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 602)
[M::mem_pestat] mean and std.dev: (228.74, 111.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 755)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 398, 1492)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4096)
[M::mem_pestat] mean and std.dev: (1057.74, 1197.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5848)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 255, 423)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 957)
[M::mem_pestat] mean and std.dev: (277.47, 180.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1224)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 708228 sequences (100000245 bp) in 1.498 CPU sec, 1.509 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 291051, 20, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 273, 783)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1999)
[M::mem_pestat] mean and std.dev: (424.87, 427.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2607)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (144, 208, 301)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 615)
[M::mem_pestat] mean and std.dev: (232.39, 114.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 772)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (728, 921, 1349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2591)
[M::mem_pestat] mean and std.dev: (912.85, 514.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3212)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 287, 421)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 845)
[M::mem_pestat] mean and std.dev: (294.40, 131.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1057)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 290827, 27, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 308, 917)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2411)
[M::mem_pestat] mean and std.dev: (493.24, 497.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3158)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 209, 302)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 616)
[M::mem_pestat] mean and std.dev: (233.34, 115.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 773)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (229, 836, 2089)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5809)
[M::mem_pestat] mean and std.dev: (1084.24, 1242.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7669)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 273, 411)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 903)
[M::mem_pestat] mean and std.dev: (256.74, 147.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1149)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 711506 reads in 270.750 CPU sec, 8.759 real sec
sorting block 85, #reads = 1084706 mem = 536880376 peak = 1052041216
[M::mem_process_seqs] Processed 710014 reads in 200.597 CPU sec, 6.431 real sec
[M::mem_process_seqs] Processed 709626 reads in 221.447 CPU sec, 7.131 real sec
sorting block 86, #reads = 1083851 mem = 536879372 peak = 1052041216
[M::process] read 707260 sequences (100000136 bp) in 2.615 CPU sec, 2.725 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 289835, 24, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 214, 1079)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2939)
[M::mem_pestat] mean and std.dev: (526.04, 620.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3869)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 212, 310)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 638)
[M::mem_pestat] mean and std.dev: (238.02, 118.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 802)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (264, 622, 1765)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4767)
[M::mem_pestat] mean and std.dev: (864.77, 997.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6268)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 280, 449)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 935)
[M::mem_pestat] mean and std.dev: (290.75, 138.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1178)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706388 sequences (100000129 bp) in 2.248 CPU sec, 2.322 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 289564, 27, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 232, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 724)
[M::mem_pestat] mean and std.dev: (240.37, 125.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 915)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 215, 313)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 643)
[M::mem_pestat] mean and std.dev: (240.78, 120.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 808)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (136, 600, 1282)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3574)
[M::mem_pestat] mean and std.dev: (775.35, 802.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4720)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 302, 643)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1589)
[M::mem_pestat] mean and std.dev: (369.18, 314.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2062)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 708228 reads in 192.673 CPU sec, 6.130 real sec
[M::process] read 705210 sequences (100000266 bp) in 1.908 CPU sec, 1.948 real sec...
[M::mem_process_seqs] Processed 707260 reads in 127.717 CPU sec, 4.113 real sec
sorting block 87, #reads = 1084849 mem = 536878900 peak = 1052041216
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 288780, 22, 83)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 264, 487)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1085)
[M::mem_pestat] mean and std.dev: (309.02, 202.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1384)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 216, 315)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 647)
[M::mem_pestat] mean and std.dev: (241.90, 120.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 813)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 775, 1750)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4816)
[M::mem_pestat] mean and std.dev: (1178.91, 1226.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6349)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 315, 515)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1153)
[M::mem_pestat] mean and std.dev: (303.73, 172.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1472)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 88, #reads = 1082774 mem = 536880179 peak = 1052041216
[M::process] read 704874 sequences (100000137 bp) in 2.468 CPU sec, 2.567 real sec...
[M::process] read 704642 sequences (100000137 bp) in 1.600 CPU sec, 1.603 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 288879, 39, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 397, 897)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2365)
[M::mem_pestat] mean and std.dev: (471.94, 449.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3099)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 219, 319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 657)
[M::mem_pestat] mean and std.dev: (244.89, 122.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 826)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (451, 964, 3091)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8371)
[M::mem_pestat] mean and std.dev: (2119.87, 2324.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11419)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 349, 800)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2026)
[M::mem_pestat] mean and std.dev: (388.66, 278.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2639)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 706388 reads in 189.194 CPU sec, 6.112 real sec
[M::mem_process_seqs] Processed 705210 reads in 124.277 CPU sec, 3.953 real sec
sorting block 89, #reads = 1080640 mem = 536879512 peak = 1052041216
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 288493, 20, 77)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 257, 498)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1172)
[M::mem_pestat] mean and std.dev: (287.57, 216.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1509)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 219, 320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 658)
[M::mem_pestat] mean and std.dev: (245.37, 122.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 827)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (644, 1271, 2046)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4850)
[M::mem_pestat] mean and std.dev: (1477.16, 1217.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6347)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 252, 418)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 898)
[M::mem_pestat] mean and std.dev: (281.94, 171.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1138)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703684 sequences (100000187 bp) in 2.606 CPU sec, 2.727 real sec...
[M::process] read 703306 sequences (100000097 bp) in 1.900 CPU sec, 1.893 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 288169, 22, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 274, 498)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1140)
[M::mem_pestat] mean and std.dev: (314.30, 204.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1461)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 220, 319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 655)
[M::mem_pestat] mean and std.dev: (245.48, 122.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 823)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (395, 426, 1011)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2243)
[M::mem_pestat] mean and std.dev: (516.05, 269.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2859)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 231, 348)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 696)
[M::mem_pestat] mean and std.dev: (241.17, 103.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 870)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704874 reads in 184.010 CPU sec, 5.900 real sec
[M::mem_process_seqs] Processed 704642 reads in 118.920 CPU sec, 3.852 real sec
sorting block 90, #reads = 1081946 mem = 536879654 peak = 1052041216
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (81, 287998, 26, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 247, 416)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 938)
[M::mem_pestat] mean and std.dev: (286.08, 164.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1199)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 222, 323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 665)
[M::mem_pestat] mean and std.dev: (247.47, 122.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 836)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 641, 1203)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3279)
[M::mem_pestat] mean and std.dev: (681.78, 629.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4317)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 322, 821)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2029)
[M::mem_pestat] mean and std.dev: (511.42, 505.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2633)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702776 sequences (100000160 bp) in 2.571 CPU sec, 2.696 real sec...
[M::process] read 703380 sequences (100000297 bp) in 1.890 CPU sec, 1.890 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 288005, 21, 83)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 186, 372)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 818)
[M::mem_pestat] mean and std.dev: (233.98, 120.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1041)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 223, 323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 663)
[M::mem_pestat] mean and std.dev: (248.14, 122.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 833)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (648, 919, 1581)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3447)
[M::mem_pestat] mean and std.dev: (1093.05, 833.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4427)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 326, 515)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1169)
[M::mem_pestat] mean and std.dev: (347.80, 205.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1496)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703684 reads in 177.333 CPU sec, 5.705 real sec
[M::mem_process_seqs] Processed 703306 reads in 112.519 CPU sec, 3.629 real sec
sorting block 91, #reads = 1082596 mem = 536878517 peak = 1052041216
[M::process] read 703672 sequences (100000257 bp) in 2.433 CPU sec, 2.524 real sec...
[M::process] read 11082 sequences (1560442 bp) in 0.280 CPU sec, 0.282 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 288061, 25, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 294, 619)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1457)
[M::mem_pestat] mean and std.dev: (353.71, 245.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1876)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 224, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 674)
[M::mem_pestat] mean and std.dev: (249.12, 124.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 848)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (293, 628, 1177)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2945)
[M::mem_pestat] mean and std.dev: (658.56, 453.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3829)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 283, 693)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1651)
[M::mem_pestat] mean and std.dev: (419.66, 322.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2130)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703380 reads in 94.651 CPU sec, 3.036 real sec
sorting block 92, #reads = 1082833 mem = 536880324 peak = 1052041216
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 287957, 14, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 319, 837)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2081)
[M::mem_pestat] mean and std.dev: (424.60, 369.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2703)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 225, 327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 675)
[M::mem_pestat] mean and std.dev: (250.34, 124.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 849)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (524, 4259, 7562)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 21638)
[M::mem_pestat] mean and std.dev: (3419.07, 3182.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 28676)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 255, 371)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 727)
[M::mem_pestat] mean and std.dev: (263.37, 112.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 905)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 287746, 22, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 320, 445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 941)
[M::mem_pestat] mean and std.dev: (279.54, 122.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1189)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 223, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 668)
[M::mem_pestat] mean and std.dev: (248.50, 123.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 840)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (131, 646, 1201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3341)
[M::mem_pestat] mean and std.dev: (932.86, 955.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4754)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 320, 519)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1117)
[M::mem_pestat] mean and std.dev: (306.96, 157.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1416)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702776 reads in 278.467 CPU sec, 9.027 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (1, 4539, 1, 1)
[M::mem_pestat] skip orientation FF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (144, 212, 308)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 636)
[M::mem_pestat] mean and std.dev: (236.31, 117.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 800)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] skip orientation RR as there are not enough pairs
[M::mem_process_seqs] Processed 11082 reads in 2.087 CPU sec, 0.077 real sec
[M::mem_process_seqs] Processed 703672 reads in 142.271 CPU sec, 4.624 real sec
sorting block 93, #reads = 1082865 mem = 536879581 peak = 1090809856
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000a06d1
  features: bfebfbff 7ffefbff
  extended: f3bfb7ef fb417ffe
  amd bits: 2c100800 00000121
     brand: Intel(R) Xeon(R) 6975P-C
threads: 31
algo: bwa-mem
license: sentieon:klib=31
reads: 102178026
overall: 70113521664 mem 15881.940 user 451.688 sys 541.804 real
[main] Version: 0.7.17-r1188
[main] CMD: /opt/conda/share/sentieon-202308.03-3/libexec/bwa mem -K 100000000 -Y -R @RG\tID:A23MHWWLT4.1136_4ZB-T1-TDNA-1_A23MHWWLT4_1.L002\tPU:L002\tSM:1136_4ZB-T1-TDNA-1_A23MHWWLT4_1\tLB:1136_4ZB-T1-TDNA-1_A23MHWWLT4_1\tDS:s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta\tPL:ILLUMINA -t 31 ./BWAIndex/Homo_sapiens_assembly38.fasta.64 1136_4ZB-T1-TDNA-1_A23MHWWLT4_1_R1.fastq.gz 1136_4ZB-T1-TDNA-1_A23MHWWLT4_1_R2.fastq.gz
[main] Real time: 541.837 sec; CPU: 16333.631 sec
sorting block 94, #reads = 1019718 mem = 506625385 peak = 1120649216
uniq header count 1
merging 95 blocks
sw version: sentieon-genomics-202308.03
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000a06d1
  features: bfebfbff 7ffefbff
  extended: f3bfb7ef fb417ffe
  amd bits: 2c100800 00000121
     brand: Intel(R) Xeon(R) 6975P-C
threads: 31 max 192
algo: util-sort
license: sentieon:util=1
output file size: 5531562160
output reads: 102909973
bam_mem_sort: 95 calls 54.618 user 1.749 sys 56.596 real
bam_write: 95 calls 29.515 user 2.274 sys 36.641 real
execute: 1 calls 31.621 user 1.394 sys 577.942 real
merge_files: 1 calls 31.601 user 1.371 sys 34.920 real
parse_chunk: 1520 calls 63.010 user 15.532 sys 81.453 real
read_chunk: 4111 calls 35.862 user 32.771 sys 479.228 real
sort_block: 1 calls 24.716 user 32.244 sys 463.316 real
write_chunk: 2589 calls 31.018 user 1.040 sys 33.718 real
overall: 3067224064 mem 1349.016 user 67.185 sys 577.961 real
ls: cannot access '*.cram': No such file or directory