This software is licensed to bgold@natera.com by Sentieon Inc. cmdline: /opt/conda/share/sentieon-202308.03-3/libexec/util sort -r Homo_sapiens_assembly38.fasta -t 31 -o 1136_76X-T1-TDNA-1_A23MHWWLT4_1.bam --sam2bam - This software is licensed to bgold@natera.com by Sentieon Inc. version: sentieon-genomics-202308.03 [M::bwa_idx_load_from_disk] read 3171 ALT contigs [M::main_mem] bwa index loaded in 1707.476 CPU sec, 57.911 real sec [M::process] read 704404 sequences (100000190 bp) in 0.910 CPU sec, 0.919 real sec... [M::process] read 703362 sequences (100000089 bp) in 1.450 CPU sec, 1.441 real sec... [M::process] read 703866 sequences (100000272 bp) in 1.505 CPU sec, 1.514 real sec... [M::process] read 702904 sequences (100000252 bp) in 1.522 CPU sec, 1.529 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 281029, 37, 25) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (233, 310, 1173) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3053) [M::mem_pestat] mean and std.dev: (506.77, 641.57) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3993) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (154, 229, 330) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 682) [M::mem_pestat] mean and std.dev: (251.83, 124.19) [M::mem_pestat] low and high boundaries for proper pairs: (1, 858) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (158, 546, 2121) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6047) [M::mem_pestat] mean and std.dev: (1067.71, 1186.70) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8010) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (168, 214, 1345) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3699) [M::mem_pestat] mean and std.dev: (635.83, 751.57) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4876) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 703362 reads in 106.039 CPU sec, 3.355 real sec [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 281005, 17, 51) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (176, 241, 493) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1127) [M::mem_pestat] mean and std.dev: (293.47, 179.96) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1444) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (154, 228, 328) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 676) [M::mem_pestat] mean and std.dev: (250.51, 123.52) [M::mem_pestat] low and high boundaries for proper pairs: (1, 850) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (317, 828, 1430) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3656) [M::mem_pestat] mean and std.dev: (735.80, 683.87) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4769) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (191, 417, 850) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2168) [M::mem_pestat] mean and std.dev: (485.36, 373.22) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2827) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 701924 sequences (100000087 bp) in 1.673 CPU sec, 1.690 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 281066, 21, 54) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (216, 356, 649) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1515) [M::mem_pestat] mean and std.dev: (380.66, 272.46) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1948) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (155, 229, 331) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 683) [M::mem_pestat] mean and std.dev: (252.56, 125.14) [M::mem_pestat] low and high boundaries for proper pairs: (1, 859) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (806, 1118, 2732) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6584) [M::mem_pestat] mean and std.dev: (1645.86, 1123.75) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8510) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (255, 462, 1214) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3132) [M::mem_pestat] mean and std.dev: (897.37, 894.10) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4474) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 704404 reads in 278.098 CPU sec, 8.811 real sec sorting block 0, #reads = 1071723 mem = 536882168 peak = 635039744 [M::mem_process_seqs] Processed 703866 reads in 150.487 CPU sec, 4.869 real sec [M::process] read 701484 sequences (100000287 bp) in 1.900 CPU sec, 2.254 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 281217, 28, 51) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (130, 266, 742) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1966) [M::mem_pestat] mean and std.dev: (375.94, 282.00) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2578) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (155, 230, 333) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 689) [M::mem_pestat] mean and std.dev: (254.10, 125.78) [M::mem_pestat] low and high boundaries for proper pairs: (1, 867) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (368, 1175, 2265) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6059) [M::mem_pestat] mean and std.dev: (1262.71, 973.83) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7956) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (214, 353, 658) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1546) [M::mem_pestat] mean and std.dev: (439.38, 343.36) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1990) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 700956 sequences (100000253 bp) in 1.623 CPU sec, 1.625 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 280892, 32, 43) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (230, 339, 877) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2171) [M::mem_pestat] mean and std.dev: (478.82, 367.24) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2818) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (157, 232, 337) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 697) [M::mem_pestat] mean and std.dev: (256.58, 127.26) [M::mem_pestat] low and high boundaries for proper pairs: (1, 877) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (437, 977, 1506) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3644) [M::mem_pestat] mean and std.dev: (999.03, 727.95) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4713) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (293, 454, 1132) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2810) [M::mem_pestat] mean and std.dev: (672.44, 575.07) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3649) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 280768, 14, 49) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (222, 364, 710) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1686) [M::mem_pestat] mean and std.dev: (420.47, 297.02) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2174) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (158, 235, 339) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 701) [M::mem_pestat] mean and std.dev: (258.28, 127.83) [M::mem_pestat] low and high boundaries for proper pairs: (1, 882) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (150, 920, 1460) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4080) [M::mem_pestat] mean and std.dev: (807.15, 761.10) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5390) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (161, 293, 1009) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2705) [M::mem_pestat] mean and std.dev: (481.07, 514.37) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3553) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 702904 reads in 260.333 CPU sec, 8.406 real sec sorting block 1, #reads = 1070269 mem = 536877185 peak = 929181696 [M::mem_process_seqs] Processed 701924 reads in 203.270 CPU sec, 6.540 real sec [M::mem_process_seqs] Processed 701484 reads in 228.585 CPU sec, 7.385 real sec sorting block 2, #reads = 1070563 mem = 536879560 peak = 972099584 [M::process] read 701040 sequences (100000084 bp) in 2.053 CPU sec, 2.361 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 280469, 19, 42) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (195, 396, 1705) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4725) [M::mem_pestat] mean and std.dev: (760.41, 787.17) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6235) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (158, 236, 341) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 707) [M::mem_pestat] mean and std.dev: (260.09, 129.49) [M::mem_pestat] low and high boundaries for proper pairs: (1, 890) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (107, 1329, 2916) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8534) [M::mem_pestat] mean and std.dev: (2010.21, 2152.95) [M::mem_pestat] low and high boundaries for proper pairs: (1, 11343) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (263, 702, 1051) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2627) [M::mem_pestat] mean and std.dev: (717.32, 564.76) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3415) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 700760 sequences (100000262 bp) in 2.044 CPU sec, 2.315 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 280226, 22, 56) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (148, 687, 1730) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4894) [M::mem_pestat] mean and std.dev: (860.03, 837.50) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6476) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (159, 236, 343) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 711) [M::mem_pestat] mean and std.dev: (260.96, 130.15) [M::mem_pestat] low and high boundaries for proper pairs: (1, 895) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (394, 1153, 3425) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9487) [M::mem_pestat] mean and std.dev: (2124.32, 2178.39) [M::mem_pestat] low and high boundaries for proper pairs: (1, 12518) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (162, 305, 446) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1014) [M::mem_pestat] mean and std.dev: (287.98, 161.85) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1298) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 700348 sequences (100000058 bp) in 1.640 CPU sec, 1.647 real sec... [M::mem_process_seqs] Processed 700956 reads in 184.523 CPU sec, 5.999 real sec sorting block 3, #reads = 1069638 mem = 536877563 peak = 972099584 [M::mem_process_seqs] Processed 701040 reads in 128.215 CPU sec, 4.145 real sec sorting block 4, #reads = 1070698 mem = 536879151 peak = 972099584 [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 280329, 24, 61) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (297, 697, 1634) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4308) [M::mem_pestat] mean and std.dev: (996.10, 848.52) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5645) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (159, 236, 344) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 714) [M::mem_pestat] mean and std.dev: (261.69, 130.98) [M::mem_pestat] low and high boundaries for proper pairs: (1, 899) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (305, 587, 1855) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4955) [M::mem_pestat] mean and std.dev: (1018.82, 1350.81) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6505) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (230, 559, 1215) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3185) [M::mem_pestat] mean and std.dev: (700.44, 541.69) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4170) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 699810 sequences (100000033 bp) in 2.106 CPU sec, 2.333 real sec... [M::process] read 699922 sequences (100000252 bp) in 1.660 CPU sec, 1.740 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 280484, 18, 69) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (196, 257, 929) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2395) [M::mem_pestat] mean and std.dev: (393.65, 370.38) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3128) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (160, 238, 344) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 712) [M::mem_pestat] mean and std.dev: (262.22, 130.39) [M::mem_pestat] low and high boundaries for proper pairs: (1, 896) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (222, 728, 1319) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3513) [M::mem_pestat] mean and std.dev: (796.59, 752.21) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4610) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (187, 306, 689) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1693) [M::mem_pestat] mean and std.dev: (377.77, 345.12) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2195) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 700760 reads in 180.753 CPU sec, 6.039 real sec [M::mem_process_seqs] Processed 700348 reads in 126.380 CPU sec, 4.170 real sec sorting block 5, #reads = 1069638 mem = 536877741 peak = 972099584 [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 279717, 30, 47) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (203, 454, 1145) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3029) [M::mem_pestat] mean and std.dev: (695.35, 625.21) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3971) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (160, 238, 344) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 712) [M::mem_pestat] mean and std.dev: (262.44, 130.53) [M::mem_pestat] low and high boundaries for proper pairs: (1, 896) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (859, 2355, 2908) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7006) [M::mem_pestat] mean and std.dev: (1970.69, 1302.82) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9055) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (218, 764, 2000) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5564) [M::mem_pestat] mean and std.dev: (1259.74, 1407.96) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7346) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 699472 sequences (100000151 bp) in 2.121 CPU sec, 2.300 real sec... [M::process] read 700032 sequences (100000012 bp) in 1.719 CPU sec, 1.736 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 279512, 30, 49) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (175, 395, 1143) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3079) [M::mem_pestat] mean and std.dev: (581.14, 551.91) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4047) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (160, 237, 341) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 703) [M::mem_pestat] mean and std.dev: (260.84, 128.85) [M::mem_pestat] low and high boundaries for proper pairs: (1, 884) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (265, 762, 1914) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5212) [M::mem_pestat] mean and std.dev: (827.04, 713.64) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6861) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (238, 385, 721) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1687) [M::mem_pestat] mean and std.dev: (387.95, 284.71) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2170) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 699810 reads in 185.981 CPU sec, 6.076 real sec sorting block 6, #reads = 1069469 mem = 536886500 peak = 972099584 [M::mem_process_seqs] Processed 699922 reads in 128.930 CPU sec, 4.148 real sec [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 279847, 31, 40) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (203, 548, 1306) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3512) [M::mem_pestat] mean and std.dev: (676.24, 615.99) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4615) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (161, 239, 343) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 707) [M::mem_pestat] mean and std.dev: (262.06, 129.06) [M::mem_pestat] low and high boundaries for proper pairs: (1, 889) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (449, 1144, 1522) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3668) [M::mem_pestat] mean and std.dev: (1110.00, 819.48) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4741) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (221, 381, 573) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1277) [M::mem_pestat] mean and std.dev: (368.77, 225.74) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1629) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 700114 sequences (100000287 bp) in 2.247 CPU sec, 2.657 real sec... [M::process] read 700194 sequences (100000119 bp) in 1.652 CPU sec, 1.670 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 279923, 32, 39) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (255, 839, 1191) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3063) [M::mem_pestat] mean and std.dev: (770.92, 630.81) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3999) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (159, 236, 341) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 705) [M::mem_pestat] mean and std.dev: (260.75, 129.40) [M::mem_pestat] low and high boundaries for proper pairs: (1, 887) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (232, 665, 1003) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2545) [M::mem_pestat] mean and std.dev: (580.79, 444.35) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3316) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (206, 534, 1389) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3755) [M::mem_pestat] mean and std.dev: (832.46, 818.07) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4938) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 699472 reads in 180.696 CPU sec, 5.855 real sec sorting block 7, #reads = 1068305 mem = 536881643 peak = 972099584 [M::mem_process_seqs] Processed 700032 reads in 126.411 CPU sec, 4.295 real sec sorting block 8, #reads = 1068659 mem = 536883353 peak = 972099584 [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 279776, 36, 51) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (204, 417, 1289) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3459) [M::mem_pestat] mean and std.dev: (797.31, 753.25) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4544) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (160, 236, 340) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 700) [M::mem_pestat] mean and std.dev: (260.03, 128.37) [M::mem_pestat] low and high boundaries for proper pairs: (1, 880) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (246, 932, 1839) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5025) [M::mem_pestat] mean and std.dev: (1193.38, 1120.27) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6618) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (306, 752, 3001) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8391) [M::mem_pestat] mean and std.dev: (2359.37, 2972.64) [M::mem_pestat] low and high boundaries for proper pairs: (1, 14250) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 699408 sequences (100000146 bp) in 2.198 CPU sec, 2.427 real sec... [M::process] read 699268 sequences (100000111 bp) in 1.791 CPU sec, 1.798 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 279776, 16, 51) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (156, 297, 1243) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3417) [M::mem_pestat] mean and std.dev: (560.05, 743.01) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4504) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (159, 236, 340) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 702) [M::mem_pestat] mean and std.dev: (260.07, 128.75) [M::mem_pestat] low and high boundaries for proper pairs: (1, 883) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (194, 531, 2361) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6695) [M::mem_pestat] mean and std.dev: (1042.67, 1268.65) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8862) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (210, 395, 942) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2406) [M::mem_pestat] mean and std.dev: (488.28, 370.67) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3138) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 700114 reads in 186.726 CPU sec, 6.220 real sec [M::mem_process_seqs] Processed 700194 reads in 128.698 CPU sec, 4.145 real sec sorting block 9, #reads = 1069553 mem = 536881844 peak = 972099584 [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 280013, 28, 37) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (202, 513, 1563) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4285) [M::mem_pestat] mean and std.dev: (913.57, 853.43) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5646) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (161, 238, 343) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 707) [M::mem_pestat] mean and std.dev: (261.87, 129.09) [M::mem_pestat] low and high boundaries for proper pairs: (1, 889) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (789, 1143, 2316) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5370) [M::mem_pestat] mean and std.dev: (1625.25, 1165.89) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6897) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (218, 324, 699) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1661) [M::mem_pestat] mean and std.dev: (429.94, 351.83) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2142) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 698986 sequences (100000287 bp) in 2.377 CPU sec, 2.590 real sec... [M::process] read 698346 sequences (100000058 bp) in 1.788 CPU sec, 1.798 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 279647, 29, 45) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (151, 308, 739) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1915) [M::mem_pestat] mean and std.dev: (412.72, 415.87) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2503) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (160, 239, 345) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 715) [M::mem_pestat] mean and std.dev: (263.16, 130.40) [M::mem_pestat] low and high boundaries for proper pairs: (1, 900) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (288, 685, 1405) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3639) [M::mem_pestat] mean and std.dev: (644.80, 517.56) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4756) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (178, 500, 1266) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3442) [M::mem_pestat] mean and std.dev: (865.27, 911.85) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4530) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 699408 reads in 186.046 CPU sec, 6.078 real sec [M::mem_process_seqs] Processed 699268 reads in 127.667 CPU sec, 4.201 real sec sorting block 10, #reads = 1068636 mem = 536878934 peak = 975253504 [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 279425, 27, 57) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (191, 492, 1046) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2756) [M::mem_pestat] mean and std.dev: (585.58, 611.96) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3611) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (161, 240, 344) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 710) [M::mem_pestat] mean and std.dev: (262.80, 129.19) [M::mem_pestat] low and high boundaries for proper pairs: (1, 893) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (314, 565, 2877) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8003) [M::mem_pestat] mean and std.dev: (1361.62, 1440.57) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10566) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (250, 386, 1002) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2506) [M::mem_pestat] mean and std.dev: (557.09, 526.39) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3258) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 698372 sequences (100000288 bp) in 2.122 CPU sec, 2.486 real sec... [M::process] read 697926 sequences (100000261 bp) in 1.892 CPU sec, 1.897 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 279332, 42, 50) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (161, 290, 785) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2033) [M::mem_pestat] mean and std.dev: (504.38, 479.64) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2657) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (163, 242, 347) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 715) [M::mem_pestat] mean and std.dev: (264.86, 130.04) [M::mem_pestat] low and high boundaries for proper pairs: (1, 899) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (386, 1114, 3500) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9728) [M::mem_pestat] mean and std.dev: (2193.33, 2812.29) [M::mem_pestat] low and high boundaries for proper pairs: (1, 13443) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (272, 406, 1068) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2660) [M::mem_pestat] mean and std.dev: (588.43, 450.72) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3456) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 698986 reads in 185.667 CPU sec, 6.095 real sec sorting block 11, #reads = 1068236 mem = 536878780 peak = 975253504 [M::mem_process_seqs] Processed 698346 reads in 127.365 CPU sec, 4.104 real sec [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 278931, 20, 41) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (177, 262, 502) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1152) [M::mem_pestat] mean and std.dev: (269.07, 147.17) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1477) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (163, 242, 348) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 718) [M::mem_pestat] mean and std.dev: (265.41, 130.28) [M::mem_pestat] low and high boundaries for proper pairs: (1, 903) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (626, 989, 1311) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2681) [M::mem_pestat] mean and std.dev: (844.28, 515.98) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3366) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (225, 325, 1227) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3231) [M::mem_pestat] mean and std.dev: (623.24, 649.38) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4233) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR sorting block 12, #reads = 1068623 mem = 536877586 peak = 1009647616 [M::process] read 698226 sequences (100000067 bp) in 2.292 CPU sec, 2.734 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 279232, 23, 57) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (204, 449, 1008) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2616) [M::mem_pestat] mean and std.dev: (594.30, 544.14) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3420) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (163, 243, 348) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 718) [M::mem_pestat] mean and std.dev: (266.04, 130.65) [M::mem_pestat] low and high boundaries for proper pairs: (1, 903) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (357, 493, 1670) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4296) [M::mem_pestat] mean and std.dev: (971.55, 1034.98) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5609) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (235, 545, 1099) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2827) [M::mem_pestat] mean and std.dev: (590.08, 530.31) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3691) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 697664 sequences (100000265 bp) in 1.579 CPU sec, 1.622 real sec... [M::mem_process_seqs] Processed 698372 reads in 186.078 CPU sec, 6.134 real sec [M::mem_process_seqs] Processed 697926 reads in 126.833 CPU sec, 4.109 real sec sorting block 13, #reads = 1067433 mem = 536879577 peak = 1009647616 [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 279174, 29, 47) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (196, 524, 2922) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8374) [M::mem_pestat] mean and std.dev: (1373.55, 2035.55) [M::mem_pestat] low and high boundaries for proper pairs: (1, 11100) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (163, 243, 350) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 724) [M::mem_pestat] mean and std.dev: (266.55, 131.17) [M::mem_pestat] low and high boundaries for proper pairs: (1, 911) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (192, 760, 1761) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4899) [M::mem_pestat] mean and std.dev: (983.14, 929.63) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6468) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (257, 496, 1297) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3377) [M::mem_pestat] mean and std.dev: (657.69, 609.48) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4417) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 697426 sequences (100000094 bp) in 2.177 CPU sec, 2.773 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 279024, 15, 51) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (304, 932, 1671) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4405) [M::mem_pestat] mean and std.dev: (871.12, 810.84) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5772) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (164, 245, 353) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 731) [M::mem_pestat] mean and std.dev: (268.83, 132.63) [M::mem_pestat] low and high boundaries for proper pairs: (1, 920) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (739, 1158, 4289) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 11389) [M::mem_pestat] mean and std.dev: (2093.33, 1889.79) [M::mem_pestat] low and high boundaries for proper pairs: (1, 14939) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (233, 503, 828) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2018) [M::mem_pestat] mean and std.dev: (549.15, 370.32) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2613) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 703204 sequences (100000262 bp) in 1.795 CPU sec, 1.797 real sec... [M::mem_process_seqs] Processed 698226 reads in 183.909 CPU sec, 5.988 real sec [M::mem_process_seqs] Processed 697664 reads in 125.874 CPU sec, 4.148 real sec sorting block 14, #reads = 1067869 mem = 536878486 peak = 1009647616 [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 279350, 34, 45) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (156, 365, 922) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2454) [M::mem_pestat] mean and std.dev: (428.03, 469.00) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3220) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (165, 246, 355) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 735) [M::mem_pestat] mean and std.dev: (269.69, 132.99) [M::mem_pestat] low and high boundaries for proper pairs: (1, 925) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (167, 456, 2607) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7487) [M::mem_pestat] mean and std.dev: (1294.82, 1338.23) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9927) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (219, 359, 2006) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5580) [M::mem_pestat] mean and std.dev: (1032.22, 1327.03) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7367) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 704328 sequences (100000199 bp) in 2.400 CPU sec, 2.906 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 280881, 26, 51) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (151, 222, 639) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1615) [M::mem_pestat] mean and std.dev: (273.14, 221.36) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2103) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (155, 230, 333) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 689) [M::mem_pestat] mean and std.dev: (254.23, 126.23) [M::mem_pestat] low and high boundaries for proper pairs: (1, 867) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (366, 954, 2236) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5976) [M::mem_pestat] mean and std.dev: (1250.42, 1153.76) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7846) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (178, 289, 633) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1543) [M::mem_pestat] mean and std.dev: (342.66, 279.66) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1998) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 703876 sequences (100000101 bp) in 1.664 CPU sec, 1.670 real sec... [M::mem_process_seqs] Processed 697426 reads in 188.593 CPU sec, 6.205 real sec sorting block 15, #reads = 1067584 mem = 536879973 peak = 1009647616 [M::mem_process_seqs] Processed 703204 reads in 132.956 CPU sec, 4.267 real sec [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 281717, 23, 43) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (170, 328, 876) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2288) [M::mem_pestat] mean and std.dev: (469.61, 402.70) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2994) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (154, 228, 331) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 685) [M::mem_pestat] mean and std.dev: (252.67, 126.22) [M::mem_pestat] low and high boundaries for proper pairs: (1, 862) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (495, 978, 1118) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2364) [M::mem_pestat] mean and std.dev: (880.18, 595.98) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3264) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (181, 515, 1462) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4024) [M::mem_pestat] mean and std.dev: (714.55, 605.38) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5305) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR sorting block 16, #reads = 1067333 mem = 536882731 peak = 1017102336 [M::process] read 703294 sequences (100000101 bp) in 2.376 CPU sec, 2.744 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 281062, 25, 38) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (247, 509, 1606) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4324) [M::mem_pestat] mean and std.dev: (855.18, 724.65) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5683) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (154, 229, 333) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 691) [M::mem_pestat] mean and std.dev: (253.98, 127.17) [M::mem_pestat] low and high boundaries for proper pairs: (1, 870) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (207, 566, 2195) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6171) [M::mem_pestat] mean and std.dev: (919.83, 1202.30) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8159) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (283, 510, 1245) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3169) [M::mem_pestat] mean and std.dev: (713.50, 549.76) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4131) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 702492 sequences (100000187 bp) in 1.802 CPU sec, 1.817 real sec... [M::mem_process_seqs] Processed 704328 reads in 179.666 CPU sec, 5.823 real sec [M::mem_process_seqs] Processed 703876 reads in 125.987 CPU sec, 4.128 real sec sorting block 17, #reads = 1073684 mem = 536880483 peak = 1017102336 [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 281206, 22, 45) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (283, 769, 1431) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3727) [M::mem_pestat] mean and std.dev: (692.38, 519.36) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4875) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (155, 231, 335) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 695) [M::mem_pestat] mean and std.dev: (255.24, 127.51) [M::mem_pestat] low and high boundaries for proper pairs: (1, 875) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (242, 946, 1584) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4268) [M::mem_pestat] mean and std.dev: (1104.90, 997.23) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5610) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (192, 394, 1563) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4305) [M::mem_pestat] mean and std.dev: (840.76, 1029.27) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5676) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 702346 sequences (100000103 bp) in 2.241 CPU sec, 2.787 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 281384, 22, 41) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (171, 219, 972) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2574) [M::mem_pestat] mean and std.dev: (495.54, 574.43) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3375) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (156, 231, 337) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 699) [M::mem_pestat] mean and std.dev: (256.55, 128.03) [M::mem_pestat] low and high boundaries for proper pairs: (1, 880) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (300, 881, 2517) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6951) [M::mem_pestat] mean and std.dev: (1424.86, 1442.07) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9168) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (159, 269, 669) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1689) [M::mem_pestat] mean and std.dev: (302.06, 203.91) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2199) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 701578 sequences (100000139 bp) in 1.670 CPU sec, 1.688 real sec... [M::mem_process_seqs] Processed 703294 reads in 183.735 CPU sec, 6.026 real sec [M::mem_process_seqs] Processed 702492 reads in 124.933 CPU sec, 4.132 real sec sorting block 18, #reads = 1072989 mem = 536890539 peak = 1017102336 [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 281056, 25, 52) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (272, 372, 1949) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5303) [M::mem_pestat] mean and std.dev: (894.33, 1022.73) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6980) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (156, 232, 338) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 702) [M::mem_pestat] mean and std.dev: (257.29, 128.63) [M::mem_pestat] low and high boundaries for proper pairs: (1, 884) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (287, 473, 1374) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3548) [M::mem_pestat] mean and std.dev: (762.61, 752.79) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4635) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (288, 756, 969) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2331) [M::mem_pestat] mean and std.dev: (637.19, 443.06) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3012) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 701390 sequences (100000029 bp) in 2.297 CPU sec, 2.753 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 281053, 30, 55) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (166, 571, 1282) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3514) [M::mem_pestat] mean and std.dev: (649.98, 630.64) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4630) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (158, 236, 343) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 713) [M::mem_pestat] mean and std.dev: (260.79, 130.65) [M::mem_pestat] low and high boundaries for proper pairs: (1, 898) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (141, 218, 2243) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6447) [M::mem_pestat] mean and std.dev: (1057.96, 1488.11) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8549) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (249, 380, 1235) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3207) [M::mem_pestat] mean and std.dev: (609.81, 560.64) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4193) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 701116 sequences (100000026 bp) in 1.798 CPU sec, 1.872 real sec... [M::mem_process_seqs] Processed 702346 reads in 182.777 CPU sec, 6.017 real sec sorting block 19, #reads = 1071102 mem = 536880125 peak = 1017102336 [M::mem_process_seqs] Processed 701578 reads in 124.038 CPU sec, 4.045 real sec [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 280628, 41, 61) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (189, 330, 623) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1491) [M::mem_pestat] mean and std.dev: (488.56, 413.33) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2142) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (158, 236, 343) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 713) [M::mem_pestat] mean and std.dev: (260.98, 130.71) [M::mem_pestat] low and high boundaries for proper pairs: (1, 898) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (280, 318, 1071) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2653) [M::mem_pestat] mean and std.dev: (590.46, 611.42) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3444) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (185, 388, 965) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2525) [M::mem_pestat] mean and std.dev: (570.07, 565.35) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3305) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR sorting block 20, #reads = 1071840 mem = 536877763 peak = 1017102336 [M::process] read 701250 sequences (100000151 bp) in 2.443 CPU sec, 2.743 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 280959, 34, 38) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (292, 438, 881) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2059) [M::mem_pestat] mean and std.dev: (626.39, 496.64) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2648) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (158, 237, 345) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 719) [M::mem_pestat] mean and std.dev: (262.16, 131.59) [M::mem_pestat] low and high boundaries for proper pairs: (1, 906) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (367, 562, 1274) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3088) [M::mem_pestat] mean and std.dev: (783.91, 624.09) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3995) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (174, 350, 1330) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3642) [M::mem_pestat] mean and std.dev: (847.08, 1052.94) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5059) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 700912 sequences (100000098 bp) in 1.692 CPU sec, 1.745 real sec... [M::mem_process_seqs] Processed 701390 reads in 184.393 CPU sec, 6.017 real sec [M::mem_process_seqs] Processed 701116 reads in 125.658 CPU sec, 4.066 real sec sorting block 21, #reads = 1072298 mem = 536881699 peak = 1017102336 [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 280204, 26, 55) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (157, 414, 1720) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4846) [M::mem_pestat] mean and std.dev: (870.27, 884.43) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6409) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (158, 236, 344) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 716) [M::mem_pestat] mean and std.dev: (261.55, 131.13) [M::mem_pestat] low and high boundaries for proper pairs: (1, 902) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (411, 1314, 2497) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6669) [M::mem_pestat] mean and std.dev: (1524.80, 1387.40) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8755) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (266, 471, 1294) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3350) [M::mem_pestat] mean and std.dev: (722.61, 593.22) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4378) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 700800 sequences (100000095 bp) in 2.484 CPU sec, 2.880 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 280323, 27, 51) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (199, 387, 969) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2509) [M::mem_pestat] mean and std.dev: (514.05, 515.66) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3279) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (159, 237, 346) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 720) [M::mem_pestat] mean and std.dev: (262.50, 131.95) [M::mem_pestat] low and high boundaries for proper pairs: (1, 907) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (232, 686, 1062) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2722) [M::mem_pestat] mean and std.dev: (693.30, 571.15) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3552) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (215, 353, 888) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2234) [M::mem_pestat] mean and std.dev: (518.28, 516.24) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2907) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 700766 sequences (100000048 bp) in 1.790 CPU sec, 1.984 real sec... [M::mem_process_seqs] Processed 701250 reads in 181.657 CPU sec, 5.907 real sec [M::mem_process_seqs] Processed 700912 reads in 126.796 CPU sec, 4.375 real sec sorting block 22, #reads = 1070461 mem = 536882735 peak = 1017102336 [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 280653, 33, 64) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (145, 284, 703) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1819) [M::mem_pestat] mean and std.dev: (395.43, 352.07) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2377) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (158, 236, 344) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 716) [M::mem_pestat] mean and std.dev: (261.46, 131.36) [M::mem_pestat] low and high boundaries for proper pairs: (1, 902) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (250, 772, 1860) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5080) [M::mem_pestat] mean and std.dev: (1195.33, 1157.09) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6690) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (256, 407, 967) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2389) [M::mem_pestat] mean and std.dev: (528.42, 451.00) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3100) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 700294 sequences (100000094 bp) in 2.429 CPU sec, 2.835 real sec... [M::process] read 700614 sequences (100000262 bp) in 1.625 CPU sec, 1.628 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 280424, 29, 57) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (249, 516, 1377) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3633) [M::mem_pestat] mean and std.dev: (861.97, 764.17) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4761) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (159, 236, 343) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 711) [M::mem_pestat] mean and std.dev: (261.41, 130.80) [M::mem_pestat] low and high boundaries for proper pairs: (1, 895) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (370, 892, 1061) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2443) [M::mem_pestat] mean and std.dev: (732.85, 443.78) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3134) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (238, 470, 1732) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4720) [M::mem_pestat] mean and std.dev: (895.61, 904.96) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6214) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 700800 reads in 188.002 CPU sec, 6.321 real sec sorting block 23, #reads = 1069554 mem = 536877354 peak = 1017102336 [M::mem_process_seqs] Processed 700766 reads in 129.162 CPU sec, 4.229 real sec [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 279704, 24, 50) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (253, 364, 514) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1036) [M::mem_pestat] mean and std.dev: (305.96, 134.20) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1297) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (159, 236, 341) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 705) [M::mem_pestat] mean and std.dev: (260.12, 128.75) [M::mem_pestat] low and high boundaries for proper pairs: (1, 887) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (132, 341, 914) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2478) [M::mem_pestat] mean and std.dev: (624.46, 691.01) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3388) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (205, 305, 1188) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3154) [M::mem_pestat] mean and std.dev: (583.20, 568.08) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4137) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR sorting block 24, #reads = 1068592 mem = 536879043 peak = 1065345024 [M::process] read 700400 sequences (100000015 bp) in 2.376 CPU sec, 2.909 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 280229, 26, 50) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (275, 397, 1229) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3137) [M::mem_pestat] mean and std.dev: (651.27, 671.37) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4091) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (159, 235, 340) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 702) [M::mem_pestat] mean and std.dev: (259.30, 127.99) [M::mem_pestat] low and high boundaries for proper pairs: (1, 883) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (749, 1337, 3378) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8636) [M::mem_pestat] mean and std.dev: (1856.62, 1568.23) [M::mem_pestat] low and high boundaries for proper pairs: (1, 11265) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (175, 275, 718) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1804) [M::mem_pestat] mean and std.dev: (327.19, 248.34) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2347) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 700360 sequences (100000048 bp) in 1.846 CPU sec, 1.850 real sec... [M::mem_process_seqs] Processed 700294 reads in 185.947 CPU sec, 6.134 real sec [M::mem_process_seqs] Processed 700614 reads in 130.043 CPU sec, 4.180 real sec sorting block 25, #reads = 1070060 mem = 536883218 peak = 1065345024 [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 279860, 26, 51) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (206, 311, 2632) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7484) [M::mem_pestat] mean and std.dev: (1327.07, 1589.21) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9910) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (159, 235, 339) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 699) [M::mem_pestat] mean and std.dev: (258.90, 127.56) [M::mem_pestat] low and high boundaries for proper pairs: (1, 879) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (363, 1158, 3944) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 11106) [M::mem_pestat] mean and std.dev: (2129.15, 2204.38) [M::mem_pestat] low and high boundaries for proper pairs: (1, 14687) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (207, 353, 1075) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2811) [M::mem_pestat] mean and std.dev: (662.86, 654.07) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3679) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 699532 sequences (100000200 bp) in 2.465 CPU sec, 2.698 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 279957, 32, 47) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (163, 283, 1388) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3838) [M::mem_pestat] mean and std.dev: (615.48, 680.49) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5063) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (159, 236, 340) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 702) [M::mem_pestat] mean and std.dev: (259.31, 127.75) [M::mem_pestat] low and high boundaries for proper pairs: (1, 883) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (763, 1533, 2069) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4681) [M::mem_pestat] mean and std.dev: (1405.67, 879.19) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5987) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (185, 350, 867) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2231) [M::mem_pestat] mean and std.dev: (529.88, 443.91) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2913) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 699492 sequences (100000052 bp) in 1.674 CPU sec, 1.715 real sec... [M::mem_process_seqs] Processed 700400 reads in 184.349 CPU sec, 5.938 real sec [M::mem_process_seqs] Processed 700360 reads in 130.192 CPU sec, 4.250 real sec sorting block 26, #reads = 1069084 mem = 536878733 peak = 1065345024 [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 279884, 22, 55) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (187, 372, 915) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2371) [M::mem_pestat] mean and std.dev: (478.95, 367.30) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3099) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (161, 238, 342) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 704) [M::mem_pestat] mean and std.dev: (261.10, 128.25) [M::mem_pestat] low and high boundaries for proper pairs: (1, 885) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (269, 721, 1474) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3884) [M::mem_pestat] mean and std.dev: (827.16, 795.78) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5089) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (287, 491, 1418) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3680) [M::mem_pestat] mean and std.dev: (662.18, 570.12) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4811) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 699508 sequences (100000016 bp) in 2.319 CPU sec, 2.603 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 279486, 39, 61) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (191, 503, 968) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2522) [M::mem_pestat] mean and std.dev: (563.58, 553.50) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3299) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (160, 237, 341) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 703) [M::mem_pestat] mean and std.dev: (260.84, 128.41) [M::mem_pestat] low and high boundaries for proper pairs: (1, 884) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (521, 840, 1358) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3032) [M::mem_pestat] mean and std.dev: (768.83, 506.81) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3869) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (236, 393, 726) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1706) [M::mem_pestat] mean and std.dev: (503.53, 377.39) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2196) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 699160 sequences (100000281 bp) in 1.925 CPU sec, 2.025 real sec... [M::mem_process_seqs] Processed 699532 reads in 188.349 CPU sec, 6.134 real sec sorting block 27, #reads = 1067904 mem = 536879106 peak = 1065345024 [M::mem_process_seqs] Processed 699492 reads in 130.195 CPU sec, 4.209 real sec [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 279411, 28, 58) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (184, 318, 498) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1126) [M::mem_pestat] mean and std.dev: (268.11, 112.33) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1440) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (161, 239, 343) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 707) [M::mem_pestat] mean and std.dev: (261.75, 128.83) [M::mem_pestat] low and high boundaries for proper pairs: (1, 889) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (694, 994, 1373) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2731) [M::mem_pestat] mean and std.dev: (903.28, 399.24) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3410) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (218, 393, 1414) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3806) [M::mem_pestat] mean and std.dev: (790.85, 906.93) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5002) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 699228 sequences (100000211 bp) in 2.430 CPU sec, 2.792 real sec... sorting block 28, #reads = 1067159 mem = 536880513 peak = 1083846656 [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 279846, 39, 50) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (164, 376, 1456) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4040) [M::mem_pestat] mean and std.dev: (808.29, 871.30) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5332) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (161, 239, 346) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 716) [M::mem_pestat] mean and std.dev: (263.86, 130.76) [M::mem_pestat] low and high boundaries for proper pairs: (1, 901) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (531, 1240, 1894) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4620) [M::mem_pestat] mean and std.dev: (1414.31, 1220.11) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6295) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (185, 250, 895) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2315) [M::mem_pestat] mean and std.dev: (491.88, 594.82) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3025) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 698702 sequences (100000264 bp) in 1.664 CPU sec, 2.011 real sec... [M::mem_process_seqs] Processed 699508 reads in 188.403 CPU sec, 6.169 real sec [M::mem_process_seqs] Processed 699160 reads in 127.078 CPU sec, 4.216 real sec sorting block 29, #reads = 1067247 mem = 536878190 peak = 1083846656 [M::process] read 698880 sequences (100000253 bp) in 2.279 CPU sec, 2.693 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 280112, 25, 50) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (195, 339, 578) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1344) [M::mem_pestat] mean and std.dev: (400.52, 254.65) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1727) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (162, 241, 347) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 717) [M::mem_pestat] mean and std.dev: (264.48, 130.50) [M::mem_pestat] low and high boundaries for proper pairs: (1, 902) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (274, 603, 2408) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6676) [M::mem_pestat] mean and std.dev: (1343.80, 1429.02) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8810) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (154, 328, 550) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1342) [M::mem_pestat] mean and std.dev: (324.05, 230.88) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1738) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 699518 sequences (100000052 bp) in 1.829 CPU sec, 1.864 real sec... [M::mem_process_seqs] Processed 698702 reads in 107.961 CPU sec, 3.473 real sec sorting block 30, #reads = 1067845 mem = 536889920 peak = 1083846656 [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 279330, 22, 59) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (252, 528, 1863) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5085) [M::mem_pestat] mean and std.dev: (1090.25, 1036.29) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6696) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (161, 240, 346) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 716) [M::mem_pestat] mean and std.dev: (263.55, 130.11) [M::mem_pestat] low and high boundaries for proper pairs: (1, 901) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (160, 860, 1962) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5566) [M::mem_pestat] mean and std.dev: (986.38, 1101.00) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7368) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (205, 484, 1418) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3844) [M::mem_pestat] mean and std.dev: (737.83, 733.38) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5057) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 279526, 26, 58) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (223, 461, 1644) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4486) [M::mem_pestat] mean and std.dev: (1111.44, 1225.52) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6014) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (162, 241, 348) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 720) [M::mem_pestat] mean and std.dev: (264.65, 131.21) [M::mem_pestat] low and high boundaries for proper pairs: (1, 906) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (266, 594, 1802) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4874) [M::mem_pestat] mean and std.dev: (1094.48, 1145.67) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6410) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (186, 369, 954) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2490) [M::mem_pestat] mean and std.dev: (549.64, 487.59) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3258) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 699228 reads in 289.118 CPU sec, 9.456 real sec [M::process] read 702648 sequences (100000130 bp) in 1.803 CPU sec, 1.958 real sec... [M::mem_process_seqs] Processed 698880 reads in 161.567 CPU sec, 5.254 real sec sorting block 31, #reads = 1067412 mem = 536880286 peak = 1083846656 [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 280205, 16, 38) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (195, 373, 748) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1854) [M::mem_pestat] mean and std.dev: (472.37, 373.77) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2407) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (161, 240, 348) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 722) [M::mem_pestat] mean and std.dev: (264.56, 132.32) [M::mem_pestat] low and high boundaries for proper pairs: (1, 909) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (775, 1734, 2581) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6193) [M::mem_pestat] mean and std.dev: (1650.27, 1197.41) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7999) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (255, 346, 1226) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3168) [M::mem_pestat] mean and std.dev: (640.97, 532.01) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4139) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 705984 sequences (100000299 bp) in 2.524 CPU sec, 2.836 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 280982, 22, 52) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (251, 362, 1691) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4571) [M::mem_pestat] mean and std.dev: (858.32, 973.91) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6011) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (156, 232, 339) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 705) [M::mem_pestat] mean and std.dev: (257.48, 129.17) [M::mem_pestat] low and high boundaries for proper pairs: (1, 888) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (327, 1180, 2638) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7260) [M::mem_pestat] mean and std.dev: (1876.91, 1911.81) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9571) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (163, 460, 526) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1252) [M::mem_pestat] mean and std.dev: (341.40, 200.90) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1615) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 705496 sequences (100000257 bp) in 1.630 CPU sec, 1.721 real sec... [M::mem_process_seqs] Processed 699518 reads in 187.664 CPU sec, 6.053 real sec [M::mem_process_seqs] Processed 702648 reads in 130.872 CPU sec, 4.203 real sec sorting block 32, #reads = 1068337 mem = 536881310 peak = 1083846656 [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 282212, 21, 47) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (326, 544, 1800) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4748) [M::mem_pestat] mean and std.dev: (1064.00, 1085.03) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6222) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (152, 225, 327) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 677) [M::mem_pestat] mean and std.dev: (249.17, 124.31) [M::mem_pestat] low and high boundaries for proper pairs: (1, 852) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (803, 1816, 2203) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5003) [M::mem_pestat] mean and std.dev: (1441.79, 753.22) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6403) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (245, 426, 1715) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4655) [M::mem_pestat] mean and std.dev: (951.65, 985.41) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6125) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 705190 sequences (100000003 bp) in 2.348 CPU sec, 2.742 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 281698, 31, 55) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (168, 347, 658) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1638) [M::mem_pestat] mean and std.dev: (372.45, 326.44) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2128) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (152, 226, 327) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 677) [M::mem_pestat] mean and std.dev: (249.77, 124.25) [M::mem_pestat] low and high boundaries for proper pairs: (1, 852) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (400, 562, 2064) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5392) [M::mem_pestat] mean and std.dev: (1079.48, 931.63) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7056) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (197, 431, 1023) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2675) [M::mem_pestat] mean and std.dev: (551.92, 456.47) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3501) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 703776 sequences (100000092 bp) in 1.745 CPU sec, 1.773 real sec... [M::mem_process_seqs] Processed 705984 reads in 184.318 CPU sec, 5.951 real sec sorting block 33, #reads = 1071593 mem = 536878604 peak = 1083846656 [M::mem_process_seqs] Processed 705496 reads in 127.483 CPU sec, 4.087 real sec [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 282067, 22, 48) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (212, 475, 1461) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3959) [M::mem_pestat] mean and std.dev: (763.74, 820.29) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5208) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (152, 226, 328) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 680) [M::mem_pestat] mean and std.dev: (250.38, 124.61) [M::mem_pestat] low and high boundaries for proper pairs: (1, 856) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (326, 543, 989) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2315) [M::mem_pestat] mean and std.dev: (668.10, 523.36) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2978) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (165, 272, 515) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1215) [M::mem_pestat] mean and std.dev: (254.35, 124.74) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1565) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR sorting block 34, #reads = 1071601 mem = 536879431 peak = 1083846656 [M::process] read 702998 sequences (100000184 bp) in 2.759 CPU sec, 3.412 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 281278, 37, 49) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (172, 393, 617) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1507) [M::mem_pestat] mean and std.dev: (376.11, 259.01) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1952) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (155, 230, 333) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 689) [M::mem_pestat] mean and std.dev: (253.76, 125.78) [M::mem_pestat] low and high boundaries for proper pairs: (1, 867) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (322, 482, 1637) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4267) [M::mem_pestat] mean and std.dev: (961.51, 921.93) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5582) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (190, 346, 1111) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2953) [M::mem_pestat] mean and std.dev: (636.91, 766.49) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3874) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 702288 sequences (100000169 bp) in 1.735 CPU sec, 1.751 real sec... [M::mem_process_seqs] Processed 705190 reads in 184.753 CPU sec, 6.050 real sec [M::mem_process_seqs] Processed 703776 reads in 129.444 CPU sec, 4.289 real sec sorting block 35, #reads = 1072805 mem = 536880388 peak = 1083846656 [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 281304, 17, 54) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (142, 257, 786) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2074) [M::mem_pestat] mean and std.dev: (361.10, 350.39) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2718) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (156, 231, 335) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 693) [M::mem_pestat] mean and std.dev: (255.36, 126.63) [M::mem_pestat] low and high boundaries for proper pairs: (1, 872) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (804, 1217, 2589) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6159) [M::mem_pestat] mean and std.dev: (1370.29, 909.49) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7944) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (175, 405, 976) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2578) [M::mem_pestat] mean and std.dev: (495.76, 476.41) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3379) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 701530 sequences (100000186 bp) in 2.417 CPU sec, 2.682 real sec... [M::process] read 701434 sequences (100000029 bp) in 1.827 CPU sec, 1.867 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 281119, 21, 34) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (217, 278, 953) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2425) [M::mem_pestat] mean and std.dev: (439.39, 347.32) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3161) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (157, 233, 338) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 700) [M::mem_pestat] mean and std.dev: (257.14, 127.44) [M::mem_pestat] low and high boundaries for proper pairs: (1, 881) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (114, 892, 1318) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3726) [M::mem_pestat] mean and std.dev: (780.84, 800.62) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4930) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (190, 402, 1315) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3565) [M::mem_pestat] mean and std.dev: (717.87, 935.36) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4690) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 702998 reads in 186.197 CPU sec, 6.072 real sec [M::mem_process_seqs] Processed 702288 reads in 127.466 CPU sec, 4.122 real sec sorting block 36, #reads = 1070590 mem = 536877563 peak = 1083846656 [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 280468, 42, 55) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (157, 404, 1082) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2932) [M::mem_pestat] mean and std.dev: (591.98, 616.60) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3857) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (158, 234, 339) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 701) [M::mem_pestat] mean and std.dev: (258.21, 127.52) [M::mem_pestat] low and high boundaries for proper pairs: (1, 882) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (238, 696, 1538) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4138) [M::mem_pestat] mean and std.dev: (935.88, 921.64) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5438) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (221, 325, 2061) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5741) [M::mem_pestat] mean and std.dev: (824.56, 1133.81) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7581) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 701106 sequences (100000206 bp) in 2.495 CPU sec, 2.770 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 280611, 33, 39) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (194, 444, 1329) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3599) [M::mem_pestat] mean and std.dev: (812.11, 704.36) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4734) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (158, 235, 340) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 704) [M::mem_pestat] mean and std.dev: (259.28, 128.21) [M::mem_pestat] low and high boundaries for proper pairs: (1, 886) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (552, 831, 2445) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6231) [M::mem_pestat] mean and std.dev: (1266.10, 1112.04) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8124) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (297, 488, 1286) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3264) [M::mem_pestat] mean and std.dev: (757.86, 674.92) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4253) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 701222 sequences (100000247 bp) in 1.700 CPU sec, 1.708 real sec... [M::mem_process_seqs] Processed 701530 reads in 185.497 CPU sec, 6.006 real sec sorting block 37, #reads = 1071143 mem = 536877984 peak = 1083846656 [M::mem_process_seqs] Processed 701434 reads in 127.597 CPU sec, 4.190 real sec [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 280138, 25, 48) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (263, 458, 1296) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3362) [M::mem_pestat] mean and std.dev: (761.45, 726.73) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4395) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (158, 236, 343) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 713) [M::mem_pestat] mean and std.dev: (260.45, 129.21) [M::mem_pestat] low and high boundaries for proper pairs: (1, 898) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (204, 483, 2295) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6477) [M::mem_pestat] mean and std.dev: (1350.44, 1632.80) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8568) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (246, 382, 891) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2181) [M::mem_pestat] mean and std.dev: (632.38, 558.46) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2866) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 700562 sequences (100000292 bp) in 2.129 CPU sec, 2.320 real sec... [M::process] read 700514 sequences (100000026 bp) in 1.708 CPU sec, 1.745 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 280605, 19, 60) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (154, 304, 938) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2506) [M::mem_pestat] mean and std.dev: (494.88, 469.73) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3290) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (158, 237, 342) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 710) [M::mem_pestat] mean and std.dev: (260.39, 129.21) [M::mem_pestat] low and high boundaries for proper pairs: (1, 894) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (715, 1966, 2411) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5803) [M::mem_pestat] mean and std.dev: (1514.42, 907.46) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7499) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (216, 559, 1778) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4902) [M::mem_pestat] mean and std.dev: (792.73, 859.35) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6464) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 701106 reads in 186.673 CPU sec, 6.110 real sec sorting block 38, #reads = 1070235 mem = 536878954 peak = 1083846656 [M::mem_process_seqs] Processed 701222 reads in 126.516 CPU sec, 4.111 real sec sorting block 39, #reads = 1069759 mem = 536879766 peak = 1145278464 [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 280581, 31, 44) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (226, 310, 797) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1939) [M::mem_pestat] mean and std.dev: (387.10, 255.69) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2510) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (159, 237, 343) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 711) [M::mem_pestat] mean and std.dev: (261.15, 129.43) [M::mem_pestat] low and high boundaries for proper pairs: (1, 895) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (549, 1106, 2317) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5853) [M::mem_pestat] mean and std.dev: (1397.16, 1206.13) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7621) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (156, 452, 856) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2256) [M::mem_pestat] mean and std.dev: (543.52, 491.16) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2956) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 700910 sequences (100000278 bp) in 2.436 CPU sec, 2.857 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 279959, 29, 46) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (204, 334, 1197) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3183) [M::mem_pestat] mean and std.dev: (609.02, 571.94) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4176) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (159, 237, 344) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 714) [M::mem_pestat] mean and std.dev: (261.75, 129.95) [M::mem_pestat] low and high boundaries for proper pairs: (1, 899) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (575, 1032, 2406) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6068) [M::mem_pestat] mean and std.dev: (1482.85, 1401.80) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7899) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (222, 266, 600) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1356) [M::mem_pestat] mean and std.dev: (317.54, 218.42) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1734) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 700428 sequences (100000137 bp) in 1.646 CPU sec, 1.654 real sec... [M::mem_process_seqs] Processed 700562 reads in 186.753 CPU sec, 6.129 real sec [M::mem_process_seqs] Processed 700514 reads in 128.032 CPU sec, 4.211 real sec sorting block 40, #reads = 1070555 mem = 536880719 peak = 1145278464 [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 280270, 26, 47) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (220, 287, 661) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1543) [M::mem_pestat] mean and std.dev: (441.47, 350.89) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1984) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (158, 235, 338) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 698) [M::mem_pestat] mean and std.dev: (258.24, 127.38) [M::mem_pestat] low and high boundaries for proper pairs: (1, 878) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (247, 437, 878) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2140) [M::mem_pestat] mean and std.dev: (563.54, 502.55) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2771) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (156, 322, 2289) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6555) [M::mem_pestat] mean and std.dev: (1324.47, 1837.12) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8688) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 700586 sequences (100000116 bp) in 2.408 CPU sec, 2.958 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 279969, 33, 53) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (164, 307, 903) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2381) [M::mem_pestat] mean and std.dev: (424.09, 383.40) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3120) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (160, 237, 341) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 703) [M::mem_pestat] mean and std.dev: (260.43, 128.75) [M::mem_pestat] low and high boundaries for proper pairs: (1, 884) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (475, 819, 1164) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2542) [M::mem_pestat] mean and std.dev: (721.54, 329.33) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3231) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (171, 429, 1409) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3885) [M::mem_pestat] mean and std.dev: (668.61, 708.76) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5123) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 700230 sequences (100000281 bp) in 1.689 CPU sec, 1.706 real sec... [M::mem_process_seqs] Processed 700910 reads in 187.474 CPU sec, 6.137 real sec [M::mem_process_seqs] Processed 700428 reads in 127.606 CPU sec, 4.095 real sec sorting block 41, #reads = 1069736 mem = 536880447 peak = 1145278464 [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 279931, 15, 48) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (214, 651, 2114) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5914) [M::mem_pestat] mean and std.dev: (1058.83, 967.83) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7814) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (159, 236, 339) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 699) [M::mem_pestat] mean and std.dev: (259.09, 127.39) [M::mem_pestat] low and high boundaries for proper pairs: (1, 879) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (1000, 1634, 5285) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13855) [M::mem_pestat] mean and std.dev: (2719.53, 2655.56) [M::mem_pestat] low and high boundaries for proper pairs: (1, 18140) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (231, 357, 627) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1419) [M::mem_pestat] mean and std.dev: (449.41, 342.26) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1818) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 700046 sequences (100000258 bp) in 2.509 CPU sec, 2.861 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 279928, 26, 55) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (346, 823, 1698) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4402) [M::mem_pestat] mean and std.dev: (825.44, 776.35) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5754) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (159, 236, 340) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 702) [M::mem_pestat] mean and std.dev: (259.57, 127.54) [M::mem_pestat] low and high boundaries for proper pairs: (1, 883) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (426, 836, 1223) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2817) [M::mem_pestat] mean and std.dev: (970.71, 762.13) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4019) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (217, 489, 1129) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2953) [M::mem_pestat] mean and std.dev: (573.30, 507.00) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3865) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 700142 sequences (100000081 bp) in 1.706 CPU sec, 1.726 real sec... [M::mem_process_seqs] Processed 700586 reads in 189.518 CPU sec, 6.203 real sec sorting block 42, #reads = 1070022 mem = 536879615 peak = 1145278464 [M::mem_process_seqs] Processed 700230 reads in 132.954 CPU sec, 4.254 real sec sorting block 43, #reads = 1068314 mem = 536877879 peak = 1147269120 [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 280187, 23, 52) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (225, 465, 873) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2169) [M::mem_pestat] mean and std.dev: (539.37, 427.73) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2817) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (160, 238, 342) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 706) [M::mem_pestat] mean and std.dev: (261.27, 128.88) [M::mem_pestat] low and high boundaries for proper pairs: (1, 888) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (246, 513, 1245) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3243) [M::mem_pestat] mean and std.dev: (735.73, 649.44) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4242) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (186, 294, 707) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1749) [M::mem_pestat] mean and std.dev: (439.96, 438.76) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2270) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 699578 sequences (100000207 bp) in 2.277 CPU sec, 2.510 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 279984, 25, 37) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (161, 279, 930) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2468) [M::mem_pestat] mean and std.dev: (459.18, 388.42) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3237) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (160, 237, 341) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 703) [M::mem_pestat] mean and std.dev: (260.38, 128.09) [M::mem_pestat] low and high boundaries for proper pairs: (1, 884) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (635, 1043, 2806) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7148) [M::mem_pestat] mean and std.dev: (1396.68, 973.92) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9319) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (216, 420, 1072) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2784) [M::mem_pestat] mean and std.dev: (555.88, 498.24) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3640) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 699516 sequences (100000166 bp) in 1.720 CPU sec, 1.815 real sec... [M::mem_process_seqs] Processed 700046 reads in 185.126 CPU sec, 5.976 real sec [M::mem_process_seqs] Processed 700142 reads in 137.518 CPU sec, 4.441 real sec sorting block 44, #reads = 1069012 mem = 536878175 peak = 1147269120 [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 279254, 49, 52) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (182, 407, 1329) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3623) [M::mem_pestat] mean and std.dev: (730.55, 906.24) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4770) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (161, 238, 342) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 704) [M::mem_pestat] mean and std.dev: (261.30, 127.92) [M::mem_pestat] low and high boundaries for proper pairs: (1, 885) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (212, 476, 1610) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4406) [M::mem_pestat] mean and std.dev: (680.33, 712.54) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5804) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (211, 353, 816) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2026) [M::mem_pestat] mean and std.dev: (518.42, 461.37) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2631) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 699968 sequences (100000003 bp) in 2.317 CPU sec, 2.768 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 279534, 26, 42) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (164, 371, 695) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1757) [M::mem_pestat] mean and std.dev: (405.18, 300.99) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2288) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (161, 239, 344) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 710) [M::mem_pestat] mean and std.dev: (262.25, 129.35) [M::mem_pestat] low and high boundaries for proper pairs: (1, 893) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (744, 1300, 1376) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2640) [M::mem_pestat] mean and std.dev: (996.55, 567.52) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3272) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (200, 297, 859) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2177) [M::mem_pestat] mean and std.dev: (442.46, 484.38) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2836) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 699572 sequences (100000061 bp) in 1.698 CPU sec, 1.728 real sec... [M::mem_process_seqs] Processed 699578 reads in 185.761 CPU sec, 6.057 real sec [M::mem_process_seqs] Processed 699516 reads in 131.710 CPU sec, 4.283 real sec sorting block 45, #reads = 1068115 mem = 536882591 peak = 1147269120 [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 280407, 25, 64) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (151, 381, 1410) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3928) [M::mem_pestat] mean and std.dev: (735.93, 845.59) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5187) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (160, 238, 344) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 712) [M::mem_pestat] mean and std.dev: (262.28, 130.11) [M::mem_pestat] low and high boundaries for proper pairs: (1, 896) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (515, 1416, 2366) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6068) [M::mem_pestat] mean and std.dev: (1386.40, 854.06) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7919) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (205, 349, 1211) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3223) [M::mem_pestat] mean and std.dev: (719.54, 795.45) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4229) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 699698 sequences (100000050 bp) in 2.355 CPU sec, 2.826 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 279720, 28, 46) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (219, 808, 1618) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4416) [M::mem_pestat] mean and std.dev: (932.14, 866.73) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5815) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (161, 239, 346) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 716) [M::mem_pestat] mean and std.dev: (263.46, 130.87) [M::mem_pestat] low and high boundaries for proper pairs: (1, 901) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (584, 1219, 2076) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5060) [M::mem_pestat] mean and std.dev: (1227.69, 902.60) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6552) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (187, 374, 1150) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3076) [M::mem_pestat] mean and std.dev: (647.66, 728.77) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4039) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 699906 sequences (100000093 bp) in 1.681 CPU sec, 1.842 real sec... [M::mem_process_seqs] Processed 699968 reads in 188.939 CPU sec, 6.114 real sec sorting block 46, #reads = 1067134 mem = 536880669 peak = 1147269120 [M::mem_process_seqs] Processed 699572 reads in 130.750 CPU sec, 4.279 real sec sorting block 47, #reads = 1067618 mem = 536878783 peak = 1147269120 [M::process] read 703424 sequences (100000293 bp) in 2.525 CPU sec, 2.723 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 280145, 26, 42) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (176, 426, 692) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1724) [M::mem_pestat] mean and std.dev: (492.31, 391.53) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2240) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (160, 238, 342) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 706) [M::mem_pestat] mean and std.dev: (261.44, 129.75) [M::mem_pestat] low and high boundaries for proper pairs: (1, 888) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (347, 588, 1300) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3206) [M::mem_pestat] mean and std.dev: (767.26, 680.91) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4159) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (195, 323, 1048) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2754) [M::mem_pestat] mean and std.dev: (672.78, 755.42) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3694) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 704588 sequences (100000190 bp) in 1.805 CPU sec, 1.822 real sec... [M::mem_process_seqs] Processed 699906 reads in 113.970 CPU sec, 3.661 real sec [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 279778, 29, 46) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (219, 436, 1525) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4137) [M::mem_pestat] mean and std.dev: (839.05, 1044.17) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5443) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (160, 238, 344) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 712) [M::mem_pestat] mean and std.dev: (262.28, 130.21) [M::mem_pestat] low and high boundaries for proper pairs: (1, 896) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (185, 1215, 2273) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6449) [M::mem_pestat] mean and std.dev: (1325.69, 1287.90) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8537) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (221, 379, 992) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2534) [M::mem_pestat] mean and std.dev: (611.16, 541.39) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3305) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 280739, 21, 57) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (188, 306, 1333) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3623) [M::mem_pestat] mean and std.dev: (694.95, 781.92) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4768) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (155, 230, 334) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 692) [M::mem_pestat] mean and std.dev: (254.54, 126.66) [M::mem_pestat] low and high boundaries for proper pairs: (1, 871) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (76, 241, 957) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2719) [M::mem_pestat] mean and std.dev: (458.05, 458.45) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3600) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (225, 341, 838) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2064) [M::mem_pestat] mean and std.dev: (474.62, 419.43) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2677) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 704676 sequences (100000212 bp) in 1.821 CPU sec, 1.842 real sec... [M::mem_process_seqs] Processed 699698 reads in 299.421 CPU sec, 9.728 real sec sorting block 48, #reads = 1066698 mem = 536878244 peak = 1147269120 [M::mem_process_seqs] Processed 703424 reads in 160.162 CPU sec, 5.192 real sec [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 281496, 17, 31) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (328, 866, 1516) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3892) [M::mem_pestat] mean and std.dev: (821.06, 646.09) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5080) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (153, 227, 329) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 681) [M::mem_pestat] mean and std.dev: (251.13, 124.79) [M::mem_pestat] low and high boundaries for proper pairs: (1, 857) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (271, 659, 1839) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4975) [M::mem_pestat] mean and std.dev: (963.29, 825.14) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6543) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (289, 417, 1484) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3874) [M::mem_pestat] mean and std.dev: (841.70, 764.23) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5069) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR sorting block 49, #reads = 1067039 mem = 536880386 peak = 1163632640 [M::process] read 703768 sequences (100000182 bp) in 2.495 CPU sec, 2.889 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 281947, 28, 50) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (186, 306, 614) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1470) [M::mem_pestat] mean and std.dev: (327.43, 225.94) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1898) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (153, 227, 331) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 687) [M::mem_pestat] mean and std.dev: (251.94, 125.60) [M::mem_pestat] low and high boundaries for proper pairs: (1, 865) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (457, 642, 1211) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2719) [M::mem_pestat] mean and std.dev: (828.42, 697.35) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3618) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (151, 259, 483) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1147) [M::mem_pestat] mean and std.dev: (255.86, 130.94) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1479) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 703522 sequences (100000258 bp) in 1.845 CPU sec, 1.895 real sec... [M::mem_process_seqs] Processed 704588 reads in 181.182 CPU sec, 5.859 real sec [M::mem_process_seqs] Processed 704676 reads in 127.771 CPU sec, 4.351 real sec sorting block 50, #reads = 1071907 mem = 536892980 peak = 1163632640 [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 281576, 31, 74) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (190, 251, 1222) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3286) [M::mem_pestat] mean and std.dev: (578.50, 705.47) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4318) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (154, 229, 332) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 688) [M::mem_pestat] mean and std.dev: (253.25, 126.03) [M::mem_pestat] low and high boundaries for proper pairs: (1, 866) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (148, 546, 751) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1957) [M::mem_pestat] mean and std.dev: (447.41, 292.51) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2560) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (405, 733, 1462) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3576) [M::mem_pestat] mean and std.dev: (900.82, 736.80) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4633) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 703188 sequences (100000088 bp) in 2.254 CPU sec, 2.787 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 281318, 14, 42) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (145, 269, 1003) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2719) [M::mem_pestat] mean and std.dev: (532.00, 492.46) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3577) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (155, 231, 335) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 695) [M::mem_pestat] mean and std.dev: (254.92, 126.83) [M::mem_pestat] low and high boundaries for proper pairs: (1, 875) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (405, 1032, 1032) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2286) [M::mem_pestat] mean and std.dev: (793.00, 497.98) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2913) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (190, 474, 746) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1858) [M::mem_pestat] mean and std.dev: (468.43, 375.45) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2414) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 702384 sequences (100000146 bp) in 1.734 CPU sec, 1.770 real sec... [M::mem_process_seqs] Processed 703768 reads in 184.475 CPU sec, 6.220 real sec [M::mem_process_seqs] Processed 703522 reads in 129.216 CPU sec, 4.177 real sec sorting block 51, #reads = 1072514 mem = 536878226 peak = 1163632640 [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 281487, 11, 31) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (256, 609, 1484) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3940) [M::mem_pestat] mean and std.dev: (750.06, 648.91) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5168) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (155, 231, 335) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 695) [M::mem_pestat] mean and std.dev: (255.03, 126.84) [M::mem_pestat] low and high boundaries for proper pairs: (1, 875) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (1413, 1427, 4071) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9387) [M::mem_pestat] mean and std.dev: (2542.82, 2249.36) [M::mem_pestat] low and high boundaries for proper pairs: (1, 12045) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (279, 931, 1438) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3756) [M::mem_pestat] mean and std.dev: (1043.39, 751.05) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4915) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 701954 sequences (100000066 bp) in 2.341 CPU sec, 2.656 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 280537, 23, 54) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (181, 294, 972) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2554) [M::mem_pestat] mean and std.dev: (544.18, 582.26) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3345) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (156, 233, 339) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 705) [M::mem_pestat] mean and std.dev: (257.75, 128.46) [M::mem_pestat] low and high boundaries for proper pairs: (1, 888) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (345, 804, 1068) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2514) [M::mem_pestat] mean and std.dev: (646.95, 398.13) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3237) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (187, 326, 1038) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2740) [M::mem_pestat] mean and std.dev: (593.77, 709.24) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3591) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 701396 sequences (100000000 bp) in 1.724 CPU sec, 1.731 real sec... [M::mem_process_seqs] Processed 703188 reads in 182.672 CPU sec, 5.893 real sec sorting block 52, #reads = 1072437 mem = 536880471 peak = 1163632640 [M::mem_process_seqs] Processed 702384 reads in 135.500 CPU sec, 4.365 real sec [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 280536, 28, 40) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (374, 515, 1327) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3233) [M::mem_pestat] mean and std.dev: (623.23, 480.26) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4186) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (157, 234, 340) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 706) [M::mem_pestat] mean and std.dev: (258.85, 129.33) [M::mem_pestat] low and high boundaries for proper pairs: (1, 889) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (406, 851, 1385) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3343) [M::mem_pestat] mean and std.dev: (975.48, 817.40) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4322) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (220, 267, 754) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1822) [M::mem_pestat] mean and std.dev: (436.25, 418.37) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2356) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR sorting block 53, #reads = 1072159 mem = 536882570 peak = 1163632640 [M::process] read 701288 sequences (100000124 bp) in 2.215 CPU sec, 2.962 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 280518, 23, 49) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (186, 537, 1261) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3411) [M::mem_pestat] mean and std.dev: (687.13, 586.55) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4486) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (158, 236, 342) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 710) [M::mem_pestat] mean and std.dev: (260.17, 129.36) [M::mem_pestat] low and high boundaries for proper pairs: (1, 894) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (833, 1878, 3192) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7910) [M::mem_pestat] mean and std.dev: (2282.95, 1904.85) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10269) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (222, 458, 856) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2124) [M::mem_pestat] mean and std.dev: (506.00, 334.24) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2758) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 701112 sequences (100000272 bp) in 1.692 CPU sec, 1.721 real sec... [M::mem_process_seqs] Processed 701954 reads in 180.441 CPU sec, 5.847 real sec [M::mem_process_seqs] Processed 701396 reads in 126.652 CPU sec, 4.328 real sec sorting block 54, #reads = 1070820 mem = 536877988 peak = 1163632640 [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 280356, 20, 54) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (185, 432, 1049) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2777) [M::mem_pestat] mean and std.dev: (643.93, 613.93) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3641) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (158, 236, 342) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 710) [M::mem_pestat] mean and std.dev: (260.29, 129.51) [M::mem_pestat] low and high boundaries for proper pairs: (1, 894) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (77, 369, 1211) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3479) [M::mem_pestat] mean and std.dev: (631.63, 746.47) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4613) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (204, 488, 1610) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4422) [M::mem_pestat] mean and std.dev: (890.39, 937.13) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5828) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 701212 sequences (100000215 bp) in 2.337 CPU sec, 2.876 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 280516, 21, 54) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (205, 356, 471) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1003) [M::mem_pestat] mean and std.dev: (325.94, 169.39) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1269) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (159, 237, 343) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 711) [M::mem_pestat] mean and std.dev: (261.09, 129.79) [M::mem_pestat] low and high boundaries for proper pairs: (1, 895) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (652, 918, 3371) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8809) [M::mem_pestat] mean and std.dev: (1465.60, 1513.10) [M::mem_pestat] low and high boundaries for proper pairs: (1, 11528) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (239, 358, 929) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2309) [M::mem_pestat] mean and std.dev: (620.38, 517.17) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2999) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 701576 sequences (100000266 bp) in 1.883 CPU sec, 1.912 real sec... [M::mem_process_seqs] Processed 701288 reads in 186.479 CPU sec, 6.273 real sec [M::mem_process_seqs] Processed 701112 reads in 126.979 CPU sec, 4.076 real sec sorting block 55, #reads = 1069922 mem = 536879746 peak = 1163632640 [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 279973, 28, 53) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (171, 352, 901) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2361) [M::mem_pestat] mean and std.dev: (509.50, 470.52) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3091) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (158, 236, 341) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 707) [M::mem_pestat] mean and std.dev: (260.20, 129.36) [M::mem_pestat] low and high boundaries for proper pairs: (1, 890) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (102, 295, 1835) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5301) [M::mem_pestat] mean and std.dev: (951.93, 1186.19) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7034) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (249, 428, 1081) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2745) [M::mem_pestat] mean and std.dev: (633.82, 591.53) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3577) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 703256 sequences (100000052 bp) in 2.372 CPU sec, 2.788 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 279878, 24, 58) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (327, 859, 1368) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3450) [M::mem_pestat] mean and std.dev: (848.77, 611.46) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4491) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (157, 235, 341) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 709) [M::mem_pestat] mean and std.dev: (259.51, 129.55) [M::mem_pestat] low and high boundaries for proper pairs: (1, 893) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (125, 184, 1408) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3974) [M::mem_pestat] mean and std.dev: (702.54, 798.13) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5257) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (256, 431, 1138) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2902) [M::mem_pestat] mean and std.dev: (605.00, 513.69) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3784) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 701100 sequences (100000121 bp) in 1.718 CPU sec, 1.814 real sec... [M::mem_process_seqs] Processed 701212 reads in 185.073 CPU sec, 5.999 real sec sorting block 56, #reads = 1070032 mem = 536879157 peak = 1163632640 [M::mem_process_seqs] Processed 701576 reads in 129.250 CPU sec, 4.402 real sec sorting block 57, #reads = 1070026 mem = 536882035 peak = 1163632640 [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 280499, 28, 36) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (161, 288, 784) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2030) [M::mem_pestat] mean and std.dev: (451.70, 401.37) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2653) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (155, 228, 328) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 674) [M::mem_pestat] mean and std.dev: (251.25, 123.77) [M::mem_pestat] low and high boundaries for proper pairs: (1, 847) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (591, 1541, 2422) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6084) [M::mem_pestat] mean and std.dev: (1463.29, 940.28) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7915) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (231, 390, 881) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2181) [M::mem_pestat] mean and std.dev: (538.33, 387.45) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2831) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 700994 sequences (100000051 bp) in 2.496 CPU sec, 2.746 real sec... [M::process] read 700240 sequences (100000152 bp) in 1.877 CPU sec, 1.915 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 279832, 20, 56) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (230, 411, 1233) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3239) [M::mem_pestat] mean and std.dev: (690.24, 623.70) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4242) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (158, 234, 337) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 695) [M::mem_pestat] mean and std.dev: (257.52, 126.95) [M::mem_pestat] low and high boundaries for proper pairs: (1, 874) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (218, 688, 1412) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3800) [M::mem_pestat] mean and std.dev: (742.72, 708.73) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4994) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (161, 353, 926) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2456) [M::mem_pestat] mean and std.dev: (485.83, 444.70) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3221) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 703256 reads in 191.910 CPU sec, 6.419 real sec [M::mem_process_seqs] Processed 701100 reads in 131.052 CPU sec, 4.239 real sec sorting block 58, #reads = 1069628 mem = 536877759 peak = 1163632640 [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 280012, 34, 46) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (191, 479, 1134) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3020) [M::mem_pestat] mean and std.dev: (757.15, 657.84) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3963) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (158, 234, 337) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 695) [M::mem_pestat] mean and std.dev: (257.60, 126.65) [M::mem_pestat] low and high boundaries for proper pairs: (1, 874) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (330, 830, 2082) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5586) [M::mem_pestat] mean and std.dev: (1344.79, 1273.07) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7338) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (189, 400, 931) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2415) [M::mem_pestat] mean and std.dev: (501.18, 460.98) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3157) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 700384 sequences (100000205 bp) in 2.445 CPU sec, 2.802 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 279718, 27, 40) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (261, 465, 903) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2187) [M::mem_pestat] mean and std.dev: (570.61, 420.25) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2829) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (159, 236, 338) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 696) [M::mem_pestat] mean and std.dev: (258.64, 126.12) [M::mem_pestat] low and high boundaries for proper pairs: (1, 875) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (500, 821, 2607) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6821) [M::mem_pestat] mean and std.dev: (1424.07, 1271.45) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8928) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (280, 942, 1691) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4513) [M::mem_pestat] mean and std.dev: (964.10, 798.92) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5924) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 700278 sequences (100000174 bp) in 1.706 CPU sec, 1.826 real sec... [M::mem_process_seqs] Processed 700994 reads in 187.610 CPU sec, 6.086 real sec [M::mem_process_seqs] Processed 700240 reads in 130.505 CPU sec, 4.288 real sec sorting block 59, #reads = 1066690 mem = 536877664 peak = 1163632640 [M::process] read 699738 sequences (100000090 bp) in 2.388 CPU sec, 2.746 real sec... [M::process] read 699582 sequences (100000076 bp) in 1.681 CPU sec, 1.787 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 280059, 35, 43) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (264, 552, 1376) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3600) [M::mem_pestat] mean and std.dev: (807.03, 713.68) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4712) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (159, 235, 337) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 693) [M::mem_pestat] mean and std.dev: (257.54, 125.25) [M::mem_pestat] low and high boundaries for proper pairs: (1, 871) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (213, 892, 2478) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7008) [M::mem_pestat] mean and std.dev: (1341.53, 1314.28) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9273) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (186, 227, 1352) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3684) [M::mem_pestat] mean and std.dev: (622.36, 715.28) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4850) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 700278 reads in 104.027 CPU sec, 3.375 real sec sorting block 60, #reads = 1067605 mem = 536877844 peak = 1163632640 [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 279754, 26, 54) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (167, 516, 1099) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2963) [M::mem_pestat] mean and std.dev: (556.13, 559.26) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3895) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (159, 236, 338) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 696) [M::mem_pestat] mean and std.dev: (258.82, 126.54) [M::mem_pestat] low and high boundaries for proper pairs: (1, 875) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (728, 1369, 1982) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4490) [M::mem_pestat] mean and std.dev: (1278.13, 882.51) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5744) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (249, 438, 761) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1785) [M::mem_pestat] mean and std.dev: (509.16, 387.67) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2297) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 280236, 37, 45) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (183, 360, 656) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1602) [M::mem_pestat] mean and std.dev: (412.51, 322.93) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2075) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (160, 237, 336) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 688) [M::mem_pestat] mean and std.dev: (257.81, 124.37) [M::mem_pestat] low and high boundaries for proper pairs: (1, 864) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (384, 1032, 3049) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8379) [M::mem_pestat] mean and std.dev: (1708.62, 1637.69) [M::mem_pestat] low and high boundaries for proper pairs: (1, 11044) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (182, 301, 622) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1502) [M::mem_pestat] mean and std.dev: (321.26, 235.88) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1942) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 699398 sequences (100000164 bp) in 1.829 CPU sec, 2.015 real sec... [M::mem_process_seqs] Processed 700384 reads in 297.093 CPU sec, 9.703 real sec [M::mem_process_seqs] Processed 699738 reads in 155.207 CPU sec, 5.147 real sec sorting block 61, #reads = 1067934 mem = 536879745 peak = 1163632640 [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 279789, 39, 35) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (159, 460, 1137) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3093) [M::mem_pestat] mean and std.dev: (604.95, 579.60) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4071) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (160, 237, 337) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 691) [M::mem_pestat] mean and std.dev: (258.59, 125.11) [M::mem_pestat] low and high boundaries for proper pairs: (1, 868) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (495, 1528, 2339) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6027) [M::mem_pestat] mean and std.dev: (1497.94, 1244.11) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7871) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (281, 366, 1275) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3263) [M::mem_pestat] mean and std.dev: (501.27, 460.88) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4257) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 699582 sequences (100000234 bp) in 2.428 CPU sec, 2.713 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 279749, 39, 49) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (175, 255, 1080) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2890) [M::mem_pestat] mean and std.dev: (475.71, 512.75) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3795) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (161, 238, 343) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 707) [M::mem_pestat] mean and std.dev: (261.64, 128.48) [M::mem_pestat] low and high boundaries for proper pairs: (1, 889) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (232, 1072, 2779) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7873) [M::mem_pestat] mean and std.dev: (1817.00, 1934.08) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10420) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (188, 298, 839) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2141) [M::mem_pestat] mean and std.dev: (443.34, 351.75) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2792) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 699466 sequences (100000257 bp) in 1.935 CPU sec, 1.988 real sec... [M::mem_process_seqs] Processed 699582 reads in 190.478 CPU sec, 6.220 real sec sorting block 62, #reads = 1068164 mem = 536885911 peak = 1163632640 [M::mem_process_seqs] Processed 699398 reads in 130.441 CPU sec, 4.227 real sec [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 279810, 26, 60) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (223, 273, 1312) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3490) [M::mem_pestat] mean and std.dev: (611.36, 606.83) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4579) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (160, 238, 343) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 709) [M::mem_pestat] mean and std.dev: (261.66, 129.19) [M::mem_pestat] low and high boundaries for proper pairs: (1, 892) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (596, 1238, 2040) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4928) [M::mem_pestat] mean and std.dev: (1426.28, 1251.18) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6431) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (199, 391, 959) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2479) [M::mem_pestat] mean and std.dev: (508.41, 439.05) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3239) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 699288 sequences (100000228 bp) in 2.403 CPU sec, 2.747 real sec... sorting block 63, #reads = 1067336 mem = 536880850 peak = 1189085184 [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 280174, 42, 50) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (244, 487, 1529) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4099) [M::mem_pestat] mean and std.dev: (848.79, 896.44) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5384) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (161, 238, 343) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 707) [M::mem_pestat] mean and std.dev: (261.99, 129.07) [M::mem_pestat] low and high boundaries for proper pairs: (1, 889) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (425, 1029, 2396) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6338) [M::mem_pestat] mean and std.dev: (1825.05, 2045.24) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10006) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (189, 420, 1468) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4026) [M::mem_pestat] mean and std.dev: (678.20, 714.74) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5305) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 705664 sequences (100000049 bp) in 1.765 CPU sec, 2.006 real sec... [M::mem_process_seqs] Processed 699582 reads in 191.111 CPU sec, 6.268 real sec [M::mem_process_seqs] Processed 699466 reads in 129.042 CPU sec, 4.193 real sec sorting block 64, #reads = 1067708 mem = 536878891 peak = 1189085184 [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 280131, 26, 50) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (190, 374, 817) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2071) [M::mem_pestat] mean and std.dev: (486.40, 384.67) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2698) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (161, 240, 347) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 719) [M::mem_pestat] mean and std.dev: (264.60, 131.54) [M::mem_pestat] low and high boundaries for proper pairs: (1, 905) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (188, 516, 1915) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5369) [M::mem_pestat] mean and std.dev: (1013.56, 1038.23) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7096) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (380, 634, 1627) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4121) [M::mem_pestat] mean and std.dev: (915.16, 742.55) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5368) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 708698 sequences (100000108 bp) in 2.331 CPU sec, 2.609 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 281866, 27, 44) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (192, 365, 660) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1596) [M::mem_pestat] mean and std.dev: (344.29, 244.60) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2064) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (151, 223, 322) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 664) [M::mem_pestat] mean and std.dev: (247.21, 123.40) [M::mem_pestat] low and high boundaries for proper pairs: (1, 835) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (524, 1393, 3863) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10541) [M::mem_pestat] mean and std.dev: (1982.67, 1804.40) [M::mem_pestat] low and high boundaries for proper pairs: (1, 13880) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (213, 770, 1708) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4698) [M::mem_pestat] mean and std.dev: (840.41, 877.66) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6193) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 706592 sequences (100000082 bp) in 1.902 CPU sec, 1.914 real sec... [M::mem_process_seqs] Processed 699288 reads in 197.066 CPU sec, 6.380 real sec [M::mem_process_seqs] Processed 705664 reads in 140.346 CPU sec, 4.540 real sec sorting block 65, #reads = 1067573 mem = 536878853 peak = 1189085184 [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 283624, 34, 34) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (185, 406, 1555) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4295) [M::mem_pestat] mean and std.dev: (709.40, 738.86) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5665) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (147, 214, 309) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 633) [M::mem_pestat] mean and std.dev: (238.02, 117.97) [M::mem_pestat] low and high boundaries for proper pairs: (1, 795) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (500, 1006, 1424) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3272) [M::mem_pestat] mean and std.dev: (932.53, 643.42) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4196) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (184, 297, 616) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1480) [M::mem_pestat] mean and std.dev: (329.93, 239.47) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1912) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 704902 sequences (100000271 bp) in 2.419 CPU sec, 2.745 real sec... [M::process] read 704032 sequences (100000248 bp) in 1.732 CPU sec, 1.738 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 282615, 21, 51) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (220, 530, 1337) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3571) [M::mem_pestat] mean and std.dev: (737.98, 652.58) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4688) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (150, 219, 318) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 654) [M::mem_pestat] mean and std.dev: (244.23, 121.85) [M::mem_pestat] low and high boundaries for proper pairs: (1, 822) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (348, 1078, 2847) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7845) [M::mem_pestat] mean and std.dev: (1527.81, 1467.95) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10344) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (192, 401, 925) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2391) [M::mem_pestat] mean and std.dev: (520.72, 483.41) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3124) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 708698 reads in 196.926 CPU sec, 6.343 real sec sorting block 66, #reads = 1067831 mem = 536878956 peak = 1189085184 [M::mem_process_seqs] Processed 706592 reads in 134.310 CPU sec, 4.314 real sec [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 282535, 16, 48) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (228, 581, 1468) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3948) [M::mem_pestat] mean and std.dev: (609.00, 514.61) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5188) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (152, 224, 326) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 674) [M::mem_pestat] mean and std.dev: (249.07, 124.88) [M::mem_pestat] low and high boundaries for proper pairs: (1, 848) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (710, 726, 1624) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3452) [M::mem_pestat] mean and std.dev: (952.80, 665.83) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4366) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (239, 432, 1988) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5486) [M::mem_pestat] mean and std.dev: (967.57, 1170.02) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7235) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR sorting block 67, #reads = 1070896 mem = 536879064 peak = 1189085184 [M::process] read 703402 sequences (100000191 bp) in 2.449 CPU sec, 2.770 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 282381, 22, 45) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (189, 478, 1315) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3567) [M::mem_pestat] mean and std.dev: (533.38, 485.82) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4693) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (154, 227, 331) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 685) [M::mem_pestat] mean and std.dev: (252.81, 127.39) [M::mem_pestat] low and high boundaries for proper pairs: (1, 862) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (192, 795, 1520) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4176) [M::mem_pestat] mean and std.dev: (1057.00, 1064.72) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5504) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (205, 366, 1312) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3526) [M::mem_pestat] mean and std.dev: (833.41, 1004.57) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4852) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 702674 sequences (100000196 bp) in 1.856 CPU sec, 1.877 real sec... [M::mem_process_seqs] Processed 704902 reads in 189.806 CPU sec, 6.158 real sec [M::process] read 702664 sequences (100000274 bp) in 2.041 CPU sec, 2.070 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 282042, 34, 46) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (247, 742, 2446) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6844) [M::mem_pestat] mean and std.dev: (1448.14, 1519.79) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9043) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (154, 228, 333) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 691) [M::mem_pestat] mean and std.dev: (253.95, 127.72) [M::mem_pestat] low and high boundaries for proper pairs: (1, 870) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (270, 1062, 2534) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7062) [M::mem_pestat] mean and std.dev: (1532.79, 1394.95) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9326) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (257, 291, 1695) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4571) [M::mem_pestat] mean and std.dev: (827.20, 909.57) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6009) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 703402 reads in 104.758 CPU sec, 3.482 real sec sorting block 68, #reads = 1072212 mem = 536883513 peak = 1189085184 [M::mem_process_seqs] Processed 704032 reads in 278.771 CPU sec, 9.116 real sec sorting block 69, #reads = 1072186 mem = 536882108 peak = 1189085184 [M::process] read 702604 sequences (100000146 bp) in 2.459 CPU sec, 2.823 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 281346, 28, 56) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (278, 571, 757) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1715) [M::mem_pestat] mean and std.dev: (468.25, 283.16) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2194) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (156, 230, 336) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 696) [M::mem_pestat] mean and std.dev: (256.61, 129.29) [M::mem_pestat] low and high boundaries for proper pairs: (1, 876) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (295, 597, 1792) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4786) [M::mem_pestat] mean and std.dev: (1110.75, 1019.27) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6283) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (292, 488, 1039) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2533) [M::mem_pestat] mean and std.dev: (659.78, 586.79) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3280) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 702162 sequences (100000137 bp) in 1.752 CPU sec, 1.773 real sec... [M::mem_process_seqs] Processed 702664 reads in 111.706 CPU sec, 3.608 real sec [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 281222, 36, 32) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (191, 325, 625) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1493) [M::mem_pestat] mean and std.dev: (445.03, 381.35) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1970) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (155, 229, 333) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 689) [M::mem_pestat] mean and std.dev: (254.80, 127.78) [M::mem_pestat] low and high boundaries for proper pairs: (1, 867) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (394, 814, 1414) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3454) [M::mem_pestat] mean and std.dev: (904.88, 710.22) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4474) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (264, 353, 1347) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3513) [M::mem_pestat] mean and std.dev: (536.21, 456.50) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4596) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 281117, 20, 42) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (211, 758, 1625) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4453) [M::mem_pestat] mean and std.dev: (910.76, 872.21) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5867) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (156, 231, 336) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 696) [M::mem_pestat] mean and std.dev: (256.43, 128.74) [M::mem_pestat] low and high boundaries for proper pairs: (1, 876) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (224, 981, 3062) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8738) [M::mem_pestat] mean and std.dev: (1106.00, 1077.21) [M::mem_pestat] low and high boundaries for proper pairs: (1, 11576) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (214, 424, 596) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1360) [M::mem_pestat] mean and std.dev: (414.63, 254.81) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1742) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 701540 sequences (100000246 bp) in 2.121 CPU sec, 2.141 real sec... [M::mem_process_seqs] Processed 702674 reads in 319.747 CPU sec, 10.377 real sec sorting block 70, #reads = 1069746 mem = 536879189 peak = 1189085184 [M::mem_process_seqs] Processed 702604 reads in 155.651 CPU sec, 5.034 real sec [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 281463, 25, 42) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (210, 602, 1124) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2952) [M::mem_pestat] mean and std.dev: (621.14, 471.89) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3866) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (157, 233, 341) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 709) [M::mem_pestat] mean and std.dev: (259.08, 130.44) [M::mem_pestat] low and high boundaries for proper pairs: (1, 893) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (190, 564, 952) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2476) [M::mem_pestat] mean and std.dev: (451.00, 410.16) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3238) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (184, 238, 422) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 898) [M::mem_pestat] mean and std.dev: (254.64, 137.68) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1136) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 701600 sequences (100000131 bp) in 2.332 CPU sec, 2.623 real sec... sorting block 71, #reads = 1069203 mem = 536878042 peak = 1189085184 [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 280093, 34, 45) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (265, 468, 1077) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2701) [M::mem_pestat] mean and std.dev: (628.93, 634.05) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3513) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (157, 233, 339) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 703) [M::mem_pestat] mean and std.dev: (258.51, 129.29) [M::mem_pestat] low and high boundaries for proper pairs: (1, 885) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (775, 1281, 2586) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6208) [M::mem_pestat] mean and std.dev: (1731.35, 1450.95) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8019) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (172, 415, 1299) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3553) [M::mem_pestat] mean and std.dev: (641.17, 705.07) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4680) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 701060 sequences (100000118 bp) in 1.950 CPU sec, 2.098 real sec... [M::mem_process_seqs] Processed 702162 reads in 196.045 CPU sec, 6.514 real sec [M::mem_process_seqs] Processed 701540 reads in 137.518 CPU sec, 4.444 real sec sorting block 72, #reads = 1067154 mem = 536880761 peak = 1189085184 [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 280318, 27, 61) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (254, 611, 857) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2063) [M::mem_pestat] mean and std.dev: (579.49, 413.41) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2666) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (157, 233, 340) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 706) [M::mem_pestat] mean and std.dev: (258.89, 129.73) [M::mem_pestat] low and high boundaries for proper pairs: (1, 889) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (454, 1412, 9792) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 28468) [M::mem_pestat] mean and std.dev: (3361.89, 3937.88) [M::mem_pestat] low and high boundaries for proper pairs: (1, 37806) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (215, 559, 1585) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4325) [M::mem_pestat] mean and std.dev: (926.44, 979.46) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5695) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 700770 sequences (100000001 bp) in 2.261 CPU sec, 2.545 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 279223, 17, 42) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (218, 513, 2578) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7298) [M::mem_pestat] mean and std.dev: (1188.20, 1435.10) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9658) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (158, 234, 340) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 704) [M::mem_pestat] mean and std.dev: (259.54, 129.93) [M::mem_pestat] low and high boundaries for proper pairs: (1, 886) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (362, 501, 785) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1631) [M::mem_pestat] mean and std.dev: (553.00, 381.39) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2079) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (199, 312, 1187) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3163) [M::mem_pestat] mean and std.dev: (689.17, 636.10) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4151) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 700780 sequences (100000048 bp) in 1.738 CPU sec, 1.825 real sec... [M::mem_process_seqs] Processed 701600 reads in 195.341 CPU sec, 6.315 real sec [M::mem_process_seqs] Processed 701060 reads in 135.747 CPU sec, 4.360 real sec sorting block 73, #reads = 1066679 mem = 536878305 peak = 1189085184 [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 279896, 19, 52) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (167, 261, 751) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1919) [M::mem_pestat] mean and std.dev: (331.33, 280.82) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2503) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (159, 235, 340) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 702) [M::mem_pestat] mean and std.dev: (259.67, 129.29) [M::mem_pestat] low and high boundaries for proper pairs: (1, 883) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (382, 1198, 1808) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4660) [M::mem_pestat] mean and std.dev: (949.67, 722.02) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6086) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (167, 307, 2042) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5792) [M::mem_pestat] mean and std.dev: (898.39, 1271.09) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7667) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 700556 sequences (100000243 bp) in 2.245 CPU sec, 2.555 real sec... [M::process] read 700212 sequences (100000196 bp) in 1.936 CPU sec, 1.990 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 279999, 37, 44) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (279, 428, 855) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2007) [M::mem_pestat] mean and std.dev: (449.32, 328.19) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2583) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (159, 234, 339) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 699) [M::mem_pestat] mean and std.dev: (258.66, 128.14) [M::mem_pestat] low and high boundaries for proper pairs: (1, 879) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (392, 1497, 4946) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 14054) [M::mem_pestat] mean and std.dev: (2648.46, 3046.02) [M::mem_pestat] low and high boundaries for proper pairs: (1, 18608) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (159, 341, 685) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1737) [M::mem_pestat] mean and std.dev: (326.55, 254.76) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2263) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 700770 reads in 195.348 CPU sec, 6.316 real sec sorting block 74, #reads = 1064781 mem = 536882132 peak = 1189085184 [M::mem_process_seqs] Processed 700780 reads in 136.487 CPU sec, 4.386 real sec sorting block 75, #reads = 1065734 mem = 536877266 peak = 1189085184 [M::process] read 700316 sequences (100000125 bp) in 2.387 CPU sec, 2.708 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 280040, 19, 48) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (178, 463, 871) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2257) [M::mem_pestat] mean and std.dev: (507.92, 461.26) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2950) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::process] read 700236 sequences (100000032 bp) in 1.787 CPU sec, 2.001 real sec... [M::mem_pestat] (25, 50, 75) percentile: (159, 236, 341) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 705) [M::mem_pestat] mean and std.dev: (260.56, 129.54) [M::mem_pestat] low and high boundaries for proper pairs: (1, 887) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (154, 314, 1211) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3325) [M::mem_pestat] mean and std.dev: (552.50, 630.74) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4382) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (241, 430, 2165) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6013) [M::mem_pestat] mean and std.dev: (1172.83, 1322.37) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7937) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 700212 reads in 113.041 CPU sec, 3.687 real sec [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 280250, 22, 65) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (212, 367, 1150) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3026) [M::mem_pestat] mean and std.dev: (648.90, 739.39) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3964) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (159, 235, 341) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 705) [M::mem_pestat] mean and std.dev: (260.10, 129.26) [M::mem_pestat] low and high boundaries for proper pairs: (1, 887) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (665, 905, 1634) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3572) [M::mem_pestat] mean and std.dev: (1040.45, 614.41) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4541) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (275, 471, 2986) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8408) [M::mem_pestat] mean and std.dev: (1458.48, 2083.90) [M::mem_pestat] low and high boundaries for proper pairs: (1, 11119) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 279764, 31, 41) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (220, 370, 1161) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3043) [M::mem_pestat] mean and std.dev: (586.00, 572.26) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3984) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (159, 235, 339) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 699) [M::mem_pestat] mean and std.dev: (259.59, 128.45) [M::mem_pestat] low and high boundaries for proper pairs: (1, 879) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (490, 733, 1773) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4339) [M::mem_pestat] mean and std.dev: (1200.23, 1066.44) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5622) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (214, 378, 1200) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3172) [M::mem_pestat] mean and std.dev: (605.84, 586.88) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4158) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 700210 sequences (100000041 bp) in 1.963 CPU sec, 1.986 real sec... [M::mem_process_seqs] Processed 700556 reads in 309.925 CPU sec, 10.110 real sec sorting block 76, #reads = 1066494 mem = 536878804 peak = 1189085184 [M::mem_process_seqs] Processed 700316 reads in 162.608 CPU sec, 5.411 real sec sorting block 77, #reads = 1065003 mem = 536879020 peak = 1189085184 [M::process] read 699948 sequences (100000004 bp) in 2.587 CPU sec, 2.938 real sec... [M::process] read 700236 sequences (100000184 bp) in 1.893 CPU sec, 1.953 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 279891, 23, 29) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (202, 302, 1035) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2701) [M::mem_pestat] mean and std.dev: (517.06, 458.60) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3534) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (159, 236, 341) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 705) [M::mem_pestat] mean and std.dev: (260.08, 128.63) [M::mem_pestat] low and high boundaries for proper pairs: (1, 887) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (300, 877, 3268) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9204) [M::mem_pestat] mean and std.dev: (1771.04, 1751.22) [M::mem_pestat] low and high boundaries for proper pairs: (1, 12172) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (221, 438, 1457) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3929) [M::mem_pestat] mean and std.dev: (871.39, 919.25) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5165) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 700210 reads in 109.750 CPU sec, 3.595 real sec [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 279823, 29, 65) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (204, 673, 1929) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5379) [M::mem_pestat] mean and std.dev: (1182.86, 1277.55) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7104) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (160, 236, 341) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 703) [M::mem_pestat] mean and std.dev: (260.27, 128.48) [M::mem_pestat] low and high boundaries for proper pairs: (1, 884) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (250, 1056, 3759) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10777) [M::mem_pestat] mean and std.dev: (1827.83, 2256.07) [M::mem_pestat] low and high boundaries for proper pairs: (1, 14286) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (245, 512, 1337) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3521) [M::mem_pestat] mean and std.dev: (884.19, 955.53) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4706) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 279847, 21, 58) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (229, 359, 1177) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3073) [M::mem_pestat] mean and std.dev: (680.71, 645.98) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4021) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (160, 237, 341) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 703) [M::mem_pestat] mean and std.dev: (260.61, 128.82) [M::mem_pestat] low and high boundaries for proper pairs: (1, 884) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (397, 766, 3730) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10396) [M::mem_pestat] mean and std.dev: (1494.62, 1567.91) [M::mem_pestat] low and high boundaries for proper pairs: (1, 13729) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (251, 685, 2671) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7511) [M::mem_pestat] mean and std.dev: (1388.82, 1550.84) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9931) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 699650 sequences (100000024 bp) in 1.966 CPU sec, 2.007 real sec... [M::mem_process_seqs] Processed 700236 reads in 310.034 CPU sec, 10.136 real sec sorting block 78, #reads = 1065131 mem = 536879073 peak = 1189085184 [M::mem_process_seqs] Processed 699948 reads in 161.269 CPU sec, 5.307 real sec [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 279731, 21, 48) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (242, 346, 959) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2393) [M::mem_pestat] mean and std.dev: (542.60, 541.29) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3110) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (160, 236, 341) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 703) [M::mem_pestat] mean and std.dev: (260.44, 128.94) [M::mem_pestat] low and high boundaries for proper pairs: (1, 884) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (472, 755, 1084) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2308) [M::mem_pestat] mean and std.dev: (663.56, 362.83) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2920) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (229, 443, 1056) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2710) [M::mem_pestat] mean and std.dev: (651.26, 577.31) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3537) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 699704 sequences (100000192 bp) in 2.190 CPU sec, 2.694 real sec... sorting block 79, #reads = 1064748 mem = 536878692 peak = 1189085184 [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 280003, 36, 55) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (199, 465, 1671) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4615) [M::mem_pestat] mean and std.dev: (868.43, 1061.18) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6087) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (160, 238, 344) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 712) [M::mem_pestat] mean and std.dev: (262.45, 130.42) [M::mem_pestat] low and high boundaries for proper pairs: (1, 896) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (586, 1582, 2530) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6418) [M::mem_pestat] mean and std.dev: (1970.06, 1756.41) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8996) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (177, 310, 1846) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5184) [M::mem_pestat] mean and std.dev: (701.22, 896.27) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6853) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 707974 sequences (100000056 bp) in 2.042 CPU sec, 2.142 real sec... [M::mem_process_seqs] Processed 700236 reads in 199.876 CPU sec, 6.543 real sec [M::process] read 711232 sequences (100000046 bp) in 1.931 CPU sec, 1.999 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 283021, 26, 39) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (229, 525, 1575) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4267) [M::mem_pestat] mean and std.dev: (744.50, 670.38) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5613) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (148, 217, 314) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 646) [M::mem_pestat] mean and std.dev: (241.31, 120.12) [M::mem_pestat] low and high boundaries for proper pairs: (1, 812) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (413, 979, 1780) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4514) [M::mem_pestat] mean and std.dev: (1053.16, 795.11) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5881) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (187, 358, 566) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1324) [M::mem_pestat] mean and std.dev: (432.63, 338.51) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1787) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 707974 reads in 113.123 CPU sec, 3.832 real sec sorting block 80, #reads = 1065419 mem = 536877953 peak = 1189085184 [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 280078, 20, 28) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (156, 428, 975) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2613) [M::mem_pestat] mean and std.dev: (606.78, 599.79) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3432) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (160, 238, 344) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 712) [M::mem_pestat] mean and std.dev: (262.58, 130.50) [M::mem_pestat] low and high boundaries for proper pairs: (1, 896) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (510, 1082, 3299) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8877) [M::mem_pestat] mean and std.dev: (1637.60, 1512.28) [M::mem_pestat] low and high boundaries for proper pairs: (1, 11666) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (235, 552, 1939) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5347) [M::mem_pestat] mean and std.dev: (1077.79, 1084.48) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7051) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 699704 reads in 228.492 CPU sec, 8.079 real sec [M::process] read 710660 sequences (100000139 bp) in 2.552 CPU sec, 2.699 real sec... sorting block 81, #reads = 1065992 mem = 536880953 peak = 1189085184 [M::mem_process_seqs] Processed 699650 reads in 426.342 CPU sec, 14.415 real sec [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 284380, 24, 47) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (290, 532, 1607) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4241) [M::mem_pestat] mean and std.dev: (976.36, 928.18) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5558) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (144, 210, 301) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 615) [M::mem_pestat] mean and std.dev: (232.66, 114.26) [M::mem_pestat] low and high boundaries for proper pairs: (1, 772) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (270, 852, 2203) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6069) [M::mem_pestat] mean and std.dev: (1240.50, 1144.50) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8002) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (177, 316, 830) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2136) [M::mem_pestat] mean and std.dev: (400.82, 362.99) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2789) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 708500 sequences (100000078 bp) in 2.054 CPU sec, 2.353 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 284777, 19, 45) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (194, 447, 1283) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3461) [M::mem_pestat] mean and std.dev: (805.03, 822.84) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4550) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (145, 211, 303) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 619) [M::mem_pestat] mean and std.dev: (233.81, 114.94) [M::mem_pestat] low and high boundaries for proper pairs: (1, 777) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (496, 791, 2003) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5017) [M::mem_pestat] mean and std.dev: (1090.24, 1294.81) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6524) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (200, 256, 630) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1490) [M::mem_pestat] mean and std.dev: (406.48, 332.69) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1920) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 707048 sequences (100000008 bp) in 1.911 CPU sec, 1.916 real sec... [M::mem_process_seqs] Processed 711232 reads in 240.744 CPU sec, 7.723 real sec sorting block 82, #reads = 1067928 mem = 536879680 peak = 1189085184 [M::mem_process_seqs] Processed 710660 reads in 148.423 CPU sec, 4.747 real sec [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 283750, 23, 46) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (195, 447, 1783) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4959) [M::mem_pestat] mean and std.dev: (879.83, 854.90) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6547) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (148, 215, 310) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 634) [M::mem_pestat] mean and std.dev: (238.88, 117.68) [M::mem_pestat] low and high boundaries for proper pairs: (1, 796) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (289, 666, 1337) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3433) [M::mem_pestat] mean and std.dev: (712.86, 603.55) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4481) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (216, 344, 524) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1140) [M::mem_pestat] mean and std.dev: (352.23, 244.36) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1448) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 706416 sequences (100000093 bp) in 2.406 CPU sec, 2.872 real sec... sorting block 83, #reads = 1068065 mem = 536884554 peak = 1189085184 [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 283524, 19, 48) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (190, 341, 1120) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2980) [M::mem_pestat] mean and std.dev: (417.81, 419.30) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3910) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (150, 219, 317) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 651) [M::mem_pestat] mean and std.dev: (243.30, 120.40) [M::mem_pestat] low and high boundaries for proper pairs: (1, 818) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (593, 1097, 2646) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6752) [M::mem_pestat] mean and std.dev: (1319.44, 1185.06) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8805) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (218, 344, 1051) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2717) [M::mem_pestat] mean and std.dev: (488.60, 490.28) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3550) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 705844 sequences (100000037 bp) in 2.040 CPU sec, 2.337 real sec... [M::mem_process_seqs] Processed 708500 reads in 211.154 CPU sec, 6.943 real sec [M::mem_process_seqs] Processed 707048 reads in 140.167 CPU sec, 4.654 real sec sorting block 84, #reads = 1065663 mem = 536880635 peak = 1189085184 [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 283064, 18, 52) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (190, 346, 1174) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3142) [M::mem_pestat] mean and std.dev: (579.86, 648.49) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4126) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (150, 220, 318) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 654) [M::mem_pestat] mean and std.dev: (244.39, 121.16) [M::mem_pestat] low and high boundaries for proper pairs: (1, 822) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (273, 1475, 2701) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7557) [M::mem_pestat] mean and std.dev: (1398.17, 1129.19) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9985) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (230, 385, 1648) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4484) [M::mem_pestat] mean and std.dev: (917.72, 903.89) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5902) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 705258 sequences (100000061 bp) in 2.229 CPU sec, 2.830 real sec... [M::process] read 705562 sequences (100000156 bp) in 1.924 CPU sec, 1.928 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 282768, 19, 36) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (186, 264, 1336) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3636) [M::mem_pestat] mean and std.dev: (559.58, 638.93) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4786) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (151, 221, 323) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 667) [M::mem_pestat] mean and std.dev: (247.13, 123.51) [M::mem_pestat] low and high boundaries for proper pairs: (1, 839) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (681, 1333, 2250) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5388) [M::mem_pestat] mean and std.dev: (1431.79, 1023.22) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6957) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (215, 323, 740) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1790) [M::mem_pestat] mean and std.dev: (474.11, 353.37) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2315) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 706416 reads in 208.640 CPU sec, 6.900 real sec [M::mem_process_seqs] Processed 705844 reads in 139.963 CPU sec, 4.547 real sec sorting block 85, #reads = 1066960 mem = 536882392 peak = 1189085184 [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 282468, 40, 49) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (130, 205, 385) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 895) [M::mem_pestat] mean and std.dev: (217.17, 116.37) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1150) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (152, 224, 326) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 674) [M::mem_pestat] mean and std.dev: (249.20, 124.60) [M::mem_pestat] low and high boundaries for proper pairs: (1, 848) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (310, 881, 1575) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4105) [M::mem_pestat] mean and std.dev: (929.59, 867.48) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5370) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (208, 399, 668) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1588) [M::mem_pestat] mean and std.dev: (377.50, 256.15) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2048) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 704854 sequences (100000085 bp) in 2.481 CPU sec, 2.928 real sec... [M::process] read 704466 sequences (100000130 bp) in 1.986 CPU sec, 2.081 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 282899, 15, 48) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (281, 479, 2253) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6197) [M::mem_pestat] mean and std.dev: (877.77, 876.11) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8169) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (152, 223, 325) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 671) [M::mem_pestat] mean and std.dev: (248.43, 123.97) [M::mem_pestat] low and high boundaries for proper pairs: (1, 844) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (404, 693, 1659) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4169) [M::mem_pestat] mean and std.dev: (1050.80, 1086.13) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5424) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (208, 624, 822) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2050) [M::mem_pestat] mean and std.dev: (539.95, 420.40) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2664) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 705258 reads in 205.476 CPU sec, 6.672 real sec sorting block 86, #reads = 1067117 mem = 536879151 peak = 1189085184 [M::mem_process_seqs] Processed 705562 reads in 139.037 CPU sec, 4.557 real sec [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 282033, 38, 42) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (279, 588, 2035) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5547) [M::mem_pestat] mean and std.dev: (1182.45, 1350.84) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7303) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (153, 225, 328) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 678) [M::mem_pestat] mean and std.dev: (250.27, 124.87) [M::mem_pestat] low and high boundaries for proper pairs: (1, 853) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (503, 598, 2585) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6749) [M::mem_pestat] mean and std.dev: (1366.06, 1474.77) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8831) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (181, 299, 776) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1966) [M::mem_pestat] mean and std.dev: (403.86, 415.12) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2561) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR sorting block 87, #reads = 1067853 mem = 536879179 peak = 1189085184 [M::process] read 704044 sequences (100000126 bp) in 2.476 CPU sec, 2.703 real sec... [M::process] read 703422 sequences (100000217 bp) in 1.926 CPU sec, 1.936 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 281826, 33, 33) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (157, 298, 589) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1453) [M::mem_pestat] mean and std.dev: (355.53, 279.91) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1885) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (153, 226, 329) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 681) [M::mem_pestat] mean and std.dev: (251.72, 126.18) [M::mem_pestat] low and high boundaries for proper pairs: (1, 857) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (218, 732, 1780) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4904) [M::mem_pestat] mean and std.dev: (1088.47, 1248.63) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6466) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (266, 424, 1023) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2537) [M::mem_pestat] mean and std.dev: (630.23, 611.51) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3294) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 704854 reads in 206.049 CPU sec, 6.815 real sec [M::mem_process_seqs] Processed 704466 reads in 141.224 CPU sec, 4.614 real sec sorting block 88, #reads = 1067840 mem = 536878823 peak = 1189085184 [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 281030, 29, 56) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (204, 326, 940) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2412) [M::mem_pestat] mean and std.dev: (599.84, 620.28) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3148) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (154, 228, 332) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 688) [M::mem_pestat] mean and std.dev: (253.27, 126.96) [M::mem_pestat] low and high boundaries for proper pairs: (1, 866) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (213, 700, 2466) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6972) [M::mem_pestat] mean and std.dev: (957.76, 1093.56) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9225) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (214, 360, 742) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1798) [M::mem_pestat] mean and std.dev: (468.34, 357.25) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2326) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 702358 sequences (100000102 bp) in 2.487 CPU sec, 3.010 real sec... [M::process] read 701990 sequences (100000124 bp) in 2.000 CPU sec, 2.073 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 281472, 32, 45) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (174, 337, 1120) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3012) [M::mem_pestat] mean and std.dev: (653.74, 731.41) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3958) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (155, 229, 333) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 689) [M::mem_pestat] mean and std.dev: (254.19, 127.19) [M::mem_pestat] low and high boundaries for proper pairs: (1, 867) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (269, 745, 1631) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4355) [M::mem_pestat] mean and std.dev: (1031.34, 965.50) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5717) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (168, 318, 1863) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5253) [M::mem_pestat] mean and std.dev: (588.61, 785.16) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6948) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 704044 reads in 208.019 CPU sec, 6.758 real sec [M::mem_process_seqs] Processed 703422 reads in 141.537 CPU sec, 4.581 real sec sorting block 89, #reads = 1066952 mem = 536883366 peak = 1189085184 [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 280344, 21, 53) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (197, 594, 2037) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5717) [M::mem_pestat] mean and std.dev: (1182.04, 1303.85) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7557) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (156, 231, 335) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 693) [M::mem_pestat] mean and std.dev: (256.11, 127.68) [M::mem_pestat] low and high boundaries for proper pairs: (1, 872) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (520, 806, 2229) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5647) [M::mem_pestat] mean and std.dev: (1203.33, 951.00) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7356) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (207, 326, 1307) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3507) [M::mem_pestat] mean and std.dev: (592.02, 725.38) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4607) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 701428 sequences (100000186 bp) in 2.491 CPU sec, 2.927 real sec... [M::process] read 700942 sequences (100000142 bp) in 1.965 CPU sec, 2.083 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 280865, 29, 55) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (259, 495, 1733) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4681) [M::mem_pestat] mean and std.dev: (933.75, 855.41) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6155) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (157, 232, 337) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 697) [M::mem_pestat] mean and std.dev: (257.08, 127.89) [M::mem_pestat] low and high boundaries for proper pairs: (1, 877) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (421, 575, 1675) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4183) [M::mem_pestat] mean and std.dev: (896.68, 756.12) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5437) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (215, 265, 1019) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2627) [M::mem_pestat] mean and std.dev: (654.96, 686.35) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3431) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 702358 reads in 209.035 CPU sec, 6.858 real sec sorting block 90, #reads = 1065552 mem = 536882227 peak = 1189085184 [M::mem_process_seqs] Processed 701990 reads in 143.503 CPU sec, 4.625 real sec [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 280201, 29, 71) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (238, 413, 465) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 919) [M::mem_pestat] mean and std.dev: (332.69, 172.66) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1146) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (158, 234, 339) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 701) [M::mem_pestat] mean and std.dev: (258.69, 128.90) [M::mem_pestat] low and high boundaries for proper pairs: (1, 882) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (220, 553, 2063) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5749) [M::mem_pestat] mean and std.dev: (1314.03, 1493.19) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7592) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (236, 410, 1084) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2780) [M::mem_pestat] mean and std.dev: (565.10, 507.26) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3628) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 701284 sequences (100000107 bp) in 2.459 CPU sec, 3.095 real sec... sorting block 91, #reads = 1065309 mem = 536878491 peak = 1189085184 [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 280245, 30, 48) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (220, 345, 814) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2002) [M::mem_pestat] mean and std.dev: (473.33, 440.80) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2596) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (158, 234, 339) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 701) [M::mem_pestat] mean and std.dev: (259.01, 128.82) [M::mem_pestat] low and high boundaries for proper pairs: (1, 882) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (400, 1497, 2560) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6880) [M::mem_pestat] mean and std.dev: (1602.89, 1752.64) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9040) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (154, 337, 2160) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6172) [M::mem_pestat] mean and std.dev: (1165.64, 1667.00) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8178) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 701228 sequences (100000114 bp) in 1.940 CPU sec, 1.962 real sec... [M::mem_process_seqs] Processed 701428 reads in 202.337 CPU sec, 6.596 real sec [M::mem_process_seqs] Processed 700942 reads in 138.813 CPU sec, 4.560 real sec sorting block 92, #reads = 1065961 mem = 536882635 peak = 1189085184 [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 280053, 43, 31) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (193, 307, 693) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1693) [M::mem_pestat] mean and std.dev: (329.53, 232.23) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2193) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (158, 234, 338) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 698) [M::mem_pestat] mean and std.dev: (258.42, 128.43) [M::mem_pestat] low and high boundaries for proper pairs: (1, 878) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (532, 897, 1724) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4108) [M::mem_pestat] mean and std.dev: (1082.62, 866.59) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5300) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (166, 260, 432) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 964) [M::mem_pestat] mean and std.dev: (312.96, 201.42) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1230) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 699750 sequences (100000205 bp) in 2.493 CPU sec, 2.715 real sec... [M::process] read 699124 sequences (100000121 bp) in 1.950 CPU sec, 2.042 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 280344, 25, 51) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (242, 567, 1297) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3407) [M::mem_pestat] mean and std.dev: (669.06, 598.53) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4462) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (158, 234, 339) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 701) [M::mem_pestat] mean and std.dev: (258.67, 128.34) [M::mem_pestat] low and high boundaries for proper pairs: (1, 882) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (229, 1114, 2144) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5974) [M::mem_pestat] mean and std.dev: (838.14, 865.32) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7889) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (305, 507, 1236) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3098) [M::mem_pestat] mean and std.dev: (700.32, 620.72) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4029) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 701284 reads in 205.406 CPU sec, 6.775 real sec [M::mem_process_seqs] Processed 701228 reads in 142.225 CPU sec, 4.625 real sec sorting block 93, #reads = 1066468 mem = 536881170 peak = 1189085184 [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 280302, 27, 47) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (249, 375, 1489) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3969) [M::mem_pestat] mean and std.dev: (764.87, 821.04) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5209) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (160, 237, 343) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 709) [M::mem_pestat] mean and std.dev: (261.58, 129.72) [M::mem_pestat] low and high boundaries for proper pairs: (1, 892) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (291, 507, 1144) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2850) [M::mem_pestat] mean and std.dev: (660.25, 627.87) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3703) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (177, 245, 396) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 834) [M::mem_pestat] mean and std.dev: (257.66, 127.30) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1053) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 699692 sequences (100000054 bp) in 2.414 CPU sec, 2.990 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 279028, 32, 52) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (162, 316, 603) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1485) [M::mem_pestat] mean and std.dev: (345.27, 254.98) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1926) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (161, 239, 344) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 710) [M::mem_pestat] mean and std.dev: (262.85, 129.86) [M::mem_pestat] low and high boundaries for proper pairs: (1, 893) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (216, 575, 2042) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5694) [M::mem_pestat] mean and std.dev: (958.47, 958.82) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7520) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (197, 355, 932) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2402) [M::mem_pestat] mean and std.dev: (493.88, 342.10) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3137) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 700992 sequences (100000020 bp) in 1.963 CPU sec, 1.993 real sec... [M::mem_process_seqs] Processed 699750 reads in 194.395 CPU sec, 6.323 real sec sorting block 94, #reads = 1064843 mem = 536878617 peak = 1189085184 [M::mem_process_seqs] Processed 699124 reads in 138.270 CPU sec, 4.463 real sec [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 280122, 22, 34) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (187, 338, 700) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1726) [M::mem_pestat] mean and std.dev: (408.00, 383.16) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2239) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (160, 237, 343) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 709) [M::mem_pestat] mean and std.dev: (261.89, 130.33) [M::mem_pestat] low and high boundaries for proper pairs: (1, 892) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (243, 614, 878) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2148) [M::mem_pestat] mean and std.dev: (427.22, 283.17) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2783) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (151, 331, 609) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1525) [M::mem_pestat] mean and std.dev: (408.23, 303.22) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1983) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 705974 sequences (100000094 bp) in 2.469 CPU sec, 2.824 real sec... [M::process] read 708472 sequences (100000197 bp) in 1.895 CPU sec, 1.915 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 279692, 32, 51) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (189, 312, 1055) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2787) [M::mem_pestat] mean and std.dev: (654.24, 677.84) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3653) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (158, 234, 338) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 698) [M::mem_pestat] mean and std.dev: (258.72, 128.85) [M::mem_pestat] low and high boundaries for proper pairs: (1, 878) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (132, 532, 1550) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4386) [M::mem_pestat] mean and std.dev: (945.62, 989.15) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5804) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (206, 434, 1321) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3551) [M::mem_pestat] mean and std.dev: (827.18, 866.89) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4666) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 699692 reads in 198.587 CPU sec, 6.428 real sec sorting block 95, #reads = 1066383 mem = 536880758 peak = 1189085184 [M::mem_process_seqs] Processed 700992 reads in 141.263 CPU sec, 4.621 real sec sorting block 96, #reads = 1066757 mem = 536882803 peak = 1210576896 [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 281412, 20, 33) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (295, 496, 1388) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3574) [M::mem_pestat] mean and std.dev: (693.18, 698.86) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4667) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (151, 221, 321) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 661) [M::mem_pestat] mean and std.dev: (245.85, 122.56) [M::mem_pestat] low and high boundaries for proper pairs: (1, 831) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (168, 884, 2293) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6543) [M::mem_pestat] mean and std.dev: (899.00, 1129.83) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8668) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (157, 351, 764) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1978) [M::mem_pestat] mean and std.dev: (426.23, 399.49) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2585) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 707352 sequences (100000204 bp) in 2.338 CPU sec, 2.841 real sec... [M::process] read 706836 sequences (100000044 bp) in 1.869 CPU sec, 1.870 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 283891, 17, 37) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (136, 192, 345) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 763) [M::mem_pestat] mean and std.dev: (223.06, 147.39) [M::mem_pestat] low and high boundaries for proper pairs: (1, 972) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (148, 216, 312) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 640) [M::mem_pestat] mean and std.dev: (239.83, 118.64) [M::mem_pestat] low and high boundaries for proper pairs: (1, 804) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (253, 652, 1983) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5443) [M::mem_pestat] mean and std.dev: (1257.29, 1399.27) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7173) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (202, 621, 1057) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2767) [M::mem_pestat] mean and std.dev: (608.27, 474.10) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3622) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 705974 reads in 212.141 CPU sec, 6.963 real sec [M::mem_process_seqs] Processed 708472 reads in 134.511 CPU sec, 4.410 real sec sorting block 97, #reads = 1061967 mem = 536886625 peak = 1210576896 [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 283321, 19, 46) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (268, 431, 1254) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3226) [M::mem_pestat] mean and std.dev: (730.58, 825.99) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4212) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (149, 219, 317) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 653) [M::mem_pestat] mean and std.dev: (243.04, 120.49) [M::mem_pestat] low and high boundaries for proper pairs: (1, 821) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (835, 1430, 2987) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7291) [M::mem_pestat] mean and std.dev: (1300.73, 841.72) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9443) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (177, 398, 1300) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3546) [M::mem_pestat] mean and std.dev: (672.05, 663.77) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4669) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 705114 sequences (100000125 bp) in 2.380 CPU sec, 2.754 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 283537, 19, 43) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (285, 439, 1000) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2430) [M::mem_pestat] mean and std.dev: (536.58, 433.47) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3145) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (150, 221, 320) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 660) [M::mem_pestat] mean and std.dev: (245.33, 122.08) [M::mem_pestat] low and high boundaries for proper pairs: (1, 830) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (318, 612, 1422) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3630) [M::mem_pestat] mean and std.dev: (778.44, 584.72) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4734) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (216, 400, 1322) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3534) [M::mem_pestat] mean and std.dev: (754.31, 772.15) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4640) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 704738 sequences (100000182 bp) in 1.931 CPU sec, 1.944 real sec... [M::mem_process_seqs] Processed 707352 reads in 190.520 CPU sec, 6.237 real sec [M::mem_process_seqs] Processed 706836 reads in 126.310 CPU sec, 4.131 real sec sorting block 98, #reads = 1073558 mem = 536882550 peak = 1210576896 [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 282720, 22, 50) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (166, 263, 483) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1117) [M::mem_pestat] mean and std.dev: (323.97, 213.57) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1434) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (152, 224, 324) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 668) [M::mem_pestat] mean and std.dev: (248.04, 122.60) [M::mem_pestat] low and high boundaries for proper pairs: (1, 840) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (103, 861, 1832) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5290) [M::mem_pestat] mean and std.dev: (900.10, 926.72) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7019) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (277, 475, 1340) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3466) [M::mem_pestat] mean and std.dev: (715.48, 713.61) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4529) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 704228 sequences (100000071 bp) in 2.256 CPU sec, 2.790 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 282959, 16, 41) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (193, 317, 860) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2194) [M::mem_pestat] mean and std.dev: (443.97, 414.18) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2861) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (153, 226, 327) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 675) [M::mem_pestat] mean and std.dev: (249.89, 123.67) [M::mem_pestat] low and high boundaries for proper pairs: (1, 849) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (516, 1734, 3694) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10050) [M::mem_pestat] mean and std.dev: (1981.88, 2203.76) [M::mem_pestat] low and high boundaries for proper pairs: (1, 13228) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (243, 601, 1147) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2955) [M::mem_pestat] mean and std.dev: (797.52, 677.00) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3859) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 703548 sequences (100000042 bp) in 1.904 CPU sec, 1.950 real sec... [M::mem_process_seqs] Processed 705114 reads in 187.891 CPU sec, 6.205 real sec sorting block 99, #reads = 1073907 mem = 536881867 peak = 1210576896 [M::mem_process_seqs] Processed 704738 reads in 125.556 CPU sec, 4.114 real sec [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 282550, 20, 47) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (204, 577, 1526) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4170) [M::mem_pestat] mean and std.dev: (942.90, 1073.82) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5492) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (154, 228, 330) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 682) [M::mem_pestat] mean and std.dev: (252.33, 125.21) [M::mem_pestat] low and high boundaries for proper pairs: (1, 858) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (627, 2075, 2552) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6402) [M::mem_pestat] mean and std.dev: (1668.45, 960.85) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8327) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (186, 436, 984) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2580) [M::mem_pestat] mean and std.dev: (489.56, 405.55) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3378) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR sorting block 100, #reads = 1073348 mem = 536880088 peak = 1219198976 [M::process] read 703110 sequences (100000183 bp) in 2.359 CPU sec, 2.813 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 282225, 26, 43) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (275, 541, 899) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2147) [M::mem_pestat] mean and std.dev: (630.87, 488.68) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2771) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (154, 228, 331) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 685) [M::mem_pestat] mean and std.dev: (253.03, 125.47) [M::mem_pestat] low and high boundaries for proper pairs: (1, 862) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (330, 708, 1011) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2373) [M::mem_pestat] mean and std.dev: (600.81, 432.37) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3054) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (240, 432, 732) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1716) [M::mem_pestat] mean and std.dev: (449.11, 312.00) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2208) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 704020 sequences (100000275 bp) in 1.873 CPU sec, 1.995 real sec... [M::mem_process_seqs] Processed 704228 reads in 194.363 CPU sec, 6.396 real sec [M::mem_process_seqs] Processed 703548 reads in 134.406 CPU sec, 4.388 real sec sorting block 101, #reads = 1073001 mem = 536879413 peak = 1219198976 [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 281999, 35, 41) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (276, 380, 984) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2400) [M::mem_pestat] mean and std.dev: (563.09, 392.39) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3108) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (155, 229, 334) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 692) [M::mem_pestat] mean and std.dev: (254.37, 126.57) [M::mem_pestat] low and high boundaries for proper pairs: (1, 871) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (460, 935, 1533) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3679) [M::mem_pestat] mean and std.dev: (901.66, 672.65) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4752) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (177, 251, 1031) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2739) [M::mem_pestat] mean and std.dev: (509.76, 558.03) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3593) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 703292 sequences (100000035 bp) in 2.246 CPU sec, 2.772 real sec... [M::process] read 702824 sequences (100000181 bp) in 1.902 CPU sec, 1.965 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 282475, 21, 53) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (174, 545, 969) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2559) [M::mem_pestat] mean and std.dev: (616.86, 513.79) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3354) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (154, 228, 331) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 685) [M::mem_pestat] mean and std.dev: (252.30, 125.37) [M::mem_pestat] low and high boundaries for proper pairs: (1, 862) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (398, 1187, 1650) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4154) [M::mem_pestat] mean and std.dev: (1018.00, 923.39) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5406) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (218, 410, 1238) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3278) [M::mem_pestat] mean and std.dev: (646.10, 665.94) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4298) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 703110 reads in 196.984 CPU sec, 6.411 real sec [M::mem_process_seqs] Processed 704020 reads in 130.512 CPU sec, 4.223 real sec sorting block 102, #reads = 1069994 mem = 536880314 peak = 1219198976 [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 282095, 17, 26) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (184, 337, 777) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1963) [M::mem_pestat] mean and std.dev: (417.59, 339.84) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2556) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (155, 229, 333) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 689) [M::mem_pestat] mean and std.dev: (253.99, 126.10) [M::mem_pestat] low and high boundaries for proper pairs: (1, 867) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (454, 497, 1698) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4186) [M::mem_pestat] mean and std.dev: (993.82, 1045.23) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5430) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (209, 487, 702) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1688) [M::mem_pestat] mean and std.dev: (508.65, 454.81) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2328) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 702814 sequences (100000227 bp) in 2.501 CPU sec, 2.788 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 281891, 26, 47) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (184, 486, 1057) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2803) [M::mem_pestat] mean and std.dev: (622.86, 622.75) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3676) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (156, 231, 335) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 693) [M::mem_pestat] mean and std.dev: (255.55, 126.56) [M::mem_pestat] low and high boundaries for proper pairs: (1, 872) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (215, 899, 2261) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6353) [M::mem_pestat] mean and std.dev: (1528.04, 1530.18) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8399) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (250, 493, 1398) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3694) [M::mem_pestat] mean and std.dev: (853.57, 806.93) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4842) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 703558 sequences (100000245 bp) in 1.932 CPU sec, 1.934 real sec... [M::mem_process_seqs] Processed 703292 reads in 191.310 CPU sec, 6.201 real sec sorting block 103, #reads = 1071741 mem = 536885222 peak = 1219198976 [M::mem_process_seqs] Processed 702824 reads in 130.519 CPU sec, 4.187 real sec sorting block 104, #reads = 1069841 mem = 536878753 peak = 1228234752 [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 281253, 26, 33) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (218, 430, 1311) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3497) [M::mem_pestat] mean and std.dev: (787.98, 787.68) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4590) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (155, 230, 333) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 689) [M::mem_pestat] mean and std.dev: (254.09, 125.55) [M::mem_pestat] low and high boundaries for proper pairs: (1, 867) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (702, 1727, 2926) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7374) [M::mem_pestat] mean and std.dev: (1751.27, 1105.00) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9598) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (201, 326, 875) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2223) [M::mem_pestat] mean and std.dev: (384.32, 302.44) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2897) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 702694 sequences (100000068 bp) in 2.434 CPU sec, 2.686 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 281771, 16, 61) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (193, 384, 819) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2071) [M::mem_pestat] mean and std.dev: (486.31, 442.52) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2697) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (154, 227, 328) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 676) [M::mem_pestat] mean and std.dev: (250.91, 123.61) [M::mem_pestat] low and high boundaries for proper pairs: (1, 850) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (273, 440, 1031) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2547) [M::mem_pestat] mean and std.dev: (502.71, 422.18) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3305) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (226, 629, 1001) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2551) [M::mem_pestat] mean and std.dev: (619.66, 459.95) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3326) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 702050 sequences (100000011 bp) in 1.949 CPU sec, 2.066 real sec... [M::mem_process_seqs] Processed 702814 reads in 194.238 CPU sec, 6.300 real sec [M::process] read 702128 sequences (100000167 bp) in 2.074 CPU sec, 2.092 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 281181, 27, 50) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (386, 822, 1582) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3974) [M::mem_pestat] mean and std.dev: (932.50, 695.50) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5170) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (156, 231, 334) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 690) [M::mem_pestat] mean and std.dev: (255.24, 126.96) [M::mem_pestat] low and high boundaries for proper pairs: (1, 868) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (559, 1216, 1776) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4210) [M::mem_pestat] mean and std.dev: (1240.16, 747.62) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5427) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (146, 354, 1099) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3005) [M::mem_pestat] mean and std.dev: (602.70, 641.51) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3958) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 702694 reads in 111.409 CPU sec, 3.617 real sec sorting block 105, #reads = 1070084 mem = 536879401 peak = 1228234752 [M::mem_process_seqs] Processed 703558 reads in 289.566 CPU sec, 9.383 real sec [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 281047, 28, 46) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (288, 668, 1720) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4584) [M::mem_pestat] mean and std.dev: (1031.06, 1063.05) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6016) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (156, 232, 336) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 696) [M::mem_pestat] mean and std.dev: (256.63, 127.64) [M::mem_pestat] low and high boundaries for proper pairs: (1, 876) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (123, 539, 1003) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2763) [M::mem_pestat] mean and std.dev: (584.65, 615.36) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3643) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (171, 377, 674) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1680) [M::mem_pestat] mean and std.dev: (376.47, 275.33) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2183) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR sorting block 106, #reads = 1069227 mem = 536881903 peak = 1229017088 [M::process] read 701672 sequences (100000148 bp) in 2.419 CPU sec, 2.836 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 280896, 20, 47) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (178, 328, 985) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2599) [M::mem_pestat] mean and std.dev: (492.97, 451.89) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3406) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (157, 231, 336) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 694) [M::mem_pestat] mean and std.dev: (256.51, 127.68) [M::mem_pestat] low and high boundaries for proper pairs: (1, 873) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (398, 1398, 2825) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7679) [M::mem_pestat] mean and std.dev: (1952.50, 2118.93) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10428) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (215, 418, 2525) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7145) [M::mem_pestat] mean and std.dev: (1480.09, 1824.21) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9455) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 701924 sequences (100000044 bp) in 1.883 CPU sec, 1.934 real sec... [M::mem_process_seqs] Processed 702050 reads in 229.290 CPU sec, 7.483 real sec [M::mem_process_seqs] Processed 702128 reads in 141.235 CPU sec, 4.674 real sec sorting block 107, #reads = 1067529 mem = 536879337 peak = 1229017088 [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 280303, 21, 40) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (182, 310, 755) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1901) [M::mem_pestat] mean and std.dev: (505.81, 435.02) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2474) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (158, 232, 336) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 692) [M::mem_pestat] mean and std.dev: (257.06, 127.69) [M::mem_pestat] low and high boundaries for proper pairs: (1, 870) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (551, 752, 4462) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12284) [M::mem_pestat] mean and std.dev: (2175.81, 2522.97) [M::mem_pestat] low and high boundaries for proper pairs: (1, 16195) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (173, 388, 578) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1388) [M::mem_pestat] mean and std.dev: (382.75, 317.01) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1793) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 701350 sequences (100000259 bp) in 2.215 CPU sec, 2.509 real sec... [M::process] read 701120 sequences (100000244 bp) in 1.898 CPU sec, 1.921 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 280559, 30, 50) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (157, 262, 460) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1066) [M::mem_pestat] mean and std.dev: (276.97, 177.61) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1369) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (157, 231, 333) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 685) [M::mem_pestat] mean and std.dev: (255.44, 126.35) [M::mem_pestat] low and high boundaries for proper pairs: (1, 861) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (439, 1032, 1843) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4651) [M::mem_pestat] mean and std.dev: (1185.25, 1072.65) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6055) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (203, 382, 1017) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2645) [M::mem_pestat] mean and std.dev: (469.86, 419.28) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3459) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 701672 reads in 206.965 CPU sec, 6.739 real sec sorting block 108, #reads = 1065499 mem = 536885925 peak = 1229017088 [M::process] read 700808 sequences (100000135 bp) in 2.116 CPU sec, 2.187 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 279959, 23, 37) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (231, 753, 1799) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4935) [M::mem_pestat] mean and std.dev: (934.29, 851.58) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6503) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (158, 233, 336) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 692) [M::mem_pestat] mean and std.dev: (257.24, 126.88) [M::mem_pestat] low and high boundaries for proper pairs: (1, 870) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (392, 1411, 2494) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6698) [M::mem_pestat] mean and std.dev: (1417.39, 1114.33) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8800) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (272, 456, 1370) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3566) [M::mem_pestat] mean and std.dev: (767.78, 702.26) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4664) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 701350 reads in 113.398 CPU sec, 3.756 real sec [M::mem_process_seqs] Processed 701924 reads in 293.852 CPU sec, 9.561 real sec sorting block 109, #reads = 1065190 mem = 536882504 peak = 1229017088 [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 279772, 22, 46) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (253, 359, 2351) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6547) [M::mem_pestat] mean and std.dev: (899.83, 1226.04) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8645) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (158, 233, 336) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 692) [M::mem_pestat] mean and std.dev: (257.33, 127.62) [M::mem_pestat] low and high boundaries for proper pairs: (1, 870) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (103, 681, 1008) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2818) [M::mem_pestat] mean and std.dev: (621.10, 590.18) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3723) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (205, 314, 1086) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2848) [M::mem_pestat] mean and std.dev: (577.77, 620.87) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3729) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 700810 sequences (100000132 bp) in 2.308 CPU sec, 2.532 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 280219, 33, 45) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (258, 513, 1234) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3186) [M::mem_pestat] mean and std.dev: (658.90, 584.66) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4162) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (158, 234, 338) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 698) [M::mem_pestat] mean and std.dev: (258.71, 128.58) [M::mem_pestat] low and high boundaries for proper pairs: (1, 878) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (301, 1133, 1366) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3496) [M::mem_pestat] mean and std.dev: (1006.87, 769.20) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4561) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (163, 303, 907) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2395) [M::mem_pestat] mean and std.dev: (393.54, 369.25) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3139) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 700842 sequences (100000027 bp) in 1.920 CPU sec, 1.942 real sec... [M::mem_process_seqs] Processed 701120 reads in 233.667 CPU sec, 7.552 real sec sorting block 110, #reads = 1065151 mem = 536879357 peak = 1229017088 [M::mem_process_seqs] Processed 700808 reads in 144.652 CPU sec, 4.740 real sec [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 280198, 26, 38) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (126, 249, 921) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2511) [M::mem_pestat] mean and std.dev: (516.46, 627.26) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3306) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (159, 235, 339) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 699) [M::mem_pestat] mean and std.dev: (259.07, 128.64) [M::mem_pestat] low and high boundaries for proper pairs: (1, 879) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (67, 198, 2084) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6118) [M::mem_pestat] mean and std.dev: (865.92, 1018.89) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8135) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (178, 377, 2143) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6073) [M::mem_pestat] mean and std.dev: (1181.50, 1330.53) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8038) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 706446 sequences (100000196 bp) in 2.396 CPU sec, 2.695 real sec... [M::process] read 712902 sequences (100000189 bp) in 2.000 CPU sec, 2.007 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 279968, 37, 55) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (188, 433, 1668) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4628) [M::mem_pestat] mean and std.dev: (764.21, 901.62) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6108) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (158, 233, 337) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 695) [M::mem_pestat] mean and std.dev: (257.65, 127.40) [M::mem_pestat] low and high boundaries for proper pairs: (1, 874) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (426, 880, 1520) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3708) [M::mem_pestat] mean and std.dev: (942.52, 757.03) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4802) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (303, 390, 643) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1323) [M::mem_pestat] mean and std.dev: (408.83, 234.54) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1663) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 700810 reads in 214.945 CPU sec, 7.027 real sec sorting block 111, #reads = 1064573 mem = 536879682 peak = 1229017088 [M::mem_process_seqs] Processed 700842 reads in 151.713 CPU sec, 4.947 real sec sorting block 112, #reads = 1060608 mem = 536879266 peak = 1229017088 [M::process] read 711444 sequences (100000153 bp) in 2.432 CPU sec, 2.707 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 281472, 32, 50) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (236, 668, 1384) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3680) [M::mem_pestat] mean and std.dev: (803.22, 809.87) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4828) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (150, 220, 318) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 654) [M::mem_pestat] mean and std.dev: (244.16, 121.20) [M::mem_pestat] low and high boundaries for proper pairs: (1, 822) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (466, 915, 2450) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6418) [M::mem_pestat] mean and std.dev: (1356.93, 1533.32) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8402) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (187, 416, 729) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1813) [M::mem_pestat] mean and std.dev: (546.04, 470.31) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2427) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 709974 sequences (100000058 bp) in 1.954 CPU sec, 1.960 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 284802, 18, 27) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (200, 581, 1191) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3173) [M::mem_pestat] mean and std.dev: (713.39, 621.33) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4164) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (143, 206, 295) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 599) [M::mem_pestat] mean and std.dev: (228.20, 111.23) [M::mem_pestat] low and high boundaries for proper pairs: (1, 751) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (214, 568, 1507) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4093) [M::mem_pestat] mean and std.dev: (780.53, 780.24) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5386) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (202, 299, 756) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1864) [M::mem_pestat] mean and std.dev: (468.24, 398.85) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2418) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 283979, 23, 41) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (185, 327, 1427) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3911) [M::mem_pestat] mean and std.dev: (742.72, 862.50) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5153) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (144, 209, 302) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 618) [M::mem_pestat] mean and std.dev: (233.28, 114.96) [M::mem_pestat] low and high boundaries for proper pairs: (1, 776) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (506, 1080, 1814) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4430) [M::mem_pestat] mean and std.dev: (1128.36, 940.59) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5738) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (196, 265, 765) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1903) [M::mem_pestat] mean and std.dev: (430.36, 343.01) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2472) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 706446 reads in 322.848 CPU sec, 10.468 real sec [M::mem_process_seqs] Processed 712902 reads in 242.199 CPU sec, 7.787 real sec [M::mem_process_seqs] Processed 711444 reads in 269.642 CPU sec, 8.712 real sec sorting block 113, #reads = 1055633 mem = 536879509 peak = 1229017088 [M::process] read 708714 sequences (100000095 bp) in 2.385 CPU sec, 2.810 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 283936, 32, 31) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (184, 213, 600) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1432) [M::mem_pestat] mean and std.dev: (259.53, 190.15) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1848) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (146, 213, 308) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 632) [M::mem_pestat] mean and std.dev: (236.94, 116.89) [M::mem_pestat] low and high boundaries for proper pairs: (1, 794) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (119, 359, 1513) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4301) [M::mem_pestat] mean and std.dev: (757.74, 975.59) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5695) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (297, 552, 859) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1983) [M::mem_pestat] mean and std.dev: (499.56, 327.93) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2545) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR sorting block 114, #reads = 1068044 mem = 536881759 peak = 1229017088 [M::process] read 707542 sequences (100000134 bp) in 2.235 CPU sec, 2.443 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 283842, 24, 47) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (144, 234, 890) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2382) [M::mem_pestat] mean and std.dev: (377.57, 352.78) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3128) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (148, 216, 314) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 646) [M::mem_pestat] mean and std.dev: (240.66, 118.95) [M::mem_pestat] low and high boundaries for proper pairs: (1, 812) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (295, 793, 1164) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2902) [M::mem_pestat] mean and std.dev: (820.25, 649.24) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3771) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (172, 251, 480) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1096) [M::mem_pestat] mean and std.dev: (281.95, 208.17) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1404) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 709974 reads in 214.767 CPU sec, 7.012 real sec [M::process] read 706620 sequences (100000092 bp) in 1.849 CPU sec, 1.876 real sec... [M::mem_process_seqs] Processed 708714 reads in 148.734 CPU sec, 4.797 real sec sorting block 115, #reads = 1068253 mem = 536883091 peak = 1229017088 [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 283287, 21, 48) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (212, 459, 1409) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3803) [M::mem_pestat] mean and std.dev: (658.27, 675.48) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5000) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::process] read 705634 sequences (100000068 bp) in 2.189 CPU sec, 2.566 real sec... [M::mem_pestat] (25, 50, 75) percentile: (149, 219, 317) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 653) [M::mem_pestat] mean and std.dev: (243.08, 120.36) [M::mem_pestat] low and high boundaries for proper pairs: (1, 821) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (113, 759, 2277) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6605) [M::mem_pestat] mean and std.dev: (1122.67, 1263.84) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8769) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (174, 304, 622) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1518) [M::mem_pestat] mean and std.dev: (378.54, 372.58) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1966) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 705556 sequences (100000134 bp) in 1.842 CPU sec, 1.864 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 283337, 19, 52) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (181, 858, 1894) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5320) [M::mem_pestat] mean and std.dev: (1102.08, 985.63) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7033) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (150, 221, 321) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 663) [M::mem_pestat] mean and std.dev: (245.83, 121.94) [M::mem_pestat] low and high boundaries for proper pairs: (1, 834) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (334, 503, 1324) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3304) [M::mem_pestat] mean and std.dev: (709.44, 451.16) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4294) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (237, 324, 595) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1311) [M::mem_pestat] mean and std.dev: (337.98, 241.65) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1669) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 707542 reads in 208.382 CPU sec, 6.712 real sec sorting block 116, #reads = 1066183 mem = 536880663 peak = 1229017088 [M::mem_process_seqs] Processed 706620 reads in 142.958 CPU sec, 4.590 real sec [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 282202, 24, 37) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (242, 423, 836) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2024) [M::mem_pestat] mean and std.dev: (516.61, 393.54) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2618) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (151, 223, 325) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 673) [M::mem_pestat] mean and std.dev: (248.08, 123.33) [M::mem_pestat] low and high boundaries for proper pairs: (1, 847) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (492, 830, 2535) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6621) [M::mem_pestat] mean and std.dev: (1376.09, 1197.42) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8664) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (279, 1060, 2655) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7407) [M::mem_pestat] mean and std.dev: (1796.22, 1959.06) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9783) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 706062 sequences (100000060 bp) in 2.366 CPU sec, 2.992 real sec... [M::process] read 705322 sequences (100000116 bp) in 1.919 CPU sec, 1.924 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 281835, 38, 44) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (163, 196, 671) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1687) [M::mem_pestat] mean and std.dev: (361.39, 358.44) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2195) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (152, 223, 325) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 671) [M::mem_pestat] mean and std.dev: (248.64, 123.72) [M::mem_pestat] low and high boundaries for proper pairs: (1, 844) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (321, 641, 1165) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2853) [M::mem_pestat] mean and std.dev: (900.45, 750.41) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3902) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (177, 383, 621) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1509) [M::mem_pestat] mean and std.dev: (363.87, 231.16) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1953) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 705634 reads in 207.848 CPU sec, 6.701 real sec sorting block 117, #reads = 1067649 mem = 536878820 peak = 1229017088 [M::mem_process_seqs] Processed 705556 reads in 144.495 CPU sec, 4.620 real sec sorting block 118, #reads = 1066687 mem = 536878674 peak = 1229017088 [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 281694, 22, 39) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (277, 396, 1008) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2470) [M::mem_pestat] mean and std.dev: (514.62, 448.38) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3201) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (151, 222, 324) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 670) [M::mem_pestat] mean and std.dev: (247.68, 124.00) [M::mem_pestat] low and high boundaries for proper pairs: (1, 843) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (273, 914, 1886) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5112) [M::mem_pestat] mean and std.dev: (1185.48, 951.55) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6725) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (189, 362, 1069) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2829) [M::mem_pestat] mean and std.dev: (570.57, 510.48) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3709) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 706090 sequences (100000191 bp) in 2.554 CPU sec, 2.817 real sec... [M::process] read 704366 sequences (100000295 bp) in 1.778 CPU sec, 1.822 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 281686, 22, 45) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (204, 354, 1432) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3888) [M::mem_pestat] mean and std.dev: (787.18, 836.00) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5116) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (152, 225, 328) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 680) [M::mem_pestat] mean and std.dev: (250.40, 125.35) [M::mem_pestat] low and high boundaries for proper pairs: (1, 856) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (337, 658, 2326) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6304) [M::mem_pestat] mean and std.dev: (950.86, 863.41) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8293) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (268, 582, 1340) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3484) [M::mem_pestat] mean and std.dev: (804.72, 738.30) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4556) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 706062 reads in 209.181 CPU sec, 6.719 real sec [M::mem_process_seqs] Processed 705322 reads in 141.427 CPU sec, 4.550 real sec sorting block 119, #reads = 1064598 mem = 536878298 peak = 1229017088 [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 282468, 18, 47) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (188, 402, 760) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1904) [M::mem_pestat] mean and std.dev: (464.74, 366.43) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2476) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (151, 221, 321) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 661) [M::mem_pestat] mean and std.dev: (246.03, 122.30) [M::mem_pestat] low and high boundaries for proper pairs: (1, 831) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (502, 1126, 3184) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8548) [M::mem_pestat] mean and std.dev: (1857.12, 1973.91) [M::mem_pestat] low and high boundaries for proper pairs: (1, 11230) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (184, 310, 898) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2326) [M::mem_pestat] mean and std.dev: (461.51, 419.11) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3040) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 702868 sequences (100000204 bp) in 2.413 CPU sec, 2.823 real sec... [M::process] read 702032 sequences (100000291 bp) in 1.909 CPU sec, 1.912 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 280837, 33, 73) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (199, 371, 1055) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2767) [M::mem_pestat] mean and std.dev: (556.27, 564.44) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3623) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (153, 225, 324) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 666) [M::mem_pestat] mean and std.dev: (248.65, 122.55) [M::mem_pestat] low and high boundaries for proper pairs: (1, 837) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (443, 514, 2310) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6044) [M::mem_pestat] mean and std.dev: (1112.47, 1364.02) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7911) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (233, 507, 1263) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3323) [M::mem_pestat] mean and std.dev: (719.52, 690.45) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4353) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 706090 reads in 206.495 CPU sec, 6.650 real sec sorting block 120, #reads = 1067065 mem = 536881359 peak = 1229017088 [M::mem_process_seqs] Processed 704366 reads in 145.373 CPU sec, 4.659 real sec [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 281035, 32, 50) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (171, 389, 1227) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3339) [M::mem_pestat] mean and std.dev: (648.76, 751.88) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4395) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (155, 230, 331) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 683) [M::mem_pestat] mean and std.dev: (253.36, 124.98) [M::mem_pestat] low and high boundaries for proper pairs: (1, 859) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (302, 846, 1229) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3083) [M::mem_pestat] mean and std.dev: (792.21, 612.35) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4010) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (249, 502, 908) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2226) [M::mem_pestat] mean and std.dev: (565.91, 456.54) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2885) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 701470 sequences (100000034 bp) in 2.481 CPU sec, 2.755 real sec... [M::process] read 700918 sequences (100000253 bp) in 1.843 CPU sec, 1.901 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 280594, 24, 47) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (177, 454, 1250) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3396) [M::mem_pestat] mean and std.dev: (907.08, 990.66) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4870) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (156, 231, 335) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 693) [M::mem_pestat] mean and std.dev: (255.59, 126.47) [M::mem_pestat] low and high boundaries for proper pairs: (1, 872) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (419, 819, 2479) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6599) [M::mem_pestat] mean and std.dev: (1073.95, 1138.01) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8659) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (227, 342, 458) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 920) [M::mem_pestat] mean and std.dev: (306.95, 147.40) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1151) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 702868 reads in 204.720 CPU sec, 6.585 real sec sorting block 121, #reads = 1065326 mem = 536878311 peak = 1229017088 [M::mem_process_seqs] Processed 702032 reads in 144.330 CPU sec, 4.643 real sec sorting block 122, #reads = 1065216 mem = 536880130 peak = 1229017088 [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 280285, 25, 46) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (180, 349, 582) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1386) [M::mem_pestat] mean and std.dev: (337.88, 230.78) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1788) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (157, 233, 335) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 691) [M::mem_pestat] mean and std.dev: (256.45, 126.06) [M::mem_pestat] low and high boundaries for proper pairs: (1, 869) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (754, 1644, 2176) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5020) [M::mem_pestat] mean and std.dev: (1418.76, 870.47) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6442) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (200, 372, 882) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2246) [M::mem_pestat] mean and std.dev: (483.26, 406.58) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2928) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 700938 sequences (100000042 bp) in 2.429 CPU sec, 2.689 real sec... [M::process] read 700546 sequences (100000234 bp) in 1.974 CPU sec, 2.034 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 280270, 30, 50) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (257, 414, 968) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2390) [M::mem_pestat] mean and std.dev: (619.40, 534.04) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3101) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (159, 234, 335) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 687) [M::mem_pestat] mean and std.dev: (257.00, 125.69) [M::mem_pestat] low and high boundaries for proper pairs: (1, 863) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (217, 785, 2606) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7384) [M::mem_pestat] mean and std.dev: (1253.66, 1436.20) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9773) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (238, 481, 749) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1771) [M::mem_pestat] mean and std.dev: (496.19, 335.33) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2282) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 701470 reads in 201.418 CPU sec, 6.497 real sec [M::mem_process_seqs] Processed 700918 reads in 139.032 CPU sec, 4.464 real sec sorting block 123, #reads = 1065678 mem = 536881295 peak = 1229017088 [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 280522, 21, 50) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (251, 397, 775) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1823) [M::mem_pestat] mean and std.dev: (441.02, 340.39) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2347) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (158, 233, 332) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 680) [M::mem_pestat] mean and std.dev: (254.73, 123.41) [M::mem_pestat] low and high boundaries for proper pairs: (1, 854) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (294, 353, 1175) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2937) [M::mem_pestat] mean and std.dev: (812.25, 737.19) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3818) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (168, 239, 710) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1794) [M::mem_pestat] mean and std.dev: (418.24, 402.36) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2336) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 700042 sequences (100000213 bp) in 2.299 CPU sec, 2.591 real sec... [M::process] read 699868 sequences (100000189 bp) in 1.760 CPU sec, 1.830 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 280391, 19, 45) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (205, 451, 903) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2299) [M::mem_pestat] mean and std.dev: (575.96, 528.06) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2997) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (159, 235, 336) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 690) [M::mem_pestat] mean and std.dev: (257.32, 125.39) [M::mem_pestat] low and high boundaries for proper pairs: (1, 867) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (432, 575, 1715) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4281) [M::mem_pestat] mean and std.dev: (1061.58, 917.52) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5564) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (231, 454, 766) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1836) [M::mem_pestat] mean and std.dev: (415.58, 308.40) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2371) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 700938 reads in 198.152 CPU sec, 6.377 real sec [M::mem_process_seqs] Processed 700546 reads in 135.690 CPU sec, 4.347 real sec sorting block 124, #reads = 1064517 mem = 536880632 peak = 1229017088 [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 279845, 14, 50) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (235, 334, 1042) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2656) [M::mem_pestat] mean and std.dev: (390.62, 321.63) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3463) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (160, 236, 337) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 691) [M::mem_pestat] mean and std.dev: (257.91, 125.31) [M::mem_pestat] low and high boundaries for proper pairs: (1, 868) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (359, 931, 1143) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2711) [M::mem_pestat] mean and std.dev: (771.00, 599.36) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3495) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (246, 472, 1123) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2877) [M::mem_pestat] mean and std.dev: (533.61, 425.90) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3754) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 699338 sequences (100000041 bp) in 2.447 CPU sec, 2.907 real sec... [M::process] read 699384 sequences (100000083 bp) in 1.623 CPU sec, 1.630 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 279791, 33, 51) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (166, 329, 599) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1465) [M::mem_pestat] mean and std.dev: (399.02, 323.03) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1898) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (160, 237, 341) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 703) [M::mem_pestat] mean and std.dev: (260.74, 128.62) [M::mem_pestat] low and high boundaries for proper pairs: (1, 884) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (227, 782, 1326) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3524) [M::mem_pestat] mean and std.dev: (921.52, 773.38) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4623) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (233, 355, 1066) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2732) [M::mem_pestat] mean and std.dev: (620.45, 615.65) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3565) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 700042 reads in 193.873 CPU sec, 6.244 real sec sorting block 125, #reads = 1065703 mem = 536880145 peak = 1229017088 [M::mem_process_seqs] Processed 699868 reads in 133.169 CPU sec, 4.271 real sec sorting block 126, #reads = 1066281 mem = 536880264 peak = 1229017088 [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 279430, 26, 62) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (156, 195, 495) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1173) [M::mem_pestat] mean and std.dev: (292.66, 241.91) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1512) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (160, 238, 342) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 706) [M::mem_pestat] mean and std.dev: (261.22, 128.31) [M::mem_pestat] low and high boundaries for proper pairs: (1, 888) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (810, 1191, 1873) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3999) [M::mem_pestat] mean and std.dev: (1271.12, 753.95) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5062) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (232, 446, 1200) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3136) [M::mem_pestat] mean and std.dev: (622.05, 548.03) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4104) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 547558 sequences (78190926 bp) in 2.125 CPU sec, 2.371 real sec... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 279800, 25, 52) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (279, 521, 1406) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3660) [M::mem_pestat] mean and std.dev: (898.15, 873.38) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4787) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (161, 239, 345) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 713) [M::mem_pestat] mean and std.dev: (262.93, 130.22) [M::mem_pestat] low and high boundaries for proper pairs: (1, 897) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (433, 949, 1290) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3004) [M::mem_pestat] mean and std.dev: (760.57, 407.50) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3861) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (197, 341, 901) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2309) [M::mem_pestat] mean and std.dev: (444.96, 319.55) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3013) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 699338 reads in 189.034 CPU sec, 6.152 real sec [M::mem_process_seqs] Processed 699384 reads in 130.691 CPU sec, 4.241 real sec sorting block 127, #reads = 1067304 mem = 536877909 peak = 1229017088 [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 218659, 19, 40) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (269, 362, 768) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1766) [M::mem_pestat] mean and std.dev: (433.17, 361.56) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2265) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (160, 237, 343) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 709) [M::mem_pestat] mean and std.dev: (261.19, 129.52) [M::mem_pestat] low and high boundaries for proper pairs: (1, 892) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (451, 869, 3300) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8998) [M::mem_pestat] mean and std.dev: (1559.00, 1752.59) [M::mem_pestat] low and high boundaries for proper pairs: (1, 11847) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (190, 375, 919) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2377) [M::mem_pestat] mean and std.dev: (488.21, 514.56) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3106) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 547558 reads in 91.383 CPU sec, 3.078 real sec sorting block 128, #reads = 1065005 mem = 536882809 peak = 1229017088 os version: Linux 6.12.88 cpu vendor: GenuineIntel signature: 000a06d1 features: 1f8bfbff fffab20b extended: f1bf27eb 1b407f7e amd bits: 2c100800 00000121 brand: Intel(R) Xeon(R) 6975P-C threads: 31 algo: bwa-mem license: sentieon:klib=31 reads: 136779168 overall: 70769553408 mem 22636.124 user 156.495 sys 753.193 real [main] Version: 0.7.17-r1188 [main] CMD: /opt/conda/share/sentieon-202308.03-3/libexec/bwa mem -K 100000000 -Y -R @RG\tID:A23MHWWLT4.1136_76X-T1-TDNA-1_A23MHWWLT4_1.L004\tPU:L004\tSM:1136_76X-T1-TDNA-1_A23MHWWLT4_1\tLB:1136_76X-T1-TDNA-1_A23MHWWLT4_1\tDS:s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta\tPL:ILLUMINA -t 31 ./BWAIndex/Homo_sapiens_assembly38.fasta.64 1136_76X-T1-TDNA-1_A23MHWWLT4_1_R1.fastq.gz 1136_76X-T1-TDNA-1_A23MHWWLT4_1_R2.fastq.gz [main] Real time: 753.228 sec; CPU: 22792.621 sec sorting block 129, #reads = 107550 mem = 54920091 peak = 1229017088 uniq header count 1 merging 130 blocks sw version: sentieon-genomics-202308.03 os version: Linux 6.12.88 cpu vendor: GenuineIntel signature: 000a06d1 features: 1f8bfbff fffab20b extended: f1bf27eb 1b407f7e amd bits: 2c100800 00000121 brand: Intel(R) Xeon(R) 6975P-C threads: 31 max 64 algo: util-sort license: sentieon:util=1 output file size: 7922261102 output reads: 137914991 bam_mem_sort: 130 calls 75.413 user 0.085 sys 79.228 real bam_write: 130 calls 78.568 user 3.697 sys 187.227 real execute: 1 calls 38.475 user 0.779 sys 802.362 real merge_files: 1 calls 38.448 user 0.760 sys 49.048 real parse_chunk: 2066 calls 89.740 user 21.885 sys 150.690 real read_chunk: 5595 calls 47.791 user 23.950 sys 710.625 real sort_block: 1 calls 30.414 user 23.418 sys 688.836 real write_chunk: 3527 calls 38.073 user 0.508 sys 48.072 real overall: 3698585600 mem 1928.079 user 59.661 sys 802.380 real ls: cannot access '*.cram': No such file or directory