.command.log - Workdir - DAQ:SENTIEON_BWAMEM (1136_76X-T1-TDNA-1_A23MHWWLT4_1;L004;0001)

File Info

Filename: .command.log
Full Path: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/fb/eba02307739035dc473c7fe028a96e/.command.log
Size: 332.8 KB
Task: DAQ:SENTIEON_BWAMEM (1136_76X-T1-TDNA-1_A23MHWWLT4_1;L004;0001)
Attempt
Content

  Downloading: s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/fb/eba02307739035dc473c7fe028a96e/.command.sh
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/52/5fec2e5117035353c5535f2ccffc87/1136_76X-T1-TDNA-1_A23MHWWLT4_1/1136_76X-T1-TDNA-1_A23MHWWLT4_1_R1.fastq.gz
  Downloading: s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta.fai
  Downloading: s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/BWAIndex
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/fb/eba02307739035dc473c7fe028a96e/.command.run
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/52/5fec2e5117035353c5535f2ccffc87/1136_76X-T1-TDNA-1_A23MHWWLT4_1/1136_76X-T1-TDNA-1_A23MHWWLT4_1_R2.fastq.gz
==> STAGING COMPLETE (7 inputs)

This software is licensed to bgold@natera.com by Sentieon Inc.
cmdline: /opt/conda/share/sentieon-202308.03-3/libexec/util sort -r Homo_sapiens_assembly38.fasta -t 31 -o 1136_76X-T1-TDNA-1_A23MHWWLT4_1.bam --sam2bam -
This software is licensed to bgold@natera.com by Sentieon Inc.
version: sentieon-genomics-202308.03
[M::bwa_idx_load_from_disk] read 3171 ALT contigs
[M::main_mem] bwa index loaded in 1707.476 CPU sec, 57.911 real sec
[M::process] read 704404 sequences (100000190 bp) in 0.910 CPU sec, 0.919 real sec...
[M::process] read 703362 sequences (100000089 bp) in 1.450 CPU sec, 1.441 real sec...
[M::process] read 703866 sequences (100000272 bp) in 1.505 CPU sec, 1.514 real sec...
[M::process] read 702904 sequences (100000252 bp) in 1.522 CPU sec, 1.529 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 281029, 37, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (233, 310, 1173)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3053)
[M::mem_pestat] mean and std.dev: (506.77, 641.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3993)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 229, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 682)
[M::mem_pestat] mean and std.dev: (251.83, 124.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 858)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 546, 2121)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6047)
[M::mem_pestat] mean and std.dev: (1067.71, 1186.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8010)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 214, 1345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3699)
[M::mem_pestat] mean and std.dev: (635.83, 751.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4876)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703362 reads in 106.039 CPU sec, 3.355 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 281005, 17, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 241, 493)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1127)
[M::mem_pestat] mean and std.dev: (293.47, 179.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1444)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 228, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 676)
[M::mem_pestat] mean and std.dev: (250.51, 123.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 850)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (317, 828, 1430)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3656)
[M::mem_pestat] mean and std.dev: (735.80, 683.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4769)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 417, 850)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2168)
[M::mem_pestat] mean and std.dev: (485.36, 373.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2827)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701924 sequences (100000087 bp) in 1.673 CPU sec, 1.690 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 281066, 21, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 356, 649)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1515)
[M::mem_pestat] mean and std.dev: (380.66, 272.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1948)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 229, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 683)
[M::mem_pestat] mean and std.dev: (252.56, 125.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 859)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (806, 1118, 2732)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6584)
[M::mem_pestat] mean and std.dev: (1645.86, 1123.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8510)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (255, 462, 1214)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3132)
[M::mem_pestat] mean and std.dev: (897.37, 894.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4474)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704404 reads in 278.098 CPU sec, 8.811 real sec
sorting block 0, #reads = 1071723 mem = 536882168 peak = 635039744
[M::mem_process_seqs] Processed 703866 reads in 150.487 CPU sec, 4.869 real sec
[M::process] read 701484 sequences (100000287 bp) in 1.900 CPU sec, 2.254 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 281217, 28, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (130, 266, 742)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1966)
[M::mem_pestat] mean and std.dev: (375.94, 282.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2578)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 230, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 689)
[M::mem_pestat] mean and std.dev: (254.10, 125.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 867)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (368, 1175, 2265)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6059)
[M::mem_pestat] mean and std.dev: (1262.71, 973.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7956)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 353, 658)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1546)
[M::mem_pestat] mean and std.dev: (439.38, 343.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1990)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700956 sequences (100000253 bp) in 1.623 CPU sec, 1.625 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 280892, 32, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (230, 339, 877)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2171)
[M::mem_pestat] mean and std.dev: (478.82, 367.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2818)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 232, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 697)
[M::mem_pestat] mean and std.dev: (256.58, 127.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 877)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (437, 977, 1506)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3644)
[M::mem_pestat] mean and std.dev: (999.03, 727.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4713)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (293, 454, 1132)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2810)
[M::mem_pestat] mean and std.dev: (672.44, 575.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3649)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 280768, 14, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 364, 710)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1686)
[M::mem_pestat] mean and std.dev: (420.47, 297.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2174)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 235, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 701)
[M::mem_pestat] mean and std.dev: (258.28, 127.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 882)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 920, 1460)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4080)
[M::mem_pestat] mean and std.dev: (807.15, 761.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5390)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 293, 1009)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2705)
[M::mem_pestat] mean and std.dev: (481.07, 514.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3553)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702904 reads in 260.333 CPU sec, 8.406 real sec
sorting block 1, #reads = 1070269 mem = 536877185 peak = 929181696
[M::mem_process_seqs] Processed 701924 reads in 203.270 CPU sec, 6.540 real sec
[M::mem_process_seqs] Processed 701484 reads in 228.585 CPU sec, 7.385 real sec
sorting block 2, #reads = 1070563 mem = 536879560 peak = 972099584
[M::process] read 701040 sequences (100000084 bp) in 2.053 CPU sec, 2.361 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 280469, 19, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 396, 1705)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4725)
[M::mem_pestat] mean and std.dev: (760.41, 787.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6235)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 236, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 707)
[M::mem_pestat] mean and std.dev: (260.09, 129.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 890)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (107, 1329, 2916)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8534)
[M::mem_pestat] mean and std.dev: (2010.21, 2152.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11343)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (263, 702, 1051)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2627)
[M::mem_pestat] mean and std.dev: (717.32, 564.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3415)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700760 sequences (100000262 bp) in 2.044 CPU sec, 2.315 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 280226, 22, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 687, 1730)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4894)
[M::mem_pestat] mean and std.dev: (860.03, 837.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6476)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 236, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 711)
[M::mem_pestat] mean and std.dev: (260.96, 130.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 895)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (394, 1153, 3425)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9487)
[M::mem_pestat] mean and std.dev: (2124.32, 2178.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12518)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 305, 446)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1014)
[M::mem_pestat] mean and std.dev: (287.98, 161.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1298)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700348 sequences (100000058 bp) in 1.640 CPU sec, 1.647 real sec...
[M::mem_process_seqs] Processed 700956 reads in 184.523 CPU sec, 5.999 real sec
sorting block 3, #reads = 1069638 mem = 536877563 peak = 972099584
[M::mem_process_seqs] Processed 701040 reads in 128.215 CPU sec, 4.145 real sec
sorting block 4, #reads = 1070698 mem = 536879151 peak = 972099584
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 280329, 24, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (297, 697, 1634)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4308)
[M::mem_pestat] mean and std.dev: (996.10, 848.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5645)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 236, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 714)
[M::mem_pestat] mean and std.dev: (261.69, 130.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 899)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (305, 587, 1855)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4955)
[M::mem_pestat] mean and std.dev: (1018.82, 1350.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6505)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (230, 559, 1215)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3185)
[M::mem_pestat] mean and std.dev: (700.44, 541.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4170)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699810 sequences (100000033 bp) in 2.106 CPU sec, 2.333 real sec...
[M::process] read 699922 sequences (100000252 bp) in 1.660 CPU sec, 1.740 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 280484, 18, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 257, 929)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2395)
[M::mem_pestat] mean and std.dev: (393.65, 370.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3128)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 238, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 712)
[M::mem_pestat] mean and std.dev: (262.22, 130.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 896)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 728, 1319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3513)
[M::mem_pestat] mean and std.dev: (796.59, 752.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4610)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 306, 689)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1693)
[M::mem_pestat] mean and std.dev: (377.77, 345.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2195)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700760 reads in 180.753 CPU sec, 6.039 real sec
[M::mem_process_seqs] Processed 700348 reads in 126.380 CPU sec, 4.170 real sec
sorting block 5, #reads = 1069638 mem = 536877741 peak = 972099584
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 279717, 30, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 454, 1145)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3029)
[M::mem_pestat] mean and std.dev: (695.35, 625.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3971)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 238, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 712)
[M::mem_pestat] mean and std.dev: (262.44, 130.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 896)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (859, 2355, 2908)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7006)
[M::mem_pestat] mean and std.dev: (1970.69, 1302.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9055)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 764, 2000)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5564)
[M::mem_pestat] mean and std.dev: (1259.74, 1407.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7346)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699472 sequences (100000151 bp) in 2.121 CPU sec, 2.300 real sec...
[M::process] read 700032 sequences (100000012 bp) in 1.719 CPU sec, 1.736 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 279512, 30, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 395, 1143)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3079)
[M::mem_pestat] mean and std.dev: (581.14, 551.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4047)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 237, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 703)
[M::mem_pestat] mean and std.dev: (260.84, 128.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 884)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (265, 762, 1914)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5212)
[M::mem_pestat] mean and std.dev: (827.04, 713.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6861)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (238, 385, 721)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1687)
[M::mem_pestat] mean and std.dev: (387.95, 284.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2170)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699810 reads in 185.981 CPU sec, 6.076 real sec
sorting block 6, #reads = 1069469 mem = 536886500 peak = 972099584
[M::mem_process_seqs] Processed 699922 reads in 128.930 CPU sec, 4.148 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 279847, 31, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 548, 1306)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3512)
[M::mem_pestat] mean and std.dev: (676.24, 615.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4615)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 239, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 707)
[M::mem_pestat] mean and std.dev: (262.06, 129.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 889)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (449, 1144, 1522)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3668)
[M::mem_pestat] mean and std.dev: (1110.00, 819.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4741)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 381, 573)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1277)
[M::mem_pestat] mean and std.dev: (368.77, 225.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1629)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700114 sequences (100000287 bp) in 2.247 CPU sec, 2.657 real sec...
[M::process] read 700194 sequences (100000119 bp) in 1.652 CPU sec, 1.670 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 279923, 32, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (255, 839, 1191)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3063)
[M::mem_pestat] mean and std.dev: (770.92, 630.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3999)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 236, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 705)
[M::mem_pestat] mean and std.dev: (260.75, 129.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 887)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (232, 665, 1003)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2545)
[M::mem_pestat] mean and std.dev: (580.79, 444.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3316)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 534, 1389)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3755)
[M::mem_pestat] mean and std.dev: (832.46, 818.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4938)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699472 reads in 180.696 CPU sec, 5.855 real sec
sorting block 7, #reads = 1068305 mem = 536881643 peak = 972099584
[M::mem_process_seqs] Processed 700032 reads in 126.411 CPU sec, 4.295 real sec
sorting block 8, #reads = 1068659 mem = 536883353 peak = 972099584
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 279776, 36, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 417, 1289)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3459)
[M::mem_pestat] mean and std.dev: (797.31, 753.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4544)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 236, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 700)
[M::mem_pestat] mean and std.dev: (260.03, 128.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 880)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (246, 932, 1839)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5025)
[M::mem_pestat] mean and std.dev: (1193.38, 1120.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6618)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (306, 752, 3001)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8391)
[M::mem_pestat] mean and std.dev: (2359.37, 2972.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14250)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699408 sequences (100000146 bp) in 2.198 CPU sec, 2.427 real sec...
[M::process] read 699268 sequences (100000111 bp) in 1.791 CPU sec, 1.798 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 279776, 16, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 297, 1243)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3417)
[M::mem_pestat] mean and std.dev: (560.05, 743.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4504)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 236, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 702)
[M::mem_pestat] mean and std.dev: (260.07, 128.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 883)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 531, 2361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6695)
[M::mem_pestat] mean and std.dev: (1042.67, 1268.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8862)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 395, 942)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2406)
[M::mem_pestat] mean and std.dev: (488.28, 370.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3138)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700114 reads in 186.726 CPU sec, 6.220 real sec
[M::mem_process_seqs] Processed 700194 reads in 128.698 CPU sec, 4.145 real sec
sorting block 9, #reads = 1069553 mem = 536881844 peak = 972099584
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 280013, 28, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 513, 1563)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4285)
[M::mem_pestat] mean and std.dev: (913.57, 853.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5646)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 238, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 707)
[M::mem_pestat] mean and std.dev: (261.87, 129.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 889)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (789, 1143, 2316)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5370)
[M::mem_pestat] mean and std.dev: (1625.25, 1165.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6897)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 324, 699)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1661)
[M::mem_pestat] mean and std.dev: (429.94, 351.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2142)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698986 sequences (100000287 bp) in 2.377 CPU sec, 2.590 real sec...
[M::process] read 698346 sequences (100000058 bp) in 1.788 CPU sec, 1.798 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 279647, 29, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 308, 739)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1915)
[M::mem_pestat] mean and std.dev: (412.72, 415.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2503)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 239, 345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 715)
[M::mem_pestat] mean and std.dev: (263.16, 130.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 900)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (288, 685, 1405)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3639)
[M::mem_pestat] mean and std.dev: (644.80, 517.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4756)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 500, 1266)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3442)
[M::mem_pestat] mean and std.dev: (865.27, 911.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4530)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699408 reads in 186.046 CPU sec, 6.078 real sec
[M::mem_process_seqs] Processed 699268 reads in 127.667 CPU sec, 4.201 real sec
sorting block 10, #reads = 1068636 mem = 536878934 peak = 975253504
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 279425, 27, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 492, 1046)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2756)
[M::mem_pestat] mean and std.dev: (585.58, 611.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3611)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 240, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 710)
[M::mem_pestat] mean and std.dev: (262.80, 129.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 893)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (314, 565, 2877)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8003)
[M::mem_pestat] mean and std.dev: (1361.62, 1440.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10566)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (250, 386, 1002)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2506)
[M::mem_pestat] mean and std.dev: (557.09, 526.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3258)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698372 sequences (100000288 bp) in 2.122 CPU sec, 2.486 real sec...
[M::process] read 697926 sequences (100000261 bp) in 1.892 CPU sec, 1.897 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 279332, 42, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 290, 785)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2033)
[M::mem_pestat] mean and std.dev: (504.38, 479.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2657)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 242, 347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 715)
[M::mem_pestat] mean and std.dev: (264.86, 130.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 899)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (386, 1114, 3500)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9728)
[M::mem_pestat] mean and std.dev: (2193.33, 2812.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13443)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (272, 406, 1068)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2660)
[M::mem_pestat] mean and std.dev: (588.43, 450.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3456)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698986 reads in 185.667 CPU sec, 6.095 real sec
sorting block 11, #reads = 1068236 mem = 536878780 peak = 975253504
[M::mem_process_seqs] Processed 698346 reads in 127.365 CPU sec, 4.104 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 278931, 20, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 262, 502)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1152)
[M::mem_pestat] mean and std.dev: (269.07, 147.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1477)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 242, 348)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 718)
[M::mem_pestat] mean and std.dev: (265.41, 130.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 903)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (626, 989, 1311)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2681)
[M::mem_pestat] mean and std.dev: (844.28, 515.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3366)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 325, 1227)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3231)
[M::mem_pestat] mean and std.dev: (623.24, 649.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4233)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 12, #reads = 1068623 mem = 536877586 peak = 1009647616
[M::process] read 698226 sequences (100000067 bp) in 2.292 CPU sec, 2.734 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 279232, 23, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 449, 1008)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2616)
[M::mem_pestat] mean and std.dev: (594.30, 544.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3420)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 243, 348)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 718)
[M::mem_pestat] mean and std.dev: (266.04, 130.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 903)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (357, 493, 1670)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4296)
[M::mem_pestat] mean and std.dev: (971.55, 1034.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5609)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (235, 545, 1099)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2827)
[M::mem_pestat] mean and std.dev: (590.08, 530.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3691)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697664 sequences (100000265 bp) in 1.579 CPU sec, 1.622 real sec...
[M::mem_process_seqs] Processed 698372 reads in 186.078 CPU sec, 6.134 real sec
[M::mem_process_seqs] Processed 697926 reads in 126.833 CPU sec, 4.109 real sec
sorting block 13, #reads = 1067433 mem = 536879577 peak = 1009647616
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 279174, 29, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 524, 2922)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8374)
[M::mem_pestat] mean and std.dev: (1373.55, 2035.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11100)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 243, 350)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 724)
[M::mem_pestat] mean and std.dev: (266.55, 131.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 911)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 760, 1761)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4899)
[M::mem_pestat] mean and std.dev: (983.14, 929.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6468)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (257, 496, 1297)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3377)
[M::mem_pestat] mean and std.dev: (657.69, 609.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4417)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697426 sequences (100000094 bp) in 2.177 CPU sec, 2.773 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 279024, 15, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (304, 932, 1671)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4405)
[M::mem_pestat] mean and std.dev: (871.12, 810.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5772)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 245, 353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 731)
[M::mem_pestat] mean and std.dev: (268.83, 132.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 920)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (739, 1158, 4289)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 11389)
[M::mem_pestat] mean and std.dev: (2093.33, 1889.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14939)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (233, 503, 828)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2018)
[M::mem_pestat] mean and std.dev: (549.15, 370.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2613)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703204 sequences (100000262 bp) in 1.795 CPU sec, 1.797 real sec...
[M::mem_process_seqs] Processed 698226 reads in 183.909 CPU sec, 5.988 real sec
[M::mem_process_seqs] Processed 697664 reads in 125.874 CPU sec, 4.148 real sec
sorting block 14, #reads = 1067869 mem = 536878486 peak = 1009647616
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 279350, 34, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 365, 922)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2454)
[M::mem_pestat] mean and std.dev: (428.03, 469.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3220)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 246, 355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 735)
[M::mem_pestat] mean and std.dev: (269.69, 132.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 925)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 456, 2607)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7487)
[M::mem_pestat] mean and std.dev: (1294.82, 1338.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9927)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 359, 2006)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5580)
[M::mem_pestat] mean and std.dev: (1032.22, 1327.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7367)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704328 sequences (100000199 bp) in 2.400 CPU sec, 2.906 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 280881, 26, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 222, 639)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1615)
[M::mem_pestat] mean and std.dev: (273.14, 221.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2103)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 230, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 689)
[M::mem_pestat] mean and std.dev: (254.23, 126.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 867)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (366, 954, 2236)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5976)
[M::mem_pestat] mean and std.dev: (1250.42, 1153.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7846)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 289, 633)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1543)
[M::mem_pestat] mean and std.dev: (342.66, 279.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1998)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703876 sequences (100000101 bp) in 1.664 CPU sec, 1.670 real sec...
[M::mem_process_seqs] Processed 697426 reads in 188.593 CPU sec, 6.205 real sec
sorting block 15, #reads = 1067584 mem = 536879973 peak = 1009647616
[M::mem_process_seqs] Processed 703204 reads in 132.956 CPU sec, 4.267 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 281717, 23, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 328, 876)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2288)
[M::mem_pestat] mean and std.dev: (469.61, 402.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2994)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 228, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 685)
[M::mem_pestat] mean and std.dev: (252.67, 126.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 862)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (495, 978, 1118)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2364)
[M::mem_pestat] mean and std.dev: (880.18, 595.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3264)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 515, 1462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4024)
[M::mem_pestat] mean and std.dev: (714.55, 605.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5305)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 16, #reads = 1067333 mem = 536882731 peak = 1017102336
[M::process] read 703294 sequences (100000101 bp) in 2.376 CPU sec, 2.744 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 281062, 25, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (247, 509, 1606)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4324)
[M::mem_pestat] mean and std.dev: (855.18, 724.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5683)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 229, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 691)
[M::mem_pestat] mean and std.dev: (253.98, 127.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 870)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 566, 2195)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6171)
[M::mem_pestat] mean and std.dev: (919.83, 1202.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8159)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (283, 510, 1245)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3169)
[M::mem_pestat] mean and std.dev: (713.50, 549.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4131)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702492 sequences (100000187 bp) in 1.802 CPU sec, 1.817 real sec...
[M::mem_process_seqs] Processed 704328 reads in 179.666 CPU sec, 5.823 real sec
[M::mem_process_seqs] Processed 703876 reads in 125.987 CPU sec, 4.128 real sec
sorting block 17, #reads = 1073684 mem = 536880483 peak = 1017102336
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 281206, 22, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (283, 769, 1431)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3727)
[M::mem_pestat] mean and std.dev: (692.38, 519.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4875)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 231, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 695)
[M::mem_pestat] mean and std.dev: (255.24, 127.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 875)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (242, 946, 1584)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4268)
[M::mem_pestat] mean and std.dev: (1104.90, 997.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5610)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 394, 1563)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4305)
[M::mem_pestat] mean and std.dev: (840.76, 1029.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5676)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702346 sequences (100000103 bp) in 2.241 CPU sec, 2.787 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 281384, 22, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 219, 972)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2574)
[M::mem_pestat] mean and std.dev: (495.54, 574.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3375)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 231, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 699)
[M::mem_pestat] mean and std.dev: (256.55, 128.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 880)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (300, 881, 2517)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6951)
[M::mem_pestat] mean and std.dev: (1424.86, 1442.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9168)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 269, 669)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1689)
[M::mem_pestat] mean and std.dev: (302.06, 203.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2199)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701578 sequences (100000139 bp) in 1.670 CPU sec, 1.688 real sec...
[M::mem_process_seqs] Processed 703294 reads in 183.735 CPU sec, 6.026 real sec
[M::mem_process_seqs] Processed 702492 reads in 124.933 CPU sec, 4.132 real sec
sorting block 18, #reads = 1072989 mem = 536890539 peak = 1017102336
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 281056, 25, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (272, 372, 1949)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5303)
[M::mem_pestat] mean and std.dev: (894.33, 1022.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6980)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 232, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 702)
[M::mem_pestat] mean and std.dev: (257.29, 128.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 884)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (287, 473, 1374)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3548)
[M::mem_pestat] mean and std.dev: (762.61, 752.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4635)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (288, 756, 969)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2331)
[M::mem_pestat] mean and std.dev: (637.19, 443.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3012)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701390 sequences (100000029 bp) in 2.297 CPU sec, 2.753 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 281053, 30, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 571, 1282)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3514)
[M::mem_pestat] mean and std.dev: (649.98, 630.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4630)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 236, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 713)
[M::mem_pestat] mean and std.dev: (260.79, 130.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 898)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (141, 218, 2243)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6447)
[M::mem_pestat] mean and std.dev: (1057.96, 1488.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8549)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (249, 380, 1235)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3207)
[M::mem_pestat] mean and std.dev: (609.81, 560.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4193)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701116 sequences (100000026 bp) in 1.798 CPU sec, 1.872 real sec...
[M::mem_process_seqs] Processed 702346 reads in 182.777 CPU sec, 6.017 real sec
sorting block 19, #reads = 1071102 mem = 536880125 peak = 1017102336
[M::mem_process_seqs] Processed 701578 reads in 124.038 CPU sec, 4.045 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 280628, 41, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 330, 623)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1491)
[M::mem_pestat] mean and std.dev: (488.56, 413.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2142)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 236, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 713)
[M::mem_pestat] mean and std.dev: (260.98, 130.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 898)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (280, 318, 1071)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2653)
[M::mem_pestat] mean and std.dev: (590.46, 611.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3444)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 388, 965)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2525)
[M::mem_pestat] mean and std.dev: (570.07, 565.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3305)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 20, #reads = 1071840 mem = 536877763 peak = 1017102336
[M::process] read 701250 sequences (100000151 bp) in 2.443 CPU sec, 2.743 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 280959, 34, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (292, 438, 881)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2059)
[M::mem_pestat] mean and std.dev: (626.39, 496.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2648)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 237, 345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 719)
[M::mem_pestat] mean and std.dev: (262.16, 131.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 906)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (367, 562, 1274)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3088)
[M::mem_pestat] mean and std.dev: (783.91, 624.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3995)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 350, 1330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3642)
[M::mem_pestat] mean and std.dev: (847.08, 1052.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5059)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700912 sequences (100000098 bp) in 1.692 CPU sec, 1.745 real sec...
[M::mem_process_seqs] Processed 701390 reads in 184.393 CPU sec, 6.017 real sec
[M::mem_process_seqs] Processed 701116 reads in 125.658 CPU sec, 4.066 real sec
sorting block 21, #reads = 1072298 mem = 536881699 peak = 1017102336
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 280204, 26, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 414, 1720)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4846)
[M::mem_pestat] mean and std.dev: (870.27, 884.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6409)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 236, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 716)
[M::mem_pestat] mean and std.dev: (261.55, 131.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 902)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (411, 1314, 2497)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6669)
[M::mem_pestat] mean and std.dev: (1524.80, 1387.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8755)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (266, 471, 1294)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3350)
[M::mem_pestat] mean and std.dev: (722.61, 593.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4378)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700800 sequences (100000095 bp) in 2.484 CPU sec, 2.880 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 280323, 27, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 387, 969)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2509)
[M::mem_pestat] mean and std.dev: (514.05, 515.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3279)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 237, 346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 720)
[M::mem_pestat] mean and std.dev: (262.50, 131.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 907)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (232, 686, 1062)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2722)
[M::mem_pestat] mean and std.dev: (693.30, 571.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3552)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 353, 888)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2234)
[M::mem_pestat] mean and std.dev: (518.28, 516.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2907)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700766 sequences (100000048 bp) in 1.790 CPU sec, 1.984 real sec...
[M::mem_process_seqs] Processed 701250 reads in 181.657 CPU sec, 5.907 real sec
[M::mem_process_seqs] Processed 700912 reads in 126.796 CPU sec, 4.375 real sec
sorting block 22, #reads = 1070461 mem = 536882735 peak = 1017102336
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 280653, 33, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (145, 284, 703)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1819)
[M::mem_pestat] mean and std.dev: (395.43, 352.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2377)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 236, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 716)
[M::mem_pestat] mean and std.dev: (261.46, 131.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 902)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (250, 772, 1860)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5080)
[M::mem_pestat] mean and std.dev: (1195.33, 1157.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6690)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (256, 407, 967)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2389)
[M::mem_pestat] mean and std.dev: (528.42, 451.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3100)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700294 sequences (100000094 bp) in 2.429 CPU sec, 2.835 real sec...
[M::process] read 700614 sequences (100000262 bp) in 1.625 CPU sec, 1.628 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 280424, 29, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (249, 516, 1377)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3633)
[M::mem_pestat] mean and std.dev: (861.97, 764.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4761)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 236, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 711)
[M::mem_pestat] mean and std.dev: (261.41, 130.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 895)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (370, 892, 1061)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2443)
[M::mem_pestat] mean and std.dev: (732.85, 443.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3134)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (238, 470, 1732)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4720)
[M::mem_pestat] mean and std.dev: (895.61, 904.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6214)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700800 reads in 188.002 CPU sec, 6.321 real sec
sorting block 23, #reads = 1069554 mem = 536877354 peak = 1017102336
[M::mem_process_seqs] Processed 700766 reads in 129.162 CPU sec, 4.229 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 279704, 24, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (253, 364, 514)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1036)
[M::mem_pestat] mean and std.dev: (305.96, 134.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1297)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 236, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 705)
[M::mem_pestat] mean and std.dev: (260.12, 128.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 887)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (132, 341, 914)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2478)
[M::mem_pestat] mean and std.dev: (624.46, 691.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3388)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 305, 1188)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3154)
[M::mem_pestat] mean and std.dev: (583.20, 568.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4137)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 24, #reads = 1068592 mem = 536879043 peak = 1065345024
[M::process] read 700400 sequences (100000015 bp) in 2.376 CPU sec, 2.909 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 280229, 26, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (275, 397, 1229)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3137)
[M::mem_pestat] mean and std.dev: (651.27, 671.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4091)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 235, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 702)
[M::mem_pestat] mean and std.dev: (259.30, 127.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 883)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (749, 1337, 3378)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8636)
[M::mem_pestat] mean and std.dev: (1856.62, 1568.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11265)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 275, 718)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1804)
[M::mem_pestat] mean and std.dev: (327.19, 248.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2347)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700360 sequences (100000048 bp) in 1.846 CPU sec, 1.850 real sec...
[M::mem_process_seqs] Processed 700294 reads in 185.947 CPU sec, 6.134 real sec
[M::mem_process_seqs] Processed 700614 reads in 130.043 CPU sec, 4.180 real sec
sorting block 25, #reads = 1070060 mem = 536883218 peak = 1065345024
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 279860, 26, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 311, 2632)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7484)
[M::mem_pestat] mean and std.dev: (1327.07, 1589.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9910)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 235, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 699)
[M::mem_pestat] mean and std.dev: (258.90, 127.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 879)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (363, 1158, 3944)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 11106)
[M::mem_pestat] mean and std.dev: (2129.15, 2204.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14687)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 353, 1075)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2811)
[M::mem_pestat] mean and std.dev: (662.86, 654.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3679)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699532 sequences (100000200 bp) in 2.465 CPU sec, 2.698 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 279957, 32, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 283, 1388)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3838)
[M::mem_pestat] mean and std.dev: (615.48, 680.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5063)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 236, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 702)
[M::mem_pestat] mean and std.dev: (259.31, 127.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 883)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (763, 1533, 2069)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4681)
[M::mem_pestat] mean and std.dev: (1405.67, 879.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5987)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 350, 867)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2231)
[M::mem_pestat] mean and std.dev: (529.88, 443.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2913)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699492 sequences (100000052 bp) in 1.674 CPU sec, 1.715 real sec...
[M::mem_process_seqs] Processed 700400 reads in 184.349 CPU sec, 5.938 real sec
[M::mem_process_seqs] Processed 700360 reads in 130.192 CPU sec, 4.250 real sec
sorting block 26, #reads = 1069084 mem = 536878733 peak = 1065345024
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 279884, 22, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 372, 915)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2371)
[M::mem_pestat] mean and std.dev: (478.95, 367.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3099)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 238, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 704)
[M::mem_pestat] mean and std.dev: (261.10, 128.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 885)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (269, 721, 1474)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3884)
[M::mem_pestat] mean and std.dev: (827.16, 795.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5089)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (287, 491, 1418)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3680)
[M::mem_pestat] mean and std.dev: (662.18, 570.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4811)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699508 sequences (100000016 bp) in 2.319 CPU sec, 2.603 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 279486, 39, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 503, 968)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2522)
[M::mem_pestat] mean and std.dev: (563.58, 553.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3299)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 237, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 703)
[M::mem_pestat] mean and std.dev: (260.84, 128.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 884)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (521, 840, 1358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3032)
[M::mem_pestat] mean and std.dev: (768.83, 506.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3869)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (236, 393, 726)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1706)
[M::mem_pestat] mean and std.dev: (503.53, 377.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2196)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699160 sequences (100000281 bp) in 1.925 CPU sec, 2.025 real sec...
[M::mem_process_seqs] Processed 699532 reads in 188.349 CPU sec, 6.134 real sec
sorting block 27, #reads = 1067904 mem = 536879106 peak = 1065345024
[M::mem_process_seqs] Processed 699492 reads in 130.195 CPU sec, 4.209 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 279411, 28, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 318, 498)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1126)
[M::mem_pestat] mean and std.dev: (268.11, 112.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1440)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 239, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 707)
[M::mem_pestat] mean and std.dev: (261.75, 128.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 889)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (694, 994, 1373)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2731)
[M::mem_pestat] mean and std.dev: (903.28, 399.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3410)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 393, 1414)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3806)
[M::mem_pestat] mean and std.dev: (790.85, 906.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5002)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699228 sequences (100000211 bp) in 2.430 CPU sec, 2.792 real sec...
sorting block 28, #reads = 1067159 mem = 536880513 peak = 1083846656
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 279846, 39, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 376, 1456)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4040)
[M::mem_pestat] mean and std.dev: (808.29, 871.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5332)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 239, 346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 716)
[M::mem_pestat] mean and std.dev: (263.86, 130.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 901)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (531, 1240, 1894)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4620)
[M::mem_pestat] mean and std.dev: (1414.31, 1220.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6295)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 250, 895)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2315)
[M::mem_pestat] mean and std.dev: (491.88, 594.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3025)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698702 sequences (100000264 bp) in 1.664 CPU sec, 2.011 real sec...
[M::mem_process_seqs] Processed 699508 reads in 188.403 CPU sec, 6.169 real sec
[M::mem_process_seqs] Processed 699160 reads in 127.078 CPU sec, 4.216 real sec
sorting block 29, #reads = 1067247 mem = 536878190 peak = 1083846656
[M::process] read 698880 sequences (100000253 bp) in 2.279 CPU sec, 2.693 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 280112, 25, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 339, 578)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1344)
[M::mem_pestat] mean and std.dev: (400.52, 254.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1727)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 241, 347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 717)
[M::mem_pestat] mean and std.dev: (264.48, 130.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 902)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (274, 603, 2408)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6676)
[M::mem_pestat] mean and std.dev: (1343.80, 1429.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8810)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 328, 550)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1342)
[M::mem_pestat] mean and std.dev: (324.05, 230.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1738)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699518 sequences (100000052 bp) in 1.829 CPU sec, 1.864 real sec...
[M::mem_process_seqs] Processed 698702 reads in 107.961 CPU sec, 3.473 real sec
sorting block 30, #reads = 1067845 mem = 536889920 peak = 1083846656
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 279330, 22, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (252, 528, 1863)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5085)
[M::mem_pestat] mean and std.dev: (1090.25, 1036.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6696)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 240, 346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 716)
[M::mem_pestat] mean and std.dev: (263.55, 130.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 901)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 860, 1962)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5566)
[M::mem_pestat] mean and std.dev: (986.38, 1101.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7368)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 484, 1418)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3844)
[M::mem_pestat] mean and std.dev: (737.83, 733.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5057)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 279526, 26, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (223, 461, 1644)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4486)
[M::mem_pestat] mean and std.dev: (1111.44, 1225.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6014)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 241, 348)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 720)
[M::mem_pestat] mean and std.dev: (264.65, 131.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 906)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (266, 594, 1802)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4874)
[M::mem_pestat] mean and std.dev: (1094.48, 1145.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6410)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 369, 954)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2490)
[M::mem_pestat] mean and std.dev: (549.64, 487.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3258)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699228 reads in 289.118 CPU sec, 9.456 real sec
[M::process] read 702648 sequences (100000130 bp) in 1.803 CPU sec, 1.958 real sec...
[M::mem_process_seqs] Processed 698880 reads in 161.567 CPU sec, 5.254 real sec
sorting block 31, #reads = 1067412 mem = 536880286 peak = 1083846656
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 280205, 16, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 373, 748)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1854)
[M::mem_pestat] mean and std.dev: (472.37, 373.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2407)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 240, 348)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 722)
[M::mem_pestat] mean and std.dev: (264.56, 132.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 909)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (775, 1734, 2581)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6193)
[M::mem_pestat] mean and std.dev: (1650.27, 1197.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7999)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (255, 346, 1226)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3168)
[M::mem_pestat] mean and std.dev: (640.97, 532.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4139)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705984 sequences (100000299 bp) in 2.524 CPU sec, 2.836 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 280982, 22, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (251, 362, 1691)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4571)
[M::mem_pestat] mean and std.dev: (858.32, 973.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6011)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 232, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 705)
[M::mem_pestat] mean and std.dev: (257.48, 129.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 888)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (327, 1180, 2638)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7260)
[M::mem_pestat] mean and std.dev: (1876.91, 1911.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9571)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 460, 526)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1252)
[M::mem_pestat] mean and std.dev: (341.40, 200.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1615)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705496 sequences (100000257 bp) in 1.630 CPU sec, 1.721 real sec...
[M::mem_process_seqs] Processed 699518 reads in 187.664 CPU sec, 6.053 real sec
[M::mem_process_seqs] Processed 702648 reads in 130.872 CPU sec, 4.203 real sec
sorting block 32, #reads = 1068337 mem = 536881310 peak = 1083846656
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 282212, 21, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (326, 544, 1800)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4748)
[M::mem_pestat] mean and std.dev: (1064.00, 1085.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6222)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 225, 327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 677)
[M::mem_pestat] mean and std.dev: (249.17, 124.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 852)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (803, 1816, 2203)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5003)
[M::mem_pestat] mean and std.dev: (1441.79, 753.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6403)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (245, 426, 1715)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4655)
[M::mem_pestat] mean and std.dev: (951.65, 985.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6125)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705190 sequences (100000003 bp) in 2.348 CPU sec, 2.742 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 281698, 31, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 347, 658)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1638)
[M::mem_pestat] mean and std.dev: (372.45, 326.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2128)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 226, 327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 677)
[M::mem_pestat] mean and std.dev: (249.77, 124.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 852)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (400, 562, 2064)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5392)
[M::mem_pestat] mean and std.dev: (1079.48, 931.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7056)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 431, 1023)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2675)
[M::mem_pestat] mean and std.dev: (551.92, 456.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3501)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703776 sequences (100000092 bp) in 1.745 CPU sec, 1.773 real sec...
[M::mem_process_seqs] Processed 705984 reads in 184.318 CPU sec, 5.951 real sec
sorting block 33, #reads = 1071593 mem = 536878604 peak = 1083846656
[M::mem_process_seqs] Processed 705496 reads in 127.483 CPU sec, 4.087 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 282067, 22, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 475, 1461)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3959)
[M::mem_pestat] mean and std.dev: (763.74, 820.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5208)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 226, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 680)
[M::mem_pestat] mean and std.dev: (250.38, 124.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 856)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (326, 543, 989)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2315)
[M::mem_pestat] mean and std.dev: (668.10, 523.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2978)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 272, 515)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1215)
[M::mem_pestat] mean and std.dev: (254.35, 124.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1565)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 34, #reads = 1071601 mem = 536879431 peak = 1083846656
[M::process] read 702998 sequences (100000184 bp) in 2.759 CPU sec, 3.412 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 281278, 37, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 393, 617)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1507)
[M::mem_pestat] mean and std.dev: (376.11, 259.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1952)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 230, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 689)
[M::mem_pestat] mean and std.dev: (253.76, 125.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 867)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (322, 482, 1637)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4267)
[M::mem_pestat] mean and std.dev: (961.51, 921.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5582)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 346, 1111)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2953)
[M::mem_pestat] mean and std.dev: (636.91, 766.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3874)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702288 sequences (100000169 bp) in 1.735 CPU sec, 1.751 real sec...
[M::mem_process_seqs] Processed 705190 reads in 184.753 CPU sec, 6.050 real sec
[M::mem_process_seqs] Processed 703776 reads in 129.444 CPU sec, 4.289 real sec
sorting block 35, #reads = 1072805 mem = 536880388 peak = 1083846656
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 281304, 17, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (142, 257, 786)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2074)
[M::mem_pestat] mean and std.dev: (361.10, 350.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2718)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 231, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 693)
[M::mem_pestat] mean and std.dev: (255.36, 126.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 872)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (804, 1217, 2589)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6159)
[M::mem_pestat] mean and std.dev: (1370.29, 909.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7944)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 405, 976)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2578)
[M::mem_pestat] mean and std.dev: (495.76, 476.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3379)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701530 sequences (100000186 bp) in 2.417 CPU sec, 2.682 real sec...
[M::process] read 701434 sequences (100000029 bp) in 1.827 CPU sec, 1.867 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 281119, 21, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 278, 953)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2425)
[M::mem_pestat] mean and std.dev: (439.39, 347.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3161)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 233, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 700)
[M::mem_pestat] mean and std.dev: (257.14, 127.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 881)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (114, 892, 1318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3726)
[M::mem_pestat] mean and std.dev: (780.84, 800.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4930)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 402, 1315)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3565)
[M::mem_pestat] mean and std.dev: (717.87, 935.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4690)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702998 reads in 186.197 CPU sec, 6.072 real sec
[M::mem_process_seqs] Processed 702288 reads in 127.466 CPU sec, 4.122 real sec
sorting block 36, #reads = 1070590 mem = 536877563 peak = 1083846656
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 280468, 42, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 404, 1082)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2932)
[M::mem_pestat] mean and std.dev: (591.98, 616.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3857)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 234, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 701)
[M::mem_pestat] mean and std.dev: (258.21, 127.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 882)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (238, 696, 1538)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4138)
[M::mem_pestat] mean and std.dev: (935.88, 921.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5438)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 325, 2061)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5741)
[M::mem_pestat] mean and std.dev: (824.56, 1133.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7581)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701106 sequences (100000206 bp) in 2.495 CPU sec, 2.770 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 280611, 33, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 444, 1329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3599)
[M::mem_pestat] mean and std.dev: (812.11, 704.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4734)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 235, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 704)
[M::mem_pestat] mean and std.dev: (259.28, 128.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 886)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (552, 831, 2445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6231)
[M::mem_pestat] mean and std.dev: (1266.10, 1112.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8124)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (297, 488, 1286)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3264)
[M::mem_pestat] mean and std.dev: (757.86, 674.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4253)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701222 sequences (100000247 bp) in 1.700 CPU sec, 1.708 real sec...
[M::mem_process_seqs] Processed 701530 reads in 185.497 CPU sec, 6.006 real sec
sorting block 37, #reads = 1071143 mem = 536877984 peak = 1083846656
[M::mem_process_seqs] Processed 701434 reads in 127.597 CPU sec, 4.190 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 280138, 25, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (263, 458, 1296)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3362)
[M::mem_pestat] mean and std.dev: (761.45, 726.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4395)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 236, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 713)
[M::mem_pestat] mean and std.dev: (260.45, 129.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 898)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 483, 2295)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6477)
[M::mem_pestat] mean and std.dev: (1350.44, 1632.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8568)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (246, 382, 891)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2181)
[M::mem_pestat] mean and std.dev: (632.38, 558.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2866)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700562 sequences (100000292 bp) in 2.129 CPU sec, 2.320 real sec...
[M::process] read 700514 sequences (100000026 bp) in 1.708 CPU sec, 1.745 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 280605, 19, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 304, 938)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2506)
[M::mem_pestat] mean and std.dev: (494.88, 469.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3290)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 237, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 710)
[M::mem_pestat] mean and std.dev: (260.39, 129.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 894)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (715, 1966, 2411)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5803)
[M::mem_pestat] mean and std.dev: (1514.42, 907.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7499)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 559, 1778)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4902)
[M::mem_pestat] mean and std.dev: (792.73, 859.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6464)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701106 reads in 186.673 CPU sec, 6.110 real sec
sorting block 38, #reads = 1070235 mem = 536878954 peak = 1083846656
[M::mem_process_seqs] Processed 701222 reads in 126.516 CPU sec, 4.111 real sec
sorting block 39, #reads = 1069759 mem = 536879766 peak = 1145278464
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 280581, 31, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (226, 310, 797)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1939)
[M::mem_pestat] mean and std.dev: (387.10, 255.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2510)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 237, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 711)
[M::mem_pestat] mean and std.dev: (261.15, 129.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 895)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (549, 1106, 2317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5853)
[M::mem_pestat] mean and std.dev: (1397.16, 1206.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7621)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 452, 856)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2256)
[M::mem_pestat] mean and std.dev: (543.52, 491.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2956)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700910 sequences (100000278 bp) in 2.436 CPU sec, 2.857 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 279959, 29, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 334, 1197)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3183)
[M::mem_pestat] mean and std.dev: (609.02, 571.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4176)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 237, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 714)
[M::mem_pestat] mean and std.dev: (261.75, 129.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 899)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (575, 1032, 2406)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6068)
[M::mem_pestat] mean and std.dev: (1482.85, 1401.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7899)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 266, 600)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1356)
[M::mem_pestat] mean and std.dev: (317.54, 218.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1734)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700428 sequences (100000137 bp) in 1.646 CPU sec, 1.654 real sec...
[M::mem_process_seqs] Processed 700562 reads in 186.753 CPU sec, 6.129 real sec
[M::mem_process_seqs] Processed 700514 reads in 128.032 CPU sec, 4.211 real sec
sorting block 40, #reads = 1070555 mem = 536880719 peak = 1145278464
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 280270, 26, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 287, 661)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1543)
[M::mem_pestat] mean and std.dev: (441.47, 350.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1984)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 235, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 698)
[M::mem_pestat] mean and std.dev: (258.24, 127.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 878)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (247, 437, 878)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2140)
[M::mem_pestat] mean and std.dev: (563.54, 502.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2771)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 322, 2289)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6555)
[M::mem_pestat] mean and std.dev: (1324.47, 1837.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8688)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700586 sequences (100000116 bp) in 2.408 CPU sec, 2.958 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 279969, 33, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 307, 903)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2381)
[M::mem_pestat] mean and std.dev: (424.09, 383.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3120)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 237, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 703)
[M::mem_pestat] mean and std.dev: (260.43, 128.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 884)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (475, 819, 1164)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2542)
[M::mem_pestat] mean and std.dev: (721.54, 329.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3231)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 429, 1409)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3885)
[M::mem_pestat] mean and std.dev: (668.61, 708.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5123)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700230 sequences (100000281 bp) in 1.689 CPU sec, 1.706 real sec...
[M::mem_process_seqs] Processed 700910 reads in 187.474 CPU sec, 6.137 real sec
[M::mem_process_seqs] Processed 700428 reads in 127.606 CPU sec, 4.095 real sec
sorting block 41, #reads = 1069736 mem = 536880447 peak = 1145278464
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 279931, 15, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 651, 2114)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5914)
[M::mem_pestat] mean and std.dev: (1058.83, 967.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7814)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 236, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 699)
[M::mem_pestat] mean and std.dev: (259.09, 127.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 879)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1000, 1634, 5285)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13855)
[M::mem_pestat] mean and std.dev: (2719.53, 2655.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 18140)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (231, 357, 627)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1419)
[M::mem_pestat] mean and std.dev: (449.41, 342.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1818)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700046 sequences (100000258 bp) in 2.509 CPU sec, 2.861 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 279928, 26, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (346, 823, 1698)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4402)
[M::mem_pestat] mean and std.dev: (825.44, 776.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5754)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 236, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 702)
[M::mem_pestat] mean and std.dev: (259.57, 127.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 883)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (426, 836, 1223)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2817)
[M::mem_pestat] mean and std.dev: (970.71, 762.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4019)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 489, 1129)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2953)
[M::mem_pestat] mean and std.dev: (573.30, 507.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3865)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700142 sequences (100000081 bp) in 1.706 CPU sec, 1.726 real sec...
[M::mem_process_seqs] Processed 700586 reads in 189.518 CPU sec, 6.203 real sec
sorting block 42, #reads = 1070022 mem = 536879615 peak = 1145278464
[M::mem_process_seqs] Processed 700230 reads in 132.954 CPU sec, 4.254 real sec
sorting block 43, #reads = 1068314 mem = 536877879 peak = 1147269120
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 280187, 23, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (225, 465, 873)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2169)
[M::mem_pestat] mean and std.dev: (539.37, 427.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2817)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 238, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 706)
[M::mem_pestat] mean and std.dev: (261.27, 128.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 888)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (246, 513, 1245)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3243)
[M::mem_pestat] mean and std.dev: (735.73, 649.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4242)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 294, 707)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1749)
[M::mem_pestat] mean and std.dev: (439.96, 438.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2270)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699578 sequences (100000207 bp) in 2.277 CPU sec, 2.510 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 279984, 25, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 279, 930)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2468)
[M::mem_pestat] mean and std.dev: (459.18, 388.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3237)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 237, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 703)
[M::mem_pestat] mean and std.dev: (260.38, 128.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 884)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (635, 1043, 2806)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7148)
[M::mem_pestat] mean and std.dev: (1396.68, 973.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9319)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 420, 1072)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2784)
[M::mem_pestat] mean and std.dev: (555.88, 498.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3640)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699516 sequences (100000166 bp) in 1.720 CPU sec, 1.815 real sec...
[M::mem_process_seqs] Processed 700046 reads in 185.126 CPU sec, 5.976 real sec
[M::mem_process_seqs] Processed 700142 reads in 137.518 CPU sec, 4.441 real sec
sorting block 44, #reads = 1069012 mem = 536878175 peak = 1147269120
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 279254, 49, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 407, 1329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3623)
[M::mem_pestat] mean and std.dev: (730.55, 906.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4770)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 238, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 704)
[M::mem_pestat] mean and std.dev: (261.30, 127.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 885)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 476, 1610)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4406)
[M::mem_pestat] mean and std.dev: (680.33, 712.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5804)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 353, 816)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2026)
[M::mem_pestat] mean and std.dev: (518.42, 461.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2631)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699968 sequences (100000003 bp) in 2.317 CPU sec, 2.768 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 279534, 26, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 371, 695)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1757)
[M::mem_pestat] mean and std.dev: (405.18, 300.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2288)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 239, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 710)
[M::mem_pestat] mean and std.dev: (262.25, 129.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 893)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (744, 1300, 1376)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2640)
[M::mem_pestat] mean and std.dev: (996.55, 567.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3272)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 297, 859)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2177)
[M::mem_pestat] mean and std.dev: (442.46, 484.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2836)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699572 sequences (100000061 bp) in 1.698 CPU sec, 1.728 real sec...
[M::mem_process_seqs] Processed 699578 reads in 185.761 CPU sec, 6.057 real sec
[M::mem_process_seqs] Processed 699516 reads in 131.710 CPU sec, 4.283 real sec
sorting block 45, #reads = 1068115 mem = 536882591 peak = 1147269120
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 280407, 25, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 381, 1410)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3928)
[M::mem_pestat] mean and std.dev: (735.93, 845.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5187)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 238, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 712)
[M::mem_pestat] mean and std.dev: (262.28, 130.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 896)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (515, 1416, 2366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6068)
[M::mem_pestat] mean and std.dev: (1386.40, 854.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7919)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 349, 1211)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3223)
[M::mem_pestat] mean and std.dev: (719.54, 795.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4229)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699698 sequences (100000050 bp) in 2.355 CPU sec, 2.826 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 279720, 28, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 808, 1618)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4416)
[M::mem_pestat] mean and std.dev: (932.14, 866.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5815)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 239, 346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 716)
[M::mem_pestat] mean and std.dev: (263.46, 130.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 901)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (584, 1219, 2076)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5060)
[M::mem_pestat] mean and std.dev: (1227.69, 902.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6552)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 374, 1150)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3076)
[M::mem_pestat] mean and std.dev: (647.66, 728.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4039)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699906 sequences (100000093 bp) in 1.681 CPU sec, 1.842 real sec...
[M::mem_process_seqs] Processed 699968 reads in 188.939 CPU sec, 6.114 real sec
sorting block 46, #reads = 1067134 mem = 536880669 peak = 1147269120
[M::mem_process_seqs] Processed 699572 reads in 130.750 CPU sec, 4.279 real sec
sorting block 47, #reads = 1067618 mem = 536878783 peak = 1147269120
[M::process] read 703424 sequences (100000293 bp) in 2.525 CPU sec, 2.723 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 280145, 26, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 426, 692)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1724)
[M::mem_pestat] mean and std.dev: (492.31, 391.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2240)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 238, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 706)
[M::mem_pestat] mean and std.dev: (261.44, 129.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 888)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (347, 588, 1300)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3206)
[M::mem_pestat] mean and std.dev: (767.26, 680.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4159)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 323, 1048)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2754)
[M::mem_pestat] mean and std.dev: (672.78, 755.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3694)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704588 sequences (100000190 bp) in 1.805 CPU sec, 1.822 real sec...
[M::mem_process_seqs] Processed 699906 reads in 113.970 CPU sec, 3.661 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 279778, 29, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 436, 1525)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4137)
[M::mem_pestat] mean and std.dev: (839.05, 1044.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5443)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 238, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 712)
[M::mem_pestat] mean and std.dev: (262.28, 130.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 896)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 1215, 2273)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6449)
[M::mem_pestat] mean and std.dev: (1325.69, 1287.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8537)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 379, 992)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2534)
[M::mem_pestat] mean and std.dev: (611.16, 541.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3305)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 280739, 21, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 306, 1333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3623)
[M::mem_pestat] mean and std.dev: (694.95, 781.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4768)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 230, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 692)
[M::mem_pestat] mean and std.dev: (254.54, 126.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 871)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (76, 241, 957)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2719)
[M::mem_pestat] mean and std.dev: (458.05, 458.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3600)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 341, 838)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2064)
[M::mem_pestat] mean and std.dev: (474.62, 419.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2677)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704676 sequences (100000212 bp) in 1.821 CPU sec, 1.842 real sec...
[M::mem_process_seqs] Processed 699698 reads in 299.421 CPU sec, 9.728 real sec
sorting block 48, #reads = 1066698 mem = 536878244 peak = 1147269120
[M::mem_process_seqs] Processed 703424 reads in 160.162 CPU sec, 5.192 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 281496, 17, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (328, 866, 1516)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3892)
[M::mem_pestat] mean and std.dev: (821.06, 646.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5080)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 227, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 681)
[M::mem_pestat] mean and std.dev: (251.13, 124.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 857)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (271, 659, 1839)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4975)
[M::mem_pestat] mean and std.dev: (963.29, 825.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6543)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (289, 417, 1484)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3874)
[M::mem_pestat] mean and std.dev: (841.70, 764.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5069)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 49, #reads = 1067039 mem = 536880386 peak = 1163632640
[M::process] read 703768 sequences (100000182 bp) in 2.495 CPU sec, 2.889 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 281947, 28, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 306, 614)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1470)
[M::mem_pestat] mean and std.dev: (327.43, 225.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1898)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 227, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 687)
[M::mem_pestat] mean and std.dev: (251.94, 125.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 865)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (457, 642, 1211)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2719)
[M::mem_pestat] mean and std.dev: (828.42, 697.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3618)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 259, 483)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1147)
[M::mem_pestat] mean and std.dev: (255.86, 130.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1479)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703522 sequences (100000258 bp) in 1.845 CPU sec, 1.895 real sec...
[M::mem_process_seqs] Processed 704588 reads in 181.182 CPU sec, 5.859 real sec
[M::mem_process_seqs] Processed 704676 reads in 127.771 CPU sec, 4.351 real sec
sorting block 50, #reads = 1071907 mem = 536892980 peak = 1163632640
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 281576, 31, 74)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 251, 1222)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3286)
[M::mem_pestat] mean and std.dev: (578.50, 705.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4318)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 229, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 688)
[M::mem_pestat] mean and std.dev: (253.25, 126.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 866)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 546, 751)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1957)
[M::mem_pestat] mean and std.dev: (447.41, 292.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2560)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (405, 733, 1462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3576)
[M::mem_pestat] mean and std.dev: (900.82, 736.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4633)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703188 sequences (100000088 bp) in 2.254 CPU sec, 2.787 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 281318, 14, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (145, 269, 1003)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2719)
[M::mem_pestat] mean and std.dev: (532.00, 492.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3577)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 231, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 695)
[M::mem_pestat] mean and std.dev: (254.92, 126.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 875)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (405, 1032, 1032)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2286)
[M::mem_pestat] mean and std.dev: (793.00, 497.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2913)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 474, 746)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1858)
[M::mem_pestat] mean and std.dev: (468.43, 375.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2414)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702384 sequences (100000146 bp) in 1.734 CPU sec, 1.770 real sec...
[M::mem_process_seqs] Processed 703768 reads in 184.475 CPU sec, 6.220 real sec
[M::mem_process_seqs] Processed 703522 reads in 129.216 CPU sec, 4.177 real sec
sorting block 51, #reads = 1072514 mem = 536878226 peak = 1163632640
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 281487, 11, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (256, 609, 1484)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3940)
[M::mem_pestat] mean and std.dev: (750.06, 648.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5168)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 231, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 695)
[M::mem_pestat] mean and std.dev: (255.03, 126.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 875)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1413, 1427, 4071)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9387)
[M::mem_pestat] mean and std.dev: (2542.82, 2249.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12045)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (279, 931, 1438)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3756)
[M::mem_pestat] mean and std.dev: (1043.39, 751.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4915)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701954 sequences (100000066 bp) in 2.341 CPU sec, 2.656 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 280537, 23, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 294, 972)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2554)
[M::mem_pestat] mean and std.dev: (544.18, 582.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3345)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 233, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 705)
[M::mem_pestat] mean and std.dev: (257.75, 128.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 888)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (345, 804, 1068)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2514)
[M::mem_pestat] mean and std.dev: (646.95, 398.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3237)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 326, 1038)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2740)
[M::mem_pestat] mean and std.dev: (593.77, 709.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3591)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701396 sequences (100000000 bp) in 1.724 CPU sec, 1.731 real sec...
[M::mem_process_seqs] Processed 703188 reads in 182.672 CPU sec, 5.893 real sec
sorting block 52, #reads = 1072437 mem = 536880471 peak = 1163632640
[M::mem_process_seqs] Processed 702384 reads in 135.500 CPU sec, 4.365 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 280536, 28, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (374, 515, 1327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3233)
[M::mem_pestat] mean and std.dev: (623.23, 480.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4186)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 234, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 706)
[M::mem_pestat] mean and std.dev: (258.85, 129.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 889)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (406, 851, 1385)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3343)
[M::mem_pestat] mean and std.dev: (975.48, 817.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4322)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 267, 754)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1822)
[M::mem_pestat] mean and std.dev: (436.25, 418.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2356)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 53, #reads = 1072159 mem = 536882570 peak = 1163632640
[M::process] read 701288 sequences (100000124 bp) in 2.215 CPU sec, 2.962 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 280518, 23, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 537, 1261)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3411)
[M::mem_pestat] mean and std.dev: (687.13, 586.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4486)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 236, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 710)
[M::mem_pestat] mean and std.dev: (260.17, 129.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 894)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (833, 1878, 3192)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7910)
[M::mem_pestat] mean and std.dev: (2282.95, 1904.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10269)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 458, 856)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2124)
[M::mem_pestat] mean and std.dev: (506.00, 334.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2758)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701112 sequences (100000272 bp) in 1.692 CPU sec, 1.721 real sec...
[M::mem_process_seqs] Processed 701954 reads in 180.441 CPU sec, 5.847 real sec
[M::mem_process_seqs] Processed 701396 reads in 126.652 CPU sec, 4.328 real sec
sorting block 54, #reads = 1070820 mem = 536877988 peak = 1163632640
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 280356, 20, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 432, 1049)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2777)
[M::mem_pestat] mean and std.dev: (643.93, 613.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3641)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 236, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 710)
[M::mem_pestat] mean and std.dev: (260.29, 129.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 894)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (77, 369, 1211)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3479)
[M::mem_pestat] mean and std.dev: (631.63, 746.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4613)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 488, 1610)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4422)
[M::mem_pestat] mean and std.dev: (890.39, 937.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5828)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701212 sequences (100000215 bp) in 2.337 CPU sec, 2.876 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 280516, 21, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 356, 471)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1003)
[M::mem_pestat] mean and std.dev: (325.94, 169.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1269)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 237, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 711)
[M::mem_pestat] mean and std.dev: (261.09, 129.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 895)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (652, 918, 3371)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8809)
[M::mem_pestat] mean and std.dev: (1465.60, 1513.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11528)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (239, 358, 929)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2309)
[M::mem_pestat] mean and std.dev: (620.38, 517.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2999)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701576 sequences (100000266 bp) in 1.883 CPU sec, 1.912 real sec...
[M::mem_process_seqs] Processed 701288 reads in 186.479 CPU sec, 6.273 real sec
[M::mem_process_seqs] Processed 701112 reads in 126.979 CPU sec, 4.076 real sec
sorting block 55, #reads = 1069922 mem = 536879746 peak = 1163632640
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 279973, 28, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 352, 901)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2361)
[M::mem_pestat] mean and std.dev: (509.50, 470.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3091)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 236, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 707)
[M::mem_pestat] mean and std.dev: (260.20, 129.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 890)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (102, 295, 1835)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5301)
[M::mem_pestat] mean and std.dev: (951.93, 1186.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7034)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (249, 428, 1081)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2745)
[M::mem_pestat] mean and std.dev: (633.82, 591.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3577)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703256 sequences (100000052 bp) in 2.372 CPU sec, 2.788 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 279878, 24, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (327, 859, 1368)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3450)
[M::mem_pestat] mean and std.dev: (848.77, 611.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4491)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 235, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 709)
[M::mem_pestat] mean and std.dev: (259.51, 129.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 893)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (125, 184, 1408)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3974)
[M::mem_pestat] mean and std.dev: (702.54, 798.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5257)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (256, 431, 1138)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2902)
[M::mem_pestat] mean and std.dev: (605.00, 513.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3784)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701100 sequences (100000121 bp) in 1.718 CPU sec, 1.814 real sec...
[M::mem_process_seqs] Processed 701212 reads in 185.073 CPU sec, 5.999 real sec
sorting block 56, #reads = 1070032 mem = 536879157 peak = 1163632640
[M::mem_process_seqs] Processed 701576 reads in 129.250 CPU sec, 4.402 real sec
sorting block 57, #reads = 1070026 mem = 536882035 peak = 1163632640
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 280499, 28, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 288, 784)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2030)
[M::mem_pestat] mean and std.dev: (451.70, 401.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2653)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 228, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 674)
[M::mem_pestat] mean and std.dev: (251.25, 123.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 847)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (591, 1541, 2422)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6084)
[M::mem_pestat] mean and std.dev: (1463.29, 940.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7915)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (231, 390, 881)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2181)
[M::mem_pestat] mean and std.dev: (538.33, 387.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2831)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700994 sequences (100000051 bp) in 2.496 CPU sec, 2.746 real sec...
[M::process] read 700240 sequences (100000152 bp) in 1.877 CPU sec, 1.915 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 279832, 20, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (230, 411, 1233)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3239)
[M::mem_pestat] mean and std.dev: (690.24, 623.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4242)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 234, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 695)
[M::mem_pestat] mean and std.dev: (257.52, 126.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 874)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 688, 1412)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3800)
[M::mem_pestat] mean and std.dev: (742.72, 708.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4994)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 353, 926)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2456)
[M::mem_pestat] mean and std.dev: (485.83, 444.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3221)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703256 reads in 191.910 CPU sec, 6.419 real sec
[M::mem_process_seqs] Processed 701100 reads in 131.052 CPU sec, 4.239 real sec
sorting block 58, #reads = 1069628 mem = 536877759 peak = 1163632640
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 280012, 34, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 479, 1134)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3020)
[M::mem_pestat] mean and std.dev: (757.15, 657.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3963)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 234, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 695)
[M::mem_pestat] mean and std.dev: (257.60, 126.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 874)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (330, 830, 2082)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5586)
[M::mem_pestat] mean and std.dev: (1344.79, 1273.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7338)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 400, 931)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2415)
[M::mem_pestat] mean and std.dev: (501.18, 460.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3157)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700384 sequences (100000205 bp) in 2.445 CPU sec, 2.802 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 279718, 27, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (261, 465, 903)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2187)
[M::mem_pestat] mean and std.dev: (570.61, 420.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2829)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 236, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 696)
[M::mem_pestat] mean and std.dev: (258.64, 126.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 875)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (500, 821, 2607)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6821)
[M::mem_pestat] mean and std.dev: (1424.07, 1271.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8928)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (280, 942, 1691)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4513)
[M::mem_pestat] mean and std.dev: (964.10, 798.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5924)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700278 sequences (100000174 bp) in 1.706 CPU sec, 1.826 real sec...
[M::mem_process_seqs] Processed 700994 reads in 187.610 CPU sec, 6.086 real sec
[M::mem_process_seqs] Processed 700240 reads in 130.505 CPU sec, 4.288 real sec
sorting block 59, #reads = 1066690 mem = 536877664 peak = 1163632640
[M::process] read 699738 sequences (100000090 bp) in 2.388 CPU sec, 2.746 real sec...
[M::process] read 699582 sequences (100000076 bp) in 1.681 CPU sec, 1.787 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 280059, 35, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (264, 552, 1376)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3600)
[M::mem_pestat] mean and std.dev: (807.03, 713.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4712)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 235, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 693)
[M::mem_pestat] mean and std.dev: (257.54, 125.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 871)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 892, 2478)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7008)
[M::mem_pestat] mean and std.dev: (1341.53, 1314.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9273)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 227, 1352)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3684)
[M::mem_pestat] mean and std.dev: (622.36, 715.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4850)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700278 reads in 104.027 CPU sec, 3.375 real sec
sorting block 60, #reads = 1067605 mem = 536877844 peak = 1163632640
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 279754, 26, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 516, 1099)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2963)
[M::mem_pestat] mean and std.dev: (556.13, 559.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3895)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 236, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 696)
[M::mem_pestat] mean and std.dev: (258.82, 126.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 875)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (728, 1369, 1982)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4490)
[M::mem_pestat] mean and std.dev: (1278.13, 882.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5744)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (249, 438, 761)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1785)
[M::mem_pestat] mean and std.dev: (509.16, 387.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2297)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 280236, 37, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 360, 656)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1602)
[M::mem_pestat] mean and std.dev: (412.51, 322.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2075)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 237, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 688)
[M::mem_pestat] mean and std.dev: (257.81, 124.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 864)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (384, 1032, 3049)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8379)
[M::mem_pestat] mean and std.dev: (1708.62, 1637.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11044)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 301, 622)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1502)
[M::mem_pestat] mean and std.dev: (321.26, 235.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1942)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699398 sequences (100000164 bp) in 1.829 CPU sec, 2.015 real sec...
[M::mem_process_seqs] Processed 700384 reads in 297.093 CPU sec, 9.703 real sec
[M::mem_process_seqs] Processed 699738 reads in 155.207 CPU sec, 5.147 real sec
sorting block 61, #reads = 1067934 mem = 536879745 peak = 1163632640
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 279789, 39, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 460, 1137)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3093)
[M::mem_pestat] mean and std.dev: (604.95, 579.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4071)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 237, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 691)
[M::mem_pestat] mean and std.dev: (258.59, 125.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 868)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (495, 1528, 2339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6027)
[M::mem_pestat] mean and std.dev: (1497.94, 1244.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7871)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (281, 366, 1275)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3263)
[M::mem_pestat] mean and std.dev: (501.27, 460.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4257)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699582 sequences (100000234 bp) in 2.428 CPU sec, 2.713 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 279749, 39, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 255, 1080)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2890)
[M::mem_pestat] mean and std.dev: (475.71, 512.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3795)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 238, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 707)
[M::mem_pestat] mean and std.dev: (261.64, 128.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 889)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (232, 1072, 2779)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7873)
[M::mem_pestat] mean and std.dev: (1817.00, 1934.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10420)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 298, 839)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2141)
[M::mem_pestat] mean and std.dev: (443.34, 351.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2792)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699466 sequences (100000257 bp) in 1.935 CPU sec, 1.988 real sec...
[M::mem_process_seqs] Processed 699582 reads in 190.478 CPU sec, 6.220 real sec
sorting block 62, #reads = 1068164 mem = 536885911 peak = 1163632640
[M::mem_process_seqs] Processed 699398 reads in 130.441 CPU sec, 4.227 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 279810, 26, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (223, 273, 1312)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3490)
[M::mem_pestat] mean and std.dev: (611.36, 606.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4579)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 238, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 709)
[M::mem_pestat] mean and std.dev: (261.66, 129.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 892)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (596, 1238, 2040)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4928)
[M::mem_pestat] mean and std.dev: (1426.28, 1251.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6431)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 391, 959)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2479)
[M::mem_pestat] mean and std.dev: (508.41, 439.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3239)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699288 sequences (100000228 bp) in 2.403 CPU sec, 2.747 real sec...
sorting block 63, #reads = 1067336 mem = 536880850 peak = 1189085184
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 280174, 42, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (244, 487, 1529)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4099)
[M::mem_pestat] mean and std.dev: (848.79, 896.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5384)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 238, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 707)
[M::mem_pestat] mean and std.dev: (261.99, 129.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 889)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (425, 1029, 2396)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6338)
[M::mem_pestat] mean and std.dev: (1825.05, 2045.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10006)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 420, 1468)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4026)
[M::mem_pestat] mean and std.dev: (678.20, 714.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5305)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705664 sequences (100000049 bp) in 1.765 CPU sec, 2.006 real sec...
[M::mem_process_seqs] Processed 699582 reads in 191.111 CPU sec, 6.268 real sec
[M::mem_process_seqs] Processed 699466 reads in 129.042 CPU sec, 4.193 real sec
sorting block 64, #reads = 1067708 mem = 536878891 peak = 1189085184
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 280131, 26, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 374, 817)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2071)
[M::mem_pestat] mean and std.dev: (486.40, 384.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2698)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 240, 347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 719)
[M::mem_pestat] mean and std.dev: (264.60, 131.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 905)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 516, 1915)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5369)
[M::mem_pestat] mean and std.dev: (1013.56, 1038.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7096)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (380, 634, 1627)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4121)
[M::mem_pestat] mean and std.dev: (915.16, 742.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5368)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 708698 sequences (100000108 bp) in 2.331 CPU sec, 2.609 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 281866, 27, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 365, 660)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1596)
[M::mem_pestat] mean and std.dev: (344.29, 244.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2064)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 223, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 664)
[M::mem_pestat] mean and std.dev: (247.21, 123.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 835)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (524, 1393, 3863)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10541)
[M::mem_pestat] mean and std.dev: (1982.67, 1804.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13880)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 770, 1708)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4698)
[M::mem_pestat] mean and std.dev: (840.41, 877.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6193)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706592 sequences (100000082 bp) in 1.902 CPU sec, 1.914 real sec...
[M::mem_process_seqs] Processed 699288 reads in 197.066 CPU sec, 6.380 real sec
[M::mem_process_seqs] Processed 705664 reads in 140.346 CPU sec, 4.540 real sec
sorting block 65, #reads = 1067573 mem = 536878853 peak = 1189085184
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 283624, 34, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 406, 1555)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4295)
[M::mem_pestat] mean and std.dev: (709.40, 738.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5665)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 214, 309)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 633)
[M::mem_pestat] mean and std.dev: (238.02, 117.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 795)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (500, 1006, 1424)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3272)
[M::mem_pestat] mean and std.dev: (932.53, 643.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4196)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 297, 616)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1480)
[M::mem_pestat] mean and std.dev: (329.93, 239.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1912)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704902 sequences (100000271 bp) in 2.419 CPU sec, 2.745 real sec...
[M::process] read 704032 sequences (100000248 bp) in 1.732 CPU sec, 1.738 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 282615, 21, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 530, 1337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3571)
[M::mem_pestat] mean and std.dev: (737.98, 652.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4688)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 219, 318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 654)
[M::mem_pestat] mean and std.dev: (244.23, 121.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 822)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (348, 1078, 2847)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7845)
[M::mem_pestat] mean and std.dev: (1527.81, 1467.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10344)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 401, 925)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2391)
[M::mem_pestat] mean and std.dev: (520.72, 483.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3124)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 708698 reads in 196.926 CPU sec, 6.343 real sec
sorting block 66, #reads = 1067831 mem = 536878956 peak = 1189085184
[M::mem_process_seqs] Processed 706592 reads in 134.310 CPU sec, 4.314 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 282535, 16, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (228, 581, 1468)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3948)
[M::mem_pestat] mean and std.dev: (609.00, 514.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5188)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 224, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 674)
[M::mem_pestat] mean and std.dev: (249.07, 124.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 848)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (710, 726, 1624)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3452)
[M::mem_pestat] mean and std.dev: (952.80, 665.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4366)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (239, 432, 1988)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5486)
[M::mem_pestat] mean and std.dev: (967.57, 1170.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7235)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 67, #reads = 1070896 mem = 536879064 peak = 1189085184
[M::process] read 703402 sequences (100000191 bp) in 2.449 CPU sec, 2.770 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 282381, 22, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 478, 1315)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3567)
[M::mem_pestat] mean and std.dev: (533.38, 485.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4693)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 227, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 685)
[M::mem_pestat] mean and std.dev: (252.81, 127.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 862)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 795, 1520)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4176)
[M::mem_pestat] mean and std.dev: (1057.00, 1064.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5504)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 366, 1312)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3526)
[M::mem_pestat] mean and std.dev: (833.41, 1004.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4852)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702674 sequences (100000196 bp) in 1.856 CPU sec, 1.877 real sec...
[M::mem_process_seqs] Processed 704902 reads in 189.806 CPU sec, 6.158 real sec
[M::process] read 702664 sequences (100000274 bp) in 2.041 CPU sec, 2.070 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 282042, 34, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (247, 742, 2446)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6844)
[M::mem_pestat] mean and std.dev: (1448.14, 1519.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9043)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 228, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 691)
[M::mem_pestat] mean and std.dev: (253.95, 127.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 870)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (270, 1062, 2534)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7062)
[M::mem_pestat] mean and std.dev: (1532.79, 1394.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9326)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (257, 291, 1695)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4571)
[M::mem_pestat] mean and std.dev: (827.20, 909.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6009)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703402 reads in 104.758 CPU sec, 3.482 real sec
sorting block 68, #reads = 1072212 mem = 536883513 peak = 1189085184
[M::mem_process_seqs] Processed 704032 reads in 278.771 CPU sec, 9.116 real sec
sorting block 69, #reads = 1072186 mem = 536882108 peak = 1189085184
[M::process] read 702604 sequences (100000146 bp) in 2.459 CPU sec, 2.823 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 281346, 28, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (278, 571, 757)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1715)
[M::mem_pestat] mean and std.dev: (468.25, 283.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2194)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 230, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 696)
[M::mem_pestat] mean and std.dev: (256.61, 129.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 876)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (295, 597, 1792)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4786)
[M::mem_pestat] mean and std.dev: (1110.75, 1019.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6283)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (292, 488, 1039)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2533)
[M::mem_pestat] mean and std.dev: (659.78, 586.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3280)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702162 sequences (100000137 bp) in 1.752 CPU sec, 1.773 real sec...
[M::mem_process_seqs] Processed 702664 reads in 111.706 CPU sec, 3.608 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 281222, 36, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 325, 625)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1493)
[M::mem_pestat] mean and std.dev: (445.03, 381.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1970)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 229, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 689)
[M::mem_pestat] mean and std.dev: (254.80, 127.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 867)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (394, 814, 1414)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3454)
[M::mem_pestat] mean and std.dev: (904.88, 710.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4474)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (264, 353, 1347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3513)
[M::mem_pestat] mean and std.dev: (536.21, 456.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4596)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 281117, 20, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 758, 1625)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4453)
[M::mem_pestat] mean and std.dev: (910.76, 872.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5867)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 231, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 696)
[M::mem_pestat] mean and std.dev: (256.43, 128.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 876)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 981, 3062)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8738)
[M::mem_pestat] mean and std.dev: (1106.00, 1077.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11576)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 424, 596)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1360)
[M::mem_pestat] mean and std.dev: (414.63, 254.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1742)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701540 sequences (100000246 bp) in 2.121 CPU sec, 2.141 real sec...
[M::mem_process_seqs] Processed 702674 reads in 319.747 CPU sec, 10.377 real sec
sorting block 70, #reads = 1069746 mem = 536879189 peak = 1189085184
[M::mem_process_seqs] Processed 702604 reads in 155.651 CPU sec, 5.034 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 281463, 25, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 602, 1124)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2952)
[M::mem_pestat] mean and std.dev: (621.14, 471.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3866)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 233, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 709)
[M::mem_pestat] mean and std.dev: (259.08, 130.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 893)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 564, 952)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2476)
[M::mem_pestat] mean and std.dev: (451.00, 410.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3238)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 238, 422)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 898)
[M::mem_pestat] mean and std.dev: (254.64, 137.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1136)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701600 sequences (100000131 bp) in 2.332 CPU sec, 2.623 real sec...
sorting block 71, #reads = 1069203 mem = 536878042 peak = 1189085184
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 280093, 34, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (265, 468, 1077)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2701)
[M::mem_pestat] mean and std.dev: (628.93, 634.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3513)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 233, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 703)
[M::mem_pestat] mean and std.dev: (258.51, 129.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 885)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (775, 1281, 2586)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6208)
[M::mem_pestat] mean and std.dev: (1731.35, 1450.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8019)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 415, 1299)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3553)
[M::mem_pestat] mean and std.dev: (641.17, 705.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4680)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701060 sequences (100000118 bp) in 1.950 CPU sec, 2.098 real sec...
[M::mem_process_seqs] Processed 702162 reads in 196.045 CPU sec, 6.514 real sec
[M::mem_process_seqs] Processed 701540 reads in 137.518 CPU sec, 4.444 real sec
sorting block 72, #reads = 1067154 mem = 536880761 peak = 1189085184
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 280318, 27, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (254, 611, 857)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2063)
[M::mem_pestat] mean and std.dev: (579.49, 413.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2666)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 233, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 706)
[M::mem_pestat] mean and std.dev: (258.89, 129.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 889)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (454, 1412, 9792)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 28468)
[M::mem_pestat] mean and std.dev: (3361.89, 3937.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 37806)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 559, 1585)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4325)
[M::mem_pestat] mean and std.dev: (926.44, 979.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5695)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700770 sequences (100000001 bp) in 2.261 CPU sec, 2.545 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 279223, 17, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 513, 2578)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7298)
[M::mem_pestat] mean and std.dev: (1188.20, 1435.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9658)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 234, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 704)
[M::mem_pestat] mean and std.dev: (259.54, 129.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 886)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (362, 501, 785)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1631)
[M::mem_pestat] mean and std.dev: (553.00, 381.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2079)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 312, 1187)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3163)
[M::mem_pestat] mean and std.dev: (689.17, 636.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4151)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700780 sequences (100000048 bp) in 1.738 CPU sec, 1.825 real sec...
[M::mem_process_seqs] Processed 701600 reads in 195.341 CPU sec, 6.315 real sec
[M::mem_process_seqs] Processed 701060 reads in 135.747 CPU sec, 4.360 real sec
sorting block 73, #reads = 1066679 mem = 536878305 peak = 1189085184
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 279896, 19, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 261, 751)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1919)
[M::mem_pestat] mean and std.dev: (331.33, 280.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2503)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 235, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 702)
[M::mem_pestat] mean and std.dev: (259.67, 129.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 883)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (382, 1198, 1808)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4660)
[M::mem_pestat] mean and std.dev: (949.67, 722.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6086)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 307, 2042)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5792)
[M::mem_pestat] mean and std.dev: (898.39, 1271.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7667)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700556 sequences (100000243 bp) in 2.245 CPU sec, 2.555 real sec...
[M::process] read 700212 sequences (100000196 bp) in 1.936 CPU sec, 1.990 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 279999, 37, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (279, 428, 855)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2007)
[M::mem_pestat] mean and std.dev: (449.32, 328.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2583)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 234, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 699)
[M::mem_pestat] mean and std.dev: (258.66, 128.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 879)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (392, 1497, 4946)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 14054)
[M::mem_pestat] mean and std.dev: (2648.46, 3046.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 18608)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 341, 685)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1737)
[M::mem_pestat] mean and std.dev: (326.55, 254.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2263)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700770 reads in 195.348 CPU sec, 6.316 real sec
sorting block 74, #reads = 1064781 mem = 536882132 peak = 1189085184
[M::mem_process_seqs] Processed 700780 reads in 136.487 CPU sec, 4.386 real sec
sorting block 75, #reads = 1065734 mem = 536877266 peak = 1189085184
[M::process] read 700316 sequences (100000125 bp) in 2.387 CPU sec, 2.708 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 280040, 19, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 463, 871)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2257)
[M::mem_pestat] mean and std.dev: (507.92, 461.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2950)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::process] read 700236 sequences (100000032 bp) in 1.787 CPU sec, 2.001 real sec...
[M::mem_pestat] (25, 50, 75) percentile: (159, 236, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 705)
[M::mem_pestat] mean and std.dev: (260.56, 129.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 887)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 314, 1211)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3325)
[M::mem_pestat] mean and std.dev: (552.50, 630.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4382)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (241, 430, 2165)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6013)
[M::mem_pestat] mean and std.dev: (1172.83, 1322.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7937)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700212 reads in 113.041 CPU sec, 3.687 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 280250, 22, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 367, 1150)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3026)
[M::mem_pestat] mean and std.dev: (648.90, 739.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3964)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 235, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 705)
[M::mem_pestat] mean and std.dev: (260.10, 129.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 887)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (665, 905, 1634)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3572)
[M::mem_pestat] mean and std.dev: (1040.45, 614.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4541)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (275, 471, 2986)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8408)
[M::mem_pestat] mean and std.dev: (1458.48, 2083.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11119)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 279764, 31, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 370, 1161)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3043)
[M::mem_pestat] mean and std.dev: (586.00, 572.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3984)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 235, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 699)
[M::mem_pestat] mean and std.dev: (259.59, 128.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 879)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (490, 733, 1773)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4339)
[M::mem_pestat] mean and std.dev: (1200.23, 1066.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5622)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 378, 1200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3172)
[M::mem_pestat] mean and std.dev: (605.84, 586.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4158)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700210 sequences (100000041 bp) in 1.963 CPU sec, 1.986 real sec...
[M::mem_process_seqs] Processed 700556 reads in 309.925 CPU sec, 10.110 real sec
sorting block 76, #reads = 1066494 mem = 536878804 peak = 1189085184
[M::mem_process_seqs] Processed 700316 reads in 162.608 CPU sec, 5.411 real sec
sorting block 77, #reads = 1065003 mem = 536879020 peak = 1189085184
[M::process] read 699948 sequences (100000004 bp) in 2.587 CPU sec, 2.938 real sec...
[M::process] read 700236 sequences (100000184 bp) in 1.893 CPU sec, 1.953 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 279891, 23, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 302, 1035)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2701)
[M::mem_pestat] mean and std.dev: (517.06, 458.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3534)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 236, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 705)
[M::mem_pestat] mean and std.dev: (260.08, 128.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 887)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (300, 877, 3268)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9204)
[M::mem_pestat] mean and std.dev: (1771.04, 1751.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12172)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 438, 1457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3929)
[M::mem_pestat] mean and std.dev: (871.39, 919.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5165)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700210 reads in 109.750 CPU sec, 3.595 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 279823, 29, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 673, 1929)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5379)
[M::mem_pestat] mean and std.dev: (1182.86, 1277.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7104)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 236, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 703)
[M::mem_pestat] mean and std.dev: (260.27, 128.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 884)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (250, 1056, 3759)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10777)
[M::mem_pestat] mean and std.dev: (1827.83, 2256.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14286)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (245, 512, 1337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3521)
[M::mem_pestat] mean and std.dev: (884.19, 955.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4706)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 279847, 21, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (229, 359, 1177)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3073)
[M::mem_pestat] mean and std.dev: (680.71, 645.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4021)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 237, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 703)
[M::mem_pestat] mean and std.dev: (260.61, 128.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 884)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (397, 766, 3730)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10396)
[M::mem_pestat] mean and std.dev: (1494.62, 1567.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13729)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (251, 685, 2671)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7511)
[M::mem_pestat] mean and std.dev: (1388.82, 1550.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9931)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699650 sequences (100000024 bp) in 1.966 CPU sec, 2.007 real sec...
[M::mem_process_seqs] Processed 700236 reads in 310.034 CPU sec, 10.136 real sec
sorting block 78, #reads = 1065131 mem = 536879073 peak = 1189085184
[M::mem_process_seqs] Processed 699948 reads in 161.269 CPU sec, 5.307 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 279731, 21, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (242, 346, 959)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2393)
[M::mem_pestat] mean and std.dev: (542.60, 541.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3110)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 236, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 703)
[M::mem_pestat] mean and std.dev: (260.44, 128.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 884)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (472, 755, 1084)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2308)
[M::mem_pestat] mean and std.dev: (663.56, 362.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2920)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 443, 1056)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2710)
[M::mem_pestat] mean and std.dev: (651.26, 577.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3537)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699704 sequences (100000192 bp) in 2.190 CPU sec, 2.694 real sec...
sorting block 79, #reads = 1064748 mem = 536878692 peak = 1189085184
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 280003, 36, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 465, 1671)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4615)
[M::mem_pestat] mean and std.dev: (868.43, 1061.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6087)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 238, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 712)
[M::mem_pestat] mean and std.dev: (262.45, 130.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 896)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (586, 1582, 2530)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6418)
[M::mem_pestat] mean and std.dev: (1970.06, 1756.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8996)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 310, 1846)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5184)
[M::mem_pestat] mean and std.dev: (701.22, 896.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6853)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 707974 sequences (100000056 bp) in 2.042 CPU sec, 2.142 real sec...
[M::mem_process_seqs] Processed 700236 reads in 199.876 CPU sec, 6.543 real sec
[M::process] read 711232 sequences (100000046 bp) in 1.931 CPU sec, 1.999 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 283021, 26, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (229, 525, 1575)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4267)
[M::mem_pestat] mean and std.dev: (744.50, 670.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5613)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 217, 314)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 646)
[M::mem_pestat] mean and std.dev: (241.31, 120.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 812)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (413, 979, 1780)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4514)
[M::mem_pestat] mean and std.dev: (1053.16, 795.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5881)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 358, 566)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1324)
[M::mem_pestat] mean and std.dev: (432.63, 338.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1787)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 707974 reads in 113.123 CPU sec, 3.832 real sec
sorting block 80, #reads = 1065419 mem = 536877953 peak = 1189085184
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 280078, 20, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 428, 975)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2613)
[M::mem_pestat] mean and std.dev: (606.78, 599.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3432)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 238, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 712)
[M::mem_pestat] mean and std.dev: (262.58, 130.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 896)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (510, 1082, 3299)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8877)
[M::mem_pestat] mean and std.dev: (1637.60, 1512.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11666)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (235, 552, 1939)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5347)
[M::mem_pestat] mean and std.dev: (1077.79, 1084.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7051)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699704 reads in 228.492 CPU sec, 8.079 real sec
[M::process] read 710660 sequences (100000139 bp) in 2.552 CPU sec, 2.699 real sec...
sorting block 81, #reads = 1065992 mem = 536880953 peak = 1189085184
[M::mem_process_seqs] Processed 699650 reads in 426.342 CPU sec, 14.415 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 284380, 24, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (290, 532, 1607)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4241)
[M::mem_pestat] mean and std.dev: (976.36, 928.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5558)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (144, 210, 301)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 615)
[M::mem_pestat] mean and std.dev: (232.66, 114.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 772)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (270, 852, 2203)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6069)
[M::mem_pestat] mean and std.dev: (1240.50, 1144.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8002)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 316, 830)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2136)
[M::mem_pestat] mean and std.dev: (400.82, 362.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2789)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 708500 sequences (100000078 bp) in 2.054 CPU sec, 2.353 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 284777, 19, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 447, 1283)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3461)
[M::mem_pestat] mean and std.dev: (805.03, 822.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4550)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 211, 303)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 619)
[M::mem_pestat] mean and std.dev: (233.81, 114.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 777)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (496, 791, 2003)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5017)
[M::mem_pestat] mean and std.dev: (1090.24, 1294.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6524)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 256, 630)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1490)
[M::mem_pestat] mean and std.dev: (406.48, 332.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1920)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 707048 sequences (100000008 bp) in 1.911 CPU sec, 1.916 real sec...
[M::mem_process_seqs] Processed 711232 reads in 240.744 CPU sec, 7.723 real sec
sorting block 82, #reads = 1067928 mem = 536879680 peak = 1189085184
[M::mem_process_seqs] Processed 710660 reads in 148.423 CPU sec, 4.747 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 283750, 23, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 447, 1783)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4959)
[M::mem_pestat] mean and std.dev: (879.83, 854.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6547)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 215, 310)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 634)
[M::mem_pestat] mean and std.dev: (238.88, 117.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 796)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (289, 666, 1337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3433)
[M::mem_pestat] mean and std.dev: (712.86, 603.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4481)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 344, 524)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1140)
[M::mem_pestat] mean and std.dev: (352.23, 244.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1448)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706416 sequences (100000093 bp) in 2.406 CPU sec, 2.872 real sec...
sorting block 83, #reads = 1068065 mem = 536884554 peak = 1189085184
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 283524, 19, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 341, 1120)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2980)
[M::mem_pestat] mean and std.dev: (417.81, 419.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3910)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 219, 317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 651)
[M::mem_pestat] mean and std.dev: (243.30, 120.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 818)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (593, 1097, 2646)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6752)
[M::mem_pestat] mean and std.dev: (1319.44, 1185.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8805)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 344, 1051)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2717)
[M::mem_pestat] mean and std.dev: (488.60, 490.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3550)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705844 sequences (100000037 bp) in 2.040 CPU sec, 2.337 real sec...
[M::mem_process_seqs] Processed 708500 reads in 211.154 CPU sec, 6.943 real sec
[M::mem_process_seqs] Processed 707048 reads in 140.167 CPU sec, 4.654 real sec
sorting block 84, #reads = 1065663 mem = 536880635 peak = 1189085184
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 283064, 18, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 346, 1174)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3142)
[M::mem_pestat] mean and std.dev: (579.86, 648.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4126)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 220, 318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 654)
[M::mem_pestat] mean and std.dev: (244.39, 121.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 822)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (273, 1475, 2701)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7557)
[M::mem_pestat] mean and std.dev: (1398.17, 1129.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9985)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (230, 385, 1648)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4484)
[M::mem_pestat] mean and std.dev: (917.72, 903.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5902)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705258 sequences (100000061 bp) in 2.229 CPU sec, 2.830 real sec...
[M::process] read 705562 sequences (100000156 bp) in 1.924 CPU sec, 1.928 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 282768, 19, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 264, 1336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3636)
[M::mem_pestat] mean and std.dev: (559.58, 638.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4786)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 221, 323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 667)
[M::mem_pestat] mean and std.dev: (247.13, 123.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 839)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (681, 1333, 2250)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5388)
[M::mem_pestat] mean and std.dev: (1431.79, 1023.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6957)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 323, 740)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1790)
[M::mem_pestat] mean and std.dev: (474.11, 353.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2315)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 706416 reads in 208.640 CPU sec, 6.900 real sec
[M::mem_process_seqs] Processed 705844 reads in 139.963 CPU sec, 4.547 real sec
sorting block 85, #reads = 1066960 mem = 536882392 peak = 1189085184
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 282468, 40, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (130, 205, 385)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 895)
[M::mem_pestat] mean and std.dev: (217.17, 116.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1150)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 224, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 674)
[M::mem_pestat] mean and std.dev: (249.20, 124.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 848)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (310, 881, 1575)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4105)
[M::mem_pestat] mean and std.dev: (929.59, 867.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5370)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 399, 668)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1588)
[M::mem_pestat] mean and std.dev: (377.50, 256.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2048)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704854 sequences (100000085 bp) in 2.481 CPU sec, 2.928 real sec...
[M::process] read 704466 sequences (100000130 bp) in 1.986 CPU sec, 2.081 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 282899, 15, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (281, 479, 2253)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6197)
[M::mem_pestat] mean and std.dev: (877.77, 876.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8169)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 223, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 671)
[M::mem_pestat] mean and std.dev: (248.43, 123.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 844)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (404, 693, 1659)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4169)
[M::mem_pestat] mean and std.dev: (1050.80, 1086.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5424)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 624, 822)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2050)
[M::mem_pestat] mean and std.dev: (539.95, 420.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2664)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 705258 reads in 205.476 CPU sec, 6.672 real sec
sorting block 86, #reads = 1067117 mem = 536879151 peak = 1189085184
[M::mem_process_seqs] Processed 705562 reads in 139.037 CPU sec, 4.557 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 282033, 38, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (279, 588, 2035)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5547)
[M::mem_pestat] mean and std.dev: (1182.45, 1350.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7303)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 225, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 678)
[M::mem_pestat] mean and std.dev: (250.27, 124.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 853)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (503, 598, 2585)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6749)
[M::mem_pestat] mean and std.dev: (1366.06, 1474.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8831)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 299, 776)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1966)
[M::mem_pestat] mean and std.dev: (403.86, 415.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2561)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 87, #reads = 1067853 mem = 536879179 peak = 1189085184
[M::process] read 704044 sequences (100000126 bp) in 2.476 CPU sec, 2.703 real sec...
[M::process] read 703422 sequences (100000217 bp) in 1.926 CPU sec, 1.936 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 281826, 33, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 298, 589)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1453)
[M::mem_pestat] mean and std.dev: (355.53, 279.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1885)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 226, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 681)
[M::mem_pestat] mean and std.dev: (251.72, 126.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 857)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 732, 1780)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4904)
[M::mem_pestat] mean and std.dev: (1088.47, 1248.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6466)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (266, 424, 1023)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2537)
[M::mem_pestat] mean and std.dev: (630.23, 611.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3294)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704854 reads in 206.049 CPU sec, 6.815 real sec
[M::mem_process_seqs] Processed 704466 reads in 141.224 CPU sec, 4.614 real sec
sorting block 88, #reads = 1067840 mem = 536878823 peak = 1189085184
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 281030, 29, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 326, 940)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2412)
[M::mem_pestat] mean and std.dev: (599.84, 620.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3148)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 228, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 688)
[M::mem_pestat] mean and std.dev: (253.27, 126.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 866)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 700, 2466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6972)
[M::mem_pestat] mean and std.dev: (957.76, 1093.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9225)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 360, 742)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1798)
[M::mem_pestat] mean and std.dev: (468.34, 357.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2326)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702358 sequences (100000102 bp) in 2.487 CPU sec, 3.010 real sec...
[M::process] read 701990 sequences (100000124 bp) in 2.000 CPU sec, 2.073 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 281472, 32, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 337, 1120)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3012)
[M::mem_pestat] mean and std.dev: (653.74, 731.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3958)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 229, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 689)
[M::mem_pestat] mean and std.dev: (254.19, 127.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 867)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (269, 745, 1631)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4355)
[M::mem_pestat] mean and std.dev: (1031.34, 965.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5717)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 318, 1863)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5253)
[M::mem_pestat] mean and std.dev: (588.61, 785.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6948)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704044 reads in 208.019 CPU sec, 6.758 real sec
[M::mem_process_seqs] Processed 703422 reads in 141.537 CPU sec, 4.581 real sec
sorting block 89, #reads = 1066952 mem = 536883366 peak = 1189085184
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 280344, 21, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 594, 2037)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5717)
[M::mem_pestat] mean and std.dev: (1182.04, 1303.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7557)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 231, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 693)
[M::mem_pestat] mean and std.dev: (256.11, 127.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 872)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (520, 806, 2229)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5647)
[M::mem_pestat] mean and std.dev: (1203.33, 951.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7356)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 326, 1307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3507)
[M::mem_pestat] mean and std.dev: (592.02, 725.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4607)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701428 sequences (100000186 bp) in 2.491 CPU sec, 2.927 real sec...
[M::process] read 700942 sequences (100000142 bp) in 1.965 CPU sec, 2.083 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 280865, 29, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (259, 495, 1733)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4681)
[M::mem_pestat] mean and std.dev: (933.75, 855.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6155)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 232, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 697)
[M::mem_pestat] mean and std.dev: (257.08, 127.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 877)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (421, 575, 1675)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4183)
[M::mem_pestat] mean and std.dev: (896.68, 756.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5437)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 265, 1019)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2627)
[M::mem_pestat] mean and std.dev: (654.96, 686.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3431)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702358 reads in 209.035 CPU sec, 6.858 real sec
sorting block 90, #reads = 1065552 mem = 536882227 peak = 1189085184
[M::mem_process_seqs] Processed 701990 reads in 143.503 CPU sec, 4.625 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 280201, 29, 71)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (238, 413, 465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 919)
[M::mem_pestat] mean and std.dev: (332.69, 172.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1146)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 234, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 701)
[M::mem_pestat] mean and std.dev: (258.69, 128.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 882)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 553, 2063)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5749)
[M::mem_pestat] mean and std.dev: (1314.03, 1493.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7592)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (236, 410, 1084)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2780)
[M::mem_pestat] mean and std.dev: (565.10, 507.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3628)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701284 sequences (100000107 bp) in 2.459 CPU sec, 3.095 real sec...
sorting block 91, #reads = 1065309 mem = 536878491 peak = 1189085184
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 280245, 30, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 345, 814)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2002)
[M::mem_pestat] mean and std.dev: (473.33, 440.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2596)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 234, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 701)
[M::mem_pestat] mean and std.dev: (259.01, 128.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 882)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (400, 1497, 2560)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6880)
[M::mem_pestat] mean and std.dev: (1602.89, 1752.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9040)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 337, 2160)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6172)
[M::mem_pestat] mean and std.dev: (1165.64, 1667.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8178)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701228 sequences (100000114 bp) in 1.940 CPU sec, 1.962 real sec...
[M::mem_process_seqs] Processed 701428 reads in 202.337 CPU sec, 6.596 real sec
[M::mem_process_seqs] Processed 700942 reads in 138.813 CPU sec, 4.560 real sec
sorting block 92, #reads = 1065961 mem = 536882635 peak = 1189085184
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 280053, 43, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 307, 693)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1693)
[M::mem_pestat] mean and std.dev: (329.53, 232.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2193)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 234, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 698)
[M::mem_pestat] mean and std.dev: (258.42, 128.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 878)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (532, 897, 1724)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4108)
[M::mem_pestat] mean and std.dev: (1082.62, 866.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5300)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 260, 432)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 964)
[M::mem_pestat] mean and std.dev: (312.96, 201.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1230)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699750 sequences (100000205 bp) in 2.493 CPU sec, 2.715 real sec...
[M::process] read 699124 sequences (100000121 bp) in 1.950 CPU sec, 2.042 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 280344, 25, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (242, 567, 1297)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3407)
[M::mem_pestat] mean and std.dev: (669.06, 598.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4462)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 234, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 701)
[M::mem_pestat] mean and std.dev: (258.67, 128.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 882)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (229, 1114, 2144)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5974)
[M::mem_pestat] mean and std.dev: (838.14, 865.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7889)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (305, 507, 1236)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3098)
[M::mem_pestat] mean and std.dev: (700.32, 620.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4029)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701284 reads in 205.406 CPU sec, 6.775 real sec
[M::mem_process_seqs] Processed 701228 reads in 142.225 CPU sec, 4.625 real sec
sorting block 93, #reads = 1066468 mem = 536881170 peak = 1189085184
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 280302, 27, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (249, 375, 1489)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3969)
[M::mem_pestat] mean and std.dev: (764.87, 821.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5209)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 237, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 709)
[M::mem_pestat] mean and std.dev: (261.58, 129.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 892)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (291, 507, 1144)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2850)
[M::mem_pestat] mean and std.dev: (660.25, 627.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3703)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 245, 396)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 834)
[M::mem_pestat] mean and std.dev: (257.66, 127.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1053)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699692 sequences (100000054 bp) in 2.414 CPU sec, 2.990 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 279028, 32, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 316, 603)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1485)
[M::mem_pestat] mean and std.dev: (345.27, 254.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1926)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 239, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 710)
[M::mem_pestat] mean and std.dev: (262.85, 129.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 893)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 575, 2042)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5694)
[M::mem_pestat] mean and std.dev: (958.47, 958.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7520)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 355, 932)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2402)
[M::mem_pestat] mean and std.dev: (493.88, 342.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3137)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700992 sequences (100000020 bp) in 1.963 CPU sec, 1.993 real sec...
[M::mem_process_seqs] Processed 699750 reads in 194.395 CPU sec, 6.323 real sec
sorting block 94, #reads = 1064843 mem = 536878617 peak = 1189085184
[M::mem_process_seqs] Processed 699124 reads in 138.270 CPU sec, 4.463 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 280122, 22, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 338, 700)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1726)
[M::mem_pestat] mean and std.dev: (408.00, 383.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2239)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 237, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 709)
[M::mem_pestat] mean and std.dev: (261.89, 130.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 892)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (243, 614, 878)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2148)
[M::mem_pestat] mean and std.dev: (427.22, 283.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2783)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 331, 609)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1525)
[M::mem_pestat] mean and std.dev: (408.23, 303.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1983)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705974 sequences (100000094 bp) in 2.469 CPU sec, 2.824 real sec...
[M::process] read 708472 sequences (100000197 bp) in 1.895 CPU sec, 1.915 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 279692, 32, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 312, 1055)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2787)
[M::mem_pestat] mean and std.dev: (654.24, 677.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3653)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 234, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 698)
[M::mem_pestat] mean and std.dev: (258.72, 128.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 878)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (132, 532, 1550)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4386)
[M::mem_pestat] mean and std.dev: (945.62, 989.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5804)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 434, 1321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3551)
[M::mem_pestat] mean and std.dev: (827.18, 866.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4666)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699692 reads in 198.587 CPU sec, 6.428 real sec
sorting block 95, #reads = 1066383 mem = 536880758 peak = 1189085184
[M::mem_process_seqs] Processed 700992 reads in 141.263 CPU sec, 4.621 real sec
sorting block 96, #reads = 1066757 mem = 536882803 peak = 1210576896
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 281412, 20, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (295, 496, 1388)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3574)
[M::mem_pestat] mean and std.dev: (693.18, 698.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4667)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 221, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 661)
[M::mem_pestat] mean and std.dev: (245.85, 122.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 831)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 884, 2293)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6543)
[M::mem_pestat] mean and std.dev: (899.00, 1129.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8668)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 351, 764)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1978)
[M::mem_pestat] mean and std.dev: (426.23, 399.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2585)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 707352 sequences (100000204 bp) in 2.338 CPU sec, 2.841 real sec...
[M::process] read 706836 sequences (100000044 bp) in 1.869 CPU sec, 1.870 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 283891, 17, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (136, 192, 345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 763)
[M::mem_pestat] mean and std.dev: (223.06, 147.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 972)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 216, 312)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 640)
[M::mem_pestat] mean and std.dev: (239.83, 118.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 804)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (253, 652, 1983)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5443)
[M::mem_pestat] mean and std.dev: (1257.29, 1399.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7173)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 621, 1057)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2767)
[M::mem_pestat] mean and std.dev: (608.27, 474.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3622)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 705974 reads in 212.141 CPU sec, 6.963 real sec
[M::mem_process_seqs] Processed 708472 reads in 134.511 CPU sec, 4.410 real sec
sorting block 97, #reads = 1061967 mem = 536886625 peak = 1210576896
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 283321, 19, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (268, 431, 1254)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3226)
[M::mem_pestat] mean and std.dev: (730.58, 825.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4212)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 219, 317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 653)
[M::mem_pestat] mean and std.dev: (243.04, 120.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 821)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (835, 1430, 2987)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7291)
[M::mem_pestat] mean and std.dev: (1300.73, 841.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9443)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 398, 1300)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3546)
[M::mem_pestat] mean and std.dev: (672.05, 663.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4669)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705114 sequences (100000125 bp) in 2.380 CPU sec, 2.754 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 283537, 19, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (285, 439, 1000)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2430)
[M::mem_pestat] mean and std.dev: (536.58, 433.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3145)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 221, 320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 660)
[M::mem_pestat] mean and std.dev: (245.33, 122.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 830)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (318, 612, 1422)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3630)
[M::mem_pestat] mean and std.dev: (778.44, 584.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4734)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 400, 1322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3534)
[M::mem_pestat] mean and std.dev: (754.31, 772.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4640)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704738 sequences (100000182 bp) in 1.931 CPU sec, 1.944 real sec...
[M::mem_process_seqs] Processed 707352 reads in 190.520 CPU sec, 6.237 real sec
[M::mem_process_seqs] Processed 706836 reads in 126.310 CPU sec, 4.131 real sec
sorting block 98, #reads = 1073558 mem = 536882550 peak = 1210576896
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 282720, 22, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 263, 483)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1117)
[M::mem_pestat] mean and std.dev: (323.97, 213.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1434)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 224, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 668)
[M::mem_pestat] mean and std.dev: (248.04, 122.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 840)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (103, 861, 1832)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5290)
[M::mem_pestat] mean and std.dev: (900.10, 926.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7019)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (277, 475, 1340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3466)
[M::mem_pestat] mean and std.dev: (715.48, 713.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4529)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704228 sequences (100000071 bp) in 2.256 CPU sec, 2.790 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 282959, 16, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 317, 860)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2194)
[M::mem_pestat] mean and std.dev: (443.97, 414.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2861)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 226, 327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 675)
[M::mem_pestat] mean and std.dev: (249.89, 123.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 849)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (516, 1734, 3694)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10050)
[M::mem_pestat] mean and std.dev: (1981.88, 2203.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13228)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (243, 601, 1147)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2955)
[M::mem_pestat] mean and std.dev: (797.52, 677.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3859)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703548 sequences (100000042 bp) in 1.904 CPU sec, 1.950 real sec...
[M::mem_process_seqs] Processed 705114 reads in 187.891 CPU sec, 6.205 real sec
sorting block 99, #reads = 1073907 mem = 536881867 peak = 1210576896
[M::mem_process_seqs] Processed 704738 reads in 125.556 CPU sec, 4.114 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 282550, 20, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 577, 1526)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4170)
[M::mem_pestat] mean and std.dev: (942.90, 1073.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5492)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 228, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 682)
[M::mem_pestat] mean and std.dev: (252.33, 125.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 858)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (627, 2075, 2552)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6402)
[M::mem_pestat] mean and std.dev: (1668.45, 960.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8327)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 436, 984)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2580)
[M::mem_pestat] mean and std.dev: (489.56, 405.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3378)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 100, #reads = 1073348 mem = 536880088 peak = 1219198976
[M::process] read 703110 sequences (100000183 bp) in 2.359 CPU sec, 2.813 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 282225, 26, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (275, 541, 899)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2147)
[M::mem_pestat] mean and std.dev: (630.87, 488.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2771)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 228, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 685)
[M::mem_pestat] mean and std.dev: (253.03, 125.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 862)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (330, 708, 1011)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2373)
[M::mem_pestat] mean and std.dev: (600.81, 432.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3054)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (240, 432, 732)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1716)
[M::mem_pestat] mean and std.dev: (449.11, 312.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2208)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704020 sequences (100000275 bp) in 1.873 CPU sec, 1.995 real sec...
[M::mem_process_seqs] Processed 704228 reads in 194.363 CPU sec, 6.396 real sec
[M::mem_process_seqs] Processed 703548 reads in 134.406 CPU sec, 4.388 real sec
sorting block 101, #reads = 1073001 mem = 536879413 peak = 1219198976
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 281999, 35, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (276, 380, 984)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2400)
[M::mem_pestat] mean and std.dev: (563.09, 392.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3108)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 229, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 692)
[M::mem_pestat] mean and std.dev: (254.37, 126.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 871)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (460, 935, 1533)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3679)
[M::mem_pestat] mean and std.dev: (901.66, 672.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4752)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 251, 1031)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2739)
[M::mem_pestat] mean and std.dev: (509.76, 558.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3593)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703292 sequences (100000035 bp) in 2.246 CPU sec, 2.772 real sec...
[M::process] read 702824 sequences (100000181 bp) in 1.902 CPU sec, 1.965 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 282475, 21, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 545, 969)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2559)
[M::mem_pestat] mean and std.dev: (616.86, 513.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3354)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 228, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 685)
[M::mem_pestat] mean and std.dev: (252.30, 125.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 862)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (398, 1187, 1650)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4154)
[M::mem_pestat] mean and std.dev: (1018.00, 923.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5406)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 410, 1238)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3278)
[M::mem_pestat] mean and std.dev: (646.10, 665.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4298)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703110 reads in 196.984 CPU sec, 6.411 real sec
[M::mem_process_seqs] Processed 704020 reads in 130.512 CPU sec, 4.223 real sec
sorting block 102, #reads = 1069994 mem = 536880314 peak = 1219198976
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 282095, 17, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 337, 777)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1963)
[M::mem_pestat] mean and std.dev: (417.59, 339.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2556)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 229, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 689)
[M::mem_pestat] mean and std.dev: (253.99, 126.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 867)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (454, 497, 1698)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4186)
[M::mem_pestat] mean and std.dev: (993.82, 1045.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5430)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 487, 702)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1688)
[M::mem_pestat] mean and std.dev: (508.65, 454.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2328)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702814 sequences (100000227 bp) in 2.501 CPU sec, 2.788 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 281891, 26, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 486, 1057)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2803)
[M::mem_pestat] mean and std.dev: (622.86, 622.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3676)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 231, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 693)
[M::mem_pestat] mean and std.dev: (255.55, 126.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 872)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 899, 2261)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6353)
[M::mem_pestat] mean and std.dev: (1528.04, 1530.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8399)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (250, 493, 1398)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3694)
[M::mem_pestat] mean and std.dev: (853.57, 806.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4842)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703558 sequences (100000245 bp) in 1.932 CPU sec, 1.934 real sec...
[M::mem_process_seqs] Processed 703292 reads in 191.310 CPU sec, 6.201 real sec
sorting block 103, #reads = 1071741 mem = 536885222 peak = 1219198976
[M::mem_process_seqs] Processed 702824 reads in 130.519 CPU sec, 4.187 real sec
sorting block 104, #reads = 1069841 mem = 536878753 peak = 1228234752
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 281253, 26, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 430, 1311)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3497)
[M::mem_pestat] mean and std.dev: (787.98, 787.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4590)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 230, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 689)
[M::mem_pestat] mean and std.dev: (254.09, 125.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 867)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (702, 1727, 2926)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7374)
[M::mem_pestat] mean and std.dev: (1751.27, 1105.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9598)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 326, 875)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2223)
[M::mem_pestat] mean and std.dev: (384.32, 302.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2897)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702694 sequences (100000068 bp) in 2.434 CPU sec, 2.686 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 281771, 16, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 384, 819)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2071)
[M::mem_pestat] mean and std.dev: (486.31, 442.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2697)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 227, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 676)
[M::mem_pestat] mean and std.dev: (250.91, 123.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 850)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (273, 440, 1031)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2547)
[M::mem_pestat] mean and std.dev: (502.71, 422.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3305)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 629, 1001)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2551)
[M::mem_pestat] mean and std.dev: (619.66, 459.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3326)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702050 sequences (100000011 bp) in 1.949 CPU sec, 2.066 real sec...
[M::mem_process_seqs] Processed 702814 reads in 194.238 CPU sec, 6.300 real sec
[M::process] read 702128 sequences (100000167 bp) in 2.074 CPU sec, 2.092 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 281181, 27, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (386, 822, 1582)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3974)
[M::mem_pestat] mean and std.dev: (932.50, 695.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5170)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 231, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 690)
[M::mem_pestat] mean and std.dev: (255.24, 126.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 868)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (559, 1216, 1776)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4210)
[M::mem_pestat] mean and std.dev: (1240.16, 747.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5427)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 354, 1099)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3005)
[M::mem_pestat] mean and std.dev: (602.70, 641.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3958)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702694 reads in 111.409 CPU sec, 3.617 real sec
sorting block 105, #reads = 1070084 mem = 536879401 peak = 1228234752
[M::mem_process_seqs] Processed 703558 reads in 289.566 CPU sec, 9.383 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 281047, 28, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (288, 668, 1720)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4584)
[M::mem_pestat] mean and std.dev: (1031.06, 1063.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6016)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 232, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 696)
[M::mem_pestat] mean and std.dev: (256.63, 127.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 876)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (123, 539, 1003)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2763)
[M::mem_pestat] mean and std.dev: (584.65, 615.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3643)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 377, 674)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1680)
[M::mem_pestat] mean and std.dev: (376.47, 275.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2183)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 106, #reads = 1069227 mem = 536881903 peak = 1229017088
[M::process] read 701672 sequences (100000148 bp) in 2.419 CPU sec, 2.836 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 280896, 20, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 328, 985)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2599)
[M::mem_pestat] mean and std.dev: (492.97, 451.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3406)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 231, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 694)
[M::mem_pestat] mean and std.dev: (256.51, 127.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 873)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (398, 1398, 2825)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7679)
[M::mem_pestat] mean and std.dev: (1952.50, 2118.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10428)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 418, 2525)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7145)
[M::mem_pestat] mean and std.dev: (1480.09, 1824.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9455)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701924 sequences (100000044 bp) in 1.883 CPU sec, 1.934 real sec...
[M::mem_process_seqs] Processed 702050 reads in 229.290 CPU sec, 7.483 real sec
[M::mem_process_seqs] Processed 702128 reads in 141.235 CPU sec, 4.674 real sec
sorting block 107, #reads = 1067529 mem = 536879337 peak = 1229017088
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 280303, 21, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 310, 755)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1901)
[M::mem_pestat] mean and std.dev: (505.81, 435.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2474)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 232, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 692)
[M::mem_pestat] mean and std.dev: (257.06, 127.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 870)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (551, 752, 4462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12284)
[M::mem_pestat] mean and std.dev: (2175.81, 2522.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 16195)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 388, 578)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1388)
[M::mem_pestat] mean and std.dev: (382.75, 317.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1793)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701350 sequences (100000259 bp) in 2.215 CPU sec, 2.509 real sec...
[M::process] read 701120 sequences (100000244 bp) in 1.898 CPU sec, 1.921 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 280559, 30, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 262, 460)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1066)
[M::mem_pestat] mean and std.dev: (276.97, 177.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1369)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 231, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 685)
[M::mem_pestat] mean and std.dev: (255.44, 126.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 861)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (439, 1032, 1843)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4651)
[M::mem_pestat] mean and std.dev: (1185.25, 1072.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6055)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 382, 1017)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2645)
[M::mem_pestat] mean and std.dev: (469.86, 419.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3459)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701672 reads in 206.965 CPU sec, 6.739 real sec
sorting block 108, #reads = 1065499 mem = 536885925 peak = 1229017088
[M::process] read 700808 sequences (100000135 bp) in 2.116 CPU sec, 2.187 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 279959, 23, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 753, 1799)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4935)
[M::mem_pestat] mean and std.dev: (934.29, 851.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6503)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 233, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 692)
[M::mem_pestat] mean and std.dev: (257.24, 126.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 870)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (392, 1411, 2494)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6698)
[M::mem_pestat] mean and std.dev: (1417.39, 1114.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8800)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (272, 456, 1370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3566)
[M::mem_pestat] mean and std.dev: (767.78, 702.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4664)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701350 reads in 113.398 CPU sec, 3.756 real sec
[M::mem_process_seqs] Processed 701924 reads in 293.852 CPU sec, 9.561 real sec
sorting block 109, #reads = 1065190 mem = 536882504 peak = 1229017088
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 279772, 22, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (253, 359, 2351)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6547)
[M::mem_pestat] mean and std.dev: (899.83, 1226.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8645)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 233, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 692)
[M::mem_pestat] mean and std.dev: (257.33, 127.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 870)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (103, 681, 1008)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2818)
[M::mem_pestat] mean and std.dev: (621.10, 590.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3723)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 314, 1086)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2848)
[M::mem_pestat] mean and std.dev: (577.77, 620.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3729)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700810 sequences (100000132 bp) in 2.308 CPU sec, 2.532 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 280219, 33, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (258, 513, 1234)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3186)
[M::mem_pestat] mean and std.dev: (658.90, 584.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4162)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 234, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 698)
[M::mem_pestat] mean and std.dev: (258.71, 128.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 878)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (301, 1133, 1366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3496)
[M::mem_pestat] mean and std.dev: (1006.87, 769.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4561)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 303, 907)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2395)
[M::mem_pestat] mean and std.dev: (393.54, 369.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3139)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700842 sequences (100000027 bp) in 1.920 CPU sec, 1.942 real sec...
[M::mem_process_seqs] Processed 701120 reads in 233.667 CPU sec, 7.552 real sec
sorting block 110, #reads = 1065151 mem = 536879357 peak = 1229017088
[M::mem_process_seqs] Processed 700808 reads in 144.652 CPU sec, 4.740 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 280198, 26, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (126, 249, 921)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2511)
[M::mem_pestat] mean and std.dev: (516.46, 627.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3306)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 235, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 699)
[M::mem_pestat] mean and std.dev: (259.07, 128.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 879)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (67, 198, 2084)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6118)
[M::mem_pestat] mean and std.dev: (865.92, 1018.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8135)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 377, 2143)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6073)
[M::mem_pestat] mean and std.dev: (1181.50, 1330.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8038)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706446 sequences (100000196 bp) in 2.396 CPU sec, 2.695 real sec...
[M::process] read 712902 sequences (100000189 bp) in 2.000 CPU sec, 2.007 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 279968, 37, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 433, 1668)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4628)
[M::mem_pestat] mean and std.dev: (764.21, 901.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6108)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 233, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 695)
[M::mem_pestat] mean and std.dev: (257.65, 127.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 874)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (426, 880, 1520)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3708)
[M::mem_pestat] mean and std.dev: (942.52, 757.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4802)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (303, 390, 643)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1323)
[M::mem_pestat] mean and std.dev: (408.83, 234.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1663)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700810 reads in 214.945 CPU sec, 7.027 real sec
sorting block 111, #reads = 1064573 mem = 536879682 peak = 1229017088
[M::mem_process_seqs] Processed 700842 reads in 151.713 CPU sec, 4.947 real sec
sorting block 112, #reads = 1060608 mem = 536879266 peak = 1229017088
[M::process] read 711444 sequences (100000153 bp) in 2.432 CPU sec, 2.707 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 281472, 32, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (236, 668, 1384)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3680)
[M::mem_pestat] mean and std.dev: (803.22, 809.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4828)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 220, 318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 654)
[M::mem_pestat] mean and std.dev: (244.16, 121.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 822)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (466, 915, 2450)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6418)
[M::mem_pestat] mean and std.dev: (1356.93, 1533.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8402)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 416, 729)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1813)
[M::mem_pestat] mean and std.dev: (546.04, 470.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2427)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 709974 sequences (100000058 bp) in 1.954 CPU sec, 1.960 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 284802, 18, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 581, 1191)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3173)
[M::mem_pestat] mean and std.dev: (713.39, 621.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4164)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (143, 206, 295)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 599)
[M::mem_pestat] mean and std.dev: (228.20, 111.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 751)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 568, 1507)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4093)
[M::mem_pestat] mean and std.dev: (780.53, 780.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5386)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 299, 756)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1864)
[M::mem_pestat] mean and std.dev: (468.24, 398.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2418)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 283979, 23, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 327, 1427)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3911)
[M::mem_pestat] mean and std.dev: (742.72, 862.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5153)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (144, 209, 302)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 618)
[M::mem_pestat] mean and std.dev: (233.28, 114.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 776)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (506, 1080, 1814)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4430)
[M::mem_pestat] mean and std.dev: (1128.36, 940.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5738)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 265, 765)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1903)
[M::mem_pestat] mean and std.dev: (430.36, 343.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2472)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 706446 reads in 322.848 CPU sec, 10.468 real sec
[M::mem_process_seqs] Processed 712902 reads in 242.199 CPU sec, 7.787 real sec
[M::mem_process_seqs] Processed 711444 reads in 269.642 CPU sec, 8.712 real sec
sorting block 113, #reads = 1055633 mem = 536879509 peak = 1229017088
[M::process] read 708714 sequences (100000095 bp) in 2.385 CPU sec, 2.810 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 283936, 32, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 213, 600)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1432)
[M::mem_pestat] mean and std.dev: (259.53, 190.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1848)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 213, 308)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 632)
[M::mem_pestat] mean and std.dev: (236.94, 116.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 794)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (119, 359, 1513)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4301)
[M::mem_pestat] mean and std.dev: (757.74, 975.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5695)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (297, 552, 859)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1983)
[M::mem_pestat] mean and std.dev: (499.56, 327.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2545)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 114, #reads = 1068044 mem = 536881759 peak = 1229017088
[M::process] read 707542 sequences (100000134 bp) in 2.235 CPU sec, 2.443 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 283842, 24, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (144, 234, 890)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2382)
[M::mem_pestat] mean and std.dev: (377.57, 352.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3128)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 216, 314)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 646)
[M::mem_pestat] mean and std.dev: (240.66, 118.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 812)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (295, 793, 1164)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2902)
[M::mem_pestat] mean and std.dev: (820.25, 649.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3771)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 251, 480)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1096)
[M::mem_pestat] mean and std.dev: (281.95, 208.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1404)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 709974 reads in 214.767 CPU sec, 7.012 real sec
[M::process] read 706620 sequences (100000092 bp) in 1.849 CPU sec, 1.876 real sec...
[M::mem_process_seqs] Processed 708714 reads in 148.734 CPU sec, 4.797 real sec
sorting block 115, #reads = 1068253 mem = 536883091 peak = 1229017088
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 283287, 21, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 459, 1409)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3803)
[M::mem_pestat] mean and std.dev: (658.27, 675.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5000)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::process] read 705634 sequences (100000068 bp) in 2.189 CPU sec, 2.566 real sec...
[M::mem_pestat] (25, 50, 75) percentile: (149, 219, 317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 653)
[M::mem_pestat] mean and std.dev: (243.08, 120.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 821)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (113, 759, 2277)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6605)
[M::mem_pestat] mean and std.dev: (1122.67, 1263.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8769)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 304, 622)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1518)
[M::mem_pestat] mean and std.dev: (378.54, 372.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1966)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705556 sequences (100000134 bp) in 1.842 CPU sec, 1.864 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 283337, 19, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 858, 1894)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5320)
[M::mem_pestat] mean and std.dev: (1102.08, 985.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7033)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 221, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 663)
[M::mem_pestat] mean and std.dev: (245.83, 121.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 834)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (334, 503, 1324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3304)
[M::mem_pestat] mean and std.dev: (709.44, 451.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4294)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (237, 324, 595)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1311)
[M::mem_pestat] mean and std.dev: (337.98, 241.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1669)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 707542 reads in 208.382 CPU sec, 6.712 real sec
sorting block 116, #reads = 1066183 mem = 536880663 peak = 1229017088
[M::mem_process_seqs] Processed 706620 reads in 142.958 CPU sec, 4.590 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 282202, 24, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (242, 423, 836)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2024)
[M::mem_pestat] mean and std.dev: (516.61, 393.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2618)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 223, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 673)
[M::mem_pestat] mean and std.dev: (248.08, 123.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 847)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (492, 830, 2535)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6621)
[M::mem_pestat] mean and std.dev: (1376.09, 1197.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8664)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (279, 1060, 2655)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7407)
[M::mem_pestat] mean and std.dev: (1796.22, 1959.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9783)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706062 sequences (100000060 bp) in 2.366 CPU sec, 2.992 real sec...
[M::process] read 705322 sequences (100000116 bp) in 1.919 CPU sec, 1.924 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 281835, 38, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 196, 671)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1687)
[M::mem_pestat] mean and std.dev: (361.39, 358.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2195)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 223, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 671)
[M::mem_pestat] mean and std.dev: (248.64, 123.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 844)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (321, 641, 1165)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2853)
[M::mem_pestat] mean and std.dev: (900.45, 750.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3902)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 383, 621)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1509)
[M::mem_pestat] mean and std.dev: (363.87, 231.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1953)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 705634 reads in 207.848 CPU sec, 6.701 real sec
sorting block 117, #reads = 1067649 mem = 536878820 peak = 1229017088
[M::mem_process_seqs] Processed 705556 reads in 144.495 CPU sec, 4.620 real sec
sorting block 118, #reads = 1066687 mem = 536878674 peak = 1229017088
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 281694, 22, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (277, 396, 1008)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2470)
[M::mem_pestat] mean and std.dev: (514.62, 448.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3201)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 222, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 670)
[M::mem_pestat] mean and std.dev: (247.68, 124.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 843)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (273, 914, 1886)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5112)
[M::mem_pestat] mean and std.dev: (1185.48, 951.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6725)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 362, 1069)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2829)
[M::mem_pestat] mean and std.dev: (570.57, 510.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3709)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706090 sequences (100000191 bp) in 2.554 CPU sec, 2.817 real sec...
[M::process] read 704366 sequences (100000295 bp) in 1.778 CPU sec, 1.822 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 281686, 22, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 354, 1432)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3888)
[M::mem_pestat] mean and std.dev: (787.18, 836.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5116)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 225, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 680)
[M::mem_pestat] mean and std.dev: (250.40, 125.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 856)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (337, 658, 2326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6304)
[M::mem_pestat] mean and std.dev: (950.86, 863.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8293)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (268, 582, 1340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3484)
[M::mem_pestat] mean and std.dev: (804.72, 738.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4556)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 706062 reads in 209.181 CPU sec, 6.719 real sec
[M::mem_process_seqs] Processed 705322 reads in 141.427 CPU sec, 4.550 real sec
sorting block 119, #reads = 1064598 mem = 536878298 peak = 1229017088
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 282468, 18, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 402, 760)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1904)
[M::mem_pestat] mean and std.dev: (464.74, 366.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2476)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 221, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 661)
[M::mem_pestat] mean and std.dev: (246.03, 122.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 831)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (502, 1126, 3184)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8548)
[M::mem_pestat] mean and std.dev: (1857.12, 1973.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11230)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 310, 898)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2326)
[M::mem_pestat] mean and std.dev: (461.51, 419.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3040)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702868 sequences (100000204 bp) in 2.413 CPU sec, 2.823 real sec...
[M::process] read 702032 sequences (100000291 bp) in 1.909 CPU sec, 1.912 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 280837, 33, 73)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 371, 1055)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2767)
[M::mem_pestat] mean and std.dev: (556.27, 564.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3623)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 225, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 666)
[M::mem_pestat] mean and std.dev: (248.65, 122.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 837)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (443, 514, 2310)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6044)
[M::mem_pestat] mean and std.dev: (1112.47, 1364.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7911)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (233, 507, 1263)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3323)
[M::mem_pestat] mean and std.dev: (719.52, 690.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4353)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 706090 reads in 206.495 CPU sec, 6.650 real sec
sorting block 120, #reads = 1067065 mem = 536881359 peak = 1229017088
[M::mem_process_seqs] Processed 704366 reads in 145.373 CPU sec, 4.659 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 281035, 32, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 389, 1227)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3339)
[M::mem_pestat] mean and std.dev: (648.76, 751.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4395)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 230, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 683)
[M::mem_pestat] mean and std.dev: (253.36, 124.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 859)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (302, 846, 1229)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3083)
[M::mem_pestat] mean and std.dev: (792.21, 612.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4010)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (249, 502, 908)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2226)
[M::mem_pestat] mean and std.dev: (565.91, 456.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2885)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701470 sequences (100000034 bp) in 2.481 CPU sec, 2.755 real sec...
[M::process] read 700918 sequences (100000253 bp) in 1.843 CPU sec, 1.901 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 280594, 24, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 454, 1250)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3396)
[M::mem_pestat] mean and std.dev: (907.08, 990.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4870)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 231, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 693)
[M::mem_pestat] mean and std.dev: (255.59, 126.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 872)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (419, 819, 2479)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6599)
[M::mem_pestat] mean and std.dev: (1073.95, 1138.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8659)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 342, 458)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 920)
[M::mem_pestat] mean and std.dev: (306.95, 147.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1151)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702868 reads in 204.720 CPU sec, 6.585 real sec
sorting block 121, #reads = 1065326 mem = 536878311 peak = 1229017088
[M::mem_process_seqs] Processed 702032 reads in 144.330 CPU sec, 4.643 real sec
sorting block 122, #reads = 1065216 mem = 536880130 peak = 1229017088
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 280285, 25, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 349, 582)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1386)
[M::mem_pestat] mean and std.dev: (337.88, 230.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1788)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 233, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 691)
[M::mem_pestat] mean and std.dev: (256.45, 126.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 869)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (754, 1644, 2176)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5020)
[M::mem_pestat] mean and std.dev: (1418.76, 870.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6442)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 372, 882)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2246)
[M::mem_pestat] mean and std.dev: (483.26, 406.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2928)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700938 sequences (100000042 bp) in 2.429 CPU sec, 2.689 real sec...
[M::process] read 700546 sequences (100000234 bp) in 1.974 CPU sec, 2.034 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 280270, 30, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (257, 414, 968)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2390)
[M::mem_pestat] mean and std.dev: (619.40, 534.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3101)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 234, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 687)
[M::mem_pestat] mean and std.dev: (257.00, 125.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 863)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 785, 2606)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7384)
[M::mem_pestat] mean and std.dev: (1253.66, 1436.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9773)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (238, 481, 749)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1771)
[M::mem_pestat] mean and std.dev: (496.19, 335.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2282)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701470 reads in 201.418 CPU sec, 6.497 real sec
[M::mem_process_seqs] Processed 700918 reads in 139.032 CPU sec, 4.464 real sec
sorting block 123, #reads = 1065678 mem = 536881295 peak = 1229017088
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 280522, 21, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (251, 397, 775)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1823)
[M::mem_pestat] mean and std.dev: (441.02, 340.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2347)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 233, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 680)
[M::mem_pestat] mean and std.dev: (254.73, 123.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 854)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (294, 353, 1175)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2937)
[M::mem_pestat] mean and std.dev: (812.25, 737.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3818)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 239, 710)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1794)
[M::mem_pestat] mean and std.dev: (418.24, 402.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2336)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700042 sequences (100000213 bp) in 2.299 CPU sec, 2.591 real sec...
[M::process] read 699868 sequences (100000189 bp) in 1.760 CPU sec, 1.830 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 280391, 19, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 451, 903)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2299)
[M::mem_pestat] mean and std.dev: (575.96, 528.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2997)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 235, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 690)
[M::mem_pestat] mean and std.dev: (257.32, 125.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 867)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (432, 575, 1715)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4281)
[M::mem_pestat] mean and std.dev: (1061.58, 917.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5564)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (231, 454, 766)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1836)
[M::mem_pestat] mean and std.dev: (415.58, 308.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2371)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700938 reads in 198.152 CPU sec, 6.377 real sec
[M::mem_process_seqs] Processed 700546 reads in 135.690 CPU sec, 4.347 real sec
sorting block 124, #reads = 1064517 mem = 536880632 peak = 1229017088
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 279845, 14, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (235, 334, 1042)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2656)
[M::mem_pestat] mean and std.dev: (390.62, 321.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3463)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 236, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 691)
[M::mem_pestat] mean and std.dev: (257.91, 125.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 868)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (359, 931, 1143)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2711)
[M::mem_pestat] mean and std.dev: (771.00, 599.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3495)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (246, 472, 1123)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2877)
[M::mem_pestat] mean and std.dev: (533.61, 425.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3754)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699338 sequences (100000041 bp) in 2.447 CPU sec, 2.907 real sec...
[M::process] read 699384 sequences (100000083 bp) in 1.623 CPU sec, 1.630 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 279791, 33, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 329, 599)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1465)
[M::mem_pestat] mean and std.dev: (399.02, 323.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1898)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 237, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 703)
[M::mem_pestat] mean and std.dev: (260.74, 128.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 884)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (227, 782, 1326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3524)
[M::mem_pestat] mean and std.dev: (921.52, 773.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4623)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (233, 355, 1066)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2732)
[M::mem_pestat] mean and std.dev: (620.45, 615.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3565)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700042 reads in 193.873 CPU sec, 6.244 real sec
sorting block 125, #reads = 1065703 mem = 536880145 peak = 1229017088
[M::mem_process_seqs] Processed 699868 reads in 133.169 CPU sec, 4.271 real sec
sorting block 126, #reads = 1066281 mem = 536880264 peak = 1229017088
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 279430, 26, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 195, 495)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1173)
[M::mem_pestat] mean and std.dev: (292.66, 241.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1512)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 238, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 706)
[M::mem_pestat] mean and std.dev: (261.22, 128.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 888)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (810, 1191, 1873)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3999)
[M::mem_pestat] mean and std.dev: (1271.12, 753.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5062)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (232, 446, 1200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3136)
[M::mem_pestat] mean and std.dev: (622.05, 548.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4104)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 547558 sequences (78190926 bp) in 2.125 CPU sec, 2.371 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 279800, 25, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (279, 521, 1406)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3660)
[M::mem_pestat] mean and std.dev: (898.15, 873.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4787)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 239, 345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 713)
[M::mem_pestat] mean and std.dev: (262.93, 130.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 897)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (433, 949, 1290)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3004)
[M::mem_pestat] mean and std.dev: (760.57, 407.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3861)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 341, 901)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2309)
[M::mem_pestat] mean and std.dev: (444.96, 319.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3013)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699338 reads in 189.034 CPU sec, 6.152 real sec
[M::mem_process_seqs] Processed 699384 reads in 130.691 CPU sec, 4.241 real sec
sorting block 127, #reads = 1067304 mem = 536877909 peak = 1229017088
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 218659, 19, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (269, 362, 768)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1766)
[M::mem_pestat] mean and std.dev: (433.17, 361.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2265)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 237, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 709)
[M::mem_pestat] mean and std.dev: (261.19, 129.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 892)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (451, 869, 3300)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8998)
[M::mem_pestat] mean and std.dev: (1559.00, 1752.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11847)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 375, 919)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2377)
[M::mem_pestat] mean and std.dev: (488.21, 514.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3106)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 547558 reads in 91.383 CPU sec, 3.078 real sec
sorting block 128, #reads = 1065005 mem = 536882809 peak = 1229017088
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000a06d1
  features: 1f8bfbff fffab20b
  extended: f1bf27eb 1b407f7e
  amd bits: 2c100800 00000121
     brand: Intel(R) Xeon(R) 6975P-C
threads: 31
algo: bwa-mem
license: sentieon:klib=31
reads: 136779168
overall: 70769553408 mem 22636.124 user 156.495 sys 753.193 real
[main] Version: 0.7.17-r1188
[main] CMD: /opt/conda/share/sentieon-202308.03-3/libexec/bwa mem -K 100000000 -Y -R @RG\tID:A23MHWWLT4.1136_76X-T1-TDNA-1_A23MHWWLT4_1.L004\tPU:L004\tSM:1136_76X-T1-TDNA-1_A23MHWWLT4_1\tLB:1136_76X-T1-TDNA-1_A23MHWWLT4_1\tDS:s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta\tPL:ILLUMINA -t 31 ./BWAIndex/Homo_sapiens_assembly38.fasta.64 1136_76X-T1-TDNA-1_A23MHWWLT4_1_R1.fastq.gz 1136_76X-T1-TDNA-1_A23MHWWLT4_1_R2.fastq.gz
[main] Real time: 753.228 sec; CPU: 22792.621 sec
sorting block 129, #reads = 107550 mem = 54920091 peak = 1229017088
uniq header count 1
merging 130 blocks
sw version: sentieon-genomics-202308.03
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000a06d1
  features: 1f8bfbff fffab20b
  extended: f1bf27eb 1b407f7e
  amd bits: 2c100800 00000121
     brand: Intel(R) Xeon(R) 6975P-C
threads: 31 max 64
algo: util-sort
license: sentieon:util=1
output file size: 7922261102
output reads: 137914991
bam_mem_sort: 130 calls 75.413 user 0.085 sys 79.228 real
bam_write: 130 calls 78.568 user 3.697 sys 187.227 real
execute: 1 calls 38.475 user 0.779 sys 802.362 real
merge_files: 1 calls 38.448 user 0.760 sys 49.048 real
parse_chunk: 2066 calls 89.740 user 21.885 sys 150.690 real
read_chunk: 5595 calls 47.791 user 23.950 sys 710.625 real
sort_block: 1 calls 30.414 user 23.418 sys 688.836 real
write_chunk: 3527 calls 38.073 user 0.508 sys 48.072 real
overall: 3698585600 mem 1928.079 user 59.661 sys 802.380 real
ls: cannot access '*.cram': No such file or directory