cmdline: /opt/conda/share/sentieon-202308.03-3/libexec/util sort -r Homo_sapiens_assembly38.fasta -t 31 -o 1136_76X-T1-TDNA-1_A23MHWWLT4_1.bam --sam2bam -
This software is licensed to bgold@natera.com by Sentieon Inc.
This software is licensed to bgold@natera.com by Sentieon Inc.
version: sentieon-genomics-202308.03
[M::bwa_idx_load_from_disk] read 3171 ALT contigs
[M::main_mem] bwa index loaded in 2160.070 CPU sec, 83.191 real sec
[M::process] read 706138 sequences (100000123 bp) in 1.718 CPU sec, 1.724 real sec...
[M::process] read 703388 sequences (100000270 bp) in 1.880 CPU sec, 1.972 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 281972, 10, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 435, 1123)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3023)
[M::mem_pestat] mean and std.dev: (545.61, 582.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3973)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 221, 319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 655)
[M::mem_pestat] mean and std.dev: (244.81, 120.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 823)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (535, 965, 2174)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5452)
[M::mem_pestat] mean and std.dev: (1552.20, 1373.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7091)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 345, 1084)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2818)
[M::mem_pestat] mean and std.dev: (623.40, 705.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3685)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703046 sequences (100000203 bp) in 1.908 CPU sec, 1.969 real sec...
[M::process] read 702284 sequences (100000002 bp) in 1.875 CPU sec, 1.943 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 281293, 21, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 288, 472)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1112)
[M::mem_pestat] mean and std.dev: (290.26, 215.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1432)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 229, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 683)
[M::mem_pestat] mean and std.dev: (252.76, 125.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 859)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (552, 698, 1989)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4863)
[M::mem_pestat] mean and std.dev: (1316.90, 1213.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6300)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (237, 506, 922)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2292)
[M::mem_pestat] mean and std.dev: (595.12, 523.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2977)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 706138 reads in 233.396 CPU sec, 7.545 real sec
[M::process] read 702100 sequences (100000069 bp) in 2.423 CPU sec, 2.438 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 280690, 31, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 395, 1251)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3389)
[M::mem_pestat] mean and std.dev: (703.89, 697.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4458)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 230, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 689)
[M::mem_pestat] mean and std.dev: (253.86, 125.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 867)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (409, 2054, 5268)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 14986)
[M::mem_pestat] mean and std.dev: (2921.23, 2606.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 19845)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 360, 785)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1959)
[M::mem_pestat] mean and std.dev: (473.76, 317.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2546)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703046 reads in 133.543 CPU sec, 4.252 real sec
sorting block 0, #reads = 1071639 mem = 536878463 peak = 600276992
[M::mem_process_seqs] Processed 703388 reads in 323.036 CPU sec, 10.418 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 280660, 25, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 302, 545)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1227)
[M::mem_pestat] mean and std.dev: (386.82, 263.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1568)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 232, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 696)
[M::mem_pestat] mean and std.dev: (255.92, 126.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 876)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (413, 467, 986)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2132)
[M::mem_pestat] mean and std.dev: (602.13, 404.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2705)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 294, 547)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1305)
[M::mem_pestat] mean and std.dev: (358.16, 245.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1684)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701182 sequences (100000119 bp) in 3.218 CPU sec, 3.333 real sec...
[M::process] read 701000 sequences (100000187 bp) in 2.030 CPU sec, 2.031 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 280733, 24, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (234, 423, 1516)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4080)
[M::mem_pestat] mean and std.dev: (814.29, 831.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5362)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 233, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 697)
[M::mem_pestat] mean and std.dev: (256.79, 127.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 877)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (599, 1396, 2993)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7781)
[M::mem_pestat] mean and std.dev: (1638.62, 1314.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10175)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 370, 1262)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3392)
[M::mem_pestat] mean and std.dev: (597.63, 627.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4457)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702284 reads in 262.816 CPU sec, 8.384 real sec
sorting block 1, #reads = 1070702 mem = 536877709 peak = 758755328
[M::mem_process_seqs] Processed 702100 reads in 163.705 CPU sec, 5.225 real sec
sorting block 2, #reads = 1070410 mem = 536880177 peak = 854323200
[M::process] read 700318 sequences (100000090 bp) in 2.367 CPU sec, 2.486 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 280446, 45, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 370, 869)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2257)
[M::mem_pestat] mean and std.dev: (546.08, 576.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2951)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 235, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 704)
[M::mem_pestat] mean and std.dev: (259.03, 128.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 886)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (420, 833, 1705)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4275)
[M::mem_pestat] mean and std.dev: (1037.09, 822.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5560)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (252, 429, 1610)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4326)
[M::mem_pestat] mean and std.dev: (814.07, 900.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5684)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700260 sequences (100000141 bp) in 1.805 CPU sec, 1.825 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 280356, 22, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 342, 591)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1355)
[M::mem_pestat] mean and std.dev: (320.83, 159.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1737)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 236, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 708)
[M::mem_pestat] mean and std.dev: (260.31, 129.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 891)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (278, 896, 1989)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5411)
[M::mem_pestat] mean and std.dev: (982.45, 923.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7122)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 301, 962)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2464)
[M::mem_pestat] mean and std.dev: (539.70, 547.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3215)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 280402, 32, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 527, 1066)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2856)
[M::mem_pestat] mean and std.dev: (739.12, 774.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3838)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 237, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 708)
[M::mem_pestat] mean and std.dev: (260.89, 129.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 891)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (374, 639, 1614)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4094)
[M::mem_pestat] mean and std.dev: (691.85, 735.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5334)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 572, 1424)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3868)
[M::mem_pestat] mean and std.dev: (826.57, 846.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5090)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701182 reads in 325.923 CPU sec, 10.534 real sec
[M::mem_process_seqs] Processed 701000 reads in 255.902 CPU sec, 8.337 real sec
[M::mem_process_seqs] Processed 700318 reads in 289.545 CPU sec, 9.462 real sec
sorting block 3, #reads = 1070712 mem = 536880331 peak = 854323200
[M::process] read 699944 sequences (100000199 bp) in 3.377 CPU sec, 3.680 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 280506, 27, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 720, 1623)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4435)
[M::mem_pestat] mean and std.dev: (976.52, 948.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5841)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 239, 345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 715)
[M::mem_pestat] mean and std.dev: (262.89, 130.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 900)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 350, 1456)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3974)
[M::mem_pestat] mean and std.dev: (718.54, 849.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5233)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (290, 333, 1700)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4520)
[M::mem_pestat] mean and std.dev: (915.30, 1006.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5930)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700260 reads in 131.760 CPU sec, 4.326 real sec
sorting block 4, #reads = 1069279 mem = 536886140 peak = 854323200
[M::process] read 699590 sequences (100000081 bp) in 3.130 CPU sec, 3.311 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 280486, 30, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (254, 528, 1651)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4445)
[M::mem_pestat] mean and std.dev: (1065.04, 1166.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5842)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 239, 346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 718)
[M::mem_pestat] mean and std.dev: (263.25, 131.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 904)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (140, 883, 1103)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3029)
[M::mem_pestat] mean and std.dev: (759.34, 624.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3992)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (233, 428, 848)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2078)
[M::mem_pestat] mean and std.dev: (494.18, 370.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2693)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699492 sequences (100000004 bp) in 2.721 CPU sec, 2.831 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 280422, 38, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 494, 1772)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4958)
[M::mem_pestat] mean and std.dev: (964.77, 1160.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6551)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 239, 348)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 722)
[M::mem_pestat] mean and std.dev: (264.65, 132.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 909)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (662, 1058, 3170)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8186)
[M::mem_pestat] mean and std.dev: (1765.33, 1730.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10694)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 512, 1235)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3291)
[M::mem_pestat] mean and std.dev: (646.44, 531.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4319)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699352 sequences (100000089 bp) in 2.070 CPU sec, 2.069 real sec...
[M::mem_process_seqs] Processed 699944 reads in 267.439 CPU sec, 8.547 real sec
sorting block 5, #reads = 1069700 mem = 536882602 peak = 854323200
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 279700, 31, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 351, 908)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2378)
[M::mem_pestat] mean and std.dev: (523.12, 513.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3113)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 240, 346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 716)
[M::mem_pestat] mean and std.dev: (263.68, 130.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 901)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (888, 1319, 2150)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4674)
[M::mem_pestat] mean and std.dev: (1298.00, 828.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5936)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 306, 404)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 848)
[M::mem_pestat] mean and std.dev: (305.38, 129.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1070)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698988 sequences (100000048 bp) in 2.275 CPU sec, 2.276 real sec...
[M::mem_process_seqs] Processed 699492 reads in 134.876 CPU sec, 4.372 real sec
sorting block 6, #reads = 1069941 mem = 536878262 peak = 854323200
[M::mem_process_seqs] Processed 699590 reads in 354.291 CPU sec, 11.402 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 279480, 24, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 327, 599)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1487)
[M::mem_pestat] mean and std.dev: (351.28, 243.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1931)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 239, 346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 716)
[M::mem_pestat] mean and std.dev: (263.76, 130.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 901)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (532, 1020, 1255)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2701)
[M::mem_pestat] mean and std.dev: (881.61, 582.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3424)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (254, 522, 966)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2390)
[M::mem_pestat] mean and std.dev: (560.59, 404.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3102)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698352 sequences (100000200 bp) in 3.452 CPU sec, 3.841 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 279650, 26, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (246, 568, 2241)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6231)
[M::mem_pestat] mean and std.dev: (1125.04, 1260.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8226)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 240, 345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 713)
[M::mem_pestat] mean and std.dev: (263.40, 129.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 897)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (233, 1582, 2016)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5582)
[M::mem_pestat] mean and std.dev: (1312.27, 1161.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7365)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 589, 1148)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2996)
[M::mem_pestat] mean and std.dev: (585.59, 464.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3920)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699352 reads in 270.498 CPU sec, 8.618 real sec
sorting block 7, #reads = 1069298 mem = 536877431 peak = 854323200
[M::process] read 698484 sequences (100000097 bp) in 2.653 CPU sec, 2.729 real sec...
[M::mem_process_seqs] Processed 698988 reads in 169.894 CPU sec, 5.395 real sec
sorting block 8, #reads = 1068435 mem = 536877543 peak = 854323200
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 279251, 30, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (234, 362, 1128)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2916)
[M::mem_pestat] mean and std.dev: (730.84, 698.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3810)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 241, 346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 712)
[M::mem_pestat] mean and std.dev: (264.34, 129.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 895)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (344, 984, 1700)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4412)
[M::mem_pestat] mean and std.dev: (1095.71, 956.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5768)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 352, 1156)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3106)
[M::mem_pestat] mean and std.dev: (562.65, 470.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4081)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698742 sequences (100000253 bp) in 2.630 CPU sec, 2.911 real sec...
[M::process] read 698828 sequences (100000216 bp) in 2.142 CPU sec, 2.147 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 279232, 31, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 255, 610)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1512)
[M::mem_pestat] mean and std.dev: (355.91, 311.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1963)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 240, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 705)
[M::mem_pestat] mean and std.dev: (262.55, 127.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 886)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (258, 742, 2516)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7032)
[M::mem_pestat] mean and std.dev: (1520.29, 1678.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9290)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 282, 609)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1449)
[M::mem_pestat] mean and std.dev: (343.98, 246.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1869)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698352 reads in 242.739 CPU sec, 7.941 real sec
[M::mem_process_seqs] Processed 698484 reads in 169.022 CPU sec, 5.522 real sec
sorting block 9, #reads = 1066920 mem = 536881847 peak = 854323200
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 279407, 31, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (245, 540, 935)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2315)
[M::mem_pestat] mean and std.dev: (613.95, 468.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3005)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 240, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 702)
[M::mem_pestat] mean and std.dev: (261.80, 127.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 882)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 373, 1182)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3132)
[M::mem_pestat] mean and std.dev: (590.69, 748.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4107)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 304, 1125)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2921)
[M::mem_pestat] mean and std.dev: (634.38, 666.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3819)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699112 sequences (100000121 bp) in 3.757 CPU sec, 4.135 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 278835, 29, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 315, 1149)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3043)
[M::mem_pestat] mean and std.dev: (563.20, 630.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3990)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 239, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 699)
[M::mem_pestat] mean and std.dev: (261.35, 127.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 878)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (333, 524, 2440)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6654)
[M::mem_pestat] mean and std.dev: (853.64, 834.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8761)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 439, 1076)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2852)
[M::mem_pestat] mean and std.dev: (832.70, 881.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4360)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698872 sequences (100000299 bp) in 2.420 CPU sec, 2.429 real sec...
[M::mem_process_seqs] Processed 698742 reads in 240.472 CPU sec, 7.760 real sec
[M::mem_process_seqs] Processed 698828 reads in 168.875 CPU sec, 5.494 real sec
sorting block 10, #reads = 1065773 mem = 536885890 peak = 854323200
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 279185, 35, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 368, 560)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1290)
[M::mem_pestat] mean and std.dev: (364.38, 221.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1655)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 239, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 701)
[M::mem_pestat] mean and std.dev: (260.98, 126.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 881)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (237, 632, 2740)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7746)
[M::mem_pestat] mean and std.dev: (1421.00, 1585.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10249)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 245, 494)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1156)
[M::mem_pestat] mean and std.dev: (287.64, 182.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1487)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698852 sequences (100000036 bp) in 3.557 CPU sec, 3.941 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 279212, 36, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 717, 1574)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4348)
[M::mem_pestat] mean and std.dev: (930.04, 899.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5735)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 239, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 699)
[M::mem_pestat] mean and std.dev: (260.85, 126.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 878)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (320, 592, 945)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2195)
[M::mem_pestat] mean and std.dev: (630.91, 413.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2820)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 233, 489)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1117)
[M::mem_pestat] mean and std.dev: (249.83, 123.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1431)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698774 sequences (100000168 bp) in 2.167 CPU sec, 2.173 real sec...
[M::mem_process_seqs] Processed 699112 reads in 242.732 CPU sec, 7.843 real sec
sorting block 11, #reads = 1066250 mem = 536879997 peak = 854323200
[M::mem_process_seqs] Processed 698872 reads in 168.606 CPU sec, 5.378 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 278830, 30, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 341, 717)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1719)
[M::mem_pestat] mean and std.dev: (425.47, 303.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2220)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 239, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 699)
[M::mem_pestat] mean and std.dev: (261.21, 126.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 878)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (411, 1784, 2779)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7515)
[M::mem_pestat] mean and std.dev: (1536.76, 1130.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9883)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (231, 430, 1349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3585)
[M::mem_pestat] mean and std.dev: (864.12, 874.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4703)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 12, #reads = 1065474 mem = 536877918 peak = 854323200
[M::process] read 698826 sequences (100000008 bp) in 3.958 CPU sec, 4.257 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 278959, 37, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (245, 640, 1713)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4649)
[M::mem_pestat] mean and std.dev: (859.18, 846.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6117)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 241, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 708)
[M::mem_pestat] mean and std.dev: (262.58, 127.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 890)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (901, 1014, 1700)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3298)
[M::mem_pestat] mean and std.dev: (984.32, 552.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4097)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (278, 360, 795)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1829)
[M::mem_pestat] mean and std.dev: (469.66, 341.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2346)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698212 sequences (100000113 bp) in 2.518 CPU sec, 2.536 real sec...
[M::mem_process_seqs] Processed 698852 reads in 250.562 CPU sec, 8.086 real sec
[M::mem_process_seqs] Processed 698774 reads in 176.857 CPU sec, 5.635 real sec
sorting block 13, #reads = 1066175 mem = 536879053 peak = 854323200
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 279638, 25, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 425, 986)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2530)
[M::mem_pestat] mean and std.dev: (540.70, 532.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3302)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 241, 345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 711)
[M::mem_pestat] mean and std.dev: (263.63, 128.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 894)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (431, 847, 1310)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3068)
[M::mem_pestat] mean and std.dev: (877.22, 736.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3947)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (236, 535, 1166)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3026)
[M::mem_pestat] mean and std.dev: (660.33, 586.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3956)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702770 sequences (100000146 bp) in 4.001 CPU sec, 4.250 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 279054, 38, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 441, 1930)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5376)
[M::mem_pestat] mean and std.dev: (880.53, 930.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7099)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 243, 348)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 718)
[M::mem_pestat] mean and std.dev: (265.15, 129.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 903)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (391, 1223, 2199)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5815)
[M::mem_pestat] mean and std.dev: (1165.23, 878.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7623)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (261, 510, 1175)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3003)
[M::mem_pestat] mean and std.dev: (739.56, 660.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3917)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698826 reads in 241.283 CPU sec, 7.675 real sec
[M::process] read 703882 sequences (100000086 bp) in 2.690 CPU sec, 2.689 real sec...
[M::mem_process_seqs] Processed 698212 reads in 170.852 CPU sec, 5.747 real sec
sorting block 14, #reads = 1064869 mem = 536879244 peak = 854323200
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 280400, 20, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 308, 808)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2020)
[M::mem_pestat] mean and std.dev: (432.61, 397.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2626)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 231, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 690)
[M::mem_pestat] mean and std.dev: (254.49, 125.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 868)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (325, 776, 2635)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7255)
[M::mem_pestat] mean and std.dev: (1212.26, 1396.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9565)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 293, 934)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2400)
[M::mem_pestat] mean and std.dev: (592.60, 592.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3133)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702942 sequences (100000196 bp) in 3.080 CPU sec, 3.245 real sec...
[M::process] read 702652 sequences (100000003 bp) in 2.346 CPU sec, 2.351 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 281045, 21, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 241, 655)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1665)
[M::mem_pestat] mean and std.dev: (343.24, 299.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2170)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 228, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 685)
[M::mem_pestat] mean and std.dev: (252.41, 125.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 862)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (352, 541, 1089)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2563)
[M::mem_pestat] mean and std.dev: (672.63, 388.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3300)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 401, 983)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2575)
[M::mem_pestat] mean and std.dev: (680.67, 771.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3766)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702770 reads in 244.434 CPU sec, 8.124 real sec
sorting block 15, #reads = 1064921 mem = 536881794 peak = 854323200
[M::mem_process_seqs] Processed 703882 reads in 166.001 CPU sec, 5.339 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 281371, 25, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 347, 729)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1797)
[M::mem_pestat] mean and std.dev: (418.38, 252.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2331)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 231, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 690)
[M::mem_pestat] mean and std.dev: (254.69, 126.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 868)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 223, 1029)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2653)
[M::mem_pestat] mean and std.dev: (460.91, 477.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3465)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 378, 1028)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2660)
[M::mem_pestat] mean and std.dev: (618.38, 599.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3476)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 16, #reads = 1070619 mem = 536877747 peak = 871739392
[M::process] read 702028 sequences (100000125 bp) in 4.102 CPU sec, 4.491 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 281275, 34, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (228, 503, 1964)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5436)
[M::mem_pestat] mean and std.dev: (875.95, 853.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7172)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 232, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 699)
[M::mem_pestat] mean and std.dev: (256.48, 127.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 880)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (612, 1460, 2466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6174)
[M::mem_pestat] mean and std.dev: (1393.17, 980.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8028)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (267, 424, 1546)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4104)
[M::mem_pestat] mean and std.dev: (804.04, 746.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5383)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702942 reads in 228.895 CPU sec, 7.307 real sec
[M::mem_process_seqs] Processed 702652 reads in 162.733 CPU sec, 5.169 real sec
[M::process] read 701554 sequences (100000152 bp) in 3.020 CPU sec, 3.132 real sec...
sorting block 17, #reads = 1071846 mem = 536879683 peak = 871739392
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 280472, 36, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 421, 698)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1710)
[M::mem_pestat] mean and std.dev: (421.86, 308.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2216)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 234, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 700)
[M::mem_pestat] mean and std.dev: (257.60, 127.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 881)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (487, 1677, 2551)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6679)
[M::mem_pestat] mean and std.dev: (1918.67, 1681.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8743)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (249, 360, 1074)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2724)
[M::mem_pestat] mean and std.dev: (630.67, 662.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3549)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701108 sequences (100000286 bp) in 3.978 CPU sec, 4.368 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 280681, 36, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (280, 455, 1158)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2914)
[M::mem_pestat] mean and std.dev: (713.36, 595.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3792)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 235, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 704)
[M::mem_pestat] mean and std.dev: (259.13, 129.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 886)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (372, 994, 1553)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3915)
[M::mem_pestat] mean and std.dev: (1112.00, 859.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5096)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (232, 280, 501)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1039)
[M::mem_pestat] mean and std.dev: (292.33, 117.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1308)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702028 reads in 232.635 CPU sec, 7.431 real sec
[M::mem_process_seqs] Processed 701554 reads in 166.580 CPU sec, 5.273 real sec
[M::process] read 701028 sequences (100000095 bp) in 3.102 CPU sec, 3.268 real sec...
sorting block 18, #reads = 1072332 mem = 536882048 peak = 871739392
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 280609, 21, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (228, 367, 1989)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5511)
[M::mem_pestat] mean and std.dev: (880.97, 1042.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7272)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 236, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 713)
[M::mem_pestat] mean and std.dev: (260.77, 129.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 898)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (360, 941, 2360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6360)
[M::mem_pestat] mean and std.dev: (1210.29, 1034.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8360)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 297, 550)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1232)
[M::mem_pestat] mean and std.dev: (352.12, 242.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1573)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700396 sequences (100000259 bp) in 4.209 CPU sec, 4.466 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 280853, 17, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (257, 795, 2178)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6020)
[M::mem_pestat] mean and std.dev: (1112.26, 1129.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7941)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 237, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 714)
[M::mem_pestat] mean and std.dev: (261.45, 130.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 899)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1052, 1477, 2329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4883)
[M::mem_pestat] mean and std.dev: (1604.59, 809.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6160)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (354, 536, 844)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1824)
[M::mem_pestat] mean and std.dev: (537.13, 309.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2314)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701108 reads in 226.714 CPU sec, 7.261 real sec
sorting block 19, #reads = 1069679 mem = 536879176 peak = 871739392
[M::mem_process_seqs] Processed 701028 reads in 159.974 CPU sec, 5.076 real sec
[M::process] read 700236 sequences (100000064 bp) in 3.446 CPU sec, 3.629 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 280229, 32, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (143, 512, 1514)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4256)
[M::mem_pestat] mean and std.dev: (1126.78, 1335.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6471)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 238, 345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 715)
[M::mem_pestat] mean and std.dev: (262.27, 130.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 900)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (491, 950, 1348)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3062)
[M::mem_pestat] mean and std.dev: (941.79, 661.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3919)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (241, 400, 1269)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3325)
[M::mem_pestat] mean and std.dev: (687.33, 653.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4353)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 20, #reads = 1071588 mem = 536879760 peak = 871739392
[M::process] read 699886 sequences (100000024 bp) in 3.566 CPU sec, 3.815 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 280436, 19, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 220, 459)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1021)
[M::mem_pestat] mean and std.dev: (346.30, 291.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1511)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 239, 346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 718)
[M::mem_pestat] mean and std.dev: (262.86, 130.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 904)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (534, 534, 1261)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2715)
[M::mem_pestat] mean and std.dev: (737.33, 479.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3442)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 341, 978)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2550)
[M::mem_pestat] mean and std.dev: (550.48, 553.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3336)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700396 reads in 227.272 CPU sec, 7.269 real sec
[M::mem_process_seqs] Processed 700236 reads in 162.886 CPU sec, 5.174 real sec
[M::process] read 699798 sequences (100000066 bp) in 3.348 CPU sec, 3.502 real sec...
sorting block 21, #reads = 1071554 mem = 536877285 peak = 871739392
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 279834, 33, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 382, 1372)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3746)
[M::mem_pestat] mean and std.dev: (723.78, 790.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4933)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 240, 349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 725)
[M::mem_pestat] mean and std.dev: (264.68, 131.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 913)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (391, 760, 1226)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2896)
[M::mem_pestat] mean and std.dev: (742.60, 600.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3731)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 305, 488)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1078)
[M::mem_pestat] mean and std.dev: (378.10, 250.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1381)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699198 sequences (100000269 bp) in 3.969 CPU sec, 4.225 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 279935, 18, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 346, 1324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3550)
[M::mem_pestat] mean and std.dev: (676.78, 784.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4663)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 239, 347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 721)
[M::mem_pestat] mean and std.dev: (263.78, 131.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 908)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (237, 1267, 2499)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7023)
[M::mem_pestat] mean and std.dev: (1345.33, 1209.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9285)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 434, 933)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2357)
[M::mem_pestat] mean and std.dev: (561.58, 499.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3069)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699886 reads in 227.988 CPU sec, 7.260 real sec
[M::process] read 698568 sequences (100000002 bp) in 2.708 CPU sec, 2.772 real sec...
[M::mem_process_seqs] Processed 699798 reads in 162.436 CPU sec, 5.155 real sec
sorting block 22, #reads = 1070092 mem = 536880706 peak = 871739392
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 279745, 17, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (250, 394, 826)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1978)
[M::mem_pestat] mean and std.dev: (549.92, 449.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2554)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 242, 350)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 726)
[M::mem_pestat] mean and std.dev: (265.91, 131.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 914)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (329, 612, 953)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2201)
[M::mem_pestat] mean and std.dev: (480.33, 297.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2825)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 243, 1069)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2827)
[M::mem_pestat] mean and std.dev: (626.15, 662.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3706)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698962 sequences (100000044 bp) in 3.897 CPU sec, 4.121 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 280213, 13, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (274, 527, 622)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1318)
[M::mem_pestat] mean and std.dev: (411.22, 237.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1666)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 243, 352)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 732)
[M::mem_pestat] mean and std.dev: (267.19, 132.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 922)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (684, 1176, 2544)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6264)
[M::mem_pestat] mean and std.dev: (1161.58, 832.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8124)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 326, 561)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1361)
[M::mem_pestat] mean and std.dev: (311.78, 214.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1761)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699198 reads in 229.087 CPU sec, 7.298 real sec
[M::process] read 698494 sequences (100000049 bp) in 2.972 CPU sec, 3.024 real sec...
sorting block 23, #reads = 1069675 mem = 536877864 peak = 871739392
[M::mem_process_seqs] Processed 698568 reads in 163.649 CPU sec, 5.484 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 279390, 24, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 773, 1696)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4660)
[M::mem_pestat] mean and std.dev: (985.85, 1010.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6142)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 240, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 705)
[M::mem_pestat] mean and std.dev: (261.71, 127.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 886)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (360, 1417, 3084)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8532)
[M::mem_pestat] mean and std.dev: (1848.54, 1838.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11256)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 375, 635)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1467)
[M::mem_pestat] mean and std.dev: (427.40, 298.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1883)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 24, #reads = 1069667 mem = 536881998 peak = 890630144
[M::process] read 698626 sequences (100000200 bp) in 3.931 CPU sec, 4.220 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 278657, 21, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 375, 1395)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3829)
[M::mem_pestat] mean and std.dev: (741.82, 912.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5046)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 242, 347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 715)
[M::mem_pestat] mean and std.dev: (264.55, 129.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 899)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (513, 946, 1280)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2814)
[M::mem_pestat] mean and std.dev: (898.05, 565.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3581)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 353, 890)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2288)
[M::mem_pestat] mean and std.dev: (435.36, 348.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2987)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698962 reads in 233.429 CPU sec, 7.717 real sec
[M::process] read 698848 sequences (100000170 bp) in 2.950 CPU sec, 2.992 real sec...
[M::mem_process_seqs] Processed 698494 reads in 166.300 CPU sec, 5.258 real sec
sorting block 25, #reads = 1067412 mem = 536879473 peak = 890630144
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 279376, 32, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 312, 1575)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4411)
[M::mem_pestat] mean and std.dev: (661.75, 844.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5829)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 242, 345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 711)
[M::mem_pestat] mean and std.dev: (263.34, 128.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 894)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (342, 736, 1419)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3573)
[M::mem_pestat] mean and std.dev: (1006.44, 937.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4757)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 413, 729)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1777)
[M::mem_pestat] mean and std.dev: (419.08, 314.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2301)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698614 sequences (100000102 bp) in 3.416 CPU sec, 3.620 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 279737, 46, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 340, 878)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2318)
[M::mem_pestat] mean and std.dev: (546.31, 579.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3038)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 240, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 702)
[M::mem_pestat] mean and std.dev: (261.64, 126.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 882)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (413, 1261, 1705)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4289)
[M::mem_pestat] mean and std.dev: (1117.90, 819.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5581)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (237, 380, 856)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2094)
[M::mem_pestat] mean and std.dev: (523.02, 395.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2713)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698970 sequences (100000257 bp) in 2.680 CPU sec, 2.686 real sec...
[M::mem_process_seqs] Processed 698626 reads in 240.285 CPU sec, 7.806 real sec
[M::mem_process_seqs] Processed 698848 reads in 172.066 CPU sec, 5.509 real sec
sorting block 26, #reads = 1066600 mem = 536883082 peak = 890630144
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 278989, 30, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (238, 840, 1150)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2974)
[M::mem_pestat] mean and std.dev: (716.02, 552.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3886)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 240, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 705)
[M::mem_pestat] mean and std.dev: (262.28, 127.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 886)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (417, 956, 2615)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7011)
[M::mem_pestat] mean and std.dev: (1602.10, 1460.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9209)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 325, 1316)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3500)
[M::mem_pestat] mean and std.dev: (640.37, 701.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4592)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699152 sequences (100000090 bp) in 3.721 CPU sec, 3.975 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 279685, 40, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 351, 1078)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2872)
[M::mem_pestat] mean and std.dev: (618.47, 690.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3769)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 240, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 708)
[M::mem_pestat] mean and std.dev: (263.00, 128.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 890)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (424, 775, 1975)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5077)
[M::mem_pestat] mean and std.dev: (1361.55, 1186.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6628)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 422, 1112)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2996)
[M::mem_pestat] mean and std.dev: (603.08, 517.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3938)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699138 sequences (100000186 bp) in 2.799 CPU sec, 2.794 real sec...
[M::mem_process_seqs] Processed 698614 reads in 236.514 CPU sec, 7.516 real sec
sorting block 27, #reads = 1066880 mem = 536878389 peak = 890630144
[M::mem_process_seqs] Processed 698970 reads in 169.543 CPU sec, 5.661 real sec
sorting block 28, #reads = 1067448 mem = 536880669 peak = 890630144
[M::process] read 698956 sequences (100000029 bp) in 4.006 CPU sec, 4.308 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 279627, 37, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 453, 1243)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3399)
[M::mem_pestat] mean and std.dev: (767.59, 809.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4477)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 239, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 707)
[M::mem_pestat] mean and std.dev: (262.03, 127.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 889)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (232, 820, 1888)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5200)
[M::mem_pestat] mean and std.dev: (1294.49, 1310.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6856)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (300, 404, 973)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2319)
[M::mem_pestat] mean and std.dev: (581.43, 494.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2992)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699138 reads in 141.839 CPU sec, 4.496 real sec
[M::process] read 699386 sequences (100000065 bp) in 3.057 CPU sec, 3.100 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 279529, 17, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 292, 1709)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4785)
[M::mem_pestat] mean and std.dev: (1073.49, 1386.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6618)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 239, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 701)
[M::mem_pestat] mean and std.dev: (260.92, 126.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 881)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (477, 1008, 2135)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5451)
[M::mem_pestat] mean and std.dev: (1255.24, 1086.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7109)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (234, 462, 1185)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3087)
[M::mem_pestat] mean and std.dev: (685.72, 696.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4038)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 279527, 30, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 491, 2069)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5795)
[M::mem_pestat] mean and std.dev: (1105.17, 1313.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7658)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 240, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 708)
[M::mem_pestat] mean and std.dev: (262.59, 128.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 890)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (449, 660, 1345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3137)
[M::mem_pestat] mean and std.dev: (876.11, 773.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4033)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 361, 1097)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2879)
[M::mem_pestat] mean and std.dev: (675.12, 572.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3770)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699152 reads in 383.001 CPU sec, 12.493 real sec
[M::process] read 700218 sequences (100000258 bp) in 3.218 CPU sec, 3.335 real sec...
[M::mem_process_seqs] Processed 698956 reads in 214.412 CPU sec, 6.912 real sec
sorting block 29, #reads = 1066009 mem = 536879062 peak = 890630144
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 279231, 17, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 446, 803)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2111)
[M::mem_pestat] mean and std.dev: (467.91, 427.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2765)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 241, 347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 717)
[M::mem_pestat] mean and std.dev: (264.18, 130.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 902)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (444, 1019, 2601)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6915)
[M::mem_pestat] mean and std.dev: (1544.53, 1334.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9072)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 305, 771)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1897)
[M::mem_pestat] mean and std.dev: (498.50, 450.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2460)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 30, #reads = 1066239 mem = 536882070 peak = 948387840
[M::process] read 704816 sequences (100000300 bp) in 4.160 CPU sec, 4.519 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 279561, 46, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 465, 1139)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2981)
[M::mem_pestat] mean and std.dev: (688.62, 745.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3902)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 238, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 709)
[M::mem_pestat] mean and std.dev: (261.50, 129.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 892)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (351, 1477, 1575)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4023)
[M::mem_pestat] mean and std.dev: (1166.64, 837.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5247)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 271, 534)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1184)
[M::mem_pestat] mean and std.dev: (291.00, 154.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1509)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699386 reads in 253.211 CPU sec, 8.136 real sec
[M::process] read 704672 sequences (100000185 bp) in 2.648 CPU sec, 2.663 real sec...
[M::mem_process_seqs] Processed 700218 reads in 181.776 CPU sec, 5.788 real sec
sorting block 31, #reads = 1064383 mem = 536882515 peak = 948387840
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 281473, 34, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 627, 1181)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3117)
[M::mem_pestat] mean and std.dev: (697.61, 754.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4085)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 225, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 672)
[M::mem_pestat] mean and std.dev: (249.03, 123.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 845)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (342, 698, 1201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2919)
[M::mem_pestat] mean and std.dev: (879.85, 714.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3778)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 874, 2399)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6751)
[M::mem_pestat] mean and std.dev: (1391.22, 1440.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8927)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703990 sequences (100000101 bp) in 3.598 CPU sec, 3.916 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 281774, 25, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 369, 1081)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2905)
[M::mem_pestat] mean and std.dev: (636.42, 647.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3817)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 226, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 678)
[M::mem_pestat] mean and std.dev: (250.41, 124.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 853)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (346, 714, 1643)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4237)
[M::mem_pestat] mean and std.dev: (891.29, 847.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5534)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 235, 878)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2314)
[M::mem_pestat] mean and std.dev: (411.97, 438.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3032)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703694 sequences (100000189 bp) in 2.209 CPU sec, 2.211 real sec...
[M::mem_process_seqs] Processed 704816 reads in 240.910 CPU sec, 7.954 real sec
[M::mem_process_seqs] Processed 704672 reads in 166.574 CPU sec, 5.335 real sec
sorting block 32, #reads = 1068020 mem = 536878344 peak = 948387840
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 281927, 17, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 609, 1398)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3824)
[M::mem_pestat] mean and std.dev: (739.88, 749.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5037)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 228, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 682)
[M::mem_pestat] mean and std.dev: (251.75, 125.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 858)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (593, 985, 1236)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2522)
[M::mem_pestat] mean and std.dev: (823.75, 445.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3165)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 306, 1175)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3085)
[M::mem_pestat] mean and std.dev: (714.45, 844.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4092)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703288 sequences (100000010 bp) in 4.118 CPU sec, 4.416 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 281617, 11, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 389, 686)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1644)
[M::mem_pestat] mean and std.dev: (427.28, 299.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2123)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 229, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 685)
[M::mem_pestat] mean and std.dev: (252.62, 125.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 862)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (967, 1212, 2599)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5863)
[M::mem_pestat] mean and std.dev: (1846.55, 1165.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7495)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 351, 1363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3799)
[M::mem_pestat] mean and std.dev: (913.21, 1055.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5137)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703990 reads in 236.278 CPU sec, 7.602 real sec
[M::process] read 702900 sequences (100000098 bp) in 3.717 CPU sec, 3.934 real sec...
sorting block 33, #reads = 1073092 mem = 536877478 peak = 948387840
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 281596, 24, 23)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (256, 376, 1777)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4819)
[M::mem_pestat] mean and std.dev: (854.98, 933.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6340)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 229, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 688)
[M::mem_pestat] mean and std.dev: (253.41, 126.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 866)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (323, 613, 1661)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4337)
[M::mem_pestat] mean and std.dev: (1114.83, 1048.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5675)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 243, 1648)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4590)
[M::mem_pestat] mean and std.dev: (874.35, 999.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6061)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703288 reads in 135.589 CPU sec, 4.340 real sec
[M::process] read 702080 sequences (100000149 bp) in 2.943 CPU sec, 3.050 real sec...
sorting block 34, #reads = 1071017 mem = 536878500 peak = 948387840
[M::mem_process_seqs] Processed 703694 reads in 387.923 CPU sec, 12.401 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 281354, 29, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (127, 204, 1012)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2782)
[M::mem_pestat] mean and std.dev: (438.02, 502.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3667)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 231, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 698)
[M::mem_pestat] mean and std.dev: (256.13, 128.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 879)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (604, 764, 1492)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3268)
[M::mem_pestat] mean and std.dev: (1021.45, 708.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4156)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (232, 306, 629)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1423)
[M::mem_pestat] mean and std.dev: (363.22, 228.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1820)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 281051, 26, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 407, 1128)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2944)
[M::mem_pestat] mean and std.dev: (796.97, 874.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4296)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 233, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 703)
[M::mem_pestat] mean and std.dev: (258.18, 128.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 885)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 380, 2476)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6996)
[M::mem_pestat] mean and std.dev: (1090.35, 1235.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9256)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 317, 776)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1930)
[M::mem_pestat] mean and std.dev: (482.22, 421.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2507)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702110 sequences (100000130 bp) in 3.920 CPU sec, 4.395 real sec...
[M::mem_process_seqs] Processed 702900 reads in 275.228 CPU sec, 8.811 real sec
[M::mem_process_seqs] Processed 702080 reads in 173.340 CPU sec, 5.553 real sec
sorting block 35, #reads = 1070827 mem = 536886881 peak = 948387840
[M::process] read 701284 sequences (100000229 bp) in 3.926 CPU sec, 4.335 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 280979, 26, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (230, 680, 2105)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5855)
[M::mem_pestat] mean and std.dev: (1122.77, 1126.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7730)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 233, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 702)
[M::mem_pestat] mean and std.dev: (257.34, 128.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 884)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (372, 417, 2350)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6306)
[M::mem_pestat] mean and std.dev: (986.28, 928.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8284)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (248, 321, 1975)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5429)
[M::mem_pestat] mean and std.dev: (823.67, 1076.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7156)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702110 reads in 138.560 CPU sec, 4.602 real sec
[M::process] read 700634 sequences (100000188 bp) in 3.994 CPU sec, 4.327 real sec...
sorting block 36, #reads = 1071051 mem = 536880002 peak = 948387840
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 281080, 34, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 338, 524)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1264)
[M::mem_pestat] mean and std.dev: (392.26, 295.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1634)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 235, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 706)
[M::mem_pestat] mean and std.dev: (259.11, 129.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 889)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (587, 1822, 2985)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7781)
[M::mem_pestat] mean and std.dev: (1903.09, 1495.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10179)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 361, 878)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2230)
[M::mem_pestat] mean and std.dev: (446.62, 424.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2906)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 280503, 14, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (238, 593, 1169)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3031)
[M::mem_pestat] mean and std.dev: (702.25, 708.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3962)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 237, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 714)
[M::mem_pestat] mean and std.dev: (261.81, 130.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 899)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (501, 884, 1504)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3510)
[M::mem_pestat] mean and std.dev: (1015.85, 845.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4513)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 419, 1040)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2718)
[M::mem_pestat] mean and std.dev: (672.21, 643.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3557)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700906 sequences (100000030 bp) in 3.718 CPU sec, 4.003 real sec...
[M::mem_process_seqs] Processed 701284 reads in 279.846 CPU sec, 9.096 real sec
[M::mem_process_seqs] Processed 700634 reads in 176.906 CPU sec, 5.676 real sec
sorting block 37, #reads = 1071141 mem = 536882159 peak = 948387840
[M::process] read 700760 sequences (100000000 bp) in 4.035 CPU sec, 4.332 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 280405, 16, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (134, 294, 1036)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2840)
[M::mem_pestat] mean and std.dev: (544.76, 580.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3742)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 236, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 711)
[M::mem_pestat] mean and std.dev: (261.46, 131.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 895)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (651, 1408, 2255)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5463)
[M::mem_pestat] mean and std.dev: (1404.44, 1014.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7067)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 342, 641)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1531)
[M::mem_pestat] mean and std.dev: (330.36, 248.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1976)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700538 sequences (100000207 bp) in 3.452 CPU sec, 3.704 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 280650, 12, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 299, 795)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2031)
[M::mem_pestat] mean and std.dev: (443.69, 398.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2649)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 237, 345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 717)
[M::mem_pestat] mean and std.dev: (262.42, 131.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 903)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (138, 552, 2561)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7407)
[M::mem_pestat] mean and std.dev: (1113.33, 1393.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9830)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (265, 556, 974)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2392)
[M::mem_pestat] mean and std.dev: (605.46, 434.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3101)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700906 reads in 242.474 CPU sec, 7.778 real sec
sorting block 38, #reads = 1070974 mem = 536881784 peak = 948387840
[M::mem_process_seqs] Processed 700760 reads in 171.890 CPU sec, 5.460 real sec
[M::process] read 700610 sequences (100000231 bp) in 3.257 CPU sec, 3.426 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 280370, 21, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 277, 750)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1928)
[M::mem_pestat] mean and std.dev: (339.83, 304.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2517)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 238, 346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 718)
[M::mem_pestat] mean and std.dev: (262.88, 131.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 904)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (273, 351, 1313)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3393)
[M::mem_pestat] mean and std.dev: (741.86, 656.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4433)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 526, 1136)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2998)
[M::mem_pestat] mean and std.dev: (666.73, 606.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3929)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 39, #reads = 1070194 mem = 536879758 peak = 948387840
[M::process] read 700454 sequences (100000243 bp) in 3.620 CPU sec, 3.857 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 280174, 15, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 380, 861)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2241)
[M::mem_pestat] mean and std.dev: (413.74, 365.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2931)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 237, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 708)
[M::mem_pestat] mean and std.dev: (260.68, 129.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 891)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (641, 680, 1293)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2597)
[M::mem_pestat] mean and std.dev: (882.57, 530.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3249)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 344, 939)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2431)
[M::mem_pestat] mean and std.dev: (553.34, 557.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3177)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700538 reads in 235.001 CPU sec, 7.492 real sec
[M::process] read 700664 sequences (100000056 bp) in 2.736 CPU sec, 2.796 real sec...
[M::mem_process_seqs] Processed 700610 reads in 166.024 CPU sec, 5.430 real sec
sorting block 40, #reads = 1069426 mem = 536885237 peak = 948387840
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 280401, 31, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 318, 972)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2454)
[M::mem_pestat] mean and std.dev: (525.39, 504.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3195)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 235, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 693)
[M::mem_pestat] mean and std.dev: (257.53, 126.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 871)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (495, 1041, 2038)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5124)
[M::mem_pestat] mean and std.dev: (1332.57, 1103.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6667)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 315, 941)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2379)
[M::mem_pestat] mean and std.dev: (649.98, 689.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3410)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699386 sequences (100000225 bp) in 3.610 CPU sec, 3.842 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 280171, 28, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 351, 716)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1712)
[M::mem_pestat] mean and std.dev: (406.54, 290.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2210)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 235, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 696)
[M::mem_pestat] mean and std.dev: (258.33, 127.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 875)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (394, 1228, 2591)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6985)
[M::mem_pestat] mean and std.dev: (1310.42, 1474.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9182)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 326, 457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 949)
[M::mem_pestat] mean and std.dev: (303.51, 128.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1195)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699120 sequences (100000065 bp) in 2.642 CPU sec, 2.651 real sec...
[M::mem_process_seqs] Processed 700454 reads in 240.764 CPU sec, 7.828 real sec
[M::mem_process_seqs] Processed 700664 reads in 166.536 CPU sec, 5.372 real sec
sorting block 41, #reads = 1067873 mem = 536878260 peak = 948387840
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 279784, 31, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 314, 1649)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4547)
[M::mem_pestat] mean and std.dev: (915.92, 1093.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5996)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 241, 347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 719)
[M::mem_pestat] mean and std.dev: (263.90, 130.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 905)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (388, 1403, 1738)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4438)
[M::mem_pestat] mean and std.dev: (1075.75, 850.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5788)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (231, 508, 1211)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3171)
[M::mem_pestat] mean and std.dev: (598.89, 514.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4151)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698950 sequences (100000155 bp) in 3.633 CPU sec, 3.862 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 279743, 7, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (281, 575, 1338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3452)
[M::mem_pestat] mean and std.dev: (803.58, 706.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4509)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 241, 346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 714)
[M::mem_pestat] mean and std.dev: (263.72, 129.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 898)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 376, 803)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2011)
[M::mem_pestat] mean and std.dev: (505.70, 454.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2615)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699386 reads in 237.434 CPU sec, 7.656 real sec
sorting block 42, #reads = 1069010 mem = 536879913 peak = 948387840
[M::process] read 698922 sequences (100000115 bp) in 2.940 CPU sec, 2.969 real sec...
[M::mem_process_seqs] Processed 699120 reads in 171.218 CPU sec, 5.456 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 279489, 28, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 299, 448)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 912)
[M::mem_pestat] mean and std.dev: (321.02, 176.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1144)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 241, 347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 717)
[M::mem_pestat] mean and std.dev: (264.73, 130.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 902)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (483, 1366, 1755)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4299)
[M::mem_pestat] mean and std.dev: (1281.71, 1095.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5664)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 389, 725)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1721)
[M::mem_pestat] mean and std.dev: (405.00, 270.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2219)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 43, #reads = 1068231 mem = 536879109 peak = 948387840
[M::process] read 699156 sequences (100000163 bp) in 3.686 CPU sec, 3.898 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 279589, 32, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (313, 411, 1260)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3154)
[M::mem_pestat] mean and std.dev: (766.30, 777.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4101)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 241, 346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 714)
[M::mem_pestat] mean and std.dev: (263.96, 129.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 898)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (298, 519, 1533)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4003)
[M::mem_pestat] mean and std.dev: (920.77, 919.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5238)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 292, 1189)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3185)
[M::mem_pestat] mean and std.dev: (665.03, 814.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4183)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698950 reads in 248.597 CPU sec, 8.095 real sec
[M::process] read 699094 sequences (100000131 bp) in 2.945 CPU sec, 2.990 real sec...
[M::mem_process_seqs] Processed 698922 reads in 175.406 CPU sec, 5.580 real sec
sorting block 44, #reads = 1067384 mem = 536888930 peak = 948387840
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 279384, 37, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 360, 1259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3335)
[M::mem_pestat] mean and std.dev: (666.27, 685.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4373)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 240, 346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 716)
[M::mem_pestat] mean and std.dev: (263.53, 129.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 901)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (529, 1044, 1489)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3409)
[M::mem_pestat] mean and std.dev: (1029.88, 846.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4417)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 320, 514)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1116)
[M::mem_pestat] mean and std.dev: (371.23, 246.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1417)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699742 sequences (100000296 bp) in 4.000 CPU sec, 4.276 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 279697, 38, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 421, 1031)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2767)
[M::mem_pestat] mean and std.dev: (558.65, 546.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3635)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 240, 346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 716)
[M::mem_pestat] mean and std.dev: (263.56, 129.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 901)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 604, 1410)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3882)
[M::mem_pestat] mean and std.dev: (887.89, 900.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5118)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (243, 477, 1454)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3876)
[M::mem_pestat] mean and std.dev: (784.89, 768.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5087)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699156 reads in 250.359 CPU sec, 8.006 real sec
[M::process] read 698474 sequences (100000044 bp) in 2.792 CPU sec, 2.830 real sec...
[M::mem_process_seqs] Processed 699094 reads in 179.424 CPU sec, 5.727 real sec
sorting block 45, #reads = 1066703 mem = 536879587 peak = 948387840
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 280414, 28, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 328, 1409)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3825)
[M::mem_pestat] mean and std.dev: (758.89, 812.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5033)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 239, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 712)
[M::mem_pestat] mean and std.dev: (262.24, 129.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 896)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (341, 833, 2397)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6509)
[M::mem_pestat] mean and std.dev: (1064.72, 951.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8565)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (236, 354, 959)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2405)
[M::mem_pestat] mean and std.dev: (476.70, 415.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3128)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703000 sequences (100000244 bp) in 4.164 CPU sec, 4.433 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 279744, 32, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (233, 388, 830)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2024)
[M::mem_pestat] mean and std.dev: (426.42, 339.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2621)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 243, 352)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 730)
[M::mem_pestat] mean and std.dev: (267.60, 133.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 919)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (112, 819, 2371)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6889)
[M::mem_pestat] mean and std.dev: (1164.91, 1376.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9148)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 465, 746)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1876)
[M::mem_pestat] mean and std.dev: (438.14, 345.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2441)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699742 reads in 252.766 CPU sec, 8.112 real sec
sorting block 46, #reads = 1066465 mem = 536882427 peak = 948387840
[M::process] read 704014 sequences (100000071 bp) in 2.743 CPU sec, 2.812 real sec...
[M::mem_process_seqs] Processed 698474 reads in 182.251 CPU sec, 6.004 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 280487, 28, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 450, 649)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1527)
[M::mem_pestat] mean and std.dev: (366.83, 243.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1966)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 230, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 689)
[M::mem_pestat] mean and std.dev: (254.14, 126.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 867)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (314, 599, 1537)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3983)
[M::mem_pestat] mean and std.dev: (610.57, 459.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5206)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 281, 781)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1983)
[M::mem_pestat] mean and std.dev: (486.37, 459.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2584)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 47, #reads = 1066409 mem = 536884180 peak = 948387840
[M::process] read 703694 sequences (100000222 bp) in 3.885 CPU sec, 4.225 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 281818, 31, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (255, 463, 1223)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3159)
[M::mem_pestat] mean and std.dev: (599.73, 543.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4127)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 227, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 679)
[M::mem_pestat] mean and std.dev: (251.31, 124.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 854)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (465, 1453, 2873)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7689)
[M::mem_pestat] mean and std.dev: (1782.58, 1672.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10097)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 272, 580)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1392)
[M::mem_pestat] mean and std.dev: (342.44, 283.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1798)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703200 sequences (100000218 bp) in 2.527 CPU sec, 2.529 real sec...
[M::mem_process_seqs] Processed 703000 reads in 248.491 CPU sec, 8.142 real sec
[M::mem_process_seqs] Processed 704014 reads in 170.529 CPU sec, 5.519 real sec
sorting block 48, #reads = 1068313 mem = 536877864 peak = 948387840
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 281783, 15, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (119, 224, 570)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1472)
[M::mem_pestat] mean and std.dev: (337.83, 314.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1923)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 228, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 682)
[M::mem_pestat] mean and std.dev: (252.11, 124.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 858)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 541, 1286)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3480)
[M::mem_pestat] mean and std.dev: (673.64, 573.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4577)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 311, 426)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 976)
[M::mem_pestat] mean and std.dev: (248.03, 122.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1251)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703270 sequences (100000187 bp) in 3.976 CPU sec, 4.359 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 281435, 21, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 447, 1085)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2817)
[M::mem_pestat] mean and std.dev: (590.04, 529.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3683)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 230, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 683)
[M::mem_pestat] mean and std.dev: (252.92, 124.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 859)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (554, 852, 2064)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5084)
[M::mem_pestat] mean and std.dev: (976.11, 956.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6594)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (231, 325, 566)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1236)
[M::mem_pestat] mean and std.dev: (348.49, 190.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1571)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703694 reads in 236.158 CPU sec, 7.665 real sec
[M::process] read 703784 sequences (100000080 bp) in 3.558 CPU sec, 3.801 real sec...
sorting block 49, #reads = 1073510 mem = 536876513 peak = 948387840
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 281790, 19, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 474, 1526)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4140)
[M::mem_pestat] mean and std.dev: (860.55, 979.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5447)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 230, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 689)
[M::mem_pestat] mean and std.dev: (254.30, 126.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 867)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (509, 1219, 1674)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4004)
[M::mem_pestat] mean and std.dev: (1237.28, 961.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5169)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 729, 2125)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5955)
[M::mem_pestat] mean and std.dev: (1173.04, 1131.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7870)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703270 reads in 134.792 CPU sec, 4.288 real sec
[M::process] read 702794 sequences (100000249 bp) in 3.002 CPU sec, 3.093 real sec...
[M::mem_process_seqs] Processed 703200 reads in 380.126 CPU sec, 12.123 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 281441, 38, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 403, 593)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1379)
[M::mem_pestat] mean and std.dev: (417.94, 284.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1772)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 228, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 682)
[M::mem_pestat] mean and std.dev: (252.06, 125.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 858)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (128, 720, 1192)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3320)
[M::mem_pestat] mean and std.dev: (795.37, 799.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4384)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (250, 301, 985)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2455)
[M::mem_pestat] mean and std.dev: (510.92, 408.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3190)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 50, #reads = 1073036 mem = 536880322 peak = 948387840
[M::process] read 702908 sequences (100000173 bp) in 3.606 CPU sec, 3.855 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 281595, 21, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (254, 349, 816)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1940)
[M::mem_pestat] mean and std.dev: (459.63, 322.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2502)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 231, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 693)
[M::mem_pestat] mean and std.dev: (255.65, 127.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 872)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 544, 1803)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5021)
[M::mem_pestat] mean and std.dev: (959.24, 844.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6630)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 481, 1498)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4124)
[M::mem_pestat] mean and std.dev: (735.84, 720.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5437)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703784 reads in 269.536 CPU sec, 8.586 real sec
[M::mem_process_seqs] Processed 702794 reads in 169.859 CPU sec, 5.402 real sec
[M::process] read 702590 sequences (100000169 bp) in 3.887 CPU sec, 4.223 real sec...
sorting block 51, #reads = 1072538 mem = 536878430 peak = 948387840
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 280942, 15, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (250, 726, 1757)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4771)
[M::mem_pestat] mean and std.dev: (991.45, 958.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6278)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 231, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 693)
[M::mem_pestat] mean and std.dev: (255.52, 127.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 872)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 790, 2446)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6908)
[M::mem_pestat] mean and std.dev: (1508.27, 1928.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9221)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 238, 765)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1961)
[M::mem_pestat] mean and std.dev: (304.45, 233.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2559)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 281201, 20, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (243, 440, 877)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2145)
[M::mem_pestat] mean and std.dev: (470.58, 292.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2779)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 231, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 696)
[M::mem_pestat] mean and std.dev: (256.33, 128.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 876)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (317, 633, 817)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1817)
[M::mem_pestat] mean and std.dev: (481.78, 317.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2317)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 291, 1689)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4675)
[M::mem_pestat] mean and std.dev: (952.46, 1106.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6168)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702210 sequences (100000070 bp) in 4.397 CPU sec, 4.751 real sec...
[M::mem_process_seqs] Processed 702908 reads in 240.739 CPU sec, 7.789 real sec
[M::mem_process_seqs] Processed 702590 reads in 166.470 CPU sec, 5.327 real sec
sorting block 52, #reads = 1071238 mem = 536881352 peak = 948387840
[M::process] read 701340 sequences (100000049 bp) in 3.670 CPU sec, 4.148 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 280666, 24, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 308, 505)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1177)
[M::mem_pestat] mean and std.dev: (308.51, 201.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1513)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 233, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 702)
[M::mem_pestat] mean and std.dev: (257.71, 128.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 884)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (525, 1294, 2272)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5766)
[M::mem_pestat] mean and std.dev: (1549.96, 1207.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7513)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 356, 855)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2145)
[M::mem_pestat] mean and std.dev: (506.76, 442.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2790)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702210 reads in 134.940 CPU sec, 4.447 real sec
sorting block 53, #reads = 1072208 mem = 536885879 peak = 948387840
[M::process] read 701384 sequences (100000192 bp) in 3.611 CPU sec, 3.923 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 280651, 36, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (294, 518, 1188)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2976)
[M::mem_pestat] mean and std.dev: (659.82, 531.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3870)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 235, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 704)
[M::mem_pestat] mean and std.dev: (259.22, 129.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 886)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (349, 863, 4712)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13438)
[M::mem_pestat] mean and std.dev: (2207.11, 2424.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17801)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (285, 328, 645)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1365)
[M::mem_pestat] mean and std.dev: (389.97, 204.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1725)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701638 sequences (100000235 bp) in 3.482 CPU sec, 3.738 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 280283, 29, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (352, 1053, 1685)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4351)
[M::mem_pestat] mean and std.dev: (1101.38, 919.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5684)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 235, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 710)
[M::mem_pestat] mean and std.dev: (260.27, 130.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 894)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 1047, 1232)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3300)
[M::mem_pestat] mean and std.dev: (930.26, 794.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4334)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 442, 1461)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3981)
[M::mem_pestat] mean and std.dev: (689.92, 696.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5241)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701340 reads in 269.708 CPU sec, 8.697 real sec
sorting block 54, #reads = 1072113 mem = 536880156 peak = 952201216
[M::mem_process_seqs] Processed 701384 reads in 169.575 CPU sec, 5.387 real sec
[M::process] read 700930 sequences (100000143 bp) in 3.406 CPU sec, 3.632 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 281469, 33, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 288, 489)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1129)
[M::mem_pestat] mean and std.dev: (348.49, 284.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1488)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 235, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 712)
[M::mem_pestat] mean and std.dev: (260.25, 130.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 897)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (431, 539, 1558)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3812)
[M::mem_pestat] mean and std.dev: (881.62, 877.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4939)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (246, 545, 3239)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9225)
[M::mem_pestat] mean and std.dev: (1811.38, 2413.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12218)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 55, #reads = 1069470 mem = 536876641 peak = 952201216
[M::process] read 700732 sequences (100000158 bp) in 3.841 CPU sec, 4.133 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 280367, 32, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (146, 256, 540)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1328)
[M::mem_pestat] mean and std.dev: (329.25, 277.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1722)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 236, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 714)
[M::mem_pestat] mean and std.dev: (261.35, 131.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 899)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 737, 2096)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5962)
[M::mem_pestat] mean and std.dev: (1141.97, 1136.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7895)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (250, 449, 740)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1720)
[M::mem_pestat] mean and std.dev: (417.86, 247.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2210)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701638 reads in 234.029 CPU sec, 7.517 real sec
[M::mem_process_seqs] Processed 700930 reads in 167.928 CPU sec, 5.339 real sec
[M::process] read 700206 sequences (100000112 bp) in 4.179 CPU sec, 4.548 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 280911, 22, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 423, 786)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1994)
[M::mem_pestat] mean and std.dev: (445.55, 331.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2598)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 238, 345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 717)
[M::mem_pestat] mean and std.dev: (262.37, 130.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 903)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (326, 917, 1187)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2909)
[M::mem_pestat] mean and std.dev: (686.00, 438.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3770)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 375, 925)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2421)
[M::mem_pestat] mean and std.dev: (435.00, 402.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3169)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 56, #reads = 1070749 mem = 536877049 peak = 952201216
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 279895, 46, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (290, 379, 1240)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3140)
[M::mem_pestat] mean and std.dev: (641.66, 605.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4090)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 238, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 712)
[M::mem_pestat] mean and std.dev: (261.97, 129.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 896)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (604, 842, 1477)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3223)
[M::mem_pestat] mean and std.dev: (855.75, 581.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4096)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (296, 378, 998)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2402)
[M::mem_pestat] mean and std.dev: (616.61, 531.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3104)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699448 sequences (100000252 bp) in 3.625 CPU sec, 3.885 real sec...
[M::mem_process_seqs] Processed 700732 reads in 239.057 CPU sec, 7.780 real sec
[M::mem_process_seqs] Processed 700206 reads in 172.435 CPU sec, 5.557 real sec
sorting block 57, #reads = 1070940 mem = 536878948 peak = 957173760
[M::process] read 699288 sequences (100000279 bp) in 4.029 CPU sec, 4.328 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 280406, 24, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 384, 968)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2466)
[M::mem_pestat] mean and std.dev: (465.93, 371.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3215)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 240, 347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 719)
[M::mem_pestat] mean and std.dev: (264.13, 130.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 905)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (595, 734, 1988)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4774)
[M::mem_pestat] mean and std.dev: (1396.42, 1365.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6858)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (247, 415, 1667)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4507)
[M::mem_pestat] mean and std.dev: (946.08, 1006.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5927)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698604 sequences (100000256 bp) in 3.666 CPU sec, 3.934 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 279984, 17, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 544, 1291)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3533)
[M::mem_pestat] mean and std.dev: (696.96, 749.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4654)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 241, 348)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 722)
[M::mem_pestat] mean and std.dev: (264.92, 131.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 909)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (493, 931, 2630)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6904)
[M::mem_pestat] mean and std.dev: (1347.00, 1234.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9041)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (233, 349, 830)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2024)
[M::mem_pestat] mean and std.dev: (412.09, 322.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2621)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699448 reads in 243.540 CPU sec, 7.802 real sec
[M::mem_process_seqs] Processed 699288 reads in 174.713 CPU sec, 5.557 real sec
sorting block 58, #reads = 1068721 mem = 536879231 peak = 957173760
[M::process] read 698576 sequences (100000225 bp) in 3.553 CPU sec, 3.765 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 279998, 27, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (251, 563, 1254)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3260)
[M::mem_pestat] mean and std.dev: (678.75, 510.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4263)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 243, 350)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 726)
[M::mem_pestat] mean and std.dev: (266.19, 131.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 914)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (860, 1525, 7410)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 20510)
[M::mem_pestat] mean and std.dev: (3085.70, 3143.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 27060)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 279, 1173)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3197)
[M::mem_pestat] mean and std.dev: (627.05, 687.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4209)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 59, #reads = 1068085 mem = 536884671 peak = 1018798080
[M::process] read 698164 sequences (100000245 bp) in 4.479 CPU sec, 4.855 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 279154, 20, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 424, 1119)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2917)
[M::mem_pestat] mean and std.dev: (781.06, 728.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3816)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 243, 348)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 718)
[M::mem_pestat] mean and std.dev: (264.96, 129.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 903)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (82, 364, 1897)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5527)
[M::mem_pestat] mean and std.dev: (653.95, 788.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7342)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (239, 400, 1004)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2534)
[M::mem_pestat] mean and std.dev: (632.46, 556.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3299)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698604 reads in 239.014 CPU sec, 7.661 real sec
[M::mem_process_seqs] Processed 698576 reads in 173.807 CPU sec, 5.541 real sec
[M::process] read 698204 sequences (100000130 bp) in 3.260 CPU sec, 3.487 real sec...
sorting block 60, #reads = 1067834 mem = 536878629 peak = 1018798080
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 279344, 28, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 691, 2167)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6147)
[M::mem_pestat] mean and std.dev: (1180.95, 1327.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8137)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 244, 350)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 724)
[M::mem_pestat] mean and std.dev: (266.85, 131.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 911)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 751, 1277)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3511)
[M::mem_pestat] mean and std.dev: (886.50, 942.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4657)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (236, 326, 976)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2456)
[M::mem_pestat] mean and std.dev: (618.12, 651.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3226)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698440 sequences (100000192 bp) in 3.676 CPU sec, 3.958 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 278762, 18, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (136, 226, 618)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1582)
[M::mem_pestat] mean and std.dev: (394.02, 403.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2064)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 243, 348)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 718)
[M::mem_pestat] mean and std.dev: (265.39, 129.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 903)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 567, 720)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1744)
[M::mem_pestat] mean and std.dev: (443.50, 250.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2256)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 296, 1165)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3061)
[M::mem_pestat] mean and std.dev: (677.48, 720.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4009)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698164 reads in 242.264 CPU sec, 7.720 real sec
[M::process] read 698470 sequences (100000244 bp) in 2.521 CPU sec, 2.560 real sec...
[M::mem_process_seqs] Processed 698204 reads in 174.015 CPU sec, 5.671 real sec
sorting block 61, #reads = 1066252 mem = 536885316 peak = 1018798080
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 279195, 20, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 885, 2301)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6565)
[M::mem_pestat] mean and std.dev: (1328.15, 1378.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8697)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 242, 347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 715)
[M::mem_pestat] mean and std.dev: (264.41, 129.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 899)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (525, 1238, 1483)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3399)
[M::mem_pestat] mean and std.dev: (1197.75, 916.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4865)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 349, 1702)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4732)
[M::mem_pestat] mean and std.dev: (704.46, 935.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6247)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698382 sequences (100000081 bp) in 3.827 CPU sec, 4.097 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 279107, 27, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 329, 817)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2097)
[M::mem_pestat] mean and std.dev: (399.24, 318.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2737)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 242, 346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 714)
[M::mem_pestat] mean and std.dev: (263.96, 128.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 898)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 815, 1929)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5361)
[M::mem_pestat] mean and std.dev: (1087.04, 1160.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7077)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 315, 1096)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2976)
[M::mem_pestat] mean and std.dev: (490.97, 499.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3916)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698440 reads in 248.048 CPU sec, 8.041 real sec
[M::process] read 707256 sequences (100000113 bp) in 2.621 CPU sec, 2.624 real sec...
sorting block 62, #reads = 1065279 mem = 536879381 peak = 1018798080
[M::mem_process_seqs] Processed 698470 reads in 183.699 CPU sec, 5.883 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 279257, 26, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (240, 429, 681)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1563)
[M::mem_pestat] mean and std.dev: (393.44, 217.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2004)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 243, 348)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 718)
[M::mem_pestat] mean and std.dev: (265.53, 130.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 903)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (393, 1577, 2283)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6063)
[M::mem_pestat] mean and std.dev: (1371.88, 933.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7953)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 275, 1055)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2731)
[M::mem_pestat] mean and std.dev: (670.95, 846.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4056)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 63, #reads = 1065999 mem = 536879475 peak = 1018798080
[M::process] read 707048 sequences (100000029 bp) in 3.383 CPU sec, 3.561 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 281948, 23, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 277, 691)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1711)
[M::mem_pestat] mean and std.dev: (402.70, 310.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2221)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 217, 313)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 641)
[M::mem_pestat] mean and std.dev: (240.54, 118.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 805)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (301, 692, 1133)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2797)
[M::mem_pestat] mean and std.dev: (594.37, 440.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3629)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 489, 1009)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2707)
[M::mem_pestat] mean and std.dev: (620.12, 647.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3556)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706812 sequences (100000075 bp) in 2.665 CPU sec, 2.670 real sec...
[M::mem_process_seqs] Processed 698382 reads in 261.222 CPU sec, 8.348 real sec
[M::mem_process_seqs] Processed 707256 reads in 192.029 CPU sec, 6.139 real sec
sorting block 64, #reads = 1063143 mem = 536878087 peak = 1018798080
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 283199, 22, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 309, 1101)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2961)
[M::mem_pestat] mean and std.dev: (596.35, 635.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3891)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 218, 316)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 650)
[M::mem_pestat] mean and std.dev: (243.20, 121.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 817)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (712, 1319, 3664)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9568)
[M::mem_pestat] mean and std.dev: (2210.71, 2142.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12520)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 319, 1657)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4595)
[M::mem_pestat] mean and std.dev: (859.32, 1014.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6064)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705826 sequences (100000183 bp) in 3.585 CPU sec, 3.804 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 282730, 25, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 291, 724)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1876)
[M::mem_pestat] mean and std.dev: (381.31, 305.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2452)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 219, 317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 651)
[M::mem_pestat] mean and std.dev: (243.56, 121.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 818)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (272, 459, 945)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2291)
[M::mem_pestat] mean and std.dev: (683.40, 549.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2964)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 347, 894)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2244)
[M::mem_pestat] mean and std.dev: (422.59, 332.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2919)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703880 sequences (100000290 bp) in 2.762 CPU sec, 2.769 real sec...
[M::mem_process_seqs] Processed 707048 reads in 257.335 CPU sec, 8.212 real sec
[M::mem_process_seqs] Processed 706812 reads in 181.424 CPU sec, 5.787 real sec
sorting block 65, #reads = 1068572 mem = 536879115 peak = 1018798080
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 282198, 23, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (247, 637, 854)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2068)
[M::mem_pestat] mean and std.dev: (567.20, 398.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2675)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 222, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 661)
[M::mem_pestat] mean and std.dev: (246.53, 123.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 831)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 633, 1128)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2986)
[M::mem_pestat] mean and std.dev: (725.23, 638.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3915)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 385, 2559)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7229)
[M::mem_pestat] mean and std.dev: (1211.63, 1449.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9564)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703618 sequences (100000187 bp) in 3.353 CPU sec, 3.555 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 282492, 20, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 245, 570)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1348)
[M::mem_pestat] mean and std.dev: (345.33, 264.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1737)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 226, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 679)
[M::mem_pestat] mean and std.dev: (251.73, 125.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 854)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (380, 970, 4054)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 11402)
[M::mem_pestat] mean and std.dev: (2099.50, 2196.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 15076)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 297, 1137)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2999)
[M::mem_pestat] mean and std.dev: (618.71, 628.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3930)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702730 sequences (100000085 bp) in 2.874 CPU sec, 2.878 real sec...
[M::mem_process_seqs] Processed 705826 reads in 254.042 CPU sec, 8.161 real sec
sorting block 66, #reads = 1068966 mem = 536880305 peak = 1018798080
[M::mem_process_seqs] Processed 703880 reads in 170.288 CPU sec, 5.469 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 282236, 17, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (297, 430, 818)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1860)
[M::mem_pestat] mean and std.dev: (474.63, 278.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2381)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 228, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 694)
[M::mem_pestat] mean and std.dev: (254.41, 128.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 874)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (228, 719, 2073)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5763)
[M::mem_pestat] mean and std.dev: (1243.76, 1523.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7608)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 320, 1219)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3271)
[M::mem_pestat] mean and std.dev: (723.93, 749.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4297)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 67, #reads = 1070587 mem = 536878386 peak = 1073364992
[M::process] read 702138 sequences (100000136 bp) in 3.608 CPU sec, 3.854 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 281737, 20, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 473, 946)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2504)
[M::mem_pestat] mean and std.dev: (522.87, 486.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3283)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 230, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 698)
[M::mem_pestat] mean and std.dev: (256.03, 128.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 879)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (283, 939, 3137)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8845)
[M::mem_pestat] mean and std.dev: (1796.20, 2125.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11699)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (243, 355, 984)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2466)
[M::mem_pestat] mean and std.dev: (404.03, 359.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3207)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702234 sequences (100000253 bp) in 2.279 CPU sec, 2.282 real sec...
[M::mem_process_seqs] Processed 703618 reads in 248.809 CPU sec, 7.991 real sec
[M::mem_process_seqs] Processed 702730 reads in 171.094 CPU sec, 5.558 real sec
sorting block 68, #reads = 1071496 mem = 536879833 peak = 1073364992
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 281600, 18, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 450, 873)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2219)
[M::mem_pestat] mean and std.dev: (627.90, 552.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2892)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 232, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 705)
[M::mem_pestat] mean and std.dev: (258.49, 130.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 888)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1008, 1573, 2096)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4272)
[M::mem_pestat] mean and std.dev: (1442.88, 958.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5360)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 295, 666)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1556)
[M::mem_pestat] mean and std.dev: (338.51, 225.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2001)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701982 sequences (100000179 bp) in 4.293 CPU sec, 4.573 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 281083, 25, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 374, 1077)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2807)
[M::mem_pestat] mean and std.dev: (493.94, 457.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3672)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 231, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 705)
[M::mem_pestat] mean and std.dev: (257.92, 130.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 888)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (40, 739, 2384)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7072)
[M::mem_pestat] mean and std.dev: (1405.16, 1868.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9416)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 356, 2251)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6333)
[M::mem_pestat] mean and std.dev: (988.86, 1016.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8374)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702138 reads in 248.426 CPU sec, 8.017 real sec
[M::process] read 701542 sequences (100000181 bp) in 3.040 CPU sec, 3.082 real sec...
[M::mem_process_seqs] Processed 702234 reads in 177.523 CPU sec, 5.656 real sec
sorting block 69, #reads = 1070117 mem = 536885018 peak = 1073364992
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 281109, 22, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (225, 420, 2533)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7149)
[M::mem_pestat] mean and std.dev: (1350.25, 1557.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9457)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 233, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 709)
[M::mem_pestat] mean and std.dev: (259.83, 131.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 893)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (114, 364, 664)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1764)
[M::mem_pestat] mean and std.dev: (293.11, 239.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2314)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 333, 1933)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5409)
[M::mem_pestat] mean and std.dev: (916.37, 1005.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7147)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702066 sequences (100000297 bp) in 3.538 CPU sec, 3.829 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 280682, 39, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (139, 288, 689)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1789)
[M::mem_pestat] mean and std.dev: (356.88, 350.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2339)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 234, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 718)
[M::mem_pestat] mean and std.dev: (261.13, 132.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 905)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (281, 675, 1548)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4082)
[M::mem_pestat] mean and std.dev: (789.89, 717.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5349)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 295, 971)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2597)
[M::mem_pestat] mean and std.dev: (388.38, 372.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3410)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700554 sequences (100000189 bp) in 2.833 CPU sec, 2.836 real sec...
[M::mem_process_seqs] Processed 701982 reads in 256.811 CPU sec, 8.245 real sec
[M::mem_process_seqs] Processed 701542 reads in 177.083 CPU sec, 5.726 real sec
sorting block 70, #reads = 1068628 mem = 536880402 peak = 1073364992
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 280941, 27, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 264, 516)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1124)
[M::mem_pestat] mean and std.dev: (265.61, 136.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1428)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 233, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 709)
[M::mem_pestat] mean and std.dev: (259.45, 131.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 893)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (270, 853, 2197)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6051)
[M::mem_pestat] mean and std.dev: (937.91, 784.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7978)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 219, 681)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1673)
[M::mem_pestat] mean and std.dev: (379.93, 374.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2169)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 71, #reads = 1067944 mem = 536880416 peak = 1073364992
[M::process] read 700232 sequences (100000169 bp) in 4.186 CPU sec, 4.461 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 279775, 29, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 378, 1413)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3875)
[M::mem_pestat] mean and std.dev: (820.31, 925.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5106)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 236, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 708)
[M::mem_pestat] mean and std.dev: (260.99, 130.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 891)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (320, 1235, 4880)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 14000)
[M::mem_pestat] mean and std.dev: (2465.17, 3138.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 18560)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 319, 1088)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2822)
[M::mem_pestat] mean and std.dev: (616.52, 679.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3689)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699628 sequences (100000126 bp) in 2.854 CPU sec, 2.860 real sec...
[M::mem_process_seqs] Processed 702066 reads in 263.537 CPU sec, 8.493 real sec
[M::mem_process_seqs] Processed 700554 reads in 188.037 CPU sec, 5.993 real sec
sorting block 72, #reads = 1066667 mem = 536881136 peak = 1073364992
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 279770, 24, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 322, 845)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2239)
[M::mem_pestat] mean and std.dev: (570.30, 595.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2952)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 235, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 705)
[M::mem_pestat] mean and std.dev: (260.58, 129.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 887)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (318, 827, 3316)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9312)
[M::mem_pestat] mean and std.dev: (1756.46, 2202.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12310)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (253, 498, 1318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3448)
[M::mem_pestat] mean and std.dev: (664.95, 595.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4513)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699356 sequences (100000291 bp) in 4.011 CPU sec, 4.297 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 279567, 21, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 332, 1289)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3447)
[M::mem_pestat] mean and std.dev: (625.10, 672.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4526)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 237, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 712)
[M::mem_pestat] mean and std.dev: (262.41, 130.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 896)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (245, 467, 2334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6512)
[M::mem_pestat] mean and std.dev: (859.37, 897.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8601)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (311, 407, 874)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2000)
[M::mem_pestat] mean and std.dev: (514.31, 333.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2563)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699892 sequences (100000098 bp) in 2.457 CPU sec, 2.465 real sec...
[M::mem_process_seqs] Processed 700232 reads in 265.508 CPU sec, 8.498 real sec
[M::mem_process_seqs] Processed 699628 reads in 188.225 CPU sec, 6.018 real sec
sorting block 73, #reads = 1063921 mem = 536881067 peak = 1073364992
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 280156, 31, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 354, 1165)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3111)
[M::mem_pestat] mean and std.dev: (714.70, 754.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4084)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 238, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 710)
[M::mem_pestat] mean and std.dev: (262.64, 130.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 893)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (582, 1185, 1637)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3747)
[M::mem_pestat] mean and std.dev: (1056.36, 629.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4802)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 347, 755)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1819)
[M::mem_pestat] mean and std.dev: (432.31, 339.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2351)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700188 sequences (100000105 bp) in 3.950 CPU sec, 4.188 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 279789, 41, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (263, 439, 1039)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2591)
[M::mem_pestat] mean and std.dev: (596.88, 535.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3367)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 237, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 712)
[M::mem_pestat] mean and std.dev: (262.02, 130.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 896)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (379, 707, 1483)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3691)
[M::mem_pestat] mean and std.dev: (922.74, 742.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4795)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 337, 1430)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3912)
[M::mem_pestat] mean and std.dev: (868.49, 995.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5153)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700730 sequences (100000033 bp) in 2.420 CPU sec, 2.427 real sec...
[M::mem_process_seqs] Processed 699356 reads in 259.349 CPU sec, 8.296 real sec
sorting block 74, #reads = 1064911 mem = 536878716 peak = 1073364992
[M::mem_process_seqs] Processed 699892 reads in 185.321 CPU sec, 5.932 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 279866, 25, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 584, 1538)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4228)
[M::mem_pestat] mean and std.dev: (742.20, 856.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5573)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 236, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 705)
[M::mem_pestat] mean and std.dev: (260.29, 129.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 887)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (695, 1304, 1705)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3725)
[M::mem_pestat] mean and std.dev: (1037.32, 642.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4735)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 295, 508)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1164)
[M::mem_pestat] mean and std.dev: (309.52, 202.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1492)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 75, #reads = 1065155 mem = 536878931 peak = 1073364992
[M::process] read 700534 sequences (100000187 bp) in 3.689 CPU sec, 3.857 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 280147, 25, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 481, 1603)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4361)
[M::mem_pestat] mean and std.dev: (716.87, 792.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5740)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 234, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 701)
[M::mem_pestat] mean and std.dev: (258.98, 128.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 882)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (236, 607, 1210)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3158)
[M::mem_pestat] mean and std.dev: (824.12, 671.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4132)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (289, 394, 1247)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3163)
[M::mem_pestat] mean and std.dev: (661.39, 619.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4121)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699830 sequences (100000001 bp) in 2.586 CPU sec, 2.591 real sec...
[M::mem_process_seqs] Processed 700188 reads in 256.277 CPU sec, 8.181 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 279673, 25, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (240, 332, 1014)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2562)
[M::mem_pestat] mean and std.dev: (674.61, 637.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3336)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 234, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 699)
[M::mem_pestat] mean and std.dev: (259.20, 128.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 879)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (686, 1228, 1697)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3719)
[M::mem_pestat] mean and std.dev: (1206.00, 879.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4730)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 277, 640)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1470)
[M::mem_pestat] mean and std.dev: (348.04, 251.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1885)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699912 sequences (100000033 bp) in 3.341 CPU sec, 3.351 real sec...
[M::mem_process_seqs] Processed 700534 reads in 149.984 CPU sec, 5.052 real sec
sorting block 76, #reads = 1064318 mem = 536887418 peak = 1073364992
[M::mem_process_seqs] Processed 700730 reads in 384.365 CPU sec, 12.539 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 279835, 25, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 340, 863)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2165)
[M::mem_pestat] mean and std.dev: (527.69, 458.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2816)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 236, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 706)
[M::mem_pestat] mean and std.dev: (260.93, 129.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 888)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (666, 1408, 6117)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 17019)
[M::mem_pestat] mean and std.dev: (2711.00, 2674.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 22470)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 335, 745)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1883)
[M::mem_pestat] mean and std.dev: (478.79, 471.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2452)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 77, #reads = 1064579 mem = 536877389 peak = 1073364992
[M::process] read 699888 sequences (100000161 bp) in 3.714 CPU sec, 4.089 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 280146, 26, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (291, 641, 1106)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2736)
[M::mem_pestat] mean and std.dev: (746.16, 658.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3551)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 237, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 706)
[M::mem_pestat] mean and std.dev: (261.06, 129.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 888)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (364, 1614, 2275)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6097)
[M::mem_pestat] mean and std.dev: (1451.04, 978.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8008)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 315, 980)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2528)
[M::mem_pestat] mean and std.dev: (570.24, 538.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3302)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699830 reads in 286.254 CPU sec, 9.105 real sec
[M::mem_process_seqs] Processed 699912 reads in 180.480 CPU sec, 5.716 real sec
[M::process] read 706522 sequences (100000154 bp) in 3.449 CPU sec, 3.567 real sec...
sorting block 78, #reads = 1062470 mem = 536878278 peak = 1073364992
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 279489, 23, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 302, 602)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1478)
[M::mem_pestat] mean and std.dev: (330.27, 285.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1916)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 236, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 703)
[M::mem_pestat] mean and std.dev: (260.63, 128.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 884)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 736, 2078)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5814)
[M::mem_pestat] mean and std.dev: (1204.36, 1309.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7682)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 293, 905)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2311)
[M::mem_pestat] mean and std.dev: (422.08, 336.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3014)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 709482 sequences (100000042 bp) in 3.056 CPU sec, 3.182 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 281977, 20, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (135, 207, 1249)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3477)
[M::mem_pestat] mean and std.dev: (381.07, 467.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4591)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 220, 319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 657)
[M::mem_pestat] mean and std.dev: (244.53, 121.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 826)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (245, 434, 1331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3503)
[M::mem_pestat] mean and std.dev: (589.72, 488.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4589)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 440, 1612)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4470)
[M::mem_pestat] mean and std.dev: (777.04, 839.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5899)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 708254 sequences (100000145 bp) in 2.220 CPU sec, 2.217 real sec...
[M::mem_process_seqs] Processed 699888 reads in 230.168 CPU sec, 7.335 real sec
[M::mem_process_seqs] Processed 706522 reads in 160.094 CPU sec, 5.099 real sec
sorting block 79, #reads = 1062806 mem = 536881532 peak = 1073364992
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 283287, 17, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 356, 1086)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2878)
[M::mem_pestat] mean and std.dev: (609.79, 634.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3774)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 213, 306)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 624)
[M::mem_pestat] mean and std.dev: (236.10, 115.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 783)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (491, 733, 1399)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3215)
[M::mem_pestat] mean and std.dev: (893.69, 711.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4123)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (272, 568, 974)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2378)
[M::mem_pestat] mean and std.dev: (666.25, 487.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3080)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 708462 sequences (100000264 bp) in 3.266 CPU sec, 3.381 real sec...
[M::process] read 706728 sequences (100000152 bp) in 2.698 CPU sec, 2.707 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 283024, 21, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 462, 1568)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4314)
[M::mem_pestat] mean and std.dev: (800.04, 795.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5687)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 216, 312)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 640)
[M::mem_pestat] mean and std.dev: (240.06, 118.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 804)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (495, 906, 1603)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3819)
[M::mem_pestat] mean and std.dev: (850.15, 524.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4927)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (249, 338, 640)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1422)
[M::mem_pestat] mean and std.dev: (363.83, 228.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1813)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 709482 reads in 262.160 CPU sec, 8.330 real sec
sorting block 80, #reads = 1061610 mem = 536880191 peak = 1073364992
[M::mem_process_seqs] Processed 708254 reads in 189.050 CPU sec, 6.038 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 283109, 15, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (291, 828, 2600)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7218)
[M::mem_pestat] mean and std.dev: (1372.46, 1585.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9527)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 216, 312)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 640)
[M::mem_pestat] mean and std.dev: (239.71, 117.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 804)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (592, 1177, 2366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5914)
[M::mem_pestat] mean and std.dev: (1954.80, 1804.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9171)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 315, 920)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2352)
[M::mem_pestat] mean and std.dev: (515.65, 486.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3068)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 81, #reads = 1062870 mem = 536885716 peak = 1073364992
[M::process] read 705942 sequences (100000181 bp) in 3.736 CPU sec, 3.956 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 282912, 27, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (315, 714, 1524)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3942)
[M::mem_pestat] mean and std.dev: (897.74, 1012.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5151)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 220, 318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 654)
[M::mem_pestat] mean and std.dev: (244.12, 120.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 822)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (578, 1022, 1939)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4661)
[M::mem_pestat] mean and std.dev: (1098.17, 747.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6022)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 294, 908)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2380)
[M::mem_pestat] mean and std.dev: (467.93, 500.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3116)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705280 sequences (100000256 bp) in 2.962 CPU sec, 2.968 real sec...
[M::mem_process_seqs] Processed 708462 reads in 281.368 CPU sec, 9.015 real sec
[M::mem_process_seqs] Processed 706728 reads in 188.973 CPU sec, 6.085 real sec
sorting block 82, #reads = 1060692 mem = 536883141 peak = 1073364992
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 282482, 26, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 260, 602)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1414)
[M::mem_pestat] mean and std.dev: (351.76, 267.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1820)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 221, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 661)
[M::mem_pestat] mean and std.dev: (246.03, 121.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 831)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (435, 824, 2235)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5835)
[M::mem_pestat] mean and std.dev: (1260.35, 1126.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7635)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 250, 606)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1432)
[M::mem_pestat] mean and std.dev: (394.10, 323.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1845)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704218 sequences (100000089 bp) in 3.752 CPU sec, 3.964 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 281896, 18, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (241, 641, 1580)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4258)
[M::mem_pestat] mean and std.dev: (842.11, 822.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5597)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 223, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 671)
[M::mem_pestat] mean and std.dev: (248.56, 123.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 844)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (534, 816, 1001)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1935)
[M::mem_pestat] mean and std.dev: (807.12, 376.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2402)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 297, 626)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1478)
[M::mem_pestat] mean and std.dev: (370.77, 309.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1904)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703500 sequences (100000094 bp) in 2.915 CPU sec, 2.923 real sec...
[M::mem_process_seqs] Processed 705942 reads in 266.064 CPU sec, 8.534 real sec
[M::mem_process_seqs] Processed 705280 reads in 179.345 CPU sec, 5.860 real sec
sorting block 83, #reads = 1062821 mem = 536879940 peak = 1073364992
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 281905, 19, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (250, 834, 1597)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4291)
[M::mem_pestat] mean and std.dev: (862.39, 783.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5638)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 227, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 679)
[M::mem_pestat] mean and std.dev: (251.38, 124.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 854)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (125, 577, 2984)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8702)
[M::mem_pestat] mean and std.dev: (1500.84, 1937.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11561)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 265, 709)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1793)
[M::mem_pestat] mean and std.dev: (390.64, 381.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2335)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702826 sequences (100000289 bp) in 4.369 CPU sec, 4.731 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 282222, 10, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 346, 617)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1511)
[M::mem_pestat] mean and std.dev: (413.57, 345.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1958)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 228, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 686)
[M::mem_pestat] mean and std.dev: (253.13, 125.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 863)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (267, 690, 1213)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3105)
[M::mem_pestat] mean and std.dev: (651.67, 420.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4051)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (250, 292, 1036)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2608)
[M::mem_pestat] mean and std.dev: (673.47, 714.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3533)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702756 sequences (100000025 bp) in 2.410 CPU sec, 2.408 real sec...
[M::mem_process_seqs] Processed 704218 reads in 253.057 CPU sec, 8.193 real sec
sorting block 84, #reads = 1063890 mem = 536883409 peak = 1073364992
[M::mem_process_seqs] Processed 703500 reads in 172.268 CPU sec, 5.558 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 281400, 29, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 311, 574)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1348)
[M::mem_pestat] mean and std.dev: (319.36, 222.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1735)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 230, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 690)
[M::mem_pestat] mean and std.dev: (255.03, 127.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 868)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (443, 1142, 1578)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3848)
[M::mem_pestat] mean and std.dev: (1068.30, 769.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4983)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 532, 1110)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2872)
[M::mem_pestat] mean and std.dev: (825.18, 889.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4382)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 85, #reads = 1065123 mem = 536880573 peak = 1073364992
[M::process] read 702754 sequences (100000263 bp) in 3.638 CPU sec, 3.796 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 281294, 12, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 380, 1069)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2831)
[M::mem_pestat] mean and std.dev: (571.89, 628.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3712)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 230, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 690)
[M::mem_pestat] mean and std.dev: (255.28, 127.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 868)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (267, 901, 1704)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4578)
[M::mem_pestat] mean and std.dev: (982.00, 862.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6015)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (233, 506, 1681)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4577)
[M::mem_pestat] mean and std.dev: (1003.61, 1118.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6025)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702826 reads in 234.136 CPU sec, 7.522 real sec
[M::process] read 702466 sequences (100000278 bp) in 3.017 CPU sec, 3.041 real sec...
[M::mem_process_seqs] Processed 702756 reads in 165.414 CPU sec, 5.496 real sec
sorting block 86, #reads = 1066415 mem = 536880017 peak = 1073364992
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 281378, 14, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 342, 1246)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3354)
[M::mem_pestat] mean and std.dev: (557.14, 662.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4408)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 229, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 692)
[M::mem_pestat] mean and std.dev: (255.00, 127.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 871)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (588, 1314, 3373)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8943)
[M::mem_pestat] mean and std.dev: (1749.29, 1288.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11728)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 348, 778)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1996)
[M::mem_pestat] mean and std.dev: (476.33, 482.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2605)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701352 sequences (100000297 bp) in 3.665 CPU sec, 3.847 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 281031, 23, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 496, 1493)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4063)
[M::mem_pestat] mean and std.dev: (794.95, 825.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5348)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 229, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 687)
[M::mem_pestat] mean and std.dev: (254.45, 126.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 864)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (931, 1538, 2365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5233)
[M::mem_pestat] mean and std.dev: (1505.05, 924.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6667)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 301, 895)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2273)
[M::mem_pestat] mean and std.dev: (444.05, 433.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2962)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701110 sequences (100000248 bp) in 1.990 CPU sec, 1.992 real sec...
[M::mem_process_seqs] Processed 702754 reads in 224.024 CPU sec, 7.396 real sec
[M::mem_process_seqs] Processed 702466 reads in 141.324 CPU sec, 4.531 real sec
sorting block 87, #reads = 1065924 mem = 536880247 peak = 1073364992
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 280459, 19, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 404, 1778)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4984)
[M::mem_pestat] mean and std.dev: (1009.80, 1147.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6587)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 233, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 698)
[M::mem_pestat] mean and std.dev: (258.15, 128.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 878)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (501, 877, 1036)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2106)
[M::mem_pestat] mean and std.dev: (797.28, 343.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2641)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 269, 498)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1094)
[M::mem_pestat] mean and std.dev: (308.61, 176.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1392)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700744 sequences (100000245 bp) in 2.819 CPU sec, 2.915 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 280260, 31, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 562, 1316)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3532)
[M::mem_pestat] mean and std.dev: (891.35, 806.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4640)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 234, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 704)
[M::mem_pestat] mean and std.dev: (259.35, 129.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 886)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (710, 972, 3075)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7805)
[M::mem_pestat] mean and std.dev: (1843.14, 2109.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10281)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 280, 992)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2518)
[M::mem_pestat] mean and std.dev: (448.17, 430.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3281)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700268 sequences (100000289 bp) in 2.220 CPU sec, 2.223 real sec...
[M::mem_process_seqs] Processed 701352 reads in 196.933 CPU sec, 6.313 real sec
sorting block 88, #reads = 1064933 mem = 536878571 peak = 1073364992
[M::mem_process_seqs] Processed 701110 reads in 135.242 CPU sec, 4.310 real sec
sorting block 89, #reads = 1063695 mem = 536878392 peak = 1073364992
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 279991, 25, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 376, 1534)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4200)
[M::mem_pestat] mean and std.dev: (954.91, 1057.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5533)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 234, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 707)
[M::mem_pestat] mean and std.dev: (259.79, 129.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 890)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (339, 892, 1812)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4758)
[M::mem_pestat] mean and std.dev: (1022.16, 740.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6231)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (231, 586, 1072)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2754)
[M::mem_pestat] mean and std.dev: (651.51, 527.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3595)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700634 sequences (100000152 bp) in 2.532 CPU sec, 2.632 real sec...
[M::process] read 700428 sequences (100000066 bp) in 2.080 CPU sec, 2.076 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 279892, 42, 69)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 477, 1419)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3853)
[M::mem_pestat] mean and std.dev: (754.88, 748.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5070)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 235, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 705)
[M::mem_pestat] mean and std.dev: (260.41, 129.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 887)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (545, 1276, 1387)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3071)
[M::mem_pestat] mean and std.dev: (1149.00, 808.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4385)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 711, 2245)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6297)
[M::mem_pestat] mean and std.dev: (1312.41, 1414.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8323)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700744 reads in 194.954 CPU sec, 6.227 real sec
[M::mem_process_seqs] Processed 700268 reads in 131.008 CPU sec, 4.238 real sec
sorting block 90, #reads = 1064657 mem = 536880137 peak = 1073364992
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 280139, 23, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 575, 1861)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5173)
[M::mem_pestat] mean and std.dev: (1040.70, 1044.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6829)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 234, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 701)
[M::mem_pestat] mean and std.dev: (259.22, 129.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 882)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (586, 1180, 2063)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5017)
[M::mem_pestat] mean and std.dev: (1468.39, 1255.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6494)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 367, 1000)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2554)
[M::mem_pestat] mean and std.dev: (453.05, 383.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3331)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701066 sequences (100000258 bp) in 2.973 CPU sec, 3.082 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 279860, 16, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 340, 754)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1848)
[M::mem_pestat] mean and std.dev: (416.19, 322.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2395)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 235, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 708)
[M::mem_pestat] mean and std.dev: (260.97, 131.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 891)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (404, 682, 1261)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2975)
[M::mem_pestat] mean and std.dev: (691.13, 463.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3832)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 358, 1445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3905)
[M::mem_pestat] mean and std.dev: (882.23, 852.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5135)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700722 sequences (100000191 bp) in 2.540 CPU sec, 2.547 real sec...
[M::mem_process_seqs] Processed 700634 reads in 193.126 CPU sec, 6.190 real sec
[M::mem_process_seqs] Processed 700428 reads in 141.321 CPU sec, 4.495 real sec
sorting block 91, #reads = 1065587 mem = 536881021 peak = 1073364992
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 279972, 19, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 303, 593)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1365)
[M::mem_pestat] mean and std.dev: (378.17, 288.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1751)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 234, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 701)
[M::mem_pestat] mean and std.dev: (259.43, 130.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 882)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (419, 868, 1676)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4190)
[M::mem_pestat] mean and std.dev: (911.39, 679.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5447)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 376, 584)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1370)
[M::mem_pestat] mean and std.dev: (419.83, 299.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1763)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700460 sequences (100000031 bp) in 3.152 CPU sec, 3.252 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 279890, 32, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 303, 1414)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3938)
[M::mem_pestat] mean and std.dev: (655.15, 882.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5200)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 234, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 704)
[M::mem_pestat] mean and std.dev: (259.76, 130.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 886)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (277, 880, 1989)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5413)
[M::mem_pestat] mean and std.dev: (1191.33, 1356.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7125)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 734, 1978)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5478)
[M::mem_pestat] mean and std.dev: (1073.58, 1106.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7228)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701066 reads in 204.822 CPU sec, 6.479 real sec
[M::process] read 704778 sequences (100000227 bp) in 2.800 CPU sec, 2.807 real sec...
sorting block 92, #reads = 1063964 mem = 536879560 peak = 1073364992
[M::mem_process_seqs] Processed 700722 reads in 146.327 CPU sec, 4.626 real sec
sorting block 93, #reads = 1062753 mem = 536886030 peak = 1073364992
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 279867, 23, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (233, 776, 1189)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3101)
[M::mem_pestat] mean and std.dev: (764.18, 578.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4057)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 235, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 711)
[M::mem_pestat] mean and std.dev: (261.79, 132.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 895)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (376, 1156, 2820)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7708)
[M::mem_pestat] mean and std.dev: (1650.26, 1553.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10152)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 385, 1125)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2953)
[M::mem_pestat] mean and std.dev: (559.10, 518.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3867)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 707280 sequences (100000099 bp) in 3.075 CPU sec, 3.182 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 280545, 23, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 287, 528)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1228)
[M::mem_pestat] mean and std.dev: (349.20, 239.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1578)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 224, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 671)
[M::mem_pestat] mean and std.dev: (248.75, 124.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 844)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 569, 1169)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3111)
[M::mem_pestat] mean and std.dev: (712.82, 661.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4082)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 263, 679)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1647)
[M::mem_pestat] mean and std.dev: (347.18, 282.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2131)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706998 sequences (100000224 bp) in 2.680 CPU sec, 2.676 real sec...
[M::mem_process_seqs] Processed 700460 reads in 228.871 CPU sec, 7.272 real sec
[M::mem_process_seqs] Processed 704778 reads in 169.353 CPU sec, 5.389 real sec
sorting block 94, #reads = 1057040 mem = 536882611 peak = 1073364992
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 282898, 20, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 500, 1236)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3308)
[M::mem_pestat] mean and std.dev: (649.43, 563.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4344)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 218, 316)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 650)
[M::mem_pestat] mean and std.dev: (242.54, 120.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 817)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (724, 1034, 1591)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3325)
[M::mem_pestat] mean and std.dev: (1161.30, 728.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4192)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 656, 1099)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2853)
[M::mem_pestat] mean and std.dev: (747.72, 644.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3730)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706210 sequences (100000293 bp) in 2.682 CPU sec, 2.798 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 283113, 22, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (264, 424, 1662)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4458)
[M::mem_pestat] mean and std.dev: (883.86, 978.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5856)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::process] read 704998 sequences (100000122 bp) in 2.040 CPU sec, 2.038 real sec...
[M::mem_pestat] (25, 50, 75) percentile: (150, 219, 317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 651)
[M::mem_pestat] mean and std.dev: (243.49, 120.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 818)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (244, 1164, 1720)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4672)
[M::mem_pestat] mean and std.dev: (1235.64, 1062.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6148)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 397, 1011)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2611)
[M::mem_pestat] mean and std.dev: (483.90, 371.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3411)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 707280 reads in 188.058 CPU sec, 5.982 real sec
[M::mem_process_seqs] Processed 706998 reads in 129.289 CPU sec, 4.192 real sec
sorting block 95, #reads = 1066323 mem = 536879996 peak = 1073364992
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 282762, 21, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (380, 955, 3079)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8477)
[M::mem_pestat] mean and std.dev: (1401.46, 1337.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11176)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 221, 320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 658)
[M::mem_pestat] mean and std.dev: (244.96, 121.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 827)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (126, 1005, 2701)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7851)
[M::mem_pestat] mean and std.dev: (1781.24, 2238.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10737)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 295, 657)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1577)
[M::mem_pestat] mean and std.dev: (459.61, 410.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2100)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704620 sequences (100000098 bp) in 2.847 CPU sec, 2.943 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 282286, 30, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 363, 1250)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3318)
[M::mem_pestat] mean and std.dev: (734.25, 804.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4352)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 224, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 671)
[M::mem_pestat] mean and std.dev: (248.95, 124.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 844)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (329, 1196, 2260)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6122)
[M::mem_pestat] mean and std.dev: (1347.34, 1108.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8053)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 221, 538)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1274)
[M::mem_pestat] mean and std.dev: (299.91, 220.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1642)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702998 sequences (100000101 bp) in 2.290 CPU sec, 2.292 real sec...
[M::mem_process_seqs] Processed 706210 reads in 193.803 CPU sec, 6.230 real sec
sorting block 96, #reads = 1068177 mem = 536882826 peak = 1073364992
[M::mem_process_seqs] Processed 704998 reads in 129.051 CPU sec, 4.090 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 282499, 39, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 400, 1772)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4970)
[M::mem_pestat] mean and std.dev: (776.56, 1018.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6569)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 224, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 669)
[M::mem_pestat] mean and std.dev: (248.94, 123.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 841)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (257, 646, 1349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3533)
[M::mem_pestat] mean and std.dev: (750.67, 772.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4625)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 355, 401)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 803)
[M::mem_pestat] mean and std.dev: (281.91, 134.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1004)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 97, #reads = 1071599 mem = 536879961 peak = 1089687552
[M::process] read 703190 sequences (100000276 bp) in 3.172 CPU sec, 3.251 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 281925, 22, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 262, 823)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2057)
[M::mem_pestat] mean and std.dev: (469.11, 451.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2674)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 229, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 686)
[M::mem_pestat] mean and std.dev: (253.58, 125.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 863)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 295, 822)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2112)
[M::mem_pestat] mean and std.dev: (382.89, 276.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2757)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 332, 1278)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3478)
[M::mem_pestat] mean and std.dev: (630.09, 701.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4578)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704620 reads in 178.134 CPU sec, 5.649 real sec
[M::mem_process_seqs] Processed 702998 reads in 125.251 CPU sec, 3.941 real sec
[M::process] read 702282 sequences (100000080 bp) in 2.793 CPU sec, 2.876 real sec...
sorting block 98, #reads = 1069675 mem = 536882174 peak = 1089687552
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 282030, 21, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 446, 1092)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2874)
[M::mem_pestat] mean and std.dev: (579.61, 504.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3765)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 228, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 680)
[M::mem_pestat] mean and std.dev: (252.63, 125.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 855)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (273, 872, 2694)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7536)
[M::mem_pestat] mean and std.dev: (1478.35, 1752.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9957)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (277, 643, 2110)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5776)
[M::mem_pestat] mean and std.dev: (1108.14, 1049.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7609)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702438 sequences (100000242 bp) in 3.225 CPU sec, 3.380 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 281888, 22, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 511, 1179)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3187)
[M::mem_pestat] mean and std.dev: (699.08, 597.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4191)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 231, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 690)
[M::mem_pestat] mean and std.dev: (255.69, 127.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 868)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (449, 711, 1367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3203)
[M::mem_pestat] mean and std.dev: (781.58, 664.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4121)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 252, 916)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2400)
[M::mem_pestat] mean and std.dev: (487.41, 511.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3142)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703190 reads in 181.179 CPU sec, 5.774 real sec
[M::mem_process_seqs] Processed 702282 reads in 128.238 CPU sec, 4.041 real sec
[M::process] read 702336 sequences (100000224 bp) in 3.060 CPU sec, 3.149 real sec...
sorting block 99, #reads = 1071423 mem = 536880278 peak = 1089687552
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 281517, 23, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 296, 1073)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2797)
[M::mem_pestat] mean and std.dev: (568.34, 577.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3659)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 231, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 693)
[M::mem_pestat] mean and std.dev: (255.44, 126.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 872)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (598, 1463, 1918)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4558)
[M::mem_pestat] mean and std.dev: (1406.00, 948.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5878)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 278, 1222)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3322)
[M::mem_pestat] mean and std.dev: (573.17, 618.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4372)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702202 sequences (100000190 bp) in 3.281 CPU sec, 3.416 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 281220, 25, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (233, 807, 2721)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7697)
[M::mem_pestat] mean and std.dev: (1205.29, 1241.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10185)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 231, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 687)
[M::mem_pestat] mean and std.dev: (254.97, 126.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 864)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 459, 2329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6603)
[M::mem_pestat] mean and std.dev: (962.39, 1099.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8740)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 303, 577)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1339)
[M::mem_pestat] mean and std.dev: (369.38, 191.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1720)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702438 reads in 190.751 CPU sec, 6.067 real sec
[M::mem_process_seqs] Processed 702336 reads in 136.748 CPU sec, 4.308 real sec
sorting block 100, #reads = 1070641 mem = 536884524 peak = 1089687552
[M::process] read 702394 sequences (100000264 bp) in 2.758 CPU sec, 2.854 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 281406, 31, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 242, 697)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1735)
[M::mem_pestat] mean and std.dev: (421.76, 404.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2254)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 232, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 693)
[M::mem_pestat] mean and std.dev: (255.92, 126.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 872)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (532, 865, 1438)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3250)
[M::mem_pestat] mean and std.dev: (930.00, 704.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4156)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 300, 890)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2228)
[M::mem_pestat] mean and std.dev: (530.11, 505.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2897)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 101, #reads = 1069066 mem = 536878899 peak = 1089687552
[M::process] read 702188 sequences (100000175 bp) in 3.403 CPU sec, 3.530 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 281880, 29, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 486, 990)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2582)
[M::mem_pestat] mean and std.dev: (566.72, 464.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3378)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 231, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 693)
[M::mem_pestat] mean and std.dev: (255.64, 127.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 872)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (247, 819, 2423)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6775)
[M::mem_pestat] mean and std.dev: (1180.69, 1069.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8951)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 407, 2947)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8461)
[M::mem_pestat] mean and std.dev: (1745.17, 2307.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11218)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702202 reads in 193.089 CPU sec, 6.122 real sec
[M::mem_process_seqs] Processed 702394 reads in 138.132 CPU sec, 4.343 real sec
[M::process] read 703192 sequences (100000291 bp) in 2.608 CPU sec, 2.707 real sec...
sorting block 102, #reads = 1069482 mem = 536884006 peak = 1089687552
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 281202, 19, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 332, 442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 884)
[M::mem_pestat] mean and std.dev: (300.59, 120.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1105)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 230, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 690)
[M::mem_pestat] mean and std.dev: (255.06, 126.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 868)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (305, 456, 1655)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4355)
[M::mem_pestat] mean and std.dev: (980.16, 1016.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5705)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 342, 955)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2427)
[M::mem_pestat] mean and std.dev: (587.14, 585.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3163)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703458 sequences (100000289 bp) in 2.823 CPU sec, 2.935 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 281769, 20, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 347, 825)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2143)
[M::mem_pestat] mean and std.dev: (436.02, 367.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2802)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 227, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 677)
[M::mem_pestat] mean and std.dev: (251.73, 124.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 851)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (334, 974, 2845)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7867)
[M::mem_pestat] mean and std.dev: (1347.37, 1423.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10378)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 609, 1430)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3838)
[M::mem_pestat] mean and std.dev: (832.35, 765.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5042)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703334 sequences (100000274 bp) in 1.900 CPU sec, 1.903 real sec...
[M::mem_process_seqs] Processed 702188 reads in 194.834 CPU sec, 6.196 real sec
[M::mem_process_seqs] Processed 703192 reads in 132.437 CPU sec, 4.290 real sec
sorting block 103, #reads = 1068313 mem = 536880624 peak = 1089687552
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 282036, 27, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 379, 1249)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3359)
[M::mem_pestat] mean and std.dev: (624.90, 674.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4414)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 227, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 676)
[M::mem_pestat] mean and std.dev: (251.33, 124.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 850)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (227, 485, 956)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2414)
[M::mem_pestat] mean and std.dev: (609.77, 468.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3143)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 262, 691)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1697)
[M::mem_pestat] mean and std.dev: (332.75, 208.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2200)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701832 sequences (100000102 bp) in 2.733 CPU sec, 2.878 real sec...
[M::process] read 701552 sequences (100000217 bp) in 2.020 CPU sec, 2.017 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 281410, 12, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 301, 1135)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2995)
[M::mem_pestat] mean and std.dev: (567.35, 622.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3925)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 228, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 686)
[M::mem_pestat] mean and std.dev: (253.59, 126.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 863)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (417, 2219, 7273)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 20985)
[M::mem_pestat] mean and std.dev: (3510.50, 3270.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 27841)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (376, 762, 1623)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4117)
[M::mem_pestat] mean and std.dev: (822.63, 635.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5364)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703458 reads in 203.911 CPU sec, 6.583 real sec
[M::mem_process_seqs] Processed 703334 reads in 138.025 CPU sec, 4.421 real sec
sorting block 104, #reads = 1068948 mem = 536878843 peak = 1089687552
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 281007, 25, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 244, 607)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1521)
[M::mem_pestat] mean and std.dev: (336.94, 301.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1978)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 232, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 696)
[M::mem_pestat] mean and std.dev: (256.82, 128.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 876)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (418, 1433, 2263)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5953)
[M::mem_pestat] mean and std.dev: (1509.76, 1155.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7798)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (265, 361, 1060)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2650)
[M::mem_pestat] mean and std.dev: (606.54, 574.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3445)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701272 sequences (100000096 bp) in 2.616 CPU sec, 2.715 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 280900, 35, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 376, 1076)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2858)
[M::mem_pestat] mean and std.dev: (526.25, 507.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3749)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 233, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 700)
[M::mem_pestat] mean and std.dev: (258.10, 128.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 881)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (279, 1022, 2792)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7818)
[M::mem_pestat] mean and std.dev: (1495.43, 1547.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10331)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 429, 940)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2402)
[M::mem_pestat] mean and std.dev: (572.89, 495.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3133)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701210 sequences (100000192 bp) in 2.660 CPU sec, 2.652 real sec...
[M::mem_process_seqs] Processed 701832 reads in 202.605 CPU sec, 6.472 real sec
sorting block 105, #reads = 1067047 mem = 536879872 peak = 1089687552
[M::mem_process_seqs] Processed 701552 reads in 136.214 CPU sec, 4.407 real sec
sorting block 106, #reads = 1066710 mem = 536882637 peak = 1206083584
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 280274, 27, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (250, 420, 929)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2287)
[M::mem_pestat] mean and std.dev: (548.67, 395.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2966)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 234, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 701)
[M::mem_pestat] mean and std.dev: (258.78, 129.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 882)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (508, 587, 931)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1777)
[M::mem_pestat] mean and std.dev: (606.21, 315.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2200)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (242, 421, 1220)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3176)
[M::mem_pestat] mean and std.dev: (667.31, 587.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4154)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701682 sequences (100000230 bp) in 3.197 CPU sec, 3.326 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 280436, 21, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 333, 496)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1050)
[M::mem_pestat] mean and std.dev: (300.52, 152.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1327)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 234, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 701)
[M::mem_pestat] mean and std.dev: (259.08, 129.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 882)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (397, 823, 1390)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3376)
[M::mem_pestat] mean and std.dev: (853.30, 627.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4369)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (242, 519, 1797)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4907)
[M::mem_pestat] mean and std.dev: (946.64, 1102.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6462)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702344 sequences (100000094 bp) in 2.330 CPU sec, 2.331 real sec...
[M::mem_process_seqs] Processed 701272 reads in 197.870 CPU sec, 6.345 real sec
[M::mem_process_seqs] Processed 701210 reads in 134.277 CPU sec, 4.237 real sec
sorting block 107, #reads = 1065453 mem = 536877365 peak = 1206083584
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 280791, 23, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (239, 821, 1711)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4655)
[M::mem_pestat] mean and std.dev: (959.98, 892.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6127)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 233, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 701)
[M::mem_pestat] mean and std.dev: (258.79, 129.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 882)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (288, 914, 1823)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4893)
[M::mem_pestat] mean and std.dev: (1254.78, 1255.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6428)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 351, 1681)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4653)
[M::mem_pestat] mean and std.dev: (841.00, 1104.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6139)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701984 sequences (100000045 bp) in 2.457 CPU sec, 2.535 real sec...
[M::process] read 710492 sequences (100000145 bp) in 1.860 CPU sec, 1.858 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 280631, 25, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 318, 955)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2491)
[M::mem_pestat] mean and std.dev: (533.98, 515.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3259)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 229, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 681)
[M::mem_pestat] mean and std.dev: (253.74, 126.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 856)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (459, 1159, 1397)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3273)
[M::mem_pestat] mean and std.dev: (1049.46, 838.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4404)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 715, 1643)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4547)
[M::mem_pestat] mean and std.dev: (917.25, 953.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5999)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701682 reads in 192.380 CPU sec, 6.119 real sec
sorting block 108, #reads = 1065062 mem = 536878412 peak = 1206083584
[M::mem_process_seqs] Processed 702344 reads in 131.583 CPU sec, 4.215 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 280440, 34, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 581, 2077)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5833)
[M::mem_pestat] mean and std.dev: (1208.45, 1569.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7711)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 231, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 694)
[M::mem_pestat] mean and std.dev: (256.53, 128.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 873)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (255, 419, 833)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1989)
[M::mem_pestat] mean and std.dev: (539.59, 444.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2567)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 353, 1282)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3512)
[M::mem_pestat] mean and std.dev: (585.60, 501.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4627)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 709956 sequences (100000152 bp) in 3.162 CPU sec, 3.242 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 283286, 11, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 408, 964)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2512)
[M::mem_pestat] mean and std.dev: (525.84, 489.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3286)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 211, 304)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 620)
[M::mem_pestat] mean and std.dev: (234.51, 115.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 778)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (551, 952, 1867)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4499)
[M::mem_pestat] mean and std.dev: (1505.64, 1468.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7381)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 352, 1123)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2955)
[M::mem_pestat] mean and std.dev: (555.19, 486.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3871)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 710842 sequences (100000009 bp) in 2.720 CPU sec, 2.721 real sec...
[M::mem_process_seqs] Processed 701984 reads in 226.980 CPU sec, 7.209 real sec
sorting block 109, #reads = 1063624 mem = 536881865 peak = 1206083584
[M::mem_process_seqs] Processed 710492 reads in 156.161 CPU sec, 4.943 real sec
sorting block 110, #reads = 1054536 mem = 536881645 peak = 1206083584
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 284280, 20, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 701, 1263)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3327)
[M::mem_pestat] mean and std.dev: (718.56, 562.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4359)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 212, 307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 629)
[M::mem_pestat] mean and std.dev: (236.17, 116.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 790)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (256, 560, 1505)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4003)
[M::mem_pestat] mean and std.dev: (655.61, 535.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5252)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 423, 1319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3515)
[M::mem_pestat] mean and std.dev: (936.17, 1025.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5037)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 708974 sequences (100000118 bp) in 3.125 CPU sec, 3.218 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 284255, 20, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 313, 690)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1726)
[M::mem_pestat] mean and std.dev: (398.74, 306.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2244)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 211, 304)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 622)
[M::mem_pestat] mean and std.dev: (234.18, 114.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 781)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1003, 1290, 3650)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8944)
[M::mem_pestat] mean and std.dev: (2228.50, 1909.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11591)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (255, 632, 1567)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4191)
[M::mem_pestat] mean and std.dev: (1111.92, 1089.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5503)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 709496 sequences (100000000 bp) in 2.720 CPU sec, 2.719 real sec...
[M::mem_process_seqs] Processed 709956 reads in 213.160 CPU sec, 6.744 real sec
[M::mem_process_seqs] Processed 710842 reads in 152.541 CPU sec, 4.819 real sec
sorting block 111, #reads = 1066834 mem = 536881865 peak = 1206083584
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 283583, 17, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 260, 1502)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4170)
[M::mem_pestat] mean and std.dev: (742.00, 804.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5504)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 215, 309)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 633)
[M::mem_pestat] mean and std.dev: (237.87, 116.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 795)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 271, 1794)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5060)
[M::mem_pestat] mean and std.dev: (664.44, 757.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6693)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 429, 699)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1647)
[M::mem_pestat] mean and std.dev: (535.32, 408.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2167)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 707592 sequences (100000288 bp) in 3.303 CPU sec, 3.389 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 283474, 21, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 289, 855)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2189)
[M::mem_pestat] mean and std.dev: (417.90, 398.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2856)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 214, 309)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 633)
[M::mem_pestat] mean and std.dev: (237.72, 117.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 795)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (407, 843, 1488)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3650)
[M::mem_pestat] mean and std.dev: (939.81, 655.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4731)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 285, 946)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2406)
[M::mem_pestat] mean and std.dev: (459.81, 453.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3136)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706454 sequences (100000123 bp) in 2.580 CPU sec, 2.578 real sec...
[M::mem_process_seqs] Processed 708974 reads in 218.778 CPU sec, 7.266 real sec
sorting block 112, #reads = 1064316 mem = 536879276 peak = 1206083584
[M::mem_process_seqs] Processed 709496 reads in 148.858 CPU sec, 4.768 real sec
sorting block 113, #reads = 1062708 mem = 536890631 peak = 1206083584
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 283092, 29, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 333, 1489)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4083)
[M::mem_pestat] mean and std.dev: (878.76, 987.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5380)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 218, 315)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 647)
[M::mem_pestat] mean and std.dev: (241.69, 118.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 813)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (480, 1295, 2084)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5292)
[M::mem_pestat] mean and std.dev: (1378.52, 1084.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6896)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 217, 1030)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2768)
[M::mem_pestat] mean and std.dev: (557.24, 714.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3637)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704934 sequences (100000212 bp) in 3.176 CPU sec, 3.243 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 282638, 12, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 329, 604)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1404)
[M::mem_pestat] mean and std.dev: (329.76, 188.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1804)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 221, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 663)
[M::mem_pestat] mean and std.dev: (245.69, 121.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 834)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (233, 826, 1752)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4790)
[M::mem_pestat] mean and std.dev: (1099.67, 1083.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6309)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 309, 783)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1911)
[M::mem_pestat] mean and std.dev: (451.46, 373.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2475)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704582 sequences (100000137 bp) in 2.600 CPU sec, 2.600 real sec...
[M::mem_process_seqs] Processed 707592 reads in 208.939 CPU sec, 6.657 real sec
[M::mem_process_seqs] Processed 706454 reads in 141.353 CPU sec, 4.533 real sec
sorting block 114, #reads = 1063377 mem = 536878559 peak = 1206083584
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 282567, 20, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (240, 302, 907)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2241)
[M::mem_pestat] mean and std.dev: (450.69, 457.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2908)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 225, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 674)
[M::mem_pestat] mean and std.dev: (249.55, 124.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 848)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (317, 594, 1628)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4250)
[M::mem_pestat] mean and std.dev: (748.94, 880.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5561)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 231, 776)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2068)
[M::mem_pestat] mean and std.dev: (502.86, 574.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2801)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704694 sequences (100000024 bp) in 3.126 CPU sec, 3.213 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 282630, 17, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 684, 1300)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3568)
[M::mem_pestat] mean and std.dev: (641.33, 552.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4702)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 224, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 672)
[M::mem_pestat] mean and std.dev: (249.57, 124.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 845)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (244, 504, 931)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2305)
[M::mem_pestat] mean and std.dev: (555.47, 482.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2992)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 293, 1141)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2991)
[M::mem_pestat] mean and std.dev: (614.31, 674.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3916)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704934 reads in 192.978 CPU sec, 6.178 real sec
[M::process] read 704126 sequences (100000104 bp) in 2.684 CPU sec, 2.694 real sec...
[M::mem_process_seqs] Processed 704582 reads in 134.145 CPU sec, 4.271 real sec
sorting block 115, #reads = 1065994 mem = 536878614 peak = 1206083584
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 282566, 25, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 468, 1192)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3140)
[M::mem_pestat] mean and std.dev: (626.03, 543.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4114)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 225, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 681)
[M::mem_pestat] mean and std.dev: (251.02, 125.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 857)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (417, 1630, 2925)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7941)
[M::mem_pestat] mean and std.dev: (1652.96, 1277.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10449)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 314, 587)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1409)
[M::mem_pestat] mean and std.dev: (351.88, 307.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1820)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704088 sequences (100000230 bp) in 3.251 CPU sec, 3.345 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 282220, 33, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 500, 1165)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3063)
[M::mem_pestat] mean and std.dev: (686.77, 691.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4012)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 227, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 682)
[M::mem_pestat] mean and std.dev: (252.08, 125.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 858)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (130, 641, 1189)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3307)
[M::mem_pestat] mean and std.dev: (796.82, 769.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4366)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (245, 394, 774)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1832)
[M::mem_pestat] mean and std.dev: (475.61, 407.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2361)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704694 reads in 192.962 CPU sec, 6.139 real sec
[M::process] read 703656 sequences (100000225 bp) in 2.715 CPU sec, 2.739 real sec...
[M::mem_process_seqs] Processed 704126 reads in 134.183 CPU sec, 4.351 real sec
sorting block 116, #reads = 1067660 mem = 536886897 peak = 1206083584
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 281632, 32, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 365, 971)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2523)
[M::mem_pestat] mean and std.dev: (599.87, 537.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3299)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 226, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 679)
[M::mem_pestat] mean and std.dev: (251.95, 126.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 854)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (124, 868, 1311)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3685)
[M::mem_pestat] mean and std.dev: (678.36, 634.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4872)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 299, 799)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2061)
[M::mem_pestat] mean and std.dev: (417.18, 329.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2692)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 117, #reads = 1069203 mem = 536878076 peak = 1206083584
[M::process] read 703478 sequences (100000017 bp) in 3.115 CPU sec, 3.225 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 281580, 28, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 317, 1134)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2982)
[M::mem_pestat] mean and std.dev: (590.70, 563.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3906)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 227, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 688)
[M::mem_pestat] mean and std.dev: (253.47, 127.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 866)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (347, 578, 1403)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3515)
[M::mem_pestat] mean and std.dev: (748.96, 545.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4571)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 558, 1154)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3040)
[M::mem_pestat] mean and std.dev: (733.00, 627.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3983)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704088 reads in 193.815 CPU sec, 6.267 real sec
[M::process] read 702300 sequences (100000083 bp) in 2.805 CPU sec, 2.834 real sec...
[M::mem_process_seqs] Processed 703656 reads in 137.326 CPU sec, 4.529 real sec
sorting block 118, #reads = 1066846 mem = 536883832 peak = 1206083584
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 281318, 30, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 331, 643)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1611)
[M::mem_pestat] mean and std.dev: (356.68, 317.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2095)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 228, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 691)
[M::mem_pestat] mean and std.dev: (254.32, 127.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 870)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 539, 694)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1682)
[M::mem_pestat] mean and std.dev: (402.29, 272.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2176)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 407, 741)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1795)
[M::mem_pestat] mean and std.dev: (481.20, 358.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2322)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702482 sequences (100000018 bp) in 3.214 CPU sec, 3.353 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 281691, 19, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (232, 311, 823)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2005)
[M::mem_pestat] mean and std.dev: (437.50, 373.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2596)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 231, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 693)
[M::mem_pestat] mean and std.dev: (256.19, 127.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 872)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (554, 1048, 3473)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9311)
[M::mem_pestat] mean and std.dev: (2168.58, 2185.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12230)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 458, 1590)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4314)
[M::mem_pestat] mean and std.dev: (934.87, 1058.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5676)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703478 reads in 198.759 CPU sec, 6.501 real sec
[M::process] read 701888 sequences (100000099 bp) in 2.688 CPU sec, 2.708 real sec...
[M::mem_process_seqs] Processed 702300 reads in 141.437 CPU sec, 4.532 real sec
sorting block 119, #reads = 1067935 mem = 536879107 peak = 1206083584
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 281113, 24, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 274, 1742)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4842)
[M::mem_pestat] mean and std.dev: (751.18, 852.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6392)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 232, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 699)
[M::mem_pestat] mean and std.dev: (257.36, 128.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 880)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (558, 1054, 1470)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3294)
[M::mem_pestat] mean and std.dev: (942.15, 594.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4206)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (283, 427, 2217)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6085)
[M::mem_pestat] mean and std.dev: (1035.03, 961.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8019)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701142 sequences (100000085 bp) in 3.421 CPU sec, 3.571 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 280845, 29, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 311, 775)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2005)
[M::mem_pestat] mean and std.dev: (364.33, 332.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2620)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 232, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 697)
[M::mem_pestat] mean and std.dev: (257.31, 128.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 877)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 532, 1138)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3034)
[M::mem_pestat] mean and std.dev: (694.64, 666.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3982)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (279, 598, 1044)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2574)
[M::mem_pestat] mean and std.dev: (705.36, 573.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3339)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702482 reads in 197.451 CPU sec, 6.325 real sec
[M::mem_process_seqs] Processed 701888 reads in 138.834 CPU sec, 4.372 real sec
[M::process] read 701074 sequences (100000285 bp) in 3.000 CPU sec, 3.070 real sec...
sorting block 120, #reads = 1067042 mem = 536879000 peak = 1206083584
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 280470, 26, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 351, 1389)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3761)
[M::mem_pestat] mean and std.dev: (679.84, 782.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4947)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 236, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 713)
[M::mem_pestat] mean and std.dev: (260.78, 130.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 898)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (227, 460, 1497)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4037)
[M::mem_pestat] mean and std.dev: (835.12, 914.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5307)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (267, 437, 1028)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2550)
[M::mem_pestat] mean and std.dev: (626.41, 489.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3311)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701090 sequences (100000152 bp) in 3.363 CPU sec, 3.509 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 280372, 14, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 363, 956)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2520)
[M::mem_pestat] mean and std.dev: (595.02, 567.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3302)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 237, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 714)
[M::mem_pestat] mean and std.dev: (261.63, 130.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 899)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (338, 614, 874)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1946)
[M::mem_pestat] mean and std.dev: (677.69, 488.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2631)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (253, 449, 1003)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2503)
[M::mem_pestat] mean and std.dev: (459.70, 335.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3253)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701142 reads in 202.934 CPU sec, 6.441 real sec
sorting block 121, #reads = 1067168 mem = 536884802 peak = 1206083584
[M::process] read 700052 sequences (100000253 bp) in 2.733 CPU sec, 2.755 real sec...
[M::mem_process_seqs] Processed 701074 reads in 143.966 CPU sec, 4.555 real sec
sorting block 122, #reads = 1066565 mem = 536880803 peak = 1206083584
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 280962, 25, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 358, 1345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3625)
[M::mem_pestat] mean and std.dev: (604.75, 567.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4765)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 235, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 707)
[M::mem_pestat] mean and std.dev: (260.17, 129.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 890)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (243, 412, 2344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6546)
[M::mem_pestat] mean and std.dev: (713.05, 831.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8647)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 463, 698)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1658)
[M::mem_pestat] mean and std.dev: (437.76, 255.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2138)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699710 sequences (100000245 bp) in 2.658 CPU sec, 2.767 real sec...
[M::process] read 201780 sequences (28731182 bp) in 0.820 CPU sec, 0.819 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 280432, 16, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 459, 1712)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4674)
[M::mem_pestat] mean and std.dev: (819.03, 722.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6155)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 238, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 709)
[M::mem_pestat] mean and std.dev: (261.49, 129.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 892)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (485, 1199, 1492)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3506)
[M::mem_pestat] mean and std.dev: (994.06, 582.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4513)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 590, 1437)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3867)
[M::mem_pestat] mean and std.dev: (934.15, 946.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5082)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701090 reads in 200.481 CPU sec, 6.433 real sec
[M::mem_process_seqs] Processed 700052 reads in 143.346 CPU sec, 4.609 real sec
sorting block 123, #reads = 1067062 mem = 536879203 peak = 1206083584
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (7, 80991, 11, 8)
[M::mem_pestat] skip orientation FF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 232, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 699)
[M::mem_pestat] mean and std.dev: (256.36, 127.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 880)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (635, 635, 2847)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7271)
[M::mem_pestat] mean and std.dev: (1474.45, 1120.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9483)
[M::mem_pestat] skip orientation RR as there are not enough pairs
[M::mem_pestat] skip orientation RF
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 280102, 20, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 295, 767)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1977)
[M::mem_pestat] mean and std.dev: (400.11, 425.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2582)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 238, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 710)
[M::mem_pestat] mean and std.dev: (262.35, 129.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 893)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (847, 2551, 4150)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10756)
[M::mem_pestat] mean and std.dev: (2937.35, 2421.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14059)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (261, 393, 955)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2343)
[M::mem_pestat] mean and std.dev: (509.59, 359.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3037)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 201780 reads in 110.807 CPU sec, 3.586 real sec
[M::mem_process_seqs] Processed 699710 reads in 135.850 CPU sec, 4.405 real sec
sorting block 124, #reads = 1066549 mem = 536882732 peak = 1224380416
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000c06f2
  features: bfebfbff 7ffefbff
  extended: f3bfb7ef fb417ffe
  amd bits: 2c100800 00000121
     brand: INTEL(R) XEON(R) PLATINUM 8559C
threads: 31
algo: bwa-mem
license: sentieon:klib=31
reads: 132866564
overall: 70146408448 mem 25975.389 user 822.321 sys 885.181 real
[main] Version: 0.7.17-r1188
[main] CMD: /opt/conda/share/sentieon-202308.03-3/libexec/bwa mem -K 100000000 -Y -R @RG\tID:A23MHWWLT4.1136_76X-T1-TDNA-1_A23MHWWLT4_1.L006\tPU:L006\tSM:1136_76X-T1-TDNA-1_A23MHWWLT4_1\tLB:1136_76X-T1-TDNA-1_A23MHWWLT4_1\tDS:s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta\tPL:ILLUMINA -t 31 ./BWAIndex/Homo_sapiens_assembly38.fasta.64 1136_76X-T1-TDNA-1_A23MHWWLT4_1_R1.fastq.gz 1136_76X-T1-TDNA-1_A23MHWWLT4_1_R2.fastq.gz
[main] Real time: 885.234 sec; CPU: 26797.727 sec
sorting block 125, #reads = 530869 mem = 267560631 peak = 1224380416
uniq header count 1
merging 126 blocks
sw version: sentieon-genomics-202308.03
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000c06f2
  features: bfebfbff 7ffefbff
  extended: f3bfb7ef fb417ffe
  amd bits: 2c100800 00000121
     brand: INTEL(R) XEON(R) PLATINUM 8559C
threads: 31 max 192
algo: util-sort
license: sentieon:util=1
output file size: 7837512275
output reads: 133969084
bam_mem_sort: 126 calls 74.370 user 0.931 sys 75.466 real
bam_write: 126 calls 53.757 user 3.707 sys 62.768 real
execute: 1 calls 33.075 user 1.542 sys 935.361 real
merge_files: 1 calls 33.042 user 1.506 sys 49.600 real
parse_chunk: 2008 calls 116.247 user 29.338 sys 149.054 real
read_chunk: 5439 calls 64.563 user 43.856 sys 816.137 real
sort_block: 1 calls 48.107 user 43.327 sys 793.262 real
write_chunk: 3429 calls 32.644 user 1.222 sys 48.559 real
overall: 3522416640 mem 2027.880 user 100.226 sys 935.385 real
ls: cannot access '*.cram': No such file or directory