cmdline: /opt/conda/share/sentieon-202308.03-3/libexec/util sort -r Homo_sapiens_assembly38.fasta -t 31 -o 1136_85O-T1-TDNA-1_A23MHWWLT4_1.bam --sam2bam -
This software is licensed to bgold@natera.com by Sentieon Inc.
This software is licensed to bgold@natera.com by Sentieon Inc.
version: sentieon-genomics-202308.03
[M::bwa_idx_load_from_disk] read 3171 ALT contigs
[M::main_mem] bwa index loaded in 1844.690 CPU sec, 69.278 real sec
[M::process] read 706200 sequences (100000115 bp) in 1.695 CPU sec, 1.701 real sec...
[M::process] read 705252 sequences (100000276 bp) in 1.900 CPU sec, 1.917 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (101, 284978, 40, 90)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 360, 724)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1790)
[M::mem_pestat] mean and std.dev: (356.02, 236.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2323)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 232, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 720)
[M::mem_pestat] mean and std.dev: (258.55, 133.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 909)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (359, 930, 2117)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5633)
[M::mem_pestat] mean and std.dev: (1251.51, 1212.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7391)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 363, 842)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2112)
[M::mem_pestat] mean and std.dev: (460.94, 378.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2747)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704454 sequences (100000078 bp) in 1.823 CPU sec, 1.853 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (126, 284809, 45, 85)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 297, 504)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1152)
[M::mem_pestat] mean and std.dev: (303.76, 196.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1476)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 234, 345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 727)
[M::mem_pestat] mean and std.dev: (260.88, 135.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 918)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (447, 1206, 2151)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5559)
[M::mem_pestat] mean and std.dev: (1220.19, 1038.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7263)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 308, 1592)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4406)
[M::mem_pestat] mean and std.dev: (728.16, 948.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5813)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703642 sequences (100000072 bp) in 1.781 CPU sec, 1.799 real sec...
[M::mem_process_seqs] Processed 706200 reads in 185.712 CPU sec, 5.871 real sec
[M::mem_process_seqs] Processed 705252 reads in 128.371 CPU sec, 4.081 real sec
sorting block 0, #reads = 1079173 mem = 536883427 peak = 590249984
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (91, 284686, 62, 102)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 289, 663)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1637)
[M::mem_pestat] mean and std.dev: (381.14, 330.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2124)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 236, 349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 737)
[M::mem_pestat] mean and std.dev: (263.01, 136.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 931)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 998, 3127)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8973)
[M::mem_pestat] mean and std.dev: (1720.26, 1967.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11896)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 335, 572)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1328)
[M::mem_pestat] mean and std.dev: (359.93, 253.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1706)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702116 sequences (100000037 bp) in 2.731 CPU sec, 2.939 real sec...
[M::process] read 701744 sequences (100000196 bp) in 1.949 CPU sec, 1.958 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (105, 284028, 37, 92)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 274, 515)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1175)
[M::mem_pestat] mean and std.dev: (321.60, 195.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1505)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 238, 352)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 744)
[M::mem_pestat] mean and std.dev: (265.61, 137.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 940)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (275, 735, 1890)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5120)
[M::mem_pestat] mean and std.dev: (1126.00, 1056.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6735)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 267, 575)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1385)
[M::mem_pestat] mean and std.dev: (346.00, 291.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1790)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704454 reads in 186.108 CPU sec, 5.897 real sec
[M::mem_process_seqs] Processed 703642 reads in 210.213 CPU sec, 6.685 real sec
sorting block 1, #reads = 1078728 mem = 536880600 peak = 747536384
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (124, 283699, 46, 101)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 330, 907)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2369)
[M::mem_pestat] mean and std.dev: (471.35, 491.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3100)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 244, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 763)
[M::mem_pestat] mean and std.dev: (271.83, 141.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 964)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (511, 1237, 2030)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5068)
[M::mem_pestat] mean and std.dev: (1241.62, 1072.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6587)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 292, 643)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1515)
[M::mem_pestat] mean and std.dev: (389.99, 311.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1951)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700820 sequences (100000061 bp) in 2.830 CPU sec, 2.992 real sec...
[M::process] read 700952 sequences (100000175 bp) in 1.950 CPU sec, 1.957 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (100, 283967, 43, 91)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 307, 483)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1049)
[M::mem_pestat] mean and std.dev: (304.60, 173.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1332)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 242, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 756)
[M::mem_pestat] mean and std.dev: (269.32, 139.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 955)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (326, 908, 3760)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10628)
[M::mem_pestat] mean and std.dev: (1976.63, 1979.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14062)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 329, 980)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2490)
[M::mem_pestat] mean and std.dev: (452.83, 446.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3245)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701744 reads in 186.978 CPU sec, 5.922 real sec
sorting block 2, #reads = 1077262 mem = 536879597 peak = 796323840
[M::mem_process_seqs] Processed 702116 reads in 210.705 CPU sec, 6.700 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (104, 283375, 45, 109)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 340, 1407)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3833)
[M::mem_pestat] mean and std.dev: (773.21, 894.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5046)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 245, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 773)
[M::mem_pestat] mean and std.dev: (273.93, 142.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 977)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (365, 683, 2971)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8183)
[M::mem_pestat] mean and std.dev: (1550.95, 1785.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10789)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 293, 552)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1284)
[M::mem_pestat] mean and std.dev: (305.51, 190.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1650)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700540 sequences (100000181 bp) in 3.429 CPU sec, 3.655 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (115, 283733, 53, 143)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 316, 626)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1504)
[M::mem_pestat] mean and std.dev: (399.90, 318.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1943)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 246, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 773)
[M::mem_pestat] mean and std.dev: (274.52, 143.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 977)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (283, 618, 1157)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2905)
[M::mem_pestat] mean and std.dev: (847.56, 785.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3988)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (235, 402, 651)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1483)
[M::mem_pestat] mean and std.dev: (415.56, 276.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1899)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700526 sequences (100000079 bp) in 2.165 CPU sec, 2.169 real sec...
[M::mem_process_seqs] Processed 700820 reads in 189.529 CPU sec, 5.992 real sec
sorting block 3, #reads = 1078529 mem = 536879108 peak = 796323840
[M::mem_process_seqs] Processed 700952 reads in 131.799 CPU sec, 4.186 real sec
sorting block 4, #reads = 1076486 mem = 536879156 peak = 890232832
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (103, 283868, 42, 136)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 263, 661)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1645)
[M::mem_pestat] mean and std.dev: (337.52, 282.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2137)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 246, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 770)
[M::mem_pestat] mean and std.dev: (273.87, 142.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 973)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (544, 1202, 2214)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5554)
[M::mem_pestat] mean and std.dev: (1519.39, 1394.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7224)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 351, 863)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2149)
[M::mem_pestat] mean and std.dev: (490.22, 441.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2792)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700142 sequences (100000157 bp) in 3.031 CPU sec, 3.251 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (103, 283431, 54, 141)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 257, 469)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1041)
[M::mem_pestat] mean and std.dev: (295.79, 192.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1327)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 245, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 764)
[M::mem_pestat] mean and std.dev: (272.70, 140.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 965)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (513, 1136, 1942)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4800)
[M::mem_pestat] mean and std.dev: (983.73, 750.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6229)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (248, 409, 819)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1961)
[M::mem_pestat] mean and std.dev: (526.68, 430.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2532)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700434 sequences (100000266 bp) in 2.077 CPU sec, 2.081 real sec...
[M::mem_process_seqs] Processed 700540 reads in 196.262 CPU sec, 6.226 real sec
[M::mem_process_seqs] Processed 700526 reads in 135.428 CPU sec, 4.287 real sec
sorting block 5, #reads = 1076972 mem = 536879114 peak = 890232832
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (84, 283570, 53, 131)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (228, 409, 1770)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4854)
[M::mem_pestat] mean and std.dev: (1003.84, 1105.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6396)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 245, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 758)
[M::mem_pestat] mean and std.dev: (271.64, 139.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 957)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (361, 1207, 3381)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9421)
[M::mem_pestat] mean and std.dev: (2005.19, 2040.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12441)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 335, 651)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1581)
[M::mem_pestat] mean and std.dev: (358.67, 261.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2046)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700290 sequences (100000145 bp) in 3.560 CPU sec, 3.713 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (88, 283539, 52, 102)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 273, 548)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1262)
[M::mem_pestat] mean and std.dev: (349.14, 247.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1619)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 244, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 758)
[M::mem_pestat] mean and std.dev: (271.52, 140.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 957)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 548, 1740)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4836)
[M::mem_pestat] mean and std.dev: (769.26, 992.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6384)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 313, 500)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1088)
[M::mem_pestat] mean and std.dev: (315.06, 166.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1382)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700142 reads in 199.815 CPU sec, 6.329 real sec
[M::process] read 699916 sequences (100000158 bp) in 2.827 CPU sec, 2.864 real sec...
[M::mem_process_seqs] Processed 700434 reads in 135.441 CPU sec, 4.268 real sec
sorting block 6, #reads = 1076887 mem = 536879122 peak = 890232832
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (89, 283274, 39, 111)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 314, 562)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1288)
[M::mem_pestat] mean and std.dev: (333.26, 209.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1651)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 244, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 758)
[M::mem_pestat] mean and std.dev: (271.88, 140.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 957)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (256, 1158, 2417)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6739)
[M::mem_pestat] mean and std.dev: (1443.08, 1382.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8900)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (245, 383, 642)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1436)
[M::mem_pestat] mean and std.dev: (408.42, 266.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1833)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699702 sequences (100000150 bp) in 2.976 CPU sec, 3.089 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (108, 283281, 50, 144)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 339, 623)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1497)
[M::mem_pestat] mean and std.dev: (409.43, 341.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1934)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 247, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 765)
[M::mem_pestat] mean and std.dev: (273.67, 141.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 966)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (706, 1589, 2701)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6691)
[M::mem_pestat] mean and std.dev: (1935.74, 1610.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8686)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 330, 667)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1613)
[M::mem_pestat] mean and std.dev: (382.43, 297.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2086)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699098 sequences (100000160 bp) in 2.390 CPU sec, 2.385 real sec...
[M::mem_process_seqs] Processed 700290 reads in 200.019 CPU sec, 6.365 real sec
sorting block 7, #reads = 1077307 mem = 536879467 peak = 890232832
[M::mem_process_seqs] Processed 699916 reads in 134.883 CPU sec, 4.276 real sec
sorting block 8, #reads = 1077500 mem = 536876917 peak = 890232832
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (101, 283180, 57, 138)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 271, 500)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1198)
[M::mem_pestat] mean and std.dev: (295.96, 230.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1547)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 247, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 765)
[M::mem_pestat] mean and std.dev: (273.60, 140.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 966)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (238, 612, 2239)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6241)
[M::mem_pestat] mean and std.dev: (1226.61, 1415.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8242)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 342, 920)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2370)
[M::mem_pestat] mean and std.dev: (532.46, 505.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3095)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698862 sequences (100000222 bp) in 3.408 CPU sec, 3.568 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (112, 282775, 41, 88)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (237, 414, 1045)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2661)
[M::mem_pestat] mean and std.dev: (569.90, 565.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3469)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 249, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 769)
[M::mem_pestat] mean and std.dev: (275.11, 140.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 971)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (339, 727, 2496)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6810)
[M::mem_pestat] mean and std.dev: (1509.68, 1474.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8967)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 291, 624)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1476)
[M::mem_pestat] mean and std.dev: (322.73, 265.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1902)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698406 sequences (100000285 bp) in 2.280 CPU sec, 2.280 real sec...
[M::mem_process_seqs] Processed 699702 reads in 196.186 CPU sec, 6.213 real sec
[M::mem_process_seqs] Processed 699098 reads in 135.370 CPU sec, 4.275 real sec
sorting block 9, #reads = 1076380 mem = 536876260 peak = 890232832
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (124, 283294, 60, 126)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 275, 562)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1320)
[M::mem_pestat] mean and std.dev: (295.33, 196.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1699)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 250, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 770)
[M::mem_pestat] mean and std.dev: (275.91, 140.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 972)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (788, 1066, 2271)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5237)
[M::mem_pestat] mean and std.dev: (1399.86, 1059.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6720)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 343, 594)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1346)
[M::mem_pestat] mean and std.dev: (377.28, 241.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1722)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698480 sequences (100000028 bp) in 2.968 CPU sec, 3.122 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (109, 282721, 40, 77)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 288, 732)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1864)
[M::mem_pestat] mean and std.dev: (440.73, 408.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2430)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 252, 369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 777)
[M::mem_pestat] mean and std.dev: (278.07, 142.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 981)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (256, 339, 2221)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6151)
[M::mem_pestat] mean and std.dev: (1306.08, 1764.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8365)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 285, 559)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1289)
[M::mem_pestat] mean and std.dev: (296.40, 167.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1654)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697796 sequences (100000059 bp) in 2.280 CPU sec, 2.287 real sec...
[M::mem_process_seqs] Processed 698862 reads in 192.905 CPU sec, 6.121 real sec
[M::mem_process_seqs] Processed 698406 reads in 132.899 CPU sec, 4.208 real sec
sorting block 10, #reads = 1078141 mem = 536879368 peak = 890232832
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (124, 282787, 45, 135)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 282, 840)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2158)
[M::mem_pestat] mean and std.dev: (364.17, 328.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2817)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 252, 370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 780)
[M::mem_pestat] mean and std.dev: (278.47, 143.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 985)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (348, 900, 2166)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5802)
[M::mem_pestat] mean and std.dev: (1480.80, 1530.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7620)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 265, 608)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1450)
[M::mem_pestat] mean and std.dev: (369.87, 284.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1871)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704714 sequences (100000247 bp) in 3.320 CPU sec, 3.503 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (104, 282501, 41, 98)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 237, 416)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 950)
[M::mem_pestat] mean and std.dev: (263.63, 183.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1217)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 255, 374)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 790)
[M::mem_pestat] mean and std.dev: (281.19, 144.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 998)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (408, 743, 2594)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6966)
[M::mem_pestat] mean and std.dev: (1431.53, 1397.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9152)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 312, 504)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1122)
[M::mem_pestat] mean and std.dev: (325.44, 177.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1431)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698480 reads in 193.549 CPU sec, 6.141 real sec
[M::process] read 705524 sequences (100000035 bp) in 2.298 CPU sec, 2.304 real sec...
sorting block 11, #reads = 1075933 mem = 536878737 peak = 890232832
[M::mem_process_seqs] Processed 697796 reads in 133.209 CPU sec, 4.225 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (89, 284887, 33, 130)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 239, 573)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1397)
[M::mem_pestat] mean and std.dev: (350.85, 304.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1809)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 236, 351)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 743)
[M::mem_pestat] mean and std.dev: (264.42, 138.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 939)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (397, 791, 2412)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6442)
[M::mem_pestat] mean and std.dev: (1306.16, 1415.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8457)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 318, 692)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1674)
[M::mem_pestat] mean and std.dev: (323.87, 220.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2165)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 12, #reads = 1075964 mem = 536879049 peak = 890232832
[M::process] read 705176 sequences (100000083 bp) in 3.349 CPU sec, 3.625 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (92, 284946, 23, 102)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 273, 409)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 861)
[M::mem_pestat] mean and std.dev: (255.58, 121.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1087)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 234, 349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 739)
[M::mem_pestat] mean and std.dev: (262.37, 137.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 934)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (782, 1239, 2504)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5948)
[M::mem_pestat] mean and std.dev: (1719.30, 1434.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7670)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 258, 536)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1254)
[M::mem_pestat] mean and std.dev: (295.13, 194.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1613)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704714 reads in 201.871 CPU sec, 6.411 real sec
[M::process] read 704212 sequences (100000104 bp) in 2.212 CPU sec, 2.220 real sec...
[M::mem_process_seqs] Processed 705524 reads in 139.130 CPU sec, 4.400 real sec
sorting block 13, #reads = 1079207 mem = 536881327 peak = 890232832
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (116, 284571, 41, 101)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 410, 1240)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3320)
[M::mem_pestat] mean and std.dev: (621.61, 699.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4360)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 235, 351)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 745)
[M::mem_pestat] mean and std.dev: (263.72, 138.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 942)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 493, 1730)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4826)
[M::mem_pestat] mean and std.dev: (807.65, 1038.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6374)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 236, 422)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 938)
[M::mem_pestat] mean and std.dev: (248.55, 137.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1196)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703590 sequences (100000084 bp) in 3.688 CPU sec, 3.974 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (114, 284724, 43, 88)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 282, 578)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1400)
[M::mem_pestat] mean and std.dev: (302.43, 217.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1811)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 238, 355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 753)
[M::mem_pestat] mean and std.dev: (266.36, 139.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 952)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (135, 371, 1618)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4584)
[M::mem_pestat] mean and std.dev: (755.10, 945.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6067)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 336, 996)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2570)
[M::mem_pestat] mean and std.dev: (457.84, 418.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3357)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 705176 reads in 199.354 CPU sec, 6.340 real sec
[M::mem_process_seqs] Processed 704212 reads in 133.146 CPU sec, 4.202 real sec
[M::process] read 702506 sequences (100000261 bp) in 2.814 CPU sec, 2.915 real sec...
sorting block 14, #reads = 1080741 mem = 536884668 peak = 890232832
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 284557, 41, 99)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 282, 1585)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4407)
[M::mem_pestat] mean and std.dev: (772.87, 1110.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5818)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 239, 357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 759)
[M::mem_pestat] mean and std.dev: (267.97, 140.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 960)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (234, 512, 1348)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3576)
[M::mem_pestat] mean and std.dev: (550.09, 509.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4690)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 350, 590)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1338)
[M::mem_pestat] mean and std.dev: (385.54, 242.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1712)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701914 sequences (100000270 bp) in 3.724 CPU sec, 4.171 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (91, 284441, 26, 113)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 393, 1381)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3761)
[M::mem_pestat] mean and std.dev: (677.51, 778.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4951)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 243, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 770)
[M::mem_pestat] mean and std.dev: (271.65, 142.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 974)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (122, 836, 2073)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5975)
[M::mem_pestat] mean and std.dev: (1126.54, 1281.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7926)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 352, 605)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1379)
[M::mem_pestat] mean and std.dev: (375.72, 228.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1766)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703590 reads in 190.803 CPU sec, 6.103 real sec
[M::mem_process_seqs] Processed 702506 reads in 132.160 CPU sec, 4.188 real sec
sorting block 15, #reads = 1080519 mem = 536882926 peak = 890232832
[M::process] read 701584 sequences (100000140 bp) in 3.859 CPU sec, 4.183 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (105, 283699, 45, 119)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 262, 570)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1376)
[M::mem_pestat] mean and std.dev: (336.27, 257.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1779)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 245, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 777)
[M::mem_pestat] mean and std.dev: (273.25, 142.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 983)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 611, 1462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4074)
[M::mem_pestat] mean and std.dev: (748.71, 723.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5380)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 279, 604)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1428)
[M::mem_pestat] mean and std.dev: (313.57, 228.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1840)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 16, #reads = 1080808 mem = 536879319 peak = 890232832
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (121, 283808, 47, 127)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (252, 476, 1070)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2706)
[M::mem_pestat] mean and std.dev: (531.05, 454.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3524)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 245, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 781)
[M::mem_pestat] mean and std.dev: (274.32, 144.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 988)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (570, 1612, 3203)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8469)
[M::mem_pestat] mean and std.dev: (1882.85, 1636.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11102)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (235, 364, 984)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2482)
[M::mem_pestat] mean and std.dev: (535.03, 494.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3231)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701914 reads in 195.047 CPU sec, 6.242 real sec
[M::process] read 701016 sequences (100000026 bp) in 3.428 CPU sec, 3.641 real sec...
[M::mem_process_seqs] Processed 701584 reads in 133.154 CPU sec, 4.235 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (107, 283726, 53, 122)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 303, 467)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1003)
[M::mem_pestat] mean and std.dev: (323.31, 183.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1271)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 246, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 778)
[M::mem_pestat] mean and std.dev: (274.63, 143.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 984)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (474, 1054, 2987)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8013)
[M::mem_pestat] mean and std.dev: (1778.89, 1792.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10526)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (310, 428, 886)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2038)
[M::mem_pestat] mean and std.dev: (569.41, 474.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2614)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 17, #reads = 1079471 mem = 536887363 peak = 890232832
[M::process] read 701254 sequences (100000263 bp) in 3.983 CPU sec, 4.320 real sec...
[M::mem_process_seqs] Processed 701016 reads in 111.272 CPU sec, 3.653 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (137, 284002, 36, 134)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 302, 705)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1769)
[M::mem_pestat] mean and std.dev: (445.99, 434.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2301)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 244, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 772)
[M::mem_pestat] mean and std.dev: (273.40, 143.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 976)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (512, 982, 3630)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9866)
[M::mem_pestat] mean and std.dev: (2048.69, 2223.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12984)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 309, 581)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1401)
[M::mem_pestat] mean and std.dev: (311.66, 209.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1811)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701254 reads in 111.658 CPU sec, 3.660 real sec
sorting block 18, #reads = 1077834 mem = 536879119 peak = 890232832
[M::process] read 700926 sequences (100000080 bp) in 3.990 CPU sec, 4.383 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (111, 283677, 59, 99)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 347, 1012)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2722)
[M::mem_pestat] mean and std.dev: (519.82, 502.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3577)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 245, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 769)
[M::mem_pestat] mean and std.dev: (273.19, 141.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 972)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (338, 1167, 2468)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6728)
[M::mem_pestat] mean and std.dev: (1251.06, 1386.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8858)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 301, 667)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1679)
[M::mem_pestat] mean and std.dev: (385.41, 327.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2185)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701202 sequences (100000131 bp) in 3.217 CPU sec, 3.552 real sec...
[M::mem_process_seqs] Processed 700926 reads in 114.797 CPU sec, 3.701 real sec
sorting block 19, #reads = 1078030 mem = 536876680 peak = 890232832
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (114, 284092, 45, 114)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 291, 764)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1964)
[M::mem_pestat] mean and std.dev: (405.93, 392.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2564)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 243, 357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 751)
[M::mem_pestat] mean and std.dev: (269.85, 138.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 948)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (243, 593, 1258)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3288)
[M::mem_pestat] mean and std.dev: (564.92, 517.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4303)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (235, 330, 502)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1036)
[M::mem_pestat] mean and std.dev: (341.10, 165.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1303)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701202 reads in 112.222 CPU sec, 3.607 real sec
[M::process] read 701000 sequences (100000149 bp) in 3.913 CPU sec, 4.226 real sec...
sorting block 20, #reads = 1077266 mem = 536878441 peak = 890232832
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (92, 283890, 42, 101)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 247, 801)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2029)
[M::mem_pestat] mean and std.dev: (398.58, 359.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2643)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 243, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 754)
[M::mem_pestat] mean and std.dev: (269.87, 138.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 952)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (588, 1316, 2649)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6771)
[M::mem_pestat] mean and std.dev: (1804.78, 1533.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8832)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 291, 615)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1473)
[M::mem_pestat] mean and std.dev: (351.30, 241.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1902)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700638 sequences (100000187 bp) in 2.934 CPU sec, 3.115 real sec...
[M::mem_process_seqs] Processed 701000 reads in 113.470 CPU sec, 3.649 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (105, 282930, 35, 118)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 306, 643)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1521)
[M::mem_pestat] mean and std.dev: (386.04, 315.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1960)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 243, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 752)
[M::mem_pestat] mean and std.dev: (270.42, 139.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 949)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (389, 1056, 4213)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 11861)
[M::mem_pestat] mean and std.dev: (2071.83, 2267.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 15685)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 330, 663)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1607)
[M::mem_pestat] mean and std.dev: (386.24, 285.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2079)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700204 sequences (100000006 bp) in 3.437 CPU sec, 3.695 real sec...
[M::mem_process_seqs] Processed 700638 reads in 114.699 CPU sec, 3.678 real sec
sorting block 21, #reads = 1077679 mem = 536880170 peak = 890232832
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (83, 283471, 47, 93)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 258, 417)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 917)
[M::mem_pestat] mean and std.dev: (270.10, 161.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1167)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 246, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 756)
[M::mem_pestat] mean and std.dev: (271.90, 139.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 954)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (287, 1036, 1880)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5066)
[M::mem_pestat] mean and std.dev: (1164.67, 1009.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6659)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 339, 587)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1385)
[M::mem_pestat] mean and std.dev: (343.88, 201.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1784)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700234 sequences (100000104 bp) in 3.567 CPU sec, 3.796 real sec...
[M::mem_process_seqs] Processed 700204 reads in 112.973 CPU sec, 3.636 real sec
sorting block 22, #reads = 1076322 mem = 536884091 peak = 890232832
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (115, 283419, 50, 110)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 296, 547)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1277)
[M::mem_pestat] mean and std.dev: (335.77, 251.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1642)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 246, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 759)
[M::mem_pestat] mean and std.dev: (272.68, 139.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 958)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (489, 1034, 4322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 11988)
[M::mem_pestat] mean and std.dev: (2489.42, 2612.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 15821)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 295, 735)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1851)
[M::mem_pestat] mean and std.dev: (435.62, 376.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2409)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699646 sequences (100000073 bp) in 3.623 CPU sec, 3.868 real sec...
[M::mem_process_seqs] Processed 700234 reads in 111.813 CPU sec, 3.589 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (93, 282834, 50, 123)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 256, 656)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1602)
[M::mem_pestat] mean and std.dev: (353.32, 292.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2075)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 248, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 771)
[M::mem_pestat] mean and std.dev: (274.81, 141.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 974)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (685, 1583, 2948)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7474)
[M::mem_pestat] mean and std.dev: (1881.25, 1755.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9737)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 260, 591)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1419)
[M::mem_pestat] mean and std.dev: (339.53, 252.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1833)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699646 reads in 110.427 CPU sec, 3.554 real sec
[M::process] read 699132 sequences (100000266 bp) in 3.734 CPU sec, 4.010 real sec...
sorting block 23, #reads = 1076444 mem = 536880810 peak = 890232832
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (98, 283069, 43, 90)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 309, 522)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1166)
[M::mem_pestat] mean and std.dev: (312.38, 183.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1488)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 249, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 772)
[M::mem_pestat] mean and std.dev: (275.79, 142.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 975)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 492, 2058)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5836)
[M::mem_pestat] mean and std.dev: (920.98, 1112.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7725)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 290, 676)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1618)
[M::mem_pestat] mean and std.dev: (422.23, 339.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2089)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699132 reads in 110.564 CPU sec, 3.548 real sec
[M::process] read 699418 sequences (100000188 bp) in 3.417 CPU sec, 3.623 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (107, 283373, 45, 120)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 337, 764)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1970)
[M::mem_pestat] mean and std.dev: (401.51, 380.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2573)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 249, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 775)
[M::mem_pestat] mean and std.dev: (276.16, 142.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 979)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 395, 2056)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5830)
[M::mem_pestat] mean and std.dev: (1184.16, 1585.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7717)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 323, 483)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1039)
[M::mem_pestat] mean and std.dev: (326.67, 183.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1317)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699418 reads in 106.524 CPU sec, 3.427 real sec
sorting block 24, #reads = 1075385 mem = 536877602 peak = 890232832
[M::process] read 700008 sequences (100000062 bp) in 4.203 CPU sec, 4.558 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (107, 283239, 37, 113)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 234, 722)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1806)
[M::mem_pestat] mean and std.dev: (302.49, 241.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2348)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 246, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 774)
[M::mem_pestat] mean and std.dev: (275.04, 143.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 978)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (520, 1114, 4211)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 11593)
[M::mem_pestat] mean and std.dev: (2529.22, 2898.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 15284)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 345, 712)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1744)
[M::mem_pestat] mean and std.dev: (416.10, 315.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2260)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703662 sequences (100000023 bp) in 3.157 CPU sec, 3.303 real sec...
[M::mem_process_seqs] Processed 700008 reads in 111.005 CPU sec, 3.555 real sec
sorting block 25, #reads = 1076109 mem = 536881069 peak = 890232832
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (104, 284548, 56, 98)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 268, 525)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1243)
[M::mem_pestat] mean and std.dev: (320.32, 222.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1602)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 238, 355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 753)
[M::mem_pestat] mean and std.dev: (266.52, 139.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 952)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (146, 737, 1189)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3275)
[M::mem_pestat] mean and std.dev: (742.12, 731.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4318)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 339, 1106)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2978)
[M::mem_pestat] mean and std.dev: (528.38, 547.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3914)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 707446 sequences (100000017 bp) in 3.153 CPU sec, 3.414 real sec...
[M::mem_process_seqs] Processed 703662 reads in 113.185 CPU sec, 3.636 real sec
[M::process] read 707238 sequences (100000113 bp) in 2.910 CPU sec, 3.129 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (98, 285319, 35, 105)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 303, 444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 954)
[M::mem_pestat] mean and std.dev: (293.52, 164.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1209)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 229, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 726)
[M::mem_pestat] mean and std.dev: (257.40, 134.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 918)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (613, 1484, 3311)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8707)
[M::mem_pestat] mean and std.dev: (2112.50, 2079.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11405)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 291, 428)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 972)
[M::mem_pestat] mean and std.dev: (297.02, 166.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1244)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705636 sequences (100000206 bp) in 1.698 CPU sec, 1.700 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (100, 285855, 41, 92)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (144, 270, 406)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 930)
[M::mem_pestat] mean and std.dev: (273.03, 169.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1192)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 230, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 730)
[M::mem_pestat] mean and std.dev: (258.27, 134.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 923)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (437, 777, 1475)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3551)
[M::mem_pestat] mean and std.dev: (869.34, 606.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4589)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 308, 602)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1378)
[M::mem_pestat] mean and std.dev: (313.95, 173.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1766)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704420 sequences (100000279 bp) in 1.589 CPU sec, 1.589 real sec...
[M::mem_process_seqs] Processed 707446 reads in 195.092 CPU sec, 6.135 real sec
sorting block 26, #reads = 1077282 mem = 536879674 peak = 890232832
[M::mem_process_seqs] Processed 707238 reads in 135.880 CPU sec, 4.291 real sec
sorting block 27, #reads = 1080923 mem = 536878210 peak = 1019568128
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (98, 285051, 43, 99)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (226, 409, 1100)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2848)
[M::mem_pestat] mean and std.dev: (552.43, 474.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3722)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 235, 349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 739)
[M::mem_pestat] mean and std.dev: (262.16, 136.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 934)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (749, 1139, 2188)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5066)
[M::mem_pestat] mean and std.dev: (1300.40, 1115.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6505)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 326, 681)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1657)
[M::mem_pestat] mean and std.dev: (396.75, 317.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2145)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703288 sequences (100000160 bp) in 3.774 CPU sec, 4.053 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (109, 284510, 28, 139)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 276, 473)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1021)
[M::mem_pestat] mean and std.dev: (310.47, 191.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1295)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 237, 352)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 746)
[M::mem_pestat] mean and std.dev: (264.74, 137.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 943)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (543, 902, 2889)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7581)
[M::mem_pestat] mean and std.dev: (1882.04, 2075.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10184)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 303, 828)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2068)
[M::mem_pestat] mean and std.dev: (429.38, 361.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2688)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 705636 reads in 193.740 CPU sec, 6.126 real sec
[M::process] read 702480 sequences (100000179 bp) in 2.603 CPU sec, 2.661 real sec...
[M::mem_process_seqs] Processed 704420 reads in 133.140 CPU sec, 4.188 real sec
sorting block 28, #reads = 1081274 mem = 536879770 peak = 1019568128
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (106, 284752, 52, 110)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 276, 655)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1601)
[M::mem_pestat] mean and std.dev: (375.79, 288.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2074)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 241, 357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 757)
[M::mem_pestat] mean and std.dev: (268.10, 138.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 957)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (356, 756, 2309)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6215)
[M::mem_pestat] mean and std.dev: (962.94, 997.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8168)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 322, 560)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1264)
[M::mem_pestat] mean and std.dev: (337.83, 212.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1616)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701806 sequences (100000008 bp) in 3.220 CPU sec, 3.440 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (87, 283766, 53, 105)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 302, 803)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2069)
[M::mem_pestat] mean and std.dev: (427.82, 437.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2702)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 242, 357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 755)
[M::mem_pestat] mean and std.dev: (269.04, 138.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 954)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (349, 858, 1835)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4807)
[M::mem_pestat] mean and std.dev: (945.39, 737.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6293)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (243, 353, 945)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2349)
[M::mem_pestat] mean and std.dev: (572.53, 497.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3051)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701430 sequences (100000002 bp) in 2.099 CPU sec, 2.105 real sec...
[M::mem_process_seqs] Processed 703288 reads in 192.793 CPU sec, 6.102 real sec
sorting block 29, #reads = 1079035 mem = 536883390 peak = 1019568128
[M::mem_process_seqs] Processed 702480 reads in 134.378 CPU sec, 4.246 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (92, 284048, 32, 104)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 313, 683)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1645)
[M::mem_pestat] mean and std.dev: (399.73, 309.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2126)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 245, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 768)
[M::mem_pestat] mean and std.dev: (271.54, 140.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 971)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 467, 1076)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2888)
[M::mem_pestat] mean and std.dev: (647.67, 709.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3794)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 265, 589)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1357)
[M::mem_pestat] mean and std.dev: (349.00, 239.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1741)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701258 sequences (100000219 bp) in 3.120 CPU sec, 3.412 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (110, 283906, 43, 121)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 234, 449)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1033)
[M::mem_pestat] mean and std.dev: (283.76, 190.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1325)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 245, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 766)
[M::mem_pestat] mean and std.dev: (272.31, 140.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 968)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (571, 1180, 2813)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7297)
[M::mem_pestat] mean and std.dev: (1551.44, 1366.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9539)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 412, 534)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1158)
[M::mem_pestat] mean and std.dev: (374.16, 219.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1470)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701468 sequences (100000172 bp) in 1.813 CPU sec, 1.820 real sec...
[M::mem_process_seqs] Processed 701806 reads in 194.791 CPU sec, 6.181 real sec
sorting block 30, #reads = 1078574 mem = 536883045 peak = 1019568128
[M::mem_process_seqs] Processed 701430 reads in 134.517 CPU sec, 4.267 real sec
sorting block 31, #reads = 1077910 mem = 536881502 peak = 1021329408
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (145, 283452, 31, 91)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 326, 543)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1247)
[M::mem_pestat] mean and std.dev: (352.73, 231.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1599)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 245, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 769)
[M::mem_pestat] mean and std.dev: (272.69, 141.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 972)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (692, 1891, 2990)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7586)
[M::mem_pestat] mean and std.dev: (1603.39, 1345.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9884)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 311, 586)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1368)
[M::mem_pestat] mean and std.dev: (336.91, 231.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1759)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700630 sequences (100000294 bp) in 3.172 CPU sec, 3.353 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (110, 283768, 33, 118)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 337, 577)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1339)
[M::mem_pestat] mean and std.dev: (382.69, 262.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1720)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 244, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 754)
[M::mem_pestat] mean and std.dev: (270.31, 139.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 952)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 526, 1957)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5533)
[M::mem_pestat] mean and std.dev: (1266.18, 1511.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7321)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 302, 539)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1271)
[M::mem_pestat] mean and std.dev: (339.57, 216.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1637)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700720 sequences (100000017 bp) in 2.411 CPU sec, 2.419 real sec...
[M::mem_process_seqs] Processed 701258 reads in 194.344 CPU sec, 6.136 real sec
[M::mem_process_seqs] Processed 701468 reads in 133.655 CPU sec, 4.218 real sec
sorting block 32, #reads = 1078416 mem = 536881702 peak = 1021329408
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (133, 283354, 44, 104)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 289, 741)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1839)
[M::mem_pestat] mean and std.dev: (380.66, 309.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2388)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 245, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 758)
[M::mem_pestat] mean and std.dev: (272.02, 139.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 957)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (419, 1076, 2001)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5165)
[M::mem_pestat] mean and std.dev: (1190.17, 974.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6747)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 331, 545)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1277)
[M::mem_pestat] mean and std.dev: (338.60, 213.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1643)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700450 sequences (100000147 bp) in 3.721 CPU sec, 3.974 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (132, 283189, 54, 107)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 336, 663)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1593)
[M::mem_pestat] mean and std.dev: (390.03, 311.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2058)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 244, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 752)
[M::mem_pestat] mean and std.dev: (270.60, 138.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 949)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 646, 1464)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4078)
[M::mem_pestat] mean and std.dev: (875.83, 873.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5385)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 340, 576)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1330)
[M::mem_pestat] mean and std.dev: (394.44, 290.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1707)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700630 reads in 195.010 CPU sec, 6.167 real sec
[M::mem_process_seqs] Processed 700720 reads in 135.887 CPU sec, 4.277 real sec
[M::process] read 699978 sequences (100000227 bp) in 2.993 CPU sec, 3.110 real sec...
sorting block 33, #reads = 1077288 mem = 536879262 peak = 1021329408
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (108, 283796, 67, 109)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 452, 940)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2414)
[M::mem_pestat] mean and std.dev: (538.68, 517.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3151)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 245, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 758)
[M::mem_pestat] mean and std.dev: (271.58, 139.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 957)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 734, 1731)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4773)
[M::mem_pestat] mean and std.dev: (915.60, 978.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6294)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 308, 858)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2162)
[M::mem_pestat] mean and std.dev: (497.67, 460.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2814)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700266 sequences (100000085 bp) in 3.651 CPU sec, 3.889 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (131, 283145, 42, 114)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 302, 521)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1203)
[M::mem_pestat] mean and std.dev: (290.43, 167.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1544)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 246, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 762)
[M::mem_pestat] mean and std.dev: (273.05, 140.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 962)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (305, 887, 2066)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5588)
[M::mem_pestat] mean and std.dev: (1252.58, 1324.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7349)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 325, 751)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1853)
[M::mem_pestat] mean and std.dev: (436.32, 382.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2404)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700450 reads in 196.790 CPU sec, 6.244 real sec
sorting block 34, #reads = 1077442 mem = 536883157 peak = 1021329408
[M::mem_process_seqs] Processed 699978 reads in 136.954 CPU sec, 4.314 real sec
[M::process] read 700234 sequences (100000179 bp) in 3.386 CPU sec, 3.560 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (114, 283135, 43, 84)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 298, 649)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1579)
[M::mem_pestat] mean and std.dev: (352.98, 315.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2044)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 245, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 755)
[M::mem_pestat] mean and std.dev: (271.12, 138.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 953)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (494, 1270, 3513)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9551)
[M::mem_pestat] mean and std.dev: (1974.21, 1862.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12570)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 394, 1183)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3115)
[M::mem_pestat] mean and std.dev: (552.73, 551.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4081)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 35, #reads = 1076256 mem = 536879219 peak = 1021329408
[M::process] read 700222 sequences (100000006 bp) in 3.650 CPU sec, 3.916 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (109, 282942, 70, 123)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (228, 345, 1084)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2796)
[M::mem_pestat] mean and std.dev: (612.01, 586.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3652)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 246, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 762)
[M::mem_pestat] mean and std.dev: (272.97, 140.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 962)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (485, 886, 1670)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4040)
[M::mem_pestat] mean and std.dev: (980.08, 841.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5225)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 271, 442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 930)
[M::mem_pestat] mean and std.dev: (277.38, 134.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1174)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700266 reads in 198.692 CPU sec, 6.324 real sec
[M::mem_process_seqs] Processed 700234 reads in 139.219 CPU sec, 4.391 real sec
[M::process] read 700068 sequences (100000133 bp) in 3.690 CPU sec, 3.961 real sec...
sorting block 36, #reads = 1075782 mem = 536879180 peak = 1021329408
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (117, 283765, 54, 94)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 306, 675)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1693)
[M::mem_pestat] mean and std.dev: (421.34, 387.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2202)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 246, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 770)
[M::mem_pestat] mean and std.dev: (273.95, 142.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 973)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (455, 823, 1536)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3698)
[M::mem_pestat] mean and std.dev: (1028.38, 772.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4779)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 253, 444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 974)
[M::mem_pestat] mean and std.dev: (278.26, 157.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1239)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700262 sequences (100000157 bp) in 3.159 CPU sec, 3.347 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (91, 283602, 36, 118)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 292, 689)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1725)
[M::mem_pestat] mean and std.dev: (388.86, 334.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2243)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 246, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 765)
[M::mem_pestat] mean and std.dev: (273.70, 141.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 966)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (728, 1134, 1870)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4154)
[M::mem_pestat] mean and std.dev: (1162.44, 877.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5296)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 293, 616)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1456)
[M::mem_pestat] mean and std.dev: (335.77, 224.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1876)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700222 reads in 201.909 CPU sec, 6.433 real sec
[M::mem_process_seqs] Processed 700068 reads in 140.032 CPU sec, 4.414 real sec
sorting block 37, #reads = 1075257 mem = 536880187 peak = 1021329408
[M::process] read 704136 sequences (100000262 bp) in 3.006 CPU sec, 3.210 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (103, 283200, 36, 112)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 290, 591)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1367)
[M::mem_pestat] mean and std.dev: (351.56, 255.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1755)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 245, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 764)
[M::mem_pestat] mean and std.dev: (272.84, 141.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 965)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (306, 986, 1357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3459)
[M::mem_pestat] mean and std.dev: (763.87, 530.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4510)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 384, 691)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1661)
[M::mem_pestat] mean and std.dev: (484.21, 423.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2179)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706188 sequences (100000189 bp) in 3.360 CPU sec, 3.629 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (119, 283760, 42, 111)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 262, 396)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 838)
[M::mem_pestat] mean and std.dev: (250.44, 124.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1059)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 236, 350)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 740)
[M::mem_pestat] mean and std.dev: (263.58, 136.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 935)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (91, 678, 2049)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5965)
[M::mem_pestat] mean and std.dev: (1303.71, 1661.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7948)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (258, 354, 475)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 909)
[M::mem_pestat] mean and std.dev: (316.64, 123.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1126)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700262 reads in 198.975 CPU sec, 6.332 real sec
[M::mem_process_seqs] Processed 704136 reads in 141.581 CPU sec, 4.468 real sec
sorting block 38, #reads = 1075707 mem = 536875477 peak = 1021329408
[M::process] read 705704 sequences (100000057 bp) in 3.292 CPU sec, 3.506 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (95, 285402, 33, 100)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 445, 1450)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3982)
[M::mem_pestat] mean and std.dev: (776.02, 805.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5248)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 234, 348)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 738)
[M::mem_pestat] mean and std.dev: (261.35, 136.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 933)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (88, 627, 2037)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5935)
[M::mem_pestat] mean and std.dev: (1059.42, 1226.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7884)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 309, 946)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2462)
[M::mem_pestat] mean and std.dev: (447.36, 419.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3220)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 39, #reads = 1075389 mem = 536878512 peak = 1021329408
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (117, 285430, 40, 102)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (226, 361, 1108)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2872)
[M::mem_pestat] mean and std.dev: (675.79, 742.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3754)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 234, 349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 741)
[M::mem_pestat] mean and std.dev: (262.45, 137.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 937)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (245, 1274, 2299)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6407)
[M::mem_pestat] mean and std.dev: (1277.57, 1361.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8461)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 312, 550)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1260)
[M::mem_pestat] mean and std.dev: (309.00, 190.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1615)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704738 sequences (100000223 bp) in 3.621 CPU sec, 3.860 real sec...
[M::mem_process_seqs] Processed 706188 reads in 192.910 CPU sec, 6.165 real sec
[M::mem_process_seqs] Processed 705704 reads in 137.187 CPU sec, 4.338 real sec
sorting block 40, #reads = 1081587 mem = 536879338 peak = 1021329408
[M::process] read 704280 sequences (100000283 bp) in 3.896 CPU sec, 4.225 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (100, 284649, 42, 116)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 334, 1374)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3682)
[M::mem_pestat] mean and std.dev: (770.74, 872.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4836)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 236, 353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 751)
[M::mem_pestat] mean and std.dev: (264.49, 137.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 950)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (121, 635, 1031)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2851)
[M::mem_pestat] mean and std.dev: (604.75, 598.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3761)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (238, 388, 869)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2131)
[M::mem_pestat] mean and std.dev: (515.41, 437.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2762)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (92, 284419, 54, 104)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 250, 587)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1427)
[M::mem_pestat] mean and std.dev: (315.36, 247.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1847)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 238, 353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 749)
[M::mem_pestat] mean and std.dev: (265.71, 138.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 947)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (260, 640, 1500)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3980)
[M::mem_pestat] mean and std.dev: (698.61, 678.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5220)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (239, 360, 569)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1229)
[M::mem_pestat] mean and std.dev: (335.88, 163.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1559)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703198 sequences (100000133 bp) in 3.290 CPU sec, 3.444 real sec...
[M::mem_process_seqs] Processed 704738 reads in 195.343 CPU sec, 6.235 real sec
[M::mem_process_seqs] Processed 704280 reads in 136.973 CPU sec, 4.341 real sec
sorting block 41, #reads = 1080642 mem = 536878595 peak = 1021329408
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (91, 284173, 46, 80)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (270, 390, 1157)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2931)
[M::mem_pestat] mean and std.dev: (583.98, 536.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3818)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 241, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 760)
[M::mem_pestat] mean and std.dev: (268.66, 139.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 961)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (125, 698, 2594)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7532)
[M::mem_pestat] mean and std.dev: (1176.90, 1542.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10001)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 298, 463)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1009)
[M::mem_pestat] mean and std.dev: (277.56, 137.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1282)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702326 sequences (100000038 bp) in 3.962 CPU sec, 4.318 real sec...
[M::mem_process_seqs] Processed 703198 reads in 114.522 CPU sec, 3.747 real sec
sorting block 42, #reads = 1079884 mem = 536881904 peak = 1021329408
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (110, 284348, 67, 129)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 387, 1273)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3447)
[M::mem_pestat] mean and std.dev: (737.53, 757.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4534)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 243, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 767)
[M::mem_pestat] mean and std.dev: (271.11, 140.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 970)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (348, 801, 1694)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4386)
[M::mem_pestat] mean and std.dev: (887.64, 879.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5732)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 268, 740)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1846)
[M::mem_pestat] mean and std.dev: (418.13, 361.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2399)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702362 sequences (100000043 bp) in 3.681 CPU sec, 4.033 real sec...
[M::mem_process_seqs] Processed 702326 reads in 114.524 CPU sec, 3.732 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (97, 284012, 27, 123)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 285, 854)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2156)
[M::mem_pestat] mean and std.dev: (535.67, 534.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2807)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 244, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 768)
[M::mem_pestat] mean and std.dev: (271.49, 140.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 971)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (68, 534, 1237)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3575)
[M::mem_pestat] mean and std.dev: (888.59, 965.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4750)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 331, 1112)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2888)
[M::mem_pestat] mean and std.dev: (481.98, 410.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3776)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 43, #reads = 1080461 mem = 536881589 peak = 1021329408
[M::mem_process_seqs] Processed 702362 reads in 111.987 CPU sec, 3.640 real sec
[M::process] read 701662 sequences (100000245 bp) in 4.144 CPU sec, 4.520 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (125, 283591, 48, 117)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 340, 612)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1426)
[M::mem_pestat] mean and std.dev: (346.71, 206.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1833)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 244, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 768)
[M::mem_pestat] mean and std.dev: (272.36, 141.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 971)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 789, 3382)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9782)
[M::mem_pestat] mean and std.dev: (1817.27, 2482.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12982)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 343, 622)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1458)
[M::mem_pestat] mean and std.dev: (357.78, 231.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1876)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702030 sequences (100000011 bp) in 3.269 CPU sec, 3.443 real sec...
[M::mem_process_seqs] Processed 701662 reads in 111.962 CPU sec, 3.599 real sec
sorting block 44, #reads = 1078851 mem = 536877846 peak = 1021329408
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (114, 284027, 42, 103)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 413, 2289)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6443)
[M::mem_pestat] mean and std.dev: (1247.81, 1573.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8520)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 244, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 765)
[M::mem_pestat] mean and std.dev: (271.66, 140.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 967)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 809, 2135)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5957)
[M::mem_pestat] mean and std.dev: (1212.85, 1106.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7868)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 394, 1250)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3334)
[M::mem_pestat] mean and std.dev: (584.39, 550.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4376)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702030 reads in 113.066 CPU sec, 3.632 real sec
[M::process] read 703158 sequences (100000048 bp) in 3.561 CPU sec, 3.802 real sec...
sorting block 45, #reads = 1077938 mem = 536878125 peak = 1021329408
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (107, 284674, 32, 97)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 262, 920)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2402)
[M::mem_pestat] mean and std.dev: (500.74, 516.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3143)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 237, 351)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 739)
[M::mem_pestat] mean and std.dev: (265.30, 137.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 933)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 672, 4585)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13333)
[M::mem_pestat] mean and std.dev: (1935.34, 2194.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17707)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 362, 568)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1318)
[M::mem_pestat] mean and std.dev: (337.20, 213.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1693)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703158 reads in 111.494 CPU sec, 3.588 real sec
[M::process] read 701566 sequences (100000101 bp) in 3.671 CPU sec, 3.922 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (108, 283964, 50, 104)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 291, 770)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1960)
[M::mem_pestat] mean and std.dev: (396.11, 362.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2555)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 240, 353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 741)
[M::mem_pestat] mean and std.dev: (267.00, 137.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 935)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (234, 494, 1667)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4533)
[M::mem_pestat] mean and std.dev: (676.25, 737.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5966)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 433, 1451)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3899)
[M::mem_pestat] mean and std.dev: (849.90, 910.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5123)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701748 sequences (100000011 bp) in 3.164 CPU sec, 3.327 real sec...
[M::mem_process_seqs] Processed 701566 reads in 108.082 CPU sec, 3.478 real sec
sorting block 46, #reads = 1078112 mem = 536879439 peak = 1021329408
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (116, 283292, 56, 112)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 301, 923)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2445)
[M::mem_pestat] mean and std.dev: (577.80, 576.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3206)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 240, 353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 741)
[M::mem_pestat] mean and std.dev: (267.05, 137.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 935)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (538, 1087, 2567)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6625)
[M::mem_pestat] mean and std.dev: (1680.96, 1808.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8913)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 331, 674)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1666)
[M::mem_pestat] mean and std.dev: (366.23, 301.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2162)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700794 sequences (100000244 bp) in 3.599 CPU sec, 3.853 real sec...
[M::mem_process_seqs] Processed 701748 reads in 115.520 CPU sec, 3.713 real sec
sorting block 47, #reads = 1075996 mem = 536877799 peak = 1021329408
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (93, 283471, 46, 110)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 314, 884)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2258)
[M::mem_pestat] mean and std.dev: (507.05, 506.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2945)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 243, 354)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 740)
[M::mem_pestat] mean and std.dev: (268.18, 136.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 933)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 578, 2433)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6955)
[M::mem_pestat] mean and std.dev: (1080.40, 1358.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9216)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 302, 760)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1828)
[M::mem_pestat] mean and std.dev: (395.73, 350.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2362)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700794 reads in 114.102 CPU sec, 3.655 real sec
[M::process] read 701032 sequences (100000123 bp) in 3.589 CPU sec, 3.843 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (108, 282749, 47, 126)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 260, 718)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1786)
[M::mem_pestat] mean and std.dev: (351.31, 293.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2320)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 242, 355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 745)
[M::mem_pestat] mean and std.dev: (267.96, 136.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 940)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (579, 911, 3393)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9021)
[M::mem_pestat] mean and std.dev: (2073.09, 2267.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11835)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 301, 506)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1162)
[M::mem_pestat] mean and std.dev: (313.07, 189.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1490)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701032 reads in 109.408 CPU sec, 3.522 real sec
[M::process] read 700436 sequences (100000195 bp) in 3.402 CPU sec, 3.595 real sec...
sorting block 48, #reads = 1076715 mem = 536887456 peak = 1021329408
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (136, 283647, 32, 129)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 358, 859)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2133)
[M::mem_pestat] mean and std.dev: (484.62, 448.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2770)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 243, 354)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 740)
[M::mem_pestat] mean and std.dev: (268.39, 135.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 933)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (362, 708, 1907)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4997)
[M::mem_pestat] mean and std.dev: (1058.90, 1019.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6542)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 324, 462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1006)
[M::mem_pestat] mean and std.dev: (293.43, 154.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1278)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700436 reads in 112.670 CPU sec, 3.612 real sec
[M::process] read 700436 sequences (100000152 bp) in 3.521 CPU sec, 3.739 real sec...
sorting block 49, #reads = 1075875 mem = 536879259 peak = 1021329408
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (85, 283551, 28, 124)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 256, 431)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 909)
[M::mem_pestat] mean and std.dev: (283.40, 132.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1148)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 244, 356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 746)
[M::mem_pestat] mean and std.dev: (269.24, 136.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 941)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (446, 669, 1337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3119)
[M::mem_pestat] mean and std.dev: (818.27, 631.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4010)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 344, 936)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2384)
[M::mem_pestat] mean and std.dev: (471.64, 431.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3108)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700436 reads in 107.564 CPU sec, 3.466 real sec
[M::process] read 700024 sequences (100000113 bp) in 3.370 CPU sec, 3.549 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (90, 283504, 49, 108)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 401, 1032)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2722)
[M::mem_pestat] mean and std.dev: (570.40, 560.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3567)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 245, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 755)
[M::mem_pestat] mean and std.dev: (271.26, 138.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 953)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (410, 1457, 1957)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5051)
[M::mem_pestat] mean and std.dev: (1336.02, 1279.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6598)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 273, 522)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1158)
[M::mem_pestat] mean and std.dev: (300.01, 184.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1476)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700024 reads in 109.318 CPU sec, 3.517 real sec
[M::process] read 700296 sequences (100000244 bp) in 3.404 CPU sec, 3.603 real sec...
sorting block 50, #reads = 1075806 mem = 536880395 peak = 1021329408
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (87, 283293, 58, 110)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 310, 702)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1732)
[M::mem_pestat] mean and std.dev: (395.39, 323.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2247)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 245, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 761)
[M::mem_pestat] mean and std.dev: (272.24, 140.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 961)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (484, 1182, 1992)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5008)
[M::mem_pestat] mean and std.dev: (1312.45, 1058.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6516)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (260, 417, 1191)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3053)
[M::mem_pestat] mean and std.dev: (617.61, 577.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3984)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700134 sequences (100000183 bp) in 3.266 CPU sec, 3.413 real sec...
[M::mem_process_seqs] Processed 700296 reads in 107.693 CPU sec, 3.462 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (118, 283460, 37, 108)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (146, 311, 967)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2609)
[M::mem_pestat] mean and std.dev: (517.50, 567.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3430)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 246, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 765)
[M::mem_pestat] mean and std.dev: (273.60, 141.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 966)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (459, 1019, 2271)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5895)
[M::mem_pestat] mean and std.dev: (1250.32, 1184.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7707)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 418, 623)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1429)
[M::mem_pestat] mean and std.dev: (440.78, 308.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1832)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700134 reads in 107.093 CPU sec, 3.443 real sec
sorting block 51, #reads = 1075296 mem = 536881630 peak = 1021329408
[M::process] read 706440 sequences (100000143 bp) in 3.549 CPU sec, 3.738 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (102, 285383, 36, 88)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 295, 996)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2656)
[M::mem_pestat] mean and std.dev: (508.84, 565.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3486)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 227, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 709)
[M::mem_pestat] mean and std.dev: (255.75, 133.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 895)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (134, 389, 1419)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3989)
[M::mem_pestat] mean and std.dev: (648.62, 864.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5274)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 372, 942)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2476)
[M::mem_pestat] mean and std.dev: (458.21, 487.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3243)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 710430 sequences (100000082 bp) in 3.084 CPU sec, 3.181 real sec...
[M::mem_process_seqs] Processed 706440 reads in 114.923 CPU sec, 3.677 real sec
sorting block 52, #reads = 1075815 mem = 536879779 peak = 1021329408
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (99, 286612, 33, 117)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 322, 1107)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3001)
[M::mem_pestat] mean and std.dev: (689.01, 797.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3948)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 218, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 672)
[M::mem_pestat] mean and std.dev: (245.63, 128.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 847)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (263, 1586, 2784)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7826)
[M::mem_pestat] mean and std.dev: (1847.75, 2026.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10347)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 338, 677)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1617)
[M::mem_pestat] mean and std.dev: (410.84, 292.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2087)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 707064 sequences (100000004 bp) in 3.380 CPU sec, 3.558 real sec...
[M::mem_process_seqs] Processed 710430 reads in 112.611 CPU sec, 3.602 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (83, 286116, 41, 117)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 287, 635)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1521)
[M::mem_pestat] mean and std.dev: (350.32, 266.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1964)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 226, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 712)
[M::mem_pestat] mean and std.dev: (255.51, 133.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 899)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 674, 1957)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5575)
[M::mem_pestat] mean and std.dev: (1032.83, 1114.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7384)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 306, 557)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1325)
[M::mem_pestat] mean and std.dev: (337.04, 246.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1709)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705878 sequences (100000194 bp) in 3.352 CPU sec, 3.539 real sec...
[M::mem_process_seqs] Processed 707064 reads in 103.492 CPU sec, 3.321 real sec
sorting block 53, #reads = 1079066 mem = 536881553 peak = 1021329408
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (96, 285433, 34, 105)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 250, 559)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1377)
[M::mem_pestat] mean and std.dev: (355.08, 280.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1786)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 230, 345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 731)
[M::mem_pestat] mean and std.dev: (260.48, 137.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 924)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (514, 997, 2210)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5602)
[M::mem_pestat] mean and std.dev: (1428.77, 1395.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7298)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 361, 854)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2126)
[M::mem_pestat] mean and std.dev: (516.05, 435.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2762)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704926 sequences (100000075 bp) in 3.399 CPU sec, 3.578 real sec...
[M::mem_process_seqs] Processed 705878 reads in 103.622 CPU sec, 3.318 real sec
sorting block 54, #reads = 1079322 mem = 536879476 peak = 1021329408
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (113, 285349, 41, 101)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 319, 685)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1693)
[M::mem_pestat] mean and std.dev: (353.67, 270.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2197)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 233, 348)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 736)
[M::mem_pestat] mean and std.dev: (262.50, 138.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 930)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (360, 1048, 1666)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4278)
[M::mem_pestat] mean and std.dev: (1056.59, 863.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5584)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 301, 812)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2024)
[M::mem_pestat] mean and std.dev: (399.12, 331.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2630)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704926 reads in 99.662 CPU sec, 3.224 real sec
[M::process] read 704264 sequences (100000150 bp) in 3.525 CPU sec, 3.699 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (113, 285488, 40, 83)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 268, 789)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2017)
[M::mem_pestat] mean and std.dev: (493.64, 516.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2631)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 235, 352)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 746)
[M::mem_pestat] mean and std.dev: (265.24, 140.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 943)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (420, 629, 2146)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5598)
[M::mem_pestat] mean and std.dev: (1281.66, 1417.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7324)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (230, 367, 754)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1802)
[M::mem_pestat] mean and std.dev: (443.22, 365.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2326)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704264 reads in 100.753 CPU sec, 3.226 real sec
sorting block 55, #reads = 1078895 mem = 536878353 peak = 1021329408
[M::process] read 703476 sequences (100000095 bp) in 3.203 CPU sec, 3.332 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (115, 284819, 38, 138)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 369, 960)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2438)
[M::mem_pestat] mean and std.dev: (601.33, 576.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3177)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 237, 354)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 750)
[M::mem_pestat] mean and std.dev: (266.56, 140.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 948)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (260, 632, 2980)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8420)
[M::mem_pestat] mean and std.dev: (1765.50, 2194.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11140)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 362, 657)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1561)
[M::mem_pestat] mean and std.dev: (422.49, 316.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2013)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703476 reads in 102.012 CPU sec, 3.270 real sec
[M::process] read 702806 sequences (100000041 bp) in 3.301 CPU sec, 3.447 real sec...
sorting block 56, #reads = 1078722 mem = 536878579 peak = 1021329408
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (85, 284680, 64, 113)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 378, 945)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2469)
[M::mem_pestat] mean and std.dev: (551.15, 542.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3231)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 239, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 760)
[M::mem_pestat] mean and std.dev: (269.09, 141.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 961)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (297, 872, 3163)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8895)
[M::mem_pestat] mean and std.dev: (2057.91, 2661.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12705)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 304, 719)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1769)
[M::mem_pestat] mean and std.dev: (384.19, 355.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2294)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702806 reads in 105.663 CPU sec, 3.388 real sec
[M::process] read 702044 sequences (100000187 bp) in 3.208 CPU sec, 3.449 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (115, 283946, 52, 114)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (241, 395, 1376)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3646)
[M::mem_pestat] mean and std.dev: (718.61, 825.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4781)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 241, 357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 755)
[M::mem_pestat] mean and std.dev: (269.63, 140.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 954)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (269, 852, 2386)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6620)
[M::mem_pestat] mean and std.dev: (1306.06, 1280.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8737)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 290, 389)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 773)
[M::mem_pestat] mean and std.dev: (296.08, 131.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 965)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701926 sequences (100000112 bp) in 3.173 CPU sec, 3.330 real sec...
[M::mem_process_seqs] Processed 702044 reads in 105.208 CPU sec, 3.363 real sec
sorting block 57, #reads = 1077309 mem = 536880495 peak = 1021329408
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (102, 284224, 49, 128)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 288, 519)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1139)
[M::mem_pestat] mean and std.dev: (325.12, 208.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1449)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 242, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 759)
[M::mem_pestat] mean and std.dev: (270.66, 140.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 959)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (426, 913, 1964)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5040)
[M::mem_pestat] mean and std.dev: (1126.27, 953.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6578)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 327, 600)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1398)
[M::mem_pestat] mean and std.dev: (350.16, 255.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1797)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701266 sequences (100000138 bp) in 3.092 CPU sec, 3.177 real sec...
[M::mem_process_seqs] Processed 701926 reads in 106.023 CPU sec, 3.394 real sec
sorting block 58, #reads = 1074706 mem = 536877840 peak = 1021329408
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (104, 283362, 33, 117)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 266, 801)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2005)
[M::mem_pestat] mean and std.dev: (376.20, 345.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2607)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 243, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 763)
[M::mem_pestat] mean and std.dev: (271.80, 141.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 964)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (315, 548, 1222)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3036)
[M::mem_pestat] mean and std.dev: (740.44, 612.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3943)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 287, 672)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1582)
[M::mem_pestat] mean and std.dev: (337.69, 253.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2037)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701266 reads in 101.592 CPU sec, 3.265 real sec
[M::process] read 701618 sequences (100000006 bp) in 3.386 CPU sec, 3.537 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (99, 283986, 47, 107)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 282, 445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 967)
[M::mem_pestat] mean and std.dev: (267.05, 116.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1228)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 241, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 756)
[M::mem_pestat] mean and std.dev: (269.58, 140.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 955)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (320, 702, 1952)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5216)
[M::mem_pestat] mean and std.dev: (960.57, 983.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6848)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 404, 976)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2500)
[M::mem_pestat] mean and std.dev: (529.22, 510.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3262)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701618 reads in 103.674 CPU sec, 3.332 real sec
sorting block 59, #reads = 1073654 mem = 536880595 peak = 1021329408
[M::process] read 700852 sequences (100000081 bp) in 3.562 CPU sec, 3.752 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (112, 283583, 48, 128)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 233, 524)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1256)
[M::mem_pestat] mean and std.dev: (319.55, 270.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1622)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 243, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 760)
[M::mem_pestat] mean and std.dev: (271.59, 140.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 960)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (264, 542, 1258)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3246)
[M::mem_pestat] mean and std.dev: (680.95, 633.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4240)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (235, 340, 897)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2221)
[M::mem_pestat] mean and std.dev: (460.58, 411.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2883)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700840 sequences (100000272 bp) in 2.729 CPU sec, 2.850 real sec...
[M::mem_process_seqs] Processed 700852 reads in 106.150 CPU sec, 3.402 real sec
sorting block 60, #reads = 1074821 mem = 536881350 peak = 1021329408
[M::process] read 700872 sequences (100000012 bp) in 2.545 CPU sec, 2.667 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (91, 284023, 57, 83)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 282, 537)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1209)
[M::mem_pestat] mean and std.dev: (336.09, 237.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1545)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 243, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 757)
[M::mem_pestat] mean and std.dev: (270.87, 140.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 956)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (277, 801, 1902)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5152)
[M::mem_pestat] mean and std.dev: (1129.17, 1078.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6777)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 281, 513)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1121)
[M::mem_pestat] mean and std.dev: (315.88, 172.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1425)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700626 sequences (100000147 bp) in 1.709 CPU sec, 1.711 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (83, 283894, 43, 118)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 234, 646)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1634)
[M::mem_pestat] mean and std.dev: (320.67, 292.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2128)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 242, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 754)
[M::mem_pestat] mean and std.dev: (270.20, 139.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 952)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (234, 677, 2120)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5892)
[M::mem_pestat] mean and std.dev: (1104.83, 1127.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7778)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 354, 616)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1426)
[M::mem_pestat] mean and std.dev: (363.75, 244.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1831)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700744 sequences (100000166 bp) in 1.500 CPU sec, 1.502 real sec...
[M::mem_process_seqs] Processed 700840 reads in 186.349 CPU sec, 5.873 real sec
[M::mem_process_seqs] Processed 700872 reads in 125.459 CPU sec, 3.970 real sec
sorting block 61, #reads = 1074271 mem = 536880570 peak = 1021329408
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (109, 283680, 40, 103)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 278, 509)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1133)
[M::mem_pestat] mean and std.dev: (301.52, 176.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1445)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 243, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 755)
[M::mem_pestat] mean and std.dev: (270.96, 139.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 953)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (453, 729, 2601)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6897)
[M::mem_pestat] mean and std.dev: (1072.17, 1162.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9045)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 311, 532)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1202)
[M::mem_pestat] mean and std.dev: (354.82, 225.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1537)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700786 sequences (100000090 bp) in 2.875 CPU sec, 3.015 real sec...
[M::process] read 700448 sequences (100000045 bp) in 2.020 CPU sec, 2.017 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (121, 283231, 52, 134)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 277, 791)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2053)
[M::mem_pestat] mean and std.dev: (452.79, 415.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2684)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 243, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 757)
[M::mem_pestat] mean and std.dev: (271.18, 140.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 956)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (264, 664, 1306)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3390)
[M::mem_pestat] mean and std.dev: (692.85, 720.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4432)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 321, 565)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1287)
[M::mem_pestat] mean and std.dev: (347.84, 225.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1648)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700626 reads in 190.755 CPU sec, 6.028 real sec
[M::mem_process_seqs] Processed 700744 reads in 128.445 CPU sec, 4.069 real sec
sorting block 62, #reads = 1074487 mem = 536881778 peak = 1021329408
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (115, 284196, 44, 97)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (226, 313, 735)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1753)
[M::mem_pestat] mean and std.dev: (455.33, 372.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2262)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 243, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 760)
[M::mem_pestat] mean and std.dev: (271.64, 141.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 960)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (303, 598, 1159)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2871)
[M::mem_pestat] mean and std.dev: (710.30, 602.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3727)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 299, 551)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1253)
[M::mem_pestat] mean and std.dev: (341.36, 244.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1604)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 708584 sequences (100000144 bp) in 2.702 CPU sec, 2.885 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (122, 283128, 43, 102)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 301, 712)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1772)
[M::mem_pestat] mean and std.dev: (430.52, 399.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2302)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 245, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 770)
[M::mem_pestat] mean and std.dev: (274.00, 142.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 973)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (255, 672, 2062)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5676)
[M::mem_pestat] mean and std.dev: (1251.64, 1423.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7483)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 306, 513)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1147)
[M::mem_pestat] mean and std.dev: (301.76, 164.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1464)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 713794 sequences (100000261 bp) in 2.280 CPU sec, 2.280 real sec...
[M::mem_process_seqs] Processed 700786 reads in 183.434 CPU sec, 5.789 real sec
sorting block 63, #reads = 1073837 mem = 536886239 peak = 1021329408
[M::mem_process_seqs] Processed 700448 reads in 124.962 CPU sec, 3.959 real sec
sorting block 64, #reads = 1073493 mem = 536881415 peak = 1065615360
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (119, 286934, 35, 92)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 290, 529)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1231)
[M::mem_pestat] mean and std.dev: (327.21, 259.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1582)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 222, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 692)
[M::mem_pestat] mean and std.dev: (250.93, 131.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 873)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (242, 716, 1658)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4490)
[M::mem_pestat] mean and std.dev: (1048.03, 1041.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5906)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 315, 653)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1525)
[M::mem_pestat] mean and std.dev: (383.02, 306.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1961)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 711916 sequences (100000176 bp) in 3.016 CPU sec, 3.102 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (95, 288198, 40, 90)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 288, 766)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1918)
[M::mem_pestat] mean and std.dev: (445.95, 449.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2494)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (142, 210, 308)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 640)
[M::mem_pestat] mean and std.dev: (235.95, 120.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 806)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (232, 875, 2090)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5806)
[M::mem_pestat] mean and std.dev: (1172.76, 1362.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7664)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 264, 751)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1895)
[M::mem_pestat] mean and std.dev: (381.07, 350.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2467)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 709830 sequences (100000066 bp) in 2.400 CPU sec, 2.396 real sec...
[M::mem_process_seqs] Processed 708584 reads in 193.755 CPU sec, 6.113 real sec
[M::mem_process_seqs] Processed 713794 reads in 131.379 CPU sec, 4.155 real sec
sorting block 65, #reads = 1076575 mem = 536878093 peak = 1065615360
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (105, 287457, 42, 74)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 267, 766)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1956)
[M::mem_pestat] mean and std.dev: (418.99, 404.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2551)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 214, 316)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 658)
[M::mem_pestat] mean and std.dev: (241.05, 124.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 829)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 606, 1249)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3393)
[M::mem_pestat] mean and std.dev: (792.62, 751.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4465)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 307, 876)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2270)
[M::mem_pestat] mean and std.dev: (460.46, 474.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2967)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 708838 sequences (100000019 bp) in 3.487 CPU sec, 3.649 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (98, 287087, 42, 95)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 276, 623)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1559)
[M::mem_pestat] mean and std.dev: (371.72, 324.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2027)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 220, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 681)
[M::mem_pestat] mean and std.dev: (247.32, 128.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 859)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 595, 2130)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6084)
[M::mem_pestat] mean and std.dev: (1077.54, 1197.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8061)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 292, 513)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1141)
[M::mem_pestat] mean and std.dev: (308.65, 189.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1455)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 707812 sequences (100000127 bp) in 2.490 CPU sec, 2.487 real sec...
[M::mem_process_seqs] Processed 711916 reads in 198.837 CPU sec, 6.267 real sec
sorting block 66, #reads = 1076186 mem = 536879040 peak = 1065615360
[M::mem_process_seqs] Processed 709830 reads in 133.893 CPU sec, 4.222 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (87, 286994, 31, 87)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 302, 1529)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4159)
[M::mem_pestat] mean and std.dev: (759.94, 858.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5474)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 221, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 691)
[M::mem_pestat] mean and std.dev: (249.84, 129.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 872)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (602, 1286, 2399)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5993)
[M::mem_pestat] mean and std.dev: (1589.87, 1290.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7790)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 342, 1227)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3225)
[M::mem_pestat] mean and std.dev: (663.99, 754.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4224)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 707314 sequences (100000031 bp) in 3.127 CPU sec, 3.268 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (93, 286068, 32, 115)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 294, 1164)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3152)
[M::mem_pestat] mean and std.dev: (557.06, 645.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4146)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 224, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 705)
[M::mem_pestat] mean and std.dev: (253.47, 132.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 890)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (361, 631, 1244)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3010)
[M::mem_pestat] mean and std.dev: (787.07, 727.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3893)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 340, 695)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1663)
[M::mem_pestat] mean and std.dev: (368.70, 264.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2147)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 708838 reads in 192.763 CPU sec, 6.085 real sec
[M::process] read 707032 sequences (100000123 bp) in 2.596 CPU sec, 2.604 real sec...
sorting block 67, #reads = 1076500 mem = 536880592 peak = 1065615360
[M::mem_process_seqs] Processed 707812 reads in 130.245 CPU sec, 4.092 real sec
sorting block 68, #reads = 1075544 mem = 536878669 peak = 1065615360
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (78, 285949, 47, 115)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 395, 1074)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2790)
[M::mem_pestat] mean and std.dev: (640.86, 599.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3648)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 226, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 711)
[M::mem_pestat] mean and std.dev: (254.95, 133.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 898)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (309, 729, 1376)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3510)
[M::mem_pestat] mean and std.dev: (687.02, 537.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4577)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 342, 780)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1910)
[M::mem_pestat] mean and std.dev: (397.97, 320.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2475)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705544 sequences (100000045 bp) in 3.559 CPU sec, 3.725 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (120, 285753, 29, 85)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 326, 691)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1727)
[M::mem_pestat] mean and std.dev: (361.05, 270.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2245)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 228, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 721)
[M::mem_pestat] mean and std.dev: (256.66, 133.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 911)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 687, 4190)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12248)
[M::mem_pestat] mean and std.dev: (1820.48, 2539.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 16277)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 251, 469)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1071)
[M::mem_pestat] mean and std.dev: (268.86, 152.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1372)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 707314 reads in 189.147 CPU sec, 5.974 real sec
[M::mem_process_seqs] Processed 707032 reads in 129.237 CPU sec, 4.055 real sec
[M::process] read 704276 sequences (100000066 bp) in 2.753 CPU sec, 2.787 real sec...
sorting block 69, #reads = 1077200 mem = 536882617 peak = 1065615360
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (88, 285367, 55, 125)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 302, 478)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1076)
[M::mem_pestat] mean and std.dev: (297.37, 180.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1375)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 232, 347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 735)
[M::mem_pestat] mean and std.dev: (261.25, 136.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 929)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (250, 1019, 3427)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9781)
[M::mem_pestat] mean and std.dev: (1894.65, 2154.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12958)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (230, 347, 797)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1931)
[M::mem_pestat] mean and std.dev: (478.54, 409.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2498)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702970 sequences (100000206 bp) in 3.298 CPU sec, 3.490 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (113, 284507, 48, 114)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (249, 518, 1268)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3306)
[M::mem_pestat] mean and std.dev: (703.85, 765.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4325)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 235, 352)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 746)
[M::mem_pestat] mean and std.dev: (264.49, 138.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 943)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (395, 972, 2990)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8180)
[M::mem_pestat] mean and std.dev: (1453.39, 1503.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10775)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 370, 576)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1292)
[M::mem_pestat] mean and std.dev: (342.62, 200.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1650)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 705544 reads in 193.076 CPU sec, 6.152 real sec
[M::mem_process_seqs] Processed 704276 reads in 134.152 CPU sec, 4.223 real sec
[M::process] read 702164 sequences (100000081 bp) in 2.935 CPU sec, 3.080 real sec...
sorting block 70, #reads = 1075580 mem = 536881524 peak = 1065615360
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (110, 284345, 52, 122)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 339, 889)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2311)
[M::mem_pestat] mean and std.dev: (474.58, 428.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3022)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 238, 354)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 748)
[M::mem_pestat] mean and std.dev: (267.16, 139.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 945)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (651, 1144, 2794)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7080)
[M::mem_pestat] mean and std.dev: (1864.94, 1754.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9223)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 359, 1063)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2813)
[M::mem_pestat] mean and std.dev: (601.32, 645.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3688)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701674 sequences (100000012 bp) in 2.989 CPU sec, 3.103 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (95, 284085, 44, 93)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 318, 899)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2275)
[M::mem_pestat] mean and std.dev: (500.08, 502.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2963)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 240, 355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 749)
[M::mem_pestat] mean and std.dev: (267.76, 138.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 946)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (442, 808, 1945)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4951)
[M::mem_pestat] mean and std.dev: (1219.67, 1254.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6454)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 431, 876)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2196)
[M::mem_pestat] mean and std.dev: (433.46, 333.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2856)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702970 reads in 193.809 CPU sec, 6.152 real sec
sorting block 71, #reads = 1073605 mem = 536880450 peak = 1065615360
[M::mem_process_seqs] Processed 702164 reads in 132.494 CPU sec, 4.179 real sec
[M::process] read 701214 sequences (100000215 bp) in 3.032 CPU sec, 3.116 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (92, 283808, 41, 84)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 339, 743)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1869)
[M::mem_pestat] mean and std.dev: (424.48, 334.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2432)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 241, 357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 753)
[M::mem_pestat] mean and std.dev: (269.29, 140.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 951)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (508, 717, 1306)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2902)
[M::mem_pestat] mean and std.dev: (814.76, 548.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3700)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 297, 653)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1561)
[M::mem_pestat] mean and std.dev: (370.66, 305.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2015)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 72, #reads = 1073545 mem = 536881740 peak = 1065615360
[M::process] read 701852 sequences (100000298 bp) in 3.340 CPU sec, 3.530 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (114, 283568, 35, 119)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 340, 1133)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3041)
[M::mem_pestat] mean and std.dev: (640.12, 646.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3995)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 242, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 754)
[M::mem_pestat] mean and std.dev: (270.21, 140.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 952)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (287, 983, 2192)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6002)
[M::mem_pestat] mean and std.dev: (1222.58, 1106.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7907)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 296, 563)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1301)
[M::mem_pestat] mean and std.dev: (309.28, 181.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1670)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701674 reads in 191.335 CPU sec, 6.071 real sec
[M::mem_process_seqs] Processed 701214 reads in 130.408 CPU sec, 4.105 real sec
[M::process] read 700440 sequences (100000251 bp) in 3.193 CPU sec, 3.327 real sec...
sorting block 73, #reads = 1074955 mem = 536882541 peak = 1065615360
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (122, 284237, 40, 97)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 289, 540)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1298)
[M::mem_pestat] mean and std.dev: (314.71, 219.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1677)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 240, 356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 752)
[M::mem_pestat] mean and std.dev: (268.64, 139.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 950)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 975, 2949)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8483)
[M::mem_pestat] mean and std.dev: (1366.03, 1437.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11250)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 329, 848)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2094)
[M::mem_pestat] mean and std.dev: (444.00, 390.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2717)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700110 sequences (100000177 bp) in 3.258 CPU sec, 3.395 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (102, 283370, 38, 150)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 364, 706)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1720)
[M::mem_pestat] mean and std.dev: (420.20, 325.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2227)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 244, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 761)
[M::mem_pestat] mean and std.dev: (272.16, 141.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 961)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (305, 652, 1955)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5255)
[M::mem_pestat] mean and std.dev: (1181.00, 1207.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6905)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 256, 613)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1485)
[M::mem_pestat] mean and std.dev: (362.07, 284.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1921)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701852 reads in 189.258 CPU sec, 6.014 real sec
[M::mem_process_seqs] Processed 700440 reads in 130.259 CPU sec, 4.096 real sec
sorting block 74, #reads = 1074261 mem = 536878246 peak = 1065615360
[M::process] read 700978 sequences (100000239 bp) in 3.278 CPU sec, 3.424 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (86, 283721, 27, 116)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 333, 906)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2390)
[M::mem_pestat] mean and std.dev: (470.81, 465.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3132)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 246, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 765)
[M::mem_pestat] mean and std.dev: (273.54, 141.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 966)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 546, 1943)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5513)
[M::mem_pestat] mean and std.dev: (1128.00, 1324.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7298)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 306, 795)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1971)
[M::mem_pestat] mean and std.dev: (454.77, 410.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2559)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705272 sequences (100000168 bp) in 3.499 CPU sec, 3.674 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (91, 283417, 38, 109)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 300, 418)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 890)
[M::mem_pestat] mean and std.dev: (274.46, 124.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1126)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 243, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 760)
[M::mem_pestat] mean and std.dev: (271.84, 141.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 960)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 1120, 1693)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4707)
[M::mem_pestat] mean and std.dev: (1046.83, 1014.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6214)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 272, 533)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1229)
[M::mem_pestat] mean and std.dev: (359.72, 260.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1577)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700110 reads in 187.463 CPU sec, 5.965 real sec
sorting block 75, #reads = 1074120 mem = 536882616 peak = 1065615360
[M::mem_process_seqs] Processed 700978 reads in 129.817 CPU sec, 4.094 real sec
[M::process] read 711634 sequences (100000076 bp) in 3.581 CPU sec, 3.764 real sec...
sorting block 76, #reads = 1074707 mem = 536881135 peak = 1065615360
[M::process] read 710070 sequences (100000242 bp) in 3.145 CPU sec, 3.252 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 287305, 35, 105)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 361, 499)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1115)
[M::mem_pestat] mean and std.dev: (335.70, 200.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1423)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 216, 320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 670)
[M::mem_pestat] mean and std.dev: (243.19, 126.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 845)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (262, 692, 1572)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4192)
[M::mem_pestat] mean and std.dev: (1098.41, 1071.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5502)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 299, 1001)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2613)
[M::mem_pestat] mean and std.dev: (521.98, 556.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3419)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 711634 reads in 104.834 CPU sec, 3.295 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (100, 284629, 56, 115)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 299, 1044)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2776)
[M::mem_pestat] mean and std.dev: (524.80, 564.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3642)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 231, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 723)
[M::mem_pestat] mean and std.dev: (259.75, 136.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 913)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (325, 780, 2228)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6034)
[M::mem_pestat] mean and std.dev: (1244.20, 1271.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7937)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 291, 542)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1236)
[M::mem_pestat] mean and std.dev: (346.95, 221.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1583)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (81, 286826, 27, 88)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 356, 622)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1520)
[M::mem_pestat] mean and std.dev: (361.09, 275.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1969)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::process] read 708458 sequences (100000103 bp) in 3.311 CPU sec, 3.441 real sec...
[M::mem_pestat] (25, 50, 75) percentile: (147, 220, 327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 687)
[M::mem_pestat] mean and std.dev: (248.05, 129.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 867)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (314, 885, 1734)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4574)
[M::mem_pestat] mean and std.dev: (1261.31, 1374.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6760)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 234, 411)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 921)
[M::mem_pestat] mean and std.dev: (268.94, 186.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1176)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 705272 reads in 303.164 CPU sec, 9.603 real sec
sorting block 77, #reads = 1078531 mem = 536881247 peak = 1065615360
[M::mem_process_seqs] Processed 710070 reads in 153.255 CPU sec, 4.831 real sec
[M::process] read 707084 sequences (100000255 bp) in 3.486 CPU sec, 3.649 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (74, 286596, 33, 87)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 278, 446)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 982)
[M::mem_pestat] mean and std.dev: (278.32, 144.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1250)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 225, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 704)
[M::mem_pestat] mean and std.dev: (252.63, 131.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 889)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (849, 1619, 3221)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7965)
[M::mem_pestat] mean and std.dev: (1701.83, 1471.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10337)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 236, 845)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2201)
[M::mem_pestat] mean and std.dev: (482.28, 540.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2879)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 78, #reads = 1075809 mem = 536890176 peak = 1065615360
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (105, 285745, 47, 87)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 322, 602)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1448)
[M::mem_pestat] mean and std.dev: (394.44, 281.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1871)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 227, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 712)
[M::mem_pestat] mean and std.dev: (255.23, 132.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 899)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (223, 1060, 2642)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7480)
[M::mem_pestat] mean and std.dev: (1512.30, 1371.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9899)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 261, 476)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1058)
[M::mem_pestat] mean and std.dev: (257.23, 140.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1349)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705898 sequences (100000107 bp) in 3.033 CPU sec, 3.141 real sec...
[M::mem_process_seqs] Processed 708458 reads in 178.541 CPU sec, 5.680 real sec
[M::mem_process_seqs] Processed 707084 reads in 122.983 CPU sec, 3.884 real sec
sorting block 79, #reads = 1082409 mem = 536877596 peak = 1065615360
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (87, 285924, 41, 99)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 251, 665)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1633)
[M::mem_pestat] mean and std.dev: (351.00, 326.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2117)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 231, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 725)
[M::mem_pestat] mean and std.dev: (258.83, 134.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 916)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (276, 813, 4804)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13860)
[M::mem_pestat] mean and std.dev: (2669.05, 3220.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 18388)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (238, 313, 569)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1231)
[M::mem_pestat] mean and std.dev: (357.97, 241.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1562)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705356 sequences (100000111 bp) in 3.927 CPU sec, 4.211 real sec...
[M::mem_process_seqs] Processed 705898 reads in 102.401 CPU sec, 3.371 real sec
sorting block 80, #reads = 1080281 mem = 536877945 peak = 1065615360
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (109, 285744, 38, 98)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (141, 223, 399)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 915)
[M::mem_pestat] mean and std.dev: (254.90, 179.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1173)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 232, 346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 732)
[M::mem_pestat] mean and std.dev: (260.43, 135.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 925)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (368, 699, 1516)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3812)
[M::mem_pestat] mean and std.dev: (886.46, 795.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4960)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 274, 563)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1329)
[M::mem_pestat] mean and std.dev: (320.21, 239.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1712)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705438 sequences (100000229 bp) in 3.565 CPU sec, 3.793 real sec...
[M::mem_process_seqs] Processed 705356 reads in 116.215 CPU sec, 3.754 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (93, 285378, 43, 95)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 371, 1020)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2680)
[M::mem_pestat] mean and std.dev: (515.84, 500.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3510)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 232, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 726)
[M::mem_pestat] mean and std.dev: (259.69, 134.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 917)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (443, 818, 2718)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7268)
[M::mem_pestat] mean and std.dev: (1579.09, 1677.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9543)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 374, 520)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1214)
[M::mem_pestat] mean and std.dev: (336.57, 175.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1561)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705296 sequences (100000257 bp) in 3.362 CPU sec, 3.535 real sec...
[M::mem_process_seqs] Processed 705438 reads in 104.714 CPU sec, 3.360 real sec
sorting block 81, #reads = 1077836 mem = 536878365 peak = 1065615360
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (83, 285430, 42, 91)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 353, 644)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1510)
[M::mem_pestat] mean and std.dev: (411.84, 306.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1943)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 232, 345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 729)
[M::mem_pestat] mean and std.dev: (260.27, 134.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 921)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (262, 619, 1494)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3958)
[M::mem_pestat] mean and std.dev: (749.58, 666.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5190)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 237, 369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 781)
[M::mem_pestat] mean and std.dev: (252.16, 129.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 987)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 705296 reads in 104.707 CPU sec, 3.352 real sec
[M::process] read 704480 sequences (100000298 bp) in 3.461 CPU sec, 3.656 real sec...
sorting block 82, #reads = 1079078 mem = 536882465 peak = 1065615360
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (109, 284945, 43, 116)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 288, 574)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1354)
[M::mem_pestat] mean and std.dev: (295.04, 175.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1744)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 235, 348)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 736)
[M::mem_pestat] mean and std.dev: (262.24, 135.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 930)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (708, 1145, 2706)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6702)
[M::mem_pestat] mean and std.dev: (1979.07, 2026.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10084)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 292, 672)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1662)
[M::mem_pestat] mean and std.dev: (452.48, 432.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2184)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704480 reads in 105.274 CPU sec, 3.373 real sec
[M::process] read 705034 sequences (100000293 bp) in 3.224 CPU sec, 3.378 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (88, 285420, 52, 92)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 311, 533)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1191)
[M::mem_pestat] mean and std.dev: (341.94, 238.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1520)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 233, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 724)
[M::mem_pestat] mean and std.dev: (259.84, 133.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 914)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (536, 1113, 3152)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8384)
[M::mem_pestat] mean and std.dev: (1769.24, 1720.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11000)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 291, 920)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2336)
[M::mem_pestat] mean and std.dev: (448.87, 405.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3044)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704244 sequences (100000156 bp) in 2.895 CPU sec, 2.990 real sec...
[M::mem_process_seqs] Processed 705034 reads in 103.704 CPU sec, 3.326 real sec
sorting block 83, #reads = 1077983 mem = 536888301 peak = 1065615360
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (116, 284559, 44, 116)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 311, 989)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2601)
[M::mem_pestat] mean and std.dev: (499.38, 547.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3407)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 237, 352)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 746)
[M::mem_pestat] mean and std.dev: (265.02, 138.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 943)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (127, 605, 1609)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4573)
[M::mem_pestat] mean and std.dev: (757.40, 757.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6055)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 380, 753)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1809)
[M::mem_pestat] mean and std.dev: (431.70, 327.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2337)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702892 sequences (100000143 bp) in 3.348 CPU sec, 3.538 real sec...
[M::mem_process_seqs] Processed 704244 reads in 112.486 CPU sec, 3.601 real sec
sorting block 84, #reads = 1077316 mem = 536877666 peak = 1065615360
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (116, 284695, 34, 99)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 282, 914)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2350)
[M::mem_pestat] mean and std.dev: (446.94, 440.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3068)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 239, 355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 751)
[M::mem_pestat] mean and std.dev: (267.37, 138.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 949)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (325, 1108, 2221)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6013)
[M::mem_pestat] mean and std.dev: (1426.47, 1282.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7909)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 329, 725)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1819)
[M::mem_pestat] mean and std.dev: (426.08, 372.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2366)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701916 sequences (100000174 bp) in 3.356 CPU sec, 3.520 real sec...
[M::mem_process_seqs] Processed 702892 reads in 110.293 CPU sec, 3.532 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (139, 283814, 33, 124)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 315, 578)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1390)
[M::mem_pestat] mean and std.dev: (337.51, 244.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1796)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 241, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 758)
[M::mem_pestat] mean and std.dev: (269.66, 140.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 958)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (305, 1649, 2566)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7088)
[M::mem_pestat] mean and std.dev: (1428.87, 1346.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9349)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 357, 698)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1644)
[M::mem_pestat] mean and std.dev: (449.28, 362.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2117)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702524 sequences (100000200 bp) in 3.330 CPU sec, 3.512 real sec...
[M::mem_process_seqs] Processed 701916 reads in 109.904 CPU sec, 3.521 real sec
sorting block 85, #reads = 1075696 mem = 536879600 peak = 1065615360
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (102, 284260, 39, 121)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 367, 996)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2580)
[M::mem_pestat] mean and std.dev: (599.85, 612.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3372)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 237, 351)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 739)
[M::mem_pestat] mean and std.dev: (265.64, 137.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 933)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (537, 1186, 2582)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6672)
[M::mem_pestat] mean and std.dev: (1485.05, 1344.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8717)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 323, 760)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1830)
[M::mem_pestat] mean and std.dev: (437.90, 354.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2365)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701366 sequences (100000255 bp) in 3.361 CPU sec, 3.536 real sec...
[M::mem_process_seqs] Processed 702524 reads in 113.688 CPU sec, 3.629 real sec
sorting block 86, #reads = 1074053 mem = 536877251 peak = 1065615360
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (128, 283342, 57, 117)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 281, 605)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1497)
[M::mem_pestat] mean and std.dev: (339.74, 272.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1943)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 240, 354)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 744)
[M::mem_pestat] mean and std.dev: (267.84, 137.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 939)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (352, 589, 1682)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4342)
[M::mem_pestat] mean and std.dev: (810.53, 918.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5672)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 317, 794)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1952)
[M::mem_pestat] mean and std.dev: (425.16, 377.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2531)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701744 sequences (100000096 bp) in 3.365 CPU sec, 3.540 real sec...
[M::mem_process_seqs] Processed 701366 reads in 115.732 CPU sec, 3.707 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (91, 283861, 50, 119)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 291, 930)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2392)
[M::mem_pestat] mean and std.dev: (400.52, 322.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3123)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 241, 357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 755)
[M::mem_pestat] mean and std.dev: (269.38, 140.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 954)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (271, 605, 1816)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4906)
[M::mem_pestat] mean and std.dev: (1000.71, 1012.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6451)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 359, 848)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2176)
[M::mem_pestat] mean and std.dev: (499.59, 469.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2840)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701658 sequences (100000235 bp) in 3.301 CPU sec, 3.443 real sec...
[M::mem_process_seqs] Processed 701744 reads in 110.784 CPU sec, 3.535 real sec
sorting block 87, #reads = 1073074 mem = 536877658 peak = 1065615360
[M::process] read 701316 sequences (100000265 bp) in 3.253 CPU sec, 3.395 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (113, 283828, 29, 85)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 297, 460)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1050)
[M::mem_pestat] mean and std.dev: (298.77, 169.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1345)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 241, 357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 753)
[M::mem_pestat] mean and std.dev: (269.62, 139.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 951)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (678, 1044, 2197)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5235)
[M::mem_pestat] mean and std.dev: (1318.65, 1190.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6754)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 291, 569)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1319)
[M::mem_pestat] mean and std.dev: (357.92, 258.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1694)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706508 sequences (100000125 bp) in 2.250 CPU sec, 2.248 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (113, 283613, 42, 126)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 302, 1148)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3048)
[M::mem_pestat] mean and std.dev: (515.42, 551.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3998)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 240, 356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 750)
[M::mem_pestat] mean and std.dev: (268.67, 139.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 947)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (329, 878, 1938)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5156)
[M::mem_pestat] mean and std.dev: (1168.15, 1027.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6765)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 492, 1702)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4686)
[M::mem_pestat] mean and std.dev: (935.75, 1118.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6178)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701658 reads in 194.137 CPU sec, 6.094 real sec
[M::process] read 716160 sequences (100000078 bp) in 2.681 CPU sec, 2.791 real sec...
sorting block 88, #reads = 1071668 mem = 536883330 peak = 1065615360
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (80, 285100, 42, 106)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 382, 723)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1855)
[M::mem_pestat] mean and std.dev: (408.54, 352.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2421)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 228, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 713)
[M::mem_pestat] mean and std.dev: (256.41, 134.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 900)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (229, 560, 1647)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4483)
[M::mem_pestat] mean and std.dev: (806.66, 850.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5901)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 321, 496)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1090)
[M::mem_pestat] mean and std.dev: (301.86, 175.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1387)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 713570 sequences (100000171 bp) in 2.318 CPU sec, 2.324 real sec...
[M::mem_process_seqs] Processed 706508 reads in 128.284 CPU sec, 4.052 real sec
[M::mem_process_seqs] Processed 701316 reads in 278.108 CPU sec, 8.775 real sec
sorting block 89, #reads = 1067415 mem = 536882697 peak = 1065615360
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (80, 289182, 25, 82)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 284, 391)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 855)
[M::mem_pestat] mean and std.dev: (227.55, 98.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1087)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (140, 206, 302)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 626)
[M::mem_pestat] mean and std.dev: (231.65, 118.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 788)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (482, 1021, 2796)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7424)
[M::mem_pestat] mean and std.dev: (1759.80, 1580.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9738)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 311, 835)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2171)
[M::mem_pestat] mean and std.dev: (434.68, 354.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2839)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 711960 sequences (100000276 bp) in 3.013 CPU sec, 3.113 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (107, 288004, 36, 97)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 348, 1074)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2826)
[M::mem_pestat] mean and std.dev: (539.51, 550.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3702)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (143, 212, 314)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 656)
[M::mem_pestat] mean and std.dev: (239.27, 123.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 827)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (314, 1529, 2523)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6941)
[M::mem_pestat] mean and std.dev: (1558.79, 1501.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9150)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 331, 682)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1624)
[M::mem_pestat] mean and std.dev: (412.20, 317.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2095)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 709958 sequences (100000210 bp) in 2.316 CPU sec, 2.316 real sec...
[M::mem_process_seqs] Processed 716160 reads in 232.858 CPU sec, 7.357 real sec
[M::mem_process_seqs] Processed 713570 reads in 138.255 CPU sec, 4.362 real sec
sorting block 90, #reads = 1075726 mem = 536879232 peak = 1065615360
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (83, 287929, 47, 90)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 288, 1071)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2871)
[M::mem_pestat] mean and std.dev: (588.20, 712.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3771)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (144, 216, 320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 672)
[M::mem_pestat] mean and std.dev: (243.13, 125.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 848)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (417, 705, 1254)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2928)
[M::mem_pestat] mean and std.dev: (666.34, 469.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3765)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 331, 625)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1449)
[M::mem_pestat] mean and std.dev: (352.16, 242.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1861)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 708542 sequences (100000198 bp) in 2.980 CPU sec, 3.058 real sec...
[M::process] read 706902 sequences (100000137 bp) in 1.710 CPU sec, 1.718 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (109, 287482, 23, 86)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 301, 647)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1553)
[M::mem_pestat] mean and std.dev: (357.96, 305.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2006)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 220, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 690)
[M::mem_pestat] mean and std.dev: (248.45, 128.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 871)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (486, 725, 1619)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3885)
[M::mem_pestat] mean and std.dev: (922.50, 599.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5018)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 301, 618)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1410)
[M::mem_pestat] mean and std.dev: (372.83, 281.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1806)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 711960 reads in 204.655 CPU sec, 6.493 real sec
sorting block 91, #reads = 1076501 mem = 536883414 peak = 1065615360
[M::mem_process_seqs] Processed 709958 reads in 138.643 CPU sec, 4.420 real sec
sorting block 92, #reads = 1076202 mem = 536876753 peak = 1065615360
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (98, 286393, 45, 88)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 422, 1270)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3394)
[M::mem_pestat] mean and std.dev: (789.99, 844.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4456)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 224, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 707)
[M::mem_pestat] mean and std.dev: (252.59, 131.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 893)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (629, 1205, 1935)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4547)
[M::mem_pestat] mean and std.dev: (1256.83, 959.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5853)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 301, 885)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2259)
[M::mem_pestat] mean and std.dev: (475.71, 435.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2946)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 707290 sequences (100000152 bp) in 2.706 CPU sec, 2.854 real sec...
[M::process] read 706556 sequences (100000211 bp) in 1.930 CPU sec, 1.933 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (89, 286002, 48, 100)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 303, 680)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1726)
[M::mem_pestat] mean and std.dev: (376.70, 344.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2249)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 228, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 721)
[M::mem_pestat] mean and std.dev: (257.53, 134.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 911)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (67, 783, 2151)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6319)
[M::mem_pestat] mean and std.dev: (1231.33, 1347.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8403)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 320, 957)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2489)
[M::mem_pestat] mean and std.dev: (513.96, 520.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3255)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 708542 reads in 201.052 CPU sec, 6.375 real sec
[M::mem_process_seqs] Processed 706902 reads in 136.458 CPU sec, 4.335 real sec
sorting block 93, #reads = 1075198 mem = 536880414 peak = 1065615360
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (91, 285523, 37, 85)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 380, 494)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1088)
[M::mem_pestat] mean and std.dev: (366.52, 231.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1385)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 230, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 728)
[M::mem_pestat] mean and std.dev: (259.10, 135.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 920)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (111, 474, 1126)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3156)
[M::mem_pestat] mean and std.dev: (727.28, 813.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4171)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 299, 590)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1408)
[M::mem_pestat] mean and std.dev: (339.76, 217.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1817)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 707262 sequences (100000063 bp) in 3.057 CPU sec, 3.144 real sec...
[M::process] read 703974 sequences (100000120 bp) in 2.520 CPU sec, 2.524 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (118, 285950, 54, 96)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 380, 971)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2609)
[M::mem_pestat] mean and std.dev: (532.33, 544.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3428)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 226, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 712)
[M::mem_pestat] mean and std.dev: (255.53, 133.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 899)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 1027, 2152)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6042)
[M::mem_pestat] mean and std.dev: (1264.75, 1280.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7987)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 333, 773)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1907)
[M::mem_pestat] mean and std.dev: (487.10, 448.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2474)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 706556 reads in 204.310 CPU sec, 6.451 real sec
sorting block 94, #reads = 1074638 mem = 536885525 peak = 1065615360
[M::mem_process_seqs] Processed 707290 reads in 231.955 CPU sec, 7.355 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (114, 285780, 49, 105)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 349, 1389)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3807)
[M::mem_pestat] mean and std.dev: (621.68, 871.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5016)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 225, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 702)
[M::mem_pestat] mean and std.dev: (253.51, 131.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 886)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (656, 1913, 3879)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10325)
[M::mem_pestat] mean and std.dev: (2513.10, 2434.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13548)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 318, 557)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1257)
[M::mem_pestat] mean and std.dev: (309.87, 162.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1607)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702384 sequences (100000001 bp) in 3.341 CPU sec, 3.475 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (109, 284603, 49, 95)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 281, 636)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1530)
[M::mem_pestat] mean and std.dev: (386.51, 307.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1977)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 235, 347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 731)
[M::mem_pestat] mean and std.dev: (262.56, 135.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 923)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (465, 872, 1955)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4935)
[M::mem_pestat] mean and std.dev: (1074.48, 853.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6425)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 273, 498)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1112)
[M::mem_pestat] mean and std.dev: (301.80, 198.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1419)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701624 sequences (100000189 bp) in 2.540 CPU sec, 2.541 real sec...
[M::mem_process_seqs] Processed 707262 reads in 206.563 CPU sec, 6.515 real sec
sorting block 95, #reads = 1073571 mem = 536880908 peak = 1065615360
[M::mem_process_seqs] Processed 703974 reads in 234.156 CPU sec, 7.418 real sec
sorting block 96, #reads = 1073885 mem = 536880276 peak = 1065615360
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (116, 283664, 39, 128)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 276, 690)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1714)
[M::mem_pestat] mean and std.dev: (405.60, 385.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2226)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 240, 353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 743)
[M::mem_pestat] mean and std.dev: (266.77, 137.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 938)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (397, 818, 2254)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5968)
[M::mem_pestat] mean and std.dev: (1452.97, 1471.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7825)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 325, 1050)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2816)
[M::mem_pestat] mean and std.dev: (487.39, 501.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3699)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702098 sequences (100000128 bp) in 3.228 CPU sec, 3.299 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (113, 283010, 55, 132)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 294, 922)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2420)
[M::mem_pestat] mean and std.dev: (526.89, 593.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3169)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 240, 353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 741)
[M::mem_pestat] mean and std.dev: (266.67, 136.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 935)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (350, 939, 1514)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3842)
[M::mem_pestat] mean and std.dev: (971.20, 799.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5006)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 269, 724)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1828)
[M::mem_pestat] mean and std.dev: (401.16, 370.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2380)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701192 sequences (100000008 bp) in 2.550 CPU sec, 2.552 real sec...
[M::mem_process_seqs] Processed 702384 reads in 197.153 CPU sec, 6.220 real sec
[M::mem_process_seqs] Processed 701624 reads in 143.165 CPU sec, 4.540 real sec
sorting block 97, #reads = 1072063 mem = 536876255 peak = 1065615360
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (86, 283738, 36, 123)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 305, 623)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1481)
[M::mem_pestat] mean and std.dev: (341.38, 236.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1910)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 238, 348)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 728)
[M::mem_pestat] mean and std.dev: (264.13, 134.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 918)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (982, 1571, 2254)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4798)
[M::mem_pestat] mean and std.dev: (1484.88, 735.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6070)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 338, 644)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1568)
[M::mem_pestat] mean and std.dev: (362.13, 279.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2030)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700840 sequences (100000083 bp) in 2.905 CPU sec, 3.053 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (96, 283560, 49, 126)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 309, 519)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1133)
[M::mem_pestat] mean and std.dev: (298.82, 187.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1440)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 241, 351)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 733)
[M::mem_pestat] mean and std.dev: (266.47, 135.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 924)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (542, 1296, 3634)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9818)
[M::mem_pestat] mean and std.dev: (2025.98, 2167.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12910)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 346, 1103)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2871)
[M::mem_pestat] mean and std.dev: (564.77, 590.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3755)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700506 sequences (100000184 bp) in 2.350 CPU sec, 2.357 real sec...
[M::mem_process_seqs] Processed 702098 reads in 188.692 CPU sec, 5.962 real sec
[M::mem_process_seqs] Processed 701192 reads in 129.640 CPU sec, 4.091 real sec
sorting block 98, #reads = 1074942 mem = 536882299 peak = 1065615360
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (95, 283382, 47, 104)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 294, 1139)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3087)
[M::mem_pestat] mean and std.dev: (576.93, 637.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4061)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 241, 352)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 736)
[M::mem_pestat] mean and std.dev: (266.77, 135.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 928)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (241, 1167, 1653)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4477)
[M::mem_pestat] mean and std.dev: (1053.09, 889.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5889)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 326, 687)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1621)
[M::mem_pestat] mean and std.dev: (440.79, 373.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2088)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699958 sequences (100000129 bp) in 2.947 CPU sec, 3.092 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (89, 283074, 57, 100)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 267, 573)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1365)
[M::mem_pestat] mean and std.dev: (361.42, 266.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1761)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 245, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 758)
[M::mem_pestat] mean and std.dev: (271.95, 139.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 957)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (472, 1528, 3201)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8659)
[M::mem_pestat] mean and std.dev: (2206.02, 2151.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11388)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 272, 461)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1015)
[M::mem_pestat] mean and std.dev: (262.22, 130.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1292)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700336 sequences (100000251 bp) in 2.321 CPU sec, 2.329 real sec...
[M::mem_process_seqs] Processed 700840 reads in 187.019 CPU sec, 5.912 real sec
sorting block 99, #reads = 1074636 mem = 536876043 peak = 1065615360
[M::mem_process_seqs] Processed 700506 reads in 129.313 CPU sec, 4.078 real sec
[M::process] read 58066 sequences (8276060 bp) in 0.901 CPU sec, 0.913 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (81, 283732, 43, 102)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 323, 832)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2146)
[M::mem_pestat] mean and std.dev: (497.28, 469.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2803)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 247, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 762)
[M::mem_pestat] mean and std.dev: (273.30, 140.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 962)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (284, 684, 1542)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4058)
[M::mem_pestat] mean and std.dev: (765.36, 629.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5316)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 392, 891)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2267)
[M::mem_pestat] mean and std.dev: (456.85, 421.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2955)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (111, 283466, 51, 110)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 322, 673)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1621)
[M::mem_pestat] mean and std.dev: (404.37, 347.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2095)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 245, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 764)
[M::mem_pestat] mean and std.dev: (273.14, 141.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 965)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (336, 883, 2617)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7179)
[M::mem_pestat] mean and std.dev: (1206.76, 1240.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9460)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 334, 523)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1167)
[M::mem_pestat] mean and std.dev: (358.64, 239.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1489)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (6, 23383, 3, 9)
[M::mem_pestat] skip orientation FF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 238, 353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 743)
[M::mem_pestat] mean and std.dev: (265.81, 136.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 938)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] skip orientation RR as there are not enough pairs
[M::mem_process_seqs] Processed 699958 reads in 192.154 CPU sec, 6.210 real sec
sorting block 100, #reads = 1074251 mem = 536881782 peak = 1065615360
[M::mem_process_seqs] Processed 700336 reads in 137.906 CPU sec, 4.459 real sec
[M::mem_process_seqs] Processed 58066 reads in 140.599 CPU sec, 4.554 real sec
sorting block 101, #reads = 1075854 mem = 536887032 peak = 1085595648
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000c06f2
  features: bfebfbff 7ffefbff
  extended: f3bfb7ef fb417ffe
  amd bits: 2c100800 00000121
     brand: INTEL(R) XEON(R) PLATINUM 8559C
threads: 31
algo: bwa-mem
license: sentieon:klib=31
reads: 109053494
overall: 70008815616 mem 18292.040 user 561.176 sys 628.583 real
[main] Version: 0.7.17-r1188
[main] CMD: /opt/conda/share/sentieon-202308.03-3/libexec/bwa mem -K 100000000 -Y -R @RG\tID:A23MHWWLT4.1136_85O-T1-TDNA-1_A23MHWWLT4_1.L004\tPU:L004\tSM:1136_85O-T1-TDNA-1_A23MHWWLT4_1\tLB:1136_85O-T1-TDNA-1_A23MHWWLT4_1\tDS:s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta\tPL:ILLUMINA -t 31 ./BWAIndex/Homo_sapiens_assembly38.fasta.64 1136_85O-T1-TDNA-1_A23MHWWLT4_1_R1.fastq.gz 1136_85O-T1-TDNA-1_A23MHWWLT4_1_R2.fastq.gz
[main] Real time: 628.621 sec; CPU: 18853.220 sec
sorting block 102, #reads = 396537 mem = 198967715 peak = 1085595648
uniq header count 1
merging 103 blocks
sw version: sentieon-genomics-202308.03
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000c06f2
  features: bfebfbff 7ffefbff
  extended: f3bfb7ef fb417ffe
  amd bits: 2c100800 00000121
     brand: INTEL(R) XEON(R) PLATINUM 8559C
threads: 31 max 192
algo: util-sort
license: sentieon:util=1
output file size: 6274341682
output reads: 110221104
bam_mem_sort: 103 calls 55.064 user 1.278 sys 56.557 real
bam_write: 103 calls 30.911 user 1.532 sys 33.017 real
execute: 1 calls 34.903 user 1.713 sys 675.422 real
merge_files: 1 calls 34.855 user 1.702 sys 46.524 real
parse_chunk: 1638 calls 88.920 user 21.715 sys 112.483 real
read_chunk: 4433 calls 51.797 user 33.894 sys 575.020 real
sort_block: 1 calls 34.428 user 33.041 sys 552.017 real
write_chunk: 2793 calls 34.408 user 1.418 sys 45.525 real
overall: 3355336704 mem 1799.662 user 90.417 sys 675.447 real
ls: cannot access '*.cram': No such file or directory