This software is licensed to bgold@natera.com by Sentieon Inc.
cmdline: /opt/conda/share/sentieon-202308.03-3/libexec/util sort -r Homo_sapiens_assembly38.fasta -t 31 -o 1136_85O-T1-TDNA-1_A23MHWWLT4_1.bam --sam2bam -
This software is licensed to bgold@natera.com by Sentieon Inc.
version: sentieon-genomics-202308.03
[M::bwa_idx_load_from_disk] read 3171 ALT contigs
[M::main_mem] bwa index loaded in 2163.783 CPU sec, 74.295 real sec
[M::process] read 704722 sequences (100000128 bp) in 1.036 CPU sec, 1.038 real sec...
[M::process] read 704862 sequences (100000154 bp) in 1.670 CPU sec, 1.695 real sec...
[M::process] read 704432 sequences (100000140 bp) in 1.712 CPU sec, 1.754 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (83, 284644, 35, 124)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 249, 825)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2133)
[M::mem_pestat] mean and std.dev: (423.74, 451.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2787)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 233, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 721)
[M::mem_pestat] mean and std.dev: (259.57, 133.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 910)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (444, 655, 1517)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3663)
[M::mem_pestat] mean and std.dev: (890.19, 838.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4736)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 308, 707)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1733)
[M::mem_pestat] mean and std.dev: (396.18, 361.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2246)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704044 sequences (100000288 bp) in 1.766 CPU sec, 1.821 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (100, 285104, 49, 86)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 271, 687)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1733)
[M::mem_pestat] mean and std.dev: (334.51, 300.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2256)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 235, 345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 725)
[M::mem_pestat] mean and std.dev: (261.15, 134.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 915)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (641, 911, 2567)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6419)
[M::mem_pestat] mean and std.dev: (1393.96, 1239.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8345)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 296, 959)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2527)
[M::mem_pestat] mean and std.dev: (536.72, 533.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3311)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (98, 284731, 53, 115)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 251, 550)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1338)
[M::mem_pestat] mean and std.dev: (306.74, 229.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1732)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 233, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 721)
[M::mem_pestat] mean and std.dev: (259.49, 133.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 910)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (513, 838, 3263)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8763)
[M::mem_pestat] mean and std.dev: (1987.34, 2399.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11587)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 304, 891)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2273)
[M::mem_pestat] mean and std.dev: (505.27, 509.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2964)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704722 reads in 296.982 CPU sec, 9.547 real sec
[M::mem_process_seqs] Processed 704432 reads in 201.976 CPU sec, 6.517 real sec
[M::mem_process_seqs] Processed 704862 reads in 222.263 CPU sec, 7.226 real sec
sorting block 0, #reads = 1079812 mem = 536877979 peak = 593317888
[M::process] read 704074 sequences (100000053 bp) in 2.721 CPU sec, 2.901 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (111, 284682, 45, 105)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 329, 628)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1466)
[M::mem_pestat] mean and std.dev: (381.65, 284.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1885)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 236, 348)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 734)
[M::mem_pestat] mean and std.dev: (262.70, 135.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 927)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (238, 956, 4905)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 14239)
[M::mem_pestat] mean and std.dev: (2233.38, 2648.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 18906)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 264, 405)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 833)
[M::mem_pestat] mean and std.dev: (268.36, 131.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1047)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704044 reads in 104.396 CPU sec, 3.683 real sec
sorting block 1, #reads = 1080113 mem = 536884140 peak = 851267584
[M::process] read 703780 sequences (100000295 bp) in 1.788 CPU sec, 1.887 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (125, 284814, 40, 117)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 297, 476)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1086)
[M::mem_pestat] mean and std.dev: (290.72, 175.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1391)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 236, 350)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 738)
[M::mem_pestat] mean and std.dev: (263.73, 137.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 932)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (244, 618, 1233)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3211)
[M::mem_pestat] mean and std.dev: (697.91, 709.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4200)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 424, 751)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1833)
[M::mem_pestat] mean and std.dev: (511.26, 358.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2374)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701730 sequences (100000071 bp) in 1.626 CPU sec, 1.644 real sec...
[M::process] read 700538 sequences (100000163 bp) in 1.246 CPU sec, 1.251 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (117, 284593, 38, 108)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 296, 628)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1524)
[M::mem_pestat] mean and std.dev: (364.23, 247.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1972)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 236, 350)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 738)
[M::mem_pestat] mean and std.dev: (263.61, 136.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 932)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (482, 1068, 1485)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3491)
[M::mem_pestat] mean and std.dev: (915.72, 671.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4494)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 307, 613)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1461)
[M::mem_pestat] mean and std.dev: (339.96, 264.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1885)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704074 reads in 201.829 CPU sec, 6.470 real sec
[M::mem_process_seqs] Processed 703780 reads in 118.077 CPU sec, 3.777 real sec
sorting block 2, #reads = 1080315 mem = 536878789 peak = 851267584
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (88, 284300, 43, 124)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 306, 1138)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3040)
[M::mem_pestat] mean and std.dev: (592.83, 703.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3991)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 244, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 765)
[M::mem_pestat] mean and std.dev: (271.21, 140.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 967)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (486, 1170, 2642)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6954)
[M::mem_pestat] mean and std.dev: (1567.83, 1358.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9110)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 339, 1076)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2816)
[M::mem_pestat] mean and std.dev: (589.31, 616.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3686)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700366 sequences (100000239 bp) in 2.657 CPU sec, 2.808 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (101, 283357, 37, 92)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 332, 1029)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2783)
[M::mem_pestat] mean and std.dev: (504.02, 609.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3660)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 248, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 779)
[M::mem_pestat] mean and std.dev: (275.31, 143.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 985)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (248, 735, 2810)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7934)
[M::mem_pestat] mean and std.dev: (1547.86, 1582.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10496)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 279, 543)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1239)
[M::mem_pestat] mean and std.dev: (318.55, 201.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1587)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700012 sequences (100000100 bp) in 1.984 CPU sec, 1.989 real sec...
[M::mem_process_seqs] Processed 701730 reads in 179.154 CPU sec, 5.700 real sec
sorting block 3, #reads = 1078361 mem = 536879328 peak = 851267584
[M::mem_process_seqs] Processed 700538 reads in 121.994 CPU sec, 4.072 real sec
sorting block 4, #reads = 1078596 mem = 536880418 peak = 886116352
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (103, 282747, 50, 114)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 224, 755)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1949)
[M::mem_pestat] mean and std.dev: (409.38, 473.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2546)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 248, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 773)
[M::mem_pestat] mean and std.dev: (274.32, 141.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 977)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (543, 2135, 5012)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13950)
[M::mem_pestat] mean and std.dev: (2748.62, 2637.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 18419)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (239, 332, 830)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2012)
[M::mem_pestat] mean and std.dev: (503.27, 426.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2603)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699510 sequences (100000146 bp) in 2.474 CPU sec, 2.587 real sec...
[M::process] read 698280 sequences (100000101 bp) in 1.860 CPU sec, 1.886 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (119, 283285, 42, 88)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (225, 310, 462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 936)
[M::mem_pestat] mean and std.dev: (310.83, 160.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1173)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 248, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 771)
[M::mem_pestat] mean and std.dev: (274.51, 141.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 974)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (130, 771, 2086)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5998)
[M::mem_pestat] mean and std.dev: (1190.98, 1274.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7954)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 337, 842)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2124)
[M::mem_pestat] mean and std.dev: (480.84, 407.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2765)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700366 reads in 181.301 CPU sec, 5.963 real sec
[M::mem_process_seqs] Processed 700012 reads in 121.221 CPU sec, 3.873 real sec
sorting block 5, #reads = 1076169 mem = 536879194 peak = 886116352
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (109, 282940, 34, 107)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 340, 681)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1601)
[M::mem_pestat] mean and std.dev: (392.38, 301.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2061)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 248, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 763)
[M::mem_pestat] mean and std.dev: (273.92, 140.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 963)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (438, 964, 1288)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2988)
[M::mem_pestat] mean and std.dev: (842.44, 562.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3838)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 342, 747)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1827)
[M::mem_pestat] mean and std.dev: (435.09, 381.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2367)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697896 sequences (100000254 bp) in 2.701 CPU sec, 2.916 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (131, 282425, 46, 123)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 285, 995)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2613)
[M::mem_pestat] mean and std.dev: (539.64, 562.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3422)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 253, 370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 780)
[M::mem_pestat] mean and std.dev: (278.66, 142.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 985)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (112, 513, 1292)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3652)
[M::mem_pestat] mean and std.dev: (713.37, 808.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4832)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 397, 1595)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4329)
[M::mem_pestat] mean and std.dev: (898.81, 1128.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5696)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697004 sequences (100000054 bp) in 2.055 CPU sec, 2.059 real sec...
[M::mem_process_seqs] Processed 699510 reads in 187.020 CPU sec, 5.982 real sec
sorting block 6, #reads = 1076541 mem = 536876940 peak = 886116352
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (138, 282188, 46, 106)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 272, 780)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2036)
[M::mem_pestat] mean and std.dev: (422.26, 400.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2664)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 255, 372)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 784)
[M::mem_pestat] mean and std.dev: (280.61, 143.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 990)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (367, 1453, 3500)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9766)
[M::mem_pestat] mean and std.dev: (2156.80, 2225.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12899)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 387, 831)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2065)
[M::mem_pestat] mean and std.dev: (514.70, 395.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2682)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697794 sequences (100000284 bp) in 2.245 CPU sec, 2.253 real sec...
[M::mem_process_seqs] Processed 697896 reads in 110.188 CPU sec, 3.719 real sec
[M::mem_process_seqs] Processed 698280 reads in 282.571 CPU sec, 9.232 real sec
sorting block 7, #reads = 1076479 mem = 536879235 peak = 886116352
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (135, 282085, 50, 115)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 377, 952)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2440)
[M::mem_pestat] mean and std.dev: (522.30, 530.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3184)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 255, 370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 776)
[M::mem_pestat] mean and std.dev: (279.79, 141.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 979)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (396, 889, 1985)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5163)
[M::mem_pestat] mean and std.dev: (1171.40, 1116.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6752)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 331, 962)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2504)
[M::mem_pestat] mean and std.dev: (527.04, 509.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3275)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697734 sequences (100000108 bp) in 2.576 CPU sec, 2.990 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (112, 281976, 50, 106)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 314, 839)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2177)
[M::mem_pestat] mean and std.dev: (461.85, 444.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2846)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 253, 369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 775)
[M::mem_pestat] mean and std.dev: (278.45, 141.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 978)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (289, 537, 3015)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8467)
[M::mem_pestat] mean and std.dev: (1199.04, 1499.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11193)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 306, 527)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1199)
[M::mem_pestat] mean and std.dev: (351.56, 223.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1535)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697004 reads in 210.974 CPU sec, 6.730 real sec
[M::mem_process_seqs] Processed 697794 reads in 128.323 CPU sec, 4.065 real sec
[M::process] read 698266 sequences (100000047 bp) in 2.295 CPU sec, 2.393 real sec...
sorting block 8, #reads = 1074138 mem = 536879385 peak = 886116352
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (120, 282400, 46, 122)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 312, 528)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1198)
[M::mem_pestat] mean and std.dev: (309.71, 197.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1533)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 252, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 766)
[M::mem_pestat] mean and std.dev: (276.78, 139.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 966)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (304, 1087, 2061)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5575)
[M::mem_pestat] mean and std.dev: (986.95, 783.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7332)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 330, 802)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2010)
[M::mem_pestat] mean and std.dev: (443.39, 388.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2614)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697350 sequences (100000202 bp) in 3.098 CPU sec, 3.453 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (120, 282331, 60, 122)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 337, 1175)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3099)
[M::mem_pestat] mean and std.dev: (548.84, 597.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4061)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 251, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 765)
[M::mem_pestat] mean and std.dev: (275.69, 139.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 965)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 311, 855)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2187)
[M::mem_pestat] mean and std.dev: (422.91, 409.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2853)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 360, 796)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1984)
[M::mem_pestat] mean and std.dev: (479.56, 412.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2578)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697734 reads in 193.022 CPU sec, 6.203 real sec
[M::process] read 697288 sequences (100000198 bp) in 2.197 CPU sec, 2.299 real sec...
[M::mem_process_seqs] Processed 698266 reads in 132.016 CPU sec, 4.249 real sec
sorting block 9, #reads = 1075751 mem = 536882099 peak = 886116352
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (136, 282466, 39, 102)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 317, 693)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1741)
[M::mem_pestat] mean and std.dev: (405.93, 358.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2265)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 255, 369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 773)
[M::mem_pestat] mean and std.dev: (278.99, 140.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 975)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (368, 611, 2252)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6020)
[M::mem_pestat] mean and std.dev: (1207.00, 1208.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7904)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 394, 526)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1090)
[M::mem_pestat] mean and std.dev: (393.33, 207.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1372)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 10, #reads = 1075503 mem = 536880571 peak = 886116352
[M::process] read 696908 sequences (100000093 bp) in 2.974 CPU sec, 3.400 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (113, 282258, 38, 107)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 311, 575)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1327)
[M::mem_pestat] mean and std.dev: (322.43, 224.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1703)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 255, 369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 773)
[M::mem_pestat] mean and std.dev: (278.73, 140.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 975)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 579, 1340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3706)
[M::mem_pestat] mean and std.dev: (949.68, 994.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4929)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 267, 553)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1255)
[M::mem_pestat] mean and std.dev: (305.84, 179.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1606)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697350 reads in 192.407 CPU sec, 6.411 real sec
[M::mem_process_seqs] Processed 697288 reads in 129.724 CPU sec, 4.145 real sec
[M::process] read 704302 sequences (100000029 bp) in 2.643 CPU sec, 2.893 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (112, 282111, 34, 110)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 308, 548)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1278)
[M::mem_pestat] mean and std.dev: (361.16, 251.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1643)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 257, 373)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 783)
[M::mem_pestat] mean and std.dev: (281.49, 142.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 988)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 762, 4176)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12222)
[M::mem_pestat] mean and std.dev: (2103.68, 2638.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 16245)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (231, 364, 927)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2319)
[M::mem_pestat] mean and std.dev: (483.31, 418.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3015)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 11, #reads = 1076093 mem = 536877793 peak = 886116352
[M::process] read 704802 sequences (100000140 bp) in 3.187 CPU sec, 3.598 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (101, 284699, 33, 102)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 267, 528)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1216)
[M::mem_pestat] mean and std.dev: (290.93, 184.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1560)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 235, 348)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 734)
[M::mem_pestat] mean and std.dev: (262.35, 135.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 927)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (139, 643, 1377)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3853)
[M::mem_pestat] mean and std.dev: (831.94, 891.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5091)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 292, 433)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 931)
[M::mem_pestat] mean and std.dev: (259.89, 124.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1180)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696908 reads in 197.050 CPU sec, 6.362 real sec
[M::mem_process_seqs] Processed 704302 reads in 132.432 CPU sec, 4.224 real sec
[M::process] read 704366 sequences (100000052 bp) in 2.533 CPU sec, 2.763 real sec...
sorting block 12, #reads = 1075448 mem = 536877791 peak = 886116352
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (103, 285060, 23, 117)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 280, 593)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1483)
[M::mem_pestat] mean and std.dev: (331.77, 256.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1928)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 234, 347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 733)
[M::mem_pestat] mean and std.dev: (261.73, 135.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 926)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (266, 733, 1271)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3281)
[M::mem_pestat] mean and std.dev: (697.33, 666.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4286)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 269, 939)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2457)
[M::mem_pestat] mean and std.dev: (493.17, 526.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3216)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703848 sequences (100000100 bp) in 2.985 CPU sec, 3.297 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (89, 284457, 28, 148)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 395, 982)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2542)
[M::mem_pestat] mean and std.dev: (534.99, 554.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3322)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 235, 347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 731)
[M::mem_pestat] mean and std.dev: (261.95, 135.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 923)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (534, 1504, 3447)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9273)
[M::mem_pestat] mean and std.dev: (1754.57, 1579.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12186)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 292, 496)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1082)
[M::mem_pestat] mean and std.dev: (296.93, 159.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1375)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704802 reads in 190.045 CPU sec, 6.108 real sec
[M::mem_process_seqs] Processed 704366 reads in 128.087 CPU sec, 4.072 real sec
sorting block 13, #reads = 1079274 mem = 536884649 peak = 886116352
[M::process] read 702918 sequences (100000225 bp) in 2.394 CPU sec, 2.526 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (123, 284182, 42, 109)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 258, 457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1047)
[M::mem_pestat] mean and std.dev: (282.39, 181.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1342)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 236, 351)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 743)
[M::mem_pestat] mean and std.dev: (264.59, 137.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 939)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (492, 687, 1303)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2925)
[M::mem_pestat] mean and std.dev: (797.66, 575.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3736)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 344, 840)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2086)
[M::mem_pestat] mean and std.dev: (408.95, 358.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2709)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 14, #reads = 1081300 mem = 536880597 peak = 886116352
[M::process] read 702754 sequences (100000132 bp) in 3.339 CPU sec, 3.632 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (103, 284164, 51, 108)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 298, 502)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1144)
[M::mem_pestat] mean and std.dev: (324.72, 197.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1465)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 239, 354)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 748)
[M::mem_pestat] mean and std.dev: (266.67, 137.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 945)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (396, 802, 2334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6210)
[M::mem_pestat] mean and std.dev: (1183.30, 1177.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8148)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 327, 581)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1371)
[M::mem_pestat] mean and std.dev: (373.44, 268.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1766)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703848 reads in 189.599 CPU sec, 6.086 real sec
[M::process] read 701198 sequences (100000268 bp) in 2.524 CPU sec, 2.688 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (85, 284018, 33, 83)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 299, 1035)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2723)
[M::mem_pestat] mean and std.dev: (518.04, 606.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3567)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 241, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 758)
[M::mem_pestat] mean and std.dev: (269.03, 140.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 958)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (276, 574, 1575)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4173)
[M::mem_pestat] mean and std.dev: (715.34, 703.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5472)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 291, 1028)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2724)
[M::mem_pestat] mean and std.dev: (507.99, 497.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3572)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702754 reads in 112.192 CPU sec, 3.567 real sec
[M::process] read 700724 sequences (100000054 bp) in 2.389 CPU sec, 2.418 real sec...
sorting block 15, #reads = 1079258 mem = 536878557 peak = 886116352
[M::mem_process_seqs] Processed 702918 reads in 293.903 CPU sec, 9.375 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (81, 283749, 31, 119)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 280, 628)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1566)
[M::mem_pestat] mean and std.dev: (317.46, 258.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2035)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 245, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 772)
[M::mem_pestat] mean and std.dev: (273.64, 142.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 976)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (370, 670, 2766)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7558)
[M::mem_pestat] mean and std.dev: (1608.31, 1920.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9954)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 312, 793)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1959)
[M::mem_pestat] mean and std.dev: (483.48, 413.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2542)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 16, #reads = 1079582 mem = 536880349 peak = 886116352
[M::process] read 700106 sequences (100000124 bp) in 3.099 CPU sec, 3.392 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (112, 283818, 44, 85)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 244, 552)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1310)
[M::mem_pestat] mean and std.dev: (318.32, 247.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1689)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 248, 369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 785)
[M::mem_pestat] mean and std.dev: (276.17, 144.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 993)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (362, 843, 1762)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4562)
[M::mem_pestat] mean and std.dev: (1064.79, 1093.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5962)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 314, 608)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1376)
[M::mem_pestat] mean and std.dev: (386.86, 273.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1760)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701198 reads in 210.679 CPU sec, 6.725 real sec
[M::mem_process_seqs] Processed 700724 reads in 129.220 CPU sec, 4.111 real sec
[M::process] read 699520 sequences (100000131 bp) in 2.886 CPU sec, 3.164 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (112, 283645, 44, 96)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 313, 668)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1636)
[M::mem_pestat] mean and std.dev: (340.48, 234.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2120)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 249, 369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 783)
[M::mem_pestat] mean and std.dev: (276.95, 143.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 990)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (259, 548, 1014)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2524)
[M::mem_pestat] mean and std.dev: (560.64, 446.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3279)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 315, 559)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1297)
[M::mem_pestat] mean and std.dev: (344.92, 227.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1666)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 17, #reads = 1078603 mem = 536879628 peak = 886116352
[M::process] read 699118 sequences (100000047 bp) in 2.940 CPU sec, 3.275 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (98, 283046, 64, 112)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 276, 498)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1148)
[M::mem_pestat] mean and std.dev: (320.38, 215.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1473)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 251, 371)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 787)
[M::mem_pestat] mean and std.dev: (278.17, 143.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 995)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (243, 810, 1359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3591)
[M::mem_pestat] mean and std.dev: (819.91, 686.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4707)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 290, 698)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1720)
[M::mem_pestat] mean and std.dev: (340.56, 262.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2231)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700106 reads in 194.762 CPU sec, 6.277 real sec
[M::mem_process_seqs] Processed 699520 reads in 128.411 CPU sec, 4.101 real sec
[M::process] read 698024 sequences (100000197 bp) in 2.826 CPU sec, 3.096 real sec...
sorting block 18, #reads = 1078466 mem = 536879096 peak = 886116352
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (102, 282920, 41, 137)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 268, 516)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1254)
[M::mem_pestat] mean and std.dev: (287.01, 191.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1623)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 251, 369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 779)
[M::mem_pestat] mean and std.dev: (277.24, 142.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 984)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (263, 639, 3161)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8957)
[M::mem_pestat] mean and std.dev: (1828.90, 2052.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11855)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (236, 343, 503)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1037)
[M::mem_pestat] mean and std.dev: (353.70, 192.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1304)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698056 sequences (100000219 bp) in 2.921 CPU sec, 3.224 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (133, 282412, 49, 124)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 304, 861)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2221)
[M::mem_pestat] mean and std.dev: (461.68, 376.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2901)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 255, 373)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 787)
[M::mem_pestat] mean and std.dev: (280.74, 143.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 994)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (391, 1065, 2124)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5590)
[M::mem_pestat] mean and std.dev: (1333.46, 1415.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7323)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (226, 323, 565)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1243)
[M::mem_pestat] mean and std.dev: (326.00, 199.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1582)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699118 reads in 195.638 CPU sec, 6.294 real sec
[M::mem_process_seqs] Processed 698024 reads in 132.400 CPU sec, 4.213 real sec
sorting block 19, #reads = 1077529 mem = 536879532 peak = 886116352
[M::process] read 697550 sequences (100000229 bp) in 2.628 CPU sec, 2.782 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (93, 282817, 36, 116)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 284, 470)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1060)
[M::mem_pestat] mean and std.dev: (287.99, 177.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1355)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 254, 371)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 781)
[M::mem_pestat] mean and std.dev: (279.38, 142.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 986)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (292, 785, 2724)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7588)
[M::mem_pestat] mean and std.dev: (1273.83, 1064.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10020)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (250, 459, 823)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1969)
[M::mem_pestat] mean and std.dev: (479.06, 312.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2542)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697274 sequences (100000154 bp) in 2.763 CPU sec, 3.085 real sec...
sorting block 20, #reads = 1075804 mem = 536880216 peak = 886116352
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (128, 282641, 40, 117)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 305, 731)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1787)
[M::mem_pestat] mean and std.dev: (402.10, 358.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2315)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 256, 372)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 782)
[M::mem_pestat] mean and std.dev: (280.61, 142.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 987)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 919, 2436)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6896)
[M::mem_pestat] mean and std.dev: (1125.38, 1223.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9126)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 368, 788)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1906)
[M::mem_pestat] mean and std.dev: (473.68, 384.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2465)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698056 reads in 189.577 CPU sec, 6.091 real sec
[M::process] read 697780 sequences (100000293 bp) in 2.139 CPU sec, 2.215 real sec...
[M::mem_process_seqs] Processed 697550 reads in 128.467 CPU sec, 4.246 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (123, 282923, 55, 114)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 287, 575)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1357)
[M::mem_pestat] mean and std.dev: (332.55, 241.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1748)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 254, 369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 773)
[M::mem_pestat] mean and std.dev: (278.66, 140.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 975)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 498, 1285)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3441)
[M::mem_pestat] mean and std.dev: (818.75, 855.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4519)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 302, 569)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1341)
[M::mem_pestat] mean and std.dev: (308.36, 203.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1727)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 21, #reads = 1076124 mem = 536878394 peak = 886116352
[M::process] read 697784 sequences (100000011 bp) in 2.614 CPU sec, 2.870 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (106, 282315, 28, 113)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 363, 1311)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3571)
[M::mem_pestat] mean and std.dev: (653.45, 763.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4701)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 253, 368)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 772)
[M::mem_pestat] mean and std.dev: (277.59, 140.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 974)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (340, 763, 1690)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4390)
[M::mem_pestat] mean and std.dev: (1005.30, 841.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5740)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 343, 1005)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2585)
[M::mem_pestat] mean and std.dev: (512.47, 463.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3375)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697274 reads in 193.256 CPU sec, 6.376 real sec
[M::process] read 697796 sequences (100000060 bp) in 1.825 CPU sec, 1.918 real sec...
[M::mem_process_seqs] Processed 697780 reads in 129.397 CPU sec, 4.131 real sec
sorting block 22, #reads = 1076122 mem = 536878316 peak = 886116352
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (113, 282281, 64, 122)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 295, 466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1040)
[M::mem_pestat] mean and std.dev: (332.03, 223.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1327)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 253, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 766)
[M::mem_pestat] mean and std.dev: (277.05, 140.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 966)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (491, 1006, 3198)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8612)
[M::mem_pestat] mean and std.dev: (1930.42, 2148.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11319)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 403, 897)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2293)
[M::mem_pestat] mean and std.dev: (503.15, 498.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2991)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697778 sequences (100000149 bp) in 2.770 CPU sec, 3.019 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (89, 282412, 45, 133)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 399, 1884)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5228)
[M::mem_pestat] mean and std.dev: (812.31, 994.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6900)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 253, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 769)
[M::mem_pestat] mean and std.dev: (277.34, 139.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 970)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 483, 1366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3770)
[M::mem_pestat] mean and std.dev: (733.38, 830.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4972)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 375, 758)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1818)
[M::mem_pestat] mean and std.dev: (458.34, 349.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2348)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697770 sequences (100000100 bp) in 1.881 CPU sec, 1.889 real sec...
[M::mem_process_seqs] Processed 697784 reads in 201.454 CPU sec, 6.474 real sec
[M::mem_process_seqs] Processed 697796 reads in 132.515 CPU sec, 4.222 real sec
sorting block 23, #reads = 1075713 mem = 536877833 peak = 886116352
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (117, 282396, 60, 151)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 314, 573)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1351)
[M::mem_pestat] mean and std.dev: (365.38, 266.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1740)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 252, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 766)
[M::mem_pestat] mean and std.dev: (276.37, 139.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 966)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (606, 1040, 2598)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6582)
[M::mem_pestat] mean and std.dev: (1561.71, 1445.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8574)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (237, 379, 1330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3516)
[M::mem_pestat] mean and std.dev: (761.11, 761.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4609)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703328 sequences (100000179 bp) in 2.945 CPU sec, 3.284 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (104, 282037, 62, 100)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 237, 531)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1285)
[M::mem_pestat] mean and std.dev: (313.74, 254.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1662)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 254, 370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 778)
[M::mem_pestat] mean and std.dev: (279.41, 142.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 982)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (430, 1424, 4457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12511)
[M::mem_pestat] mean and std.dev: (2814.89, 3059.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 16538)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 425, 1231)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3259)
[M::mem_pestat] mean and std.dev: (626.44, 566.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4273)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697778 reads in 195.768 CPU sec, 6.289 real sec
sorting block 24, #reads = 1074864 mem = 536877593 peak = 886116352
[M::process] read 704962 sequences (100000293 bp) in 2.002 CPU sec, 2.080 real sec...
[M::mem_process_seqs] Processed 697770 reads in 131.920 CPU sec, 4.205 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (99, 284479, 37, 100)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 278, 692)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1676)
[M::mem_pestat] mean and std.dev: (390.40, 349.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2168)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 237, 351)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 741)
[M::mem_pestat] mean and std.dev: (264.71, 137.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 936)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 1205, 2274)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6504)
[M::mem_pestat] mean and std.dev: (1717.83, 1923.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9410)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 371, 747)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1803)
[M::mem_pestat] mean and std.dev: (455.76, 363.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2331)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 25, #reads = 1075589 mem = 536879158 peak = 886116352
[M::process] read 704034 sequences (100000100 bp) in 3.107 CPU sec, 3.437 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (122, 285112, 46, 81)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 358, 1440)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3920)
[M::mem_pestat] mean and std.dev: (588.10, 833.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5160)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 233, 346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 730)
[M::mem_pestat] mean and std.dev: (260.82, 135.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 922)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (513, 875, 1412)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3210)
[M::mem_pestat] mean and std.dev: (1022.16, 801.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4228)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 278, 674)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1670)
[M::mem_pestat] mean and std.dev: (347.19, 300.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2168)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703328 reads in 193.699 CPU sec, 6.236 real sec
[M::mem_process_seqs] Processed 704962 reads in 130.199 CPU sec, 4.142 real sec
[M::process] read 703438 sequences (100000136 bp) in 2.340 CPU sec, 2.404 real sec...
sorting block 26, #reads = 1077075 mem = 536880567 peak = 886116352
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (101, 284583, 51, 77)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 311, 1117)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3029)
[M::mem_pestat] mean and std.dev: (499.10, 562.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3985)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 236, 349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 735)
[M::mem_pestat] mean and std.dev: (263.19, 136.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 928)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (539, 1223, 2368)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6026)
[M::mem_pestat] mean and std.dev: (1412.77, 1108.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7855)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 265, 392)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 804)
[M::mem_pestat] mean and std.dev: (286.71, 162.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1010)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703086 sequences (100000245 bp) in 3.461 CPU sec, 3.766 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (107, 284414, 48, 108)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 304, 635)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1549)
[M::mem_pestat] mean and std.dev: (329.42, 293.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2006)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 238, 351)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 741)
[M::mem_pestat] mean and std.dev: (264.73, 136.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 936)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (257, 666, 2842)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8012)
[M::mem_pestat] mean and std.dev: (1462.76, 2027.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10597)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (282, 361, 894)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2118)
[M::mem_pestat] mean and std.dev: (474.06, 332.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2730)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704034 reads in 196.687 CPU sec, 6.325 real sec
[M::mem_process_seqs] Processed 703438 reads in 129.707 CPU sec, 4.112 real sec
[M::process] read 702254 sequences (100000037 bp) in 2.368 CPU sec, 2.497 real sec...
sorting block 27, #reads = 1079796 mem = 536880649 peak = 886116352
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (108, 284250, 51, 100)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 304, 784)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1968)
[M::mem_pestat] mean and std.dev: (464.95, 443.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2560)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 240, 355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 751)
[M::mem_pestat] mean and std.dev: (267.05, 138.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 949)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (691, 1402, 1976)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4546)
[M::mem_pestat] mean and std.dev: (1251.12, 851.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5831)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 332, 795)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1993)
[M::mem_pestat] mean and std.dev: (389.56, 310.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2592)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701532 sequences (100000254 bp) in 3.259 CPU sec, 3.689 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (125, 284427, 60, 100)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 350, 1123)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2937)
[M::mem_pestat] mean and std.dev: (666.12, 705.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3844)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 243, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 761)
[M::mem_pestat] mean and std.dev: (270.28, 140.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 962)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (367, 753, 1284)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3118)
[M::mem_pestat] mean and std.dev: (796.94, 680.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4035)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 310, 746)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1862)
[M::mem_pestat] mean and std.dev: (396.87, 340.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2420)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703086 reads in 195.159 CPU sec, 6.288 real sec
sorting block 28, #reads = 1078424 mem = 536877357 peak = 886116352
[M::mem_process_seqs] Processed 702254 reads in 131.456 CPU sec, 4.205 real sec
[M::process] read 700254 sequences (100000118 bp) in 2.085 CPU sec, 2.208 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (101, 283849, 41, 111)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 289, 987)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2537)
[M::mem_pestat] mean and std.dev: (541.82, 562.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3312)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 245, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 769)
[M::mem_pestat] mean and std.dev: (272.54, 141.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 972)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 704, 2409)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6855)
[M::mem_pestat] mean and std.dev: (900.03, 1095.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9078)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 275, 600)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1356)
[M::mem_pestat] mean and std.dev: (373.05, 271.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1734)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 29, #reads = 1077310 mem = 536879494 peak = 886116352
[M::process] read 700140 sequences (100000032 bp) in 3.326 CPU sec, 3.739 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (99, 283542, 27, 90)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 306, 1074)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2866)
[M::mem_pestat] mean and std.dev: (474.89, 489.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3762)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 248, 368)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 780)
[M::mem_pestat] mean and std.dev: (276.07, 143.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 986)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (755, 1108, 3447)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8831)
[M::mem_pestat] mean and std.dev: (1918.85, 2024.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11523)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 283, 544)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1288)
[M::mem_pestat] mean and std.dev: (365.49, 275.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1660)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701532 reads in 192.500 CPU sec, 6.226 real sec
[M::mem_process_seqs] Processed 700254 reads in 132.653 CPU sec, 4.252 real sec
[M::process] read 699886 sequences (100000234 bp) in 2.903 CPU sec, 3.122 real sec...
sorting block 30, #reads = 1078067 mem = 536880247 peak = 886116352
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (95, 283066, 42, 89)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 302, 1825)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5147)
[M::mem_pestat] mean and std.dev: (666.86, 836.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6808)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 249, 368)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 780)
[M::mem_pestat] mean and std.dev: (276.51, 143.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 986)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (283, 585, 1960)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5314)
[M::mem_pestat] mean and std.dev: (1006.25, 1057.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6991)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 282, 486)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1128)
[M::mem_pestat] mean and std.dev: (311.80, 228.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1449)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699190 sequences (100000295 bp) in 2.540 CPU sec, 2.858 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (114, 283426, 27, 106)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 284, 554)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1304)
[M::mem_pestat] mean and std.dev: (293.46, 193.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1679)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 249, 368)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 778)
[M::mem_pestat] mean and std.dev: (276.24, 143.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 983)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (443, 957, 1402)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3320)
[M::mem_pestat] mean and std.dev: (959.42, 652.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4279)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 309, 605)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1425)
[M::mem_pestat] mean and std.dev: (407.26, 290.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1835)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700140 reads in 189.049 CPU sec, 6.089 real sec
[M::mem_process_seqs] Processed 699886 reads in 126.724 CPU sec, 4.032 real sec
[M::process] read 699328 sequences (100000212 bp) in 2.217 CPU sec, 2.344 real sec...
sorting block 31, #reads = 1077640 mem = 536881009 peak = 886116352
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (93, 283107, 50, 121)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 316, 718)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1790)
[M::mem_pestat] mean and std.dev: (436.78, 380.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2326)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 250, 369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 779)
[M::mem_pestat] mean and std.dev: (277.74, 143.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 984)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (476, 978, 1379)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3185)
[M::mem_pestat] mean and std.dev: (836.00, 584.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4088)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 342, 909)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2291)
[M::mem_pestat] mean and std.dev: (532.74, 445.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2982)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699032 sequences (100000053 bp) in 3.010 CPU sec, 3.363 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (114, 282567, 40, 110)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 298, 417)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 897)
[M::mem_pestat] mean and std.dev: (295.86, 162.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1137)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 248, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 772)
[M::mem_pestat] mean and std.dev: (275.61, 141.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 975)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (253, 931, 2017)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5545)
[M::mem_pestat] mean and std.dev: (1334.42, 1243.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7309)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 331, 445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 941)
[M::mem_pestat] mean and std.dev: (326.92, 181.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1189)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699190 reads in 185.771 CPU sec, 5.961 real sec
sorting block 32, #reads = 1077419 mem = 536883933 peak = 886116352
[M::process] read 699112 sequences (100000213 bp) in 2.137 CPU sec, 2.206 real sec...
[M::mem_process_seqs] Processed 699328 reads in 129.566 CPU sec, 4.244 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (112, 282767, 44, 95)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 242, 488)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1132)
[M::mem_pestat] mean and std.dev: (320.82, 225.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1454)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 249, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 773)
[M::mem_pestat] mean and std.dev: (276.78, 142.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 976)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (275, 1397, 2938)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8264)
[M::mem_pestat] mean and std.dev: (1709.23, 1671.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10927)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 266, 524)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1172)
[M::mem_pestat] mean and std.dev: (304.52, 168.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1496)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 33, #reads = 1077932 mem = 536880975 peak = 886116352
[M::process] read 699418 sequences (100000155 bp) in 2.543 CPU sec, 2.768 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (111, 283024, 46, 107)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 269, 569)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1311)
[M::mem_pestat] mean and std.dev: (292.93, 201.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1682)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 248, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 763)
[M::mem_pestat] mean and std.dev: (273.89, 139.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 963)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (367, 855, 3785)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10621)
[M::mem_pestat] mean and std.dev: (2026.78, 2252.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14039)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 333, 538)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1202)
[M::mem_pestat] mean and std.dev: (317.96, 171.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1534)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699020 sequences (100000300 bp) in 1.931 CPU sec, 1.941 real sec...
[M::mem_process_seqs] Processed 699032 reads in 188.072 CPU sec, 6.190 real sec
[M::mem_process_seqs] Processed 699112 reads in 126.610 CPU sec, 4.033 real sec
sorting block 34, #reads = 1075516 mem = 536884911 peak = 886116352
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (130, 283024, 51, 129)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 282, 605)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1493)
[M::mem_pestat] mean and std.dev: (349.77, 283.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1937)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 247, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 757)
[M::mem_pestat] mean and std.dev: (273.06, 139.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 955)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (94, 636, 1412)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4048)
[M::mem_pestat] mean and std.dev: (807.33, 909.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5366)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 369, 788)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1926)
[M::mem_pestat] mean and std.dev: (546.13, 480.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2495)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698818 sequences (100000284 bp) in 2.708 CPU sec, 3.054 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (126, 283044, 40, 132)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 287, 483)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1073)
[M::mem_pestat] mean and std.dev: (286.15, 149.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1368)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 248, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 764)
[M::mem_pestat] mean and std.dev: (274.53, 140.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 964)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (283, 664, 1195)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3019)
[M::mem_pestat] mean and std.dev: (712.65, 610.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3931)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 326, 754)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1878)
[M::mem_pestat] mean and std.dev: (405.28, 318.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2440)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699418 reads in 185.542 CPU sec, 6.040 real sec
[M::process] read 698692 sequences (100000095 bp) in 2.062 CPU sec, 2.109 real sec...
sorting block 35, #reads = 1076816 mem = 536878688 peak = 886116352
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (101, 282607, 47, 121)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 240, 826)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2142)
[M::mem_pestat] mean and std.dev: (439.61, 435.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2800)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 249, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 764)
[M::mem_pestat] mean and std.dev: (274.83, 139.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 964)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (235, 973, 1941)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5353)
[M::mem_pestat] mean and std.dev: (1172.11, 1300.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7059)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 349, 669)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1623)
[M::mem_pestat] mean and std.dev: (388.67, 301.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2100)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698046 sequences (100000236 bp) in 2.140 CPU sec, 2.189 real sec...
[M::mem_process_seqs] Processed 698818 reads in 106.116 CPU sec, 3.382 real sec
[M::mem_process_seqs] Processed 699020 reads in 270.561 CPU sec, 8.647 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (94, 282623, 50, 99)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 302, 957)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2481)
[M::mem_pestat] mean and std.dev: (515.65, 546.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3243)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 251, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 773)
[M::mem_pestat] mean and std.dev: (276.65, 141.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 976)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (418, 814, 1575)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3889)
[M::mem_pestat] mean and std.dev: (892.81, 803.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5046)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 317, 465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 967)
[M::mem_pestat] mean and std.dev: (315.47, 165.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1218)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 36, #reads = 1075060 mem = 536882916 peak = 886116352
[M::process] read 698290 sequences (100000218 bp) in 2.927 CPU sec, 3.416 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (100, 282581, 35, 123)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 272, 491)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1151)
[M::mem_pestat] mean and std.dev: (325.08, 219.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1481)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 252, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 771)
[M::mem_pestat] mean and std.dev: (277.17, 141.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 973)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 658, 2058)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5820)
[M::mem_pestat] mean and std.dev: (1058.43, 1170.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7701)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 341, 473)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 981)
[M::mem_pestat] mean and std.dev: (330.01, 162.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1235)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698692 reads in 206.376 CPU sec, 6.638 real sec
[M::mem_process_seqs] Processed 698046 reads in 126.567 CPU sec, 4.055 real sec
[M::process] read 703126 sequences (100000040 bp) in 2.310 CPU sec, 2.484 real sec...
sorting block 37, #reads = 1076671 mem = 536884499 peak = 886116352
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (99, 283130, 45, 112)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 372, 757)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1891)
[M::mem_pestat] mean and std.dev: (443.63, 374.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2458)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 251, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 768)
[M::mem_pestat] mean and std.dev: (276.37, 140.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 969)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (347, 889, 2466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6704)
[M::mem_pestat] mean and std.dev: (1420.91, 1547.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8823)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 315, 863)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2193)
[M::mem_pestat] mean and std.dev: (444.39, 417.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2858)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704456 sequences (100000250 bp) in 3.061 CPU sec, 3.327 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (94, 283681, 42, 119)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 392, 919)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2367)
[M::mem_pestat] mean and std.dev: (526.74, 511.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3091)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 239, 353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 745)
[M::mem_pestat] mean and std.dev: (266.02, 137.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 941)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (142, 802, 1249)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3463)
[M::mem_pestat] mean and std.dev: (770.18, 694.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4570)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 320, 546)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1204)
[M::mem_pestat] mean and std.dev: (359.10, 230.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1533)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698290 reads in 189.273 CPU sec, 6.068 real sec
[M::mem_process_seqs] Processed 703126 reads in 130.940 CPU sec, 4.158 real sec
sorting block 38, #reads = 1075477 mem = 536883153 peak = 886116352
[M::process] read 704110 sequences (100000112 bp) in 2.677 CPU sec, 2.819 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (129, 284765, 47, 99)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 288, 405)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 821)
[M::mem_pestat] mean and std.dev: (285.40, 154.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1029)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 235, 348)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 734)
[M::mem_pestat] mean and std.dev: (262.93, 137.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 927)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (118, 509, 1226)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3442)
[M::mem_pestat] mean and std.dev: (570.69, 575.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4550)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 353, 675)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1569)
[M::mem_pestat] mean and std.dev: (423.60, 278.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2016)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703188 sequences (100000004 bp) in 2.872 CPU sec, 3.164 real sec...
sorting block 39, #reads = 1075931 mem = 536882064 peak = 886116352
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (105, 284932, 57, 113)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 280, 754)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1926)
[M::mem_pestat] mean and std.dev: (427.97, 397.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2512)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 237, 353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 749)
[M::mem_pestat] mean and std.dev: (265.37, 138.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 947)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (675, 1148, 2938)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7464)
[M::mem_pestat] mean and std.dev: (1747.18, 1587.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9727)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 254, 994)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2574)
[M::mem_pestat] mean and std.dev: (485.65, 573.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3364)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 704456 reads in 187.785 CPU sec, 6.061 real sec
[M::mem_process_seqs] Processed 704110 reads in 129.888 CPU sec, 4.159 real sec
[M::process] read 702890 sequences (100000257 bp) in 2.319 CPU sec, 2.512 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (114, 284479, 37, 107)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 363, 922)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2412)
[M::mem_pestat] mean and std.dev: (585.77, 578.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3157)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 240, 355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 751)
[M::mem_pestat] mean and std.dev: (267.46, 139.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 949)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (324, 1062, 2918)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8106)
[M::mem_pestat] mean and std.dev: (1698.41, 1591.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10700)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 311, 554)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1222)
[M::mem_pestat] mean and std.dev: (363.51, 217.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1556)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 40, #reads = 1080550 mem = 536880581 peak = 886116352
[M::process] read 701646 sequences (100000212 bp) in 2.701 CPU sec, 3.016 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (84, 284706, 33, 98)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (143, 192, 458)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1088)
[M::mem_pestat] mean and std.dev: (266.73, 208.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1403)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 241, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 758)
[M::mem_pestat] mean and std.dev: (269.19, 140.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 958)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (604, 1573, 3159)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8269)
[M::mem_pestat] mean and std.dev: (1846.67, 1604.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10824)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 264, 579)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1395)
[M::mem_pestat] mean and std.dev: (340.53, 210.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1803)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703188 reads in 184.595 CPU sec, 5.965 real sec
[M::mem_process_seqs] Processed 702890 reads in 126.157 CPU sec, 4.055 real sec
[M::process] read 701280 sequences (100000138 bp) in 1.828 CPU sec, 1.991 real sec...
sorting block 41, #reads = 1080472 mem = 536883622 peak = 886116352
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (104, 283522, 49, 111)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 279, 1019)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2595)
[M::mem_pestat] mean and std.dev: (533.63, 531.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3383)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 244, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 768)
[M::mem_pestat] mean and std.dev: (271.95, 141.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 971)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (522, 1067, 2587)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6717)
[M::mem_pestat] mean and std.dev: (1301.05, 1397.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8782)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 347, 903)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2389)
[M::mem_pestat] mean and std.dev: (499.00, 467.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3132)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700674 sequences (100000121 bp) in 2.813 CPU sec, 3.158 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (82, 284206, 45, 100)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 330, 872)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2266)
[M::mem_pestat] mean and std.dev: (438.76, 433.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2963)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 246, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 775)
[M::mem_pestat] mean and std.dev: (273.89, 142.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 980)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (403, 1512, 2166)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5692)
[M::mem_pestat] mean and std.dev: (1284.15, 1259.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7455)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 328, 740)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1858)
[M::mem_pestat] mean and std.dev: (378.31, 352.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2417)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701646 reads in 188.655 CPU sec, 6.096 real sec
[M::mem_process_seqs] Processed 701280 reads in 126.748 CPU sec, 4.045 real sec
sorting block 42, #reads = 1078417 mem = 536879750 peak = 886116352
[M::process] read 699914 sequences (100000234 bp) in 2.788 CPU sec, 3.153 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (115, 283634, 27, 103)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (140, 250, 720)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1880)
[M::mem_pestat] mean and std.dev: (345.91, 330.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2460)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 247, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 776)
[M::mem_pestat] mean and std.dev: (275.27, 143.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 981)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (811, 1225, 3164)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7870)
[M::mem_pestat] mean and std.dev: (1820.00, 1506.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10223)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 272, 603)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1435)
[M::mem_pestat] mean and std.dev: (324.06, 218.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1851)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700124 sequences (100000085 bp) in 2.731 CPU sec, 3.034 real sec...
sorting block 43, #reads = 1078535 mem = 536884383 peak = 886116352
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (108, 283007, 55, 92)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 263, 673)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1681)
[M::mem_pestat] mean and std.dev: (354.34, 311.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2185)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 248, 368)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 780)
[M::mem_pestat] mean and std.dev: (276.70, 144.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 986)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (86, 826, 2027)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5909)
[M::mem_pestat] mean and std.dev: (952.87, 910.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7850)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (257, 331, 793)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1865)
[M::mem_pestat] mean and std.dev: (381.23, 244.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2401)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700674 reads in 190.026 CPU sec, 6.178 real sec
[M::mem_process_seqs] Processed 699914 reads in 129.487 CPU sec, 4.137 real sec
[M::process] read 699822 sequences (100000095 bp) in 2.542 CPU sec, 2.754 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (91, 283295, 52, 120)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 325, 1352)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3692)
[M::mem_pestat] mean and std.dev: (559.20, 599.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4862)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 248, 368)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 780)
[M::mem_pestat] mean and std.dev: (276.63, 144.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 986)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (466, 1317, 2558)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6742)
[M::mem_pestat] mean and std.dev: (1519.49, 1519.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8834)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 333, 748)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1832)
[M::mem_pestat] mean and std.dev: (447.28, 383.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2374)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 44, #reads = 1078550 mem = 536878303 peak = 886116352
[M::process] read 700090 sequences (100000294 bp) in 2.935 CPU sec, 3.244 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (113, 282963, 47, 109)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 332, 810)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2024)
[M::mem_pestat] mean and std.dev: (435.68, 360.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2631)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 247, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 774)
[M::mem_pestat] mean and std.dev: (275.30, 142.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 978)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (293, 1102, 2368)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6518)
[M::mem_pestat] mean and std.dev: (1312.89, 1391.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8593)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 339, 599)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1457)
[M::mem_pestat] mean and std.dev: (375.92, 271.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1886)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700124 reads in 188.859 CPU sec, 6.099 real sec
[M::mem_process_seqs] Processed 699822 reads in 130.793 CPU sec, 4.166 real sec
[M::process] read 700482 sequences (100000065 bp) in 2.396 CPU sec, 2.544 real sec...
sorting block 45, #reads = 1077539 mem = 536879328 peak = 886116352
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (81, 283845, 64, 104)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 301, 682)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1682)
[M::mem_pestat] mean and std.dev: (449.48, 413.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2182)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 245, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 767)
[M::mem_pestat] mean and std.dev: (273.60, 142.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 969)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (277, 782, 1707)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4567)
[M::mem_pestat] mean and std.dev: (1102.79, 1120.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5997)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (230, 365, 932)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2336)
[M::mem_pestat] mean and std.dev: (527.10, 434.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3038)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700566 sequences (100000227 bp) in 2.738 CPU sec, 3.098 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (121, 283117, 47, 104)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 312, 768)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1920)
[M::mem_pestat] mean and std.dev: (418.64, 364.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2496)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 243, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 758)
[M::mem_pestat] mean and std.dev: (271.47, 140.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 957)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (565, 1028, 3030)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7960)
[M::mem_pestat] mean and std.dev: (1701.47, 1685.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10425)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 292, 514)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1126)
[M::mem_pestat] mean and std.dev: (335.23, 218.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1432)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700090 reads in 188.994 CPU sec, 6.108 real sec
[M::mem_process_seqs] Processed 700482 reads in 129.681 CPU sec, 4.144 real sec
sorting block 46, #reads = 1077553 mem = 536879375 peak = 886116352
[M::process] read 700528 sequences (100000126 bp) in 2.647 CPU sec, 2.798 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (104, 284193, 31, 82)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 330, 853)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2153)
[M::mem_pestat] mean and std.dev: (401.86, 373.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2803)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 244, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 755)
[M::mem_pestat] mean and std.dev: (270.98, 139.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 953)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 530, 1150)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3118)
[M::mem_pestat] mean and std.dev: (625.59, 666.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4102)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 263, 610)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1494)
[M::mem_pestat] mean and std.dev: (351.68, 267.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1936)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (103, 283547, 48, 118)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 236, 469)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1053)
[M::mem_pestat] mean and std.dev: (317.98, 225.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1345)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 244, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 754)
[M::mem_pestat] mean and std.dev: (270.75, 139.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 952)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (293, 1103, 1960)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5294)
[M::mem_pestat] mean and std.dev: (964.88, 889.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6961)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 320, 631)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1463)
[M::mem_pestat] mean and std.dev: (323.15, 198.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1879)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700044 sequences (100000231 bp) in 3.662 CPU sec, 4.059 real sec...
[M::mem_process_seqs] Processed 700566 reads in 186.470 CPU sec, 6.016 real sec
sorting block 47, #reads = 1078139 mem = 536880044 peak = 886116352
[M::mem_process_seqs] Processed 700528 reads in 130.178 CPU sec, 4.147 real sec
[M::process] read 699852 sequences (100000190 bp) in 2.769 CPU sec, 3.016 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (100, 283318, 40, 103)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 299, 569)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1361)
[M::mem_pestat] mean and std.dev: (312.93, 204.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1757)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 245, 357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 747)
[M::mem_pestat] mean and std.dev: (270.74, 138.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 942)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (256, 650, 2496)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6976)
[M::mem_pestat] mean and std.dev: (1344.49, 1601.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9216)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 280, 506)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1180)
[M::mem_pestat] mean and std.dev: (311.47, 207.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1517)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 48, #reads = 1078082 mem = 536877307 peak = 886116352
[M::process] read 699568 sequences (100000180 bp) in 2.973 CPU sec, 3.255 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (126, 283009, 31, 104)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 301, 933)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2431)
[M::mem_pestat] mean and std.dev: (458.54, 445.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3180)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 246, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 756)
[M::mem_pestat] mean and std.dev: (272.12, 138.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 954)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (510, 718, 1220)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2640)
[M::mem_pestat] mean and std.dev: (695.15, 445.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3350)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 348, 501)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1045)
[M::mem_pestat] mean and std.dev: (340.42, 193.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1317)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700044 reads in 189.348 CPU sec, 6.125 real sec
[M::mem_process_seqs] Processed 699852 reads in 129.573 CPU sec, 4.201 real sec
[M::process] read 699264 sequences (100000124 bp) in 2.612 CPU sec, 2.892 real sec...
sorting block 49, #reads = 1077036 mem = 536881484 peak = 886116352
[M::process] read 699212 sequences (100000152 bp) in 2.973 CPU sec, 3.369 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (110, 283564, 37, 98)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (235, 375, 1005)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2545)
[M::mem_pestat] mean and std.dev: (582.63, 505.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3315)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 248, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 766)
[M::mem_pestat] mean and std.dev: (274.70, 141.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 967)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (479, 922, 2499)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6539)
[M::mem_pestat] mean and std.dev: (1260.75, 1170.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8559)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 334, 822)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2094)
[M::mem_pestat] mean and std.dev: (501.95, 457.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2730)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699264 reads in 106.515 CPU sec, 3.493 real sec
[M::process] read 701382 sequences (100000171 bp) in 2.669 CPU sec, 2.951 real sec...
sorting block 50, #reads = 1077772 mem = 536878914 peak = 886116352
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (98, 283310, 49, 77)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 285, 893)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2355)
[M::mem_pestat] mean and std.dev: (554.11, 597.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3086)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 248, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 760)
[M::mem_pestat] mean and std.dev: (273.39, 139.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 959)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (361, 663, 3345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9313)
[M::mem_pestat] mean and std.dev: (2008.37, 2283.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12297)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 282, 412)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 846)
[M::mem_pestat] mean and std.dev: (283.91, 119.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1063)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (130, 282994, 60, 126)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 304, 656)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1578)
[M::mem_pestat] mean and std.dev: (415.63, 320.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2039)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 248, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 763)
[M::mem_pestat] mean and std.dev: (274.38, 140.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 963)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (380, 952, 2997)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8231)
[M::mem_pestat] mean and std.dev: (1666.60, 1824.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10848)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 352, 747)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1903)
[M::mem_pestat] mean and std.dev: (387.86, 295.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2481)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699568 reads in 297.448 CPU sec, 9.670 real sec
[M::mem_process_seqs] Processed 699212 reads in 153.012 CPU sec, 4.987 real sec
[M::process] read 708676 sequences (100000166 bp) in 2.986 CPU sec, 3.165 real sec...
sorting block 51, #reads = 1076092 mem = 536877187 peak = 886116352
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (98, 283540, 41, 86)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 337, 907)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2335)
[M::mem_pestat] mean and std.dev: (510.78, 509.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3049)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 242, 356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 750)
[M::mem_pestat] mean and std.dev: (268.92, 138.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 947)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (466, 907, 1675)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4093)
[M::mem_pestat] mean and std.dev: (945.84, 779.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5302)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 295, 916)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2356)
[M::mem_pestat] mean and std.dev: (462.93, 434.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3076)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 708466 sequences (100000156 bp) in 2.833 CPU sec, 3.123 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (80, 286023, 37, 85)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 258, 508)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1186)
[M::mem_pestat] mean and std.dev: (289.69, 202.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1525)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 221, 327)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 685)
[M::mem_pestat] mean and std.dev: (249.17, 130.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 864)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 777, 1583)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4347)
[M::mem_pestat] mean and std.dev: (886.03, 831.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5729)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 293, 843)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2129)
[M::mem_pestat] mean and std.dev: (393.54, 356.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2772)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701382 reads in 204.789 CPU sec, 6.559 real sec
[M::process] read 706744 sequences (100000015 bp) in 2.147 CPU sec, 2.192 real sec...
[M::mem_process_seqs] Processed 708676 reads in 140.906 CPU sec, 4.475 real sec
sorting block 52, #reads = 1075947 mem = 536880580 peak = 886116352
[M::process] read 706192 sequences (100000183 bp) in 3.392 CPU sec, 3.672 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (78, 285794, 43, 103)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 277, 409)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 899)
[M::mem_pestat] mean and std.dev: (269.06, 143.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1144)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 226, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 706)
[M::mem_pestat] mean and std.dev: (255.30, 134.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 891)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 922, 2138)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6096)
[M::mem_pestat] mean and std.dev: (1265.57, 1307.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8075)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 287, 692)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1702)
[M::mem_pestat] mean and std.dev: (406.98, 343.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2207)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 706744 reads in 112.169 CPU sec, 3.547 real sec
[M::process] read 706604 sequences (100000061 bp) in 2.245 CPU sec, 2.316 real sec...
sorting block 53, #reads = 1077355 mem = 536879978 peak = 886116352
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (92, 286767, 36, 105)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 300, 782)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2052)
[M::mem_pestat] mean and std.dev: (413.34, 426.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2687)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 222, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 692)
[M::mem_pestat] mean and std.dev: (250.42, 130.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 873)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (702, 1132, 2758)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6870)
[M::mem_pestat] mean and std.dev: (1369.85, 1289.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8926)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 312, 600)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1424)
[M::mem_pestat] mean and std.dev: (371.72, 266.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1836)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (97, 285642, 36, 93)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 254, 608)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1476)
[M::mem_pestat] mean and std.dev: (350.52, 280.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1910)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 227, 339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 713)
[M::mem_pestat] mean and std.dev: (257.28, 135.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 900)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (514, 1641, 3777)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10303)
[M::mem_pestat] mean and std.dev: (2412.69, 2130.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13566)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 296, 657)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1585)
[M::mem_pestat] mean and std.dev: (332.34, 229.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2049)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 708466 reads in 311.725 CPU sec, 9.955 real sec
[M::process] read 705278 sequences (100000161 bp) in 2.363 CPU sec, 2.488 real sec...
[M::mem_process_seqs] Processed 706192 reads in 155.923 CPU sec, 5.178 real sec
sorting block 54, #reads = 1078741 mem = 536877109 peak = 886116352
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (95, 285976, 48, 106)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 324, 518)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1184)
[M::mem_pestat] mean and std.dev: (370.11, 258.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1517)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 224, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 697)
[M::mem_pestat] mean and std.dev: (253.36, 132.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 879)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (350, 835, 2926)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8078)
[M::mem_pestat] mean and std.dev: (1572.09, 1869.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10654)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 282, 696)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1694)
[M::mem_pestat] mean and std.dev: (397.00, 328.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2193)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703922 sequences (100000130 bp) in 2.987 CPU sec, 3.471 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (83, 285554, 35, 103)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 246, 620)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1538)
[M::mem_pestat] mean and std.dev: (349.84, 300.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1997)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 230, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 726)
[M::mem_pestat] mean and std.dev: (259.84, 136.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 917)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (433, 932, 3501)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9637)
[M::mem_pestat] mean and std.dev: (1980.31, 2065.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12705)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 292, 482)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1070)
[M::mem_pestat] mean and std.dev: (313.75, 180.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1364)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 706604 reads in 196.921 CPU sec, 6.557 real sec
[M::process] read 704126 sequences (100000189 bp) in 2.392 CPU sec, 2.468 real sec...
sorting block 55, #reads = 1081031 mem = 536878253 peak = 886116352
[M::mem_process_seqs] Processed 705278 reads in 139.992 CPU sec, 4.468 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (100, 284767, 35, 97)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (230, 328, 931)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2333)
[M::mem_pestat] mean and std.dev: (486.07, 454.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3034)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 235, 352)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 746)
[M::mem_pestat] mean and std.dev: (265.19, 140.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 943)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (411, 1025, 2575)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6903)
[M::mem_pestat] mean and std.dev: (1259.42, 1179.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9067)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (270, 354, 679)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1497)
[M::mem_pestat] mean and std.dev: (444.71, 269.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1906)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 56, #reads = 1078578 mem = 536877600 peak = 886116352
[M::process] read 705124 sequences (100000282 bp) in 3.082 CPU sec, 3.459 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (121, 284972, 50, 131)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 281, 595)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1427)
[M::mem_pestat] mean and std.dev: (323.58, 216.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1843)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 234, 353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 749)
[M::mem_pestat] mean and std.dev: (265.58, 140.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 947)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (322, 651, 1503)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3865)
[M::mem_pestat] mean and std.dev: (912.04, 961.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5046)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 383, 590)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1358)
[M::mem_pestat] mean and std.dev: (388.99, 236.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1742)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703922 reads in 201.295 CPU sec, 6.497 real sec
[M::mem_process_seqs] Processed 704126 reads in 137.500 CPU sec, 4.395 real sec
[M::process] read 702650 sequences (100000009 bp) in 3.105 CPU sec, 3.270 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (105, 284843, 25, 111)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 341, 814)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2092)
[M::mem_pestat] mean and std.dev: (465.57, 427.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2731)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 230, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 723)
[M::mem_pestat] mean and std.dev: (259.39, 135.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 913)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (233, 643, 1269)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3341)
[M::mem_pestat] mean and std.dev: (608.95, 483.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4377)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 300, 515)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1121)
[M::mem_pestat] mean and std.dev: (307.63, 162.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1424)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 57, #reads = 1077183 mem = 536880955 peak = 886116352
[M::process] read 703314 sequences (100000148 bp) in 3.047 CPU sec, 3.446 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (102, 283858, 42, 98)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 288, 698)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1750)
[M::mem_pestat] mean and std.dev: (386.02, 337.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2276)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 237, 353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 745)
[M::mem_pestat] mean and std.dev: (266.24, 139.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 941)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (283, 1353, 3520)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9994)
[M::mem_pestat] mean and std.dev: (2013.52, 2098.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13231)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 343, 813)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2009)
[M::mem_pestat] mean and std.dev: (377.55, 299.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2607)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 705124 reads in 204.335 CPU sec, 6.686 real sec
[M::process] read 701748 sequences (100000051 bp) in 2.082 CPU sec, 2.166 real sec...
[M::mem_process_seqs] Processed 702650 reads in 139.187 CPU sec, 4.774 real sec
sorting block 58, #reads = 1076993 mem = 536877826 peak = 886116352
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (115, 284892, 31, 97)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 321, 874)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2258)
[M::mem_pestat] mean and std.dev: (497.69, 533.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2950)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 237, 355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 753)
[M::mem_pestat] mean and std.dev: (267.48, 141.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 952)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 609, 1847)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5127)
[M::mem_pestat] mean and std.dev: (1069.11, 1167.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6767)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 335, 563)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1235)
[M::mem_pestat] mean and std.dev: (343.39, 216.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1571)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700274 sequences (100000129 bp) in 2.804 CPU sec, 3.039 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (96, 284364, 26, 68)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 333, 766)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1938)
[M::mem_pestat] mean and std.dev: (433.98, 387.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2524)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 241, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 767)
[M::mem_pestat] mean and std.dev: (271.06, 141.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 970)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (417, 1243, 2063)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5355)
[M::mem_pestat] mean and std.dev: (1551.16, 1383.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7085)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 348, 1400)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3762)
[M::mem_pestat] mean and std.dev: (862.94, 1076.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5168)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699088 sequences (100000174 bp) in 2.013 CPU sec, 2.029 real sec...
[M::mem_process_seqs] Processed 703314 reads in 206.011 CPU sec, 6.752 real sec
sorting block 59, #reads = 1075799 mem = 536883028 peak = 886116352
[M::mem_process_seqs] Processed 701748 reads in 134.856 CPU sec, 4.354 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (81, 283286, 51, 119)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 341, 889)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2281)
[M::mem_pestat] mean and std.dev: (468.21, 453.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2977)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 246, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 771)
[M::mem_pestat] mean and std.dev: (274.63, 142.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 974)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (533, 1278, 4965)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13829)
[M::mem_pestat] mean and std.dev: (2798.43, 2961.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 18261)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 356, 420)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 856)
[M::mem_pestat] mean and std.dev: (289.76, 129.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1074)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 60, #reads = 1075603 mem = 536878932 peak = 886116352
[M::process] read 698598 sequences (100000124 bp) in 3.230 CPU sec, 3.598 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (93, 283179, 40, 138)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 341, 764)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1904)
[M::mem_pestat] mean and std.dev: (393.96, 328.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2474)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 248, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 775)
[M::mem_pestat] mean and std.dev: (276.24, 142.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 979)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (366, 1079, 1752)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4524)
[M::mem_pestat] mean and std.dev: (1149.08, 1018.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5910)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (241, 362, 764)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1810)
[M::mem_pestat] mean and std.dev: (434.62, 352.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2333)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700274 reads in 207.806 CPU sec, 6.737 real sec
[M::process] read 698148 sequences (100000146 bp) in 2.182 CPU sec, 2.226 real sec...
[M::mem_process_seqs] Processed 699088 reads in 149.877 CPU sec, 4.774 real sec
sorting block 61, #reads = 1072922 mem = 536879913 peak = 886116352
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (109, 283327, 44, 107)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 349, 947)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2451)
[M::mem_pestat] mean and std.dev: (530.17, 482.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3203)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 252, 371)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 783)
[M::mem_pestat] mean and std.dev: (279.56, 144.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 989)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (510, 1296, 2799)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7377)
[M::mem_pestat] mean and std.dev: (1624.17, 1536.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9666)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 330, 1000)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2620)
[M::mem_pestat] mean and std.dev: (478.18, 519.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3430)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698508 sequences (100000205 bp) in 2.846 CPU sec, 3.265 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (104, 282884, 35, 129)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 295, 473)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1027)
[M::mem_pestat] mean and std.dev: (322.07, 196.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1304)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 251, 370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 780)
[M::mem_pestat] mean and std.dev: (278.24, 142.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 985)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (389, 691, 2083)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5471)
[M::mem_pestat] mean and std.dev: (1161.09, 1308.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7165)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 330, 664)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1614)
[M::mem_pestat] mean and std.dev: (390.43, 319.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2089)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698598 reads in 205.361 CPU sec, 6.599 real sec
[M::process] read 700168 sequences (100000274 bp) in 2.322 CPU sec, 2.365 real sec...
[M::mem_process_seqs] Processed 698148 reads in 142.132 CPU sec, 4.545 real sec
sorting block 62, #reads = 1072849 mem = 536877638 peak = 886116352
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (128, 283019, 66, 131)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 300, 384)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 774)
[M::mem_pestat] mean and std.dev: (274.98, 133.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 969)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 250, 369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 779)
[M::mem_pestat] mean and std.dev: (278.38, 143.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 984)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 568, 1173)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3207)
[M::mem_pestat] mean and std.dev: (592.72, 525.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4224)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (236, 348, 819)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1985)
[M::mem_pestat] mean and std.dev: (429.03, 305.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2568)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 711602 sequences (100000124 bp) in 3.045 CPU sec, 3.415 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (118, 282653, 49, 110)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 360, 753)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1843)
[M::mem_pestat] mean and std.dev: (406.02, 283.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2388)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 246, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 776)
[M::mem_pestat] mean and std.dev: (275.27, 143.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 981)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 584, 1382)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3722)
[M::mem_pestat] mean and std.dev: (886.22, 958.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4892)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 288, 802)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2018)
[M::mem_pestat] mean and std.dev: (409.44, 404.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2626)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 712148 sequences (100000084 bp) in 2.142 CPU sec, 2.147 real sec...
[M::mem_process_seqs] Processed 698508 reads in 211.404 CPU sec, 6.796 real sec
sorting block 63, #reads = 1070859 mem = 536878572 peak = 886116352
[M::mem_process_seqs] Processed 700168 reads in 145.718 CPU sec, 4.645 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (86, 287298, 41, 87)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 273, 416)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 928)
[M::mem_pestat] mean and std.dev: (268.18, 157.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1184)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 215, 316)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 658)
[M::mem_pestat] mean and std.dev: (241.49, 124.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 829)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (251, 610, 1564)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4190)
[M::mem_pestat] mean and std.dev: (836.86, 880.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5503)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 348, 738)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1794)
[M::mem_pestat] mean and std.dev: (420.04, 361.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2322)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 64, #reads = 1071451 mem = 536882379 peak = 886116352
[M::process] read 708702 sequences (100000030 bp) in 3.104 CPU sec, 3.414 real sec...
[M::process] read 707766 sequences (100000192 bp) in 2.177 CPU sec, 2.199 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (96, 287485, 40, 125)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 265, 566)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1328)
[M::mem_pestat] mean and std.dev: (275.41, 180.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1709)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 214, 315)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 655)
[M::mem_pestat] mean and std.dev: (240.74, 123.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 825)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 846, 2258)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6356)
[M::mem_pestat] mean and std.dev: (1291.87, 1492.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8405)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 303, 626)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1504)
[M::mem_pestat] mean and std.dev: (347.88, 274.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1943)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 711602 reads in 227.482 CPU sec, 7.280 real sec
[M::mem_process_seqs] Processed 712148 reads in 152.905 CPU sec, 4.876 real sec
sorting block 65, #reads = 1075593 mem = 536879503 peak = 886116352
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (88, 286794, 45, 105)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (146, 219, 393)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 887)
[M::mem_pestat] mean and std.dev: (247.24, 148.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1134)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 222, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 686)
[M::mem_pestat] mean and std.dev: (249.42, 128.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 865)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (543, 1048, 1740)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4134)
[M::mem_pestat] mean and std.dev: (1123.74, 875.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5331)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 277, 494)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1090)
[M::mem_pestat] mean and std.dev: (269.74, 131.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1388)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705794 sequences (100000113 bp) in 3.316 CPU sec, 3.713 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (107, 286135, 26, 88)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 260, 594)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1424)
[M::mem_pestat] mean and std.dev: (362.04, 317.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1839)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 224, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 699)
[M::mem_pestat] mean and std.dev: (252.75, 131.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 882)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 793, 2365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6679)
[M::mem_pestat] mean and std.dev: (1305.15, 1378.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8836)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 327, 693)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1675)
[M::mem_pestat] mean and std.dev: (414.52, 327.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2166)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 708702 reads in 219.342 CPU sec, 7.182 real sec
[M::process] read 705258 sequences (100000279 bp) in 2.282 CPU sec, 2.333 real sec...
[M::mem_process_seqs] Processed 707766 reads in 146.500 CPU sec, 4.835 real sec
sorting block 66, #reads = 1074198 mem = 536878714 peak = 886116352
[M::process] read 704528 sequences (100000131 bp) in 3.056 CPU sec, 3.414 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (97, 285213, 46, 94)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 256, 597)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1443)
[M::mem_pestat] mean and std.dev: (315.65, 259.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1866)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 231, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 726)
[M::mem_pestat] mean and std.dev: (260.01, 135.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 917)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (239, 598, 933)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2321)
[M::mem_pestat] mean and std.dev: (575.00, 477.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3015)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 339, 477)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1025)
[M::mem_pestat] mean and std.dev: (339.04, 186.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1299)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703958 sequences (100000165 bp) in 2.052 CPU sec, 2.137 real sec...
[M::mem_process_seqs] Processed 705258 reads in 122.917 CPU sec, 3.901 real sec
sorting block 67, #reads = 1075535 mem = 536878010 peak = 886116352
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (97, 285235, 21, 82)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 330, 1062)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2760)
[M::mem_pestat] mean and std.dev: (510.61, 527.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3609)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 229, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 719)
[M::mem_pestat] mean and std.dev: (257.82, 133.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 908)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (518, 715, 1706)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4082)
[M::mem_pestat] mean and std.dev: (894.35, 834.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5270)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 291, 789)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1917)
[M::mem_pestat] mean and std.dev: (456.33, 399.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2481)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (123, 285185, 36, 105)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 282, 544)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1308)
[M::mem_pestat] mean and std.dev: (311.84, 217.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1690)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 233, 347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 733)
[M::mem_pestat] mean and std.dev: (262.10, 136.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 926)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (821, 1215, 2076)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4586)
[M::mem_pestat] mean and std.dev: (1282.82, 894.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5841)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (233, 335, 915)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2279)
[M::mem_pestat] mean and std.dev: (506.60, 463.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2961)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703712 sequences (100000241 bp) in 2.270 CPU sec, 2.277 real sec...
[M::mem_process_seqs] Processed 705794 reads in 339.008 CPU sec, 11.034 real sec
[M::mem_process_seqs] Processed 704528 reads in 175.978 CPU sec, 5.653 real sec
sorting block 68, #reads = 1075163 mem = 536882695 peak = 886116352
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (113, 285372, 35, 96)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 399, 1037)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2669)
[M::mem_pestat] mean and std.dev: (593.60, 578.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3485)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 234, 349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 737)
[M::mem_pestat] mean and std.dev: (263.28, 136.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 931)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (271, 740, 2260)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6238)
[M::mem_pestat] mean and std.dev: (1242.59, 1181.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8227)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 281, 734)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1832)
[M::mem_pestat] mean and std.dev: (449.07, 375.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2381)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702964 sequences (100000189 bp) in 3.335 CPU sec, 3.828 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (91, 285077, 49, 105)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 351, 1010)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2642)
[M::mem_pestat] mean and std.dev: (562.38, 612.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3458)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 234, 349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 737)
[M::mem_pestat] mean and std.dev: (263.38, 136.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 931)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (238, 842, 2953)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8383)
[M::mem_pestat] mean and std.dev: (1625.63, 2323.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11098)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 319, 537)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1241)
[M::mem_pestat] mean and std.dev: (341.65, 213.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1593)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 703958 reads in 210.806 CPU sec, 6.852 real sec
[M::process] read 702992 sequences (100000136 bp) in 2.322 CPU sec, 2.464 real sec...
[M::mem_process_seqs] Processed 703712 reads in 141.147 CPU sec, 4.504 real sec
sorting block 69, #reads = 1072341 mem = 536881235 peak = 886116352
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (118, 284888, 43, 73)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 250, 674)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1728)
[M::mem_pestat] mean and std.dev: (371.44, 361.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2255)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 238, 355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 751)
[M::mem_pestat] mean and std.dev: (267.44, 139.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 949)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (361, 848, 1528)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3862)
[M::mem_pestat] mean and std.dev: (1012.70, 849.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5029)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 277, 476)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1048)
[M::mem_pestat] mean and std.dev: (287.18, 152.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1334)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 70, #reads = 1075157 mem = 536878673 peak = 886116352
[M::process] read 701510 sequences (100000114 bp) in 3.012 CPU sec, 3.434 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (116, 284609, 43, 119)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 304, 806)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2048)
[M::mem_pestat] mean and std.dev: (425.10, 412.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2669)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 236, 353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 747)
[M::mem_pestat] mean and std.dev: (266.04, 139.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 944)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (391, 968, 2258)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5992)
[M::mem_pestat] mean and std.dev: (1419.37, 1496.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7859)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 375, 624)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1416)
[M::mem_pestat] mean and std.dev: (387.91, 233.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1812)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699956 sequences (100000007 bp) in 2.057 CPU sec, 2.076 real sec...
[M::mem_process_seqs] Processed 702964 reads in 215.078 CPU sec, 6.928 real sec
[M::mem_process_seqs] Processed 702992 reads in 141.795 CPU sec, 4.518 real sec
sorting block 71, #reads = 1075165 mem = 536880468 peak = 886116352
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (105, 283767, 50, 85)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 285, 734)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1900)
[M::mem_pestat] mean and std.dev: (381.20, 375.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2483)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 242, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 768)
[M::mem_pestat] mean and std.dev: (271.97, 142.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 971)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (695, 1094, 1631)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3503)
[M::mem_pestat] mean and std.dev: (1001.25, 596.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4439)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 305, 922)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2348)
[M::mem_pestat] mean and std.dev: (457.86, 405.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3061)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699302 sequences (100000130 bp) in 2.992 CPU sec, 3.347 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (103, 283251, 45, 113)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 371, 900)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2310)
[M::mem_pestat] mean and std.dev: (607.89, 607.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3037)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 248, 370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 786)
[M::mem_pestat] mean and std.dev: (277.49, 145.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 994)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 366, 2811)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8087)
[M::mem_pestat] mean and std.dev: (1252.09, 1441.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10725)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 306, 757)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1867)
[M::mem_pestat] mean and std.dev: (387.48, 265.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2422)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701510 reads in 205.413 CPU sec, 6.644 real sec
[M::process] read 699290 sequences (100000026 bp) in 2.496 CPU sec, 2.579 real sec...
[M::mem_process_seqs] Processed 699956 reads in 139.540 CPU sec, 4.607 real sec
sorting block 72, #reads = 1074686 mem = 536878337 peak = 886116352
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (121, 282711, 61, 112)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 294, 540)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1262)
[M::mem_pestat] mean and std.dev: (324.68, 236.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1623)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 248, 369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 783)
[M::mem_pestat] mean and std.dev: (277.39, 144.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 990)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (384, 560, 1887)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4893)
[M::mem_pestat] mean and std.dev: (1268.95, 1291.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6437)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (253, 367, 880)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2134)
[M::mem_pestat] mean and std.dev: (504.49, 409.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2761)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699320 sequences (100000165 bp) in 3.096 CPU sec, 3.510 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (101, 283271, 31, 122)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 344, 721)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1805)
[M::mem_pestat] mean and std.dev: (453.18, 395.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2347)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 247, 369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 781)
[M::mem_pestat] mean and std.dev: (277.75, 145.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 987)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 595, 1011)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2631)
[M::mem_pestat] mean and std.dev: (656.24, 603.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3441)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 351, 1375)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3685)
[M::mem_pestat] mean and std.dev: (708.51, 798.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4840)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699302 reads in 203.035 CPU sec, 6.711 real sec
[M::process] read 699850 sequences (100000097 bp) in 2.215 CPU sec, 2.263 real sec...
sorting block 73, #reads = 1073100 mem = 536880470 peak = 886116352
[M::mem_process_seqs] Processed 699290 reads in 139.128 CPU sec, 4.612 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (114, 282290, 56, 125)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 271, 469)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1007)
[M::mem_pestat] mean and std.dev: (281.21, 150.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1276)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 246, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 772)
[M::mem_pestat] mean and std.dev: (275.83, 143.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 975)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 514, 1047)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2843)
[M::mem_pestat] mean and std.dev: (530.52, 504.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3741)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 373, 829)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2055)
[M::mem_pestat] mean and std.dev: (502.45, 472.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2668)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 74, #reads = 1073222 mem = 536878388 peak = 886116352
[M::process] read 708698 sequences (100000008 bp) in 2.999 CPU sec, 3.436 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (98, 282503, 57, 121)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 280, 738)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1872)
[M::mem_pestat] mean and std.dev: (374.58, 351.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2439)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 245, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 765)
[M::mem_pestat] mean and std.dev: (274.22, 143.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 966)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (230, 592, 1422)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3806)
[M::mem_pestat] mean and std.dev: (673.86, 618.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4998)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 339, 948)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2458)
[M::mem_pestat] mean and std.dev: (491.56, 477.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3213)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 708712 sequences (100000063 bp) in 2.029 CPU sec, 2.046 real sec...
[M::mem_process_seqs] Processed 699320 reads in 218.771 CPU sec, 7.233 real sec
[M::mem_process_seqs] Processed 699850 reads in 149.100 CPU sec, 4.752 real sec
sorting block 75, #reads = 1070925 mem = 536879810 peak = 886116352
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (107, 285818, 41, 85)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 296, 1279)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3489)
[M::mem_pestat] mean and std.dev: (657.18, 687.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4594)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 222, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 689)
[M::mem_pestat] mean and std.dev: (249.91, 130.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 869)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (268, 602, 959)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2341)
[M::mem_pestat] mean and std.dev: (633.55, 485.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3032)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 299, 1015)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2671)
[M::mem_pestat] mean and std.dev: (476.69, 493.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3499)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706690 sequences (100000296 bp) in 2.946 CPU sec, 3.299 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (82, 286458, 36, 103)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 411, 761)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1895)
[M::mem_pestat] mean and std.dev: (517.09, 444.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2462)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 221, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 691)
[M::mem_pestat] mean and std.dev: (249.64, 129.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 872)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 632, 2587)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7425)
[M::mem_pestat] mean and std.dev: (1284.31, 1306.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9844)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 319, 492)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1082)
[M::mem_pestat] mean and std.dev: (341.43, 195.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1377)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 708698 reads in 215.194 CPU sec, 6.981 real sec
[M::process] read 705576 sequences (100000167 bp) in 3.021 CPU sec, 3.062 real sec...
[M::mem_process_seqs] Processed 708712 reads in 140.526 CPU sec, 4.648 real sec
sorting block 76, #reads = 1069583 mem = 536881411 peak = 886116352
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (113, 285715, 45, 97)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 348, 1012)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2630)
[M::mem_pestat] mean and std.dev: (595.54, 643.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3439)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 227, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 709)
[M::mem_pestat] mean and std.dev: (255.46, 132.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 895)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (487, 926, 1958)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4900)
[M::mem_pestat] mean and std.dev: (1146.34, 1062.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6371)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 318, 691)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1641)
[M::mem_pestat] mean and std.dev: (405.38, 347.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2116)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705300 sequences (100000127 bp) in 2.808 CPU sec, 3.294 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (79, 285468, 26, 97)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 239, 414)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 904)
[M::mem_pestat] mean and std.dev: (260.67, 143.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1149)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 230, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 723)
[M::mem_pestat] mean and std.dev: (258.95, 134.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 913)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (100, 579, 1364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3892)
[M::mem_pestat] mean and std.dev: (923.48, 964.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5156)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 333, 1033)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2699)
[M::mem_pestat] mean and std.dev: (593.56, 617.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3532)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 704424 sequences (100000051 bp) in 2.083 CPU sec, 2.094 real sec...
[M::mem_process_seqs] Processed 706690 reads in 199.112 CPU sec, 6.603 real sec
[M::mem_process_seqs] Processed 705576 reads in 131.777 CPU sec, 4.267 real sec
sorting block 77, #reads = 1077665 mem = 536881340 peak = 886116352
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (90, 285292, 32, 106)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 312, 569)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1365)
[M::mem_pestat] mean and std.dev: (331.92, 255.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1763)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 231, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 726)
[M::mem_pestat] mean and std.dev: (259.79, 135.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 917)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (351, 513, 1479)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3735)
[M::mem_pestat] mean and std.dev: (782.39, 866.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4863)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 335, 578)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1302)
[M::mem_pestat] mean and std.dev: (397.43, 282.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1664)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703512 sequences (100000227 bp) in 2.783 CPU sec, 3.303 real sec...
sorting block 78, #reads = 1078792 mem = 536875845 peak = 886116352
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (84, 285339, 50, 100)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 335, 1209)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3275)
[M::mem_pestat] mean and std.dev: (687.31, 790.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4308)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 234, 349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 739)
[M::mem_pestat] mean and std.dev: (263.26, 137.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 934)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 527, 1269)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3375)
[M::mem_pestat] mean and std.dev: (580.81, 566.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4428)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 303, 606)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1394)
[M::mem_pestat] mean and std.dev: (354.78, 256.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1788)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 705300 reads in 193.646 CPU sec, 6.357 real sec
[M::process] read 702994 sequences (100000272 bp) in 2.151 CPU sec, 2.212 real sec...
[M::mem_process_seqs] Processed 704424 reads in 132.236 CPU sec, 4.457 real sec
sorting block 79, #reads = 1079341 mem = 536879725 peak = 886116352
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (116, 284645, 37, 72)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 295, 465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1039)
[M::mem_pestat] mean and std.dev: (271.10, 135.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1326)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 236, 352)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 744)
[M::mem_pestat] mean and std.dev: (265.00, 138.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 940)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 768, 1762)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4960)
[M::mem_pestat] mean and std.dev: (898.06, 963.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6559)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 245, 469)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1051)
[M::mem_pestat] mean and std.dev: (309.03, 208.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1342)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702814 sequences (100000248 bp) in 3.237 CPU sec, 3.581 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (96, 284873, 38, 102)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 376, 1163)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3105)
[M::mem_pestat] mean and std.dev: (564.74, 545.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4076)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 237, 356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 756)
[M::mem_pestat] mean and std.dev: (267.10, 140.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 956)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (430, 995, 2733)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7339)
[M::mem_pestat] mean and std.dev: (1451.42, 1393.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9642)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 324, 483)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 991)
[M::mem_pestat] mean and std.dev: (298.15, 137.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1245)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702402 sequences (100000247 bp) in 2.008 CPU sec, 2.028 real sec...
[M::mem_process_seqs] Processed 703512 reads in 202.729 CPU sec, 6.694 real sec
[M::mem_process_seqs] Processed 702994 reads in 136.459 CPU sec, 4.401 real sec
sorting block 80, #reads = 1078640 mem = 536879567 peak = 886116352
[M::process] read 701986 sequences (100000256 bp) in 2.823 CPU sec, 3.210 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (114, 284479, 44, 123)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 271, 556)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1328)
[M::mem_pestat] mean and std.dev: (351.24, 280.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1714)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 240, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 764)
[M::mem_pestat] mean and std.dev: (270.16, 141.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 966)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (229, 847, 1670)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4552)
[M::mem_pestat] mean and std.dev: (708.78, 610.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5993)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (233, 339, 942)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2360)
[M::mem_pestat] mean and std.dev: (549.91, 547.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3069)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701114 sequences (100000071 bp) in 2.125 CPU sec, 2.257 real sec...
[M::mem_process_seqs] Processed 702402 reads in 117.531 CPU sec, 3.761 real sec
sorting block 81, #reads = 1076447 mem = 536880321 peak = 886116352
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (90, 284520, 39, 120)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 323, 818)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2124)
[M::mem_pestat] mean and std.dev: (448.04, 412.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2777)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 238, 356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 754)
[M::mem_pestat] mean and std.dev: (267.83, 140.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 953)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (93, 532, 2148)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6258)
[M::mem_pestat] mean and std.dev: (1208.11, 1663.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8313)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 297, 529)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1211)
[M::mem_pestat] mean and std.dev: (332.01, 240.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1552)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (110, 284300, 38, 124)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 297, 696)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1710)
[M::mem_pestat] mean and std.dev: (441.82, 407.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2217)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 242, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 765)
[M::mem_pestat] mean and std.dev: (271.51, 142.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 967)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (500, 1212, 2271)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5813)
[M::mem_pestat] mean and std.dev: (1371.14, 1161.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7584)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 384, 1015)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2611)
[M::mem_pestat] mean and std.dev: (604.83, 577.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3409)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702814 reads in 310.073 CPU sec, 9.999 real sec
[M::process] read 700690 sequences (100000072 bp) in 2.321 CPU sec, 2.382 real sec...
[M::mem_process_seqs] Processed 701986 reads in 159.339 CPU sec, 5.098 real sec
sorting block 82, #reads = 1076238 mem = 536879336 peak = 886116352
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (112, 284087, 51, 109)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 314, 454)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1008)
[M::mem_pestat] mean and std.dev: (331.70, 218.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1285)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 243, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 766)
[M::mem_pestat] mean and std.dev: (272.36, 142.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 968)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (680, 1206, 2211)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5273)
[M::mem_pestat] mean and std.dev: (1322.65, 967.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6804)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 316, 916)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2346)
[M::mem_pestat] mean and std.dev: (451.54, 410.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3061)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700392 sequences (100000189 bp) in 2.991 CPU sec, 3.355 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (110, 283569, 43, 121)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 312, 686)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1660)
[M::mem_pestat] mean and std.dev: (387.13, 318.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2147)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 245, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 767)
[M::mem_pestat] mean and std.dev: (273.15, 141.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 969)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (238, 846, 1393)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3703)
[M::mem_pestat] mean and std.dev: (739.32, 637.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4858)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 284, 937)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2471)
[M::mem_pestat] mean and std.dev: (462.41, 520.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3238)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701114 reads in 203.965 CPU sec, 6.833 real sec
[M::process] read 700708 sequences (100000093 bp) in 2.139 CPU sec, 2.280 real sec...
[M::mem_process_seqs] Processed 700690 reads in 141.217 CPU sec, 4.688 real sec
sorting block 83, #reads = 1074245 mem = 536885097 peak = 886116352
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (113, 283338, 44, 103)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 376, 1203)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3189)
[M::mem_pestat] mean and std.dev: (688.84, 733.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4182)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 244, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 764)
[M::mem_pestat] mean and std.dev: (272.75, 141.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 965)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (360, 792, 1329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3267)
[M::mem_pestat] mean and std.dev: (971.81, 836.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4317)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 299, 494)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1112)
[M::mem_pestat] mean and std.dev: (326.86, 203.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1421)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700812 sequences (100000065 bp) in 2.856 CPU sec, 3.263 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (138, 284135, 41, 106)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 358, 867)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2255)
[M::mem_pestat] mean and std.dev: (511.93, 491.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2949)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 242, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 757)
[M::mem_pestat] mean and std.dev: (270.83, 140.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 956)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (351, 802, 1728)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4482)
[M::mem_pestat] mean and std.dev: (834.15, 736.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5859)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 391, 694)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1694)
[M::mem_pestat] mean and std.dev: (424.37, 340.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2194)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700746 sequences (100000048 bp) in 2.173 CPU sec, 2.235 real sec...
[M::mem_process_seqs] Processed 700392 reads in 212.780 CPU sec, 7.072 real sec
sorting block 84, #reads = 1074101 mem = 536885596 peak = 886116352
[M::mem_process_seqs] Processed 700708 reads in 140.355 CPU sec, 4.695 real sec
sorting block 85, #reads = 1072307 mem = 536880669 peak = 886116352
[M::process] read 701238 sequences (100000112 bp) in 2.856 CPU sec, 3.242 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (84, 283086, 40, 114)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 343, 1152)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3106)
[M::mem_pestat] mean and std.dev: (547.79, 599.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4083)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 243, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 760)
[M::mem_pestat] mean and std.dev: (271.71, 141.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 960)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (562, 1063, 1993)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4855)
[M::mem_pestat] mean and std.dev: (1276.87, 960.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6286)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 351, 1175)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3169)
[M::mem_pestat] mean and std.dev: (515.64, 511.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4166)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705950 sequences (100000081 bp) in 2.107 CPU sec, 2.193 real sec...
[M::mem_process_seqs] Processed 700746 reads in 121.676 CPU sec, 3.903 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (101, 283086, 41, 86)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 430, 1339)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3587)
[M::mem_pestat] mean and std.dev: (737.09, 724.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4711)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 242, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 757)
[M::mem_pestat] mean and std.dev: (271.06, 140.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 956)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (465, 1171, 2733)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7269)
[M::mem_pestat] mean and std.dev: (1720.59, 1783.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9537)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 308, 465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1017)
[M::mem_pestat] mean and std.dev: (295.56, 149.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1293)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (98, 283753, 33, 108)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 320, 881)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2283)
[M::mem_pestat] mean and std.dev: (439.26, 372.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2984)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 242, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 757)
[M::mem_pestat] mean and std.dev: (270.73, 140.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 956)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (401, 856, 1952)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5054)
[M::mem_pestat] mean and std.dev: (1292.58, 1202.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6605)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 324, 695)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1669)
[M::mem_pestat] mean and std.dev: (387.19, 259.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2156)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700812 reads in 326.009 CPU sec, 10.575 real sec
[M::process] read 713708 sequences (100000169 bp) in 2.324 CPU sec, 2.422 real sec...
sorting block 86, #reads = 1072477 mem = 536878856 peak = 886116352
[M::process] read 711964 sequences (100000096 bp) in 2.347 CPU sec, 2.383 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (99, 284784, 40, 89)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 262, 700)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1790)
[M::mem_pestat] mean and std.dev: (397.41, 405.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2335)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 229, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 716)
[M::mem_pestat] mean and std.dev: (257.62, 135.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 904)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (240, 846, 1544)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4152)
[M::mem_pestat] mean and std.dev: (935.89, 863.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5456)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 264, 440)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 978)
[M::mem_pestat] mean and std.dev: (300.37, 198.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1247)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 705950 reads in 141.928 CPU sec, 4.856 real sec
sorting block 87, #reads = 1067617 mem = 536881206 peak = 886116352
[M::mem_process_seqs] Processed 701238 reads in 361.903 CPU sec, 11.973 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (88, 287999, 39, 87)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 297, 1101)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2887)
[M::mem_pestat] mean and std.dev: (523.42, 550.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3780)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (143, 211, 309)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 641)
[M::mem_pestat] mean and std.dev: (236.51, 121.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 807)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (312, 798, 1594)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4158)
[M::mem_pestat] mean and std.dev: (827.71, 731.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5440)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 292, 770)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1924)
[M::mem_pestat] mean and std.dev: (440.13, 415.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2501)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 709542 sequences (100000060 bp) in 2.988 CPU sec, 3.404 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (83, 286918, 29, 107)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 226, 498)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1158)
[M::mem_pestat] mean and std.dev: (264.23, 179.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1488)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 214, 315)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 655)
[M::mem_pestat] mean and std.dev: (240.65, 123.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 825)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (367, 798, 2706)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7384)
[M::mem_pestat] mean and std.dev: (1845.07, 2035.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9988)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 313, 609)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1415)
[M::mem_pestat] mean and std.dev: (342.57, 246.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1818)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 713708 reads in 262.618 CPU sec, 8.458 real sec
[M::process] read 707524 sequences (100000112 bp) in 2.155 CPU sec, 2.156 real sec...
sorting block 88, #reads = 1069944 mem = 536881315 peak = 886116352
[M::mem_process_seqs] Processed 711964 reads in 159.469 CPU sec, 5.187 real sec
sorting block 89, #reads = 1073494 mem = 536880740 peak = 886116352
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (120, 287126, 41, 97)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 293, 592)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1422)
[M::mem_pestat] mean and std.dev: (360.32, 275.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1837)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 221, 328)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 688)
[M::mem_pestat] mean and std.dev: (248.86, 129.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 868)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (602, 1803, 2443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6125)
[M::mem_pestat] mean and std.dev: (1408.34, 860.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7966)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 290, 1109)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2963)
[M::mem_pestat] mean and std.dev: (503.40, 634.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3890)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705926 sequences (100000009 bp) in 2.960 CPU sec, 3.564 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (115, 286334, 38, 109)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 273, 960)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2516)
[M::mem_pestat] mean and std.dev: (459.22, 462.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3294)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 225, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 699)
[M::mem_pestat] mean and std.dev: (253.31, 131.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 882)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (273, 1014, 1688)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4518)
[M::mem_pestat] mean and std.dev: (1027.76, 822.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5933)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 286, 869)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2205)
[M::mem_pestat] mean and std.dev: (488.37, 460.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2873)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705316 sequences (100000083 bp) in 2.184 CPU sec, 2.196 real sec...
[M::mem_process_seqs] Processed 709542 reads in 225.838 CPU sec, 7.355 real sec
[M::mem_process_seqs] Processed 707524 reads in 145.626 CPU sec, 4.651 real sec
sorting block 90, #reads = 1072757 mem = 536878839 peak = 886116352
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (113, 285130, 38, 117)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 414, 1069)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2821)
[M::mem_pestat] mean and std.dev: (603.21, 550.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3697)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 230, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 722)
[M::mem_pestat] mean and std.dev: (258.66, 134.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 912)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (427, 1128, 2193)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5725)
[M::mem_pestat] mean and std.dev: (1291.94, 1031.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7491)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 279, 460)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1044)
[M::mem_pestat] mean and std.dev: (285.01, 186.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1336)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703992 sequences (100000051 bp) in 3.004 CPU sec, 3.382 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (77, 285341, 32, 116)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 313, 633)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1511)
[M::mem_pestat] mean and std.dev: (340.97, 255.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1950)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 232, 346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 730)
[M::mem_pestat] mean and std.dev: (261.23, 136.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 922)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (286, 700, 1309)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3355)
[M::mem_pestat] mean and std.dev: (798.33, 802.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4378)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 302, 517)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1115)
[M::mem_pestat] mean and std.dev: (343.15, 221.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1414)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 703408 sequences (100000109 bp) in 2.010 CPU sec, 2.015 real sec...
[M::mem_process_seqs] Processed 705926 reads in 214.396 CPU sec, 6.944 real sec
[M::mem_process_seqs] Processed 705316 reads in 139.496 CPU sec, 4.508 real sec
sorting block 91, #reads = 1074150 mem = 536879764 peak = 886116352
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (115, 285012, 40, 123)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 293, 977)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2521)
[M::mem_pestat] mean and std.dev: (497.33, 491.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3293)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 236, 352)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 746)
[M::mem_pestat] mean and std.dev: (265.32, 139.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 943)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (47, 358, 2200)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6506)
[M::mem_pestat] mean and std.dev: (1194.38, 1538.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8659)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 304, 1020)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2642)
[M::mem_pestat] mean and std.dev: (603.37, 646.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3453)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702458 sequences (100000224 bp) in 3.203 CPU sec, 3.429 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (116, 284517, 50, 105)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 270, 494)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1128)
[M::mem_pestat] mean and std.dev: (310.86, 177.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1445)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 236, 353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 747)
[M::mem_pestat] mean and std.dev: (266.33, 139.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 944)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (233, 737, 1591)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4307)
[M::mem_pestat] mean and std.dev: (741.52, 727.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5665)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 445, 1616)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4484)
[M::mem_pestat] mean and std.dev: (785.48, 801.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5918)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702222 sequences (100000090 bp) in 2.036 CPU sec, 2.040 real sec...
[M::mem_process_seqs] Processed 703992 reads in 211.269 CPU sec, 6.798 real sec
sorting block 92, #reads = 1073349 mem = 536878963 peak = 886116352
[M::mem_process_seqs] Processed 703408 reads in 138.990 CPU sec, 4.507 real sec
sorting block 93, #reads = 1073679 mem = 536878239 peak = 886116352
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (97, 284200, 43, 125)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 320, 970)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2522)
[M::mem_pestat] mean and std.dev: (489.60, 501.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3298)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 238, 354)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 748)
[M::mem_pestat] mean and std.dev: (267.14, 139.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 945)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 888, 1778)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4950)
[M::mem_pestat] mean and std.dev: (945.67, 926.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6536)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 341, 704)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1688)
[M::mem_pestat] mean and std.dev: (409.82, 280.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2180)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702156 sequences (100000231 bp) in 2.952 CPU sec, 3.182 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (106, 284271, 39, 126)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 327, 1127)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3011)
[M::mem_pestat] mean and std.dev: (626.44, 705.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3953)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 238, 353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 743)
[M::mem_pestat] mean and std.dev: (267.13, 139.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 938)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (361, 507, 1350)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3328)
[M::mem_pestat] mean and std.dev: (680.82, 611.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4317)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 380, 638)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1488)
[M::mem_pestat] mean and std.dev: (379.84, 245.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1913)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702400 sequences (100000203 bp) in 2.084 CPU sec, 2.086 real sec...
[M::mem_process_seqs] Processed 702458 reads in 215.044 CPU sec, 6.967 real sec
[M::mem_process_seqs] Processed 702222 reads in 139.122 CPU sec, 4.481 real sec
sorting block 94, #reads = 1071682 mem = 536878977 peak = 886116352
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (114, 283283, 55, 119)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 317, 925)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2407)
[M::mem_pestat] mean and std.dev: (444.91, 409.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3148)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 238, 353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 743)
[M::mem_pestat] mean and std.dev: (267.14, 139.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 938)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (471, 996, 2862)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7644)
[M::mem_pestat] mean and std.dev: (1554.71, 1737.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10035)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 332, 885)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2267)
[M::mem_pestat] mean and std.dev: (472.02, 423.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2958)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701784 sequences (100000142 bp) in 3.076 CPU sec, 3.267 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (111, 284084, 37, 95)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 318, 855)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2145)
[M::mem_pestat] mean and std.dev: (476.00, 443.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2790)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 238, 354)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 746)
[M::mem_pestat] mean and std.dev: (267.37, 139.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 942)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (233, 594, 1517)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4085)
[M::mem_pestat] mean and std.dev: (889.42, 852.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5369)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 351, 672)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1620)
[M::mem_pestat] mean and std.dev: (423.11, 307.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2094)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701504 sequences (100000202 bp) in 2.060 CPU sec, 2.069 real sec...
[M::mem_process_seqs] Processed 702156 reads in 209.815 CPU sec, 6.739 real sec
[M::mem_process_seqs] Processed 702400 reads in 138.481 CPU sec, 4.401 real sec
sorting block 95, #reads = 1073354 mem = 536881871 peak = 886116352
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (90, 284016, 44, 110)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 283, 450)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1018)
[M::mem_pestat] mean and std.dev: (310.14, 221.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1302)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 240, 356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 750)
[M::mem_pestat] mean and std.dev: (268.79, 140.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 947)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 702, 2531)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7213)
[M::mem_pestat] mean and std.dev: (1130.59, 1511.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9554)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 302, 578)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1326)
[M::mem_pestat] mean and std.dev: (347.19, 221.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1700)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701534 sequences (100000121 bp) in 3.055 CPU sec, 3.286 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (119, 283553, 57, 115)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 309, 1315)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3571)
[M::mem_pestat] mean and std.dev: (716.72, 847.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4699)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 240, 357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 753)
[M::mem_pestat] mean and std.dev: (269.27, 140.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 951)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (276, 1402, 2212)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6084)
[M::mem_pestat] mean and std.dev: (1268.85, 1050.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8020)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 276, 959)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2487)
[M::mem_pestat] mean and std.dev: (484.66, 556.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3251)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700550 sequences (100000161 bp) in 2.070 CPU sec, 2.072 real sec...
[M::mem_process_seqs] Processed 701784 reads in 203.658 CPU sec, 6.599 real sec
sorting block 96, #reads = 1073664 mem = 536881163 peak = 886116352
[M::mem_process_seqs] Processed 701504 reads in 136.848 CPU sec, 4.349 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (101, 284027, 48, 113)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 313, 432)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 948)
[M::mem_pestat] mean and std.dev: (300.77, 164.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1206)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 241, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 756)
[M::mem_pestat] mean and std.dev: (269.96, 141.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 955)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (349, 1101, 2829)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7789)
[M::mem_pestat] mean and std.dev: (1618.73, 1579.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10269)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 401, 985)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2513)
[M::mem_pestat] mean and std.dev: (589.71, 574.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3277)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 97, #reads = 1075121 mem = 536881864 peak = 886116352
[M::process] read 700554 sequences (100000283 bp) in 2.993 CPU sec, 3.323 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (73, 283611, 47, 97)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 290, 1001)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2663)
[M::mem_pestat] mean and std.dev: (461.44, 488.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3494)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 243, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 763)
[M::mem_pestat] mean and std.dev: (272.35, 142.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 964)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (432, 883, 1675)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4161)
[M::mem_pestat] mean and std.dev: (1012.40, 997.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5404)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 335, 756)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1850)
[M::mem_pestat] mean and std.dev: (421.33, 338.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2397)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 285304 sequences (40654165 bp) in 1.531 CPU sec, 1.544 real sec...
[M::mem_process_seqs] Processed 701534 reads in 199.173 CPU sec, 6.384 real sec
[M::mem_process_seqs] Processed 700550 reads in 136.050 CPU sec, 4.484 real sec
sorting block 98, #reads = 1075373 mem = 536878819 peak = 886116352
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (119, 283787, 49, 102)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 352, 737)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1831)
[M::mem_pestat] mean and std.dev: (391.31, 307.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2378)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 244, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 764)
[M::mem_pestat] mean and std.dev: (273.27, 143.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 965)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (311, 932, 3704)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10490)
[M::mem_pestat] mean and std.dev: (2137.29, 2194.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13883)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 361, 654)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1550)
[M::mem_pestat] mean and std.dev: (408.22, 295.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1998)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 115350, 12, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 402, 716)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1700)
[M::mem_pestat] mean and std.dev: (478.51, 293.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2192)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 240, 357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 755)
[M::mem_pestat] mean and std.dev: (269.13, 140.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 954)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1451, 1814, 3311)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7031)
[M::mem_pestat] mean and std.dev: (1766.09, 1033.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8891)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (252, 357, 702)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1602)
[M::mem_pestat] mean and std.dev: (318.00, 147.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2052)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700554 reads in 151.103 CPU sec, 5.076 real sec
[M::mem_process_seqs] Processed 285304 reads in 70.031 CPU sec, 2.266 real sec
sorting block 99, #reads = 1074906 mem = 536880853 peak = 886116352
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000a06d1
  features: 1f8bfbff fffab20b
  extended: f1bf27eb 1b407f7e
  amd bits: 2c100800 00000121
     brand: Intel(R) Xeon(R) 6975P-C
threads: 31
algo: bwa-mem
license: sentieon:klib=31
reads: 106997020
overall: 69721903104 mem 18483.954 user 590.490 sys 631.848 real
[main] Version: 0.7.17-r1188
[main] CMD: /opt/conda/share/sentieon-202308.03-3/libexec/bwa mem -K 100000000 -Y -R @RG\tID:A23MHWWLT4.1136_85O-T1-TDNA-1_A23MHWWLT4_1.L003\tPU:L003\tSM:1136_85O-T1-TDNA-1_A23MHWWLT4_1\tLB:1136_85O-T1-TDNA-1_A23MHWWLT4_1\tDS:s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta\tPL:ILLUMINA -t 31 ./BWAIndex/Homo_sapiens_assembly38.fasta.64 1136_85O-T1-TDNA-1_A23MHWWLT4_1_R1.fastq.gz 1136_85O-T1-TDNA-1_A23MHWWLT4_1_R2.fastq.gz
[main] Real time: 631.897 sec; CPU: 19074.463 sec
sorting block 100, #reads = 533906 mem = 267019769 peak = 886116352
uniq header count 1
merging 101 blocks
sw version: sentieon-genomics-202308.03
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000a06d1
  features: 1f8bfbff fffab20b
  extended: f1bf27eb 1b407f7e
  amd bits: 2c100800 00000121
     brand: Intel(R) Xeon(R) 6975P-C
threads: 31 max 384
algo: util-sort
license: sentieon:util=1
output file size: 6081955432
output reads: 108142646
bam_mem_sort: 101 calls 91.122 user 1.839 sys 94.267 real
bam_write: 101 calls 74.042 user 6.342 sys 133.136 real
execute: 1 calls 37.516 user 2.419 sys 675.816 real
merge_files: 1 calls 37.495 user 2.392 sys 43.509 real
parse_chunk: 1608 calls 77.069 user 22.596 sys 118.465 real
read_chunk: 4352 calls 53.589 user 22.594 sys 568.395 real
sort_block: 1 calls 38.769 user 21.436 sys 547.387 real
write_chunk: 2742 calls 36.829 user 1.997 sys 42.046 real
overall: 2946727936 mem 1682.224 user 86.067 sys 675.833 real
ls: cannot access '*.cram': No such file or directory