cmdline: /opt/conda/share/sentieon-202308.03-3/libexec/util sort -r Homo_sapiens_assembly38.fasta -t 31 -o 1136_5TB-T1-TDNA-1_A23MHWWLT4_1.bam --sam2bam -
This software is licensed to bgold@natera.com by Sentieon Inc.
This software is licensed to bgold@natera.com by Sentieon Inc.
version: sentieon-genomics-202308.03
[M::bwa_idx_load_from_disk] read 3171 ALT contigs
[M::main_mem] bwa index loaded in 1844.659 CPU sec, 66.639 real sec
[M::process] read 699982 sequences (100000201 bp) in 1.095 CPU sec, 1.096 real sec...
[M::process] read 698764 sequences (100000297 bp) in 1.403 CPU sec, 1.486 real sec...
[M::process] read 697112 sequences (100000130 bp) in 1.378 CPU sec, 1.377 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 286405, 25, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (143, 247, 835)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2219)
[M::mem_pestat] mean and std.dev: (397.40, 396.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2911)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 239, 346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 720)
[M::mem_pestat] mean and std.dev: (263.24, 131.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 907)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 514, 1514)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4126)
[M::mem_pestat] mean and std.dev: (908.28, 848.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5432)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 261, 377)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 773)
[M::mem_pestat] mean and std.dev: (247.75, 122.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 971)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695920 sequences (100000141 bp) in 1.309 CPU sec, 1.307 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 285716, 18, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 211, 893)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2383)
[M::mem_pestat] mean and std.dev: (468.41, 558.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3128)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 247, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 746)
[M::mem_pestat] mean and std.dev: (271.76, 135.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 940)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 769, 865)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2193)
[M::mem_pestat] mean and std.dev: (544.31, 380.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2857)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (243, 346, 538)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1128)
[M::mem_pestat] mean and std.dev: (323.80, 134.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1423)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 285705, 16, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 300, 807)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2035)
[M::mem_pestat] mean and std.dev: (429.26, 365.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2649)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 241, 349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 725)
[M::mem_pestat] mean and std.dev: (265.81, 132.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 913)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (143, 409, 1189)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3281)
[M::mem_pestat] mean and std.dev: (346.23, 332.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4327)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 376, 775)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1903)
[M::mem_pestat] mean and std.dev: (489.44, 382.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2467)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699982 reads in 270.153 CPU sec, 8.697 real sec
[M::mem_process_seqs] Processed 697112 reads in 181.781 CPU sec, 5.906 real sec
[M::mem_process_seqs] Processed 698764 reads in 198.561 CPU sec, 6.469 real sec
sorting block 0, #reads = 1084516 mem = 536879801 peak = 587829248
[M::process] read 695792 sequences (100000079 bp) in 2.065 CPU sec, 2.266 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 285002, 11, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 237, 472)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1050)
[M::mem_pestat] mean and std.dev: (287.00, 187.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1339)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 250, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 763)
[M::mem_pestat] mean and std.dev: (275.98, 138.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 962)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (418, 516, 835)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1669)
[M::mem_pestat] mean and std.dev: (577.30, 289.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2086)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 335, 509)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1091)
[M::mem_pestat] mean and std.dev: (350.04, 206.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1382)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695148 sequences (100000040 bp) in 1.476 CPU sec, 1.510 real sec...
[M::process] read 695052 sequences (100000105 bp) in 1.170 CPU sec, 1.167 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 284851, 20, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 214, 459)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1051)
[M::mem_pestat] mean and std.dev: (259.82, 141.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1347)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 251, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 755)
[M::mem_pestat] mean and std.dev: (275.80, 137.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 951)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (508, 830, 2267)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5785)
[M::mem_pestat] mean and std.dev: (1062.78, 1120.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7544)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (246, 380, 787)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1869)
[M::mem_pestat] mean and std.dev: (408.50, 277.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2410)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695920 reads in 163.812 CPU sec, 5.226 real sec
sorting block 1, #reads = 1084463 mem = 536878425 peak = 835219456
[M::mem_process_seqs] Processed 695792 reads in 103.815 CPU sec, 3.300 real sec
sorting block 2, #reads = 1083277 mem = 536880665 peak = 860782592
[M::process] read 694376 sequences (100000107 bp) in 1.641 CPU sec, 1.773 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 284789, 23, 73)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 327, 826)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2116)
[M::mem_pestat] mean and std.dev: (559.47, 534.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2761)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 250, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 752)
[M::mem_pestat] mean and std.dev: (275.16, 136.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 947)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 524, 929)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2431)
[M::mem_pestat] mean and std.dev: (510.90, 499.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3182)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 330, 857)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2189)
[M::mem_pestat] mean and std.dev: (368.28, 306.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2855)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 693598 sequences (100000227 bp) in 1.310 CPU sec, 1.302 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 284743, 20, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 252, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 640)
[M::mem_pestat] mean and std.dev: (256.91, 118.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 792)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 250, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 750)
[M::mem_pestat] mean and std.dev: (275.26, 136.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 944)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (145, 574, 1008)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2734)
[M::mem_pestat] mean and std.dev: (658.30, 635.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3597)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 262, 465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1023)
[M::mem_pestat] mean and std.dev: (257.87, 116.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1302)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 284701, 19, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 324, 1060)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2780)
[M::mem_pestat] mean and std.dev: (580.07, 576.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3640)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 253, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 757)
[M::mem_pestat] mean and std.dev: (277.68, 137.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 953)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 947, 1242)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3410)
[M::mem_pestat] mean and std.dev: (889.05, 810.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4494)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 310, 709)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1771)
[M::mem_pestat] mean and std.dev: (318.74, 219.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2302)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695148 reads in 232.715 CPU sec, 7.614 real sec
[M::mem_process_seqs] Processed 695052 reads in 168.613 CPU sec, 5.448 real sec
[M::mem_process_seqs] Processed 694376 reads in 183.591 CPU sec, 5.956 real sec
sorting block 3, #reads = 1083154 mem = 536879384 peak = 860782592
[M::process] read 692576 sequences (100000128 bp) in 2.297 CPU sec, 2.510 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 284312, 22, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (215, 337, 671)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1583)
[M::mem_pestat] mean and std.dev: (429.35, 330.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2039)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 256, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 759)
[M::mem_pestat] mean and std.dev: (279.29, 136.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 955)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (511, 621, 1726)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4156)
[M::mem_pestat] mean and std.dev: (963.77, 834.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5371)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (263, 321, 467)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 875)
[M::mem_pestat] mean and std.dev: (320.69, 150.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1079)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 4, #reads = 1082201 mem = 536878767 peak = 860782592
[M::process] read 694914 sequences (100000210 bp) in 1.742 CPU sec, 1.864 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 284051, 17, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 296, 1084)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2868)
[M::mem_pestat] mean and std.dev: (513.34, 521.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3760)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 261, 372)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 770)
[M::mem_pestat] mean and std.dev: (283.19, 138.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 969)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (63, 507, 1127)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3255)
[M::mem_pestat] mean and std.dev: (541.25, 482.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4319)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 319, 470)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1020)
[M::mem_pestat] mean and std.dev: (339.77, 186.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1295)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 693598 reads in 165.582 CPU sec, 5.448 real sec
[M::process] read 700066 sequences (100000175 bp) in 1.389 CPU sec, 1.424 real sec...
[M::mem_process_seqs] Processed 692576 reads in 109.125 CPU sec, 3.461 real sec
sorting block 5, #reads = 1081377 mem = 536879989 peak = 860782592
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 284551, 26, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 252, 468)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1032)
[M::mem_pestat] mean and std.dev: (286.85, 180.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1314)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 254, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 762)
[M::mem_pestat] mean and std.dev: (277.68, 137.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 960)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 707, 1297)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3499)
[M::mem_pestat] mean and std.dev: (778.77, 629.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4600)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 284, 449)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1015)
[M::mem_pestat] mean and std.dev: (282.00, 160.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1298)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698372 sequences (100000054 bp) in 2.249 CPU sec, 2.428 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 286550, 19, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 267, 391)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 849)
[M::mem_pestat] mean and std.dev: (287.80, 180.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1078)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 240, 351)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 733)
[M::mem_pestat] mean and std.dev: (265.47, 133.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 924)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 468, 2009)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5607)
[M::mem_pestat] mean and std.dev: (1201.22, 1335.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7406)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 274, 505)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1175)
[M::mem_pestat] mean and std.dev: (287.20, 203.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1510)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697264 sequences (100000198 bp) in 1.752 CPU sec, 1.762 real sec...
[M::mem_process_seqs] Processed 694914 reads in 165.263 CPU sec, 5.273 real sec
[M::mem_process_seqs] Processed 700066 reads in 105.647 CPU sec, 3.576 real sec
sorting block 6, #reads = 1081050 mem = 536878196 peak = 860782592
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 285900, 23, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 200, 747)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1923)
[M::mem_pestat] mean and std.dev: (429.21, 387.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2511)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 244, 356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 744)
[M::mem_pestat] mean and std.dev: (269.48, 135.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 938)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (645, 2469, 5304)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 14622)
[M::mem_pestat] mean and std.dev: (3448.61, 3187.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 19281)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 323, 677)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1651)
[M::mem_pestat] mean and std.dev: (369.90, 242.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2138)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696424 sequences (100000017 bp) in 2.354 CPU sec, 2.515 real sec...
[M::process] read 695732 sequences (100000186 bp) in 1.810 CPU sec, 1.811 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 285897, 19, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (146, 232, 306)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 626)
[M::mem_pestat] mean and std.dev: (190.57, 61.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 786)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 248, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 755)
[M::mem_pestat] mean and std.dev: (273.16, 137.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 952)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (102, 430, 1087)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3057)
[M::mem_pestat] mean and std.dev: (627.41, 628.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4042)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 396, 721)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1779)
[M::mem_pestat] mean and std.dev: (434.64, 315.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2308)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 698372 reads in 172.153 CPU sec, 5.719 real sec
sorting block 7, #reads = 1086942 mem = 536879095 peak = 860782592
[M::mem_process_seqs] Processed 697264 reads in 108.045 CPU sec, 3.450 real sec
sorting block 8, #reads = 1085287 mem = 536878511 peak = 860782592
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 286028, 15, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (145, 306, 1030)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2800)
[M::mem_pestat] mean and std.dev: (518.89, 599.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3685)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 251, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 769)
[M::mem_pestat] mean and std.dev: (276.93, 139.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 970)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (514, 872, 1185)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2527)
[M::mem_pestat] mean and std.dev: (975.00, 789.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4132)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 274, 482)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1132)
[M::mem_pestat] mean and std.dev: (317.66, 202.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1457)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695958 sequences (100000179 bp) in 2.383 CPU sec, 2.502 real sec...
[M::process] read 695510 sequences (100000182 bp) in 1.710 CPU sec, 1.709 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 285045, 19, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 299, 464)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1078)
[M::mem_pestat] mean and std.dev: (270.09, 148.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1385)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 252, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 767)
[M::mem_pestat] mean and std.dev: (277.66, 139.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 967)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (82, 651, 2010)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5866)
[M::mem_pestat] mean and std.dev: (912.53, 895.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7794)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 311, 457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 969)
[M::mem_pestat] mean and std.dev: (320.06, 147.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1225)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696424 reads in 167.018 CPU sec, 5.324 real sec
[M::mem_process_seqs] Processed 695732 reads in 109.412 CPU sec, 3.475 real sec
sorting block 9, #reads = 1084981 mem = 536877948 peak = 860782592
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 284770, 29, 80)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 347, 520)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1230)
[M::mem_pestat] mean and std.dev: (428.35, 317.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1696)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 249, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 751)
[M::mem_pestat] mean and std.dev: (274.14, 136.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 946)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (525, 1808, 2709)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7077)
[M::mem_pestat] mean and std.dev: (1734.75, 1414.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9261)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 264, 472)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1028)
[M::mem_pestat] mean and std.dev: (320.93, 197.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1306)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694734 sequences (100000196 bp) in 2.351 CPU sec, 2.511 real sec...
[M::process] read 694032 sequences (100000282 bp) in 1.830 CPU sec, 1.832 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 284779, 14, 62)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 341, 1320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3588)
[M::mem_pestat] mean and std.dev: (760.08, 867.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4722)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 250, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 740)
[M::mem_pestat] mean and std.dev: (272.98, 134.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 931)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (445, 621, 895)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1795)
[M::mem_pestat] mean and std.dev: (587.17, 248.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2245)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 295, 559)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1299)
[M::mem_pestat] mean and std.dev: (308.11, 176.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1669)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695958 reads in 168.676 CPU sec, 5.466 real sec
[M::mem_process_seqs] Processed 695510 reads in 108.455 CPU sec, 3.445 real sec
sorting block 10, #reads = 1082779 mem = 536888331 peak = 860782592
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 284524, 19, 53)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 346, 864)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2206)
[M::mem_pestat] mean and std.dev: (568.07, 517.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2877)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 252, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 750)
[M::mem_pestat] mean and std.dev: (275.30, 135.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 944)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (489, 686, 925)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1797)
[M::mem_pestat] mean and std.dev: (655.00, 300.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2233)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 298, 510)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1148)
[M::mem_pestat] mean and std.dev: (339.46, 250.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1467)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 693420 sequences (100000295 bp) in 2.426 CPU sec, 2.540 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 284584, 21, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (137, 200, 512)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1262)
[M::mem_pestat] mean and std.dev: (241.46, 185.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1637)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 255, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 761)
[M::mem_pestat] mean and std.dev: (278.89, 137.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 958)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (81, 843, 2161)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6321)
[M::mem_pestat] mean and std.dev: (787.47, 771.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8401)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 310, 437)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 867)
[M::mem_pestat] mean and std.dev: (302.32, 120.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1082)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698748 sequences (100000053 bp) in 1.850 CPU sec, 1.853 real sec...
[M::mem_process_seqs] Processed 694734 reads in 159.571 CPU sec, 5.050 real sec
[M::mem_process_seqs] Processed 694032 reads in 102.881 CPU sec, 3.255 real sec
sorting block 11, #reads = 1082112 mem = 536877420 peak = 860782592
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 284642, 21, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 304, 870)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2168)
[M::mem_pestat] mean and std.dev: (529.40, 468.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2817)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 257, 370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 768)
[M::mem_pestat] mean and std.dev: (281.06, 139.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 967)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (252, 762, 1420)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3756)
[M::mem_pestat] mean and std.dev: (744.05, 690.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4924)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (250, 317, 462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 886)
[M::mem_pestat] mean and std.dev: (338.26, 156.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1098)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700770 sequences (100000097 bp) in 2.324 CPU sec, 2.442 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 285837, 22, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 204, 354)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 762)
[M::mem_pestat] mean and std.dev: (239.27, 134.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 966)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 243, 354)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 740)
[M::mem_pestat] mean and std.dev: (268.35, 135.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 933)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (302, 550, 1104)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2708)
[M::mem_pestat] mean and std.dev: (776.90, 750.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3780)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (234, 317, 668)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1536)
[M::mem_pestat] mean and std.dev: (436.27, 337.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1970)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 698640 sequences (100000162 bp) in 1.830 CPU sec, 1.824 real sec...
[M::mem_process_seqs] Processed 693420 reads in 159.304 CPU sec, 5.052 real sec
sorting block 12, #reads = 1081816 mem = 536879976 peak = 860782592
[M::mem_process_seqs] Processed 698748 reads in 104.655 CPU sec, 3.313 real sec
sorting block 13, #reads = 1081234 mem = 536881352 peak = 910016512
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 286811, 24, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 269, 434)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 988)
[M::mem_pestat] mean and std.dev: (269.38, 190.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1265)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 237, 347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 725)
[M::mem_pestat] mean and std.dev: (262.66, 131.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 914)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (242, 995, 1501)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4019)
[M::mem_pestat] mean and std.dev: (886.96, 714.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5278)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 316, 604)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1380)
[M::mem_pestat] mean and std.dev: (391.92, 236.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1768)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697250 sequences (100000245 bp) in 2.439 CPU sec, 2.599 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 286259, 22, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 334, 701)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1721)
[M::mem_pestat] mean and std.dev: (392.50, 259.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2231)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 243, 353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 735)
[M::mem_pestat] mean and std.dev: (267.62, 132.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 926)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (870, 1600, 2367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5361)
[M::mem_pestat] mean and std.dev: (1246.65, 849.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6858)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (234, 354, 497)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1023)
[M::mem_pestat] mean and std.dev: (371.15, 232.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1303)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696084 sequences (100000129 bp) in 1.830 CPU sec, 1.834 real sec...
[M::mem_process_seqs] Processed 700770 reads in 156.210 CPU sec, 4.949 real sec
[M::mem_process_seqs] Processed 698640 reads in 101.876 CPU sec, 3.221 real sec
sorting block 14, #reads = 1085709 mem = 536878530 peak = 910016512
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 285837, 17, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (212, 404, 1068)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2780)
[M::mem_pestat] mean and std.dev: (505.21, 595.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3636)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 248, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 752)
[M::mem_pestat] mean and std.dev: (272.63, 135.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 948)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (367, 1395, 3158)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8740)
[M::mem_pestat] mean and std.dev: (1971.18, 1733.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11531)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 397, 701)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1649)
[M::mem_pestat] mean and std.dev: (375.14, 242.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2123)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695434 sequences (100000138 bp) in 2.372 CPU sec, 2.493 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 285078, 16, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 260, 759)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1981)
[M::mem_pestat] mean and std.dev: (480.37, 536.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2627)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 251, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 757)
[M::mem_pestat] mean and std.dev: (275.26, 136.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 954)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (319, 671, 1563)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4051)
[M::mem_pestat] mean and std.dev: (915.80, 841.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5295)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 289, 706)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1768)
[M::mem_pestat] mean and std.dev: (373.06, 285.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2299)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697250 reads in 154.615 CPU sec, 4.911 real sec
[M::process] read 695310 sequences (100000139 bp) in 1.904 CPU sec, 1.903 real sec...
[M::mem_process_seqs] Processed 696084 reads in 102.793 CPU sec, 3.242 real sec
sorting block 15, #reads = 1084505 mem = 536886268 peak = 910016512
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 284376, 15, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 253, 485)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1103)
[M::mem_pestat] mean and std.dev: (330.50, 243.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1412)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 252, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 758)
[M::mem_pestat] mean and std.dev: (275.92, 136.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 955)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (380, 1153, 1431)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3533)
[M::mem_pestat] mean and std.dev: (925.60, 566.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4584)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (225, 252, 356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 618)
[M::mem_pestat] mean and std.dev: (255.42, 94.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 749)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694960 sequences (100000232 bp) in 2.401 CPU sec, 2.513 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 285166, 16, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 397, 810)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2080)
[M::mem_pestat] mean and std.dev: (415.80, 382.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2715)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 250, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 746)
[M::mem_pestat] mean and std.dev: (273.92, 134.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 939)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (292, 323, 686)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1474)
[M::mem_pestat] mean and std.dev: (409.71, 308.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1868)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 292, 455)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1009)
[M::mem_pestat] mean and std.dev: (290.45, 168.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1286)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694232 sequences (100000107 bp) in 1.840 CPU sec, 1.842 real sec...
[M::mem_process_seqs] Processed 695434 reads in 159.869 CPU sec, 5.070 real sec
sorting block 16, #reads = 1083324 mem = 536878993 peak = 910016512
[M::mem_process_seqs] Processed 695310 reads in 104.731 CPU sec, 3.307 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 284797, 28, 66)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 350, 662)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1592)
[M::mem_pestat] mean and std.dev: (341.53, 211.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2057)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 252, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 750)
[M::mem_pestat] mean and std.dev: (275.71, 136.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 944)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (386, 635, 898)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1922)
[M::mem_pestat] mean and std.dev: (652.00, 401.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2434)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 286, 607)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1473)
[M::mem_pestat] mean and std.dev: (366.73, 278.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1906)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 17, #reads = 1082260 mem = 536877855 peak = 910016512
[M::process] read 694282 sequences (100000226 bp) in 2.497 CPU sec, 2.667 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 284334, 21, 65)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 265, 546)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1322)
[M::mem_pestat] mean and std.dev: (306.09, 245.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1710)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 252, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 748)
[M::mem_pestat] mean and std.dev: (275.90, 135.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 941)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (273, 393, 1832)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4950)
[M::mem_pestat] mean and std.dev: (695.11, 763.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6509)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 276, 465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1017)
[M::mem_pestat] mean and std.dev: (243.15, 104.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1293)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695000 sequences (100000247 bp) in 1.450 CPU sec, 1.452 real sec...
[M::mem_process_seqs] Processed 694960 reads in 163.670 CPU sec, 5.206 real sec
[M::mem_process_seqs] Processed 694232 reads in 106.473 CPU sec, 3.376 real sec
sorting block 18, #reads = 1081341 mem = 536878468 peak = 910016512
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 284690, 20, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 257, 433)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 915)
[M::mem_pestat] mean and std.dev: (297.74, 186.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1156)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 254, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 760)
[M::mem_pestat] mean and std.dev: (278.29, 138.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 957)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (801, 1119, 1743)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3627)
[M::mem_pestat] mean and std.dev: (1090.61, 692.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4569)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 291, 410)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 860)
[M::mem_pestat] mean and std.dev: (283.26, 151.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1085)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700596 sequences (100000102 bp) in 2.545 CPU sec, 2.690 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (77, 284971, 13, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 327, 513)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1157)
[M::mem_pestat] mean and std.dev: (323.69, 199.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1479)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 251, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 753)
[M::mem_pestat] mean and std.dev: (275.68, 136.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 948)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (461, 861, 2981)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8021)
[M::mem_pestat] mean and std.dev: (1029.83, 964.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10541)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 268, 716)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1738)
[M::mem_pestat] mean and std.dev: (419.89, 382.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2249)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699006 sequences (100000183 bp) in 1.790 CPU sec, 1.784 real sec...
[M::mem_process_seqs] Processed 694282 reads in 163.714 CPU sec, 5.191 real sec
[M::mem_process_seqs] Processed 695000 reads in 107.683 CPU sec, 3.404 real sec
sorting block 19, #reads = 1080786 mem = 536878436 peak = 910016512
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 287211, 22, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 215, 393)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 847)
[M::mem_pestat] mean and std.dev: (245.02, 131.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1074)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 238, 347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 725)
[M::mem_pestat] mean and std.dev: (263.52, 132.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 914)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 799, 1254)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3416)
[M::mem_pestat] mean and std.dev: (751.76, 690.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4497)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 260, 913)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2379)
[M::mem_pestat] mean and std.dev: (492.67, 547.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3112)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697962 sequences (100000084 bp) in 2.457 CPU sec, 2.582 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 286261, 22, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 225, 525)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1277)
[M::mem_pestat] mean and std.dev: (261.61, 202.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1653)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 242, 353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 737)
[M::mem_pestat] mean and std.dev: (267.21, 133.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 929)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (45, 674, 767)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2211)
[M::mem_pestat] mean and std.dev: (440.58, 506.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2933)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (269, 376, 678)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1496)
[M::mem_pestat] mean and std.dev: (379.09, 247.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1905)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697180 sequences (100000062 bp) in 1.780 CPU sec, 1.778 real sec...
[M::mem_process_seqs] Processed 700596 reads in 158.780 CPU sec, 5.039 real sec
sorting block 20, #reads = 1082414 mem = 536879832 peak = 910016512
[M::mem_process_seqs] Processed 699006 reads in 112.811 CPU sec, 3.598 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 285550, 28, 81)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (245, 314, 1030)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2600)
[M::mem_pestat] mean and std.dev: (613.60, 697.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3405)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 246, 357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 745)
[M::mem_pestat] mean and std.dev: (270.43, 135.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 939)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (469, 1074, 2425)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6337)
[M::mem_pestat] mean and std.dev: (1459.50, 1259.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8293)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 306, 751)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1875)
[M::mem_pestat] mean and std.dev: (395.11, 337.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2437)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696466 sequences (100000003 bp) in 2.435 CPU sec, 2.582 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 286005, 18, 72)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (133, 322, 454)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1096)
[M::mem_pestat] mean and std.dev: (279.29, 146.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1417)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 250, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 753)
[M::mem_pestat] mean and std.dev: (273.78, 136.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 949)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (243, 629, 1331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3507)
[M::mem_pestat] mean and std.dev: (615.80, 470.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4595)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 330, 715)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1715)
[M::mem_pestat] mean and std.dev: (356.40, 225.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2215)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697138 sequences (100000053 bp) in 1.540 CPU sec, 1.542 real sec...
[M::mem_process_seqs] Processed 697962 reads in 161.218 CPU sec, 5.135 real sec
sorting block 21, #reads = 1085969 mem = 536878711 peak = 910016512
[M::mem_process_seqs] Processed 697180 reads in 104.475 CPU sec, 3.310 real sec
sorting block 22, #reads = 1084146 mem = 536880089 peak = 910016512
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 284946, 22, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 275, 346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 636)
[M::mem_pestat] mean and std.dev: (274.62, 112.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 781)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 251, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 757)
[M::mem_pestat] mean and std.dev: (275.35, 137.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 954)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 431, 962)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2472)
[M::mem_pestat] mean and std.dev: (646.73, 616.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3227)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 266, 429)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 909)
[M::mem_pestat] mean and std.dev: (307.21, 157.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1149)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695824 sequences (100000172 bp) in 2.789 CPU sec, 2.914 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 285309, 23, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (136, 239, 416)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 976)
[M::mem_pestat] mean and std.dev: (276.33, 200.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1256)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 245, 356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 740)
[M::mem_pestat] mean and std.dev: (270.28, 134.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 932)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (501, 664, 1562)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3684)
[M::mem_pestat] mean and std.dev: (965.13, 650.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4745)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 311, 844)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2162)
[M::mem_pestat] mean and std.dev: (430.34, 381.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2821)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695092 sequences (100000295 bp) in 1.829 CPU sec, 1.828 real sec...
[M::mem_process_seqs] Processed 696466 reads in 162.627 CPU sec, 5.161 real sec
[M::mem_process_seqs] Processed 697138 reads in 105.757 CPU sec, 3.350 real sec
sorting block 23, #reads = 1084034 mem = 536884210 peak = 910016512
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 285563, 22, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 383, 649)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1515)
[M::mem_pestat] mean and std.dev: (442.91, 321.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1948)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 248, 357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 739)
[M::mem_pestat] mean and std.dev: (271.74, 133.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 930)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (282, 890, 2587)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7197)
[M::mem_pestat] mean and std.dev: (1953.18, 2033.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10086)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 333, 1018)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2680)
[M::mem_pestat] mean and std.dev: (402.75, 367.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3511)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694368 sequences (100000115 bp) in 2.513 CPU sec, 2.668 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 284671, 18, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 299, 523)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1221)
[M::mem_pestat] mean and std.dev: (300.86, 191.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1570)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 249, 356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 734)
[M::mem_pestat] mean and std.dev: (271.71, 132.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 923)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 891, 1040)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2758)
[M::mem_pestat] mean and std.dev: (587.33, 402.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3617)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 300, 411)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 833)
[M::mem_pestat] mean and std.dev: (312.37, 135.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1044)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694102 sequences (100000133 bp) in 1.430 CPU sec, 1.423 real sec...
[M::mem_process_seqs] Processed 695824 reads in 168.515 CPU sec, 5.392 real sec
[M::mem_process_seqs] Processed 695092 reads in 106.330 CPU sec, 3.369 real sec
sorting block 24, #reads = 1082596 mem = 536884247 peak = 910016512
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 284802, 32, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 296, 967)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2547)
[M::mem_pestat] mean and std.dev: (576.00, 641.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3337)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 251, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 736)
[M::mem_pestat] mean and std.dev: (273.02, 132.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 925)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (478, 643, 1932)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4840)
[M::mem_pestat] mean and std.dev: (1038.50, 1017.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6294)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 267, 451)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 979)
[M::mem_pestat] mean and std.dev: (309.81, 180.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1243)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700344 sequences (100000194 bp) in 2.607 CPU sec, 2.756 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 284443, 25, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 277, 372)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 774)
[M::mem_pestat] mean and std.dev: (251.91, 124.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 975)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 253, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 754)
[M::mem_pestat] mean and std.dev: (276.83, 135.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 949)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 488, 1098)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2986)
[M::mem_pestat] mean and std.dev: (654.00, 526.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3930)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 310, 895)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2243)
[M::mem_pestat] mean and std.dev: (462.00, 314.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2917)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702348 sequences (100000273 bp) in 1.880 CPU sec, 1.880 real sec...
[M::mem_process_seqs] Processed 694368 reads in 166.474 CPU sec, 5.277 real sec
sorting block 25, #reads = 1081299 mem = 536876585 peak = 910016512
[M::mem_process_seqs] Processed 694102 reads in 108.638 CPU sec, 3.433 real sec
sorting block 26, #reads = 1081357 mem = 536879979 peak = 914112512
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 286912, 18, 59)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 284, 473)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1069)
[M::mem_pestat] mean and std.dev: (297.25, 186.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1367)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 234, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 710)
[M::mem_pestat] mean and std.dev: (260.68, 131.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 894)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (386, 710, 1739)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4445)
[M::mem_pestat] mean and std.dev: (1025.06, 1087.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5798)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 407, 555)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1289)
[M::mem_pestat] mean and std.dev: (428.83, 324.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1728)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699566 sequences (100000124 bp) in 2.463 CPU sec, 2.561 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 288064, 5, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 260, 381)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 761)
[M::mem_pestat] mean and std.dev: (278.28, 141.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 951)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 229, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 701)
[M::mem_pestat] mean and std.dev: (256.89, 130.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 883)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (139, 219, 316)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 670)
[M::mem_pestat] mean and std.dev: (229.39, 119.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 847)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 698396 sequences (100000141 bp) in 1.867 CPU sec, 1.877 real sec...
[M::mem_process_seqs] Processed 700344 reads in 168.716 CPU sec, 5.354 real sec
[M::mem_process_seqs] Processed 702348 reads in 110.280 CPU sec, 3.488 real sec
sorting block 27, #reads = 1083398 mem = 536878262 peak = 914112512
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 286565, 25, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 242, 286)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 560)
[M::mem_pestat] mean and std.dev: (210.49, 96.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 697)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 237, 349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 729)
[M::mem_pestat] mean and std.dev: (264.73, 134.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 919)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 392, 680)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1600)
[M::mem_pestat] mean and std.dev: (467.92, 301.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2060)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 422, 831)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2045)
[M::mem_pestat] mean and std.dev: (531.94, 386.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2652)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 697384 sequences (100000195 bp) in 2.205 CPU sec, 2.331 real sec...
[M::process] read 696532 sequences (100000168 bp) in 1.610 CPU sec, 1.609 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 286367, 20, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 243, 413)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 913)
[M::mem_pestat] mean and std.dev: (279.50, 178.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1163)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 243, 356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 744)
[M::mem_pestat] mean and std.dev: (269.99, 136.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 938)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (482, 1029, 1624)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3908)
[M::mem_pestat] mean and std.dev: (794.76, 546.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5050)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 281, 497)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1003)
[M::mem_pestat] mean and std.dev: (330.65, 161.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1256)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699566 reads in 173.002 CPU sec, 5.726 real sec
[M::mem_process_seqs] Processed 698396 reads in 111.296 CPU sec, 3.560 real sec
sorting block 28, #reads = 1084907 mem = 536878348 peak = 914112512
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 285306, 28, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (138, 375, 1131)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3117)
[M::mem_pestat] mean and std.dev: (506.38, 590.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4110)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 245, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 748)
[M::mem_pestat] mean and std.dev: (271.91, 137.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 943)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (435, 1030, 2349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6177)
[M::mem_pestat] mean and std.dev: (1269.24, 1095.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8091)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (265, 471, 988)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2434)
[M::mem_pestat] mean and std.dev: (590.40, 447.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3157)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695774 sequences (100000249 bp) in 2.160 CPU sec, 2.255 real sec...
[M::process] read 695432 sequences (100000224 bp) in 1.910 CPU sec, 1.910 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 284825, 25, 63)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 295, 634)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1474)
[M::mem_pestat] mean and std.dev: (369.67, 269.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1894)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 248, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 756)
[M::mem_pestat] mean and std.dev: (274.03, 137.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 953)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (120, 561, 2338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6774)
[M::mem_pestat] mean and std.dev: (1652.80, 2261.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10699)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 285, 502)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1130)
[M::mem_pestat] mean and std.dev: (336.26, 226.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1444)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 697384 reads in 171.868 CPU sec, 5.487 real sec
sorting block 29, #reads = 1082670 mem = 536880445 peak = 914112512
[M::mem_process_seqs] Processed 696532 reads in 108.242 CPU sec, 3.437 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 284904, 17, 80)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 371, 2241)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6311)
[M::mem_pestat] mean and std.dev: (1107.96, 1225.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8346)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 248, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 748)
[M::mem_pestat] mean and std.dev: (273.61, 136.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 942)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (74, 479, 3175)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9377)
[M::mem_pestat] mean and std.dev: (1657.53, 2025.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12478)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 306, 465)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 993)
[M::mem_pestat] mean and std.dev: (317.46, 176.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1257)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 30, #reads = 1079976 mem = 536878791 peak = 933310464
[M::process] read 694952 sequences (100000125 bp) in 2.165 CPU sec, 2.288 real sec...
[M::process] read 694774 sequences (100000255 bp) in 1.450 CPU sec, 1.448 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 285265, 20, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 304, 526)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1232)
[M::mem_pestat] mean and std.dev: (324.42, 220.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1585)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 249, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 749)
[M::mem_pestat] mean and std.dev: (274.61, 136.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 943)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (144, 1069, 1698)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4806)
[M::mem_pestat] mean and std.dev: (1114.65, 1125.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6360)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 281, 536)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1266)
[M::mem_pestat] mean and std.dev: (333.87, 263.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1631)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 695774 reads in 169.965 CPU sec, 5.415 real sec
[M::mem_process_seqs] Processed 695432 reads in 112.208 CPU sec, 3.574 real sec
sorting block 31, #reads = 1079278 mem = 536878531 peak = 933310464
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 284512, 18, 64)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 257, 378)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 830)
[M::mem_pestat] mean and std.dev: (275.42, 164.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1056)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 251, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 750)
[M::mem_pestat] mean and std.dev: (275.67, 136.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 944)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (935, 1698, 2456)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5498)
[M::mem_pestat] mean and std.dev: (1515.81, 954.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7019)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 247, 587)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1425)
[M::mem_pestat] mean and std.dev: (321.16, 238.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1844)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 701916 sequences (100000159 bp) in 2.649 CPU sec, 2.767 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 284954, 26, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 374, 882)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2292)
[M::mem_pestat] mean and std.dev: (556.98, 552.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2997)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 252, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 756)
[M::mem_pestat] mean and std.dev: (276.74, 137.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 952)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (441, 794, 2048)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5262)
[M::mem_pestat] mean and std.dev: (1184.15, 1070.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6869)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 253, 488)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1106)
[M::mem_pestat] mean and std.dev: (312.49, 207.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1415)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 706114 sequences (100000135 bp) in 1.900 CPU sec, 1.901 real sec...
[M::mem_process_seqs] Processed 694952 reads in 176.425 CPU sec, 5.823 real sec
[M::mem_process_seqs] Processed 694774 reads in 114.008 CPU sec, 3.615 real sec
sorting block 32, #reads = 1079100 mem = 536880489 peak = 933310464
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 287333, 13, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 371, 636)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1582)
[M::mem_pestat] mean and std.dev: (439.55, 320.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2055)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 229, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 695)
[M::mem_pestat] mean and std.dev: (255.86, 128.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 875)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (357, 494, 1014)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2328)
[M::mem_pestat] mean and std.dev: (478.45, 300.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2985)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 301, 670)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1614)
[M::mem_pestat] mean and std.dev: (373.45, 277.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2086)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702650 sequences (100000188 bp) in 2.270 CPU sec, 2.369 real sec...
[M::process] read 700912 sequences (100000089 bp) in 1.440 CPU sec, 1.440 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 288986, 18, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 260, 900)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2352)
[M::mem_pestat] mean and std.dev: (393.37, 329.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3078)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 219, 320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 660)
[M::mem_pestat] mean and std.dev: (244.96, 122.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 830)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (342, 537, 2725)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7491)
[M::mem_pestat] mean and std.dev: (870.00, 918.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9874)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 333, 660)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1596)
[M::mem_pestat] mean and std.dev: (426.77, 370.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2064)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 701916 reads in 182.475 CPU sec, 5.831 real sec
[M::mem_process_seqs] Processed 706114 reads in 121.886 CPU sec, 3.902 real sec
sorting block 33, #reads = 1078218 mem = 536880768 peak = 933310464
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 288500, 15, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 322, 512)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1172)
[M::mem_pestat] mean and std.dev: (326.28, 238.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1502)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 228, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 692)
[M::mem_pestat] mean and std.dev: (254.83, 127.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 871)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (370, 876, 1737)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4471)
[M::mem_pestat] mean and std.dev: (1137.40, 991.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5838)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 277, 621)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1521)
[M::mem_pestat] mean and std.dev: (345.61, 250.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1971)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699976 sequences (100000157 bp) in 2.460 CPU sec, 2.638 real sec...
[M::process] read 698022 sequences (100000019 bp) in 1.612 CPU sec, 1.622 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 287414, 7, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 259, 620)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1550)
[M::mem_pestat] mean and std.dev: (343.18, 331.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2015)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 233, 342)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 712)
[M::mem_pestat] mean and std.dev: (260.06, 130.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 897)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 248, 396)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 806)
[M::mem_pestat] mean and std.dev: (255.44, 103.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1011)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702650 reads in 186.634 CPU sec, 5.990 real sec
sorting block 34, #reads = 1082825 mem = 536878289 peak = 933310464
[M::mem_process_seqs] Processed 700912 reads in 123.274 CPU sec, 4.007 real sec
sorting block 35, #reads = 1081890 mem = 536879109 peak = 933310464
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 286995, 13, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 268, 446)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 970)
[M::mem_pestat] mean and std.dev: (354.57, 205.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1232)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 237, 347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 723)
[M::mem_pestat] mean and std.dev: (263.67, 132.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 911)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (123, 164, 1939)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5571)
[M::mem_pestat] mean and std.dev: (554.67, 797.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7387)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 277, 800)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2082)
[M::mem_pestat] mean and std.dev: (450.68, 484.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2723)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696802 sequences (100000194 bp) in 2.515 CPU sec, 2.690 real sec...
[M::process] read 696234 sequences (100000158 bp) in 1.832 CPU sec, 1.834 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 286020, 13, 52)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 233, 524)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1264)
[M::mem_pestat] mean and std.dev: (310.64, 277.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1634)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 243, 355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 741)
[M::mem_pestat] mean and std.dev: (269.45, 135.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 934)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1593, 2593, 4270)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9624)
[M::mem_pestat] mean and std.dev: (3180.38, 2483.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13114)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 278, 514)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1146)
[M::mem_pestat] mean and std.dev: (345.25, 216.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1462)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 699976 reads in 191.494 CPU sec, 6.194 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 285792, 13, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 395, 780)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1970)
[M::mem_pestat] mean and std.dev: (391.78, 309.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2565)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 245, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 746)
[M::mem_pestat] mean and std.dev: (271.75, 136.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 940)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (486, 943, 1324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3000)
[M::mem_pestat] mean and std.dev: (909.15, 556.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3838)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 278, 1410)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3926)
[M::mem_pestat] mean and std.dev: (656.50, 704.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5184)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695028 sequences (100000240 bp) in 1.978 CPU sec, 2.067 real sec...
[M::mem_process_seqs] Processed 696802 reads in 108.026 CPU sec, 3.458 real sec
sorting block 36, #reads = 1081713 mem = 536877742 peak = 933310464
[M::mem_process_seqs] Processed 698022 reads in 267.206 CPU sec, 8.547 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 285426, 21, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (154, 237, 748)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1936)
[M::mem_pestat] mean and std.dev: (384.87, 353.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2530)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 247, 357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 741)
[M::mem_pestat] mean and std.dev: (272.17, 135.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 933)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (336, 1342, 1880)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4968)
[M::mem_pestat] mean and std.dev: (1143.63, 1105.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6512)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 301, 506)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1134)
[M::mem_pestat] mean and std.dev: (367.33, 220.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1448)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 37, #reads = 1079247 mem = 536879725 peak = 1028415488
[M::process] read 695162 sequences (100000101 bp) in 2.633 CPU sec, 2.807 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 284610, 20, 60)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 273, 422)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 950)
[M::mem_pestat] mean and std.dev: (276.41, 169.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1214)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 250, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 750)
[M::mem_pestat] mean and std.dev: (275.40, 136.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 944)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (391, 544, 1014)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2260)
[M::mem_pestat] mean and std.dev: (587.89, 461.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2883)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 339, 453)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 947)
[M::mem_pestat] mean and std.dev: (312.17, 140.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1194)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696234 reads in 206.058 CPU sec, 6.549 real sec
[M::process] read 704994 sequences (100000149 bp) in 1.885 CPU sec, 1.896 real sec...
[M::mem_process_seqs] Processed 695028 reads in 121.898 CPU sec, 3.864 real sec
sorting block 38, #reads = 1080736 mem = 536881281 peak = 1028415488
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 284779, 16, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 375, 764)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1934)
[M::mem_pestat] mean and std.dev: (487.97, 387.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2519)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 250, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 758)
[M::mem_pestat] mean and std.dev: (275.76, 137.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 955)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (354, 576, 2160)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5772)
[M::mem_pestat] mean and std.dev: (898.00, 937.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7578)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 247, 598)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1418)
[M::mem_pestat] mean and std.dev: (370.87, 318.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1828)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702620 sequences (100000024 bp) in 2.567 CPU sec, 2.994 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 288573, 29, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 258, 506)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1142)
[M::mem_pestat] mean and std.dev: (326.02, 206.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1460)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 222, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 676)
[M::mem_pestat] mean and std.dev: (249.05, 125.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 851)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 496, 8609)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 25401)
[M::mem_pestat] mean and std.dev: (3246.83, 4068.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 33797)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 325, 559)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1325)
[M::mem_pestat] mean and std.dev: (325.45, 243.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1708)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700182 sequences (100000212 bp) in 1.902 CPU sec, 1.905 real sec...
[M::mem_process_seqs] Processed 695162 reads in 192.509 CPU sec, 6.195 real sec
[M::mem_process_seqs] Processed 704994 reads in 127.063 CPU sec, 4.065 real sec
sorting block 39, #reads = 1079088 mem = 536877885 peak = 1028415488
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 287526, 19, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 299, 1133)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3005)
[M::mem_pestat] mean and std.dev: (550.66, 496.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3941)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 230, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 698)
[M::mem_pestat] mean and std.dev: (255.55, 127.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 879)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (140, 1312, 2525)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7295)
[M::mem_pestat] mean and std.dev: (1361.84, 1260.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9680)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 395, 676)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1698)
[M::mem_pestat] mean and std.dev: (429.30, 340.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2209)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 699148 sequences (100000021 bp) in 2.747 CPU sec, 3.237 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 287162, 25, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 230, 814)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2070)
[M::mem_pestat] mean and std.dev: (348.21, 291.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2698)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 237, 345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 717)
[M::mem_pestat] mean and std.dev: (262.09, 130.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 903)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 577, 1903)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5367)
[M::mem_pestat] mean and std.dev: (984.72, 1101.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7099)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 345, 586)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1360)
[M::mem_pestat] mean and std.dev: (349.59, 246.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1747)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702620 reads in 179.337 CPU sec, 5.805 real sec
[M::process] read 698784 sequences (100000078 bp) in 1.937 CPU sec, 2.038 real sec...
sorting block 40, #reads = 1083408 mem = 536881199 peak = 1028415488
[M::mem_process_seqs] Processed 700182 reads in 123.637 CPU sec, 4.014 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 287363, 8, 56)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 309, 680)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1660)
[M::mem_pestat] mean and std.dev: (406.44, 365.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2150)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 240, 350)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 730)
[M::mem_pestat] mean and std.dev: (265.44, 132.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 920)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 287, 464)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1074)
[M::mem_pestat] mean and std.dev: (290.67, 168.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1379)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 41, #reads = 1085878 mem = 536880968 peak = 1028415488
[M::process] read 698310 sequences (100000041 bp) in 2.422 CPU sec, 2.823 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 286562, 15, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (143, 239, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 719)
[M::mem_pestat] mean and std.dev: (220.91, 96.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 911)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 242, 351)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 731)
[M::mem_pestat] mean and std.dev: (266.37, 132.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 921)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (242, 675, 1620)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4376)
[M::mem_pestat] mean and std.dev: (975.57, 971.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5754)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 283, 425)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 883)
[M::mem_pestat] mean and std.dev: (289.65, 131.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1112)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696974 sequences (100000251 bp) in 1.714 CPU sec, 1.716 real sec...
[M::mem_process_seqs] Processed 699148 reads in 184.146 CPU sec, 6.015 real sec
[M::mem_process_seqs] Processed 698784 reads in 120.411 CPU sec, 3.918 real sec
sorting block 42, #reads = 1084271 mem = 536878559 peak = 1028415488
[M::process] read 696616 sequences (100000157 bp) in 2.600 CPU sec, 2.835 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 285607, 19, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 336, 1057)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2807)
[M::mem_pestat] mean and std.dev: (591.47, 485.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3682)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 246, 357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 743)
[M::mem_pestat] mean and std.dev: (271.29, 135.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 936)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (299, 637, 1639)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4319)
[M::mem_pestat] mean and std.dev: (952.06, 1077.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5659)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 267, 983)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2601)
[M::mem_pestat] mean and std.dev: (531.21, 544.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3410)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695710 sequences (100000103 bp) in 1.926 CPU sec, 1.933 real sec...
[M::mem_process_seqs] Processed 696974 reads in 111.211 CPU sec, 3.526 real sec
sorting block 43, #reads = 1081744 mem = 536876898 peak = 1028415488
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 286312, 22, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 304, 457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 971)
[M::mem_pestat] mean and std.dev: (306.32, 158.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1228)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 241, 350)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 728)
[M::mem_pestat] mean and std.dev: (266.25, 132.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 917)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 1119, 2535)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7199)
[M::mem_pestat] mean and std.dev: (1316.71, 1241.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9531)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 321, 751)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1837)
[M::mem_pestat] mean and std.dev: (408.54, 318.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2380)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 286072, 35, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 224, 449)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1023)
[M::mem_pestat] mean and std.dev: (276.89, 181.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1310)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 246, 356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 738)
[M::mem_pestat] mean and std.dev: (270.78, 134.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 929)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (673, 1382, 1764)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3946)
[M::mem_pestat] mean and std.dev: (1082.16, 644.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5037)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 313, 713)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1717)
[M::mem_pestat] mean and std.dev: (453.45, 375.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2219)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 695496 sequences (100000082 bp) in 2.089 CPU sec, 2.101 real sec...
[M::mem_process_seqs] Processed 698310 reads in 295.341 CPU sec, 9.471 real sec
[M::mem_process_seqs] Processed 696616 reads in 149.186 CPU sec, 4.773 real sec
sorting block 44, #reads = 1082031 mem = 536878908 peak = 1028415488
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 284991, 17, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 384, 1177)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3169)
[M::mem_pestat] mean and std.dev: (638.24, 602.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4165)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 248, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 745)
[M::mem_pestat] mean and std.dev: (273.35, 135.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 938)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (284, 848, 1787)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4793)
[M::mem_pestat] mean and std.dev: (984.47, 748.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6296)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 324, 567)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1271)
[M::mem_pestat] mean and std.dev: (303.84, 158.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1623)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 708084 sequences (100000147 bp) in 2.671 CPU sec, 2.819 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 285408, 20, 67)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 264, 868)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2284)
[M::mem_pestat] mean and std.dev: (530.32, 546.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2992)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 249, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 746)
[M::mem_pestat] mean and std.dev: (274.03, 136.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 939)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (295, 1004, 1485)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3865)
[M::mem_pestat] mean and std.dev: (890.11, 744.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5055)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 340, 612)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1474)
[M::mem_pestat] mean and std.dev: (358.72, 278.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1905)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 705836 sequences (100000102 bp) in 1.977 CPU sec, 1.983 real sec...
[M::mem_process_seqs] Processed 695710 reads in 197.070 CPU sec, 6.287 real sec
[M::mem_process_seqs] Processed 695496 reads in 142.199 CPU sec, 4.539 real sec
sorting block 45, #reads = 1077924 mem = 536880981 peak = 1028415488
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 289695, 13, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 271, 533)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1283)
[M::mem_pestat] mean and std.dev: (315.98, 244.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1658)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 214, 312)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 642)
[M::mem_pestat] mean and std.dev: (239.94, 119.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 807)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (235, 465, 2796)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7918)
[M::mem_pestat] mean and std.dev: (1590.00, 2046.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10479)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 272, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 644)
[M::mem_pestat] mean and std.dev: (251.93, 100.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 797)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 702480 sequences (100000074 bp) in 2.587 CPU sec, 2.842 real sec...
[M::process] read 701392 sequences (100000282 bp) in 1.979 CPU sec, 1.983 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 289261, 23, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 455, 1572)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4400)
[M::mem_pestat] mean and std.dev: (851.74, 915.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5814)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 221, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 672)
[M::mem_pestat] mean and std.dev: (247.38, 123.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 846)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (597, 1913, 5820)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 16266)
[M::mem_pestat] mean and std.dev: (2613.65, 2527.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 21489)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 288, 495)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1055)
[M::mem_pestat] mean and std.dev: (285.57, 139.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1335)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 708084 reads in 203.874 CPU sec, 6.548 real sec
[M::mem_process_seqs] Processed 705836 reads in 133.337 CPU sec, 4.293 real sec
sorting block 46, #reads = 1075320 mem = 536880778 peak = 1028415488
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 287947, 15, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 249, 423)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 899)
[M::mem_pestat] mean and std.dev: (261.28, 145.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1137)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 230, 336)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 698)
[M::mem_pestat] mean and std.dev: (255.80, 127.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 879)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (620, 631, 1773)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4079)
[M::mem_pestat] mean and std.dev: (1085.13, 901.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5232)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 302, 596)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1392)
[M::mem_pestat] mean and std.dev: (419.42, 352.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1829)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 700924 sequences (100000058 bp) in 2.595 CPU sec, 2.765 real sec...
[M::process] read 698000 sequences (100000195 bp) in 1.828 CPU sec, 1.836 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 287402, 23, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 283, 808)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2094)
[M::mem_pestat] mean and std.dev: (445.34, 363.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2737)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 234, 344)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 718)
[M::mem_pestat] mean and std.dev: (260.64, 131.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 905)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 785, 1645)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4543)
[M::mem_pestat] mean and std.dev: (890.78, 843.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5992)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 321, 672)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1656)
[M::mem_pestat] mean and std.dev: (502.82, 446.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2290)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 702480 reads in 199.054 CPU sec, 6.580 real sec
sorting block 47, #reads = 1083812 mem = 536881244 peak = 1028415488
[M::mem_process_seqs] Processed 701392 reads in 125.031 CPU sec, 3.963 real sec
sorting block 48, #reads = 1080688 mem = 536883252 peak = 1028415488
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 287523, 30, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 314, 537)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1221)
[M::mem_pestat] mean and std.dev: (340.16, 230.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1563)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 234, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 715)
[M::mem_pestat] mean and std.dev: (260.51, 131.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 901)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 569, 945)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2459)
[M::mem_pestat] mean and std.dev: (549.54, 384.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3216)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (267, 401, 588)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1230)
[M::mem_pestat] mean and std.dev: (409.31, 232.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1551)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 696236 sequences (100000023 bp) in 2.583 CPU sec, 2.746 real sec...
[M::process] read 695342 sequences (100000122 bp) in 1.972 CPU sec, 1.977 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 286237, 9, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 310, 1493)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4065)
[M::mem_pestat] mean and std.dev: (863.15, 1073.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5351)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 241, 351)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 729)
[M::mem_pestat] mean and std.dev: (266.41, 131.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 918)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (240, 307, 1000)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2520)
[M::mem_pestat] mean and std.dev: (516.48, 454.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3280)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 700924 reads in 193.844 CPU sec, 6.203 real sec
[M::mem_process_seqs] Processed 698000 reads in 136.763 CPU sec, 4.479 real sec
sorting block 49, #reads = 1080811 mem = 536880449 peak = 1028415488
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (77, 285746, 23, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 355, 963)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2467)
[M::mem_pestat] mean and std.dev: (440.02, 403.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3219)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 247, 355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 735)
[M::mem_pestat] mean and std.dev: (270.40, 132.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 925)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (539, 1112, 1961)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4805)
[M::mem_pestat] mean and std.dev: (1232.24, 996.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6227)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 299, 1425)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3841)
[M::mem_pestat] mean and std.dev: (723.14, 719.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5049)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 694334 sequences (100000123 bp) in 2.494 CPU sec, 2.738 real sec...
[M::process] read 497568 sequences (71656473 bp) in 1.500 CPU sec, 1.503 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 285183, 20, 61)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 214, 496)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1174)
[M::mem_pestat] mean and std.dev: (256.35, 166.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1513)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 248, 353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 725)
[M::mem_pestat] mean and std.dev: (270.01, 130.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 911)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (382, 572, 1438)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3550)
[M::mem_pestat] mean and std.dev: (812.95, 742.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4606)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (230, 312, 584)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1292)
[M::mem_pestat] mean and std.dev: (333.73, 203.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1646)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 696236 reads in 190.440 CPU sec, 6.124 real sec
[M::mem_process_seqs] Processed 695342 reads in 125.435 CPU sec, 4.009 real sec
sorting block 50, #reads = 1080116 mem = 536880445 peak = 1028415488
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 284611, 14, 58)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 273, 751)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1949)
[M::mem_pestat] mean and std.dev: (404.64, 343.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2548)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 252, 362)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 748)
[M::mem_pestat] mean and std.dev: (275.59, 135.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 941)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (371, 461, 1926)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5036)
[M::mem_pestat] mean and std.dev: (489.45, 481.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6591)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 343, 454)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 980)
[M::mem_pestat] mean and std.dev: (303.92, 147.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1243)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 204168, 28, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 295, 854)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2264)
[M::mem_pestat] mean and std.dev: (473.06, 481.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2969)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 254, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 760)
[M::mem_pestat] mean and std.dev: (278.21, 137.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 957)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (306, 514, 2661)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7371)
[M::mem_pestat] mean and std.dev: (1431.11, 1718.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9726)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 324, 580)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1308)
[M::mem_pestat] mean and std.dev: (368.27, 246.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1672)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 694334 reads in 162.081 CPU sec, 5.327 real sec
sorting block 51, #reads = 1079403 mem = 536877650 peak = 1039630336
[M::mem_process_seqs] Processed 497568 reads in 94.682 CPU sec, 3.070 real sec
sorting block 52, #reads = 1079392 mem = 536878934 peak = 1039630336
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000a06d1
  features: 1f8bfbff fffab20b
  extended: f1bf27eb 1b407f7e
  amd bits: 2c100800 00000121
     brand: Intel(R) Xeon(R) 6975P-C
threads: 31
algo: bwa-mem
license: sentieon:klib=31
reads: 57000538
overall: 69982228480 mem 9345.756 user 369.047 sys 331.652 real
[main] Version: 0.7.17-r1188
[main] CMD: /opt/conda/share/sentieon-202308.03-3/libexec/bwa mem -K 100000000 -Y -R @RG\tID:A23MHWWLT4.1136_5TB-T1-TDNA-1_A23MHWWLT4_1.L004\tPU:L004\tSM:1136_5TB-T1-TDNA-1_A23MHWWLT4_1\tLB:1136_5TB-T1-TDNA-1_A23MHWWLT4_1\tDS:s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta\tPL:ILLUMINA -t 31 ./BWAIndex/Homo_sapiens_assembly38.fasta.64 0004.1136_5TB-T1-TDNA-1_A23MHWWLT4_1_R1.fastq.gz 0004.1136_5TB-T1-TDNA-1_A23MHWWLT4_1_R2.fastq.gz
[main] Real time: 331.689 sec; CPU: 9714.807 sec
sorting block 53, #reads = 20328 mem = 10179159 peak = 1039630336
uniq header count 1
merging 54 blocks
sw version: sentieon-genomics-202308.03
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000a06d1
  features: 1f8bfbff fffab20b
  extended: f1bf27eb 1b407f7e
  amd bits: 2c100800 00000121
     brand: Intel(R) Xeon(R) 6975P-C
threads: 31 max 192
algo: util-sort
license: sentieon:util=1
output file size: 3326421452
output reads: 57373101
bam_mem_sort: 54 calls 31.226 user 0.927 sys 32.364 real
bam_write: 54 calls 16.806 user 0.937 sys 24.174 real
execute: 1 calls 18.091 user 2.333 sys 359.586 real
merge_files: 1 calls 18.085 user 2.297 sys 27.878 real
parse_chunk: 849 calls 35.491 user 9.564 sys 48.321 real
read_chunk: 2295 calls 20.090 user 16.453 sys 269.887 real
sort_block: 1 calls 12.006 user 15.555 sys 255.249 real
write_chunk: 1444 calls 17.382 user 2.013 sys 26.518 real
overall: 2693287936 mem 840.922 user 41.120 sys 359.608 real
ls: cannot access '*.cram': No such file or directory