.command.log - Workdir - DAQ:SENTIEON_BWAMEM (1136_5Q-T1-TDNA-1_A23MHWWLT4_1;L002;0001)

File Info

Filename: .command.log
Full Path: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/02/22e3354c027104394b06b8c2dbd31d/.command.log
Size: 322.8 KB
Task: DAQ:SENTIEON_BWAMEM (1136_5Q-T1-TDNA-1_A23MHWWLT4_1;L002;0001)
Attempt
Content

  Downloading: s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/0c/148ad0d67f567d0ce1202c8956b7dc/1136_5Q-T1-TDNA-1_A23MHWWLT4_1/1136_5Q-T1-TDNA-1_A23MHWWLT4_1_R2.fastq.gz
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/02/22e3354c027104394b06b8c2dbd31d/.command.sh
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/0c/148ad0d67f567d0ce1202c8956b7dc/1136_5Q-T1-TDNA-1_A23MHWWLT4_1/1136_5Q-T1-TDNA-1_A23MHWWLT4_1_R1.fastq.gz
  Downloading: s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta.fai
  Downloading: s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/BWAIndex
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/02/22e3354c027104394b06b8c2dbd31d/.command.run
==> STAGING COMPLETE (7 inputs)

This software is licensed to bgold@natera.com by Sentieon Inc.
cmdline: /opt/conda/share/sentieon-202308.03-3/libexec/util sort -r Homo_sapiens_assembly38.fasta -t 31 -o 1136_5Q-T1-TDNA-1_A23MHWWLT4_1.bam --sam2bam -
This software is licensed to bgold@natera.com by Sentieon Inc.
version: sentieon-genomics-202308.03
[M::bwa_idx_load_from_disk] read 3171 ALT contigs
[M::main_mem] bwa index loaded in 1383.141 CPU sec, 47.802 real sec
[M::process] read 685184 sequences (100000023 bp) in 1.183 CPU sec, 1.193 real sec...
[M::process] read 684010 sequences (100000030 bp) in 1.630 CPU sec, 1.621 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 283316, 2, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 208, 419)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 935)
[M::mem_pestat] mean and std.dev: (230.44, 111.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1193)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 297, 415)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 853)
[M::mem_pestat] mean and std.dev: (315.68, 150.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1072)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (155, 246, 419)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 947)
[M::mem_pestat] mean and std.dev: (265.73, 126.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1211)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 683440 sequences (100000196 bp) in 1.620 CPU sec, 1.620 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (21, 282798, 5, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (189, 249, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 618)
[M::mem_pestat] mean and std.dev: (278.71, 107.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 761)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 302, 422)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 868)
[M::mem_pestat] mean and std.dev: (320.89, 152.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1091)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 251, 354)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 698)
[M::mem_pestat] mean and std.dev: (280.04, 121.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 870)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 683258 sequences (100000052 bp) in 1.649 CPU sec, 1.650 real sec...
[M::mem_process_seqs] Processed 685184 reads in 169.023 CPU sec, 5.305 real sec
[M::mem_process_seqs] Processed 684010 reads in 117.467 CPU sec, 3.737 real sec
sorting block 0, #reads = 1080383 mem = 536877444 peak = 594714624
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 282836, 10, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 241, 751)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1917)
[M::mem_pestat] mean and std.dev: (389.95, 385.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2500)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 306, 425)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 871)
[M::mem_pestat] mean and std.dev: (324.01, 153.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1094)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (578, 1540, 3693)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9923)
[M::mem_pestat] mean and std.dev: (1719.60, 1386.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13038)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 204, 1852)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5236)
[M::mem_pestat] mean and std.dev: (754.60, 956.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6928)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682874 sequences (100000017 bp) in 2.137 CPU sec, 2.455 real sec...
[M::process] read 682538 sequences (100000114 bp) in 1.790 CPU sec, 1.824 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (19, 282466, 5, 17)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (128, 158, 239)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 461)
[M::mem_pestat] mean and std.dev: (173.00, 68.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 572)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 309, 429)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 879)
[M::mem_pestat] mean and std.dev: (326.89, 154.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1104)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 274, 368)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 786)
[M::mem_pestat] mean and std.dev: (247.94, 105.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 995)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683440 reads in 172.896 CPU sec, 5.688 real sec
[M::mem_process_seqs] Processed 683258 reads in 119.067 CPU sec, 3.900 real sec
sorting block 1, #reads = 1079401 mem = 536878680 peak = 717508608
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 282632, 4, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (120, 209, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 771)
[M::mem_pestat] mean and std.dev: (212.26, 113.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 988)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 312, 433)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 887)
[M::mem_pestat] mean and std.dev: (329.74, 156.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1114)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (231, 367, 549)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1185)
[M::mem_pestat] mean and std.dev: (427.76, 264.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1503)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682506 sequences (100000114 bp) in 2.060 CPU sec, 2.196 real sec...
[M::process] read 681930 sequences (100000037 bp) in 1.836 CPU sec, 1.843 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 282220, 0, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 265, 311)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 635)
[M::mem_pestat] mean and std.dev: (221.33, 86.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 797)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 314, 436)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 894)
[M::mem_pestat] mean and std.dev: (331.56, 156.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1123)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 320, 402)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 816)
[M::mem_pestat] mean and std.dev: (307.50, 146.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1023)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682874 reads in 170.628 CPU sec, 5.551 real sec
[M::mem_process_seqs] Processed 682538 reads in 117.743 CPU sec, 3.838 real sec
sorting block 2, #reads = 1079984 mem = 536878551 peak = 866017280
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 282118, 6, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (144, 203, 436)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1020)
[M::mem_pestat] mean and std.dev: (236.41, 114.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1312)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 315, 437)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 895)
[M::mem_pestat] mean and std.dev: (332.59, 157.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1124)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (234, 355, 618)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1386)
[M::mem_pestat] mean and std.dev: (427.86, 310.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1770)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681510 sequences (100000094 bp) in 2.386 CPU sec, 2.629 real sec...
[M::process] read 681624 sequences (100000003 bp) in 1.856 CPU sec, 1.859 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 281863, 6, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 260, 389)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 799)
[M::mem_pestat] mean and std.dev: (239.77, 94.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1004)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 317, 440)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 902)
[M::mem_pestat] mean and std.dev: (334.42, 158.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1133)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 268, 733)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1863)
[M::mem_pestat] mean and std.dev: (472.26, 382.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2428)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682506 reads in 172.957 CPU sec, 5.610 real sec
sorting block 3, #reads = 1079198 mem = 536880036 peak = 916738048
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 281831, 5, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 213, 294)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 576)
[M::mem_pestat] mean and std.dev: (216.59, 105.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 717)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 319, 441)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 901)
[M::mem_pestat] mean and std.dev: (336.00, 157.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1131)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 214, 444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1006)
[M::mem_pestat] mean and std.dev: (305.39, 218.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1287)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681402 sequences (100000209 bp) in 1.927 CPU sec, 1.966 real sec...
[M::mem_process_seqs] Processed 681510 reads in 99.388 CPU sec, 3.187 real sec
sorting block 4, #reads = 1079422 mem = 536877381 peak = 916738048
[M::mem_process_seqs] Processed 681930 reads in 250.847 CPU sec, 8.097 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 282354, 8, 22)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 259, 345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 735)
[M::mem_pestat] mean and std.dev: (260.21, 143.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 930)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 319, 442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 906)
[M::mem_pestat] mean and std.dev: (336.21, 158.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1138)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 253, 385)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 805)
[M::mem_pestat] mean and std.dev: (289.71, 188.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1043)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681462 sequences (100000239 bp) in 2.382 CPU sec, 2.576 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 281842, 9, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (227, 280, 353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 605)
[M::mem_pestat] mean and std.dev: (269.33, 93.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 731)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 319, 442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 904)
[M::mem_pestat] mean and std.dev: (336.64, 158.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1135)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 233, 883)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2351)
[M::mem_pestat] mean and std.dev: (358.73, 332.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3085)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681252 sequences (100000211 bp) in 1.859 CPU sec, 1.863 real sec...
[M::mem_process_seqs] Processed 681624 reads in 198.566 CPU sec, 6.375 real sec
sorting block 5, #reads = 1079342 mem = 536883357 peak = 961622016
[M::mem_process_seqs] Processed 681402 reads in 120.929 CPU sec, 3.842 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (12, 281268, 11, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 178, 279)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 525)
[M::mem_pestat] mean and std.dev: (209.00, 94.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 648)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 319, 443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 909)
[M::mem_pestat] mean and std.dev: (336.52, 158.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1142)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (35, 35, 239)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 647)
[M::mem_pestat] mean and std.dev: (146.64, 134.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 851)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 251, 307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 543)
[M::mem_pestat] mean and std.dev: (244.12, 78.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 661)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 681672 sequences (100000208 bp) in 1.977 CPU sec, 2.159 real sec...
[M::process] read 681550 sequences (100000203 bp) in 1.931 CPU sec, 1.961 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 281563, 5, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 243, 317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 629)
[M::mem_pestat] mean and std.dev: (235.16, 94.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 785)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 319, 442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 904)
[M::mem_pestat] mean and std.dev: (336.67, 158.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1135)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 228, 481)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1077)
[M::mem_pestat] mean and std.dev: (265.21, 123.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1375)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681462 reads in 170.976 CPU sec, 5.478 real sec
sorting block 6, #reads = 1079550 mem = 536878445 peak = 978321408
[M::mem_process_seqs] Processed 681252 reads in 117.718 CPU sec, 3.757 real sec
sorting block 7, #reads = 1078927 mem = 536883648 peak = 1024630784
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 280945, 6, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (140, 199, 463)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1109)
[M::mem_pestat] mean and std.dev: (268.44, 145.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1432)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 315, 439)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 901)
[M::mem_pestat] mean and std.dev: (333.91, 158.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1132)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 251, 319)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 543)
[M::mem_pestat] mean and std.dev: (248.46, 79.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 655)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681828 sequences (100000148 bp) in 2.405 CPU sec, 2.762 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 281513, 4, 19)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (117, 286, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 744)
[M::mem_pestat] mean and std.dev: (225.78, 124.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 953)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 314, 436)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 892)
[M::mem_pestat] mean and std.dev: (332.44, 156.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1120)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 206, 376)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 746)
[M::mem_pestat] mean and std.dev: (255.63, 104.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 931)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681384 sequences (100000170 bp) in 1.847 CPU sec, 2.037 real sec...
[M::mem_process_seqs] Processed 681672 reads in 173.181 CPU sec, 5.635 real sec
[M::mem_process_seqs] Processed 681550 reads in 119.282 CPU sec, 3.878 real sec
sorting block 8, #reads = 1077720 mem = 536877797 peak = 1024630784
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23, 281835, 7, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 193, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 668)
[M::mem_pestat] mean and std.dev: (228.14, 147.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 835)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 314, 436)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 892)
[M::mem_pestat] mean and std.dev: (332.29, 157.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1120)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 243, 372)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 736)
[M::mem_pestat] mean and std.dev: (235.34, 84.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 918)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681476 sequences (100000004 bp) in 2.514 CPU sec, 2.976 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 281752, 4, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 266, 485)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1045)
[M::mem_pestat] mean and std.dev: (292.62, 132.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1325)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 316, 438)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 896)
[M::mem_pestat] mean and std.dev: (333.42, 156.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1125)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 282, 353)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 661)
[M::mem_pestat] mean and std.dev: (282.70, 98.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 815)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681310 sequences (100000111 bp) in 1.809 CPU sec, 1.839 real sec...
[M::mem_process_seqs] Processed 681828 reads in 175.505 CPU sec, 5.747 real sec
[M::mem_process_seqs] Processed 681384 reads in 121.145 CPU sec, 3.952 real sec
sorting block 9, #reads = 1079193 mem = 536881066 peak = 1024630784
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 281911, 2, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (227, 355, 575)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1271)
[M::mem_pestat] mean and std.dev: (367.97, 197.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1619)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 317, 439)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 897)
[M::mem_pestat] mean and std.dev: (334.57, 157.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1126)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (246, 268, 457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 879)
[M::mem_pestat] mean and std.dev: (324.35, 166.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1090)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681202 sequences (100000114 bp) in 2.460 CPU sec, 2.932 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 281522, 4, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 317, 758)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1942)
[M::mem_pestat] mean and std.dev: (400.62, 301.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2534)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 317, 438)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 892)
[M::mem_pestat] mean and std.dev: (334.83, 156.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1119)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 312, 428)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 828)
[M::mem_pestat] mean and std.dev: (314.83, 133.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1028)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681032 sequences (100000227 bp) in 1.854 CPU sec, 1.939 real sec...
[M::mem_process_seqs] Processed 681476 reads in 170.806 CPU sec, 5.605 real sec
sorting block 10, #reads = 1078214 mem = 536880439 peak = 1024630784
[M::mem_process_seqs] Processed 681310 reads in 118.243 CPU sec, 3.855 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 281832, 5, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 285, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 720)
[M::mem_pestat] mean and std.dev: (277.11, 131.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 910)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 316, 437)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 891)
[M::mem_pestat] mean and std.dev: (333.67, 156.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1118)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 336, 799)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2059)
[M::mem_pestat] mean and std.dev: (374.30, 290.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2689)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 11, #reads = 1079282 mem = 536878184 peak = 1024630784
[M::process] read 680132 sequences (100000079 bp) in 2.646 CPU sec, 3.030 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 281422, 4, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 222, 317)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 587)
[M::mem_pestat] mean and std.dev: (223.19, 82.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 722)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 318, 439)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 893)
[M::mem_pestat] mean and std.dev: (335.34, 156.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1120)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 232, 438)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 966)
[M::mem_pestat] mean and std.dev: (248.65, 127.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1230)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680568 sequences (100000217 bp) in 1.840 CPU sec, 1.850 real sec...
[M::mem_process_seqs] Processed 681202 reads in 172.161 CPU sec, 5.775 real sec
[M::mem_process_seqs] Processed 681032 reads in 119.015 CPU sec, 3.966 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 281132, 1, 15)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 254, 442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1008)
[M::mem_pestat] mean and std.dev: (296.15, 151.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1291)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 324, 444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 900)
[M::mem_pestat] mean and std.dev: (339.55, 157.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1128)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 251, 374)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 802)
[M::mem_pestat] mean and std.dev: (219.54, 84.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1016)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 12, #reads = 1079147 mem = 536879360 peak = 1024630784
[M::process] read 680556 sequences (100000288 bp) in 2.718 CPU sec, 3.195 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (21, 281100, 6, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (227, 255, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 566)
[M::mem_pestat] mean and std.dev: (259.40, 102.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 679)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 320, 438)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 888)
[M::mem_pestat] mean and std.dev: (335.43, 155.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1113)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 288, 462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 944)
[M::mem_pestat] mean and std.dev: (311.41, 159.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1185)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680132 reads in 172.543 CPU sec, 5.770 real sec
[M::process] read 680420 sequences (100000094 bp) in 1.896 CPU sec, 1.973 real sec...
[M::mem_process_seqs] Processed 680568 reads in 119.552 CPU sec, 3.990 real sec
sorting block 13, #reads = 1078263 mem = 536886486 peak = 1024630784
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 281525, 0, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 210, 350)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 700)
[M::mem_pestat] mean and std.dev: (247.54, 110.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 875)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 320, 438)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 888)
[M::mem_pestat] mean and std.dev: (335.71, 155.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1113)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (141, 220, 357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 789)
[M::mem_pestat] mean and std.dev: (274.55, 165.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1005)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680304 sequences (100000186 bp) in 2.618 CPU sec, 3.153 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 281412, 8, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (263, 310, 429)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 761)
[M::mem_pestat] mean and std.dev: (313.05, 115.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 927)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 318, 435)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 879)
[M::mem_pestat] mean and std.dev: (334.14, 153.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1101)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 279, 446)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 940)
[M::mem_pestat] mean and std.dev: (297.79, 164.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1187)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680556 reads in 168.676 CPU sec, 5.559 real sec
[M::process] read 680012 sequences (100000162 bp) in 1.866 CPU sec, 1.948 real sec...
[M::mem_process_seqs] Processed 680420 reads in 116.483 CPU sec, 3.801 real sec
sorting block 14, #reads = 1078836 mem = 536879428 peak = 1024630784
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (19, 281443, 5, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (126, 156, 284)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 600)
[M::mem_pestat] mean and std.dev: (184.22, 84.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 758)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 321, 439)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 887)
[M::mem_pestat] mean and std.dev: (337.30, 155.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1111)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 238, 345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 741)
[M::mem_pestat] mean and std.dev: (237.79, 117.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 939)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 679478 sequences (100000186 bp) in 2.591 CPU sec, 3.239 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 281338, 3, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 194, 264)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (6, 436)
[M::mem_pestat] mean and std.dev: (217.70, 69.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 522)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 322, 441)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 893)
[M::mem_pestat] mean and std.dev: (338.41, 156.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1119)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 291, 388)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 716)
[M::mem_pestat] mean and std.dev: (305.91, 109.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 880)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680304 reads in 168.740 CPU sec, 5.583 real sec
sorting block 15, #reads = 1079359 mem = 536878555 peak = 1024630784
[M::mem_process_seqs] Processed 680012 reads in 116.748 CPU sec, 3.856 real sec
[M::process] read 679476 sequences (100000191 bp) in 2.331 CPU sec, 2.504 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 281133, 1, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 254, 1059)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2829)
[M::mem_pestat] mean and std.dev: (463.08, 465.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3714)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 327, 447)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 907)
[M::mem_pestat] mean and std.dev: (342.80, 158.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1137)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (239, 263, 348)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (21, 566)
[M::mem_pestat] mean and std.dev: (280.55, 88.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 675)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 16, #reads = 1078380 mem = 536878093 peak = 1058619392
[M::process] read 681584 sequences (100000032 bp) in 2.566 CPU sec, 2.778 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 280874, 4, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 275, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 667)
[M::mem_pestat] mean and std.dev: (237.71, 95.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 840)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 328, 448)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 904)
[M::mem_pestat] mean and std.dev: (343.82, 158.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1132)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 252, 329)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (23, 533)
[M::mem_pestat] mean and std.dev: (248.00, 67.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 635)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 679478 reads in 166.047 CPU sec, 5.373 real sec
[M::process] read 684310 sequences (100000098 bp) in 1.901 CPU sec, 1.927 real sec...
[M::mem_process_seqs] Processed 679476 reads in 115.964 CPU sec, 3.699 real sec
sorting block 17, #reads = 1078650 mem = 536876954 peak = 1058619392
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 281810, 10, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 259, 1212)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3272)
[M::mem_pestat] mean and std.dev: (458.52, 489.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4302)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 316, 436)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 888)
[M::mem_pestat] mean and std.dev: (333.05, 155.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1114)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (258, 1088, 1088)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2748)
[M::mem_pestat] mean and std.dev: (748.80, 637.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3578)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 240, 443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 947)
[M::mem_pestat] mean and std.dev: (292.04, 159.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1199)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 683808 sequences (100000059 bp) in 2.699 CPU sec, 2.884 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (22, 282883, 3, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (240, 355, 760)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1800)
[M::mem_pestat] mean and std.dev: (408.81, 317.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2320)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 302, 421)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 865)
[M::mem_pestat] mean and std.dev: (320.83, 153.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1087)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 280, 680)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1654)
[M::mem_pestat] mean and std.dev: (414.43, 292.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2141)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 683326 sequences (100000168 bp) in 1.941 CPU sec, 1.942 real sec...
[M::mem_process_seqs] Processed 681584 reads in 169.360 CPU sec, 5.417 real sec
[M::mem_process_seqs] Processed 684310 reads in 118.207 CPU sec, 3.797 real sec
sorting block 18, #reads = 1077128 mem = 536881628 peak = 1058619392
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (21, 282913, 5, 22)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (128, 140, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 710)
[M::mem_pestat] mean and std.dev: (198.52, 92.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 904)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 309, 431)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 889)
[M::mem_pestat] mean and std.dev: (327.33, 156.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1118)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 239, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 731)
[M::mem_pestat] mean and std.dev: (228.81, 93.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 925)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682690 sequences (100000180 bp) in 2.726 CPU sec, 3.054 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 282394, 4, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 233, 413)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 903)
[M::mem_pestat] mean and std.dev: (290.88, 158.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1148)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 312, 434)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 894)
[M::mem_pestat] mean and std.dev: (329.51, 157.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1124)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 308, 399)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 893)
[M::mem_pestat] mean and std.dev: (280.09, 137.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1140)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683808 reads in 170.334 CPU sec, 5.502 real sec
[M::process] read 682888 sequences (100000257 bp) in 1.978 CPU sec, 1.998 real sec...
sorting block 19, #reads = 1081864 mem = 536877103 peak = 1058619392
[M::mem_process_seqs] Processed 683326 reads in 118.959 CPU sec, 3.830 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (19, 282299, 11, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 178, 346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 740)
[M::mem_pestat] mean and std.dev: (205.94, 85.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 937)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 312, 435)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 895)
[M::mem_pestat] mean and std.dev: (330.33, 157.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1125)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (343, 719, 3347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9355)
[M::mem_pestat] mean and std.dev: (2069.27, 2675.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12769)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (142, 265, 461)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1099)
[M::mem_pestat] mean and std.dev: (302.73, 175.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1418)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682124 sequences (100000166 bp) in 2.711 CPU sec, 2.937 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20, 282959, 7, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (136, 288, 676)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1756)
[M::mem_pestat] mean and std.dev: (349.84, 294.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2296)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 314, 436)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 896)
[M::mem_pestat] mean and std.dev: (331.73, 157.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1126)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (247, 329, 646)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1444)
[M::mem_pestat] mean and std.dev: (420.48, 349.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1843)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682690 reads in 170.666 CPU sec, 5.595 real sec
[M::process] read 682120 sequences (100000219 bp) in 1.929 CPU sec, 2.016 real sec...
sorting block 20, #reads = 1081399 mem = 536878883 peak = 1058619392
[M::mem_process_seqs] Processed 682888 reads in 118.694 CPU sec, 3.888 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 281624, 11, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 267, 553)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1291)
[M::mem_pestat] mean and std.dev: (373.52, 330.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1696)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 317, 441)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 905)
[M::mem_pestat] mean and std.dev: (335.33, 159.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1137)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (402, 402, 1118)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2550)
[M::mem_pestat] mean and std.dev: (622.90, 421.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3266)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 279, 430)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 946)
[M::mem_pestat] mean and std.dev: (294.29, 199.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1204)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 21, #reads = 1081246 mem = 536878776 peak = 1082163200
[M::process] read 681576 sequences (100000204 bp) in 2.624 CPU sec, 2.953 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23, 281401, 6, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 192, 409)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 885)
[M::mem_pestat] mean and std.dev: (248.14, 162.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1123)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 319, 442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 908)
[M::mem_pestat] mean and std.dev: (335.79, 158.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1141)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 251, 401)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 775)
[M::mem_pestat] mean and std.dev: (284.52, 126.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 962)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682124 reads in 169.167 CPU sec, 5.574 real sec
[M::process] read 681484 sequences (100000261 bp) in 1.936 CPU sec, 1.981 real sec...
[M::mem_process_seqs] Processed 682120 reads in 117.977 CPU sec, 3.881 real sec
sorting block 22, #reads = 1080808 mem = 536879747 peak = 1082163200
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 281530, 6, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 238, 307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 593)
[M::mem_pestat] mean and std.dev: (222.65, 91.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 736)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 320, 444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 912)
[M::mem_pestat] mean and std.dev: (337.45, 159.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1146)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 211, 410)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 882)
[M::mem_pestat] mean and std.dev: (290.54, 172.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1118)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681210 sequences (100000081 bp) in 2.758 CPU sec, 3.090 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 281921, 3, 20)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 221, 488)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1122)
[M::mem_pestat] mean and std.dev: (307.71, 252.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1439)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 320, 443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 907)
[M::mem_pestat] mean and std.dev: (337.34, 159.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1139)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 246, 510)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1108)
[M::mem_pestat] mean and std.dev: (324.32, 207.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1407)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681576 reads in 169.801 CPU sec, 5.541 real sec
[M::process] read 681154 sequences (100000016 bp) in 2.062 CPU sec, 2.107 real sec...
[M::mem_process_seqs] Processed 681484 reads in 117.604 CPU sec, 3.830 real sec
sorting block 23, #reads = 1080780 mem = 536882627 peak = 1082163200
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 281685, 9, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (124, 204, 365)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 847)
[M::mem_pestat] mean and std.dev: (227.12, 154.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1088)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 321, 446)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 916)
[M::mem_pestat] mean and std.dev: (339.16, 160.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1151)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (265, 356, 540)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1090)
[M::mem_pestat] mean and std.dev: (376.94, 173.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1365)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681202 sequences (100000090 bp) in 2.556 CPU sec, 2.869 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 281667, 9, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 190, 506)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1192)
[M::mem_pestat] mean and std.dev: (296.14, 192.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1535)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 323, 448)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 920)
[M::mem_pestat] mean and std.dev: (340.41, 161.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1156)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 383, 470)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 966)
[M::mem_pestat] mean and std.dev: (348.80, 164.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1214)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681210 reads in 171.642 CPU sec, 5.517 real sec
[M::process] read 681354 sequences (100000189 bp) in 1.982 CPU sec, 2.031 real sec...
sorting block 24, #reads = 1080304 mem = 536879119 peak = 1082163200
[M::mem_process_seqs] Processed 681154 reads in 118.975 CPU sec, 3.804 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 281418, 8, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 202, 387)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 857)
[M::mem_pestat] mean and std.dev: (243.64, 122.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1092)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 321, 446)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 916)
[M::mem_pestat] mean and std.dev: (338.99, 160.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1151)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 290, 496)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1078)
[M::mem_pestat] mean and std.dev: (303.64, 157.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1369)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 25, #reads = 1079164 mem = 536881032 peak = 1096671232
[M::process] read 681380 sequences (100000263 bp) in 2.658 CPU sec, 2.965 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (22, 281895, 7, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (247, 328, 472)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 922)
[M::mem_pestat] mean and std.dev: (336.84, 215.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1199)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 320, 445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 915)
[M::mem_pestat] mean and std.dev: (338.15, 160.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1150)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 288, 902)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2350)
[M::mem_pestat] mean and std.dev: (456.55, 316.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3074)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681768 sequences (100000086 bp) in 1.967 CPU sec, 1.981 real sec...
[M::mem_process_seqs] Processed 681202 reads in 171.351 CPU sec, 5.584 real sec
[M::mem_process_seqs] Processed 681354 reads in 117.837 CPU sec, 3.861 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 281383, 3, 17)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 235, 722)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1856)
[M::mem_pestat] mean and std.dev: (379.09, 346.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2423)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 316, 440)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 902)
[M::mem_pestat] mean and std.dev: (334.86, 158.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1133)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 232, 255)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (39, 399)
[M::mem_pestat] mean and std.dev: (216.00, 36.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 471)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 26, #reads = 1080266 mem = 536878040 peak = 1096671232
[M::process] read 681644 sequences (100000108 bp) in 2.661 CPU sec, 3.122 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 281715, 0, 24)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (120, 245, 372)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 876)
[M::mem_pestat] mean and std.dev: (260.86, 158.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1128)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 317, 442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 908)
[M::mem_pestat] mean and std.dev: (335.93, 160.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1141)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 246, 312)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 542)
[M::mem_pestat] mean and std.dev: (234.10, 58.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 657)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681380 reads in 172.064 CPU sec, 5.689 real sec
[M::process] read 681476 sequences (100000119 bp) in 1.885 CPU sec, 1.902 real sec...
[M::mem_process_seqs] Processed 681768 reads in 120.566 CPU sec, 4.023 real sec
sorting block 27, #reads = 1078883 mem = 536878706 peak = 1096671232
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 281848, 2, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 182, 268)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 506)
[M::mem_pestat] mean and std.dev: (222.28, 94.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 625)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 317, 443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 911)
[M::mem_pestat] mean and std.dev: (335.93, 159.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1145)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 409, 2258)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6456)
[M::mem_pestat] mean and std.dev: (495.42, 583.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8555)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681528 sequences (100000194 bp) in 2.761 CPU sec, 3.086 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 281954, 3, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 238, 414)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 906)
[M::mem_pestat] mean and std.dev: (266.25, 120.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1152)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 316, 441)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 905)
[M::mem_pestat] mean and std.dev: (335.27, 158.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1137)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (242, 348, 351)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (24, 569)
[M::mem_pestat] mean and std.dev: (313.44, 99.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 710)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681644 reads in 173.611 CPU sec, 5.740 real sec
[M::process] read 681142 sequences (100000036 bp) in 1.894 CPU sec, 2.019 real sec...
[M::mem_process_seqs] Processed 681476 reads in 121.557 CPU sec, 4.069 real sec
sorting block 28, #reads = 1078997 mem = 536880380 peak = 1096671232
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 282199, 11, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 306, 466)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1006)
[M::mem_pestat] mean and std.dev: (322.44, 153.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1276)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 317, 439)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 899)
[M::mem_pestat] mean and std.dev: (334.46, 157.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1129)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (39, 276, 1442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4248)
[M::mem_pestat] mean and std.dev: (1008.55, 1399.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6607)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 276, 637)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1581)
[M::mem_pestat] mean and std.dev: (322.22, 194.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2053)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 681326 sequences (100000181 bp) in 2.614 CPU sec, 2.987 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23, 281936, 14, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 216, 258)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 430)
[M::mem_pestat] mean and std.dev: (197.80, 75.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 516)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 317, 441)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 903)
[M::mem_pestat] mean and std.dev: (335.60, 158.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1134)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (39, 1010, 1979)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5859)
[M::mem_pestat] mean and std.dev: (635.55, 779.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7799)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (253, 436, 511)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1027)
[M::mem_pestat] mean and std.dev: (371.47, 184.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1285)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681528 reads in 171.105 CPU sec, 5.637 real sec
[M::process] read 681364 sequences (100000106 bp) in 2.030 CPU sec, 2.204 real sec...
sorting block 29, #reads = 1078829 mem = 536878032 peak = 1096671232
[M::mem_process_seqs] Processed 681142 reads in 118.816 CPU sec, 3.930 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20, 282196, 2, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 186, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 667)
[M::mem_pestat] mean and std.dev: (222.44, 130.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 840)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 316, 439)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 897)
[M::mem_pestat] mean and std.dev: (334.35, 157.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1126)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 221, 418)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 884)
[M::mem_pestat] mean and std.dev: (242.82, 104.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1117)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 30, #reads = 1078830 mem = 536878304 peak = 1096671232
[M::process] read 681184 sequences (100000195 bp) in 2.490 CPU sec, 2.713 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 282381, 5, 23)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 233, 523)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1273)
[M::mem_pestat] mean and std.dev: (283.29, 178.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1648)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 317, 439)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 895)
[M::mem_pestat] mean and std.dev: (335.21, 157.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1123)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 211, 348)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 746)
[M::mem_pestat] mean and std.dev: (212.85, 81.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 945)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680784 sequences (100000148 bp) in 1.950 CPU sec, 1.995 real sec...
[M::mem_process_seqs] Processed 681326 reads in 169.575 CPU sec, 5.602 real sec
[M::mem_process_seqs] Processed 681364 reads in 118.592 CPU sec, 3.940 real sec
sorting block 31, #reads = 1079215 mem = 536886428 peak = 1096671232
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (19, 281798, 3, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 191, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 651)
[M::mem_pestat] mean and std.dev: (220.56, 116.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 814)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 320, 444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 910)
[M::mem_pestat] mean and std.dev: (337.63, 159.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1143)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 204, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 798)
[M::mem_pestat] mean and std.dev: (245.90, 122.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1018)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680658 sequences (100000122 bp) in 2.591 CPU sec, 3.006 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 281798, 9, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 308, 420)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 926)
[M::mem_pestat] mean and std.dev: (302.00, 173.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1179)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 321, 443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 905)
[M::mem_pestat] mean and std.dev: (338.19, 158.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1136)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 247, 384)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 730)
[M::mem_pestat] mean and std.dev: (259.36, 94.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 903)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681184 reads in 171.383 CPU sec, 5.640 real sec
[M::process] read 680852 sequences (100000274 bp) in 1.918 CPU sec, 2.019 real sec...
[M::mem_process_seqs] Processed 680784 reads in 119.021 CPU sec, 3.918 real sec
sorting block 32, #reads = 1078038 mem = 536881676 peak = 1096671232
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 281344, 5, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 307, 477)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1137)
[M::mem_pestat] mean and std.dev: (354.15, 310.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1595)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 322, 444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 906)
[M::mem_pestat] mean and std.dev: (338.92, 158.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1137)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 232, 345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 671)
[M::mem_pestat] mean and std.dev: (238.81, 127.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 834)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680548 sequences (100000019 bp) in 2.602 CPU sec, 2.828 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 282040, 2, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 226, 442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 946)
[M::mem_pestat] mean and std.dev: (238.84, 105.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1198)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 319, 441)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 899)
[M::mem_pestat] mean and std.dev: (337.04, 158.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1128)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 253, 392)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 750)
[M::mem_pestat] mean and std.dev: (297.72, 116.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 929)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680658 reads in 168.169 CPU sec, 5.464 real sec
[M::process] read 680328 sequences (100000298 bp) in 2.042 CPU sec, 2.168 real sec...
[M::mem_process_seqs] Processed 680852 reads in 118.389 CPU sec, 3.820 real sec
sorting block 33, #reads = 1078146 mem = 536879992 peak = 1096671232
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 281923, 12, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 539, 1324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3632)
[M::mem_pestat] mean and std.dev: (607.97, 503.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4786)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 322, 443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 901)
[M::mem_pestat] mean and std.dev: (338.74, 158.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1130)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (286, 286, 374)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (110, 550)
[M::mem_pestat] mean and std.dev: (336.64, 64.85)
[M::mem_pestat] low and high boundaries for proper pairs: (22, 638)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (232, 275, 463)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 925)
[M::mem_pestat] mean and std.dev: (278.32, 108.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1156)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 679794 sequences (100000029 bp) in 2.554 CPU sec, 2.907 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 281879, 2, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (142, 307, 667)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1717)
[M::mem_pestat] mean and std.dev: (400.12, 265.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2242)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 323, 443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 897)
[M::mem_pestat] mean and std.dev: (339.52, 157.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1124)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 244, 513)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1209)
[M::mem_pestat] mean and std.dev: (316.31, 204.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1557)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680548 reads in 166.552 CPU sec, 5.361 real sec
[M::process] read 679784 sequences (100000173 bp) in 1.850 CPU sec, 1.859 real sec...
sorting block 34, #reads = 1078597 mem = 536878660 peak = 1096671232
[M::mem_process_seqs] Processed 680328 reads in 116.287 CPU sec, 3.708 real sec
sorting block 35, #reads = 1079102 mem = 536878981 peak = 1113317376
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 281694, 2, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 309, 570)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1398)
[M::mem_pestat] mean and std.dev: (331.42, 219.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1812)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 327, 450)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 914)
[M::mem_pestat] mean and std.dev: (343.73, 160.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1146)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 255, 439)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 993)
[M::mem_pestat] mean and std.dev: (258.08, 135.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1270)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 683938 sequences (100000140 bp) in 2.502 CPU sec, 2.706 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 281815, 3, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 229, 467)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1009)
[M::mem_pestat] mean and std.dev: (337.92, 254.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1354)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 330, 454)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 926)
[M::mem_pestat] mean and std.dev: (346.31, 161.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1162)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (314, 356, 489)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 839)
[M::mem_pestat] mean and std.dev: (353.08, 111.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1014)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 684090 sequences (100000071 bp) in 1.960 CPU sec, 1.968 real sec...
[M::mem_process_seqs] Processed 679794 reads in 165.952 CPU sec, 5.293 real sec
[M::mem_process_seqs] Processed 679784 reads in 114.491 CPU sec, 3.634 real sec
sorting block 36, #reads = 1077367 mem = 536878772 peak = 1113317376
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 282854, 8, 23)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (257, 276, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (127, 452)
[M::mem_pestat] mean and std.dev: (285.91, 52.14)
[M::mem_pestat] low and high boundaries for proper pairs: (62, 517)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 305, 427)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 879)
[M::mem_pestat] mean and std.dev: (324.58, 155.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1105)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 518, 534)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1258)
[M::mem_pestat] mean and std.dev: (368.32, 178.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1620)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 683664 sequences (100000078 bp) in 2.691 CPU sec, 2.861 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 283077, 9, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (131, 241, 321)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 701)
[M::mem_pestat] mean and std.dev: (239.49, 109.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 891)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 303, 423)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 871)
[M::mem_pestat] mean and std.dev: (321.84, 153.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1095)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 272, 391)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 725)
[M::mem_pestat] mean and std.dev: (281.83, 124.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 892)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 683216 sequences (100000135 bp) in 1.857 CPU sec, 1.877 real sec...
[M::mem_process_seqs] Processed 683938 reads in 169.534 CPU sec, 5.414 real sec
[M::mem_process_seqs] Processed 684090 reads in 118.580 CPU sec, 3.788 real sec
sorting block 37, #reads = 1078449 mem = 536877107 peak = 1113317376
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20, 283027, 1, 20)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (119, 226, 315)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 707)
[M::mem_pestat] mean and std.dev: (217.11, 136.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 903)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 306, 425)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 871)
[M::mem_pestat] mean and std.dev: (323.48, 152.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1094)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 223, 314)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 554)
[M::mem_pestat] mean and std.dev: (236.28, 66.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 674)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682752 sequences (100000301 bp) in 2.738 CPU sec, 2.835 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (18, 282122, 6, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (138, 207, 551)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1377)
[M::mem_pestat] mean and std.dev: (270.81, 165.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1790)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 309, 429)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 879)
[M::mem_pestat] mean and std.dev: (326.51, 154.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1104)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 343, 459)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 941)
[M::mem_pestat] mean and std.dev: (335.27, 173.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1182)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682512 sequences (100000153 bp) in 1.953 CPU sec, 1.958 real sec...
[M::mem_process_seqs] Processed 683664 reads in 169.898 CPU sec, 5.413 real sec
sorting block 38, #reads = 1080117 mem = 536879778 peak = 1113317376
[M::mem_process_seqs] Processed 683216 reads in 116.895 CPU sec, 3.706 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 282377, 8, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 360, 374)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 714)
[M::mem_pestat] mean and std.dev: (278.58, 109.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 884)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 311, 432)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 886)
[M::mem_pestat] mean and std.dev: (328.40, 154.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1113)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 290, 456)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1028)
[M::mem_pestat] mean and std.dev: (311.53, 204.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1314)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682066 sequences (100000056 bp) in 2.565 CPU sec, 3.123 real sec...
sorting block 39, #reads = 1080472 mem = 536882998 peak = 1113317376
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (22, 282242, 4, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 235, 326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 666)
[M::mem_pestat] mean and std.dev: (225.79, 93.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 836)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 313, 434)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 888)
[M::mem_pestat] mean and std.dev: (329.80, 154.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1115)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (245, 373, 468)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 914)
[M::mem_pestat] mean and std.dev: (402.70, 239.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1360)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682752 reads in 170.666 CPU sec, 5.594 real sec
[M::process] read 681720 sequences (100000141 bp) in 1.947 CPU sec, 2.119 real sec...
[M::mem_process_seqs] Processed 682512 reads in 120.216 CPU sec, 3.950 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 282216, 2, 23)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (125, 204, 426)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1028)
[M::mem_pestat] mean and std.dev: (259.00, 161.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1329)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 315, 434)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 886)
[M::mem_pestat] mean and std.dev: (331.01, 154.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1112)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 327, 697)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1763)
[M::mem_pestat] mean and std.dev: (373.55, 332.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2296)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 40, #reads = 1079446 mem = 536878065 peak = 1113317376
[M::process] read 681606 sequences (100000073 bp) in 2.497 CPU sec, 3.185 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 281611, 5, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 311, 984)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2570)
[M::mem_pestat] mean and std.dev: (412.27, 310.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3363)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 317, 436)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 888)
[M::mem_pestat] mean and std.dev: (332.44, 154.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1114)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 401, 689)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1685)
[M::mem_pestat] mean and std.dev: (373.93, 195.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2183)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682066 reads in 170.496 CPU sec, 5.627 real sec
[M::process] read 681394 sequences (100000242 bp) in 2.067 CPU sec, 2.116 real sec...
[M::mem_process_seqs] Processed 681720 reads in 118.875 CPU sec, 3.981 real sec
sorting block 41, #reads = 1079305 mem = 536879259 peak = 1113317376
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23, 282464, 3, 21)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 203, 274)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (37, 432)
[M::mem_pestat] mean and std.dev: (204.63, 57.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 511)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 318, 438)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 892)
[M::mem_pestat] mean and std.dev: (334.08, 155.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1119)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 243, 439)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 945)
[M::mem_pestat] mean and std.dev: (304.57, 167.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1198)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681300 sequences (100000107 bp) in 2.607 CPU sec, 3.052 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (18, 281789, 9, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 240, 376)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 830)
[M::mem_pestat] mean and std.dev: (227.88, 100.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1057)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 320, 440)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 896)
[M::mem_pestat] mean and std.dev: (335.55, 156.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1124)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 226, 351)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 757)
[M::mem_pestat] mean and std.dev: (261.50, 134.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 960)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681606 reads in 170.291 CPU sec, 5.643 real sec
[M::mem_process_seqs] Processed 681394 reads in 118.921 CPU sec, 3.959 real sec
[M::process] read 680994 sequences (100000038 bp) in 1.961 CPU sec, 2.137 real sec...
sorting block 42, #reads = 1079111 mem = 536883714 peak = 1113317376
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23, 281475, 3, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 241, 283)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (10, 465)
[M::mem_pestat] mean and std.dev: (219.65, 66.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 556)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 321, 443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 905)
[M::mem_pestat] mean and std.dev: (337.45, 157.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1136)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (266, 319, 510)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 998)
[M::mem_pestat] mean and std.dev: (354.71, 150.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1242)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680842 sequences (100000278 bp) in 2.351 CPU sec, 2.917 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (22, 281874, 6, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 222, 258)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 448)
[M::mem_pestat] mean and std.dev: (217.81, 62.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 543)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 322, 444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 906)
[M::mem_pestat] mean and std.dev: (338.19, 157.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1137)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 262, 575)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1365)
[M::mem_pestat] mean and std.dev: (297.34, 169.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1760)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681300 reads in 171.373 CPU sec, 5.695 real sec
[M::process] read 681320 sequences (100000223 bp) in 2.175 CPU sec, 2.388 real sec...
sorting block 43, #reads = 1078777 mem = 536879258 peak = 1113317376
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 281615, 3, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (250, 263, 394)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 682)
[M::mem_pestat] mean and std.dev: (251.20, 92.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 826)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 323, 445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 909)
[M::mem_pestat] mean and std.dev: (338.53, 157.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1141)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 361, 1283)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3463)
[M::mem_pestat] mean and std.dev: (549.74, 616.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4553)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680842 reads in 98.884 CPU sec, 3.204 real sec
[M::process] read 680980 sequences (100000151 bp) in 2.302 CPU sec, 2.435 real sec...
sorting block 44, #reads = 1079452 mem = 536884190 peak = 1113317376
[M::mem_process_seqs] Processed 680994 reads in 258.424 CPU sec, 8.485 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 281648, 5, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 261, 318)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 616)
[M::mem_pestat] mean and std.dev: (239.78, 96.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 765)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 321, 444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 908)
[M::mem_pestat] mean and std.dev: (338.07, 158.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1140)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 246, 372)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 810)
[M::mem_pestat] mean and std.dev: (278.80, 164.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1029)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681200 sequences (100000064 bp) in 2.584 CPU sec, 3.116 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 281347, 5, 13)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (134, 210, 408)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 956)
[M::mem_pestat] mean and std.dev: (271.85, 188.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1230)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 319, 441)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 901)
[M::mem_pestat] mean and std.dev: (336.17, 157.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1131)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 262, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 698)
[M::mem_pestat] mean and std.dev: (295.54, 139.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 867)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681320 reads in 195.450 CPU sec, 6.408 real sec
[M::mem_process_seqs] Processed 680980 reads in 120.905 CPU sec, 3.956 real sec
[M::process] read 681412 sequences (100000131 bp) in 2.007 CPU sec, 2.201 real sec...
sorting block 45, #reads = 1079344 mem = 536878895 peak = 1113317376
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23, 281174, 2, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 399, 417)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 789)
[M::mem_pestat] mean and std.dev: (327.74, 132.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 975)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 317, 440)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 900)
[M::mem_pestat] mean and std.dev: (334.90, 157.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1130)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 271, 401)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 835)
[M::mem_pestat] mean and std.dev: (302.55, 207.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1131)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 46, #reads = 1078885 mem = 536877966 peak = 1141809152
[M::process] read 681400 sequences (100000059 bp) in 2.544 CPU sec, 3.051 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 281833, 3, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 236, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 577)
[M::mem_pestat] mean and std.dev: (279.03, 136.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 825)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 318, 441)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 905)
[M::mem_pestat] mean and std.dev: (335.29, 157.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1137)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 292, 598)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1366)
[M::mem_pestat] mean and std.dev: (364.74, 239.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1750)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681200 reads in 173.079 CPU sec, 5.681 real sec
[M::mem_process_seqs] Processed 681412 reads in 120.513 CPU sec, 3.893 real sec
[M::process] read 681380 sequences (100000199 bp) in 2.066 CPU sec, 2.179 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 280897, 2, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 184, 214)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (13, 348)
[M::mem_pestat] mean and std.dev: (175.95, 47.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 415)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 316, 439)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 899)
[M::mem_pestat] mean and std.dev: (334.22, 157.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1129)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 243, 302)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 586)
[M::mem_pestat] mean and std.dev: (222.36, 81.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 728)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 47, #reads = 1078233 mem = 536877260 peak = 1141809152
[M::process] read 681072 sequences (100000264 bp) in 2.662 CPU sec, 2.830 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23, 281470, 3, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 272, 381)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 801)
[M::mem_pestat] mean and std.dev: (246.60, 145.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1011)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 316, 438)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 894)
[M::mem_pestat] mean and std.dev: (333.99, 156.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1122)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 262, 405)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 865)
[M::mem_pestat] mean and std.dev: (264.38, 129.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1095)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681400 reads in 173.152 CPU sec, 5.534 real sec
[M::process] read 680992 sequences (100000179 bp) in 1.951 CPU sec, 1.963 real sec...
[M::mem_process_seqs] Processed 681380 reads in 119.569 CPU sec, 3.798 real sec
sorting block 48, #reads = 1079012 mem = 536878596 peak = 1141809152
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 281866, 2, 24)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 429, 539)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1203)
[M::mem_pestat] mean and std.dev: (441.64, 316.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1707)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 318, 440)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 898)
[M::mem_pestat] mean and std.dev: (335.18, 157.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1127)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 248, 378)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 736)
[M::mem_pestat] mean and std.dev: (260.73, 101.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 915)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680940 sequences (100000139 bp) in 2.597 CPU sec, 2.701 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 281113, 5, 23)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 221, 341)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 667)
[M::mem_pestat] mean and std.dev: (194.33, 53.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 830)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 320, 441)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 901)
[M::mem_pestat] mean and std.dev: (336.33, 157.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1131)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 258, 429)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 961)
[M::mem_pestat] mean and std.dev: (318.74, 212.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1227)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680726 sequences (100000084 bp) in 1.971 CPU sec, 1.995 real sec...
[M::mem_process_seqs] Processed 681072 reads in 173.325 CPU sec, 5.526 real sec
[M::mem_process_seqs] Processed 680992 reads in 118.159 CPU sec, 3.763 real sec
sorting block 49, #reads = 1078825 mem = 536877272 peak = 1141809152
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 281558, 5, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 325, 432)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1000)
[M::mem_pestat] mean and std.dev: (294.68, 190.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1284)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 319, 442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 904)
[M::mem_pestat] mean and std.dev: (336.85, 158.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1135)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (240, 353, 586)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1278)
[M::mem_pestat] mean and std.dev: (387.62, 234.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1624)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680660 sequences (100000155 bp) in 2.692 CPU sec, 2.800 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 281663, 9, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (214, 277, 523)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1141)
[M::mem_pestat] mean and std.dev: (355.74, 191.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1450)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 320, 442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 900)
[M::mem_pestat] mean and std.dev: (337.02, 157.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1129)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 449, 1197)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3201)
[M::mem_pestat] mean and std.dev: (699.89, 732.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4203)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680572 sequences (100000147 bp) in 1.964 CPU sec, 1.971 real sec...
[M::mem_process_seqs] Processed 680940 reads in 171.621 CPU sec, 5.472 real sec
sorting block 50, #reads = 1078614 mem = 536879827 peak = 1141809152
[M::mem_process_seqs] Processed 680726 reads in 117.842 CPU sec, 3.743 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 281063, 8, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 195, 297)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 539)
[M::mem_pestat] mean and std.dev: (221.44, 82.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 660)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 321, 444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 908)
[M::mem_pestat] mean and std.dev: (338.07, 158.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1140)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 301, 492)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1040)
[M::mem_pestat] mean and std.dev: (366.42, 205.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1314)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 51, #reads = 1079317 mem = 536876787 peak = 1141809152
[M::process] read 680156 sequences (100000037 bp) in 2.517 CPU sec, 2.909 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 281070, 2, 57)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 208, 260)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (2, 432)
[M::mem_pestat] mean and std.dev: (207.07, 87.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 559)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 322, 445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 909)
[M::mem_pestat] mean and std.dev: (339.68, 159.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1141)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 303, 384)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 748)
[M::mem_pestat] mean and std.dev: (306.04, 126.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 930)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680058 sequences (100000010 bp) in 1.880 CPU sec, 1.924 real sec...
[M::mem_process_seqs] Processed 680660 reads in 174.009 CPU sec, 5.741 real sec
[M::mem_process_seqs] Processed 680572 reads in 119.962 CPU sec, 3.979 real sec
sorting block 52, #reads = 1078099 mem = 536878526 peak = 1141809152
[M::process] read 679926 sequences (100000030 bp) in 2.586 CPU sec, 3.140 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 281430, 5, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 265, 306)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 586)
[M::mem_pestat] mean and std.dev: (228.61, 80.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 726)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 325, 448)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 912)
[M::mem_pestat] mean and std.dev: (342.27, 160.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1144)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 226, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 695)
[M::mem_pestat] mean and std.dev: (243.54, 108.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 871)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680058 reads in 96.795 CPU sec, 3.151 real sec
[M::process] read 679718 sequences (100000199 bp) in 1.881 CPU sec, 2.009 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 281363, 10, 20)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 302, 540)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1200)
[M::mem_pestat] mean and std.dev: (368.38, 223.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1530)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 323, 446)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 910)
[M::mem_pestat] mean and std.dev: (340.33, 159.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1142)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (788, 1069, 1069)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (226, 1631)
[M::mem_pestat] mean and std.dev: (975.33, 132.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1912)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 345, 422)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 874)
[M::mem_pestat] mean and std.dev: (294.10, 139.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1100)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 281230, 7, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (112, 175, 241)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 499)
[M::mem_pestat] mean and std.dev: (172.44, 59.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 628)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 327, 447)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 905)
[M::mem_pestat] mean and std.dev: (343.00, 159.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1134)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (173, 298, 509)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1181)
[M::mem_pestat] mean and std.dev: (316.98, 155.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1517)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680156 reads in 262.868 CPU sec, 8.559 real sec
sorting block 53, #reads = 1079851 mem = 536880006 peak = 1141809152
[M::process] read 682046 sequences (100000181 bp) in 2.024 CPU sec, 2.107 real sec...
[M::mem_process_seqs] Processed 679926 reads in 138.441 CPU sec, 4.519 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 281327, 12, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 276, 359)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 777)
[M::mem_pestat] mean and std.dev: (225.70, 93.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 986)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 327, 448)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 906)
[M::mem_pestat] mean and std.dev: (343.12, 158.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1135)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (692, 692, 846)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (384, 1154)
[M::mem_pestat] mean and std.dev: (730.50, 66.68)
[M::mem_pestat] low and high boundaries for proper pairs: (230, 1308)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (256, 283, 379)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (10, 625)
[M::mem_pestat] mean and std.dev: (273.26, 91.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 748)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 54, #reads = 1078919 mem = 536886001 peak = 1145552896
[M::process] read 684532 sequences (100000069 bp) in 2.654 CPU sec, 3.124 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20, 281183, 4, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 281, 300)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 520)
[M::mem_pestat] mean and std.dev: (247.85, 73.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 630)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 316, 438)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 896)
[M::mem_pestat] mean and std.dev: (333.68, 158.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1125)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 315, 383)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 757)
[M::mem_pestat] mean and std.dev: (304.41, 136.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 944)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 679718 reads in 167.925 CPU sec, 5.594 real sec
[M::mem_process_seqs] Processed 682046 reads in 121.172 CPU sec, 4.019 real sec
[M::process] read 683960 sequences (100000126 bp) in 2.042 CPU sec, 2.110 real sec...
sorting block 55, #reads = 1077942 mem = 536878730 peak = 1145552896
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 282845, 3, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (125, 329, 424)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1022)
[M::mem_pestat] mean and std.dev: (260.42, 127.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1321)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 302, 426)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 882)
[M::mem_pestat] mean and std.dev: (322.89, 156.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1110)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 359, 384)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 770)
[M::mem_pestat] mean and std.dev: (284.52, 129.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 963)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 683596 sequences (100000070 bp) in 2.295 CPU sec, 2.784 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (21, 282542, 8, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (245, 332, 632)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1406)
[M::mem_pestat] mean and std.dev: (424.00, 267.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1793)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 306, 431)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 893)
[M::mem_pestat] mean and std.dev: (326.72, 158.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1124)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (291, 445, 462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 804)
[M::mem_pestat] mean and std.dev: (387.05, 134.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 975)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 684532 reads in 168.230 CPU sec, 5.581 real sec
[M::mem_process_seqs] Processed 683960 reads in 117.952 CPU sec, 3.922 real sec
[M::process] read 683438 sequences (100000187 bp) in 2.176 CPU sec, 2.368 real sec...
sorting block 56, #reads = 1079240 mem = 536878440 peak = 1145552896
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (15, 282389, 10, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 179, 274)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 528)
[M::mem_pestat] mean and std.dev: (193.62, 89.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 655)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 309, 433)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 895)
[M::mem_pestat] mean and std.dev: (328.37, 158.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1126)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (39, 254, 2214)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6564)
[M::mem_pestat] mean and std.dev: (863.30, 1091.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8739)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 281, 456)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 938)
[M::mem_pestat] mean and std.dev: (308.12, 191.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1179)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682886 sequences (100000058 bp) in 2.378 CPU sec, 2.970 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (22, 282017, 2, 21)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (124, 247, 502)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1258)
[M::mem_pestat] mean and std.dev: (309.23, 183.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1636)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 311, 436)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 900)
[M::mem_pestat] mean and std.dev: (330.14, 158.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1132)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 307, 352)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 684)
[M::mem_pestat] mean and std.dev: (288.95, 107.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 850)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683596 reads in 172.366 CPU sec, 5.656 real sec
[M::mem_process_seqs] Processed 683438 reads in 121.052 CPU sec, 3.946 real sec
[M::process] read 682864 sequences (100000124 bp) in 2.196 CPU sec, 2.246 real sec...
sorting block 57, #reads = 1082472 mem = 536881342 peak = 1145552896
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 282082, 7, 19)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 311, 474)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1088)
[M::mem_pestat] mean and std.dev: (340.00, 219.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1395)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 313, 436)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 898)
[M::mem_pestat] mean and std.dev: (331.05, 158.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1129)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 233, 372)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 768)
[M::mem_pestat] mean and std.dev: (231.00, 86.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 966)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 58, #reads = 1082043 mem = 536879154 peak = 1154273280
[M::process] read 682384 sequences (100000054 bp) in 2.232 CPU sec, 2.758 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 282811, 2, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 265, 585)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1403)
[M::mem_pestat] mean and std.dev: (336.82, 221.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1812)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 314, 439)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 907)
[M::mem_pestat] mean and std.dev: (332.65, 159.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1141)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 216, 378)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 830)
[M::mem_pestat] mean and std.dev: (247.07, 135.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1056)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682886 reads in 172.234 CPU sec, 5.689 real sec
[M::process] read 682192 sequences (100000212 bp) in 1.965 CPU sec, 2.030 real sec...
[M::mem_process_seqs] Processed 682864 reads in 118.451 CPU sec, 3.911 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 281607, 3, 23)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 286, 651)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1587)
[M::mem_pestat] mean and std.dev: (326.61, 193.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2055)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 317, 441)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 907)
[M::mem_pestat] mean and std.dev: (334.54, 158.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1140)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (230, 300, 452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 896)
[M::mem_pestat] mean and std.dev: (316.24, 125.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1118)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 59, #reads = 1081604 mem = 536881511 peak = 1154273280
[M::process] read 681848 sequences (100000209 bp) in 2.627 CPU sec, 3.083 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 282018, 4, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 221, 446)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1000)
[M::mem_pestat] mean and std.dev: (295.35, 167.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1277)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 318, 443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 911)
[M::mem_pestat] mean and std.dev: (335.94, 159.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1145)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 264, 527)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1253)
[M::mem_pestat] mean and std.dev: (254.03, 146.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1616)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682384 reads in 170.349 CPU sec, 5.673 real sec
[M::mem_process_seqs] Processed 682192 reads in 118.587 CPU sec, 3.922 real sec
[M::process] read 682738 sequences (100000135 bp) in 2.085 CPU sec, 2.237 real sec...
sorting block 60, #reads = 1080260 mem = 536876615 peak = 1154273280
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 281752, 6, 21)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 204, 277)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 531)
[M::mem_pestat] mean and std.dev: (207.21, 66.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 658)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 318, 442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 908)
[M::mem_pestat] mean and std.dev: (335.55, 158.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1141)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 176, 399)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 933)
[M::mem_pestat] mean and std.dev: (258.35, 185.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1200)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681498 sequences (100000207 bp) in 2.236 CPU sec, 2.690 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (19, 281587, 7, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 217, 275)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 465)
[M::mem_pestat] mean and std.dev: (220.72, 53.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 560)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 312, 436)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 898)
[M::mem_pestat] mean and std.dev: (331.32, 158.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1129)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 307, 424)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 896)
[M::mem_pestat] mean and std.dev: (258.57, 115.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1132)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681848 reads in 171.738 CPU sec, 5.646 real sec
[M::process] read 681412 sequences (100000096 bp) in 2.004 CPU sec, 2.053 real sec...
[M::mem_process_seqs] Processed 682738 reads in 118.774 CPU sec, 3.887 real sec
sorting block 61, #reads = 1080381 mem = 536879386 peak = 1154273280
[M::process] read 681612 sequences (100000112 bp) in 2.433 CPU sec, 2.850 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 281779, 13, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (138, 175, 388)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 888)
[M::mem_pestat] mean and std.dev: (272.44, 212.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1138)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 320, 445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 913)
[M::mem_pestat] mean and std.dev: (337.89, 158.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1147)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (24, 39, 2659)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7929)
[M::mem_pestat] mean and std.dev: (1152.23, 1248.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10564)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (233, 401, 531)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1127)
[M::mem_pestat] mean and std.dev: (437.61, 295.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1618)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681412 reads in 99.496 CPU sec, 3.229 real sec
sorting block 62, #reads = 1079293 mem = 536879365 peak = 1154273280
[M::process] read 681520 sequences (100000269 bp) in 2.049 CPU sec, 2.432 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 281898, 3, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 241, 485)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1141)
[M::mem_pestat] mean and std.dev: (282.77, 163.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1469)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 320, 443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 909)
[M::mem_pestat] mean and std.dev: (337.22, 158.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1142)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (247, 275, 405)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 721)
[M::mem_pestat] mean and std.dev: (276.76, 94.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 879)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 281474, 4, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 205, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 663)
[M::mem_pestat] mean and std.dev: (253.88, 143.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 828)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 322, 445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 913)
[M::mem_pestat] mean and std.dev: (338.31, 159.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1147)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (241, 338, 532)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1114)
[M::mem_pestat] mean and std.dev: (366.46, 201.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1405)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681498 reads in 268.906 CPU sec, 8.872 real sec
[M::mem_process_seqs] Processed 681612 reads in 142.285 CPU sec, 4.768 real sec
[M::process] read 681274 sequences (100000002 bp) in 2.347 CPU sec, 2.619 real sec...
sorting block 63, #reads = 1078706 mem = 536877994 peak = 1154273280
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23, 281577, 11, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 181, 350)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 732)
[M::mem_pestat] mean and std.dev: (288.13, 204.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1104)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 320, 444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 910)
[M::mem_pestat] mean and std.dev: (336.77, 157.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1143)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (272, 616, 1146)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2894)
[M::mem_pestat] mean and std.dev: (680.09, 379.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3768)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (145, 269, 431)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1003)
[M::mem_pestat] mean and std.dev: (271.81, 128.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1289)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 681228 sequences (100000130 bp) in 2.349 CPU sec, 2.827 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 281597, 6, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 243, 354)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 674)
[M::mem_pestat] mean and std.dev: (255.37, 116.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 834)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 319, 440)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 900)
[M::mem_pestat] mean and std.dev: (335.40, 156.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1130)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 282, 453)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1051)
[M::mem_pestat] mean and std.dev: (302.76, 177.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1350)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681520 reads in 172.292 CPU sec, 5.701 real sec
[M::mem_process_seqs] Processed 681274 reads in 120.575 CPU sec, 3.973 real sec
[M::process] read 681222 sequences (100000069 bp) in 2.036 CPU sec, 2.187 real sec...
sorting block 64, #reads = 1079843 mem = 536878425 peak = 1154273280
[M::process] read 681420 sequences (100000147 bp) in 2.417 CPU sec, 2.845 real sec...
sorting block 65, #reads = 1079174 mem = 536877739 peak = 1154273280
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (14, 281604, 2, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 301, 876)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2332)
[M::mem_pestat] mean and std.dev: (410.54, 328.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3060)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 317, 441)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 903)
[M::mem_pestat] mean and std.dev: (335.22, 157.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1134)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (257, 306, 409)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 713)
[M::mem_pestat] mean and std.dev: (323.24, 107.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 865)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681222 reads in 101.985 CPU sec, 3.332 real sec
[M::process] read 681508 sequences (100000159 bp) in 2.092 CPU sec, 2.307 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (22, 281568, 1, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 252, 334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 708)
[M::mem_pestat] mean and std.dev: (250.60, 113.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 895)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 318, 442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 906)
[M::mem_pestat] mean and std.dev: (335.58, 157.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1138)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (297, 428, 488)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 870)
[M::mem_pestat] mean and std.dev: (352.10, 121.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1061)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (22, 280857, 9, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 236, 436)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 970)
[M::mem_pestat] mean and std.dev: (300.59, 160.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1237)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 317, 441)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 905)
[M::mem_pestat] mean and std.dev: (334.91, 157.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1137)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 304, 374)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 686)
[M::mem_pestat] mean and std.dev: (293.00, 106.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 842)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681228 reads in 272.414 CPU sec, 9.004 real sec
[M::mem_process_seqs] Processed 681420 reads in 144.287 CPU sec, 4.790 real sec
[M::process] read 681192 sequences (100000160 bp) in 2.439 CPU sec, 2.547 real sec...
sorting block 66, #reads = 1078968 mem = 536878827 peak = 1154273280
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 281844, 2, 22)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 324, 370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 724)
[M::mem_pestat] mean and std.dev: (323.03, 156.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 949)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 317, 438)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 896)
[M::mem_pestat] mean and std.dev: (334.17, 156.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1125)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 248, 546)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1304)
[M::mem_pestat] mean and std.dev: (321.62, 230.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1683)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681182 sequences (100000178 bp) in 2.314 CPU sec, 2.749 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 282025, 5, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 238, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 674)
[M::mem_pestat] mean and std.dev: (214.28, 88.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 846)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 317, 440)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 900)
[M::mem_pestat] mean and std.dev: (334.99, 157.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1130)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (283, 397, 547)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1075)
[M::mem_pestat] mean and std.dev: (354.88, 160.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1339)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681508 reads in 173.757 CPU sec, 5.781 real sec
sorting block 67, #reads = 1077065 mem = 536882581 peak = 1154273280
[M::mem_process_seqs] Processed 681192 reads in 119.738 CPU sec, 3.938 real sec
[M::process] read 680802 sequences (100000155 bp) in 2.278 CPU sec, 2.408 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 281418, 3, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (144, 196, 294)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 594)
[M::mem_pestat] mean and std.dev: (225.96, 136.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 770)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 317, 438)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 894)
[M::mem_pestat] mean and std.dev: (334.11, 156.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1122)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 306, 574)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1334)
[M::mem_pestat] mean and std.dev: (330.23, 175.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1714)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 68, #reads = 1078753 mem = 536882553 peak = 1154273280
[M::process] read 680606 sequences (100000187 bp) in 2.429 CPU sec, 2.855 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 281483, 0, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 226, 388)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 820)
[M::mem_pestat] mean and std.dev: (254.31, 114.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1036)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 320, 440)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 896)
[M::mem_pestat] mean and std.dev: (335.96, 155.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1124)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 298, 433)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 869)
[M::mem_pestat] mean and std.dev: (300.31, 119.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1087)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681182 reads in 174.715 CPU sec, 5.765 real sec
[M::process] read 680838 sequences (100000225 bp) in 2.106 CPU sec, 2.165 real sec...
[M::mem_process_seqs] Processed 680802 reads in 121.623 CPU sec, 3.971 real sec
sorting block 69, #reads = 1077637 mem = 536879757 peak = 1154273280
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23, 281441, 4, 22)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 195, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 761)
[M::mem_pestat] mean and std.dev: (231.91, 107.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 961)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 319, 440)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 896)
[M::mem_pestat] mean and std.dev: (335.99, 156.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1124)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 277, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 586)
[M::mem_pestat] mean and std.dev: (296.76, 127.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 808)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680598 sequences (100000256 bp) in 2.245 CPU sec, 2.974 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (22, 281934, 6, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (125, 194, 267)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 551)
[M::mem_pestat] mean and std.dev: (202.82, 73.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 693)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 318, 438)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 890)
[M::mem_pestat] mean and std.dev: (334.42, 154.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1116)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 297, 535)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1203)
[M::mem_pestat] mean and std.dev: (323.08, 168.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1537)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680606 reads in 170.009 CPU sec, 5.593 real sec
[M::mem_process_seqs] Processed 680838 reads in 118.591 CPU sec, 3.845 real sec
[M::process] read 680430 sequences (100000027 bp) in 2.145 CPU sec, 2.294 real sec...
sorting block 70, #reads = 1077423 mem = 536879166 peak = 1154273280
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 281732, 6, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 267, 575)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1403)
[M::mem_pestat] mean and std.dev: (392.31, 318.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1817)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 317, 435)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 881)
[M::mem_pestat] mean and std.dev: (333.45, 154.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1104)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 256, 565)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1271)
[M::mem_pestat] mean and std.dev: (295.00, 139.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1624)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680038 sequences (100000026 bp) in 2.441 CPU sec, 2.953 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 281416, 12, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 298, 357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 649)
[M::mem_pestat] mean and std.dev: (251.46, 91.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 795)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 321, 441)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 893)
[M::mem_pestat] mean and std.dev: (337.70, 156.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1119)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (475, 2012, 2326)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6028)
[M::mem_pestat] mean and std.dev: (1668.00, 1408.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7879)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 274, 395)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 785)
[M::mem_pestat] mean and std.dev: (279.96, 118.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 980)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680598 reads in 167.937 CPU sec, 5.598 real sec
[M::mem_process_seqs] Processed 680430 reads in 117.289 CPU sec, 3.851 real sec
sorting block 71, #reads = 1078032 mem = 536879368 peak = 1154273280
[M::process] read 679848 sequences (100000189 bp) in 2.292 CPU sec, 2.470 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23, 281208, 7, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (133, 227, 292)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 610)
[M::mem_pestat] mean and std.dev: (230.95, 113.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 769)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 325, 443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 895)
[M::mem_pestat] mean and std.dev: (339.86, 156.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1121)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (238, 293, 536)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1132)
[M::mem_pestat] mean and std.dev: (314.29, 144.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1430)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680120 sequences (100000121 bp) in 2.232 CPU sec, 2.680 real sec...
sorting block 72, #reads = 1079088 mem = 536877825 peak = 1154273280
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 281225, 7, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 395, 429)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 925)
[M::mem_pestat] mean and std.dev: (307.10, 178.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1173)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 328, 449)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 913)
[M::mem_pestat] mean and std.dev: (343.25, 159.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1145)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 314, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 599)
[M::mem_pestat] mean and std.dev: (298.06, 108.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 733)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680038 reads in 166.883 CPU sec, 5.592 real sec
[M::mem_process_seqs] Processed 679848 reads in 116.543 CPU sec, 3.899 real sec
[M::process] read 688228 sequences (100000066 bp) in 2.288 CPU sec, 2.569 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 281948, 4, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (200, 279, 414)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 842)
[M::mem_pestat] mean and std.dev: (287.27, 121.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1056)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 327, 450)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 916)
[M::mem_pestat] mean and std.dev: (343.68, 160.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1149)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 275, 402)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 784)
[M::mem_pestat] mean and std.dev: (296.07, 124.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 975)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 73, #reads = 1077493 mem = 536879121 peak = 1154273280
[M::process] read 686490 sequences (100000091 bp) in 2.533 CPU sec, 2.986 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 284497, 6, 21)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 258, 374)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 752)
[M::mem_pestat] mean and std.dev: (251.23, 115.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 941)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 282, 412)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 866)
[M::mem_pestat] mean and std.dev: (309.76, 156.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1093)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (141, 231, 311)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 651)
[M::mem_pestat] mean and std.dev: (249.48, 130.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 821)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680120 reads in 176.381 CPU sec, 5.871 real sec
[M::mem_process_seqs] Processed 688228 reads in 126.622 CPU sec, 4.147 real sec
[M::process] read 685752 sequences (100000171 bp) in 2.269 CPU sec, 2.364 real sec...
sorting block 74, #reads = 1077339 mem = 536879568 peak = 1154273280
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (16, 283636, 9, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 243, 305)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 535)
[M::mem_pestat] mean and std.dev: (226.50, 80.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 650)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 292, 422)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 886)
[M::mem_pestat] mean and std.dev: (316.95, 157.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1118)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 277, 392)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 776)
[M::mem_pestat] mean and std.dev: (293.10, 116.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 968)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 685338 sequences (100000167 bp) in 2.171 CPU sec, 2.837 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 283762, 5, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 281, 378)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 758)
[M::mem_pestat] mean and std.dev: (256.09, 119.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 948)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 296, 425)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 889)
[M::mem_pestat] mean and std.dev: (320.27, 158.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1121)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 254, 335)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 641)
[M::mem_pestat] mean and std.dev: (260.30, 95.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 794)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 686490 reads in 178.167 CPU sec, 5.888 real sec
[M::process] read 684880 sequences (100000219 bp) in 2.105 CPU sec, 2.146 real sec...
[M::mem_process_seqs] Processed 685752 reads in 122.757 CPU sec, 4.004 real sec
sorting block 75, #reads = 1081051 mem = 536878768 peak = 1154273280
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 283637, 2, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 343, 403)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 899)
[M::mem_pestat] mean and std.dev: (281.35, 150.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1147)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 300, 426)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 888)
[M::mem_pestat] mean and std.dev: (321.89, 157.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1119)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 317, 538)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1262)
[M::mem_pestat] mean and std.dev: (373.68, 261.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1624)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 684260 sequences (100000184 bp) in 2.459 CPU sec, 3.167 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20, 283225, 8, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (130, 192, 332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 736)
[M::mem_pestat] mean and std.dev: (176.75, 79.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 938)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 302, 429)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 893)
[M::mem_pestat] mean and std.dev: (323.62, 157.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1125)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (143, 205, 297)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 605)
[M::mem_pestat] mean and std.dev: (214.21, 82.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 759)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 685338 reads in 176.641 CPU sec, 5.883 real sec
[M::process] read 683952 sequences (100000137 bp) in 2.066 CPU sec, 2.091 real sec...
sorting block 76, #reads = 1080784 mem = 536879526 peak = 1154273280
[M::mem_process_seqs] Processed 684880 reads in 121.329 CPU sec, 3.977 real sec
sorting block 77, #reads = 1080515 mem = 536879282 peak = 1154273280
[M::process] read 683360 sequences (100000072 bp) in 2.082 CPU sec, 2.376 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 283323, 11, 23)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (257, 343, 834)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1988)
[M::mem_pestat] mean and std.dev: (439.25, 314.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2565)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 309, 438)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 912)
[M::mem_pestat] mean and std.dev: (330.13, 160.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1149)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (427, 648, 864)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1738)
[M::mem_pestat] mean and std.dev: (548.80, 295.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2175)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 235, 296)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 536)
[M::mem_pestat] mean and std.dev: (230.71, 73.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 656)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 683002 sequences (100000131 bp) in 2.002 CPU sec, 2.078 real sec...
[M::mem_process_seqs] Processed 683952 reads in 105.679 CPU sec, 3.451 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 283030, 2, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (141, 230, 307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 639)
[M::mem_pestat] mean and std.dev: (227.86, 97.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 805)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 305, 433)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 903)
[M::mem_pestat] mean and std.dev: (326.51, 159.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1138)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 412, 2302)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6508)
[M::mem_pestat] mean and std.dev: (998.39, 1149.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8611)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (15, 282756, 6, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 187, 315)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 591)
[M::mem_pestat] mean and std.dev: (260.67, 131.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 786)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 312, 442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 922)
[M::mem_pestat] mean and std.dev: (332.53, 161.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1162)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (112, 173, 265)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 571)
[M::mem_pestat] mean and std.dev: (188.67, 85.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 724)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 684260 reads in 282.384 CPU sec, 9.359 real sec
[M::mem_process_seqs] Processed 683360 reads in 144.012 CPU sec, 4.772 real sec
[M::process] read 682820 sequences (100000274 bp) in 2.368 CPU sec, 2.923 real sec...
sorting block 78, #reads = 1079168 mem = 536877951 peak = 1154273280
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 282687, 9, 16)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 386, 451)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1039)
[M::mem_pestat] mean and std.dev: (321.88, 186.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1333)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 314, 443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 921)
[M::mem_pestat] mean and std.dev: (333.95, 161.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1160)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 197, 382)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 876)
[M::mem_pestat] mean and std.dev: (220.00, 131.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1123)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682928 sequences (100000066 bp) in 2.559 CPU sec, 3.093 real sec...
sorting block 79, #reads = 1078336 mem = 536879274 peak = 1172054016
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (22, 282387, 4, 23)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (104, 199, 424)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1064)
[M::mem_pestat] mean and std.dev: (218.58, 132.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1384)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 315, 444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 924)
[M::mem_pestat] mean and std.dev: (334.90, 161.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1164)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 245, 323)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 569)
[M::mem_pestat] mean and std.dev: (244.76, 67.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 692)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683002 reads in 176.223 CPU sec, 5.909 real sec
[M::mem_process_seqs] Processed 682820 reads in 124.109 CPU sec, 4.215 real sec
[M::process] read 682464 sequences (100000214 bp) in 1.962 CPU sec, 2.203 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 281976, 4, 20)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 264, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 641)
[M::mem_pestat] mean and std.dev: (244.58, 105.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 799)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 314, 442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 918)
[M::mem_pestat] mean and std.dev: (333.94, 160.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1156)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (149, 214, 287)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 563)
[M::mem_pestat] mean and std.dev: (204.42, 66.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 701)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 80, #reads = 1079001 mem = 536880290 peak = 1172054016
[M::process] read 682046 sequences (100000034 bp) in 2.317 CPU sec, 2.796 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 283022, 6, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 221, 503)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1195)
[M::mem_pestat] mean and std.dev: (285.13, 215.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1541)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 319, 448)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 930)
[M::mem_pestat] mean and std.dev: (337.35, 161.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1171)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 226, 539)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1293)
[M::mem_pestat] mean and std.dev: (390.72, 342.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1761)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682928 reads in 178.177 CPU sec, 5.917 real sec
[M::process] read 682360 sequences (100000072 bp) in 2.046 CPU sec, 2.180 real sec...
[M::mem_process_seqs] Processed 682464 reads in 125.010 CPU sec, 4.158 real sec
sorting block 81, #reads = 1077471 mem = 536881631 peak = 1172054016
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (21, 282023, 5, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (135, 228, 279)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 567)
[M::mem_pestat] mean and std.dev: (228.20, 123.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 722)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 319, 448)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 930)
[M::mem_pestat] mean and std.dev: (338.10, 162.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1171)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (239, 294, 459)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 899)
[M::mem_pestat] mean and std.dev: (275.20, 102.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1119)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681906 sequences (100000122 bp) in 2.547 CPU sec, 3.083 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20, 281773, 8, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 289, 3616)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10460)
[M::mem_pestat] mean and std.dev: (1083.00, 1464.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13882)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 317, 445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 921)
[M::mem_pestat] mean and std.dev: (336.08, 160.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1159)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 235, 277)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 575)
[M::mem_pestat] mean and std.dev: (218.52, 105.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 724)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681648 sequences (100000139 bp) in 1.819 CPU sec, 1.866 real sec...
[M::mem_process_seqs] Processed 682046 reads in 183.119 CPU sec, 5.982 real sec
[M::mem_process_seqs] Processed 682360 reads in 128.083 CPU sec, 4.214 real sec
sorting block 82, #reads = 1076881 mem = 536881715 peak = 1172054016
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 282227, 10, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (139, 177, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 811)
[M::mem_pestat] mean and std.dev: (205.45, 128.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1035)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 318, 446)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 922)
[M::mem_pestat] mean and std.dev: (336.85, 160.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1160)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (314, 484, 484)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 824)
[M::mem_pestat] mean and std.dev: (373.50, 160.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1016)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 235, 372)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 774)
[M::mem_pestat] mean and std.dev: (260.64, 117.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 975)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 681834 sequences (100000165 bp) in 2.603 CPU sec, 3.166 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (22, 281934, 4, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (130, 237, 271)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 553)
[M::mem_pestat] mean and std.dev: (212.15, 96.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 694)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 318, 446)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 922)
[M::mem_pestat] mean and std.dev: (337.04, 160.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1160)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 392, 542)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1172)
[M::mem_pestat] mean and std.dev: (358.61, 173.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1487)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681906 reads in 179.928 CPU sec, 5.917 real sec
[M::process] read 681792 sequences (100000153 bp) in 2.064 CPU sec, 2.109 real sec...
sorting block 83, #reads = 1077616 mem = 536879986 peak = 1172054016
[M::mem_process_seqs] Processed 681648 reads in 126.035 CPU sec, 4.104 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 282260, 8, 24)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (138, 185, 370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 834)
[M::mem_pestat] mean and std.dev: (217.38, 110.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1066)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 318, 445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 917)
[M::mem_pestat] mean and std.dev: (336.86, 159.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1153)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 214, 355)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 741)
[M::mem_pestat] mean and std.dev: (266.52, 143.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 934)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 84, #reads = 1075526 mem = 536882947 peak = 1180807168
[M::process] read 681958 sequences (100000117 bp) in 2.573 CPU sec, 3.131 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (19, 281917, 5, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 293, 473)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1055)
[M::mem_pestat] mean and std.dev: (279.53, 153.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1346)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 316, 442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 910)
[M::mem_pestat] mean and std.dev: (334.83, 158.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1144)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 301, 3993)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 11571)
[M::mem_pestat] mean and std.dev: (1415.97, 1922.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 15360)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681356 sequences (100000058 bp) in 2.007 CPU sec, 2.016 real sec...
[M::mem_process_seqs] Processed 681834 reads in 182.957 CPU sec, 6.026 real sec
[M::mem_process_seqs] Processed 681792 reads in 127.373 CPU sec, 4.151 real sec
sorting block 85, #reads = 1076448 mem = 536878661 peak = 1180807168
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 281589, 5, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 407, 925)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2313)
[M::mem_pestat] mean and std.dev: (555.04, 504.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3007)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 317, 443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 913)
[M::mem_pestat] mean and std.dev: (335.27, 159.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1148)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 219, 256)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (40, 400)
[M::mem_pestat] mean and std.dev: (221.77, 70.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 503)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681468 sequences (100000166 bp) in 2.688 CPU sec, 3.135 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 282140, 3, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 349, 497)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1057)
[M::mem_pestat] mean and std.dev: (309.54, 141.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1337)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 320, 446)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 918)
[M::mem_pestat] mean and std.dev: (337.94, 159.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1154)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 321, 475)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1057)
[M::mem_pestat] mean and std.dev: (307.00, 160.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1348)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681518 sequences (100000197 bp) in 1.966 CPU sec, 1.970 real sec...
[M::mem_process_seqs] Processed 681958 reads in 183.263 CPU sec, 5.925 real sec
[M::mem_process_seqs] Processed 681356 reads in 127.050 CPU sec, 4.093 real sec
sorting block 86, #reads = 1076100 mem = 536882724 peak = 1180807168
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23, 282127, 2, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (135, 304, 385)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 885)
[M::mem_pestat] mean and std.dev: (264.52, 137.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1135)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 318, 441)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 903)
[M::mem_pestat] mean and std.dev: (335.24, 157.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1134)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 276, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 738)
[M::mem_pestat] mean and std.dev: (268.54, 114.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 924)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681338 sequences (100000060 bp) in 2.769 CPU sec, 2.877 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 281864, 7, 22)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (142, 252, 428)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1000)
[M::mem_pestat] mean and std.dev: (260.61, 134.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1286)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 318, 441)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 905)
[M::mem_pestat] mean and std.dev: (334.80, 157.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1137)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 325, 478)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1164)
[M::mem_pestat] mean and std.dev: (251.50, 133.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1507)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681498 sequences (100000212 bp) in 2.040 CPU sec, 2.046 real sec...
[M::mem_process_seqs] Processed 681468 reads in 181.928 CPU sec, 5.778 real sec
sorting block 87, #reads = 1074892 mem = 536878534 peak = 1180807168
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (22, 281619, 2, 23)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 262, 469)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1073)
[M::mem_pestat] mean and std.dev: (336.19, 214.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1375)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 316, 436)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 888)
[M::mem_pestat] mean and std.dev: (332.91, 155.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1114)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 191, 306)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 546)
[M::mem_pestat] mean and std.dev: (205.80, 70.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 666)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681202 sequences (100000114 bp) in 2.180 CPU sec, 2.192 real sec...
[M::mem_process_seqs] Processed 681338 reads in 100.928 CPU sec, 3.193 real sec
[M::mem_process_seqs] Processed 681518 reads in 256.230 CPU sec, 8.150 real sec
sorting block 88, #reads = 1075405 mem = 536882811 peak = 1180807168
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 282370, 6, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (136, 209, 278)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 562)
[M::mem_pestat] mean and std.dev: (207.61, 72.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 704)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 316, 437)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 891)
[M::mem_pestat] mean and std.dev: (332.90, 155.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1118)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 291, 632)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1532)
[M::mem_pestat] mean and std.dev: (300.93, 256.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1982)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681244 sequences (100000121 bp) in 2.649 CPU sec, 2.760 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20, 281770, 6, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 234, 835)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2145)
[M::mem_pestat] mean and std.dev: (441.15, 384.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2800)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 317, 441)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 903)
[M::mem_pestat] mean and std.dev: (335.31, 157.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1134)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 317, 345)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 679)
[M::mem_pestat] mean and std.dev: (270.37, 111.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 846)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681296 sequences (100000156 bp) in 1.839 CPU sec, 1.848 real sec...
[M::mem_process_seqs] Processed 681498 reads in 202.338 CPU sec, 6.440 real sec
sorting block 89, #reads = 1076399 mem = 536877943 peak = 1180807168
[M::mem_process_seqs] Processed 681202 reads in 125.296 CPU sec, 3.974 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20, 281388, 1, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 294, 973)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2585)
[M::mem_pestat] mean and std.dev: (485.95, 515.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3391)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 318, 442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 904)
[M::mem_pestat] mean and std.dev: (335.96, 158.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1135)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 265, 490)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1092)
[M::mem_pestat] mean and std.dev: (342.39, 197.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1393)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 684144 sequences (100000228 bp) in 2.296 CPU sec, 2.511 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23, 282055, 3, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (103, 231, 769)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2101)
[M::mem_pestat] mean and std.dev: (387.77, 347.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2767)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 320, 445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 913)
[M::mem_pestat] mean and std.dev: (338.46, 160.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1147)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (280, 298, 361)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (118, 523)
[M::mem_pestat] mean and std.dev: (287.87, 87.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 637)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 688788 sequences (100000232 bp) in 2.059 CPU sec, 2.061 real sec...
[M::mem_process_seqs] Processed 681244 reads in 180.579 CPU sec, 5.740 real sec
sorting block 90, #reads = 1076181 mem = 536879376 peak = 1180807168
[M::mem_process_seqs] Processed 681296 reads in 123.566 CPU sec, 3.926 real sec
sorting block 91, #reads = 1076522 mem = 536880503 peak = 1190457344
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 283645, 9, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 223, 398)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 870)
[M::mem_pestat] mean and std.dev: (272.85, 174.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1106)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 305, 434)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 904)
[M::mem_pestat] mean and std.dev: (327.37, 160.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1139)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 257, 417)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 817)
[M::mem_pestat] mean and std.dev: (279.24, 106.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1017)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 687108 sequences (100000300 bp) in 2.803 CPU sec, 2.929 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20, 284336, 9, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (131, 200, 392)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 914)
[M::mem_pestat] mean and std.dev: (220.95, 144.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1175)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 279, 403)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 841)
[M::mem_pestat] mean and std.dev: (304.35, 151.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1060)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 228, 265)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 491)
[M::mem_pestat] mean and std.dev: (202.87, 61.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 604)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 686086 sequences (100000006 bp) in 2.022 CPU sec, 2.027 real sec...
[M::mem_process_seqs] Processed 684144 reads in 189.934 CPU sec, 6.038 real sec
[M::mem_process_seqs] Processed 688788 reads in 132.047 CPU sec, 4.192 real sec
sorting block 92, #reads = 1075339 mem = 536877785 peak = 1190457344
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (13, 284439, 2, 23)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 182, 1015)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2747)
[M::mem_pestat] mean and std.dev: (421.62, 457.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3613)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 286, 411)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 857)
[M::mem_pestat] mean and std.dev: (310.03, 152.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1080)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 221, 556)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1402)
[M::mem_pestat] mean and std.dev: (268.53, 179.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1825)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 685510 sequences (100000224 bp) in 2.504 CPU sec, 2.578 real sec...
[M::process] read 685824 sequences (100000203 bp) in 1.725 CPU sec, 1.728 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (16, 284142, 3, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (142, 202, 292)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 592)
[M::mem_pestat] mean and std.dev: (207.13, 87.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 742)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 293, 417)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 867)
[M::mem_pestat] mean and std.dev: (314.81, 153.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1092)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 304, 444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 916)
[M::mem_pestat] mean and std.dev: (318.79, 149.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1152)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 687108 reads in 186.636 CPU sec, 5.942 real sec
[M::mem_process_seqs] Processed 686086 reads in 125.566 CPU sec, 3.998 real sec
sorting block 93, #reads = 1077065 mem = 536884242 peak = 1190457344
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 283958, 0, 23)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (223, 418, 743)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1783)
[M::mem_pestat] mean and std.dev: (424.56, 247.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2303)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (194, 297, 423)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 881)
[M::mem_pestat] mean and std.dev: (318.68, 155.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1110)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 254, 287)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 503)
[M::mem_pestat] mean and std.dev: (208.11, 55.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 611)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 685686 sequences (100000228 bp) in 2.687 CPU sec, 2.787 real sec...
[M::process] read 685064 sequences (100000006 bp) in 1.730 CPU sec, 1.728 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 284009, 7, 13)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 334, 432)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 892)
[M::mem_pestat] mean and std.dev: (330.00, 153.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1122)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 295, 422)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 880)
[M::mem_pestat] mean and std.dev: (317.09, 153.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1109)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (259, 290, 441)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 805)
[M::mem_pestat] mean and std.dev: (312.00, 168.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 987)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 685510 reads in 180.935 CPU sec, 5.755 real sec
sorting block 94, #reads = 1078301 mem = 536881290 peak = 1190457344
[M::mem_process_seqs] Processed 685824 reads in 123.190 CPU sec, 3.913 real sec
sorting block 95, #reads = 1078283 mem = 536878200 peak = 1190457344
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 284114, 4, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (294, 394, 499)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 909)
[M::mem_pestat] mean and std.dev: (365.76, 148.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1114)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 296, 421)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 877)
[M::mem_pestat] mean and std.dev: (317.48, 153.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1105)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 408, 478)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1022)
[M::mem_pestat] mean and std.dev: (314.89, 138.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1294)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 684300 sequences (100000051 bp) in 2.560 CPU sec, 2.621 real sec...
[M::process] read 683970 sequences (100000027 bp) in 2.000 CPU sec, 2.004 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 283641, 2, 13)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 206, 271)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 517)
[M::mem_pestat] mean and std.dev: (200.96, 78.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 640)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 300, 427)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 889)
[M::mem_pestat] mean and std.dev: (322.02, 157.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1120)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 216, 304)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 528)
[M::mem_pestat] mean and std.dev: (220.58, 65.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 640)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 685686 reads in 186.572 CPU sec, 5.916 real sec
[M::mem_process_seqs] Processed 685064 reads in 128.932 CPU sec, 4.089 real sec
sorting block 96, #reads = 1076205 mem = 536879525 peak = 1190457344
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 284143, 2, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 224, 281)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (8, 463)
[M::mem_pestat] mean and std.dev: (229.46, 78.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 554)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 305, 432)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 898)
[M::mem_pestat] mean and std.dev: (325.64, 157.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1131)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 216, 273)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 487)
[M::mem_pestat] mean and std.dev: (206.71, 67.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 594)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 683676 sequences (100000004 bp) in 2.663 CPU sec, 2.723 real sec...
[M::process] read 683554 sequences (100000295 bp) in 1.570 CPU sec, 1.568 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (18, 283287, 2, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (129, 266, 311)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 675)
[M::mem_pestat] mean and std.dev: (233.50, 105.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 857)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 307, 435)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 905)
[M::mem_pestat] mean and std.dev: (326.90, 157.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1140)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 329, 351)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (30, 565)
[M::mem_pestat] mean and std.dev: (284.81, 66.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 672)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 684300 reads in 180.027 CPU sec, 5.708 real sec
[M::process] read 682726 sequences (100000290 bp) in 1.648 CPU sec, 1.656 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 283086, 4, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 226, 331)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 679)
[M::mem_pestat] mean and std.dev: (239.33, 108.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 853)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 309, 436)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 906)
[M::mem_pestat] mean and std.dev: (328.29, 157.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1141)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 246, 314)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 576)
[M::mem_pestat] mean and std.dev: (227.30, 55.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 707)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683676 reads in 100.930 CPU sec, 3.207 real sec
sorting block 97, #reads = 1078352 mem = 536878670 peak = 1190457344
[M::mem_process_seqs] Processed 683970 reads in 325.757 CPU sec, 10.374 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (21, 283287, 7, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 227, 302)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 504)
[M::mem_pestat] mean and std.dev: (207.71, 62.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 605)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 310, 438)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 912)
[M::mem_pestat] mean and std.dev: (329.78, 158.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1149)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 301, 349)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 687)
[M::mem_pestat] mean and std.dev: (251.05, 88.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 856)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 98, #reads = 1076783 mem = 536878312 peak = 1198604288
[M::process] read 682702 sequences (100000133 bp) in 2.702 CPU sec, 2.790 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 282616, 5, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 214, 285)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (9, 469)
[M::mem_pestat] mean and std.dev: (232.32, 79.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 561)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 313, 439)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 909)
[M::mem_pestat] mean and std.dev: (332.01, 159.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1144)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 235, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 683)
[M::mem_pestat] mean and std.dev: (285.72, 169.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 963)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682256 sequences (100000196 bp) in 1.589 CPU sec, 1.588 real sec...
[M::mem_process_seqs] Processed 683554 reads in 202.330 CPU sec, 6.433 real sec
[M::mem_process_seqs] Processed 682726 reads in 124.947 CPU sec, 3.960 real sec
sorting block 99, #reads = 1076902 mem = 536879839 peak = 1198604288
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 282719, 10, 20)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (233, 514, 528)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1118)
[M::mem_pestat] mean and std.dev: (433.32, 207.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1413)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 315, 444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 922)
[M::mem_pestat] mean and std.dev: (334.33, 160.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1161)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (696, 847, 847)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (394, 1149)
[M::mem_pestat] mean and std.dev: (790.89, 163.99)
[M::mem_pestat] low and high boundaries for proper pairs: (135, 1447)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 212, 350)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 724)
[M::mem_pestat] mean and std.dev: (217.82, 81.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 911)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 682310 sequences (100000194 bp) in 2.802 CPU sec, 2.898 real sec...
[M::process] read 682530 sequences (100000183 bp) in 2.050 CPU sec, 2.048 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 282271, 1, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 227, 263)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 473)
[M::mem_pestat] mean and std.dev: (204.61, 71.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 578)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 317, 445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 923)
[M::mem_pestat] mean and std.dev: (335.97, 160.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1162)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 257, 295)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 545)
[M::mem_pestat] mean and std.dev: (238.86, 92.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 670)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682702 reads in 183.781 CPU sec, 5.807 real sec
sorting block 100, #reads = 1074847 mem = 536878417 peak = 1198604288
[M::mem_process_seqs] Processed 682256 reads in 207.755 CPU sec, 6.588 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (21, 282763, 1, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 258, 372)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 786)
[M::mem_pestat] mean and std.dev: (275.25, 158.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 993)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 315, 444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 918)
[M::mem_pestat] mean and std.dev: (335.38, 160.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1155)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 363, 381)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 699)
[M::mem_pestat] mean and std.dev: (304.20, 122.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 858)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681970 sequences (100000032 bp) in 2.739 CPU sec, 2.800 real sec...
[M::process] read 682030 sequences (100000031 bp) in 2.060 CPU sec, 2.061 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 282733, 12, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 267, 402)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 790)
[M::mem_pestat] mean and std.dev: (296.41, 128.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 984)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 315, 445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 925)
[M::mem_pestat] mean and std.dev: (335.11, 161.34)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1165)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (942, 3456, 3456)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8484)
[M::mem_pestat] mean and std.dev: (2383.00, 1351.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10998)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (179, 204, 535)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1247)
[M::mem_pestat] mean and std.dev: (291.86, 159.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1603)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682310 reads in 181.677 CPU sec, 5.747 real sec
sorting block 101, #reads = 1075448 mem = 536877734 peak = 1198604288
[M::mem_process_seqs] Processed 682530 reads in 125.516 CPU sec, 3.999 real sec
sorting block 102, #reads = 1075996 mem = 536876647 peak = 1198604288
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 281920, 5, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 303, 769)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2009)
[M::mem_pestat] mean and std.dev: (367.73, 290.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2629)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 316, 444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 918)
[M::mem_pestat] mean and std.dev: (336.05, 161.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1155)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 262, 490)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1122)
[M::mem_pestat] mean and std.dev: (299.54, 164.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1438)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681874 sequences (100000215 bp) in 2.754 CPU sec, 2.814 real sec...
[M::process] read 681762 sequences (100000158 bp) in 2.030 CPU sec, 2.035 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 282200, 2, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 262, 295)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 575)
[M::mem_pestat] mean and std.dev: (214.05, 79.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 715)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 318, 445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 919)
[M::mem_pestat] mean and std.dev: (336.67, 160.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1156)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 189, 488)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1156)
[M::mem_pestat] mean and std.dev: (251.69, 143.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1490)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681970 reads in 180.139 CPU sec, 5.693 real sec
[M::mem_process_seqs] Processed 682030 reads in 202.462 CPU sec, 6.420 real sec
sorting block 103, #reads = 1076180 mem = 536878755 peak = 1198604288
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 282409, 3, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (218, 307, 485)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1019)
[M::mem_pestat] mean and std.dev: (363.83, 250.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1364)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 318, 446)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 920)
[M::mem_pestat] mean and std.dev: (337.35, 160.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1157)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (241, 289, 496)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1006)
[M::mem_pestat] mean and std.dev: (328.46, 181.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1261)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681852 sequences (100000244 bp) in 2.680 CPU sec, 2.742 real sec...
[M::process] read 681556 sequences (100000063 bp) in 1.830 CPU sec, 1.832 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 282431, 13, 19)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 277, 398)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 838)
[M::mem_pestat] mean and std.dev: (275.26, 129.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1058)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 320, 450)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 932)
[M::mem_pestat] mean and std.dev: (339.62, 162.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1173)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (327, 1782, 3692)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10422)
[M::mem_pestat] mean and std.dev: (2388.31, 2423.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13787)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 234, 564)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1362)
[M::mem_pestat] mean and std.dev: (230.53, 114.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1761)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681874 reads in 174.854 CPU sec, 5.538 real sec
[M::mem_process_seqs] Processed 681762 reads in 118.600 CPU sec, 3.763 real sec
sorting block 104, #reads = 1077377 mem = 536880624 peak = 1198604288
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 281669, 9, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (140, 178, 314)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 662)
[M::mem_pestat] mean and std.dev: (188.67, 73.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 836)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 320, 450)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 934)
[M::mem_pestat] mean and std.dev: (339.79, 163.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1176)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (288, 369, 846)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1962)
[M::mem_pestat] mean and std.dev: (556.81, 458.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2520)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681226 sequences (100000055 bp) in 2.611 CPU sec, 2.678 real sec...
[M::process] read 681166 sequences (100000144 bp) in 1.541 CPU sec, 1.544 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 281952, 6, 23)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 227, 314)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 636)
[M::mem_pestat] mean and std.dev: (243.69, 131.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 797)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 321, 452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 936)
[M::mem_pestat] mean and std.dev: (341.45, 164.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1178)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 249, 347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 663)
[M::mem_pestat] mean and std.dev: (273.57, 139.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 831)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681852 reads in 173.892 CPU sec, 5.522 real sec
sorting block 105, #reads = 1076854 mem = 536877750 peak = 1198604288
[M::mem_process_seqs] Processed 681556 reads in 118.670 CPU sec, 3.769 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 282013, 8, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (131, 192, 444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1070)
[M::mem_pestat] mean and std.dev: (252.92, 146.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1383)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 324, 455)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 943)
[M::mem_pestat] mean and std.dev: (344.00, 165.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1187)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 282, 367)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 759)
[M::mem_pestat] mean and std.dev: (228.67, 93.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 955)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681212 sequences (100000142 bp) in 2.632 CPU sec, 2.685 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (19, 282315, 5, 18)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 309, 1215)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3225)
[M::mem_pestat] mean and std.dev: (852.84, 999.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4851)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 324, 456)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 946)
[M::mem_pestat] mean and std.dev: (345.10, 167.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1191)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 297, 402)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 840)
[M::mem_pestat] mean and std.dev: (320.75, 178.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1059)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 683528 sequences (100000004 bp) in 2.160 CPU sec, 2.154 real sec...
[M::mem_process_seqs] Processed 681226 reads in 173.302 CPU sec, 5.479 real sec
sorting block 106, #reads = 1077040 mem = 536878563 peak = 1198604288
[M::mem_process_seqs] Processed 681166 reads in 119.825 CPU sec, 3.784 real sec
sorting block 107, #reads = 1075936 mem = 536886037 peak = 1198604288
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 282079, 3, 48)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 275, 393)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 855)
[M::mem_pestat] mean and std.dev: (277.21, 133.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1086)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 324, 458)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 952)
[M::mem_pestat] mean and std.dev: (345.67, 168.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1199)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 246, 285)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 495)
[M::mem_pestat] mean and std.dev: (245.36, 91.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 610)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 687072 sequences (100000037 bp) in 2.796 CPU sec, 2.844 real sec...
[M::process] read 685706 sequences (100000064 bp) in 2.023 CPU sec, 2.034 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 282598, 9, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 343, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 766)
[M::mem_pestat] mean and std.dev: (278.84, 156.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 969)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 308, 442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 924)
[M::mem_pestat] mean and std.dev: (332.15, 164.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1165)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 302, 493)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1077)
[M::mem_pestat] mean and std.dev: (325.14, 153.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1369)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681212 reads in 195.176 CPU sec, 6.176 real sec
[M::mem_process_seqs] Processed 683528 reads in 143.070 CPU sec, 4.558 real sec
sorting block 108, #reads = 1072852 mem = 536882317 peak = 1198604288
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 284644, 2, 20)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 222, 296)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 552)
[M::mem_pestat] mean and std.dev: (218.32, 71.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 680)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 290, 415)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 867)
[M::mem_pestat] mean and std.dev: (313.21, 154.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1093)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 186, 267)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 481)
[M::mem_pestat] mean and std.dev: (198.74, 73.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 588)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 684914 sequences (100000023 bp) in 2.741 CPU sec, 2.813 real sec...
[M::process] read 684716 sequences (100000114 bp) in 2.040 CPU sec, 2.044 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 283586, 7, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (134, 179, 293)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 611)
[M::mem_pestat] mean and std.dev: (195.80, 81.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 770)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 296, 422)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 880)
[M::mem_pestat] mean and std.dev: (317.87, 155.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1109)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 214, 521)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1237)
[M::mem_pestat] mean and std.dev: (223.69, 113.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1595)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 687072 reads in 175.105 CPU sec, 5.537 real sec
[M::mem_process_seqs] Processed 685706 reads in 118.974 CPU sec, 3.768 real sec
sorting block 109, #reads = 1072851 mem = 536875688 peak = 1198604288
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (21, 283262, 4, 20)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (134, 155, 385)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 887)
[M::mem_pestat] mean and std.dev: (213.95, 117.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1138)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 300, 423)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 875)
[M::mem_pestat] mean and std.dev: (320.17, 154.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1101)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (144, 238, 333)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 711)
[M::mem_pestat] mean and std.dev: (239.90, 130.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 900)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 684368 sequences (100000075 bp) in 2.793 CPU sec, 2.843 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 283775, 3, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 226, 467)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1055)
[M::mem_pestat] mean and std.dev: (333.32, 214.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1349)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 303, 427)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 885)
[M::mem_pestat] mean and std.dev: (322.97, 155.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1114)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 210, 304)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 644)
[M::mem_pestat] mean and std.dev: (207.63, 101.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 814)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 684266 sequences (100000024 bp) in 2.046 CPU sec, 2.049 real sec...
[M::mem_process_seqs] Processed 684914 reads in 172.755 CPU sec, 5.454 real sec
sorting block 110, #reads = 1079882 mem = 536882997 peak = 1198604288
[M::mem_process_seqs] Processed 684716 reads in 117.393 CPU sec, 3.715 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (18, 283310, 1, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (252, 334, 1038)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2610)
[M::mem_pestat] mean and std.dev: (554.94, 472.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3396)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 303, 427)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 885)
[M::mem_pestat] mean and std.dev: (322.77, 155.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1114)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 262, 378)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 722)
[M::mem_pestat] mean and std.dev: (272.31, 98.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 894)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 683626 sequences (100000060 bp) in 2.748 CPU sec, 2.788 real sec...
[M::process] read 683474 sequences (100000004 bp) in 2.028 CPU sec, 2.029 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (14, 283528, 3, 23)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (126, 313, 914)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2490)
[M::mem_pestat] mean and std.dev: (447.85, 432.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3278)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 303, 428)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 888)
[M::mem_pestat] mean and std.dev: (323.41, 155.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1118)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 278, 302)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (11, 496)
[M::mem_pestat] mean and std.dev: (245.60, 74.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 593)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 684368 reads in 174.429 CPU sec, 5.509 real sec
sorting block 111, #reads = 1079232 mem = 536879504 peak = 1198604288
[M::mem_process_seqs] Processed 684266 reads in 118.027 CPU sec, 3.741 real sec
sorting block 112, #reads = 1078490 mem = 536878866 peak = 1198604288
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (16, 282808, 7, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 393, 495)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1063)
[M::mem_pestat] mean and std.dev: (334.12, 162.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1347)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 309, 434)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 900)
[M::mem_pestat] mean and std.dev: (327.95, 157.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1133)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 321, 554)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1256)
[M::mem_pestat] mean and std.dev: (301.65, 141.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1607)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 683240 sequences (100000259 bp) in 2.709 CPU sec, 2.754 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 283132, 5, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 256, 370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 678)
[M::mem_pestat] mean and std.dev: (242.25, 86.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 832)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 310, 438)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 910)
[M::mem_pestat] mean and std.dev: (329.76, 158.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1146)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 394, 501)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1161)
[M::mem_pestat] mean and std.dev: (419.97, 286.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1566)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 683276 sequences (100000278 bp) in 2.018 CPU sec, 2.024 real sec...
[M::mem_process_seqs] Processed 683626 reads in 170.119 CPU sec, 5.382 real sec
[M::mem_process_seqs] Processed 683474 reads in 115.906 CPU sec, 3.655 real sec
sorting block 113, #reads = 1078958 mem = 536877009 peak = 1198604288
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 282559, 9, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (123, 342, 441)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1077)
[M::mem_pestat] mean and std.dev: (267.81, 138.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1395)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 312, 441)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 919)
[M::mem_pestat] mean and std.dev: (331.75, 159.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1158)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 305, 895)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2197)
[M::mem_pestat] mean and std.dev: (685.86, 644.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3264)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 683266 sequences (100000141 bp) in 2.514 CPU sec, 2.561 real sec...
[M::process] read 682874 sequences (100000142 bp) in 2.060 CPU sec, 2.052 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (19, 282519, 2, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 242, 377)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 815)
[M::mem_pestat] mean and std.dev: (264.28, 135.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1034)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 311, 438)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 908)
[M::mem_pestat] mean and std.dev: (330.21, 157.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1143)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (184, 243, 315)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 577)
[M::mem_pestat] mean and std.dev: (251.80, 95.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 708)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683240 reads in 187.532 CPU sec, 5.946 real sec
sorting block 114, #reads = 1078421 mem = 536879493 peak = 1198604288
[M::mem_process_seqs] Processed 683276 reads in 129.155 CPU sec, 4.100 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (22, 283265, 7, 22)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 283, 586)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1352)
[M::mem_pestat] mean and std.dev: (314.15, 181.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1735)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 312, 439)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 911)
[M::mem_pestat] mean and std.dev: (330.39, 157.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1147)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (151, 233, 366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 796)
[M::mem_pestat] mean and std.dev: (253.60, 145.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1011)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682606 sequences (100000212 bp) in 2.763 CPU sec, 2.811 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (22, 282983, 8, 22)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 327, 543)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1235)
[M::mem_pestat] mean and std.dev: (379.15, 220.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1581)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 314, 442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 918)
[M::mem_pestat] mean and std.dev: (333.07, 159.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1156)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (263, 312, 312)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (165, 410)
[M::mem_pestat] mean and std.dev: (284.00, 51.57)
[M::mem_pestat] low and high boundaries for proper pairs: (78, 490)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682476 sequences (100000096 bp) in 2.004 CPU sec, 2.012 real sec...
[M::mem_process_seqs] Processed 683266 reads in 173.564 CPU sec, 5.484 real sec
sorting block 115, #reads = 1077824 mem = 536879860 peak = 1198604288
[M::mem_process_seqs] Processed 682874 reads in 118.019 CPU sec, 3.734 real sec
sorting block 116, #reads = 1078770 mem = 536877408 peak = 1198604288
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20, 282276, 4, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (137, 208, 351)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 779)
[M::mem_pestat] mean and std.dev: (213.28, 93.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 993)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 315, 442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 916)
[M::mem_pestat] mean and std.dev: (333.75, 159.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1153)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 365, 477)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1031)
[M::mem_pestat] mean and std.dev: (407.94, 296.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1596)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681920 sequences (100000064 bp) in 2.764 CPU sec, 2.789 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (22, 282771, 5, 19)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 292, 346)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 724)
[M::mem_pestat] mean and std.dev: (235.17, 76.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 913)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 317, 443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 915)
[M::mem_pestat] mean and std.dev: (334.41, 158.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1151)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 255, 1286)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3428)
[M::mem_pestat] mean and std.dev: (536.79, 458.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4499)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681806 sequences (100000173 bp) in 2.048 CPU sec, 2.051 real sec...
[M::mem_process_seqs] Processed 682606 reads in 177.526 CPU sec, 5.616 real sec
[M::mem_process_seqs] Processed 682476 reads in 123.653 CPU sec, 3.914 real sec
sorting block 117, #reads = 1077304 mem = 536882951 peak = 1198604288
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 281769, 2, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (245, 300, 374)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 632)
[M::mem_pestat] mean and std.dev: (292.97, 87.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 761)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 319, 445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 917)
[M::mem_pestat] mean and std.dev: (336.51, 159.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1153)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 242, 306)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 576)
[M::mem_pestat] mean and std.dev: (234.85, 77.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 711)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681968 sequences (100000213 bp) in 2.760 CPU sec, 2.797 real sec...
[M::process] read 681712 sequences (100000012 bp) in 2.027 CPU sec, 2.030 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 281931, 4, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 168, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 646)
[M::mem_pestat] mean and std.dev: (220.77, 124.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 807)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 318, 444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 916)
[M::mem_pestat] mean and std.dev: (336.01, 158.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1152)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (168, 258, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 639)
[M::mem_pestat] mean and std.dev: (264.13, 133.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 797)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681920 reads in 177.752 CPU sec, 5.619 real sec
[M::mem_process_seqs] Processed 681806 reads in 121.353 CPU sec, 3.844 real sec
sorting block 118, #reads = 1075663 mem = 536878837 peak = 1198604288
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 281949, 1, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 324, 647)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1529)
[M::mem_pestat] mean and std.dev: (318.76, 203.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1970)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 316, 443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 915)
[M::mem_pestat] mean and std.dev: (334.89, 158.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1151)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (215, 284, 419)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 827)
[M::mem_pestat] mean and std.dev: (306.32, 151.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1031)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681668 sequences (100000006 bp) in 2.394 CPU sec, 2.442 real sec...
[M::process] read 682028 sequences (100000248 bp) in 1.620 CPU sec, 1.627 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 282051, 3, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 231, 369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 723)
[M::mem_pestat] mean and std.dev: (261.43, 85.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 900)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 317, 444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 914)
[M::mem_pestat] mean and std.dev: (335.64, 158.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1149)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (159, 230, 351)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 735)
[M::mem_pestat] mean and std.dev: (223.91, 86.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 927)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681968 reads in 176.920 CPU sec, 5.620 real sec
sorting block 119, #reads = 1076833 mem = 536880901 peak = 1198604288
[M::mem_process_seqs] Processed 681712 reads in 121.356 CPU sec, 3.866 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (19, 282351, 3, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 254, 450)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 988)
[M::mem_pestat] mean and std.dev: (277.71, 142.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1257)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 317, 443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 913)
[M::mem_pestat] mean and std.dev: (335.23, 158.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1148)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (150, 201, 469)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1107)
[M::mem_pestat] mean and std.dev: (249.23, 191.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1426)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682224 sequences (100000134 bp) in 2.770 CPU sec, 2.809 real sec...
[M::process] read 681714 sequences (100000064 bp) in 2.010 CPU sec, 2.012 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 282248, 5, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 266, 1184)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3192)
[M::mem_pestat] mean and std.dev: (573.20, 564.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4196)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 316, 444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 918)
[M::mem_pestat] mean and std.dev: (335.75, 160.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1155)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (218, 281, 406)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 782)
[M::mem_pestat] mean and std.dev: (314.85, 152.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 970)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681668 reads in 181.999 CPU sec, 5.757 real sec
sorting block 120, #reads = 1076638 mem = 536875605 peak = 1198604288
[M::mem_process_seqs] Processed 682028 reads in 127.523 CPU sec, 4.044 real sec
sorting block 121, #reads = 1074428 mem = 536883617 peak = 1198604288
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (15, 282263, 8, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (255, 309, 409)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 717)
[M::mem_pestat] mean and std.dev: (329.00, 163.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 982)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 314, 441)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 909)
[M::mem_pestat] mean and std.dev: (333.69, 158.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1143)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 234, 292)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 580)
[M::mem_pestat] mean and std.dev: (221.46, 99.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 724)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681888 sequences (100000007 bp) in 2.745 CPU sec, 2.772 real sec...
[M::process] read 681760 sequences (100000008 bp) in 1.570 CPU sec, 1.569 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (19, 281918, 2, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 264, 472)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1048)
[M::mem_pestat] mean and std.dev: (268.12, 150.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1336)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 317, 444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 916)
[M::mem_pestat] mean and std.dev: (336.17, 159.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1152)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 372, 512)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1124)
[M::mem_pestat] mean and std.dev: (365.90, 219.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1430)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682224 reads in 194.551 CPU sec, 6.186 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 282266, 4, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 229, 363)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 717)
[M::mem_pestat] mean and std.dev: (294.61, 172.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 984)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 317, 443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 913)
[M::mem_pestat] mean and std.dev: (335.38, 159.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1148)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (240, 359, 549)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1167)
[M::mem_pestat] mean and std.dev: (400.63, 210.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1476)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681696 sequences (100000046 bp) in 2.471 CPU sec, 2.476 real sec...
[M::mem_process_seqs] Processed 681888 reads in 103.342 CPU sec, 3.261 real sec
sorting block 122, #reads = 1072894 mem = 536878506 peak = 1198604288
[M::mem_process_seqs] Processed 681714 reads in 262.268 CPU sec, 8.343 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (17, 281870, 5, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (292, 312, 427)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (22, 697)
[M::mem_pestat] mean and std.dev: (311.33, 115.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 832)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 318, 446)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 922)
[M::mem_pestat] mean and std.dev: (336.95, 160.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1160)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 411, 457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1027)
[M::mem_pestat] mean and std.dev: (292.15, 149.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1312)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
sorting block 123, #reads = 1075652 mem = 536877976 peak = 1198604288
[M::process] read 681888 sequences (100000061 bp) in 2.185 CPU sec, 2.253 real sec...
[M::process] read 684246 sequences (100000089 bp) in 1.740 CPU sec, 1.745 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20, 282249, 10, 23)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 225, 402)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 842)
[M::mem_pestat] mean and std.dev: (284.16, 179.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1062)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 317, 445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 919)
[M::mem_pestat] mean and std.dev: (336.58, 160.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1156)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (5, 5, 5)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (5, 5)
[M::mem_pestat] mean and std.dev: (5.00, 0.00)
[M::mem_pestat] low and high boundaries for proper pairs: (5, 5)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (100, 236, 388)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 964)
[M::mem_pestat] mean and std.dev: (232.52, 124.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1252)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681760 reads in 205.109 CPU sec, 6.516 real sec
[M::mem_process_seqs] Processed 681696 reads in 127.243 CPU sec, 4.040 real sec
sorting block 124, #reads = 1073786 mem = 536878480 peak = 1198604288
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 282035, 4, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (217, 267, 284)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (83, 418)
[M::mem_pestat] mean and std.dev: (231.84, 52.91)
[M::mem_pestat] low and high boundaries for proper pairs: (16, 485)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (208, 318, 448)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 928)
[M::mem_pestat] mean and std.dev: (338.39, 163.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1168)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 331, 732)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1794)
[M::mem_pestat] mean and std.dev: (421.43, 291.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2325)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 689522 sequences (100000234 bp) in 2.872 CPU sec, 2.933 real sec...
[M::process] read 688078 sequences (100000078 bp) in 2.110 CPU sec, 2.108 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 282365, 6, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (138, 242, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 738)
[M::mem_pestat] mean and std.dev: (210.19, 87.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 938)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 304, 434)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 906)
[M::mem_pestat] mean and std.dev: (327.07, 160.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1142)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 248, 285)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 523)
[M::mem_pestat] mean and std.dev: (239.29, 79.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 642)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681888 reads in 202.575 CPU sec, 6.418 real sec
sorting block 125, #reads = 1071652 mem = 536877363 peak = 1198604288
[M::mem_process_seqs] Processed 684246 reads in 147.052 CPU sec, 4.668 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (21, 284937, 11, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 242, 500)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1120)
[M::mem_pestat] mean and std.dev: (308.25, 176.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1430)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 283, 407)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 849)
[M::mem_pestat] mean and std.dev: (306.37, 150.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1070)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1610, 1610, 6026)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 14858)
[M::mem_pestat] mean and std.dev: (2485.36, 2247.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 19274)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (235, 276, 729)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1717)
[M::mem_pestat] mean and std.dev: (412.81, 345.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2211)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 687214 sequences (100000283 bp) in 2.815 CPU sec, 2.867 real sec...
[M::process] read 686278 sequences (100000231 bp) in 2.070 CPU sec, 2.073 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 284981, 3, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (135, 173, 254)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 492)
[M::mem_pestat] mean and std.dev: (206.24, 115.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 670)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 273, 395)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 823)
[M::mem_pestat] mean and std.dev: (297.83, 146.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1037)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 383, 1134)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2962)
[M::mem_pestat] mean and std.dev: (485.32, 359.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3876)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 688078 reads in 185.763 CPU sec, 5.873 real sec
sorting block 126, #reads = 1067563 mem = 536877251 peak = 1198604288
[M::mem_process_seqs] Processed 689522 reads in 209.504 CPU sec, 6.645 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 284378, 9, 17)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 259, 645)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1529)
[M::mem_pestat] mean and std.dev: (374.48, 319.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1971)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 288, 413)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 861)
[M::mem_pestat] mean and std.dev: (310.78, 151.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1085)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 241, 407)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 879)
[M::mem_pestat] mean and std.dev: (273.29, 145.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1115)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 687028 sequences (100000205 bp) in 2.620 CPU sec, 2.684 real sec...
[M::process] read 687728 sequences (100000287 bp) in 2.149 CPU sec, 2.157 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (17, 284249, 4, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (112, 172, 274)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 598)
[M::mem_pestat] mean and std.dev: (189.75, 88.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 760)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 293, 418)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 870)
[M::mem_pestat] mean and std.dev: (314.66, 152.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1096)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 274, 616)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1444)
[M::mem_pestat] mean and std.dev: (357.86, 269.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1858)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 687214 reads in 182.610 CPU sec, 5.776 real sec
sorting block 127, #reads = 1076311 mem = 536878321 peak = 1198604288
[M::mem_process_seqs] Processed 686278 reads in 122.618 CPU sec, 3.880 real sec
sorting block 128, #reads = 1077040 mem = 536881506 peak = 1220427776
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 284692, 4, 17)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 242, 369)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 805)
[M::mem_pestat] mean and std.dev: (229.96, 132.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1023)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 287, 410)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 852)
[M::mem_pestat] mean and std.dev: (309.51, 150.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1073)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 275, 395)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 813)
[M::mem_pestat] mean and std.dev: (247.93, 81.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1022)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 686066 sequences (100000206 bp) in 2.845 CPU sec, 2.900 real sec...
[M::process] read 686390 sequences (100000001 bp) in 2.080 CPU sec, 2.080 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (14, 284762, 18, 21)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (135, 177, 225)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 405)
[M::mem_pestat] mean and std.dev: (175.00, 47.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 495)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 285, 408)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 852)
[M::mem_pestat] mean and std.dev: (307.13, 149.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1074)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (73, 500, 537)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1465)
[M::mem_pestat] mean and std.dev: (409.94, 422.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2099)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 279, 325)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 681)
[M::mem_pestat] mean and std.dev: (264.67, 124.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 859)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 687028 reads in 192.408 CPU sec, 6.094 real sec
[M::mem_process_seqs] Processed 687728 reads in 132.689 CPU sec, 4.212 real sec
sorting block 129, #reads = 1075512 mem = 536878342 peak = 1220427776
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 284106, 9, 18)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (190, 304, 388)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 784)
[M::mem_pestat] mean and std.dev: (279.04, 104.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 982)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 294, 420)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 876)
[M::mem_pestat] mean and std.dev: (315.60, 153.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1104)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 228, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 662)
[M::mem_pestat] mean and std.dev: (261.76, 132.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 824)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 684708 sequences (100000044 bp) in 2.845 CPU sec, 2.913 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 283543, 2, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 209, 245)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 433)
[M::mem_pestat] mean and std.dev: (204.90, 73.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 527)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 289, 416)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 868)
[M::mem_pestat] mean and std.dev: (313.01, 153.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1094)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (214, 382, 826)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2050)
[M::mem_pestat] mean and std.dev: (626.88, 597.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3016)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 684982 sequences (100000167 bp) in 2.120 CPU sec, 2.116 real sec...
[M::mem_process_seqs] Processed 686066 reads in 181.607 CPU sec, 5.742 real sec
sorting block 130, #reads = 1075657 mem = 536879848 peak = 1220427776
[M::mem_process_seqs] Processed 686390 reads in 121.303 CPU sec, 3.839 real sec
[M::process] read 684180 sequences (100000169 bp) in 2.420 CPU sec, 2.490 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 283407, 2, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 217, 489)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1135)
[M::mem_pestat] mean and std.dev: (307.65, 263.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1458)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 303, 432)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 902)
[M::mem_pestat] mean and std.dev: (324.31, 157.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1137)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 262, 289)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 519)
[M::mem_pestat] mean and std.dev: (239.07, 81.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 634)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 683380 sequences (100000034 bp) in 1.560 CPU sec, 1.559 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 283978, 11, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 247, 432)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 936)
[M::mem_pestat] mean and std.dev: (255.65, 141.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1188)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 302, 429)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 895)
[M::mem_pestat] mean and std.dev: (322.49, 155.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1128)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (355, 867, 931)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2083)
[M::mem_pestat] mean and std.dev: (683.36, 326.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2659)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 318, 816)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2066)
[M::mem_pestat] mean and std.dev: (515.35, 379.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2691)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 283323, 6, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 231, 418)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 922)
[M::mem_pestat] mean and std.dev: (258.90, 121.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1174)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (199, 307, 437)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 913)
[M::mem_pestat] mean and std.dev: (328.06, 158.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1151)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 260, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 696)
[M::mem_pestat] mean and std.dev: (266.82, 97.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 865)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 684708 reads in 262.804 CPU sec, 8.390 real sec
sorting block 131, #reads = 1076167 mem = 536885007 peak = 1220427776
[M::mem_process_seqs] Processed 684982 reads in 203.200 CPU sec, 6.512 real sec
[M::mem_process_seqs] Processed 684180 reads in 227.564 CPU sec, 7.311 real sec
sorting block 132, #reads = 1074942 mem = 536880658 peak = 1220427776
[M::process] read 683044 sequences (100000224 bp) in 2.764 CPU sec, 2.862 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (17, 283250, 5, 21)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 268, 282)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 502)
[M::mem_pestat] mean and std.dev: (225.38, 82.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 612)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 310, 441)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 919)
[M::mem_pestat] mean and std.dev: (330.75, 159.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1158)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (161, 248, 374)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 800)
[M::mem_pestat] mean and std.dev: (238.94, 85.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1013)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682610 sequences (100000090 bp) in 2.383 CPU sec, 2.431 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 282606, 3, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 261, 324)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 642)
[M::mem_pestat] mean and std.dev: (239.19, 92.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 801)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 310, 438)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 908)
[M::mem_pestat] mean and std.dev: (330.24, 157.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1143)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (175, 257, 338)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 664)
[M::mem_pestat] mean and std.dev: (253.00, 90.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 827)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 683380 reads in 184.103 CPU sec, 5.851 real sec
sorting block 133, #reads = 1074701 mem = 536884356 peak = 1220427776
[M::mem_process_seqs] Processed 683044 reads in 127.640 CPU sec, 4.017 real sec
[M::process] read 682400 sequences (100000076 bp) in 2.445 CPU sec, 2.501 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 282873, 17, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (130, 214, 612)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1576)
[M::mem_pestat] mean and std.dev: (290.59, 261.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2058)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 313, 440)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 912)
[M::mem_pestat] mean and std.dev: (331.20, 156.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1148)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (642, 830, 1438)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3030)
[M::mem_pestat] mean and std.dev: (972.35, 496.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3826)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (229, 268, 1052)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2698)
[M::mem_pestat] mean and std.dev: (354.23, 298.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3521)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 134, #reads = 1074867 mem = 536879899 peak = 1220427776
[M::process] read 682248 sequences (100000127 bp) in 2.422 CPU sec, 2.482 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20, 282393, 3, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (145, 291, 360)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 790)
[M::mem_pestat] mean and std.dev: (237.47, 100.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1005)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 314, 442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 914)
[M::mem_pestat] mean and std.dev: (333.14, 158.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1150)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (221, 311, 347)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 599)
[M::mem_pestat] mean and std.dev: (266.29, 92.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 725)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682168 sequences (100000239 bp) in 2.000 CPU sec, 1.999 real sec...
[M::mem_process_seqs] Processed 682610 reads in 190.591 CPU sec, 6.052 real sec
[M::mem_process_seqs] Processed 682400 reads in 131.365 CPU sec, 4.170 real sec
sorting block 135, #reads = 1073445 mem = 536877897 peak = 1220427776
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 282151, 7, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 227, 340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 684)
[M::mem_pestat] mean and std.dev: (266.86, 162.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 916)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 314, 443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 919)
[M::mem_pestat] mean and std.dev: (334.02, 159.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1157)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 223, 288)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 568)
[M::mem_pestat] mean and std.dev: (206.23, 76.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 708)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 682012 sequences (100000229 bp) in 2.557 CPU sec, 2.626 real sec...
[M::process] read 681648 sequences (100000295 bp) in 2.042 CPU sec, 2.048 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 282059, 1, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (153, 233, 376)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 822)
[M::mem_pestat] mean and std.dev: (256.12, 145.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1045)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 314, 444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 920)
[M::mem_pestat] mean and std.dev: (334.69, 160.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1158)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 265, 400)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 866)
[M::mem_pestat] mean and std.dev: (270.43, 152.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1099)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682248 reads in 181.860 CPU sec, 5.760 real sec
[M::mem_process_seqs] Processed 682168 reads in 129.884 CPU sec, 4.133 real sec
sorting block 136, #reads = 1075695 mem = 536880768 peak = 1220427776
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 281571, 4, 18)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 267, 410)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 860)
[M::mem_pestat] mean and std.dev: (315.66, 186.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1085)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 316, 446)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 924)
[M::mem_pestat] mean and std.dev: (336.25, 160.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1163)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 411, 501)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1107)
[M::mem_pestat] mean and std.dev: (350.44, 154.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1410)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 681330 sequences (100000206 bp) in 2.501 CPU sec, 2.544 real sec...
[M::process] read 681236 sequences (100000038 bp) in 2.016 CPU sec, 2.022 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 281697, 4, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 219, 322)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 578)
[M::mem_pestat] mean and std.dev: (247.87, 85.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 706)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 317, 442)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 908)
[M::mem_pestat] mean and std.dev: (335.11, 157.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1141)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 225, 302)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 550)
[M::mem_pestat] mean and std.dev: (233.62, 90.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 674)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 682012 reads in 183.005 CPU sec, 5.797 real sec
sorting block 137, #reads = 1075651 mem = 536878957 peak = 1220427776
[M::mem_process_seqs] Processed 681648 reads in 123.835 CPU sec, 3.929 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 281925, 9, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 226, 307)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 591)
[M::mem_pestat] mean and std.dev: (260.35, 136.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 804)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 319, 445)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 915)
[M::mem_pestat] mean and std.dev: (337.19, 159.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1150)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 230, 411)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 873)
[M::mem_pestat] mean and std.dev: (265.50, 128.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1104)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680798 sequences (100000291 bp) in 2.488 CPU sec, 2.549 real sec...
[M::process] read 681058 sequences (100000269 bp) in 2.050 CPU sec, 2.056 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 281244, 3, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (207, 210, 301)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (19, 489)
[M::mem_pestat] mean and std.dev: (216.48, 53.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 583)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (210, 320, 446)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 918)
[M::mem_pestat] mean and std.dev: (338.37, 159.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1154)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (231, 408, 817)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1989)
[M::mem_pestat] mean and std.dev: (515.64, 343.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2575)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 681330 reads in 179.508 CPU sec, 5.688 real sec
sorting block 138, #reads = 1075896 mem = 536878221 peak = 1220427776
[M::mem_process_seqs] Processed 681236 reads in 121.978 CPU sec, 4.081 real sec
sorting block 139, #reads = 1075646 mem = 536880362 peak = 1220427776
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 281149, 3, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 225, 298)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 566)
[M::mem_pestat] mean and std.dev: (250.33, 108.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 700)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 321, 447)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 917)
[M::mem_pestat] mean and std.dev: (339.06, 159.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1152)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (163, 221, 424)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 946)
[M::mem_pestat] mean and std.dev: (268.04, 169.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1207)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 680974 sequences (100000115 bp) in 2.183 CPU sec, 2.245 real sec...
[M::process] read 680958 sequences (100000004 bp) in 1.540 CPU sec, 1.537 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23, 281973, 2, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 379, 444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 910)
[M::mem_pestat] mean and std.dev: (306.35, 118.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1143)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 322, 448)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 920)
[M::mem_pestat] mean and std.dev: (339.79, 160.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1156)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 259, 386)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 780)
[M::mem_pestat] mean and std.dev: (279.48, 118.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 977)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680798 reads in 150.067 CPU sec, 4.956 real sec
[M::mem_process_seqs] Processed 681058 reads in 91.645 CPU sec, 2.908 real sec
sorting block 140, #reads = 1076795 mem = 536880616 peak = 1220427776
[M::process] read 209434 sequences (30696997 bp) in 0.867 CPU sec, 0.892 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (22, 281603, 10, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 228, 400)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 812)
[M::mem_pestat] mean and std.dev: (293.23, 148.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1018)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 323, 451)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 929)
[M::mem_pestat] mean and std.dev: (342.15, 163.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1168)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (1114, 2058, 6340)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 16792)
[M::mem_pestat] mean and std.dev: (2706.90, 2451.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 22018)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 312, 417)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 857)
[M::mem_pestat] mean and std.dev: (294.08, 124.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1077)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 282046, 6, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (164, 238, 420)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 932)
[M::mem_pestat] mean and std.dev: (276.93, 153.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1188)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 323, 451)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 931)
[M::mem_pestat] mean and std.dev: (342.33, 163.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1171)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (222, 352, 428)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 840)
[M::mem_pestat] mean and std.dev: (321.61, 123.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1046)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (10, 86701, 1, 11)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (137, 213, 215)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 371)
[M::mem_pestat] mean and std.dev: (196.67, 70.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 477)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 311, 435)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 895)
[M::mem_pestat] mean and std.dev: (330.21, 157.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1125)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (152, 194, 356)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 764)
[M::mem_pestat] mean and std.dev: (228.09, 106.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 968)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 680974 reads in 172.301 CPU sec, 5.558 real sec
[M::mem_process_seqs] Processed 680958 reads in 131.509 CPU sec, 4.245 real sec
[M::mem_process_seqs] Processed 209434 reads in 139.028 CPU sec, 4.500 real sec
sorting block 141, #reads = 1076259 mem = 536877865 peak = 1220427776
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000c06f2
  features: 1f8bfbff fffab20b
  extended: f1bf07ab 1a407f7e
  amd bits: 2c100800 00000121
     brand: Intel(R) Xeon(R) Platinum 8559C
threads: 31
algo: bwa-mem
license: sentieon:klib=31
reads: 153067436
overall: 69999554560 mem 23346.623 user 221.639 sys 774.336 real
[main] Version: 0.7.17-r1188
[main] CMD: /opt/conda/share/sentieon-202308.03-3/libexec/bwa mem -K 100000000 -Y -R @RG\tID:A23MHWWLT4.1136_5Q-T1-TDNA-1_A23MHWWLT4_1.L002\tPU:L002\tSM:1136_5Q-T1-TDNA-1_A23MHWWLT4_1\tLB:1136_5Q-T1-TDNA-1_A23MHWWLT4_1\tDS:s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta\tPL:ILLUMINA -t 31 ./BWAIndex/Homo_sapiens_assembly38.fasta.64 1136_5Q-T1-TDNA-1_A23MHWWLT4_1_R1.fastq.gz 1136_5Q-T1-TDNA-1_A23MHWWLT4_1_R2.fastq.gz
[main] Real time: 774.373 sec; CPU: 23568.271 sec
sorting block 142, #reads = 913426 mem = 456453038 peak = 1227767808
uniq header count 1
merging 143 blocks
sw version: sentieon-genomics-202308.03
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000c06f2
  features: 1f8bfbff fffab20b
  extended: f1bf07ab 1a407f7e
  amd bits: 2c100800 00000121
     brand: Intel(R) Xeon(R) Platinum 8559C
threads: 31 max 72
algo: util-sort
license: sentieon:util=1
output file size: 8242504590
output reads: 153972105
bam_mem_sort: 143 calls 83.895 user 0.318 sys 87.989 real
bam_write: 143 calls 96.102 user 4.586 sys 181.640 real
execute: 1 calls 42.311 user 0.864 sys 838.043 real
merge_files: 1 calls 42.289 user 0.833 sys 63.172 real
parse_chunk: 2286 calls 136.663 user 28.685 sys 199.124 real
read_chunk: 6165 calls 59.802 user 36.910 sys 747.625 real
sort_block: 1 calls 38.340 user 36.357 sys 720.536 real
write_chunk: 3877 calls 41.958 user 0.537 sys 62.288 real
overall: 3344166912 mem 2489.157 user 82.793 sys 838.059 real
ls: cannot access '*.cram': No such file or directory