This software is licensed to bgold@natera.com by Sentieon Inc.
cmdline: /opt/conda/share/sentieon-202308.03-3/libexec/util sort -r Homo_sapiens_assembly38.fasta -t 31 -o 1136_8DV-T1-TDNA-1_A23MHWWLT4_1.bam --sam2bam -
This software is licensed to bgold@natera.com by Sentieon Inc.
version: sentieon-genomics-202308.03
[M::bwa_idx_load_from_disk] read 3171 ALT contigs
[M::main_mem] bwa index loaded in 2254.746 CPU sec, 90.982 real sec
[M::process] read 724642 sequences (100000044 bp) in 1.355 CPU sec, 1.359 real sec...
[M::process] read 724226 sequences (100000062 bp) in 2.086 CPU sec, 2.109 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 291810, 22, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 311, 779)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2011)
[M::mem_pestat] mean and std.dev: (445.91, 470.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2627)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 188, 285)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 591)
[M::mem_pestat] mean and std.dev: (216.69, 112.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 744)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (728, 1057, 1688)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3608)
[M::mem_pestat] mean and std.dev: (1070.55, 677.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4568)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (176, 189, 381)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 791)
[M::mem_pestat] mean and std.dev: (253.81, 154.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 996)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724024 sequences (100000200 bp) in 2.181 CPU sec, 2.626 real sec...
[M::process] read 722866 sequences (100000000 bp) in 2.044 CPU sec, 2.849 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 292112, 21, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (141, 282, 976)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2646)
[M::mem_pestat] mean and std.dev: (519.38, 683.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3481)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 190, 288)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 598)
[M::mem_pestat] mean and std.dev: (218.71, 113.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 753)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (89, 325, 1294)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3704)
[M::mem_pestat] mean and std.dev: (871.38, 1110.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5314)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 263, 687)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1721)
[M::mem_pestat] mean and std.dev: (370.62, 272.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2238)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 724642 reads in 269.438 CPU sec, 9.850 real sec
[M::mem_process_seqs] Processed 724226 reads in 168.431 CPU sec, 6.305 real sec
sorting block 0, #reads = 1094711 mem = 536878042 peak = 574099456
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 291765, 30, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (213, 446, 1469)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3981)
[M::mem_pestat] mean and std.dev: (869.52, 899.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5237)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 190, 288)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 598)
[M::mem_pestat] mean and std.dev: (219.04, 114.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 753)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (103, 436, 1392)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3970)
[M::mem_pestat] mean and std.dev: (420.28, 446.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5259)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (252, 392, 841)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2019)
[M::mem_pestat] mean and std.dev: (439.00, 288.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2608)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 721562 sequences (100000135 bp) in 2.754 CPU sec, 2.918 real sec...
[M::process] read 721356 sequences (100000148 bp) in 2.276 CPU sec, 2.320 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 291151, 20, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (233, 330, 1037)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2645)
[M::mem_pestat] mean and std.dev: (582.68, 638.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3449)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 192, 291)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 605)
[M::mem_pestat] mean and std.dev: (221.07, 115.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 762)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (678, 785, 1438)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2958)
[M::mem_pestat] mean and std.dev: (724.00, 480.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3718)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 265, 1128)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3052)
[M::mem_pestat] mean and std.dev: (554.85, 694.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4014)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 724024 reads in 256.764 CPU sec, 8.420 real sec
[M::mem_process_seqs] Processed 722866 reads in 175.895 CPU sec, 5.791 real sec
sorting block 1, #reads = 1093142 mem = 536885623 peak = 734220288
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 290945, 13, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (142, 234, 765)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2011)
[M::mem_pestat] mean and std.dev: (341.73, 386.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2634)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 194, 296)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 618)
[M::mem_pestat] mean and std.dev: (224.21, 118.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 779)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 782, 3414)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9948)
[M::mem_pestat] mean and std.dev: (1239.08, 1523.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13215)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (197, 394, 599)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1403)
[M::mem_pestat] mean and std.dev: (429.03, 303.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1805)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720382 sequences (100000175 bp) in 3.224 CPU sec, 3.506 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 291024, 31, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (255, 430, 753)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1749)
[M::mem_pestat] mean and std.dev: (468.62, 404.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2247)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 195, 298)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 624)
[M::mem_pestat] mean and std.dev: (225.74, 119.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 787)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (311, 654, 929)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2165)
[M::mem_pestat] mean and std.dev: (604.26, 423.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2783)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 262, 644)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1604)
[M::mem_pestat] mean and std.dev: (415.37, 339.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2084)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720440 sequences (100000103 bp) in 2.279 CPU sec, 2.326 real sec...
[M::mem_process_seqs] Processed 721562 reads in 258.854 CPU sec, 8.475 real sec
[M::mem_process_seqs] Processed 721356 reads in 174.830 CPU sec, 5.753 real sec
sorting block 2, #reads = 1092848 mem = 536878160 peak = 734220288
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 290660, 26, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 452, 1462)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4000)
[M::mem_pestat] mean and std.dev: (576.26, 560.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5269)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 196, 300)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 628)
[M::mem_pestat] mean and std.dev: (227.02, 120.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 792)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (133, 273, 1778)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5068)
[M::mem_pestat] mean and std.dev: (614.46, 658.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6713)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (292, 556, 2531)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7009)
[M::mem_pestat] mean and std.dev: (1221.65, 1184.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9248)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720146 sequences (100000132 bp) in 3.522 CPU sec, 3.849 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (21, 290465, 21, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 313, 1836)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5066)
[M::mem_pestat] mean and std.dev: (903.10, 860.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6681)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 196, 300)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 630)
[M::mem_pestat] mean and std.dev: (227.08, 120.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 795)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (275, 518, 1293)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3329)
[M::mem_pestat] mean and std.dev: (765.90, 718.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4347)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (257, 394, 750)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1736)
[M::mem_pestat] mean and std.dev: (440.34, 290.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2229)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 720382 reads in 263.683 CPU sec, 8.738 real sec
sorting block 3, #reads = 1091001 mem = 536877268 peak = 745508864
[M::process] read 719486 sequences (100000212 bp) in 2.949 CPU sec, 3.059 real sec...
[M::mem_process_seqs] Processed 720440 reads in 181.155 CPU sec, 6.048 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23, 290040, 24, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 237, 477)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1081)
[M::mem_pestat] mean and std.dev: (287.75, 219.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1383)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 196, 299)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 625)
[M::mem_pestat] mean and std.dev: (226.77, 120.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 788)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (435, 1142, 2737)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7341)
[M::mem_pestat] mean and std.dev: (1779.54, 1835.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9643)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (281, 445, 831)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1931)
[M::mem_pestat] mean and std.dev: (512.97, 410.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2481)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 4, #reads = 1090557 mem = 536889753 peak = 810524672
[M::process] read 719310 sequences (100000191 bp) in 3.111 CPU sec, 3.413 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (21, 290025, 17, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 224, 364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 798)
[M::mem_pestat] mean and std.dev: (270.71, 131.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1015)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 197, 299)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 625)
[M::mem_pestat] mean and std.dev: (227.08, 119.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 788)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (108, 364, 1605)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4599)
[M::mem_pestat] mean and std.dev: (709.65, 767.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6096)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 573, 1228)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3330)
[M::mem_pestat] mean and std.dev: (722.75, 713.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4381)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 720146 reads in 230.219 CPU sec, 7.878 real sec
[M::mem_process_seqs] Processed 719486 reads in 162.933 CPU sec, 5.639 real sec
[M::process] read 719698 sequences (100000166 bp) in 3.045 CPU sec, 3.497 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 290249, 23, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 283, 586)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1454)
[M::mem_pestat] mean and std.dev: (363.14, 321.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1888)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 196, 301)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 631)
[M::mem_pestat] mean and std.dev: (227.38, 119.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 796)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (294, 361, 831)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1905)
[M::mem_pestat] mean and std.dev: (524.67, 457.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2442)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 241, 384)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 838)
[M::mem_pestat] mean and std.dev: (287.47, 172.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1065)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 5, #reads = 1091046 mem = 536878957 peak = 810524672
[M::mem_process_seqs] Processed 719310 reads in 132.836 CPU sec, 4.610 real sec
[M::process] read 719238 sequences (100000030 bp) in 3.421 CPU sec, 3.714 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 289992, 16, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (125, 225, 580)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1490)
[M::mem_pestat] mean and std.dev: (294.05, 218.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1945)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 195, 297)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 619)
[M::mem_pestat] mean and std.dev: (225.52, 118.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 780)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (688, 857, 2553)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6283)
[M::mem_pestat] mean and std.dev: (1415.81, 1232.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8148)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 828, 1760)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4792)
[M::mem_pestat] mean and std.dev: (785.89, 703.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6308)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 719698 reads in 134.200 CPU sec, 4.611 real sec
sorting block 6, #reads = 1090476 mem = 536879794 peak = 810524672
[M::process] read 719300 sequences (100000158 bp) in 3.362 CPU sec, 3.698 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 290087, 17, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (369, 443, 688)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1326)
[M::mem_pestat] mean and std.dev: (470.94, 226.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1645)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 196, 299)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 623)
[M::mem_pestat] mean and std.dev: (226.74, 119.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 785)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (319, 612, 1596)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4150)
[M::mem_pestat] mean and std.dev: (686.87, 563.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5427)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 378, 1528)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4160)
[M::mem_pestat] mean and std.dev: (823.13, 1006.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5476)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 719238 reads in 132.528 CPU sec, 4.655 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 290154, 15, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (208, 337, 756)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1852)
[M::mem_pestat] mean and std.dev: (458.00, 426.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2400)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 197, 300)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 628)
[M::mem_pestat] mean and std.dev: (227.47, 119.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 792)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (626, 716, 1439)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3065)
[M::mem_pestat] mean and std.dev: (845.85, 618.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3878)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (339, 470, 839)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1839)
[M::mem_pestat] mean and std.dev: (587.70, 399.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2339)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 718430 sequences (100000113 bp) in 3.297 CPU sec, 3.744 real sec...
[M::mem_process_seqs] Processed 719300 reads in 133.635 CPU sec, 4.653 real sec
sorting block 7, #reads = 1090075 mem = 536878603 peak = 810524672
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 289667, 16, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 317, 1137)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3101)
[M::mem_pestat] mean and std.dev: (668.23, 677.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4083)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 198, 302)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 632)
[M::mem_pestat] mean and std.dev: (229.06, 120.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 797)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (455, 777, 1384)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3242)
[M::mem_pestat] mean and std.dev: (794.50, 745.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4171)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 351, 701)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1699)
[M::mem_pestat] mean and std.dev: (511.81, 403.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2198)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 717356 sequences (100000007 bp) in 3.154 CPU sec, 3.729 real sec...
[M::mem_process_seqs] Processed 718430 reads in 129.648 CPU sec, 4.596 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 289862, 19, 22)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 298, 853)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2199)
[M::mem_pestat] mean and std.dev: (482.97, 441.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2872)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 200, 305)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 639)
[M::mem_pestat] mean and std.dev: (230.88, 121.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 806)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (247, 864, 901)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2209)
[M::mem_pestat] mean and std.dev: (766.94, 557.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2998)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 463, 1013)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2745)
[M::mem_pestat] mean and std.dev: (640.45, 663.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3611)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 8, #reads = 1090092 mem = 536880512 peak = 810524672
[M::process] read 717612 sequences (100000126 bp) in 3.304 CPU sec, 3.624 real sec...
[M::mem_process_seqs] Processed 717356 reads in 130.589 CPU sec, 4.555 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 289289, 17, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 232, 660)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1644)
[M::mem_pestat] mean and std.dev: (352.09, 330.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2136)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::process] read 716610 sequences (100000007 bp) in 3.220 CPU sec, 3.572 real sec...
[M::mem_pestat] (25, 50, 75) percentile: (138, 200, 304)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 636)
[M::mem_pestat] mean and std.dev: (230.46, 121.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 802)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (553, 755, 1396)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3082)
[M::mem_pestat] mean and std.dev: (668.50, 382.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3925)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 493, 2086)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5812)
[M::mem_pestat] mean and std.dev: (861.38, 837.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7675)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 717612 reads in 133.358 CPU sec, 4.759 real sec
sorting block 9, #reads = 1091772 mem = 536877835 peak = 810524672
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 289221, 15, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (294, 395, 1102)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2718)
[M::mem_pestat] mean and std.dev: (602.90, 534.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3526)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (139, 202, 308)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 646)
[M::mem_pestat] mean and std.dev: (233.05, 123.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 815)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (526, 781, 2142)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5374)
[M::mem_pestat] mean and std.dev: (1097.33, 785.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6990)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (170, 238, 358)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 734)
[M::mem_pestat] mean and std.dev: (211.62, 70.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 922)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 716774 sequences (100000047 bp) in 3.161 CPU sec, 3.457 real sec...
[M::mem_process_seqs] Processed 716610 reads in 129.560 CPU sec, 4.558 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 289970, 13, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (184, 355, 758)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1906)
[M::mem_pestat] mean and std.dev: (446.40, 368.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2480)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (139, 203, 311)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 655)
[M::mem_pestat] mean and std.dev: (234.58, 125.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 827)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (32, 528, 1773)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5255)
[M::mem_pestat] mean and std.dev: (1028.23, 1262.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6996)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (245, 417, 534)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1112)
[M::mem_pestat] mean and std.dev: (367.08, 227.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1401)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 10, #reads = 1089041 mem = 536876156 peak = 810524672
[M::process] read 716392 sequences (100000279 bp) in 3.283 CPU sec, 3.592 real sec...
[M::mem_process_seqs] Processed 716774 reads in 126.660 CPU sec, 4.476 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 289085, 21, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 290, 629)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1587)
[M::mem_pestat] mean and std.dev: (363.22, 273.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2066)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (139, 203, 311)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 655)
[M::mem_pestat] mean and std.dev: (235.01, 125.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 827)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (433, 2230, 2505)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6649)
[M::mem_pestat] mean and std.dev: (1990.33, 1868.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9463)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 289, 748)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1832)
[M::mem_pestat] mean and std.dev: (418.64, 425.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2374)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723158 sequences (100000050 bp) in 3.403 CPU sec, 3.822 real sec...
[M::mem_process_seqs] Processed 716392 reads in 127.928 CPU sec, 4.451 real sec
sorting block 11, #reads = 1089176 mem = 536879248 peak = 810524672
[M::process] read 724660 sequences (100000060 bp) in 3.104 CPU sec, 3.423 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 291313, 20, 18)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (129, 234, 1180)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3282)
[M::mem_pestat] mean and std.dev: (555.36, 694.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4333)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 192, 294)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 616)
[M::mem_pestat] mean and std.dev: (222.39, 117.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 777)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (327, 1550, 2835)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7851)
[M::mem_pestat] mean and std.dev: (1611.20, 1215.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10359)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 297, 392)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 806)
[M::mem_pestat] mean and std.dev: (283.94, 148.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1013)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 723158 reads in 131.702 CPU sec, 4.706 real sec
sorting block 12, #reads = 1089560 mem = 536875743 peak = 810524672
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 291811, 17, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 492, 3443)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9925)
[M::mem_pestat] mean and std.dev: (1462.18, 1698.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13166)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 189, 289)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 603)
[M::mem_pestat] mean and std.dev: (219.34, 115.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 760)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (234, 531, 1594)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4314)
[M::mem_pestat] mean and std.dev: (850.00, 996.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5674)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (233, 337, 1042)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2660)
[M::mem_pestat] mean and std.dev: (607.47, 654.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3469)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724110 sequences (100000089 bp) in 3.650 CPU sec, 4.068 real sec...
[M::mem_process_seqs] Processed 724660 reads in 125.363 CPU sec, 4.344 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 291944, 13, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 203, 666)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1662)
[M::mem_pestat] mean and std.dev: (294.22, 209.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2160)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 190, 290)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 604)
[M::mem_pestat] mean and std.dev: (219.84, 115.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 761)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (452, 564, 1229)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2783)
[M::mem_pestat] mean and std.dev: (712.50, 367.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3560)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (169, 281, 697)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1753)
[M::mem_pestat] mean and std.dev: (399.62, 300.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2281)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723756 sequences (100000149 bp) in 3.180 CPU sec, 3.528 real sec...
[M::mem_process_seqs] Processed 724110 reads in 125.799 CPU sec, 4.409 real sec
sorting block 13, #reads = 1091092 mem = 536878980 peak = 810524672
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 291625, 21, 51)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 265, 679)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1737)
[M::mem_pestat] mean and std.dev: (337.23, 288.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2266)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 191, 293)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 613)
[M::mem_pestat] mean and std.dev: (222.06, 117.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 773)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (307, 564, 1803)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4795)
[M::mem_pestat] mean and std.dev: (869.20, 721.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6291)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (255, 378, 1446)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3828)
[M::mem_pestat] mean and std.dev: (689.94, 641.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5019)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722776 sequences (100000010 bp) in 3.209 CPU sec, 3.651 real sec...
[M::mem_process_seqs] Processed 723756 reads in 127.673 CPU sec, 4.507 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 291572, 17, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 443, 1243)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3363)
[M::mem_pestat] mean and std.dev: (658.17, 627.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4423)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 192, 296)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 620)
[M::mem_pestat] mean and std.dev: (223.88, 119.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 782)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (298, 298, 1561)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4087)
[M::mem_pestat] mean and std.dev: (798.24, 725.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5350)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (224, 397, 1364)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3644)
[M::mem_pestat] mean and std.dev: (733.71, 590.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4784)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 14, #reads = 1094842 mem = 536887138 peak = 810524672
[M::process] read 721830 sequences (100000023 bp) in 3.673 CPU sec, 4.029 real sec...
[M::mem_process_seqs] Processed 722776 reads in 128.084 CPU sec, 4.432 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 290965, 28, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (185, 302, 1260)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3410)
[M::mem_pestat] mean and std.dev: (723.61, 756.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4485)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 194, 298)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 624)
[M::mem_pestat] mean and std.dev: (225.35, 119.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 787)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (61, 550, 1133)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3277)
[M::mem_pestat] mean and std.dev: (516.36, 499.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4349)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (255, 278, 540)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1110)
[M::mem_pestat] mean and std.dev: (362.48, 198.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1395)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 721322 sequences (100000123 bp) in 3.375 CPU sec, 3.777 real sec...
[M::mem_process_seqs] Processed 721830 reads in 125.027 CPU sec, 4.250 real sec
sorting block 15, #reads = 1094467 mem = 536878298 peak = 814272512
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 290716, 17, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 346, 1406)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3810)
[M::mem_pestat] mean and std.dev: (832.20, 876.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5012)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 194, 300)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 630)
[M::mem_pestat] mean and std.dev: (226.63, 121.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 795)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (621, 1008, 2006)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4776)
[M::mem_pestat] mean and std.dev: (1232.06, 872.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6161)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 287, 1087)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2993)
[M::mem_pestat] mean and std.dev: (462.62, 512.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3946)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 721124 sequences (100000130 bp) in 3.138 CPU sec, 3.409 real sec...
[M::mem_process_seqs] Processed 721322 reads in 122.168 CPU sec, 4.093 real sec
sorting block 16, #reads = 1093207 mem = 536880056 peak = 837787648
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 290876, 16, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (155, 579, 846)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2228)
[M::mem_pestat] mean and std.dev: (582.45, 484.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2919)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 195, 300)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 630)
[M::mem_pestat] mean and std.dev: (226.87, 121.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 795)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (57, 121, 963)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2775)
[M::mem_pestat] mean and std.dev: (431.93, 525.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3681)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (182, 277, 999)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2633)
[M::mem_pestat] mean and std.dev: (591.57, 534.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3450)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720948 sequences (100000220 bp) in 3.625 CPU sec, 3.940 real sec...
[M::mem_process_seqs] Processed 721124 reads in 121.286 CPU sec, 4.064 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (18, 290821, 17, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 273, 586)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1454)
[M::mem_pestat] mean and std.dev: (357.24, 243.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1888)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 195, 299)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 627)
[M::mem_pestat] mean and std.dev: (226.26, 120.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 791)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 431, 1298)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3472)
[M::mem_pestat] mean and std.dev: (660.06, 649.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4559)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (262, 417, 941)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2299)
[M::mem_pestat] mean and std.dev: (591.19, 518.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2978)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720706 sequences (100000062 bp) in 3.404 CPU sec, 3.603 real sec...
[M::mem_process_seqs] Processed 720948 reads in 118.542 CPU sec, 3.976 real sec
sorting block 17, #reads = 1094022 mem = 536878476 peak = 837787648
[M::process] read 719936 sequences (100000021 bp) in 3.056 CPU sec, 3.206 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 290291, 13, 47)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 359, 1276)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3422)
[M::mem_pestat] mean and std.dev: (867.62, 955.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4688)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 195, 299)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 627)
[M::mem_pestat] mean and std.dev: (226.62, 120.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 791)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 1429, 2009)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5661)
[M::mem_pestat] mean and std.dev: (1207.85, 1103.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7487)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 421, 773)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1985)
[M::mem_pestat] mean and std.dev: (403.79, 275.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2591)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 18, #reads = 1093213 mem = 536876767 peak = 837787648
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 290741, 17, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 274, 632)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1550)
[M::mem_pestat] mean and std.dev: (343.47, 279.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2009)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 196, 300)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 628)
[M::mem_pestat] mean and std.dev: (226.97, 120.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 792)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (545, 758, 2261)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5693)
[M::mem_pestat] mean and std.dev: (1275.12, 1303.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7409)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 356, 663)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1587)
[M::mem_pestat] mean and std.dev: (402.59, 328.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2049)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720344 sequences (100000067 bp) in 2.874 CPU sec, 3.055 real sec...
[M::mem_process_seqs] Processed 720706 reads in 208.278 CPU sec, 6.847 real sec
[M::mem_process_seqs] Processed 719936 reads in 146.223 CPU sec, 4.746 real sec
[M::process] read 719976 sequences (100000110 bp) in 3.208 CPU sec, 3.378 real sec...
sorting block 19, #reads = 1090851 mem = 536882629 peak = 837787648
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 291078, 15, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 236, 932)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2386)
[M::mem_pestat] mean and std.dev: (345.52, 269.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3113)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 195, 297)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 619)
[M::mem_pestat] mean and std.dev: (225.11, 118.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 780)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (288, 1134, 1825)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4899)
[M::mem_pestat] mean and std.dev: (1072.40, 764.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6436)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (195, 317, 1743)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4839)
[M::mem_pestat] mean and std.dev: (748.51, 769.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6387)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 719464 sequences (100000018 bp) in 2.970 CPU sec, 3.126 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 289719, 15, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 467, 639)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1509)
[M::mem_pestat] mean and std.dev: (413.48, 243.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1944)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 195, 297)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 619)
[M::mem_pestat] mean and std.dev: (225.26, 118.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 780)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 679, 747)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1809)
[M::mem_pestat] mean and std.dev: (592.71, 545.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2775)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 307, 486)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1086)
[M::mem_pestat] mean and std.dev: (314.47, 222.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1386)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 720344 reads in 202.544 CPU sec, 6.444 real sec
[M::process] read 719100 sequences (100000280 bp) in 2.296 CPU sec, 2.348 real sec...
[M::mem_process_seqs] Processed 719976 reads in 143.539 CPU sec, 4.543 real sec
sorting block 20, #reads = 1091810 mem = 536880686 peak = 837787648
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 290292, 27, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (240, 378, 1476)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3948)
[M::mem_pestat] mean and std.dev: (724.49, 783.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5184)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 197, 298)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 622)
[M::mem_pestat] mean and std.dev: (226.25, 118.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 784)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (103, 144, 927)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2575)
[M::mem_pestat] mean and std.dev: (427.12, 413.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3399)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 249, 393)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 845)
[M::mem_pestat] mean and std.dev: (229.70, 81.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1071)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 719104 sequences (100000186 bp) in 2.825 CPU sec, 2.954 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 289812, 16, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (232, 512, 1165)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3031)
[M::mem_pestat] mean and std.dev: (689.62, 669.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3964)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 198, 300)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 626)
[M::mem_pestat] mean and std.dev: (228.03, 120.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 789)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (16, 534, 1313)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3907)
[M::mem_pestat] mean and std.dev: (368.69, 452.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5204)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 319, 609)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1415)
[M::mem_pestat] mean and std.dev: (385.97, 257.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1818)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 718620 sequences (100000189 bp) in 2.289 CPU sec, 2.297 real sec...
[M::mem_process_seqs] Processed 719464 reads in 198.638 CPU sec, 6.317 real sec
sorting block 21, #reads = 1090492 mem = 536880480 peak = 876769280
[M::mem_process_seqs] Processed 719100 reads in 136.626 CPU sec, 4.337 real sec
sorting block 22, #reads = 1090611 mem = 536879907 peak = 937869312
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 290256, 20, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (183, 244, 850)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2184)
[M::mem_pestat] mean and std.dev: (402.53, 454.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2851)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 197, 301)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 629)
[M::mem_pestat] mean and std.dev: (227.75, 119.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 793)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (168, 573, 1591)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4437)
[M::mem_pestat] mean and std.dev: (860.21, 1018.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5860)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 488, 973)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2493)
[M::mem_pestat] mean and std.dev: (522.79, 483.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3253)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 718052 sequences (100000133 bp) in 3.102 CPU sec, 3.206 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 290134, 26, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 222, 487)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1077)
[M::mem_pestat] mean and std.dev: (218.40, 104.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1372)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 199, 304)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 638)
[M::mem_pestat] mean and std.dev: (230.07, 122.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 805)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (585, 800, 1534)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3432)
[M::mem_pestat] mean and std.dev: (913.95, 582.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4381)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 352, 995)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2563)
[M::mem_pestat] mean and std.dev: (550.42, 580.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3347)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 717950 sequences (100000209 bp) in 1.857 CPU sec, 1.861 real sec...
[M::mem_process_seqs] Processed 719104 reads in 191.017 CPU sec, 6.091 real sec
[M::mem_process_seqs] Processed 718620 reads in 132.971 CPU sec, 4.220 real sec
sorting block 23, #reads = 1090667 mem = 536878336 peak = 937869312
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 290124, 23, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (133, 215, 664)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1726)
[M::mem_pestat] mean and std.dev: (359.11, 405.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2257)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 199, 305)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 641)
[M::mem_pestat] mean and std.dev: (230.51, 122.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 809)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (326, 617, 1522)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3914)
[M::mem_pestat] mean and std.dev: (748.26, 723.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5110)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (185, 308, 476)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1058)
[M::mem_pestat] mean and std.dev: (329.79, 172.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1349)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 718254 sequences (100000191 bp) in 2.488 CPU sec, 2.574 real sec...
[M::process] read 721702 sequences (100000169 bp) in 1.800 CPU sec, 1.802 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (17, 289830, 29, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (370, 595, 1506)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3778)
[M::mem_pestat] mean and std.dev: (828.56, 760.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4914)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (138, 200, 306)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 642)
[M::mem_pestat] mean and std.dev: (231.27, 122.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 810)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (244, 788, 3435)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9817)
[M::mem_pestat] mean and std.dev: (1874.07, 2308.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 13008)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (154, 204, 373)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 811)
[M::mem_pestat] mean and std.dev: (206.48, 83.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1030)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 718052 reads in 187.042 CPU sec, 5.940 real sec
sorting block 24, #reads = 1090033 mem = 536877604 peak = 937869312
[M::mem_process_seqs] Processed 717950 reads in 129.830 CPU sec, 4.140 real sec
[M::process] read 726522 sequences (100000202 bp) in 3.290 CPU sec, 3.448 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 291170, 28, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 311, 1180)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3176)
[M::mem_pestat] mean and std.dev: (644.76, 838.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4174)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 194, 297)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 621)
[M::mem_pestat] mean and std.dev: (224.82, 119.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 783)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 464, 1435)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3933)
[M::mem_pestat] mean and std.dev: (593.12, 565.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5182)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 328, 706)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1700)
[M::mem_pestat] mean and std.dev: (469.46, 402.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2197)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726476 sequences (100000016 bp) in 1.800 CPU sec, 1.805 real sec...
[M::mem_process_seqs] Processed 721702 reads in 109.423 CPU sec, 3.466 real sec
sorting block 25, #reads = 1089086 mem = 536878883 peak = 937869312
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 289906, 18, 19)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (202, 323, 564)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1288)
[M::mem_pestat] mean and std.dev: (423.39, 333.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1758)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 199, 306)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 644)
[M::mem_pestat] mean and std.dev: (231.30, 123.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 813)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (83, 629, 1064)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3026)
[M::mem_pestat] mean and std.dev: (695.44, 669.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4007)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 319, 1089)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2919)
[M::mem_pestat] mean and std.dev: (564.41, 576.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3834)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 292775, 16, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 278, 666)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1554)
[M::mem_pestat] mean and std.dev: (396.59, 273.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1998)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 186, 283)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 587)
[M::mem_pestat] mean and std.dev: (215.22, 112.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 739)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (94, 1169, 2148)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6256)
[M::mem_pestat] mean and std.dev: (1105.44, 1141.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8310)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (211, 382, 3944)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 11410)
[M::mem_pestat] mean and std.dev: (1515.42, 1991.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 15143)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 718254 reads in 287.173 CPU sec, 9.115 real sec
[M::process] read 724826 sequences (100000019 bp) in 2.267 CPU sec, 2.289 real sec...
[M::mem_process_seqs] Processed 726522 reads in 152.056 CPU sec, 4.852 real sec
sorting block 26, #reads = 1090661 mem = 536878145 peak = 937869312
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 292881, 19, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (284, 451, 827)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1913)
[M::mem_pestat] mean and std.dev: (522.88, 377.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2456)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 187, 285)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 593)
[M::mem_pestat] mean and std.dev: (216.31, 113.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 747)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (691, 1366, 1998)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4612)
[M::mem_pestat] mean and std.dev: (1207.35, 868.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5919)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (260, 486, 1408)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3704)
[M::mem_pestat] mean and std.dev: (850.75, 795.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4852)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723886 sequences (100000190 bp) in 2.615 CPU sec, 2.718 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 291648, 11, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 312, 1437)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3921)
[M::mem_pestat] mean and std.dev: (583.79, 705.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5163)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 189, 288)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 600)
[M::mem_pestat] mean and std.dev: (218.77, 114.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 756)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (417, 424, 1221)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2829)
[M::mem_pestat] mean and std.dev: (486.70, 449.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3633)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (276, 302, 515)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 993)
[M::mem_pestat] mean and std.dev: (314.19, 131.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1232)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722528 sequences (100000187 bp) in 1.950 CPU sec, 1.949 real sec...
[M::mem_process_seqs] Processed 726476 reads in 180.109 CPU sec, 5.719 real sec
sorting block 27, #reads = 1094615 mem = 536877380 peak = 937869312
[M::mem_process_seqs] Processed 724826 reads in 123.870 CPU sec, 3.939 real sec
sorting block 28, #reads = 1095942 mem = 536878590 peak = 937869312
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 292098, 9, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (147, 274, 404)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 918)
[M::mem_pestat] mean and std.dev: (282.21, 194.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1175)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 191, 292)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 610)
[M::mem_pestat] mean and std.dev: (221.46, 116.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 769)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 367, 597)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1367)
[M::mem_pestat] mean and std.dev: (351.93, 155.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1752)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 722008 sequences (100000124 bp) in 3.135 CPU sec, 3.259 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 291523, 12, 21)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (169, 319, 766)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1960)
[M::mem_pestat] mean and std.dev: (386.59, 323.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2557)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 193, 295)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 617)
[M::mem_pestat] mean and std.dev: (223.75, 118.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 778)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (87, 546, 4083)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12075)
[M::mem_pestat] mean and std.dev: (1628.58, 2313.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 16071)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (146, 205, 539)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1325)
[M::mem_pestat] mean and std.dev: (312.80, 278.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1718)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 721334 sequences (100000060 bp) in 1.790 CPU sec, 1.787 real sec...
[M::mem_process_seqs] Processed 723886 reads in 177.641 CPU sec, 5.638 real sec
[M::mem_process_seqs] Processed 722528 reads in 123.209 CPU sec, 3.905 real sec
sorting block 29, #reads = 1094955 mem = 536882084 peak = 937869312
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 291368, 18, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 459, 1300)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3438)
[M::mem_pestat] mean and std.dev: (419.16, 305.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4507)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 194, 297)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 623)
[M::mem_pestat] mean and std.dev: (224.87, 118.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 786)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (10, 59, 1446)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4318)
[M::mem_pestat] mean and std.dev: (681.67, 1167.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5754)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 272, 513)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1143)
[M::mem_pestat] mean and std.dev: (296.00, 166.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1458)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 721080 sequences (100000244 bp) in 2.377 CPU sec, 2.456 real sec...
[M::process] read 720420 sequences (100000233 bp) in 1.749 CPU sec, 1.750 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (14, 290856, 13, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 445, 920)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2418)
[M::mem_pestat] mean and std.dev: (497.50, 379.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3167)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 195, 299)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 627)
[M::mem_pestat] mean and std.dev: (226.58, 120.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 791)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (239, 969, 7824)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 22994)
[M::mem_pestat] mean and std.dev: (2440.85, 3219.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 30579)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (234, 812, 1539)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4149)
[M::mem_pestat] mean and std.dev: (783.48, 584.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5454)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 722008 reads in 177.302 CPU sec, 5.639 real sec
sorting block 30, #reads = 1093266 mem = 536877811 peak = 937869312
[M::mem_process_seqs] Processed 721334 reads in 121.820 CPU sec, 3.881 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 290596, 21, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 439, 522)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1244)
[M::mem_pestat] mean and std.dev: (373.77, 254.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1605)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 196, 300)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 630)
[M::mem_pestat] mean and std.dev: (226.92, 120.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 795)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (395, 995, 1846)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4748)
[M::mem_pestat] mean and std.dev: (1256.29, 987.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6199)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (238, 375, 750)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1774)
[M::mem_pestat] mean and std.dev: (415.43, 251.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2286)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720676 sequences (100000010 bp) in 2.957 CPU sec, 3.049 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 289921, 13, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 306, 447)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1007)
[M::mem_pestat] mean and std.dev: (291.44, 171.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1287)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 196, 301)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 631)
[M::mem_pestat] mean and std.dev: (227.46, 120.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 796)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 319, 4375)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12727)
[M::mem_pestat] mean and std.dev: (2263.54, 2566.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 16903)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (251, 405, 795)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1883)
[M::mem_pestat] mean and std.dev: (487.44, 374.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2427)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 719866 sequences (100000282 bp) in 2.010 CPU sec, 2.004 real sec...
[M::mem_process_seqs] Processed 721080 reads in 172.012 CPU sec, 5.439 real sec
sorting block 31, #reads = 1092772 mem = 536878878 peak = 937869312
[M::mem_process_seqs] Processed 720420 reads in 117.817 CPU sec, 3.731 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 290727, 16, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 289, 555)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1277)
[M::mem_pestat] mean and std.dev: (305.21, 180.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1638)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 195, 298)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 624)
[M::mem_pestat] mean and std.dev: (225.84, 119.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 787)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (224, 528, 969)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2459)
[M::mem_pestat] mean and std.dev: (559.33, 370.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3204)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (153, 420, 1502)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4200)
[M::mem_pestat] mean and std.dev: (633.31, 550.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5549)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 32, #reads = 1092468 mem = 536878646 peak = 937869312
[M::process] read 719682 sequences (100000006 bp) in 3.165 CPU sec, 3.338 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 290793, 11, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 278, 633)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1597)
[M::mem_pestat] mean and std.dev: (340.68, 284.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2079)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 196, 298)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 622)
[M::mem_pestat] mean and std.dev: (226.28, 119.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 784)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (288, 594, 908)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2148)
[M::mem_pestat] mean and std.dev: (533.80, 356.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2768)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (223, 279, 426)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 832)
[M::mem_pestat] mean and std.dev: (263.15, 82.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1035)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 720676 reads in 185.573 CPU sec, 5.904 real sec
[M::process] read 720020 sequences (100000153 bp) in 1.895 CPU sec, 1.906 real sec...
[M::mem_process_seqs] Processed 719866 reads in 130.986 CPU sec, 4.147 real sec
sorting block 33, #reads = 1091186 mem = 536881526 peak = 937869312
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (22, 290319, 31, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (128, 478, 636)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1652)
[M::mem_pestat] mean and std.dev: (422.00, 356.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2160)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 196, 299)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 625)
[M::mem_pestat] mean and std.dev: (226.61, 118.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 788)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (111, 501, 2942)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8604)
[M::mem_pestat] mean and std.dev: (1565.19, 1820.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11435)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (213, 308, 740)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1794)
[M::mem_pestat] mean and std.dev: (371.50, 237.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2321)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 719244 sequences (100000022 bp) in 2.960 CPU sec, 3.020 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 290715, 13, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (146, 246, 778)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2042)
[M::mem_pestat] mean and std.dev: (507.09, 513.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2674)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 196, 297)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 619)
[M::mem_pestat] mean and std.dev: (225.69, 118.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 780)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (90, 360, 1780)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5160)
[M::mem_pestat] mean and std.dev: (846.00, 1145.76)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6850)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (216, 413, 2416)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6816)
[M::mem_pestat] mean and std.dev: (1225.36, 1630.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9016)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 718894 sequences (100000156 bp) in 2.220 CPU sec, 2.232 real sec...
[M::mem_process_seqs] Processed 719682 reads in 186.630 CPU sec, 5.905 real sec
sorting block 34, #reads = 1091628 mem = 536882327 peak = 937869312
[M::mem_process_seqs] Processed 720020 reads in 139.889 CPU sec, 4.443 real sec
[M::process] read 718668 sequences (100000036 bp) in 2.738 CPU sec, 2.850 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 290096, 20, 20)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 382, 1553)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4295)
[M::mem_pestat] mean and std.dev: (597.39, 635.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5666)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 197, 299)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 623)
[M::mem_pestat] mean and std.dev: (227.07, 118.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 785)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (397, 572, 3170)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8716)
[M::mem_pestat] mean and std.dev: (1498.90, 1555.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11489)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 214, 533)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1257)
[M::mem_pestat] mean and std.dev: (363.63, 299.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1619)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 719242 sequences (100000013 bp) in 2.170 CPU sec, 2.166 real sec...
[M::mem_process_seqs] Processed 718894 reads in 113.052 CPU sec, 3.568 real sec
sorting block 35, #reads = 1091014 mem = 536881864 peak = 937869312
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 290393, 26, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 229, 976)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2516)
[M::mem_pestat] mean and std.dev: (507.63, 519.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3286)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 197, 300)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 626)
[M::mem_pestat] mean and std.dev: (227.30, 119.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 789)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (83, 460, 964)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2726)
[M::mem_pestat] mean and std.dev: (529.33, 547.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3607)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 348, 446)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 972)
[M::mem_pestat] mean and std.dev: (286.24, 123.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1235)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 289819, 23, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 294, 676)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1670)
[M::mem_pestat] mean and std.dev: (442.91, 375.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2167)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 198, 302)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 632)
[M::mem_pestat] mean and std.dev: (228.48, 120.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 797)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (549, 1334, 1563)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3591)
[M::mem_pestat] mean and std.dev: (836.06, 568.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4605)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (232, 386, 1722)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4702)
[M::mem_pestat] mean and std.dev: (1088.18, 1238.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6192)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 718842 sequences (100000082 bp) in 2.362 CPU sec, 2.372 real sec...
[M::mem_process_seqs] Processed 719244 reads in 302.794 CPU sec, 9.597 real sec
sorting block 36, #reads = 1090554 mem = 536884804 peak = 1017036800
[M::mem_process_seqs] Processed 718668 reads in 164.207 CPU sec, 5.241 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 289753, 20, 23)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 227, 822)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2082)
[M::mem_pestat] mean and std.dev: (467.41, 446.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2712)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 197, 300)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 626)
[M::mem_pestat] mean and std.dev: (227.27, 119.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 789)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (180, 1225, 1463)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4029)
[M::mem_pestat] mean and std.dev: (881.47, 711.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5312)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (147, 242, 406)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 924)
[M::mem_pestat] mean and std.dev: (278.76, 184.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1183)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 719082 sequences (100000216 bp) in 3.274 CPU sec, 3.422 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 290304, 28, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (130, 252, 952)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2596)
[M::mem_pestat] mean and std.dev: (431.17, 468.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3418)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 198, 301)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 629)
[M::mem_pestat] mean and std.dev: (228.29, 120.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 793)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (318, 790, 1748)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4608)
[M::mem_pestat] mean and std.dev: (880.38, 840.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6038)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (243, 450, 1304)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3426)
[M::mem_pestat] mean and std.dev: (591.49, 451.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4487)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 721766 sequences (100000042 bp) in 1.970 CPU sec, 1.967 real sec...
[M::mem_process_seqs] Processed 719242 reads in 198.195 CPU sec, 6.279 real sec
sorting block 37, #reads = 1089599 mem = 536877111 peak = 1017036800
[M::mem_process_seqs] Processed 718842 reads in 146.182 CPU sec, 4.666 real sec
sorting block 38, #reads = 1088091 mem = 536880883 peak = 1017036800
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 290003, 19, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 253, 610)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1486)
[M::mem_pestat] mean and std.dev: (368.24, 255.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1924)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 197, 302)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 632)
[M::mem_pestat] mean and std.dev: (228.58, 121.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 797)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (692, 808, 1370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2726)
[M::mem_pestat] mean and std.dev: (957.53, 395.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3404)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 278, 1046)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2726)
[M::mem_pestat] mean and std.dev: (361.87, 319.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3566)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725396 sequences (100000033 bp) in 2.743 CPU sec, 2.879 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 291170, 15, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 265, 371)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 741)
[M::mem_pestat] mean and std.dev: (262.48, 108.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 926)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 193, 295)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 615)
[M::mem_pestat] mean and std.dev: (223.34, 117.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 775)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (455, 653, 808)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1514)
[M::mem_pestat] mean and std.dev: (593.54, 337.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1944)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (120, 267, 954)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2622)
[M::mem_pestat] mean and std.dev: (461.00, 489.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3456)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725272 sequences (100000280 bp) in 2.389 CPU sec, 2.387 real sec...
[M::mem_process_seqs] Processed 719082 reads in 203.027 CPU sec, 6.432 real sec
[M::mem_process_seqs] Processed 721766 reads in 143.006 CPU sec, 4.533 real sec
sorting block 39, #reads = 1088934 mem = 536881274 peak = 1017036800
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 292190, 16, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 428, 1570)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4384)
[M::mem_pestat] mean and std.dev: (625.21, 640.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5791)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 188, 287)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 597)
[M::mem_pestat] mean and std.dev: (217.76, 114.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 752)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (43, 314, 670)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1924)
[M::mem_pestat] mean and std.dev: (455.88, 445.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2551)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (205, 335, 431)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 883)
[M::mem_pestat] mean and std.dev: (330.62, 184.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1109)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724192 sequences (100000050 bp) in 2.799 CPU sec, 2.917 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (17, 292513, 11, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (273, 313, 1658)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4428)
[M::mem_pestat] mean and std.dev: (659.06, 638.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5813)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 189, 288)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 600)
[M::mem_pestat] mean and std.dev: (218.68, 114.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 756)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (356, 1828, 2700)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7388)
[M::mem_pestat] mean and std.dev: (1154.44, 1043.70)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9732)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 289, 810)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2068)
[M::mem_pestat] mean and std.dev: (435.41, 428.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2697)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724072 sequences (100000219 bp) in 2.259 CPU sec, 2.265 real sec...
[M::mem_process_seqs] Processed 725396 reads in 198.004 CPU sec, 6.284 real sec
[M::mem_process_seqs] Processed 725272 reads in 137.136 CPU sec, 4.355 real sec
sorting block 40, #reads = 1091983 mem = 536881401 peak = 1017036800
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 291739, 22, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 255, 545)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1303)
[M::mem_pestat] mean and std.dev: (299.00, 216.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1682)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 190, 291)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 607)
[M::mem_pestat] mean and std.dev: (220.31, 116.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 765)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (60, 372, 1531)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4473)
[M::mem_pestat] mean and std.dev: (627.05, 783.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5944)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 280, 651)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1553)
[M::mem_pestat] mean and std.dev: (390.87, 265.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2004)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722920 sequences (100000107 bp) in 3.025 CPU sec, 3.157 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 292120, 14, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (123, 222, 440)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1074)
[M::mem_pestat] mean and std.dev: (292.10, 218.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1391)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 191, 292)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 610)
[M::mem_pestat] mean and std.dev: (221.26, 116.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 769)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (290, 340, 595)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1205)
[M::mem_pestat] mean and std.dev: (471.36, 327.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1783)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 262, 938)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2458)
[M::mem_pestat] mean and std.dev: (355.38, 307.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3218)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 721904 sequences (100000300 bp) in 2.129 CPU sec, 2.125 real sec...
[M::mem_process_seqs] Processed 724192 reads in 199.160 CPU sec, 6.330 real sec
sorting block 41, #reads = 1095265 mem = 536878559 peak = 1017036800
[M::mem_process_seqs] Processed 724072 reads in 139.500 CPU sec, 4.445 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 291550, 29, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (135, 227, 1311)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3663)
[M::mem_pestat] mean and std.dev: (811.56, 945.66)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4839)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 192, 295)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 617)
[M::mem_pestat] mean and std.dev: (223.26, 118.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 778)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (83, 604, 780)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2174)
[M::mem_pestat] mean and std.dev: (549.72, 397.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2871)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 297, 711)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1771)
[M::mem_pestat] mean and std.dev: (353.07, 263.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2301)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 42, #reads = 1095274 mem = 536877922 peak = 1017036800
[M::process] read 721698 sequences (100000080 bp) in 3.406 CPU sec, 3.522 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 290931, 19, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 320, 438)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 964)
[M::mem_pestat] mean and std.dev: (273.46, 130.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1227)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 194, 298)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 626)
[M::mem_pestat] mean and std.dev: (225.62, 120.06)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 790)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (477, 594, 1714)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4188)
[M::mem_pestat] mean and std.dev: (1035.16, 890.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5425)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 297, 996)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2612)
[M::mem_pestat] mean and std.dev: (497.00, 501.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3420)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 722920 reads in 200.814 CPU sec, 6.380 real sec
[M::process] read 721490 sequences (100000031 bp) in 2.401 CPU sec, 2.409 real sec...
[M::mem_process_seqs] Processed 721904 reads in 140.940 CPU sec, 4.463 real sec
sorting block 43, #reads = 1093696 mem = 536880995 peak = 1017036800
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (21, 290961, 18, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (227, 1207, 2093)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5825)
[M::mem_pestat] mean and std.dev: (1201.63, 1206.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7691)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 194, 298)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 624)
[M::mem_pestat] mean and std.dev: (225.61, 119.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 787)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (274, 319, 853)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2011)
[M::mem_pestat] mean and std.dev: (418.33, 275.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2590)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (274, 395, 1096)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2740)
[M::mem_pestat] mean and std.dev: (616.64, 554.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3562)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 721154 sequences (100000062 bp) in 3.129 CPU sec, 3.284 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 291008, 8, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (193, 314, 1240)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3334)
[M::mem_pestat] mean and std.dev: (523.67, 597.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4381)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 195, 299)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 627)
[M::mem_pestat] mean and std.dev: (226.48, 120.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 791)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 354, 645)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1591)
[M::mem_pestat] mean and std.dev: (355.48, 243.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2064)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 722096 sequences (100000175 bp) in 2.109 CPU sec, 2.113 real sec...
[M::mem_process_seqs] Processed 721698 reads in 203.423 CPU sec, 6.466 real sec
[M::mem_process_seqs] Processed 721490 reads in 141.887 CPU sec, 4.514 real sec
sorting block 44, #reads = 1093269 mem = 536886431 peak = 1017036800
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (21, 291017, 16, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (127, 527, 2114)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6088)
[M::mem_pestat] mean and std.dev: (941.85, 1030.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8075)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 195, 300)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 630)
[M::mem_pestat] mean and std.dev: (227.18, 121.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 795)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (445, 1688, 1991)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5083)
[M::mem_pestat] mean and std.dev: (1329.19, 799.93)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6629)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 533, 1590)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4356)
[M::mem_pestat] mean and std.dev: (749.81, 719.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5739)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722218 sequences (100000107 bp) in 3.526 CPU sec, 3.663 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 290783, 23, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (144, 194, 629)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1599)
[M::mem_pestat] mean and std.dev: (298.38, 245.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2084)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 193, 294)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 614)
[M::mem_pestat] mean and std.dev: (222.92, 117.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 774)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (296, 566, 826)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1886)
[M::mem_pestat] mean and std.dev: (497.10, 363.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2416)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (178, 290, 524)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1216)
[M::mem_pestat] mean and std.dev: (288.05, 166.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1562)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 721154 reads in 209.298 CPU sec, 6.653 real sec
[M::process] read 720976 sequences (100000265 bp) in 2.386 CPU sec, 2.395 real sec...
sorting block 45, #reads = 1092190 mem = 536879596 peak = 1017036800
[M::mem_process_seqs] Processed 722096 reads in 141.956 CPU sec, 4.488 real sec
sorting block 46, #reads = 1091490 mem = 536879254 peak = 1017036800
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 291197, 17, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 346, 498)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1194)
[M::mem_pestat] mean and std.dev: (312.85, 183.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1542)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 192, 291)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 605)
[M::mem_pestat] mean and std.dev: (221.46, 115.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 762)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 549, 1420)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3944)
[M::mem_pestat] mean and std.dev: (569.13, 480.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5206)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 275, 952)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2460)
[M::mem_pestat] mean and std.dev: (593.70, 561.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3214)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 719828 sequences (100000121 bp) in 3.057 CPU sec, 3.212 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 290477, 25, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 523, 1185)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3149)
[M::mem_pestat] mean and std.dev: (709.58, 623.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4131)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 194, 293)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 609)
[M::mem_pestat] mean and std.dev: (223.07, 116.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 767)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (395, 861, 1849)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4757)
[M::mem_pestat] mean and std.dev: (986.29, 876.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6211)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 363, 5744)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 16872)
[M::mem_pestat] mean and std.dev: (1973.57, 2707.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 22436)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 719898 sequences (100000029 bp) in 2.807 CPU sec, 2.813 real sec...
[M::mem_process_seqs] Processed 722218 reads in 205.190 CPU sec, 6.509 real sec
[M::mem_process_seqs] Processed 720976 reads in 156.279 CPU sec, 4.978 real sec
sorting block 47, #reads = 1092377 mem = 536878688 peak = 1017036800
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 290399, 19, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 429, 675)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1631)
[M::mem_pestat] mean and std.dev: (414.52, 269.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2109)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 195, 296)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 616)
[M::mem_pestat] mean and std.dev: (224.72, 117.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 776)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 583, 1152)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3034)
[M::mem_pestat] mean and std.dev: (761.83, 748.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3975)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 247, 632)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1482)
[M::mem_pestat] mean and std.dev: (334.96, 183.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1907)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 719442 sequences (100000014 bp) in 3.499 CPU sec, 3.669 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 289950, 21, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (182, 330, 1027)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2717)
[M::mem_pestat] mean and std.dev: (516.09, 606.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3562)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 195, 296)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 616)
[M::mem_pestat] mean and std.dev: (224.95, 117.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 776)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 250, 608)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1500)
[M::mem_pestat] mean and std.dev: (395.05, 319.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1946)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (276, 516, 3402)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9654)
[M::mem_pestat] mean and std.dev: (1985.79, 2603.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12780)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 719828 reads in 213.480 CPU sec, 6.825 real sec
[M::process] read 718850 sequences (100000272 bp) in 2.126 CPU sec, 2.147 real sec...
[M::mem_process_seqs] Processed 719898 reads in 151.315 CPU sec, 4.816 real sec
sorting block 48, #reads = 1090399 mem = 536880244 peak = 1017036800
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 290343, 17, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 305, 865)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2291)
[M::mem_pestat] mean and std.dev: (492.55, 557.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3004)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 197, 297)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 619)
[M::mem_pestat] mean and std.dev: (225.72, 117.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 780)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (438, 906, 1455)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3489)
[M::mem_pestat] mean and std.dev: (977.81, 648.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4506)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (191, 494, 1334)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3620)
[M::mem_pestat] mean and std.dev: (683.66, 567.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4763)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 718646 sequences (100000135 bp) in 3.724 CPU sec, 4.080 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 290018, 13, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 392, 938)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2484)
[M::mem_pestat] mean and std.dev: (447.79, 383.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3257)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 197, 297)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 617)
[M::mem_pestat] mean and std.dev: (225.76, 116.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 777)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (456, 570, 1103)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2397)
[M::mem_pestat] mean and std.dev: (729.58, 513.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3044)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 394, 1527)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4189)
[M::mem_pestat] mean and std.dev: (735.17, 738.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5520)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 719442 reads in 211.567 CPU sec, 6.773 real sec
sorting block 49, #reads = 1089200 mem = 536880418 peak = 1017036800
[M::mem_process_seqs] Processed 718850 reads in 148.965 CPU sec, 4.733 real sec
[M::process] read 719076 sequences (100000022 bp) in 2.877 CPU sec, 3.019 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (21, 289891, 22, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (163, 277, 1528)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4258)
[M::mem_pestat] mean and std.dev: (705.24, 892.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5623)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 197, 300)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 626)
[M::mem_pestat] mean and std.dev: (227.47, 118.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 789)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (542, 736, 1275)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2741)
[M::mem_pestat] mean and std.dev: (654.89, 336.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3474)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 253, 406)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 842)
[M::mem_pestat] mean and std.dev: (258.90, 124.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1060)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 50, #reads = 1089888 mem = 536877392 peak = 1017036800
[M::process] read 718974 sequences (100000136 bp) in 3.391 CPU sec, 3.558 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 289865, 13, 22)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (223, 421, 744)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1786)
[M::mem_pestat] mean and std.dev: (420.75, 252.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2307)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 197, 299)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 625)
[M::mem_pestat] mean and std.dev: (226.84, 119.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 788)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (39, 1362, 3776)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 11250)
[M::mem_pestat] mean and std.dev: (1668.69, 1921.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14987)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (188, 347, 864)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2216)
[M::mem_pestat] mean and std.dev: (422.68, 354.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2892)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 718646 reads in 212.509 CPU sec, 6.789 real sec
[M::mem_process_seqs] Processed 719076 reads in 150.623 CPU sec, 4.755 real sec
[M::process] read 721406 sequences (100000225 bp) in 2.872 CPU sec, 2.944 real sec...
sorting block 51, #reads = 1088061 mem = 536879537 peak = 1017036800
[M::process] read 730422 sequences (100000155 bp) in 3.259 CPU sec, 3.498 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 291290, 23, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (198, 295, 1348)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3648)
[M::mem_pestat] mean and std.dev: (316.07, 244.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4798)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 194, 296)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 618)
[M::mem_pestat] mean and std.dev: (224.28, 118.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 779)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (311, 582, 1197)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2969)
[M::mem_pestat] mean and std.dev: (749.14, 628.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3855)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (165, 372, 627)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1551)
[M::mem_pestat] mean and std.dev: (367.39, 216.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2013)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 721406 reads in 127.584 CPU sec, 4.025 real sec
[M::process] read 728194 sequences (100000282 bp) in 2.570 CPU sec, 2.593 real sec...
sorting block 52, #reads = 1088867 mem = 536879945 peak = 1017036800
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 290174, 17, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 239, 657)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1583)
[M::mem_pestat] mean and std.dev: (393.03, 353.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2046)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 197, 302)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 632)
[M::mem_pestat] mean and std.dev: (228.65, 121.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 797)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (95, 510, 1565)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4505)
[M::mem_pestat] mean and std.dev: (645.19, 635.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5975)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (156, 280, 408)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 912)
[M::mem_pestat] mean and std.dev: (300.61, 164.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1164)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 294511, 12, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 194, 390)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 824)
[M::mem_pestat] mean and std.dev: (220.00, 101.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1041)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 180, 265)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 539)
[M::mem_pestat] mean and std.dev: (203.61, 102.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 676)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (231, 424, 1402)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3744)
[M::mem_pestat] mean and std.dev: (768.75, 739.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4915)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 405, 1751)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4851)
[M::mem_pestat] mean and std.dev: (1065.16, 1320.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6401)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 718974 reads in 343.627 CPU sec, 10.955 real sec
[M::process] read 725676 sequences (100000063 bp) in 2.722 CPU sec, 2.752 real sec...
[M::mem_process_seqs] Processed 730422 reads in 186.780 CPU sec, 5.988 real sec
sorting block 53, #reads = 1089006 mem = 536879624 peak = 1017036800
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 293837, 13, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 300, 1161)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3093)
[M::mem_pestat] mean and std.dev: (722.11, 723.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4059)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 183, 274)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 564)
[M::mem_pestat] mean and std.dev: (209.34, 107.54)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 709)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (105, 275, 1097)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3081)
[M::mem_pestat] mean and std.dev: (533.83, 694.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4073)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 279, 1118)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2950)
[M::mem_pestat] mean and std.dev: (568.33, 671.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3866)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 724422 sequences (100000048 bp) in 3.191 CPU sec, 3.337 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 292894, 22, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 313, 897)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2343)
[M::mem_pestat] mean and std.dev: (571.94, 450.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3066)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 187, 283)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 587)
[M::mem_pestat] mean and std.dev: (215.35, 112.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 739)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (70, 271, 522)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1426)
[M::mem_pestat] mean and std.dev: (267.39, 318.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1878)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (234, 312, 727)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1713)
[M::mem_pestat] mean and std.dev: (463.97, 348.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2206)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723758 sequences (100000165 bp) in 2.356 CPU sec, 2.358 real sec...
[M::mem_process_seqs] Processed 728194 reads in 207.051 CPU sec, 6.577 real sec
sorting block 54, #reads = 1094762 mem = 536879004 peak = 1017036800
[M::mem_process_seqs] Processed 725676 reads in 148.962 CPU sec, 4.738 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 291940, 27, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (281, 889, 1128)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2822)
[M::mem_pestat] mean and std.dev: (705.81, 544.58)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3669)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 188, 285)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 591)
[M::mem_pestat] mean and std.dev: (217.12, 113.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 744)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (602, 651, 2415)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6041)
[M::mem_pestat] mean and std.dev: (1535.59, 1403.37)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7854)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (190, 334, 662)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1606)
[M::mem_pestat] mean and std.dev: (358.68, 214.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2078)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723284 sequences (100000090 bp) in 2.670 CPU sec, 2.814 real sec...
[M::process] read 723376 sequences (100000291 bp) in 2.203 CPU sec, 2.218 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20, 292233, 12, 23)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (159, 219, 390)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 852)
[M::mem_pestat] mean and std.dev: (259.16, 124.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1083)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 190, 289)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 601)
[M::mem_pestat] mean and std.dev: (219.61, 115.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 757)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (277, 1130, 1437)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3757)
[M::mem_pestat] mean and std.dev: (1142.25, 998.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5135)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (196, 477, 839)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2125)
[M::mem_pestat] mean and std.dev: (482.29, 313.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2768)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 724422 reads in 204.679 CPU sec, 6.507 real sec
sorting block 55, #reads = 1093836 mem = 536879805 peak = 1017036800
[M::mem_process_seqs] Processed 723758 reads in 142.381 CPU sec, 4.535 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 291835, 17, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 283, 498)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1164)
[M::mem_pestat] mean and std.dev: (308.44, 200.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1497)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 191, 291)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 607)
[M::mem_pestat] mean and std.dev: (221.31, 117.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 765)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (247, 727, 1295)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3391)
[M::mem_pestat] mean and std.dev: (685.53, 569.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4439)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (186, 330, 772)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1944)
[M::mem_pestat] mean and std.dev: (421.80, 313.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2530)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 56, #reads = 1094280 mem = 536879410 peak = 1057857536
[M::process] read 722378 sequences (100000184 bp) in 3.601 CPU sec, 3.762 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20, 291885, 17, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 204, 337)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 667)
[M::mem_pestat] mean and std.dev: (259.05, 146.35)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 844)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 191, 291)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 607)
[M::mem_pestat] mean and std.dev: (221.16, 117.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 765)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (395, 1319, 4726)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13388)
[M::mem_pestat] mean and std.dev: (2394.65, 2295.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17719)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (157, 358, 743)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1915)
[M::mem_pestat] mean and std.dev: (519.26, 452.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2501)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 723284 reads in 209.796 CPU sec, 6.665 real sec
[M::process] read 721730 sequences (100000221 bp) in 2.498 CPU sec, 2.506 real sec...
[M::mem_process_seqs] Processed 723376 reads in 148.602 CPU sec, 4.710 real sec
sorting block 57, #reads = 1092685 mem = 536877555 peak = 1057857536
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 290830, 14, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (179, 297, 1657)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4613)
[M::mem_pestat] mean and std.dev: (991.42, 1289.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6151)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 192, 293)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 611)
[M::mem_pestat] mean and std.dev: (222.34, 117.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 770)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (790, 1424, 1846)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3958)
[M::mem_pestat] mean and std.dev: (1040.36, 669.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5014)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (200, 359, 881)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2243)
[M::mem_pestat] mean and std.dev: (619.41, 606.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3044)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720902 sequences (100000179 bp) in 3.875 CPU sec, 4.043 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 291061, 12, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (197, 238, 427)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 887)
[M::mem_pestat] mean and std.dev: (249.62, 121.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1117)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 193, 295)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 615)
[M::mem_pestat] mean and std.dev: (224.11, 118.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 775)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (267, 681, 1472)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3882)
[M::mem_pestat] mean and std.dev: (861.42, 1005.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5087)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (220, 436, 1279)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3397)
[M::mem_pestat] mean and std.dev: (922.74, 1018.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4996)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 722378 reads in 211.213 CPU sec, 6.717 real sec
[M::process] read 720878 sequences (100000263 bp) in 2.458 CPU sec, 2.476 real sec...
[M::mem_process_seqs] Processed 721730 reads in 149.665 CPU sec, 4.736 real sec
sorting block 58, #reads = 1090750 mem = 536877144 peak = 1057857536
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 290491, 15, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (220, 508, 1013)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2599)
[M::mem_pestat] mean and std.dev: (585.79, 424.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3392)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 194, 296)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 618)
[M::mem_pestat] mean and std.dev: (224.39, 118.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 779)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (110, 1276, 2140)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6200)
[M::mem_pestat] mean and std.dev: (1271.60, 1108.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8230)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (174, 245, 695)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1737)
[M::mem_pestat] mean and std.dev: (392.11, 328.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2258)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 721076 sequences (100000197 bp) in 3.177 CPU sec, 3.376 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 289916, 15, 54)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (260, 319, 675)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1505)
[M::mem_pestat] mean and std.dev: (364.84, 226.77)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1920)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 194, 296)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 618)
[M::mem_pestat] mean and std.dev: (224.74, 118.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 779)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (116, 806, 4876)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 14396)
[M::mem_pestat] mean and std.dev: (2114.27, 2607.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 19156)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 370, 751)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1857)
[M::mem_pestat] mean and std.dev: (483.08, 410.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2410)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720006 sequences (100000248 bp) in 2.527 CPU sec, 2.528 real sec...
[M::mem_process_seqs] Processed 720902 reads in 216.131 CPU sec, 7.090 real sec
sorting block 59, #reads = 1089596 mem = 536882044 peak = 1057857536
[M::mem_process_seqs] Processed 720878 reads in 147.664 CPU sec, 4.683 real sec
sorting block 60, #reads = 1088914 mem = 536882393 peak = 1067515904
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 290707, 23, 55)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (265, 441, 742)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1696)
[M::mem_pestat] mean and std.dev: (480.03, 332.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2173)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 194, 295)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 615)
[M::mem_pestat] mean and std.dev: (224.20, 118.22)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 775)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (662, 879, 1866)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4274)
[M::mem_pestat] mean and std.dev: (1037.43, 808.32)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5478)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 408, 908)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2316)
[M::mem_pestat] mean and std.dev: (519.34, 411.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3020)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720214 sequences (100000157 bp) in 3.388 CPU sec, 3.502 real sec...
[M::process] read 719728 sequences (100000275 bp) in 1.856 CPU sec, 1.865 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 290402, 11, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (144, 287, 479)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1149)
[M::mem_pestat] mean and std.dev: (284.44, 210.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1484)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 195, 296)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 616)
[M::mem_pestat] mean and std.dev: (224.98, 118.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 776)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (87, 218, 399)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1023)
[M::mem_pestat] mean and std.dev: (224.00, 175.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1335)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 301, 1032)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2684)
[M::mem_pestat] mean and std.dev: (535.64, 478.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3510)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 721076 reads in 211.602 CPU sec, 6.725 real sec
[M::mem_process_seqs] Processed 720006 reads in 143.266 CPU sec, 4.556 real sec
sorting block 61, #reads = 1088259 mem = 536877132 peak = 1067515904
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 290814, 24, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 467, 838)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2108)
[M::mem_pestat] mean and std.dev: (376.38, 255.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2743)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 195, 297)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 619)
[M::mem_pestat] mean and std.dev: (225.59, 119.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 780)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 1207, 3107)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8879)
[M::mem_pestat] mean and std.dev: (1224.00, 1282.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 11765)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 259, 1815)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5067)
[M::mem_pestat] mean and std.dev: (694.71, 1004.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6693)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 719416 sequences (100000199 bp) in 3.342 CPU sec, 3.486 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 290092, 27, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (206, 473, 1006)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2606)
[M::mem_pestat] mean and std.dev: (728.82, 697.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3519)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 196, 298)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 622)
[M::mem_pestat] mean and std.dev: (226.07, 118.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 784)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (176, 563, 1729)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4835)
[M::mem_pestat] mean and std.dev: (925.48, 863.79)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6388)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 303, 769)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1973)
[M::mem_pestat] mean and std.dev: (457.34, 463.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2575)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 719824 sequences (100000280 bp) in 2.420 CPU sec, 2.419 real sec...
[M::mem_process_seqs] Processed 720214 reads in 205.126 CPU sec, 6.490 real sec
[M::mem_process_seqs] Processed 719728 reads in 143.348 CPU sec, 4.541 real sec
sorting block 62, #reads = 1088599 mem = 536877916 peak = 1067515904
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 290163, 21, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 398, 759)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1885)
[M::mem_pestat] mean and std.dev: (308.57, 183.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2448)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 196, 298)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 622)
[M::mem_pestat] mean and std.dev: (226.45, 119.04)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 784)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (435, 772, 1522)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3696)
[M::mem_pestat] mean and std.dev: (909.05, 688.57)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4783)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 435, 910)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2368)
[M::mem_pestat] mean and std.dev: (522.97, 448.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3097)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 719392 sequences (100000298 bp) in 2.944 CPU sec, 3.204 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 290122, 10, 37)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (201, 357, 685)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1653)
[M::mem_pestat] mean and std.dev: (342.49, 203.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2137)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 195, 298)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 622)
[M::mem_pestat] mean and std.dev: (225.97, 119.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 784)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (167, 425, 561)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1349)
[M::mem_pestat] mean and std.dev: (332.56, 188.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1743)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (183, 320, 1389)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3801)
[M::mem_pestat] mean and std.dev: (574.36, 625.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5007)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 719522 sequences (100000016 bp) in 2.500 CPU sec, 2.493 real sec...
[M::mem_process_seqs] Processed 719416 reads in 209.199 CPU sec, 6.700 real sec
sorting block 63, #reads = 1086753 mem = 536877366 peak = 1067515904
[M::mem_process_seqs] Processed 719824 reads in 146.149 CPU sec, 4.640 real sec
sorting block 64, #reads = 1087448 mem = 536879479 peak = 1081561088
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28, 289871, 18, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (211, 352, 516)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1126)
[M::mem_pestat] mean and std.dev: (325.00, 157.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1431)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 197, 300)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 628)
[M::mem_pestat] mean and std.dev: (227.43, 120.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 792)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (67, 344, 1025)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2941)
[M::mem_pestat] mean and std.dev: (680.22, 820.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3963)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (204, 351, 706)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1710)
[M::mem_pestat] mean and std.dev: (404.63, 317.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2212)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 730060 sequences (100000268 bp) in 3.157 CPU sec, 3.299 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 290007, 17, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 258, 832)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2182)
[M::mem_pestat] mean and std.dev: (445.88, 376.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2857)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 197, 301)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 631)
[M::mem_pestat] mean and std.dev: (227.93, 121.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 796)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 394, 1348)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3612)
[M::mem_pestat] mean and std.dev: (689.94, 643.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4744)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 378, 670)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1554)
[M::mem_pestat] mean and std.dev: (487.52, 392.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2058)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 732808 sequences (100000239 bp) in 2.509 CPU sec, 2.511 real sec...
[M::mem_process_seqs] Processed 719392 reads in 208.920 CPU sec, 6.619 real sec
[M::mem_process_seqs] Processed 719522 reads in 145.140 CPU sec, 4.593 real sec
sorting block 65, #reads = 1087660 mem = 536880326 peak = 1081561088
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 293734, 18, 20)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (141, 272, 567)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1419)
[M::mem_pestat] mean and std.dev: (346.19, 296.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1845)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 180, 268)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 546)
[M::mem_pestat] mean and std.dev: (205.22, 103.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 685)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (52, 546, 1267)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3697)
[M::mem_pestat] mean and std.dev: (651.65, 703.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4912)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (148, 487, 1048)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2848)
[M::mem_pestat] mean and std.dev: (474.33, 379.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3748)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 731402 sequences (100000036 bp) in 2.930 CPU sec, 3.021 real sec...
[M::process] read 728660 sequences (100000077 bp) in 1.950 CPU sec, 1.953 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 295787, 15, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (131, 292, 1097)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3029)
[M::mem_pestat] mean and std.dev: (600.56, 769.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3995)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (127, 177, 259)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 523)
[M::mem_pestat] mean and std.dev: (199.37, 98.50)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 655)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (271, 664, 943)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2287)
[M::mem_pestat] mean and std.dev: (707.07, 543.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2959)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (351, 446, 1042)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2424)
[M::mem_pestat] mean and std.dev: (615.92, 477.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3115)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 730060 reads in 221.812 CPU sec, 7.051 real sec
[M::mem_process_seqs] Processed 732808 reads in 153.863 CPU sec, 4.905 real sec
sorting block 66, #reads = 1088913 mem = 536880248 peak = 1081561088
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 294588, 13, 22)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (151, 305, 788)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2062)
[M::mem_pestat] mean and std.dev: (466.20, 478.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2699)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 178, 263)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 533)
[M::mem_pestat] mean and std.dev: (202.57, 101.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 668)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (152, 343, 796)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2084)
[M::mem_pestat] mean and std.dev: (410.33, 300.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2728)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (189, 241, 270)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (27, 432)
[M::mem_pestat] mean and std.dev: (230.10, 79.88)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 550)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 728020 sequences (100000220 bp) in 3.015 CPU sec, 3.106 real sec...
[M::process] read 727040 sequences (100000037 bp) in 2.370 CPU sec, 2.367 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 294221, 14, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (282, 626, 2366)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6534)
[M::mem_pestat] mean and std.dev: (1260.66, 1362.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8618)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 182, 272)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 558)
[M::mem_pestat] mean and std.dev: (208.47, 106.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 701)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (126, 1045, 1781)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5091)
[M::mem_pestat] mean and std.dev: (942.14, 776.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6746)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (202, 257, 546)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1234)
[M::mem_pestat] mean and std.dev: (344.33, 227.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1578)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 731402 reads in 221.688 CPU sec, 7.040 real sec
sorting block 67, #reads = 1093789 mem = 536877905 peak = 1081561088
[M::mem_process_seqs] Processed 728660 reads in 160.101 CPU sec, 5.118 real sec
sorting block 68, #reads = 1090975 mem = 536880929 peak = 1081561088
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (21, 293799, 13, 19)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (254, 762, 1357)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3563)
[M::mem_pestat] mean and std.dev: (758.00, 600.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4666)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 183, 274)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 562)
[M::mem_pestat] mean and std.dev: (210.27, 108.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 706)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (650, 1030, 3635)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9605)
[M::mem_pestat] mean and std.dev: (1797.92, 1739.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12590)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (260, 457, 953)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2339)
[M::mem_pestat] mean and std.dev: (522.50, 470.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3032)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726270 sequences (100000019 bp) in 2.669 CPU sec, 2.795 real sec...
[M::process] read 725636 sequences (100000165 bp) in 2.360 CPU sec, 2.359 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 293699, 18, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (283, 651, 822)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1900)
[M::mem_pestat] mean and std.dev: (564.13, 329.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2439)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 184, 278)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 572)
[M::mem_pestat] mean and std.dev: (212.38, 110.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 719)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (171, 787, 1680)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4698)
[M::mem_pestat] mean and std.dev: (844.94, 772.51)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6207)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (141, 260, 993)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2697)
[M::mem_pestat] mean and std.dev: (483.96, 568.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3549)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 728020 reads in 211.827 CPU sec, 6.728 real sec
[M::mem_process_seqs] Processed 727040 reads in 146.937 CPU sec, 4.673 real sec
sorting block 69, #reads = 1091255 mem = 536879573 peak = 1081561088
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 293755, 11, 39)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 248, 820)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2116)
[M::mem_pestat] mean and std.dev: (380.87, 395.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2764)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 186, 281)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 581)
[M::mem_pestat] mean and std.dev: (214.14, 111.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 731)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (187, 738, 1381)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3769)
[M::mem_pestat] mean and std.dev: (870.00, 689.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4963)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 294, 768)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1920)
[M::mem_pestat] mean and std.dev: (387.41, 371.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2496)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725372 sequences (100000063 bp) in 2.998 CPU sec, 3.064 real sec...
[M::process] read 724272 sequences (100000066 bp) in 2.480 CPU sec, 2.483 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 292451, 14, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (204, 1165, 1709)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4719)
[M::mem_pestat] mean and std.dev: (1079.74, 934.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6224)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 187, 284)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 588)
[M::mem_pestat] mean and std.dev: (216.37, 113.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 740)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (144, 275, 1495)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4197)
[M::mem_pestat] mean and std.dev: (729.62, 961.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5548)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (164, 251, 426)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 950)
[M::mem_pestat] mean and std.dev: (282.96, 165.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1212)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 726270 reads in 209.758 CPU sec, 6.635 real sec
sorting block 70, #reads = 1092818 mem = 536884760 peak = 1081561088
[M::mem_process_seqs] Processed 725636 reads in 147.949 CPU sec, 4.702 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 292754, 13, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 306, 647)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1535)
[M::mem_pestat] mean and std.dev: (428.64, 365.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1979)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 188, 285)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 591)
[M::mem_pestat] mean and std.dev: (216.79, 113.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 744)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (205, 549, 1230)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3280)
[M::mem_pestat] mean and std.dev: (531.18, 462.90)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4305)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (245, 545, 1026)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2588)
[M::mem_pestat] mean and std.dev: (492.60, 367.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3369)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722892 sequences (100000203 bp) in 2.974 CPU sec, 3.076 real sec...
[M::process] read 721938 sequences (100000212 bp) in 2.428 CPU sec, 2.423 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 292052, 16, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (219, 272, 486)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1020)
[M::mem_pestat] mean and std.dev: (302.81, 158.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1287)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 189, 289)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 603)
[M::mem_pestat] mean and std.dev: (219.54, 115.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 760)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (51, 269, 1213)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3537)
[M::mem_pestat] mean and std.dev: (325.85, 383.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4699)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 449, 602)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1350)
[M::mem_pestat] mean and std.dev: (433.98, 272.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1724)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 725372 reads in 216.337 CPU sec, 6.883 real sec
sorting block 71, #reads = 1091142 mem = 536879107 peak = 1081561088
[M::mem_process_seqs] Processed 724272 reads in 149.088 CPU sec, 4.740 real sec
sorting block 72, #reads = 1090897 mem = 536877551 peak = 1134522368
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 291098, 18, 42)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (194, 255, 453)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 971)
[M::mem_pestat] mean and std.dev: (290.69, 160.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1230)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 191, 291)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 607)
[M::mem_pestat] mean and std.dev: (221.22, 116.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 765)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (17, 293, 653)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1925)
[M::mem_pestat] mean and std.dev: (443.24, 550.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2644)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (207, 347, 686)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1644)
[M::mem_pestat] mean and std.dev: (418.38, 334.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2123)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 721596 sequences (100000130 bp) in 3.243 CPU sec, 3.345 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 291434, 21, 27)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 200, 932)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2496)
[M::mem_pestat] mean and std.dev: (427.17, 498.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3278)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 192, 292)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 608)
[M::mem_pestat] mean and std.dev: (222.14, 116.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 766)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (324, 1134, 4397)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12543)
[M::mem_pestat] mean and std.dev: (2046.86, 2039.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 16616)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (181, 250, 515)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1183)
[M::mem_pestat] mean and std.dev: (333.62, 241.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1517)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720666 sequences (100000044 bp) in 2.607 CPU sec, 2.607 real sec...
[M::mem_process_seqs] Processed 722892 reads in 228.380 CPU sec, 7.285 real sec
[M::mem_process_seqs] Processed 721938 reads in 156.640 CPU sec, 4.977 real sec
sorting block 73, #reads = 1088779 mem = 536880763 peak = 1134522368
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 290765, 27, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (136, 236, 642)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1654)
[M::mem_pestat] mean and std.dev: (357.06, 307.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2160)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 193, 293)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 609)
[M::mem_pestat] mean and std.dev: (222.94, 117.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 767)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (133, 866, 1697)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4825)
[M::mem_pestat] mean and std.dev: (755.78, 901.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6389)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (265, 426, 1267)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3271)
[M::mem_pestat] mean and std.dev: (792.12, 630.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4273)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720778 sequences (100000009 bp) in 3.173 CPU sec, 3.265 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 290775, 15, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (192, 412, 4601)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13419)
[M::mem_pestat] mean and std.dev: (1718.24, 2341.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17828)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 194, 296)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 618)
[M::mem_pestat] mean and std.dev: (224.79, 118.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 779)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (221, 726, 1189)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3125)
[M::mem_pestat] mean and std.dev: (666.92, 657.78)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4093)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 411, 1330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3534)
[M::mem_pestat] mean and std.dev: (488.45, 437.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4636)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720316 sequences (100000068 bp) in 2.597 CPU sec, 2.599 real sec...
[M::mem_process_seqs] Processed 721596 reads in 224.073 CPU sec, 7.259 real sec
[M::mem_process_seqs] Processed 720666 reads in 156.486 CPU sec, 4.984 real sec
sorting block 74, #reads = 1088752 mem = 536877469 peak = 1134522368
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 290479, 13, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (170, 263, 1054)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2822)
[M::mem_pestat] mean and std.dev: (440.52, 480.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3706)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 194, 296)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 618)
[M::mem_pestat] mean and std.dev: (224.79, 118.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 779)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (291, 666, 1160)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2898)
[M::mem_pestat] mean and std.dev: (777.00, 661.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3767)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 539, 2180)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6128)
[M::mem_pestat] mean and std.dev: (1058.57, 1358.27)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8102)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 719194 sequences (100000220 bp) in 3.335 CPU sec, 3.488 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 290615, 24, 46)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 310, 513)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1149)
[M::mem_pestat] mean and std.dev: (275.42, 130.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1467)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 195, 296)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 618)
[M::mem_pestat] mean and std.dev: (224.92, 118.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 779)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (482, 800, 1748)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4280)
[M::mem_pestat] mean and std.dev: (941.21, 736.94)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5546)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 441, 983)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2547)
[M::mem_pestat] mean and std.dev: (619.00, 536.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3329)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 719562 sequences (100000026 bp) in 2.468 CPU sec, 2.475 real sec...
[M::mem_process_seqs] Processed 720778 reads in 219.363 CPU sec, 6.988 real sec
sorting block 75, #reads = 1088397 mem = 536878350 peak = 1134522368
[M::mem_process_seqs] Processed 720316 reads in 154.012 CPU sec, 4.897 real sec
sorting block 76, #reads = 1087784 mem = 536877849 peak = 1139822592
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 290014, 21, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (331, 623, 992)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2314)
[M::mem_pestat] mean and std.dev: (603.43, 430.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2975)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 197, 300)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 628)
[M::mem_pestat] mean and std.dev: (227.44, 120.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 792)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (129, 976, 1444)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4074)
[M::mem_pestat] mean and std.dev: (915.85, 819.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5389)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 361, 1123)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2973)
[M::mem_pestat] mean and std.dev: (664.16, 721.96)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3898)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720394 sequences (100000275 bp) in 3.642 CPU sec, 3.744 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 290438, 11, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (138, 186, 853)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2283)
[M::mem_pestat] mean and std.dev: (475.76, 497.55)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2998)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 196, 300)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 628)
[M::mem_pestat] mean and std.dev: (227.25, 120.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 792)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (86, 719, 4537)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13439)
[M::mem_pestat] mean and std.dev: (2322.00, 3019.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 17890)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (237, 397, 596)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1314)
[M::mem_pestat] mean and std.dev: (422.51, 234.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1673)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 719194 reads in 214.406 CPU sec, 6.816 real sec
[M::process] read 730272 sequences (100000203 bp) in 2.644 CPU sec, 2.648 real sec...
[M::mem_process_seqs] Processed 719562 reads in 150.571 CPU sec, 4.775 real sec
sorting block 77, #reads = 1088056 mem = 536881704 peak = 1139822592
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37, 290216, 17, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (195, 310, 595)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1395)
[M::mem_pestat] mean and std.dev: (331.45, 208.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1795)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 194, 295)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 615)
[M::mem_pestat] mean and std.dev: (224.05, 118.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 775)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (150, 271, 602)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1506)
[M::mem_pestat] mean and std.dev: (456.24, 410.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2100)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 409, 1018)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2630)
[M::mem_pestat] mean and std.dev: (544.32, 415.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3436)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 729542 sequences (100000106 bp) in 3.361 CPU sec, 3.504 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 294206, 22, 13)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (161, 231, 831)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2171)
[M::mem_pestat] mean and std.dev: (348.07, 375.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2841)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (128, 180, 268)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 548)
[M::mem_pestat] mean and std.dev: (205.61, 104.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 688)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (239, 485, 812)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1958)
[M::mem_pestat] mean and std.dev: (474.74, 426.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2531)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (158, 179, 580)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1424)
[M::mem_pestat] mean and std.dev: (306.58, 294.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1846)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 728152 sequences (100000181 bp) in 2.518 CPU sec, 2.523 real sec...
[M::mem_process_seqs] Processed 720394 reads in 234.413 CPU sec, 7.712 real sec
[M::mem_process_seqs] Processed 730272 reads in 162.683 CPU sec, 5.192 real sec
sorting block 78, #reads = 1087877 mem = 536879931 peak = 1139822592
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23, 294213, 10, 24)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (249, 431, 1490)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3972)
[M::mem_pestat] mean and std.dev: (643.05, 527.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5213)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 181, 271)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 555)
[M::mem_pestat] mean and std.dev: (207.47, 105.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 697)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (148, 461, 628)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1588)
[M::mem_pestat] mean and std.dev: (549.20, 514.10)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2606)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 242, 566)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1430)
[M::mem_pestat] mean and std.dev: (309.41, 259.42)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1862)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726494 sequences (100000152 bp) in 3.216 CPU sec, 3.343 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (19, 293953, 14, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (160, 191, 990)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2650)
[M::mem_pestat] mean and std.dev: (441.28, 424.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3480)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 183, 276)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 568)
[M::mem_pestat] mean and std.dev: (210.96, 108.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 714)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (346, 417, 859)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1885)
[M::mem_pestat] mean and std.dev: (477.42, 356.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2398)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (203, 350, 792)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1970)
[M::mem_pestat] mean and std.dev: (413.09, 300.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2559)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725250 sequences (100000100 bp) in 2.195 CPU sec, 2.207 real sec...
[M::mem_process_seqs] Processed 729542 reads in 214.957 CPU sec, 6.855 real sec
sorting block 79, #reads = 1088679 mem = 536878302 peak = 1139822592
[M::mem_process_seqs] Processed 728152 reads in 146.445 CPU sec, 4.858 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32, 293183, 13, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (166, 281, 1155)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3133)
[M::mem_pestat] mean and std.dev: (465.07, 576.69)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4122)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 186, 281)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 581)
[M::mem_pestat] mean and std.dev: (214.30, 111.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 731)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (491, 570, 1202)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2624)
[M::mem_pestat] mean and std.dev: (600.75, 400.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3335)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 308, 845)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2101)
[M::mem_pestat] mean and std.dev: (424.93, 437.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2729)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 80, #reads = 1097373 mem = 536877567 peak = 1139822592
[M::process] read 724840 sequences (100000151 bp) in 3.272 CPU sec, 3.390 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (19, 292873, 17, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 211, 263)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 473)
[M::mem_pestat] mean and std.dev: (179.53, 48.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 578)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 188, 284)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 588)
[M::mem_pestat] mean and std.dev: (216.66, 112.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 740)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (271, 306, 684)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1510)
[M::mem_pestat] mean and std.dev: (365.53, 220.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1923)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (295, 454, 966)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2308)
[M::mem_pestat] mean and std.dev: (561.03, 423.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2979)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 726494 reads in 209.003 CPU sec, 6.872 real sec
[M::process] read 723894 sequences (100000018 bp) in 2.704 CPU sec, 2.733 real sec...
[M::mem_process_seqs] Processed 725250 reads in 144.953 CPU sec, 4.602 real sec
sorting block 81, #reads = 1095645 mem = 536877454 peak = 1139822592
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (20, 292843, 9, 28)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (133, 205, 1411)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3967)
[M::mem_pestat] mean and std.dev: (509.94, 700.28)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5245)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 189, 287)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 597)
[M::mem_pestat] mean and std.dev: (218.20, 114.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 752)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (198, 342, 753)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1863)
[M::mem_pestat] mean and std.dev: (446.85, 301.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2418)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 724808 sequences (100000188 bp) in 3.320 CPU sec, 3.437 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 292813, 10, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (222, 782, 1297)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3447)
[M::mem_pestat] mean and std.dev: (635.00, 498.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4522)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 190, 289)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 601)
[M::mem_pestat] mean and std.dev: (219.89, 115.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 757)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (410, 672, 2014)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5222)
[M::mem_pestat] mean and std.dev: (997.10, 795.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6826)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (212, 329, 931)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2369)
[M::mem_pestat] mean and std.dev: (515.06, 477.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3088)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723922 sequences (100000217 bp) in 2.326 CPU sec, 2.329 real sec...
[M::mem_process_seqs] Processed 724840 reads in 223.155 CPU sec, 7.279 real sec
[M::mem_process_seqs] Processed 723894 reads in 157.656 CPU sec, 5.008 real sec
sorting block 82, #reads = 1095309 mem = 536878021 peak = 1139822592
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 292572, 7, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (196, 368, 950)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2458)
[M::mem_pestat] mean and std.dev: (596.12, 540.86)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3212)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 188, 286)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 594)
[M::mem_pestat] mean and std.dev: (217.75, 113.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 748)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (187, 258, 1531)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4219)
[M::mem_pestat] mean and std.dev: (926.45, 1166.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5593)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 723412 sequences (100000046 bp) in 3.127 CPU sec, 3.231 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31, 292825, 15, 14)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (175, 192, 1137)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3061)
[M::mem_pestat] mean and std.dev: (521.82, 696.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4023)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 190, 290)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 604)
[M::mem_pestat] mean and std.dev: (220.18, 115.56)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 761)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (307, 1000, 2241)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6109)
[M::mem_pestat] mean and std.dev: (1228.87, 1071.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8043)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (172, 265, 1330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3646)
[M::mem_pestat] mean and std.dev: (572.00, 528.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4804)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723894 sequences (100000187 bp) in 2.325 CPU sec, 2.328 real sec...
[M::mem_process_seqs] Processed 724808 reads in 200.007 CPU sec, 6.372 real sec
sorting block 83, #reads = 1092707 mem = 536881806 peak = 1139822592
[M::mem_process_seqs] Processed 723922 reads in 142.577 CPU sec, 4.543 real sec
sorting block 84, #reads = 1094583 mem = 536878216 peak = 1139822592
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 292083, 6, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (125, 208, 343)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 779)
[M::mem_pestat] mean and std.dev: (218.17, 114.62)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 997)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 190, 292)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 610)
[M::mem_pestat] mean and std.dev: (221.31, 116.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 769)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (193, 355, 800)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2014)
[M::mem_pestat] mean and std.dev: (382.26, 278.59)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2621)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 723098 sequences (100000145 bp) in 3.042 CPU sec, 3.166 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 291950, 13, 31)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (172, 209, 413)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 895)
[M::mem_pestat] mean and std.dev: (242.70, 156.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1136)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 189, 286)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 592)
[M::mem_pestat] mean and std.dev: (218.06, 112.95)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 745)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (99, 741, 1587)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4563)
[M::mem_pestat] mean and std.dev: (783.62, 712.82)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6051)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (219, 276, 719)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1719)
[M::mem_pestat] mean and std.dev: (389.14, 315.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2219)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 723064 sequences (100000081 bp) in 2.113 CPU sec, 2.117 real sec...
[M::mem_process_seqs] Processed 723412 reads in 210.726 CPU sec, 6.734 real sec
[M::mem_process_seqs] Processed 723894 reads in 146.646 CPU sec, 4.688 real sec
sorting block 85, #reads = 1093916 mem = 536880358 peak = 1139822592
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 291937, 10, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (149, 273, 893)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2381)
[M::mem_pestat] mean and std.dev: (519.79, 533.91)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3125)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 191, 292)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 610)
[M::mem_pestat] mean and std.dev: (221.88, 117.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 769)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (298, 383, 568)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1108)
[M::mem_pestat] mean and std.dev: (318.62, 167.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1378)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (227, 267, 533)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1145)
[M::mem_pestat] mean and std.dev: (347.47, 228.07)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1451)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 721906 sequences (100000281 bp) in 3.462 CPU sec, 3.615 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 291783, 21, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (181, 527, 1197)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3229)
[M::mem_pestat] mean and std.dev: (638.52, 623.36)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4245)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (133, 192, 292)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 610)
[M::mem_pestat] mean and std.dev: (222.00, 117.15)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 769)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (551, 1130, 1535)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3503)
[M::mem_pestat] mean and std.dev: (1053.70, 681.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4487)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 329, 947)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2429)
[M::mem_pestat] mean and std.dev: (468.06, 516.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3170)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 723098 reads in 217.888 CPU sec, 6.940 real sec
[M::process] read 722264 sequences (100000092 bp) in 3.075 CPU sec, 3.120 real sec...
[M::mem_process_seqs] Processed 723064 reads in 155.500 CPU sec, 4.925 real sec
sorting block 86, #reads = 1091651 mem = 536877175 peak = 1139822592
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 291173, 16, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (165, 278, 647)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1611)
[M::mem_pestat] mean and std.dev: (366.52, 355.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2093)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 193, 294)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 614)
[M::mem_pestat] mean and std.dev: (223.63, 118.33)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 774)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (72, 367, 2180)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6396)
[M::mem_pestat] mean and std.dev: (954.13, 1386.72)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8504)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (160, 272, 761)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1963)
[M::mem_pestat] mean and std.dev: (504.69, 480.29)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2564)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720998 sequences (100000157 bp) in 3.398 CPU sec, 3.545 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 290915, 23, 41)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (186, 376, 1332)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3624)
[M::mem_pestat] mean and std.dev: (610.45, 608.05)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4770)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 191, 290)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 602)
[M::mem_pestat] mean and std.dev: (220.94, 115.67)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 758)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (578, 638, 638)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (458, 758)
[M::mem_pestat] mean and std.dev: (619.77, 27.40)
[M::mem_pestat] low and high boundaries for proper pairs: (398, 818)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (251, 415, 1320)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3458)
[M::mem_pestat] mean and std.dev: (608.47, 577.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4527)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 721906 reads in 221.957 CPU sec, 7.100 real sec
[M::process] read 721036 sequences (100000183 bp) in 2.374 CPU sec, 2.381 real sec...
sorting block 87, #reads = 1089693 mem = 536879738 peak = 1139822592
[M::mem_process_seqs] Processed 722264 reads in 156.576 CPU sec, 4.999 real sec
sorting block 88, #reads = 1089657 mem = 536876663 peak = 1139822592
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 290938, 16, 29)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (188, 478, 1722)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4790)
[M::mem_pestat] mean and std.dev: (797.87, 800.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6324)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 193, 293)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 609)
[M::mem_pestat] mean and std.dev: (222.89, 116.40)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 767)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (283, 644, 1841)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4957)
[M::mem_pestat] mean and std.dev: (969.81, 897.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6515)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (177, 235, 671)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1659)
[M::mem_pestat] mean and std.dev: (379.46, 330.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2153)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720652 sequences (100000218 bp) in 3.194 CPU sec, 3.319 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 290556, 14, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 268, 389)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 821)
[M::mem_pestat] mean and std.dev: (236.69, 111.46)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1037)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 193, 294)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 612)
[M::mem_pestat] mean and std.dev: (223.26, 117.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 771)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (97, 254, 1005)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2821)
[M::mem_pestat] mean and std.dev: (385.83, 397.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3729)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (234, 589, 1023)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2601)
[M::mem_pestat] mean and std.dev: (676.56, 576.49)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3390)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720650 sequences (100000139 bp) in 2.542 CPU sec, 2.547 real sec...
[M::mem_process_seqs] Processed 720998 reads in 222.889 CPU sec, 7.101 real sec
[M::mem_process_seqs] Processed 721036 reads in 156.942 CPU sec, 5.043 real sec
sorting block 89, #reads = 1087575 mem = 536882750 peak = 1139822592
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 290515, 16, 32)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (210, 306, 412)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 816)
[M::mem_pestat] mean and std.dev: (306.38, 145.02)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1018)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 194, 294)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 612)
[M::mem_pestat] mean and std.dev: (223.63, 117.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 771)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (216, 412, 1305)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3483)
[M::mem_pestat] mean and std.dev: (679.06, 797.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4572)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (239, 463, 753)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1781)
[M::mem_pestat] mean and std.dev: (425.00, 314.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2295)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725140 sequences (100000058 bp) in 3.147 CPU sec, 3.237 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (30, 289992, 9, 40)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (134, 205, 350)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 782)
[M::mem_pestat] mean and std.dev: (258.96, 172.60)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 998)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 194, 296)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 618)
[M::mem_pestat] mean and std.dev: (224.50, 118.09)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 779)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (240, 330, 608)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1344)
[M::mem_pestat] mean and std.dev: (415.82, 271.14)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1712)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 735778 sequences (100000281 bp) in 2.436 CPU sec, 2.444 real sec...
[M::mem_process_seqs] Processed 720652 reads in 231.904 CPU sec, 7.442 real sec
[M::mem_process_seqs] Processed 720650 reads in 158.855 CPU sec, 5.052 real sec
sorting block 90, #reads = 1086794 mem = 536878905 peak = 1139822592
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 291858, 12, 45)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (199, 583, 805)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2017)
[M::mem_pestat] mean and std.dev: (500.36, 389.48)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2623)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 187, 282)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 582)
[M::mem_pestat] mean and std.dev: (215.13, 111.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 732)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (434, 544, 2269)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5939)
[M::mem_pestat] mean and std.dev: (1019.25, 862.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7774)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 261, 434)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 968)
[M::mem_pestat] mean and std.dev: (264.82, 143.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1235)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 733292 sequences (100000197 bp) in 3.158 CPU sec, 3.232 real sec...
[M::process] read 732130 sequences (100000035 bp) in 2.643 CPU sec, 2.645 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29, 295642, 13, 35)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (145, 206, 1183)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3259)
[M::mem_pestat] mean and std.dev: (557.62, 584.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4297)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (125, 173, 252)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 506)
[M::mem_pestat] mean and std.dev: (194.99, 94.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 633)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (80, 240, 2178)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6374)
[M::mem_pestat] mean and std.dev: (916.92, 1126.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 8472)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (245, 432, 890)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2180)
[M::mem_pestat] mean and std.dev: (623.72, 623.63)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3118)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 725140 reads in 250.160 CPU sec, 7.967 real sec
sorting block 91, #reads = 1084688 mem = 536883522 peak = 1139822592
[M::mem_process_seqs] Processed 735778 reads in 170.163 CPU sec, 5.428 real sec
sorting block 92, #reads = 1081812 mem = 536880014 peak = 1143746560
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 295402, 7, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (203, 344, 1440)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3914)
[M::mem_pestat] mean and std.dev: (500.48, 534.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5151)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (126, 177, 260)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 528)
[M::mem_pestat] mean and std.dev: (200.56, 100.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 662)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (162, 235, 408)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 900)
[M::mem_pestat] mean and std.dev: (257.04, 143.43)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1146)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 729444 sequences (100000092 bp) in 3.550 CPU sec, 3.675 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26, 294975, 8, 34)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 304, 942)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2408)
[M::mem_pestat] mean and std.dev: (577.24, 582.64)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3141)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (127, 178, 266)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 544)
[M::mem_pestat] mean and std.dev: (204.56, 103.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 683)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (167, 236, 330)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 656)
[M::mem_pestat] mean and std.dev: (214.93, 99.52)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 819)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 728038 sequences (100000125 bp) in 2.649 CPU sec, 2.645 real sec...
[M::mem_process_seqs] Processed 733292 reads in 232.611 CPU sec, 7.421 real sec
[M::mem_process_seqs] Processed 732130 reads in 168.097 CPU sec, 5.373 real sec
sorting block 93, #reads = 1091991 mem = 536883828 peak = 1143746560
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (17, 294246, 9, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (232, 408, 559)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1213)
[M::mem_pestat] mean and std.dev: (403.35, 254.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1540)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (129, 182, 273)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 561)
[M::mem_pestat] mean and std.dev: (209.21, 107.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 705)
[M::mem_pestat] skip orientation RF as there are not enough pairs
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (192, 289, 391)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 789)
[M::mem_pestat] mean and std.dev: (283.52, 171.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 988)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RR
[M::process] read 727046 sequences (100000255 bp) in 3.255 CPU sec, 3.350 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 293060, 21, 23)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (156, 185, 723)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1857)
[M::mem_pestat] mean and std.dev: (339.91, 328.80)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2424)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 183, 277)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 571)
[M::mem_pestat] mean and std.dev: (211.80, 109.44)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 718)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (174, 1049, 3849)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 11199)
[M::mem_pestat] mean and std.dev: (1835.24, 1947.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14874)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (253, 421, 749)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1741)
[M::mem_pestat] mean and std.dev: (402.26, 217.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2237)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726774 sequences (100000094 bp) in 2.430 CPU sec, 2.438 real sec...
[M::mem_process_seqs] Processed 729444 reads in 224.898 CPU sec, 7.163 real sec
sorting block 94, #reads = 1091729 mem = 536878703 peak = 1143746560
[M::mem_process_seqs] Processed 728038 reads in 156.567 CPU sec, 4.977 real sec
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25, 293760, 13, 36)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 228, 1461)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4037)
[M::mem_pestat] mean and std.dev: (751.92, 932.12)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5325)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 185, 281)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 581)
[M::mem_pestat] mean and std.dev: (214.46, 111.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 731)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (398, 1313, 1702)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4310)
[M::mem_pestat] mean and std.dev: (967.42, 578.00)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5614)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (244, 401, 869)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2119)
[M::mem_pestat] mean and std.dev: (403.48, 268.73)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2744)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
sorting block 95, #reads = 1090549 mem = 536883309 peak = 1143746560
[M::process] read 726860 sequences (100000072 bp) in 3.112 CPU sec, 3.210 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24, 292872, 20, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (157, 349, 1000)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2686)
[M::mem_pestat] mean and std.dev: (586.83, 642.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3529)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 185, 280)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 578)
[M::mem_pestat] mean and std.dev: (213.93, 111.31)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 727)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (158, 781, 4000)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 11684)
[M::mem_pestat] mean and std.dev: (1529.15, 1655.03)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 15526)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (130, 299, 675)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1765)
[M::mem_pestat] mean and std.dev: (424.82, 423.87)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2310)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 726260 sequences (100000092 bp) in 2.590 CPU sec, 2.582 real sec...
[M::mem_process_seqs] Processed 727046 reads in 225.100 CPU sec, 7.270 real sec
[M::mem_process_seqs] Processed 726774 reads in 160.259 CPU sec, 5.129 real sec
sorting block 96, #reads = 1090995 mem = 536879655 peak = 1143746560
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 292088, 20, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (143, 205, 1053)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2873)
[M::mem_pestat] mean and std.dev: (493.76, 584.85)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3783)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 185, 281)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 581)
[M::mem_pestat] mean and std.dev: (214.12, 111.61)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 731)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (277, 874, 1264)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3238)
[M::mem_pestat] mean and std.dev: (766.60, 533.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4225)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 462, 1273)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3385)
[M::mem_pestat] mean and std.dev: (852.76, 848.84)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4441)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 725262 sequences (100000114 bp) in 3.060 CPU sec, 3.163 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27, 292220, 19, 22)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (249, 589, 1599)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4299)
[M::mem_pestat] mean and std.dev: (1035.92, 1216.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5903)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (131, 186, 281)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 581)
[M::mem_pestat] mean and std.dev: (214.46, 111.23)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 731)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (506, 799, 1786)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4346)
[M::mem_pestat] mean and std.dev: (854.50, 733.47)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5626)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (201, 478, 676)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1626)
[M::mem_pestat] mean and std.dev: (407.84, 259.83)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2101)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 722792 sequences (100000247 bp) in 2.530 CPU sec, 2.535 real sec...
[M::mem_process_seqs] Processed 726860 reads in 220.645 CPU sec, 7.027 real sec
[M::mem_process_seqs] Processed 726260 reads in 152.874 CPU sec, 4.866 real sec
sorting block 97, #reads = 1088390 mem = 536878122 peak = 1143746560
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23, 292254, 15, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (209, 310, 2604)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7394)
[M::mem_pestat] mean and std.dev: (1468.52, 1943.41)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 9789)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (132, 187, 281)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 579)
[M::mem_pestat] mean and std.dev: (214.63, 110.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 728)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (124, 340, 1452)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4108)
[M::mem_pestat] mean and std.dev: (784.47, 884.75)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5436)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (326, 584, 898)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2042)
[M::mem_pestat] mean and std.dev: (594.85, 461.89)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2614)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 721754 sequences (100000239 bp) in 2.968 CPU sec, 3.044 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (22, 291232, 14, 43)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (238, 355, 1096)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2812)
[M::mem_pestat] mean and std.dev: (680.52, 727.68)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3670)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (134, 191, 288)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 596)
[M::mem_pestat] mean and std.dev: (220.02, 114.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 750)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (289, 564, 1460)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3802)
[M::mem_pestat] mean and std.dev: (758.64, 553.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4973)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (209, 482, 1690)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4652)
[M::mem_pestat] mean and std.dev: (712.85, 679.01)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6133)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 721000 sequences (100000013 bp) in 2.550 CPU sec, 2.548 real sec...
[M::mem_process_seqs] Processed 725262 reads in 216.963 CPU sec, 6.932 real sec
sorting block 98, #reads = 1089879 mem = 536880483 peak = 1143746560
[M::mem_process_seqs] Processed 722792 reads in 149.671 CPU sec, 4.903 real sec
sorting block 99, #reads = 1087929 mem = 536878513 peak = 1143746560
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 290804, 24, 50)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (178, 372, 625)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1519)
[M::mem_pestat] mean and std.dev: (438.13, 328.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1966)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 193, 293)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 609)
[M::mem_pestat] mean and std.dev: (222.73, 116.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 767)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (367, 577, 2196)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5854)
[M::mem_pestat] mean and std.dev: (938.18, 899.17)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7683)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (228, 351, 518)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1098)
[M::mem_pestat] mean and std.dev: (364.41, 200.20)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1388)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 720732 sequences (100000180 bp) in 3.027 CPU sec, 3.101 real sec...
[M::process] read 719790 sequences (100000124 bp) in 2.239 CPU sec, 2.242 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 290692, 12, 49)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (177, 253, 819)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2103)
[M::mem_pestat] mean and std.dev: (496.79, 519.21)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2745)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 194, 292)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 606)
[M::mem_pestat] mean and std.dev: (222.76, 115.71)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 763)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (374, 1456, 3457)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9623)
[M::mem_pestat] mean and std.dev: (1871.25, 2009.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 12706)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 274, 453)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 999)
[M::mem_pestat] mean and std.dev: (289.95, 163.99)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1272)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 721754 reads in 210.763 CPU sec, 6.837 real sec
[M::mem_process_seqs] Processed 721000 reads in 142.301 CPU sec, 4.529 real sec
sorting block 100, #reads = 1087505 mem = 536885211 peak = 1143746560
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38, 290840, 22, 25)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (162, 284, 469)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1083)
[M::mem_pestat] mean and std.dev: (282.75, 191.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1390)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (135, 193, 290)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 600)
[M::mem_pestat] mean and std.dev: (221.43, 113.98)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 755)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (283, 863, 1407)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3655)
[M::mem_pestat] mean and std.dev: (782.32, 641.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4779)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (166, 336, 2297)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6559)
[M::mem_pestat] mean and std.dev: (1514.92, 2238.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 10467)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 719370 sequences (100000271 bp) in 2.858 CPU sec, 2.895 real sec...
[M::process] read 719232 sequences (100000269 bp) in 2.410 CPU sec, 2.410 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 290409, 17, 38)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (279, 503, 1370)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3552)
[M::mem_pestat] mean and std.dev: (686.22, 648.11)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 4643)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 195, 294)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 610)
[M::mem_pestat] mean and std.dev: (223.74, 115.65)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 768)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (526, 2175, 8408)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 24172)
[M::mem_pestat] mean and std.dev: (3322.35, 3399.97)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 32054)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (217, 306, 832)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2062)
[M::mem_pestat] mean and std.dev: (448.18, 412.08)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2677)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 720732 reads in 203.307 CPU sec, 6.546 real sec
[M::mem_process_seqs] Processed 719790 reads in 140.384 CPU sec, 4.464 real sec
sorting block 101, #reads = 1089426 mem = 536879571 peak = 1143746560
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35, 289905, 19, 30)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (260, 352, 1190)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3050)
[M::mem_pestat] mean and std.dev: (591.87, 706.18)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3980)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 196, 297)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 619)
[M::mem_pestat] mean and std.dev: (225.83, 117.92)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 780)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (474, 713, 1937)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4863)
[M::mem_pestat] mean and std.dev: (918.28, 720.38)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 6326)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (206, 369, 686)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1646)
[M::mem_pestat] mean and std.dev: (432.19, 342.19)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2126)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::process] read 718524 sequences (100000044 bp) in 2.963 CPU sec, 3.027 real sec...
[M::process] read 525864 sequences (73074501 bp) in 1.980 CPU sec, 1.977 real sec...
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 290392, 23, 44)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (141, 417, 671)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1731)
[M::mem_pestat] mean and std.dev: (356.64, 226.30)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 2261)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 196, 299)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 625)
[M::mem_pestat] mean and std.dev: (226.76, 119.26)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 788)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (114, 556, 3767)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 11073)
[M::mem_pestat] mean and std.dev: (1906.17, 2521.45)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 14726)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (239, 403, 1014)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2564)
[M::mem_pestat] mean and std.dev: (643.00, 565.25)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3339)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 719370 reads in 200.247 CPU sec, 6.522 real sec
sorting block 102, #reads = 1087535 mem = 536884291 peak = 1143746560
[M::mem_process_seqs] Processed 719232 reads in 133.403 CPU sec, 4.257 real sec
sorting block 103, #reads = 1089227 mem = 536880552 peak = 1143746560
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 290081, 21, 33)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (191, 571, 1990)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5588)
[M::mem_pestat] mean and std.dev: (1046.67, 1170.81)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 7387)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (137, 198, 303)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 635)
[M::mem_pestat] mean and std.dev: (229.22, 121.53)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 801)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (63, 449, 1439)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4191)
[M::mem_pestat] mean and std.dev: (519.17, 569.24)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 5567)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (171, 232, 379)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 795)
[M::mem_pestat] mean and std.dev: (251.50, 116.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1003)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (13, 211924, 11, 26)
[M::mem_pestat] analyzing insert size distribution for orientation FF...
[M::mem_pestat] (25, 50, 75) percentile: (173, 205, 1108)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2978)
[M::mem_pestat] mean and std.dev: (615.00, 813.16)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3913)
[M::mem_pestat] analyzing insert size distribution for orientation FR...
[M::mem_pestat] (25, 50, 75) percentile: (136, 196, 299)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 625)
[M::mem_pestat] mean and std.dev: (226.72, 119.74)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 788)
[M::mem_pestat] analyzing insert size distribution for orientation RF...
[M::mem_pestat] (25, 50, 75) percentile: (291, 522, 1005)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2433)
[M::mem_pestat] mean and std.dev: (529.50, 391.39)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 3147)
[M::mem_pestat] analyzing insert size distribution for orientation RR...
[M::mem_pestat] (25, 50, 75) percentile: (180, 366, 557)
[M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1311)
[M::mem_pestat] mean and std.dev: (376.28, 189.13)
[M::mem_pestat] low and high boundaries for proper pairs: (1, 1688)
[M::mem_pestat] skip orientation FF
[M::mem_pestat] skip orientation RF
[M::mem_pestat] skip orientation RR
[M::mem_process_seqs] Processed 718524 reads in 183.626 CPU sec, 5.970 real sec
[M::mem_process_seqs] Processed 525864 reads in 113.596 CPU sec, 3.673 real sec
sorting block 104, #reads = 1088966 mem = 536877860 peak = 1143746560
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000c06f2
  features: bfebfbff 7ffefbff
  extended: f3bfb7ef fb417ffe
  amd bits: 2c100800 00000121
     brand: INTEL(R) XEON(R) PLATINUM 8559C
threads: 31
algo: bwa-mem
license: sentieon:klib=31
reads: 113945616
overall: 70187732992 mem 20645.129 user 648.717 sys 722.691 real
[main] Version: 0.7.17-r1188
[main] CMD: /opt/conda/share/sentieon-202308.03-3/libexec/bwa mem -K 100000000 -Y -R @RG\tID:A23MHWWLT4.1136_8DV-T1-TDNA-1_A23MHWWLT4_1.L004\tPU:L004\tSM:1136_8DV-T1-TDNA-1_A23MHWWLT4_1\tLB:1136_8DV-T1-TDNA-1_A23MHWWLT4_1\tDS:s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta\tPL:ILLUMINA -t 31 ./BWAIndex/Homo_sapiens_assembly38.fasta.64 1136_8DV-T1-TDNA-1_A23MHWWLT4_1_R1.fastq.gz 1136_8DV-T1-TDNA-1_A23MHWWLT4_1_R2.fastq.gz
[main] Real time: 722.730 sec; CPU: 21293.849 sec
sorting block 105, #reads = 243594 mem = 120980611 peak = 1143746560
uniq header count 1
merging 106 blocks
sw version: sentieon-genomics-202308.03
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000c06f2
  features: bfebfbff 7ffefbff
  extended: f3bfb7ef fb417ffe
  amd bits: 2c100800 00000121
     brand: INTEL(R) XEON(R) PLATINUM 8559C
threads: 31 max 192
algo: util-sort
license: sentieon:util=1
output file size: 6312192920
output reads: 114785313
bam_mem_sort: 106 calls 74.433 user 2.753 sys 77.736 real
bam_write: 106 calls 50.888 user 4.695 sys 73.084 real
execute: 1 calls 38.305 user 1.974 sys 770.197 real
merge_files: 1 calls 38.272 user 1.928 sys 47.294 real
parse_chunk: 1684 calls 97.567 user 26.838 sys 130.300 real
read_chunk: 4565 calls 61.134 user 39.014 sys 645.212 real
sort_block: 1 calls 41.730 user 38.592 sys 620.671 real
write_chunk: 2879 calls 37.909 user 1.592 sys 46.156 real
overall: 3392569344 mem 1888.865 user 98.012 sys 770.226 real
ls: cannot access '*.cram': No such file or directory