Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/47/caac6e06ebf0151d8243f7cc964eed/Sig_18_tissue.cns
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/0c/5575d4a8b69c7752fdd404134cb448/.command.sh
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/0c/5575d4a8b69c7752fdd404134cb448/.command.run
==> STAGING COMPLETE (3 inputs)

Matplotlib created a temporary config/cache directory at /tmp/matplotlib-avu_qwp9 because the default path (/.config/matplotlib) is not a writable directory; it is highly recommended to set the MPLCONFIGDIR environment variable to a writable directory, in particular to speed up the import of Matplotlib and to better support multiprocessing.
Fontconfig error: No writable cache directories
Calling copy number with thresholds: -1.1 => 0, -0.25 => 1, 0.2 => 2, 0.7 => 3
Wrote Sig_18_tissue.somatic.call.cns with 6 regions
Matplotlib created a temporary config/cache directory at /tmp/matplotlib-xeubwuef because the default path (/.config/matplotlib) is not a writable directory; it is highly recommended to set the MPLCONFIGDIR environment variable to a writable directory, in particular to speed up the import of Matplotlib and to better support multiprocessing.
Fontconfig error: No writable cache directories