File Info

Filename
multiqc_data/multiqc_data.json
Full Path
s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/6a/e5f9e499e2398646b31d9e6edf05fc/multiqc_data/multiqc_data.json
Size
2.2 MB
Attempt
{
  "report_multiqc_command": "/opt/conda/bin/multiqc --force --config multiqc_config.yml .",
  "report_data_sources": {
    "Samtools Flagstat": {
      "stats": {
        "HCC1395_BL": "/tmp/nxf.uMOsqH3Syc/4/HCC1395_BL.stats",
        "HCC1395_tumor": "/tmp/nxf.uMOsqH3Syc/3/HCC1395_tumor.stats",
        "Sig_18_Blood": "/tmp/nxf.uMOsqH3Syc/5/Sig_18_Blood.stats",
        "Sig_18_tissue": "/tmp/nxf.uMOsqH3Syc/10/Sig_18_tissue.stats"
      }
    },
    "Mosdepth": {
      "genome_results": {
        "HCC1395_BL": "/tmp/nxf.uMOsqH3Syc/13/HCC1395_BL.mosdepth.region.dist.txt",
        "HCC1395_tumor": "/tmp/nxf.uMOsqH3Syc/9/HCC1395_tumor.mosdepth.region.dist.txt",
        "Sig_18_Blood": "/tmp/nxf.uMOsqH3Syc/11/Sig_18_Blood.mosdepth.region.dist.txt",
        "Sig_18_tissue": "/tmp/nxf.uMOsqH3Syc/6/Sig_18_tissue.mosdepth.region.dist.txt"
      }
    },
    "Bcftools": {
      "stats": {
        "HCC1395_BL": "/tmp/nxf.uMOsqH3Syc/40/HCC1395_BL.bcftools_stats.txt",
        "HCC1395_BL.deconflicted_germline": "/tmp/nxf.uMOsqH3Syc/48/HCC1395_BL.deconflicted_germline.bcftools_stats.txt",
        "HCC1395_tumor_vs_HCC1395_BL.manta.diploid_sv": "/tmp/nxf.uMOsqH3Syc/37/HCC1395_tumor_vs_HCC1395_BL.manta.diploid_sv.bcftools_stats.txt",
        "HCC1395_tumor_vs_HCC1395_BL.manta.somatic_sv": "/tmp/nxf.uMOsqH3Syc/38/HCC1395_tumor_vs_HCC1395_BL.manta.somatic_sv.bcftools_stats.txt",
        "HCC1395_tumor_vs_HCC1395_BL.strelka.somatic_indels": "/tmp/nxf.uMOsqH3Syc/43/HCC1395_tumor_vs_HCC1395_BL.strelka.somatic_indels.bcftools_stats.txt",
        "HCC1395_tumor_vs_HCC1395_BL.strelka.somatic_snvs": "/tmp/nxf.uMOsqH3Syc/44/HCC1395_tumor_vs_HCC1395_BL.strelka.somatic_snvs.bcftools_stats.txt",
        "Sig_18_Blood": "/tmp/nxf.uMOsqH3Syc/39/Sig_18_Blood.bcftools_stats.txt",
        "Sig_18_Blood.deconflicted_germline": "/tmp/nxf.uMOsqH3Syc/47/Sig_18_Blood.deconflicted_germline.bcftools_stats.txt",
        "custom_Sig_18_tumor_normal.manta.diploid_sv": "/tmp/nxf.uMOsqH3Syc/41/custom_Sig_18_tumor_normal.manta.diploid_sv.bcftools_stats.txt",
        "custom_Sig_18_tumor_normal.manta.somatic_sv": "/tmp/nxf.uMOsqH3Syc/42/custom_Sig_18_tumor_normal.manta.somatic_sv.bcftools_stats.txt",
        "custom_Sig_18_tumor_normal.strelka.somatic_indels": "/tmp/nxf.uMOsqH3Syc/45/custom_Sig_18_tumor_normal.strelka.somatic_indels.bcftools_stats.txt",
        "custom_Sig_18_tumor_normal.strelka.somatic_snvs": "/tmp/nxf.uMOsqH3Syc/46/custom_Sig_18_tumor_normal.strelka.somatic_snvs.bcftools_stats.txt"
      }
    },
    "Vcftools": {
      "all_sections": {
        "TsTv by counts": "/tmp/nxf.uMOsqH3Syc/57/custom_Sig_18_tumor_normal.strelka.somatic_snvs.TsTv.count",
        "TsTv by quality": "/tmp/nxf.uMOsqH3Syc/69/custom_Sig_18_tumor_normal.strelka.somatic_snvs.TsTv.qual"
      }
    },
    "SNPeff": {
      "all_sections": {
        "HCC1395_BL.deconflicted_germline_custom.ann_snpEff": "/tmp/nxf.uMOsqH3Syc/88/HCC1395_BL.deconflicted_germline_custom.ann_snpEff.csv",
        "HCC1395_BL_custom.ann_snpEff": "/tmp/nxf.uMOsqH3Syc/19/HCC1395_BL_custom.ann_snpEff.csv",
        "HCC1395_tumor_vs_HCC1395_BL.manta.diploid_sv_custom.ann_snpEff": "/tmp/nxf.uMOsqH3Syc/17/HCC1395_tumor_vs_HCC1395_BL.manta.diploid_sv_custom.ann_snpEff.csv",
        "HCC1395_tumor_vs_HCC1395_BL.manta.somatic_sv_custom.ann_snpEff": "/tmp/nxf.uMOsqH3Syc/18/HCC1395_tumor_vs_HCC1395_BL.manta.somatic_sv_custom.ann_snpEff.csv",
        "HCC1395_tumor_vs_HCC1395_BL.strelka.somatic_indels_custom.ann_snpEff": "/tmp/nxf.uMOsqH3Syc/25/HCC1395_tumor_vs_HCC1395_BL.strelka.somatic_indels_custom.ann_snpEff.csv",
        "HCC1395_tumor_vs_HCC1395_BL.strelka.somatic_snvs_custom.ann_snpEff": "/tmp/nxf.uMOsqH3Syc/27/HCC1395_tumor_vs_HCC1395_BL.strelka.somatic_snvs_custom.ann_snpEff.csv",
        "Sig_18_Blood.deconflicted_germline_custom.ann_snpEff": "/tmp/nxf.uMOsqH3Syc/87/Sig_18_Blood.deconflicted_germline_custom.ann_snpEff.csv",
        "Sig_18_Blood_custom.ann_snpEff": "/tmp/nxf.uMOsqH3Syc/21/Sig_18_Blood_custom.ann_snpEff.csv",
        "custom_Sig_18_tumor_normal.manta.diploid_sv_custom.ann_snpEff": "/tmp/nxf.uMOsqH3Syc/20/custom_Sig_18_tumor_normal.manta.diploid_sv_custom.ann_snpEff.csv",
        "custom_Sig_18_tumor_normal.manta.somatic_sv_custom.ann_snpEff": "/tmp/nxf.uMOsqH3Syc/22/custom_Sig_18_tumor_normal.manta.somatic_sv_custom.ann_snpEff.csv",
        "custom_Sig_18_tumor_normal.strelka.somatic_indels_custom.ann_snpEff": "/tmp/nxf.uMOsqH3Syc/34/custom_Sig_18_tumor_normal.strelka.somatic_indels_custom.ann_snpEff.csv",
        "custom_Sig_18_tumor_normal.strelka.somatic_snvs_custom.ann_snpEff": "/tmp/nxf.uMOsqH3Syc/33/custom_Sig_18_tumor_normal.strelka.somatic_snvs_custom.ann_snpEff.csv"
      }
    },
    "VEP": {
      "all_sections": {
        "HCC1395_BL.deconflicted_germline_custom.ann_snpEff_VEP.ann": "/tmp/nxf.uMOsqH3Syc/90/HCC1395_BL.deconflicted_germline_custom.ann_snpEff_VEP.ann.summary.html",
        "HCC1395_BL_custom.ann_snpEff_VEP.ann": "/tmp/nxf.uMOsqH3Syc/28/HCC1395_BL_custom.ann_snpEff_VEP.ann.summary.html",
        "HCC1395_tumor_vs_HCC1395_BL.manta.diploid_sv_custom.ann_snpEff_VEP.ann": "/tmp/nxf.uMOsqH3Syc/23/HCC1395_tumor_vs_HCC1395_BL.manta.diploid_sv_custom.ann_snpEff_VEP.ann.summary.html",
        "HCC1395_tumor_vs_HCC1395_BL.manta.somatic_sv_custom.ann_snpEff_VEP.ann": "/tmp/nxf.uMOsqH3Syc/24/HCC1395_tumor_vs_HCC1395_BL.manta.somatic_sv_custom.ann_snpEff_VEP.ann.summary.html",
        "HCC1395_tumor_vs_HCC1395_BL.strelka.somatic_indels_custom.ann_snpEff_VEP.ann": "/tmp/nxf.uMOsqH3Syc/32/HCC1395_tumor_vs_HCC1395_BL.strelka.somatic_indels_custom.ann_snpEff_VEP.ann.summary.html",
        "HCC1395_tumor_vs_HCC1395_BL.strelka.somatic_snvs_custom.ann_snpEff_VEP.ann": "/tmp/nxf.uMOsqH3Syc/31/HCC1395_tumor_vs_HCC1395_BL.strelka.somatic_snvs_custom.ann_snpEff_VEP.ann.summary.html",
        "Sig_18_Blood.deconflicted_germline_custom.ann_snpEff_VEP.ann": "/tmp/nxf.uMOsqH3Syc/89/Sig_18_Blood.deconflicted_germline_custom.ann_snpEff_VEP.ann.summary.html",
        "Sig_18_Blood_custom.ann_snpEff_VEP.ann": "/tmp/nxf.uMOsqH3Syc/30/Sig_18_Blood_custom.ann_snpEff_VEP.ann.summary.html",
        "custom_Sig_18_tumor_normal.manta.diploid_sv_custom.ann_snpEff_VEP.ann": "/tmp/nxf.uMOsqH3Syc/29/custom_Sig_18_tumor_normal.manta.diploid_sv_custom.ann_snpEff_VEP.ann.summary.html",
        "custom_Sig_18_tumor_normal.manta.somatic_sv_custom.ann_snpEff_VEP.ann": "/tmp/nxf.uMOsqH3Syc/26/custom_Sig_18_tumor_normal.manta.somatic_sv_custom.ann_snpEff_VEP.ann.summary.html",
        "custom_Sig_18_tumor_normal.strelka.somatic_indels_custom.ann_snpEff_VEP.ann": "/tmp/nxf.uMOsqH3Syc/36/custom_Sig_18_tumor_normal.strelka.somatic_indels_custom.ann_snpEff_VEP.ann.summary.html",
        "custom_Sig_18_tumor_normal.strelka.somatic_snvs_custom.ann_snpEff_VEP.ann": "/tmp/nxf.uMOsqH3Syc/35/custom_Sig_18_tumor_normal.strelka.somatic_snvs_custom.ann_snpEff_VEP.ann.summary.html"
      }
    }
  },
  "report_general_stats_data": {
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      "HCC1395_BL.deconflicted_germline": {
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      "HCC1395_tumor_vs_HCC1395_BL.manta.diploid_sv": {
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        "splice_acceptor_variant": 1.0,
        "splice_acceptor_variant_percent": 0.21322,
        "splice_donor_variant": 1.0,
        "splice_donor_variant_percent": 0.21322,
        "splice_region_variant": 11.0,
        "splice_region_variant_percent": 2.345416,
        "stop_gained": 1.0,
        "stop_gained_percent": 0.21322,
        "stop_lost": 1.0,
        "stop_lost_percent": 0.21322,
        "synonymous_variant": 35.0,
        "synonymous_variant_percent": 7.462687,
        "upstream_gene_variant": 45.0,
        "upstream_gene_variant_percent": 9.594883,
        "DOWNSTREAM": 34.0,
        "DOWNSTREAM_percent": 7.45614,
        "EXON": 105.0,
        "EXON_percent": 23.026316,
        "INTERGENIC": 2.0,
        "INTERGENIC_percent": 0.438596,
        "INTRON": 219.0,
        "INTRON_percent": 48.026316,
        "SPLICE_SITE_ACCEPTOR": 1.0,
        "SPLICE_SITE_ACCEPTOR_percent": 0.219298,
        "SPLICE_SITE_DONOR": 1.0,
        "SPLICE_SITE_DONOR_percent": 0.219298,
        "SPLICE_SITE_REGION": 11.0,
        "SPLICE_SITE_REGION_percent": 2.412281,
        "TRANSCRIPT": 23.0,
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        "UPSTREAM": 45.0,
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        "UTR_3_PRIME_percent": 2.192982,
        "UTR_5_PRIME": 5.0,
        "UTR_5_PRIME_percent": 1.096491,
        "Transitions": 310.0,
        "Transversions": 290.0,
        "Ts_Tv_ratio": 1.068966,
        "Het": 0.0,
        "Hom": 0.0,
        "Missing": 300.0
      },
      "Sig_18_Blood.deconflicted_germline_custom.ann_snpEff": {
        "Number_of_variants_before_filter": 395.0,
        "Number_of_known_variants (i.e. non-empty ID)": 391.0,
        "Number_of_known_variants (i.e. non-empty ID)_percent": 98.987342,
        "Number_of_effects": 605.0,
        "Genome_total_length": 63147197748.0,
        "Genome_effective_length": 46709983.0,
        "Change_rate": 118253.0,
        "HIGH": 9.0,
        "HIGH_percent": 1.487603,
        "LOW": 139.0,
        "LOW_percent": 22.975207,
        "MODERATE": 156.0,
        "MODERATE_percent": 25.785124,
        "MODIFIER": 301.0,
        "MODIFIER_percent": 49.752066,
        "MISSENSE": 149.0,
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        "NONSENSE": 2.0,
        "NONSENSE_percent": 0.701754,
        "SILENT": 134.0,
        "SILENT_percent": 47.017544,
        "Missense_Silent_ratio": 1.11194,
        "3_prime_UTR_variant": 7.0,
        "3_prime_UTR_variant_percent": 1.145663,
        "5_prime_UTR_premature_start_codon_gain_variant": 1.0,
        "5_prime_UTR_premature_start_codon_gain_variant_percent": 0.163666,
        "5_prime_UTR_variant": 7.0,
        "5_prime_UTR_variant_percent": 1.145663,
        "conservative_inframe_insertion": 1.0,
        "conservative_inframe_insertion_percent": 0.163666,
        "disruptive_inframe_deletion": 3.0,
        "disruptive_inframe_deletion_percent": 0.490998,
        "disruptive_inframe_insertion": 3.0,
        "disruptive_inframe_insertion_percent": 0.490998,
        "downstream_gene_variant": 47.0,
        "downstream_gene_variant_percent": 7.692308,
        "frameshift_variant": 7.0,
        "frameshift_variant_percent": 1.145663,
        "intragenic_variant": 31.0,
        "intragenic_variant_percent": 5.07365,
        "intron_variant": 142.0,
        "intron_variant_percent": 23.240589,
        "missense_variant": 149.0,
        "missense_variant_percent": 24.386252,
        "non_coding_transcript_exon_variant": 24.0,
        "non_coding_transcript_exon_variant_percent": 3.927987,
        "splice_region_variant": 8.0,
        "splice_region_variant_percent": 1.309329,
        "stop_gained": 2.0,
        "stop_gained_percent": 0.327332,
        "synonymous_variant": 134.0,
        "synonymous_variant_percent": 21.93126,
        "upstream_gene_variant": 45.0,
        "upstream_gene_variant_percent": 7.364975,
        "DOWNSTREAM": 47.0,
        "DOWNSTREAM_percent": 7.768595,
        "EXON": 319.0,
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        "INTRON": 142.0,
        "INTRON_percent": 23.471074,
        "SPLICE_SITE_REGION": 6.0,
        "SPLICE_SITE_REGION_percent": 0.991736,
        "TRANSCRIPT": 31.0,
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        "UPSTREAM": 45.0,
        "UPSTREAM_percent": 7.438017,
        "UTR_3_PRIME": 7.0,
        "UTR_3_PRIME_percent": 1.157025,
        "UTR_5_PRIME": 8.0,
        "UTR_5_PRIME_percent": 1.322314,
        "Transitions": 381.0,
        "Transversions": 133.0,
        "Ts_Tv_ratio": 2.864662,
        "Het": 241.0,
        "Hom": 154.0,
        "Missing": 0.0
      },
      "Sig_18_Blood_custom.ann_snpEff": {
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        "Number_of_known_variants (i.e. non-empty ID)": 0.0,
        "Number_of_known_variants (i.e. non-empty ID)_percent": 0.0,
        "Number_of_effects": 16.0,
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        "LOW": 1.0,
        "LOW_percent": 6.25,
        "MODIFIER": 5.0,
        "MODIFIER_percent": 31.25,
        "Missense_Silent_ratio": 0.0,
        "bidirectional_gene_fusion": 1.0,
        "bidirectional_gene_fusion_percent": 5.555556,
        "conservative_inframe_deletion": 1.0,
        "conservative_inframe_deletion_percent": 5.555556,
        "downstream_gene_variant": 1.0,
        "downstream_gene_variant_percent": 5.555556,
        "exon_loss_variant": 7.0,
        "exon_loss_variant_percent": 38.888889,
        "gene_fusion": 1.0,
        "gene_fusion_percent": 5.555556,
        "intron_variant": 3.0,
        "intron_variant_percent": 16.666667,
        "non_coding_transcript_exon_variant": 1.0,
        "non_coding_transcript_exon_variant_percent": 5.555556,
        "splice_region_variant": 1.0,
        "splice_region_variant_percent": 5.555556,
        "start_lost": 1.0,
        "start_lost_percent": 5.555556,
        "upstream_gene_variant": 1.0,
        "upstream_gene_variant_percent": 5.555556,
        "DOWNSTREAM": 1.0,
        "DOWNSTREAM_percent": 6.25,
        "EXON": 8.0,
        "EXON_percent": 50.0,
        "GENE": 2.0,
        "GENE_percent": 12.5,
        "INTRON": 3.0,
        "INTRON_percent": 18.75,
        "SPLICE_SITE_REGION": 1.0,
        "SPLICE_SITE_REGION_percent": 6.25,
        "UPSTREAM": 1.0,
        "UPSTREAM_percent": 6.25,
        "Transitions": 0.0,
        "Transversions": 0.0,
        "Ts_Tv_ratio": 0.0,
        "Het": 2.0,
        "Hom": 0.0,
        "Missing": 0.0
      },
      "custom_Sig_18_tumor_normal.manta.diploid_sv_custom.ann_snpEff": {
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        "Number_of_known_variants (i.e. non-empty ID)": 4.0,
        "Number_of_known_variants (i.e. non-empty ID)_percent": 66.666667,
        "Number_of_effects": 19.0,
        "Genome_total_length": 63147197748.0,
        "Genome_effective_length": 46709983.0,
        "Change_rate": 7784997.0,
        "HIGH": 12.0,
        "HIGH_percent": 63.157895,
        "MODERATE": 1.0,
        "MODERATE_percent": 5.263158,
        "MODIFIER": 6.0,
        "MODIFIER_percent": 31.578947,
        "Missense_Silent_ratio": 0.0,
        "bidirectional_gene_fusion": 12.0,
        "bidirectional_gene_fusion_percent": 63.157895,
        "conservative_inframe_deletion": 1.0,
        "conservative_inframe_deletion_percent": 5.263158,
        "downstream_gene_variant": 1.0,
        "downstream_gene_variant_percent": 5.263158,
        "intragenic_variant": 1.0,
        "intragenic_variant_percent": 5.263158,
        "intron_variant": 2.0,
        "intron_variant_percent": 10.526316,
        "upstream_gene_variant": 2.0,
        "upstream_gene_variant_percent": 10.526316,
        "DOWNSTREAM": 1.0,
        "DOWNSTREAM_percent": 5.263158,
        "EXON": 1.0,
        "EXON_percent": 5.263158,
        "GENE": 12.0,
        "GENE_percent": 63.157895,
        "INTRON": 2.0,
        "INTRON_percent": 10.526316,
        "TRANSCRIPT": 1.0,
        "TRANSCRIPT_percent": 5.263158,
        "UPSTREAM": 2.0,
        "UPSTREAM_percent": 10.526316,
        "Transitions": 0.0,
        "Transversions": 0.0,
        "Ts_Tv_ratio": 0.0,
        "Het": 5.0,
        "Hom": 1.0,
        "Missing": 0.0
      },
      "custom_Sig_18_tumor_normal.manta.somatic_sv_custom.ann_snpEff": {
        "Number_of_variants_before_filter": 0.0,
        "Number_of_known_variants (i.e. non-empty ID)": 0.0,
        "Number_of_known_variants (i.e. non-empty ID)_percent": 0.0,
        "Number_of_effects": 0.0,
        "Genome_total_length": 63147197748.0,
        "Genome_effective_length": 0.0,
        "Change_rate": 0.0,
        "Missense_Silent_ratio": 0.0,
        "Transitions": 0.0,
        "Transversions": 0.0,
        "Ts_Tv_ratio": 0.0
      },
      "custom_Sig_18_tumor_normal.strelka.somatic_indels_custom.ann_snpEff": {
        "Number_of_variants_before_filter": 88.0,
        "Number_of_known_variants (i.e. non-empty ID)": 0.0,
        "Number_of_known_variants (i.e. non-empty ID)_percent": 0.0,
        "Number_of_effects": 129.0,
        "Genome_total_length": 63147197748.0,
        "Genome_effective_length": 46709983.0,
        "Change_rate": 530795.0,
        "HIGH": 8.0,
        "HIGH_percent": 6.20155,
        "LOW": 9.0,
        "LOW_percent": 6.976744,
        "MODERATE": 8.0,
        "MODERATE_percent": 6.20155,
        "MODIFIER": 104.0,
        "MODIFIER_percent": 80.620155,
        "Missense_Silent_ratio": 0.0,
        "3_prime_UTR_variant": 2.0,
        "3_prime_UTR_variant_percent": 1.449275,
        "5_prime_UTR_variant": 1.0,
        "5_prime_UTR_variant_percent": 0.724638,
        "conservative_inframe_deletion": 1.0,
        "conservative_inframe_deletion_percent": 0.724638,
        "disruptive_inframe_deletion": 3.0,
        "disruptive_inframe_deletion_percent": 2.173913,
        "disruptive_inframe_insertion": 4.0,
        "disruptive_inframe_insertion_percent": 2.898551,
        "downstream_gene_variant": 13.0,
        "downstream_gene_variant_percent": 9.42029,
        "frameshift_variant": 8.0,
        "frameshift_variant_percent": 5.797101,
        "intergenic_region": 1.0,
        "intergenic_region_percent": 0.724638,
        "intragenic_variant": 5.0,
        "intragenic_variant_percent": 3.623188,
        "intron_variant": 75.0,
        "intron_variant_percent": 54.347826,
        "non_coding_transcript_exon_variant": 3.0,
        "non_coding_transcript_exon_variant_percent": 2.173913,
        "splice_region_variant": 9.0,
        "splice_region_variant_percent": 6.521739,
        "upstream_gene_variant": 13.0,
        "upstream_gene_variant_percent": 9.42029,
        "DOWNSTREAM": 13.0,
        "DOWNSTREAM_percent": 10.077519,
        "EXON": 19.0,
        "EXON_percent": 14.728682,
        "INTERGENIC": 1.0,
        "INTERGENIC_percent": 0.775194,
        "INTRON": 66.0,
        "INTRON_percent": 51.162791,
        "SPLICE_SITE_REGION": 9.0,
        "SPLICE_SITE_REGION_percent": 6.976744,
        "TRANSCRIPT": 5.0,
        "TRANSCRIPT_percent": 3.875969,
        "UPSTREAM": 13.0,
        "UPSTREAM_percent": 10.077519,
        "UTR_3_PRIME": 2.0,
        "UTR_3_PRIME_percent": 1.550388,
        "UTR_5_PRIME": 1.0,
        "UTR_5_PRIME_percent": 0.775194,
        "Transitions": 0.0,
        "Transversions": 0.0,
        "Ts_Tv_ratio": 0.0,
        "Het": 0.0,
        "Hom": 0.0,
        "Missing": 88.0
      },
      "custom_Sig_18_tumor_normal.strelka.somatic_snvs_custom.ann_snpEff": {
        "Number_of_variants_before_filter": 237.0,
        "Number_of_known_variants (i.e. non-empty ID)": 0.0,
        "Number_of_known_variants (i.e. non-empty ID)_percent": 0.0,
        "Number_of_effects": 381.0,
        "Genome_total_length": 63147197748.0,
        "Genome_effective_length": 46709983.0,
        "Change_rate": 197088.0,
        "HIGH": 2.0,
        "HIGH_percent": 0.524934,
        "LOW": 34.0,
        "LOW_percent": 8.923885,
        "MODERATE": 52.0,
        "MODERATE_percent": 13.648294,
        "MODIFIER": 293.0,
        "MODIFIER_percent": 76.902887,
        "MISSENSE": 52.0,
        "MISSENSE_percent": 66.666667,
        "NONSENSE": 2.0,
        "NONSENSE_percent": 2.564103,
        "SILENT": 24.0,
        "SILENT_percent": 30.769231,
        "Missense_Silent_ratio": 2.166667,
        "3_prime_UTR_variant": 9.0,
        "3_prime_UTR_variant_percent": 2.290076,
        "5_prime_UTR_premature_start_codon_gain_variant": 1.0,
        "5_prime_UTR_premature_start_codon_gain_variant_percent": 0.254453,
        "5_prime_UTR_variant": 4.0,
        "5_prime_UTR_variant_percent": 1.017812,
        "downstream_gene_variant": 33.0,
        "downstream_gene_variant_percent": 8.396947,
        "intergenic_region": 1.0,
        "intergenic_region_percent": 0.254453,
        "intragenic_variant": 22.0,
        "intragenic_variant_percent": 5.597964,
        "intron_variant": 189.0,
        "intron_variant_percent": 48.091603,
        "missense_variant": 52.0,
        "missense_variant_percent": 13.231552,
        "non_coding_transcript_exon_variant": 5.0,
        "non_coding_transcript_exon_variant_percent": 1.272265,
        "splice_region_variant": 12.0,
        "splice_region_variant_percent": 3.053435,
        "stop_gained": 2.0,
        "stop_gained_percent": 0.508906,
        "synonymous_variant": 24.0,
        "synonymous_variant_percent": 6.10687,
        "upstream_gene_variant": 39.0,
        "upstream_gene_variant_percent": 9.923664,
        "DOWNSTREAM": 33.0,
        "DOWNSTREAM_percent": 8.661417,
        "EXON": 83.0,
        "EXON_percent": 21.784777,
        "INTERGENIC": 1.0,
        "INTERGENIC_percent": 0.262467,
        "INTRON": 180.0,
        "INTRON_percent": 47.244094,
        "SPLICE_SITE_REGION": 9.0,
        "SPLICE_SITE_REGION_percent": 2.362205,
        "TRANSCRIPT": 22.0,
        "TRANSCRIPT_percent": 5.774278,
        "UPSTREAM": 39.0,
        "UPSTREAM_percent": 10.23622,
        "UTR_3_PRIME": 9.0,
        "UTR_3_PRIME_percent": 2.362205,
        "UTR_5_PRIME": 5.0,
        "UTR_5_PRIME_percent": 1.312336,
        "Transitions": 262.0,
        "Transversions": 212.0,
        "Ts_Tv_ratio": 1.235849,
        "Het": 0.0,
        "Hom": 0.0,
        "Missing": 237.0
      }
    }
  },
  "report_general_stats_headers": {
    "samtools": {
      "error_rate": {
        "title": "Error rate",
        "description": "Error rate: mismatches (NM) / bases mapped (CIGAR)",
        "min": 0,
        "max": 100,
        "suffix": "%",
        "scale": "OrRd",
        "format": "{:,.2f}",
        "modify": null,
        "hidden": false,
        "namespace": "Samtools Flagstat: stats",
        "clean_rid": "samtools_flagstat_stats-error_rate",
        "rid": "samtools_flagstat_stats-error_rate",
        "placement": 1000
      },
      "non-primary_alignments": {
        "title": "Non-primary",
        "description": "Non-primary alignments (millions)",
        "scale": "PuBu",
        "shared_key": "read_count",
        "hidden": false,
        "namespace": "Samtools Flagstat: stats",
        "clean_rid": "samtools_flagstat_stats-non_primary_alignments",
        "rid": "samtools_flagstat_stats-non_primary_alignments",
        "modify": null,
        "min": 0,
        "suffix": " M",
        "placement": 1000
      },
      "reads_mapped": {
        "title": "Reads mapped",
        "description": "Reads mapped in the bam file (millions)",
        "shared_key": "read_count",
        "hidden": false,
        "namespace": "Samtools Flagstat: stats",
        "clean_rid": "samtools_flagstat_stats-reads_mapped",
        "rid": "samtools_flagstat_stats-reads_mapped",
        "modify": null,
        "min": 0,
        "suffix": " M",
        "scale": "GnBu",
        "placement": 1000
      },
      "reads_mapped_percent": {
        "title": "% Mapped",
        "description": "% Mapped reads",
        "max": 100,
        "min": 0,
        "suffix": "%",
        "scale": "RdYlGn",
        "hidden": false,
        "namespace": "Samtools Flagstat: stats",
        "clean_rid": "samtools_flagstat_stats-reads_mapped_percent",
        "rid": "samtools_flagstat_stats-reads_mapped_percent",
        "placement": 1000
      },
      "reads_properly_paired_percent": {
        "title": "% Proper pairs",
        "description": "% Properly paired reads",
        "max": 100,
        "min": 0,
        "suffix": "%",
        "scale": "RdYlGn",
        "hidden": false,
        "namespace": "Samtools Flagstat: stats",
        "clean_rid": "samtools_flagstat_stats-reads_properly_paired_percent",
        "rid": "samtools_flagstat_stats-reads_properly_paired_percent",
        "placement": 1000
      },
      "reads_MQ0_percent": {
        "title": "% MapQ 0 reads",
        "description": "% of reads that are ambiguously placed (MapQ=0)",
        "max": 100,
        "min": 0,
        "suffix": "%",
        "scale": "OrRd",
        "hidden": true,
        "namespace": "Samtools Flagstat: stats",
        "clean_rid": "samtools_flagstat_stats-reads_MQ0_percent",
        "rid": "samtools_flagstat_stats-reads_MQ0_percent",
        "placement": 1000
      },
      "raw_total_sequences": {
        "title": "Total seqs",
        "description": "Total sequences in the bam file (millions)",
        "shared_key": "read_count",
        "hidden": false,
        "namespace": "Samtools Flagstat: stats",
        "clean_rid": "samtools_flagstat_stats-raw_total_sequences",
        "rid": "samtools_flagstat_stats-raw_total_sequences",
        "modify": null,
        "min": 0,
        "suffix": " M",
        "scale": "GnBu",
        "placement": 1000
      },
      "insert_size_average": {
        "title": "Mean insert",
        "description": "Average insert size",
        "suffix": "bp",
        "format": "{:,.1f}",
        "scale": "Oranges",
        "hidden": true,
        "namespace": "Samtools Flagstat: stats",
        "clean_rid": "samtools_flagstat_stats-insert_size_average",
        "rid": "samtools_flagstat_stats-insert_size_average",
        "min": null,
        "placement": 1000
      }
    },
    "mosdepth": {
      "1_x_pc": {
        "title": "\u2265 1X",
        "description": "Fraction of genome with at least 1X coverage",
        "max": 100,
        "min": 0,
        "suffix": "%",
        "scale": "RdYlGn",
        "hidden": true,
        "namespace": "Mosdepth",
        "clean_rid": "mosdepth-1_x_pc",
        "rid": "mosdepth-1_x_pc",
        "placement": 1000
      },
      "5_x_pc": {
        "title": "\u2265 5X",
        "description": "Fraction of genome with at least 5X coverage",
        "max": 100,
        "min": 0,
        "suffix": "%",
        "scale": "RdYlGn",
        "hidden": true,
        "namespace": "Mosdepth",
        "clean_rid": "mosdepth-5_x_pc",
        "rid": "mosdepth-5_x_pc",
        "placement": 1000
      },
      "10_x_pc": {
        "title": "\u2265 10X",
        "description": "Fraction of genome with at least 10X coverage",
        "max": 100,
        "min": 0,
        "suffix": "%",
        "scale": "RdYlGn",
        "hidden": true,
        "namespace": "Mosdepth",
        "clean_rid": "mosdepth-10_x_pc",
        "rid": "mosdepth-10_x_pc",
        "placement": 1000
      },
      "30_x_pc": {
        "title": "\u2265 30X",
        "description": "Fraction of genome with at least 30X coverage",
        "max": 100,
        "min": 0,
        "suffix": "%",
        "scale": "RdYlGn",
        "hidden": false,
        "namespace": "Mosdepth",
        "clean_rid": "mosdepth-30_x_pc",
        "rid": "mosdepth-30_x_pc",
        "placement": 1000
      },
      "50_x_pc": {
        "title": "\u2265 50X",
        "description": "Fraction of genome with at least 50X coverage",
        "max": 100,
        "min": 0,
        "suffix": "%",
        "scale": "RdYlGn",
        "hidden": true,
        "namespace": "Mosdepth",
        "clean_rid": "mosdepth-50_x_pc",
        "rid": "mosdepth-50_x_pc",
        "placement": 1000
      },
      "median_coverage": {
        "title": "Median",
        "description": "Median coverage",
        "min": 0,
        "suffix": "X",
        "scale": "BuPu",
        "namespace": "Mosdepth",
        "clean_rid": "mosdepth-median_coverage",
        "rid": "mosdepth-median_coverage",
        "placement": 1000
      },
      "mean_coverage": {
        "title": "Mean Cov.",
        "description": "Mean coverage",
        "min": 0,
        "suffix": "X",
        "scale": "BuPu",
        "namespace": "Mosdepth"
      },
      "min_coverage": {
        "title": "Min Cov.",
        "description": "Minimum coverage",
        "min": 0,
        "suffix": "X",
        "scale": "BuPu",
        "hidden": true,
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        "downstream_gene_variant_percent": 7.249467,
        "intergenic_region": 2.0,
        "intergenic_region_percent": 0.426439,
        "intragenic_variant": 23.0,
        "intragenic_variant_percent": 4.904051,
        "intron_variant": 231.0,
        "intron_variant_percent": 49.253731,
        "missense_variant": 58.0,
        "missense_variant_percent": 12.366738,
        "non_coding_transcript_exon_variant": 11.0,
        "non_coding_transcript_exon_variant_percent": 2.345416,
        "splice_acceptor_variant": 1.0,
        "splice_acceptor_variant_percent": 0.21322,
        "splice_donor_variant": 1.0,
        "splice_donor_variant_percent": 0.21322,
        "splice_region_variant": 11.0,
        "splice_region_variant_percent": 2.345416,
        "stop_gained": 1.0,
        "stop_gained_percent": 0.21322,
        "stop_lost": 1.0,
        "stop_lost_percent": 0.21322,
        "synonymous_variant": 35.0,
        "synonymous_variant_percent": 7.462687,
        "upstream_gene_variant": 45.0,
        "upstream_gene_variant_percent": 9.594883,
        "DOWNSTREAM": 34.0,
        "DOWNSTREAM_percent": 7.45614,
        "EXON": 105.0,
        "EXON_percent": 23.026316,
        "INTERGENIC": 2.0,
        "INTERGENIC_percent": 0.438596,
        "INTRON": 219.0,
        "INTRON_percent": 48.026316,
        "SPLICE_SITE_ACCEPTOR": 1.0,
        "SPLICE_SITE_ACCEPTOR_percent": 0.219298,
        "SPLICE_SITE_DONOR": 1.0,
        "SPLICE_SITE_DONOR_percent": 0.219298,
        "SPLICE_SITE_REGION": 11.0,
        "SPLICE_SITE_REGION_percent": 2.412281,
        "TRANSCRIPT": 23.0,
        "TRANSCRIPT_percent": 5.04386,
        "UPSTREAM": 45.0,
        "UPSTREAM_percent": 9.868421,
        "UTR_3_PRIME": 10.0,
        "UTR_3_PRIME_percent": 2.192982,
        "UTR_5_PRIME": 5.0,
        "UTR_5_PRIME_percent": 1.096491,
        "Transitions": 310.0,
        "Transversions": 290.0,
        "Ts_Tv_ratio": 1.068966,
        "Het": 0.0,
        "Hom": 0.0,
        "Missing": 300.0
      },
      "Sig_18_Blood.deconflicted_germline_custom.ann_snpEff": {
        "Number_of_variants_before_filter": 395.0,
        "Number_of_known_variants (i.e. non-empty ID)": 391.0,
        "Number_of_known_variants (i.e. non-empty ID)_percent": 98.987342,
        "Number_of_effects": 605.0,
        "Genome_total_length": 63147197748.0,
        "Genome_effective_length": 46709983.0,
        "Change_rate": 118253.0,
        "HIGH": 9.0,
        "HIGH_percent": 1.487603,
        "LOW": 139.0,
        "LOW_percent": 22.975207,
        "MODERATE": 156.0,
        "MODERATE_percent": 25.785124,
        "MODIFIER": 301.0,
        "MODIFIER_percent": 49.752066,
        "MISSENSE": 149.0,
        "MISSENSE_percent": 52.280702,
        "NONSENSE": 2.0,
        "NONSENSE_percent": 0.701754,
        "SILENT": 134.0,
        "SILENT_percent": 47.017544,
        "Missense_Silent_ratio": 1.11194,
        "3_prime_UTR_variant": 7.0,
        "3_prime_UTR_variant_percent": 1.145663,
        "5_prime_UTR_premature_start_codon_gain_variant": 1.0,
        "5_prime_UTR_premature_start_codon_gain_variant_percent": 0.163666,
        "5_prime_UTR_variant": 7.0,
        "5_prime_UTR_variant_percent": 1.145663,
        "conservative_inframe_insertion": 1.0,
        "conservative_inframe_insertion_percent": 0.163666,
        "disruptive_inframe_deletion": 3.0,
        "disruptive_inframe_deletion_percent": 0.490998,
        "disruptive_inframe_insertion": 3.0,
        "disruptive_inframe_insertion_percent": 0.490998,
        "downstream_gene_variant": 47.0,
        "downstream_gene_variant_percent": 7.692308,
        "frameshift_variant": 7.0,
        "frameshift_variant_percent": 1.145663,
        "intragenic_variant": 31.0,
        "intragenic_variant_percent": 5.07365,
        "intron_variant": 142.0,
        "intron_variant_percent": 23.240589,
        "missense_variant": 149.0,
        "missense_variant_percent": 24.386252,
        "non_coding_transcript_exon_variant": 24.0,
        "non_coding_transcript_exon_variant_percent": 3.927987,
        "splice_region_variant": 8.0,
        "splice_region_variant_percent": 1.309329,
        "stop_gained": 2.0,
        "stop_gained_percent": 0.327332,
        "synonymous_variant": 134.0,
        "synonymous_variant_percent": 21.93126,
        "upstream_gene_variant": 45.0,
        "upstream_gene_variant_percent": 7.364975,
        "DOWNSTREAM": 47.0,
        "DOWNSTREAM_percent": 7.768595,
        "EXON": 319.0,
        "EXON_percent": 52.727273,
        "INTRON": 142.0,
        "INTRON_percent": 23.471074,
        "SPLICE_SITE_REGION": 6.0,
        "SPLICE_SITE_REGION_percent": 0.991736,
        "TRANSCRIPT": 31.0,
        "TRANSCRIPT_percent": 5.123967,
        "UPSTREAM": 45.0,
        "UPSTREAM_percent": 7.438017,
        "UTR_3_PRIME": 7.0,
        "UTR_3_PRIME_percent": 1.157025,
        "UTR_5_PRIME": 8.0,
        "UTR_5_PRIME_percent": 1.322314,
        "Transitions": 381.0,
        "Transversions": 133.0,
        "Ts_Tv_ratio": 2.864662,
        "Het": 241.0,
        "Hom": 154.0,
        "Missing": 0.0
      },
      "Sig_18_Blood_custom.ann_snpEff": {
        "Number_of_variants_before_filter": 4.0,
        "Number_of_known_variants (i.e. non-empty ID)": 0.0,
        "Number_of_known_variants (i.e. non-empty ID)_percent": 0.0,
        "Number_of_effects": 16.0,
        "Genome_total_length": 63147197748.0,
        "Genome_effective_length": 387351139.0,
        "Change_rate": 193675569.0,
        "HIGH": 10.0,
        "HIGH_percent": 62.5,
        "LOW": 1.0,
        "LOW_percent": 6.25,
        "MODIFIER": 5.0,
        "MODIFIER_percent": 31.25,
        "Missense_Silent_ratio": 0.0,
        "bidirectional_gene_fusion": 1.0,
        "bidirectional_gene_fusion_percent": 5.555556,
        "conservative_inframe_deletion": 1.0,
        "conservative_inframe_deletion_percent": 5.555556,
        "downstream_gene_variant": 1.0,
        "downstream_gene_variant_percent": 5.555556,
        "exon_loss_variant": 7.0,
        "exon_loss_variant_percent": 38.888889,
        "gene_fusion": 1.0,
        "gene_fusion_percent": 5.555556,
        "intron_variant": 3.0,
        "intron_variant_percent": 16.666667,
        "non_coding_transcript_exon_variant": 1.0,
        "non_coding_transcript_exon_variant_percent": 5.555556,
        "splice_region_variant": 1.0,
        "splice_region_variant_percent": 5.555556,
        "start_lost": 1.0,
        "start_lost_percent": 5.555556,
        "upstream_gene_variant": 1.0,
        "upstream_gene_variant_percent": 5.555556,
        "DOWNSTREAM": 1.0,
        "DOWNSTREAM_percent": 6.25,
        "EXON": 8.0,
        "EXON_percent": 50.0,
        "GENE": 2.0,
        "GENE_percent": 12.5,
        "INTRON": 3.0,
        "INTRON_percent": 18.75,
        "SPLICE_SITE_REGION": 1.0,
        "SPLICE_SITE_REGION_percent": 6.25,
        "UPSTREAM": 1.0,
        "UPSTREAM_percent": 6.25,
        "Transitions": 0.0,
        "Transversions": 0.0,
        "Ts_Tv_ratio": 0.0,
        "Het": 2.0,
        "Hom": 0.0,
        "Missing": 0.0
      },
      "custom_Sig_18_tumor_normal.manta.diploid_sv_custom.ann_snpEff": {
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        "Number_of_known_variants (i.e. non-empty ID)": 4.0,
        "Number_of_known_variants (i.e. non-empty ID)_percent": 66.666667,
        "Number_of_effects": 19.0,
        "Genome_total_length": 63147197748.0,
        "Genome_effective_length": 46709983.0,
        "Change_rate": 7784997.0,
        "HIGH": 12.0,
        "HIGH_percent": 63.157895,
        "MODERATE": 1.0,
        "MODERATE_percent": 5.263158,
        "MODIFIER": 6.0,
        "MODIFIER_percent": 31.578947,
        "Missense_Silent_ratio": 0.0,
        "bidirectional_gene_fusion": 12.0,
        "bidirectional_gene_fusion_percent": 63.157895,
        "conservative_inframe_deletion": 1.0,
        "conservative_inframe_deletion_percent": 5.263158,
        "downstream_gene_variant": 1.0,
        "downstream_gene_variant_percent": 5.263158,
        "intragenic_variant": 1.0,
        "intragenic_variant_percent": 5.263158,
        "intron_variant": 2.0,
        "intron_variant_percent": 10.526316,
        "upstream_gene_variant": 2.0,
        "upstream_gene_variant_percent": 10.526316,
        "DOWNSTREAM": 1.0,
        "DOWNSTREAM_percent": 5.263158,
        "EXON": 1.0,
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        "GENE": 12.0,
        "GENE_percent": 63.157895,
        "INTRON": 2.0,
        "INTRON_percent": 10.526316,
        "TRANSCRIPT": 1.0,
        "TRANSCRIPT_percent": 5.263158,
        "UPSTREAM": 2.0,
        "UPSTREAM_percent": 10.526316,
        "Transitions": 0.0,
        "Transversions": 0.0,
        "Ts_Tv_ratio": 0.0,
        "Het": 5.0,
        "Hom": 1.0,
        "Missing": 0.0
      },
      "custom_Sig_18_tumor_normal.manta.somatic_sv_custom.ann_snpEff": {
        "Number_of_variants_before_filter": 0.0,
        "Number_of_known_variants (i.e. non-empty ID)": 0.0,
        "Number_of_known_variants (i.e. non-empty ID)_percent": 0.0,
        "Number_of_effects": 0.0,
        "Genome_total_length": 63147197748.0,
        "Genome_effective_length": 0.0,
        "Change_rate": 0.0,
        "Missense_Silent_ratio": 0.0,
        "Transitions": 0.0,
        "Transversions": 0.0,
        "Ts_Tv_ratio": 0.0
      },
      "custom_Sig_18_tumor_normal.strelka.somatic_indels_custom.ann_snpEff": {
        "Number_of_variants_before_filter": 88.0,
        "Number_of_known_variants (i.e. non-empty ID)": 0.0,
        "Number_of_known_variants (i.e. non-empty ID)_percent": 0.0,
        "Number_of_effects": 129.0,
        "Genome_total_length": 63147197748.0,
        "Genome_effective_length": 46709983.0,
        "Change_rate": 530795.0,
        "HIGH": 8.0,
        "HIGH_percent": 6.20155,
        "LOW": 9.0,
        "LOW_percent": 6.976744,
        "MODERATE": 8.0,
        "MODERATE_percent": 6.20155,
        "MODIFIER": 104.0,
        "MODIFIER_percent": 80.620155,
        "Missense_Silent_ratio": 0.0,
        "3_prime_UTR_variant": 2.0,
        "3_prime_UTR_variant_percent": 1.449275,
        "5_prime_UTR_variant": 1.0,
        "5_prime_UTR_variant_percent": 0.724638,
        "conservative_inframe_deletion": 1.0,
        "conservative_inframe_deletion_percent": 0.724638,
        "disruptive_inframe_deletion": 3.0,
        "disruptive_inframe_deletion_percent": 2.173913,
        "disruptive_inframe_insertion": 4.0,
        "disruptive_inframe_insertion_percent": 2.898551,
        "downstream_gene_variant": 13.0,
        "downstream_gene_variant_percent": 9.42029,
        "frameshift_variant": 8.0,
        "frameshift_variant_percent": 5.797101,
        "intergenic_region": 1.0,
        "intergenic_region_percent": 0.724638,
        "intragenic_variant": 5.0,
        "intragenic_variant_percent": 3.623188,
        "intron_variant": 75.0,
        "intron_variant_percent": 54.347826,
        "non_coding_transcript_exon_variant": 3.0,
        "non_coding_transcript_exon_variant_percent": 2.173913,
        "splice_region_variant": 9.0,
        "splice_region_variant_percent": 6.521739,
        "upstream_gene_variant": 13.0,
        "upstream_gene_variant_percent": 9.42029,
        "DOWNSTREAM": 13.0,
        "DOWNSTREAM_percent": 10.077519,
        "EXON": 19.0,
        "EXON_percent": 14.728682,
        "INTERGENIC": 1.0,
        "INTERGENIC_percent": 0.775194,
        "INTRON": 66.0,
        "INTRON_percent": 51.162791,
        "SPLICE_SITE_REGION": 9.0,
        "SPLICE_SITE_REGION_percent": 6.976744,
        "TRANSCRIPT": 5.0,
        "TRANSCRIPT_percent": 3.875969,
        "UPSTREAM": 13.0,
        "UPSTREAM_percent": 10.077519,
        "UTR_3_PRIME": 2.0,
        "UTR_3_PRIME_percent": 1.550388,
        "UTR_5_PRIME": 1.0,
        "UTR_5_PRIME_percent": 0.775194,
        "Transitions": 0.0,
        "Transversions": 0.0,
        "Ts_Tv_ratio": 0.0,
        "Het": 0.0,
        "Hom": 0.0,
        "Missing": 88.0
      },
      "custom_Sig_18_tumor_normal.strelka.somatic_snvs_custom.ann_snpEff": {
        "Number_of_variants_before_filter": 237.0,
        "Number_of_known_variants (i.e. non-empty ID)": 0.0,
        "Number_of_known_variants (i.e. non-empty ID)_percent": 0.0,
        "Number_of_effects": 381.0,
        "Genome_total_length": 63147197748.0,
        "Genome_effective_length": 46709983.0,
        "Change_rate": 197088.0,
        "HIGH": 2.0,
        "HIGH_percent": 0.524934,
        "LOW": 34.0,
        "LOW_percent": 8.923885,
        "MODERATE": 52.0,
        "MODERATE_percent": 13.648294,
        "MODIFIER": 293.0,
        "MODIFIER_percent": 76.902887,
        "MISSENSE": 52.0,
        "MISSENSE_percent": 66.666667,
        "NONSENSE": 2.0,
        "NONSENSE_percent": 2.564103,
        "SILENT": 24.0,
        "SILENT_percent": 30.769231,
        "Missense_Silent_ratio": 2.166667,
        "3_prime_UTR_variant": 9.0,
        "3_prime_UTR_variant_percent": 2.290076,
        "5_prime_UTR_premature_start_codon_gain_variant": 1.0,
        "5_prime_UTR_premature_start_codon_gain_variant_percent": 0.254453,
        "5_prime_UTR_variant": 4.0,
        "5_prime_UTR_variant_percent": 1.017812,
        "downstream_gene_variant": 33.0,
        "downstream_gene_variant_percent": 8.396947,
        "intergenic_region": 1.0,
        "intergenic_region_percent": 0.254453,
        "intragenic_variant": 22.0,
        "intragenic_variant_percent": 5.597964,
        "intron_variant": 189.0,
        "intron_variant_percent": 48.091603,
        "missense_variant": 52.0,
        "missense_variant_percent": 13.231552,
        "non_coding_transcript_exon_variant": 5.0,
        "non_coding_transcript_exon_variant_percent": 1.272265,
        "splice_region_variant": 12.0,
        "splice_region_variant_percent": 3.053435,
        "stop_gained": 2.0,
        "stop_gained_percent": 0.508906,
        "synonymous_variant": 24.0,
        "synonymous_variant_percent": 6.10687,
        "upstream_gene_variant": 39.0,
        "upstream_gene_variant_percent": 9.923664,
        "DOWNSTREAM": 33.0,
        "DOWNSTREAM_percent": 8.661417,
        "EXON": 83.0,
        "EXON_percent": 21.784777,
        "INTERGENIC": 1.0,
        "INTERGENIC_percent": 0.262467,
        "INTRON": 180.0,
        "INTRON_percent": 47.244094,
        "SPLICE_SITE_REGION": 9.0,
        "SPLICE_SITE_REGION_percent": 2.362205,
        "TRANSCRIPT": 22.0,
        "TRANSCRIPT_percent": 5.774278,
        "UPSTREAM": 39.0,
        "UPSTREAM_percent": 10.23622,
        "UTR_3_PRIME": 9.0,
        "UTR_3_PRIME_percent": 2.362205,
        "UTR_5_PRIME": 5.0,
        "UTR_5_PRIME_percent": 1.312336,
        "Transitions": 262.0,
        "Transversions": 212.0,
        "Ts_Tv_ratio": 1.235849,
        "Het": 0.0,
        "Hom": 0.0,
        "Missing": 237.0
      }
    },
    "vep": {
      "HCC1395_BL.deconflicted_germline_custom.ann_snpEff_VEP.ann": {
        "Variant classes": {
          "insertion": 9,
          "deletion": 11,
          "SNV": 334
        },
        "Consequences (most severe)": {
          "stop_gained": 1,
          "frameshift_variant": 5,
          "stop_lost": 1,
          "inframe_insertion": 3,
          "inframe_deletion": 2,
          "missense_variant": 139,
          "splice_region_variant": 2,
          "synonymous_variant": 125,
          "5_prime_UTR_variant": 9,
          "3_prime_UTR_variant": 7,
          "non_coding_transcript_exon_variant": 7,
          "intron_variant": 51,
          "intergenic_variant": 2
        },
        "Consequences (all)": {
          "stop_gained": 1,
          "frameshift_variant": 5,
          "inframe_insertion": 2,
          "inframe_deletion": 2,
          "missense_variant": 128,
          "splice_region_variant": 4,
          "synonymous_variant": 127,
          "5_prime_UTR_variant": 3,
          "3_prime_UTR_variant": 8,
          "non_coding_transcript_exon_variant": 16,
          "intron_variant": 152,
          "non_coding_transcript_variant": 37,
          "upstream_gene_variant": 54,
          "downstream_gene_variant": 62,
          "regulatory_region_variant": 26,
          "intergenic_variant": 2
        },
        "Coding consequences": {
          "stop_gained": 1,
          "frameshift_variant": 5,
          "inframe_insertion": 2,
          "inframe_deletion": 2,
          "missense_variant": 128,
          "synonymous_variant": 127
        },
        "SIFT summary": {
          "deleterious_low_confidence": 11,
          "deleterious": 22,
          "tolerated_low_confidence": 24,
          "tolerated": 70
        },
        "PolyPhen summary": {
          "possibly_damaging": 7,
          "probably_damaging": 12,
          "unknown": 21,
          "benign": 84
        },
        "Variants by chromosome": {
          "chr21": 354
        },
        "Position in protein": {
          "00-10%": 27,
          "10-20%": 31,
          "20-30%": 22,
          "30-40%": 29,
          "40-50%": 29,
          "50-60%": 22,
          "60-70%": 26,
          "70-80%": 27,
          "80-90%": 27,
          "90-100%": 25
        },
        "General statistics": {
          "Lines of input read": 354,
          "Variants processed": 354,
          "Variants filtered out": 0,
          "Novel variants": 0,
          "Existing variants": 354,
          "Overlapped genes": 193,
          "Overlapped transcripts": 201,
          "Overlapped regulatory features": 16
        }
      },
      "HCC1395_BL_custom.ann_snpEff_VEP.ann": {
        "Variant classes": {
          "copy_number_variation": 1,
          "deletion": 2
        },
        "Consequences (most severe)": {
          "transcript_ablation": 1,
          "intron_variant": 2
        },
        "Consequences (all)": {
          "stop_lost": 1,
          "feature_truncation": 2,
          "coding_sequence_variant": 1,
          "5_prime_UTR_variant": 1,
          "3_prime_UTR_variant": 1,
          "non_coding_transcript_exon_variant": 1,
          "intron_variant": 4,
          "NMD_transcript_variant": 1,
          "downstream_gene_variant": 1,
          "regulatory_region_variant": 1
        },
        "Coding consequences": {
          "stop_lost": 1,
          "coding_sequence_variant": 1
        },
        "Variants by chromosome": {
          "chr1": 1,
          "chr9": 1,
          "chrX": 1
        },
        "General statistics": {
          "Lines of input read": 4,
          "Variants processed": 3,
          "Variants filtered out": 0,
          "Novel variants": 0,
          "Existing variants": 3,
          "Overlapped genes": 6,
          "Overlapped transcripts": 6,
          "Overlapped regulatory features": 1
        }
      },
      "HCC1395_tumor_vs_HCC1395_BL.manta.diploid_sv_custom.ann_snpEff_VEP.ann": {
        "Variant classes": {
          "indel": 1,
          "chromosome_breakpoint": 2
        },
        "Consequences (most severe)": {
          "feature_truncation": 2,
          "intron_variant": 1
        },
        "Consequences (all)": {
          "feature_truncation": 2,
          "intron_variant": 3,
          "upstream_gene_variant": 2
        },
        "Variants by chromosome": {
          "chr21": 3
        },
        "General statistics": {
          "Lines of input read": 3,
          "Variants processed": 3,
          "Variants filtered out": 0,
          "Novel variants": 0,
          "Existing variants": 3,
          "Overlapped genes": 4,
          "Overlapped transcripts": 4,
          "Overlapped regulatory features": 0
        }
      },
      "HCC1395_tumor_vs_HCC1395_BL.manta.somatic_sv_custom.ann_snpEff_VEP.ann": {
        "Variant classes": {
          "chromosome_breakpoint": 2
        },
        "Consequences (most severe)": {
          "feature_truncation": 2
        },
        "Consequences (all)": {
          "feature_truncation": 2,
          "3_prime_UTR_variant": 2,
          "downstream_gene_variant": 2
        },
        "Variants by chromosome": {
          "chr21": 2
        },
        "General statistics": {
          "Lines of input read": 2,
          "Variants processed": 2,
          "Variants filtered out": 0,
          "Novel variants": 0,
          "Existing variants": 2,
          "Overlapped genes": 2,
          "Overlapped transcripts": 2,
          "Overlapped regulatory features": 0
        }
      },
      "HCC1395_tumor_vs_HCC1395_BL.strelka.somatic_indels_custom.ann_snpEff_VEP.ann": {
        "Variant classes": {
          "insertion": 19,
          "deletion": 23
        },
        "Consequences (most severe)": {
          "splice_acceptor_variant": 1,
          "inframe_insertion": 1,
          "inframe_deletion": 5,
          "splice_region_variant": 1,
          "splice_polypyrimidine_tract_variant": 5,
          "5_prime_UTR_variant": 2,
          "3_prime_UTR_variant": 2,
          "intron_variant": 25
        },
        "Consequences (all)": {
          "inframe_insertion": 1,
          "inframe_deletion": 4,
          "splice_region_variant": 1,
          "splice_polypyrimidine_tract_variant": 6,
          "3_prime_UTR_variant": 2,
          "intron_variant": 39,
          "non_coding_transcript_variant": 3,
          "upstream_gene_variant": 7,
          "downstream_gene_variant": 11,
          "regulatory_region_variant": 5
        },
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          "inframe_deletion": 4
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        "Variants by chromosome": {
          "chr21": 42
        },
        "Position in protein": {
          "00-10%": 2,
          "10-20%": 0,
          "20-30%": 0,
          "30-40%": 1,
          "40-50%": 0,
          "50-60%": 0,
          "60-70%": 0,
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          "80-90%": 0,
          "90-100%": 1
        },
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          "Variants processed": 42,
          "Variants filtered out": 0,
          "Novel variants": 0,
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        }
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          "splice_donor_variant": 1,
          "stop_gained": 2,
          "stop_lost": 1,
          "missense_variant": 62,
          "splice_donor_5th_base_variant": 4,
          "splice_region_variant": 5,
          "splice_donor_region_variant": 2,
          "splice_polypyrimidine_tract_variant": 8,
          "synonymous_variant": 32,
          "5_prime_UTR_variant": 6,
          "3_prime_UTR_variant": 12,
          "non_coding_transcript_exon_variant": 23,
          "intron_variant": 140,
          "intergenic_variant": 1
        },
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          "splice_donor_variant": 1,
          "stop_gained": 1,
          "stop_lost": 1,
          "missense_variant": 56,
          "splice_donor_5th_base_variant": 4,
          "splice_region_variant": 6,
          "splice_donor_region_variant": 2,
          "splice_polypyrimidine_tract_variant": 11,
          "synonymous_variant": 32,
          "5_prime_UTR_variant": 5,
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          "non_coding_transcript_exon_variant": 10,
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        },
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          "possibly_damaging": 5,
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        },
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          "10-20%": 8,
          "20-30%": 9,
          "30-40%": 13,
          "40-50%": 6,
          "50-60%": 13,
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          "70-80%": 4,
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          "Novel variants": 0,
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        }
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          "deletion": 14,
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          "inframe_insertion": 3,
          "inframe_deletion": 3,
          "missense_variant": 150,
          "splice_region_variant": 4,
          "synonymous_variant": 128,
          "5_prime_UTR_variant": 8,
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          "missense_variant": 140,
          "splice_region_variant": 6,
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          "10-20%": 34,
          "20-30%": 24,
          "30-40%": 31,
          "40-50%": 26,
          "50-60%": 30,
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          "chr9": 1,
          "chrX": 1
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        }
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          "10-20%": 1,
          "20-30%": 0,
          "30-40%": 2,
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          "50-60%": 3,
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          "splice_donor_5th_base_variant": 2,
          "splice_region_variant": 3,
          "splice_donor_region_variant": 4,
          "splice_polypyrimidine_tract_variant": 8,
          "synonymous_variant": 23,
          "5_prime_UTR_variant": 5,
          "3_prime_UTR_variant": 11,
          "non_coding_transcript_exon_variant": 11,
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          "upstream_gene_variant": 1,
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          "splice_donor_5th_base_variant": 2,
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          "non_coding_transcript_variant": 32,
          "upstream_gene_variant": 50,
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          "deleterious_low_confidence": 9,
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          "10-20%": 10,
          "20-30%": 7,
          "30-40%": 7,
          "40-50%": 2,
          "50-60%": 19,
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          "70-80%": 8,
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          "90-100%": 4
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