Matplotlib created a temporary config/cache directory at /tmp/matplotlib-q4a1q_4e because the default path (/.config/matplotlib) is not a writable directory; it is highly recommended to set the MPLCONFIGDIR environment variable to a writable directory, in particular to speed up the import of Matplotlib and to better support multiprocessing. Fontconfig error: No writable cache directories Calling copy number with thresholds: -1.1 => 0, -0.25 => 1, 0.2 => 2, 0.7 => 3 Wrote HCC1395_tumor.recalibrated.somatic.call.cns with 7 regions Matplotlib created a temporary config/cache directory at /tmp/matplotlib-q0jkiwsh because the default path (/.config/matplotlib) is not a writable directory; it is highly recommended to set the MPLCONFIGDIR environment variable to a writable directory, in particular to speed up the import of Matplotlib and to better support multiprocessing. Fontconfig error: No writable cache directories