Downloading: s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta
  Downloading: s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Annotation/GATKBundle/dbsnp_146.hg38.vcf.gz.tbi
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/ea/9e377f3df37d5a6907c33198b9eb1e/.command.sh
  Downloading: s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Annotation/intervals/regression_intervals/scatter/chr21_44120631-44120778.bed.gz
  Downloading: s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Sequence/WholeGenomeFasta/Homo_sapiens_assembly38.fasta.fai
  Downloading: s3://natera-platform-sandbox/pipeline-inputs/test_sarek/end_to_end_regression/01_preprocess_regression_fastqs/regression_preprocess__60492e9--20260310-034416/alignments/recalibrated/HCC1395_BL/HCC1395_BL.recalibrated.bam
  Downloading: s3://natera-platform-sandbox/pipeline-inputs/test_sarek/end_to_end_regression/01_preprocess_regression_fastqs/regression_preprocess__60492e9--20260310-034416/alignments/recalibrated/HCC1395_BL/HCC1395_BL.recalibrated.bam.bai
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/ea/9e377f3df37d5a6907c33198b9eb1e/.command.run
  Downloading: s3://natera-platform-sandbox/pipeline-resources/ngi-igenomes/igenomes/Homo_sapiens/GATK/GRCh38/Annotation/GATKBundle/dbsnp_146.hg38.vcf.gz
==> STAGING COMPLETE (9 inputs)

cmdline: /opt/conda/share/sentieon-202308.03-3/libexec/driver -r Homo_sapiens_assembly38.fasta -t 12 --interval chr21_44120631-44120778.bed.gz -i HCC1395_BL.recalibrated.bam --algo Haplotyper -d dbsnp_146.hg38.vcf.gz --emit_mode variant HCC1395_BL.haplotyper.chr21_44120631-44120778.bed.unfiltered.vcf.gz
This software is licensed to bgold@natera.com by Sentieon Inc.
progress 5% @chr21:44254617, elapsed 0.0s, est remaining 0.2s, peak mem 78MB, user 0.0s, sys 0.0s, output queue size 1
progress 10% @chr21:44286007, elapsed 0.0s, est remaining 0.4s, peak mem 96MB, user 0.2s, sys 0.0s, output queue size 40
progress 15% @chr21:44236867, elapsed 0.1s, est remaining 0.3s, peak mem 111MB, user 0.3s, sys 0.0s, output queue size 71
progress 20% @chr21:44456645, elapsed 0.1s, est remaining 0.2s, peak mem 117MB, user 0.4s, sys 0.0s, output queue size 98
progress 26% @chr21:44591387, elapsed 0.1s, est remaining 0.2s, peak mem 150MB, user 0.5s, sys 0.0s, output queue size 108
progress 33% @chr21:44224713, elapsed 0.1s, est remaining 0.3s, peak mem 162MB, user 0.6s, sys 0.1s, output queue size 112
progress 35% @chr21:44657980, elapsed 0.1s, est remaining 0.2s, peak mem 162MB, user 0.7s, sys 0.1s, output queue size 7
progress 41% @chr21:44573759, elapsed 0.2s, est remaining 0.3s, peak mem 216MB, user 1.6s, sys 0.1s, output queue size 29
progress 45% @chr21:44901492, elapsed 0.2s, est remaining 0.3s, peak mem 216MB, user 2.0s, sys 0.1s, output queue size 42
progress 50% @chr21:44891809, elapsed 0.2s, est remaining 0.2s, peak mem 216MB, user 2.1s, sys 0.1s, output queue size 70
progress 55% @chr21:45493163, elapsed 0.3s, est remaining 0.2s, peak mem 216MB, user 2.3s, sys 0.1s, output queue size 27
progress 60% @chr21:45986526, elapsed 0.3s, est remaining 0.2s, peak mem 216MB, user 2.4s, sys 0.1s, output queue size 29
progress 65% @chr21:46121061, elapsed 0.3s, est remaining 0.2s, peak mem 216MB, user 2.6s, sys 0.1s, output queue size 12
progress 70% @chr21:46131954, elapsed 0.3s, est remaining 0.1s, peak mem 216MB, user 2.8s, sys 0.1s, output queue size 20
progress 75% @chr21:46258939, elapsed 0.3s, est remaining 0.1s, peak mem 216MB, user 2.9s, sys 0.1s, output queue size 53
progress 80% @chr21:46346128, elapsed 0.4s, est remaining 0.1s, peak mem 216MB, user 3.1s, sys 0.2s, output queue size 84
progress 85% @chr21:46301999, elapsed 0.4s, est remaining 0.1s, peak mem 216MB, user 3.4s, sys 0.2s, output queue size 23
progress 90% @chr21:46430010, elapsed 0.4s, est remaining 0.0s, peak mem 216MB, user 3.4s, sys 0.2s, output queue size 24
progress 95% @chr21:46366584, elapsed 0.4s, est remaining 0.0s, peak mem 216MB, user 3.5s, sys 0.2s, output queue size 55
progress 100% @chr21:46602278, elapsed 0.4s, est remaining 0.0s, peak mem 216MB, user 3.6s, sys 0.2s, output queue size 11
sw version: sentieon-genomics-202308.03
os version: Linux 6.12.88
cpu vendor: GenuineIntel
 signature: 000a06d1
  features: bfebfbff 7ffefbff
  extended: f3bfb7ef fb417ffe
  amd bits: 2c100800 00000121
     brand: Intel(R) Xeon(R) 6975P-C
threads: 12 max 384
algo: Haplotyper
license: sentieon:Haplotyper=12
input file size: 163002590
output file size: 38710
reads: 1955548
contig: 516 intervals 92221 bases
"assemble": 96 calls 0.132 user 0.001 sys 0.223 real
"assemble_addRead": 96 calls 0.000 user 0.000 sys 0.010 real
"assemble_buildGraph": 205 calls 0.056 user 0.000 sys 0.112 real
"assemble_computecigar": 140 calls 0.095 user 0.013 sys 0.143 real
"assemble_kg_build_calcsize": 205 calls 0.033 user 0.000 sys 0.066 real
"assemble_kg_build_clear": 265 calls 0.010 user 0.000 sys 0.005 real
"assemble_kg_build_prepare": 410 calls 0.037 user 0.000 sys 0.051 real
"assemble_kg_build_threading": 145 calls 0.023 user 0.000 sys 0.044 real
"assemble_kg_op1": 145 calls 0.000 user 0.000 sys 0.010 real
"assemble_kg_op2": 145 calls 0.000 user 0.000 sys 0.003 real
"assemble_kg_op3": 145 calls 0.000 user 0.000 sys 0.003 real
"assemble_sg_clean": 140 calls 0.004 user 0.000 sys 0.012 real
"assemble_sg_create": 140 calls 0.005 user 0.000 sys 0.015 real
"checkGraph": 96 calls 0.000 user 0.000 sys 0.000 real
"findHaplotype": 96 calls 0.099 user 0.013 sys 0.147 real
active: 1044 calls 0.000 user 0.000 sys 0.003 real
advance: 528 calls 1.053 user 0.076 sys 1.380 real
annotate: 105 calls 0.007 user 0.000 sys 0.009 real
assemble_region: 96 calls 0.231 user 0.013 sys 0.380 real
build_variants: 95 calls 0.000 user 0.000 sys 0.000 real
calc: 1044 calls 0.112 user 0.007 sys 0.121 real
calc_region: 95 calls 1.327 user 0.044 sys 1.405 real
call_region: 95 calls 0.007 user 0.000 sys 0.015 real
clip_region: 191 calls 0.020 user 0.000 sys 0.018 real
done: 1 calls 0.001 user 0.000 sys 0.002 real
execute: 1 calls 0.002 user 0.000 sys 0.437 real
fetch: 1044 calls 0.034 user 0.000 sys 0.053 real
fetch_db: 95 calls 0.025 user 0.000 sys 0.029 real
fetch_ref: 1140 calls 0.007 user 0.000 sys 0.005 real
fetch_region: 96 calls 0.000 user 0.000 sys 0.004 real
idle: 48 calls 0.033 user 0.001 sys 12.501 real
init: 1 calls 0.048 user 0.001 sys 0.042 real
pairhmm: 430 calls 2.487 user 0.042 sys 2.741 real
realign: 197 calls 0.165 user 0.000 sys 0.171 real
region: 1044 calls 2.351 user 0.065 sys 2.438 real
tracker: 1044 calls 0.000 user 0.000 sys 0.003 real
trim_region: 96 calls 0.000 user 0.000 sys 0.001 real
overall: 226664448 mem 4.914 user 0.190 sys 1.540 real
ls: cannot access '*.g.vcf.gz': No such file or directory
ls: cannot access '*.g.vcf.gz.tbi': No such file or directory