Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/a9/ae727d92af94ebf87bd72cbff8b238/Sig_18_tissue.recalibrated.cns
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/0d/c1fc361e42bba1255fbeb567e226af/.command.sh
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/0d/c1fc361e42bba1255fbeb567e226af/.command.run
==> STAGING COMPLETE (3 inputs)

Matplotlib created a temporary config/cache directory at /tmp/matplotlib-dp4e7spr because the default path (/.config/matplotlib) is not a writable directory; it is highly recommended to set the MPLCONFIGDIR environment variable to a writable directory, in particular to speed up the import of Matplotlib and to better support multiprocessing.
Fontconfig error: No writable cache directories
Calling copy number with thresholds: -1.1 => 0, -0.25 => 1, 0.2 => 2, 0.7 => 3
Wrote Sig_18_tissue.recalibrated.somatic.call.cns with 6 regions
Matplotlib created a temporary config/cache directory at /tmp/matplotlib-z3nniipv because the default path (/.config/matplotlib) is not a writable directory; it is highly recommended to set the MPLCONFIGDIR environment variable to a writable directory, in particular to speed up the import of Matplotlib and to better support multiprocessing.
Fontconfig error: No writable cache directories