↓from,to→		A	C	G	T	total
A	0.997965	0.001110	0.001379	0.000757	225559599
C	0.000468	0.997360	0.000678	0.000555	285314058
G	0.000547	0.000685	0.997391	0.000468	287340120
T	0.000755	0.001374	0.001100	0.997918	222801030